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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:food bleaching agent
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Accession:CHEBI:78003 term browser browse the term
Definition:A food additive that is used for the purpose of decolourising food.
Synonyms:related_synonym: food bleaching agents


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sulfur dioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of AGR2 mRNA CTD PMID:29621558 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433
JBrowse link
G ARC activity regulated cytoskeleton associated protein decreases expression ISO Sulfur Dioxide results in decreased expression of ARC mRNA CTD PMID:25534910 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
JBrowse link
G AREG amphiregulin multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of AREG mRNA CTD PMID:29621558 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of BAX protein; [Sulfur Dioxide co-treated with sodium arsenite] results in increased expression of BAX mRNA CTD PMID:27521637, PMID:30195209 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
ISO [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of BCL2 mRNA
Sulfur Dioxide results in decreased expression of BCL2 mRNA
CTD PMID:30195209 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BECN1 beclin 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] CTD PMID:30503585 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha decreases expression ISO Sulfur Dioxide results in decreased expression of CAMK2A protein modified form CTD PMID:25534910 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,291
JBrowse link
G CAPN1 calpain 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] CTD PMID:30503585 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
JBrowse link
G CASP1 caspase 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form] CTD PMID:30503585 NCBI chr11:105,025,443...105,035,591
Ensembl chr11:105,025,443...105,035,250
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G CASP3 caspase 3 multiple interactions
decreases activity
increases expression
ISO
EXP
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein; Sulfur Dioxide results in increased expression of and results in increased activity of CASP3 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP3 mRNA
Sulfur Dioxide results in decreased activity of CASP3 protein
[Sulfur Dioxide co-treated with sodium arsenite] results in increased activity of CASP3 protein; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein
Sulfur Dioxide results in increased expression of CASP3 mRNA
CTD PMID:19621461, PMID:21873648, PMID:26209559, PMID:30195209, PMID:30503585, PMID:31268311 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 increases expression
multiple interactions
ISO
EXP
Sulfur Dioxide results in increased expression of CASP8 mRNA
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP8 protein
CTD PMID:19621461, PMID:30503585, PMID:31268311 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 increases expression
multiple interactions
ISO
EXP
Sulfur Dioxide results in increased expression of CASP9 mRNA
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP9 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of CASP9 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP9 protein
CTD PMID:19621461, PMID:30503585, PMID:31268311 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases activity
multiple interactions
ISO Sulfur Dioxide results in decreased activity of CAT protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA]
CTD PMID:10871429, PMID:30503585 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL1 C-C motif chemokine ligand 1 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of CCL1 mRNA CTD PMID:29621558 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233
JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of CCL2 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]
CTD PMID:27565714, PMID:30503585 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL20 C-C motif chemokine ligand 20 decreases expression ISO Sulfur Dioxide results in decreased expression of CCL20 protein CTD PMID:27565714 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CDH2 cadherin 2 multiple interactions
decreases expression
ISO [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CDH2 protein
Sulfur Dioxide results in decreased expression of CDH2 protein
CTD PMID:27237588 NCBI chr18:27,932,878...28,177,130
Ensembl chr18:27,932,879...28,177,946
Ensembl chr18:27,932,879...28,177,946
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A multiple interactions
increases expression
decreases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A protein]
Sulfur Dioxide results in increased expression of CDKN2A protein
Sulfur Dioxide results in decreased expression of CDKN2A mRNA; Sulfur Dioxide results in decreased expression of CDKN2A protein
CTD PMID:19408242, PMID:19434695, PMID:20064080 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CLCA1 chloride channel accessory 1 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CLCA1 mRNA CTD PMID:29621558 NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259
Ensembl chr 1:86,468,368...86,500,259
JBrowse link
G CLDN11 claudin 11 decreases expression
multiple interactions
ISO Sulfur Dioxide results in decreased expression of CLDN11 protein
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CLDN11 protein
CTD PMID:27237588 NCBI chr 3:170,418,868...170,434,691
Ensembl chr 3:170,418,865...170,454,733
Ensembl chr 3:170,418,865...170,454,733
JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions ISO CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,359
JBrowse link
G COL11A1 collagen type XI alpha 1 chain multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of COL11A1 mRNA CTD PMID:29621558 NCBI chr 1:102,876,473...103,108,580
Ensembl chr 1:102,876,467...103,108,872
JBrowse link
G COX4I1 cytochrome c oxidase subunit 4I1 increases expression ISO Sulfur Dioxide results in increased expression of COX4I1 mRNA CTD PMID:22677886 NCBI chr16:85,799,695...85,807,068
Ensembl chr16:85,798,633...85,807,068
Ensembl chr16:85,798,633...85,807,068
JBrowse link
G CTNNA1 catenin alpha 1 multiple interactions
decreases expression
ISO [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CTNNA1 protein
Sulfur Dioxide results in decreased expression of CTNNA1 protein
CTD PMID:27237588 NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases expression ISO Sulfur Dioxide results in increased expression of CXCL1 protein CTD PMID:27565714 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CXCL11 mRNA CTD PMID:29621558 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415
JBrowse link
G CYCS cytochrome c, somatic multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein] CTD PMID:30503585 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity
decreases expression
ISO Sulfur Dioxide results in decreased activity of CYP1A1 protein
Sulfur Dioxide results in decreased expression of CYP1A1 mRNA
CTD PMID:16023800 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity
decreases expression
ISO Sulfur Dioxide results in decreased activity of CYP1A2 protein
Sulfur Dioxide results in decreased expression of CYP1A2 mRNA
CTD PMID:16023800 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of DDIT3 mRNA CTD PMID:31268311 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 affects expression ISO Sulfur Dioxide affects the expression of DLG4 protein CTD PMID:25534910 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,189,890...7,219,841
Ensembl chr17:7,189,890...7,219,841
Ensembl chr17:7,189,890...7,219,841
JBrowse link
G DNM1L dynamin 1 like multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of DNM1L protein CTD PMID:27521637 NCBI chr12:32,679,296...32,745,650
Ensembl chr12:32,679,200...32,745,650
JBrowse link
G DSG2 desmoglein 2 multiple interactions
decreases expression
ISO [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 mRNA; [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 protein
Sulfur Dioxide results in decreased expression of DSG2 mRNA; Sulfur Dioxide results in decreased expression of DSG2 protein
CTD PMID:27237588 NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,498,177...31,549,008
JBrowse link
G EDN1 endothelin 1 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of EDN1 mRNA; Sulfur Dioxide results in increased expression of EDN1 protein
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of EDN1 protein
CTD PMID:20083630, PMID:30090456 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G FIS1 fission, mitochondrial 1 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of FIS1 protein CTD PMID:27521637 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS protein
Sulfur Dioxide results in increased expression of FOS mRNA; Sulfur Dioxide results in increased expression of FOS protein
CTD PMID:19408242, PMID:19434695 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G GJA1 gap junction protein alpha 1 decreases expression
multiple interactions
ISO Sulfur Dioxide results in decreased expression of GJA1 protein
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of GJA1 protein
CTD PMID:27237588 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] CTD PMID:30503585 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA] CTD PMID:30503585 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression ISO Sulfur Dioxide results in decreased expression of GRIA1 mRNA CTD PMID:25534910 NCBI chr 5:153,490,670...153,813,873
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression ISO Sulfur Dioxide results in decreased expression of GRIA2 mRNA CTD PMID:25534910 NCBI chr 4:157,220,120...157,370,583
Ensembl chr 4:157,204,182...157,366,075
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression ISO Sulfur Dioxide results in decreased expression of GRIN1 mRNA CTD PMID:25534910 NCBI chr 9:137,139,092...137,168,759
Ensembl chr 9:137,139,154...137,168,756
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A decreases expression ISO Sulfur Dioxide results in decreased expression of GRIN2A mRNA CTD PMID:25534910 NCBI chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
decreases expression
increases cleavage
ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased cleavage of GRIN2B protein]
Sulfur Dioxide results in decreased expression of GRIN2B mRNA
CTD PMID:21873648, PMID:25534910 NCBI chr12:13,537,337...13,982,012
Ensembl chr12:13,437,942...13,982,002
Ensembl chr12:13,437,942...13,982,002
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein] CTD PMID:30503585 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HRAS HRas proto-oncogene, GTPase multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS protein]
Sulfur Dioxide results in increased expression of HRAS mRNA; Sulfur Dioxide results in increased expression of HRAS protein
CTD PMID:19408242, PMID:20064080 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,287
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO
EXP
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of HSPA5 mRNA
CTD PMID:30503585, PMID:31268311 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of ICAM1 mRNA; Sulfur Dioxide results in increased expression of ICAM1 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
CTD PMID:20083630, PMID:30503585 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of IFNG protein
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IFNG protein
CTD PMID:27565714, PMID:29621558 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of IKBKB mRNA CTD PMID:31268311 NCBI chr 8:42,270,727...42,332,460
Ensembl chr 8:42,271,302...42,332,653
JBrowse link
G IL10 interleukin 10 increases expression ISO Sulfur Dioxide results in increased expression of IL10 protein CTD PMID:27565714 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IL13 mRNA CTD PMID:29621558 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL17A interleukin 17A multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL17A protein CTD PMID:29621558 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL18 interleukin 18 increases expression ISO Sulfur Dioxide results in increased expression of IL18 protein CTD PMID:27565714 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of IL1B protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
CTD PMID:27565714, PMID:30503585 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 increases expression ISO Sulfur Dioxide results in increased expression of IL2 protein CTD PMID:27565714 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL4 interleukin 4 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL4 protein CTD PMID:29621558 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions
EXP
ISO
Sulfur Dioxide results in increased expression of IL6 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of IL6 protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of IL6 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]
CTD PMID:20056584, PMID:27565714, PMID:30503585, PMID:31268311 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN protein
Sulfur Dioxide results in increased expression of JUN mRNA; Sulfur Dioxide results in increased expression of JUN protein
CTD PMID:19408242, PMID:19434695 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G KRAS KRAS proto-oncogene, GTPase increases expression ISO Sulfur Dioxide results in increased expression of KRAS mRNA; Sulfur Dioxide results in increased expression of KRAS protein CTD PMID:19434695 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor decreases expression
multiple interactions
ISO Sulfur Dioxide results in decreased expression of LHCGR mRNA
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of LHCGR mRNA
CTD PMID:30195209 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] CTD PMID:30503585 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MFN1 mitofusin 1 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN1 protein CTD PMID:27521637 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936
JBrowse link
G MFN2 mitofusin 2 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN2 protein CTD PMID:27521637 NCBI chr 1:11,980,215...12,013,508
Ensembl chr 1:11,980,181...12,015,211
Ensembl chr 1:11,980,181...12,015,211
JBrowse link
G MIR1224 microRNA 1224 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR1224 mRNA CTD PMID:31268311 NCBI chr 3:184,241,405...184,241,489
Ensembl chr 3:184,241,405...184,241,489
JBrowse link
G MIR1249 microRNA 1249 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR1249 mRNA CTD PMID:30090456 NCBI chr22:45,200,954...45,201,019
Ensembl chr22:45,200,954...45,201,019
JBrowse link
G MIR125A microRNA 125a multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR125A mRNA CTD PMID:31268311 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339
JBrowse link
G MIR1468 microRNA 1468 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR1468 mRNA CTD PMID:31268311 NCBI chr  X:63,786,002...63,786,087
Ensembl chr  X:63,786,002...63,786,087
JBrowse link
G MIR146B microRNA 146b multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR146B mRNA CTD PMID:31268311 NCBI chr10:102,436,512...102,436,584
Ensembl chr10:102,436,512...102,436,584
JBrowse link
G MIR155 microRNA 155 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR155 mRNA CTD PMID:31268311 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR185 microRNA 185 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR185 mRNA CTD PMID:30090456 NCBI chr22:20,033,139...20,033,220
Ensembl chr22:20,033,139...20,033,220
JBrowse link
G MIR186 microRNA 186 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR186 mRNA CTD PMID:31268311 NCBI chr 1:71,067,631...71,067,716
Ensembl chr 1:71,067,631...71,067,716
JBrowse link
G MIR197 microRNA 197 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR197 mRNA CTD PMID:31268311 NCBI chr 1:109,598,893...109,598,967
Ensembl chr 1:109,598,893...109,598,967
JBrowse link
G MIR205 microRNA 205 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR205 mRNA CTD PMID:30090456 NCBI chr 1:209,432,133...209,432,242
Ensembl chr 1:209,432,133...209,432,242
JBrowse link
G MIR21 microRNA 21 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR21 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR21 mRNA CTD PMID:31268311 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MIR210 microRNA 210 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR210 mRNA CTD PMID:31268311 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198
JBrowse link
G MIR23C microRNA 23c multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR23C mRNA CTD PMID:31268311 NCBI chr  X:20,017,088...20,017,187
Ensembl chr  X:20,017,088...20,017,187
JBrowse link
G MIR2861 microRNA 2861 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR2861 mRNA CTD PMID:31268311 NCBI chr 9:127,785,918...127,786,007
Ensembl chr 9:127,785,918...127,786,007
JBrowse link
G MIR30A microRNA 30a multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR30A mRNA CTD PMID:31268311 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621
JBrowse link
G MIR30E microRNA 30e multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR30E mRNA CTD PMID:30090456 NCBI chr 1:40,754,355...40,754,446
Ensembl chr 1:40,754,355...40,754,446
JBrowse link
G MIR320A microRNA 320a multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR320A mRNA CTD PMID:31268311 NCBI chr 8:22,244,966...22,245,037
Ensembl chr 8:22,244,962...22,245,043
JBrowse link
G MIR338 microRNA 338 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR338 mRNA CTD PMID:30090456 NCBI chr17:81,125,883...81,125,949
Ensembl chr17:81,125,883...81,125,949
JBrowse link
G MIR342 microRNA 342 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR342 mRNA CTD PMID:31268311 NCBI chr14:100,109,655...100,109,753
Ensembl chr14:100,109,655...100,109,753
JBrowse link
G MIR34B microRNA 34b multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR34B mRNA CTD PMID:30090456 NCBI chr11:111,512,938...111,513,021
Ensembl chr11:111,512,938...111,513,021
JBrowse link
G MIR3654 microRNA 3654 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR3654 mRNA CTD PMID:31268311 NCBI chr 7:133,034,860...133,034,915
Ensembl chr 7:133,034,860...133,034,915
JBrowse link
G MIR374B microRNA 374b multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR374B mRNA CTD PMID:31268311 NCBI chr  X:74,218,547...74,218,618
Ensembl chr  X:74,218,547...74,218,618
JBrowse link
G MIR374C microRNA 374c multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR374C mRNA CTD PMID:30090456 NCBI chr  X:74,218,549...74,218,618
Ensembl chr  X:74,218,549...74,218,618
JBrowse link
G MIR375 microRNA 375 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR375 mRNA CTD PMID:30090456 NCBI chr 2:219,001,645...219,001,708
Ensembl chr 2:219,001,645...219,001,708
JBrowse link
G MIR425 microRNA 425 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR425 mRNA CTD PMID:30090456 NCBI chr 3:49,020,148...49,020,234
Ensembl chr 3:49,020,148...49,020,234
JBrowse link
G MIR450B microRNA 450b multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR450B mRNA CTD PMID:30090456 NCBI chr  X:134,540,185...134,540,262
Ensembl chr  X:134,540,185...134,540,262
JBrowse link
G MIR466 microRNA 466 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR466 mRNA CTD PMID:31268311 NCBI chr 3:31,161,704...31,161,787
Ensembl chr 3:31,161,704...31,161,787
JBrowse link
G MIR483 microRNA 483 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR483 mRNA CTD PMID:31268311 NCBI chr11:2,134,134...2,134,209
Ensembl chr11:2,134,134...2,134,209
JBrowse link
G MIR502 microRNA 502 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR500 mRNA CTD PMID:30090456 NCBI chr  X:50,014,598...50,014,683
Ensembl chr  X:50,014,598...50,014,683
JBrowse link
G MIR503 microRNA 503 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR503 mRNA CTD PMID:31268311 NCBI chr  X:134,546,328...134,546,398
Ensembl chr  X:134,546,328...134,546,398
JBrowse link
G MIR504 microRNA 504 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR504 mRNA CTD PMID:30090456 NCBI chr  X:138,667,711...138,667,793
Ensembl chr  X:138,667,711...138,667,793
JBrowse link
G MIR615 microRNA 615 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR615 mRNA CTD PMID:31268311 NCBI chr12:54,033,950...54,034,045
Ensembl chr12:54,033,950...54,034,045
JBrowse link
G MIR6722 microRNA 6722 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR6722 mRNA CTD PMID:31268311 NCBI chr 9:136,746,893...136,746,970
Ensembl chr 9:136,746,893...136,746,970
JBrowse link
G MIR93 microRNA 93 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR93 mRNA CTD PMID:31268311 NCBI chr 7:100,093,768...100,093,847
Ensembl chr 7:100,093,768...100,093,847
JBrowse link
G MIRLET7E microRNA let-7e multiple interactions EXP
ISO
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIRLET7E mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIRLET7E mRNA
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIRLET7E mRNA
CTD PMID:30090456, PMID:31268311 NCBI chr19:51,692,786...51,692,864
Ensembl chr19:51,692,786...51,692,864
JBrowse link
G MIRLET7I microRNA let-7i multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIRLET7I mRNA CTD PMID:31268311 NCBI chr12:62,603,686...62,603,769
Ensembl chr12:62,603,686...62,603,769
JBrowse link
G MPO myeloperoxidase multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein] CTD PMID:30503585 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of ATP6 mRNA
Sulfur Dioxide results in decreased expression of ATP6 mRNA
CTD PMID:22677886, PMID:26980303 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207
JBrowse link
G MT-ATP8 mitochondrially encoded ATP synthase membrane subunit 8 increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of ATP8 mRNA
Sulfur Dioxide results in decreased expression of ATP8 mRNA
CTD PMID:22677886, PMID:26980303 NCBI chr MT:8,366...8,572
Ensembl chr MT:8,366...8,572
JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of COX1 mRNA
Sulfur Dioxide results in decreased expression of COX1 mRNA
CTD PMID:22677886, PMID:26980303 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445
JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO Sulfur Dioxide results in decreased expression of COX2 mRNA CTD PMID:26980303 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269
JBrowse link
G MT-CO3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Sulfur Dioxide results in decreased expression of COX3 mRNA CTD PMID:26980303 NCBI chr MT:9,207...9,990
Ensembl chr MT:9,207...9,990
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC protein]
Sulfur Dioxide results in increased expression of MYC mRNA; Sulfur Dioxide results in increased expression of MYC protein
CTD PMID:19408242, PMID:19434695, PMID:20064080 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MYD88 mRNA CTD PMID:31268311 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,478...38,143,022
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of NOS2 mRNA; Sulfur Dioxide results in increased expression of NOS2 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
CTD PMID:20083630, PMID:30503585 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of NOS3 protein CTD PMID:30090456 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NRF1 nuclear respiratory factor 1 increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of NRF1 protein
Sulfur Dioxide results in decreased expression of NRF1 mRNA; Sulfur Dioxide results in decreased expression of NRF1 protein
CTD PMID:22677886, PMID:26980303 NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of OPA1 protein CTD PMID:27521637 NCBI chr 3:193,593,149...193,697,811
Ensembl chr 3:193,593,144...193,697,811
JBrowse link
G PLA2G7 phospholipase A2 group VII affects expression EXP Sulfur Dioxide affects the expression of PLA2G7 CTD PMID:21356620 NCBI chr 6:46,700,558...46,735,836
Ensembl chr 6:46,704,201...46,735,693
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
decreases expression
ISO glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha decreases expression ISO Sulfur Dioxide results in decreased expression of PPARGC1A mRNA; Sulfur Dioxide results in decreased expression of PPARGC1A protein CTD PMID:26980303 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PRG2 proteoglycan 2, pro eosinophil major basic protein multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of PRG2 mRNA CTD PMID:29621558 NCBI chr11:57,386,780...57,390,650
Ensembl chr11:57,386,780...57,390,650
JBrowse link
G PTGER2 prostaglandin E receptor 2 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of PTGER2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER2 protein]
CTD PMID:21873648 NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,328,598
JBrowse link
G PTGER4 prostaglandin E receptor 4 multiple interactions
increases expression
ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER4 protein] CTD PMID:21873648 NCBI chr 5:40,679,915...40,740,936
Ensembl chr 5:40,679,915...40,693,735
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
Sulfur Dioxide results in increased expression of PTGS2 mRNA; Sulfur Dioxide results in increased expression of PTGS2 protein
CTD PMID:20083630, PMID:21873648, PMID:26209559 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G RB1 RB transcriptional corepressor 1 multiple interactions
decreases expression
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 protein]
Sulfur Dioxide results in decreased expression of RB1 mRNA; Sulfur Dioxide results in decreased expression of RB1 protein
Sulfur Dioxide results in increased expression of RB1 protein
CTD PMID:19408242, PMID:19434695, PMID:20064080 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G SHBG sex hormone binding globulin multiple interactions ISO [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of SHBG mRNA CTD PMID:30195209 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
increases activity
ISO Sulfur Dioxide inhibits the reaction [Alloxan results in decreased activity of SOD1 protein]
Sulfur Dioxide results in increased activity of SOD1 protein
CTD PMID:10871429 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP [[Air Pollutants results in increased abundance of Sulfur Dioxide] which affects the methylation of SOD2 promoter] which affects the methylation of SOD2 promoter CTD PMID:31220783 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOSTDC1 sclerostin domain containing 1 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of SOSTDC1 mRNA CTD PMID:29621558 NCBI chr 7:16,461,481...16,465,738
Ensembl chr 7:16,461,481...16,530,580
JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions ISO [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of STAR mRNA CTD PMID:30195209 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G SYP synaptophysin affects expression ISO Sulfur Dioxide affects the expression of SYP protein CTD PMID:25534910 NCBI chr  X:49,187,815...49,200,193
Ensembl chr  X:49,187,815...49,200,199
Ensembl chr  X:49,187,815...49,200,199
JBrowse link
G TFAM transcription factor A, mitochondrial increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of TFAM mRNA
Sulfur Dioxide results in decreased expression of TFAM mRNA; Sulfur Dioxide results in decreased expression of TFAM protein
CTD PMID:22677886, PMID:26980303 NCBI chr10:58,385,409...58,399,220
Ensembl chr10:58,385,345...58,399,220
JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression ISO Sulfur Dioxide results in increased expression of TGFB1 protein CTD PMID:27565714 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TLR2 toll like receptor 2 multiple interactions EXP [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of TLR2 mRNA CTD PMID:31268311 NCBI chr 4:153,684,080...153,710,643
Ensembl chr 4:153,684,070...153,706,260
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO
EXP
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of TNF protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of TNF protein
CTD PMID:30503585, PMID:31268311 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFSF4 TNF superfamily member 4 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of TNFSF4 mRNA CTD PMID:29621558 NCBI chr 1:173,183,729...173,462,208
Ensembl chr 1:173,183,731...173,207,331
JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 protein; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of TRP53 protein
Sulfur Dioxide results in increased expression of TP53 mRNA; Sulfur Dioxide results in increased expression of TP53 protein
CTD PMID:19408242, PMID:19434695, PMID:20064080, PMID:27521637, PMID:30503585 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA] CTD PMID:30503585 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24359
    role 24266
      application 23758
        food additive 16073
          food bleaching agent 135
            sulfur dioxide 135
Path 2
Term Annotations click to browse term
  CHEBI ontology 24359
    role 24266
      biological role 24233
        physiological role 24177
          food component 24177
            food additive 16073
              food bleaching agent 135
                sulfur dioxide 135
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.