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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:food bleaching agent
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Accession:CHEBI:78003 term browser browse the term
Definition:A food additive that is used for the purpose of decolourising food.
Synonyms:related_synonym: food bleaching agents



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sulfur dioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of AGR2 mRNA CTD PMID:29621558 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of AHR mRNA CTD PMID:32248990 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein decreases expression EXP Sulfur Dioxide results in decreased expression of ARC mRNA CTD PMID:25534910 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Areg amphiregulin multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of AREG mRNA CTD PMID:29621558 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of BAX protein; [Sulfur Dioxide co-treated with sodium arsenite] results in increased expression of BAX mRNA CTD PMID:27521637 PMID:30195209 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of BCL2 mRNA
Sulfur Dioxide results in decreased expression of BCL2 mRNA
CTD PMID:30195209 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Becn1 beclin 1 multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] CTD PMID:30503585 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression EXP Sulfur Dioxide results in decreased expression of CAMK2A protein modified form CTD PMID:25534910 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Capn1 calpain 1 multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] CTD PMID:30503585 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Casp1 caspase 1 multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form] CTD PMID:30503585 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp12 caspase 12 multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
increases expression
EXP
ISO
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein; Sulfur Dioxide results in increased expression of and results in increased activity of CASP3 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP3 mRNA
Sulfur Dioxide results in decreased activity of CASP3 protein
[Sulfur Dioxide co-treated with sodium arsenite] results in increased activity of CASP3 protein; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein
Sulfur Dioxide results in increased expression of CASP3 mRNA
CTD PMID:19621461 PMID:21873648 PMID:26209559 PMID:30195209 PMID:30503585 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
EXP
ISO
Sulfur Dioxide results in increased expression of CASP8 mRNA
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP8 protein
CTD PMID:19621461 PMID:30503585 PMID:31268311 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
EXP
ISO
Sulfur Dioxide results in increased expression of CASP9 mRNA
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP9 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of CASP9 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP9 protein
CTD PMID:19621461 PMID:30503585 PMID:31268311 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP Sulfur Dioxide results in decreased activity of CAT protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA]
CTD PMID:10871429 PMID:30503585 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of CCL1 mRNA CTD PMID:29621558 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
EXP Sulfur Dioxide results in increased expression of CCL2 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]
CTD PMID:27565714 PMID:30503585 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression EXP Sulfur Dioxide results in decreased expression of CCL20 protein CTD PMID:27565714 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases expression
ISO [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CDH2 protein
Sulfur Dioxide results in decreased expression of CDH2 protein
CTD PMID:27237588 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
decreases expression
increases expression
EXP [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A protein]
Sulfur Dioxide results in decreased expression of CDKN2A mRNA; Sulfur Dioxide results in decreased expression of CDKN2A protein
Sulfur Dioxide results in increased expression of CDKN2A protein
CTD PMID:19408242 PMID:19434695 PMID:20064080 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Clca1 chloride channel accessory 1 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CLCA1 mRNA CTD PMID:29621558 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
JBrowse link
G Cldn11 claudin 11 decreases expression
multiple interactions
ISO Sulfur Dioxide results in decreased expression of CLDN11 protein
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CLDN11 protein
CTD PMID:27237588 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Col11a1 collagen type XI alpha 1 chain multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of COL11A1 mRNA CTD PMID:29621558 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression EXP Sulfur Dioxide results in increased expression of COX4I1 mRNA CTD PMID:22677886 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Ctnna1 catenin alpha 1 multiple interactions
decreases expression
ISO [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CTNNA1 protein
Sulfur Dioxide results in decreased expression of CTNNA1 protein
CTD PMID:27237588 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Sulfur Dioxide results in increased expression of CXCL1 protein CTD PMID:27565714 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CXCL11 mRNA CTD PMID:29621558 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein] CTD PMID:30503585 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
decreases expression
EXP Sulfur Dioxide results in decreased activity of CYP1A1 protein
Sulfur Dioxide results in decreased expression of CYP1A1 mRNA
CTD PMID:16023800 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
decreases expression
EXP Sulfur Dioxide results in decreased activity of CYP1A2 protein
Sulfur Dioxide results in decreased expression of CYP1A2 mRNA
CTD PMID:16023800 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of DDIT3 mRNA CTD PMID:31268311 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects expression EXP Sulfur Dioxide affects the expression of DLG4 protein CTD PMID:25534910 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of DNM1L protein CTD PMID:27521637 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dsg2 desmoglein 2 multiple interactions
decreases expression
ISO [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 mRNA; [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 protein
Sulfur Dioxide results in decreased expression of DSG2 mRNA; Sulfur Dioxide results in decreased expression of DSG2 protein
CTD PMID:27237588 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of DUSP1 mRNA CTD PMID:32248990 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Edn1 endothelin 1 increases expression
multiple interactions
EXP
ISO
Sulfur Dioxide results in increased expression of EDN1 mRNA; Sulfur Dioxide results in increased expression of EDN1 protein
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of EDN1 protein
CTD PMID:20083630 PMID:30090456 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of FIS1 protein CTD PMID:27521637 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS protein
Sulfur Dioxide results in increased expression of FOS mRNA; Sulfur Dioxide results in increased expression of FOS protein
CTD PMID:19408242 PMID:19434695 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of GEMIN4 mRNA CTD PMID:32248990 NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression
multiple interactions
ISO Sulfur Dioxide results in decreased expression of GJA1 protein
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of GJA1 protein
CTD PMID:27237588 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] CTD PMID:30503585 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA] CTD PMID:30503585 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of GPX1 mRNA CTD PMID:32248990 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Sulfur Dioxide results in decreased expression of GRIA1 mRNA CTD PMID:25534910 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Sulfur Dioxide results in decreased expression of GRIA2 mRNA CTD PMID:25534910 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression EXP Sulfur Dioxide results in decreased expression of GRIN1 mRNA CTD PMID:25534910 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP Sulfur Dioxide results in decreased expression of GRIN2A mRNA CTD PMID:25534910 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
decreases expression
increases cleavage
EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased cleavage of GRIN2B protein]
Sulfur Dioxide results in decreased expression of GRIN2B mRNA
CTD PMID:21873648 PMID:25534910 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein] CTD PMID:30503585 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases expression
EXP [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS protein]
Sulfur Dioxide results in increased expression of HRAS mRNA; Sulfur Dioxide results in increased expression of HRAS protein
CTD PMID:19408242 PMID:20064080 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP
ISO
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of HSPA5 mRNA
CTD PMID:30503585 PMID:31268311 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions
EXP Sulfur Dioxide results in increased expression of ICAM1 mRNA; Sulfur Dioxide results in increased expression of ICAM1 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
CTD PMID:20083630 PMID:30503585 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
EXP
ISO
Sulfur Dioxide results in increased expression of IFNG protein
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IFNG protein
CTD PMID:27565714 PMID:29621558 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of IKBKB mRNA CTD PMID:31268311 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 increases expression EXP Sulfur Dioxide results in increased expression of IL10 protein CTD PMID:27565714 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IL13 mRNA CTD PMID:29621558 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il17a interleukin 17A multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL17A protein CTD PMID:29621558 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 increases expression EXP Sulfur Dioxide results in increased expression of IL18 protein CTD PMID:27565714 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP Sulfur Dioxide results in increased expression of IL1B protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
CTD PMID:27565714 PMID:30503585 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression EXP Sulfur Dioxide results in increased expression of IL2 protein CTD PMID:27565714 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL4 protein CTD PMID:29621558 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Sulfur Dioxide results in increased expression of IL6 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of IL6 protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of IL6 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]
CTD PMID:20056584 PMID:27565714 PMID:30503585 PMID:31268311 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN protein
Sulfur Dioxide results in increased expression of JUN mRNA; Sulfur Dioxide results in increased expression of JUN protein
CTD PMID:19408242 PMID:19434695 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Klf2 Kruppel-like factor 2 multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of KLF2 mRNA CTD PMID:32248990 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP Sulfur Dioxide results in increased expression of KRAS mRNA; Sulfur Dioxide results in increased expression of KRAS protein CTD PMID:19434695 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions
decreases expression
ISO [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of LHCGR mRNA
Sulfur Dioxide results in decreased expression of LHCGR mRNA
CTD PMID:30195209 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] CTD PMID:30503585 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN1 protein CTD PMID:27521637 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN2 protein CTD PMID:27521637 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mir1224 microRNA 1224 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR1224 mRNA CTD PMID:31268311 NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986
JBrowse link
G Mir1249 microRNA 1249 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR1249 mRNA CTD PMID:30090456 NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712
JBrowse link
G Mir125a microRNA 125a multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR125A mRNA CTD PMID:31268311 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Mir146b microRNA 146b multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR146B mRNA CTD PMID:31268311 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir155 microRNA 155 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR155 mRNA CTD PMID:31268311 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir185 microRNA 185 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR185 mRNA CTD PMID:30090456 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir186 microRNA 186 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR186 mRNA CTD PMID:31268311 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
JBrowse link
G Mir205 microRNA 205 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR205 mRNA CTD PMID:30090456 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
JBrowse link
G Mir21 microRNA 21 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR21 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR21 mRNA CTD PMID:31268311 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir210 microRNA 210 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR210 mRNA CTD PMID:31268311 NCBI chr 1:196,326,343...196,326,452 JBrowse link
G Mir30a microRNA 30a multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR30A mRNA CTD PMID:31268311 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mir30e microRNA 30e multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR30E mRNA CTD PMID:30090456 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
JBrowse link
G Mir320a microRNA 320a multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR320A mRNA CTD PMID:31268311 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir342 microRNA 342 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR342 mRNA CTD PMID:31268311 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mir34b microRNA 34b multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR34B mRNA CTD PMID:30090456 NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327
JBrowse link
G Mir374b microRNA 374b multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR374B mRNA CTD PMID:31268311 NCBI chr  X:68,591,732...68,591,799
Ensembl chr  X:68,591,732...68,591,799
JBrowse link
G Mir375 microRNA 375 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR375 mRNA CTD PMID:30090456 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985
JBrowse link
G Mir425 microRNA 425 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR425 mRNA CTD PMID:30090456 NCBI chr 8:109,264,555...109,264,637
Ensembl chr 8:109,264,555...109,264,637
JBrowse link
G Mir500 microRNA 500 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR500 mRNA CTD PMID:30090456 NCBI chr  X:15,258,778...15,258,857
Ensembl chr  X:15,258,768...15,258,859
JBrowse link
G Mir503 microRNA 503 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR503 mRNA CTD PMID:31268311 NCBI chr  X:132,806,303...132,806,373 JBrowse link
G Mir615 microRNA 615 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR615 mRNA CTD PMID:31268311 NCBI chr 7:134,151,887...134,151,978
Ensembl chr 7:134,151,887...134,151,978
JBrowse link
G Mir93 microRNA 93 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR93 mRNA CTD PMID:31268311 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Mirlet7i microRNA let-7i multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIRLET7I mRNA CTD PMID:31268311 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein] CTD PMID:30503585 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 increases expression
decreases expression
EXP Sulfur Dioxide results in increased expression of ATP6 mRNA
Sulfur Dioxide results in decreased expression of ATP6 mRNA
CTD PMID:22677886 PMID:26980303 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 increases expression
decreases expression
EXP Sulfur Dioxide results in increased expression of ATP8 mRNA
Sulfur Dioxide results in decreased expression of ATP8 mRNA
CTD PMID:22677886 PMID:26980303 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression
decreases expression
EXP Sulfur Dioxide results in increased expression of COX1 mRNA
Sulfur Dioxide results in decreased expression of COX1 mRNA
CTD PMID:22677886 PMID:26980303 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression EXP Sulfur Dioxide results in decreased expression of COX2 mRNA CTD PMID:26980303 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression EXP Sulfur Dioxide results in decreased expression of COX3 mRNA CTD PMID:26980303 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
EXP [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC protein]
Sulfur Dioxide results in increased expression of MYC mRNA; Sulfur Dioxide results in increased expression of MYC protein
CTD PMID:19408242 PMID:19434695 PMID:20064080 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MYD88 mRNA CTD PMID:31268311 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
EXP Sulfur Dioxide results in increased expression of NOS2 mRNA; Sulfur Dioxide results in increased expression of NOS2 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
CTD PMID:20083630 PMID:30503585 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of NOS3 protein CTD PMID:30090456 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression
decreases expression
EXP Sulfur Dioxide results in increased expression of NRF1 protein
Sulfur Dioxide results in decreased expression of NRF1 mRNA; Sulfur Dioxide results in decreased expression of NRF1 protein
CTD PMID:22677886 PMID:26980303 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of OPA1 protein CTD PMID:27521637 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Pla2g7 phospholipase A2 group VII affects expression ISO Sulfur Dioxide affects the expression of PLA2G7 CTD PMID:21356620 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
ISO glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression EXP Sulfur Dioxide results in decreased expression of PPARGC1A mRNA; Sulfur Dioxide results in decreased expression of PPARGC1A protein CTD PMID:26980303 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prg2 proteoglycan 2 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of PRG2 mRNA CTD PMID:29621558 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101
JBrowse link
G Ptger2 prostaglandin E receptor 2 increases expression
multiple interactions
EXP Sulfur Dioxide results in increased expression of PTGER2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER2 protein]
CTD PMID:21873648 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions
increases expression
EXP N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER4 protein] CTD PMID:21873648 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP
ISO
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]
[Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of PTGS2 mRNA
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
Sulfur Dioxide results in increased expression of PTGS2 mRNA; Sulfur Dioxide results in increased expression of PTGS2 protein
CTD PMID:20083630 PMID:21873648 PMID:26209559 PMID:32248990 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases expression
increases expression
EXP [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 protein]
Sulfur Dioxide results in decreased expression of RB1 mRNA; Sulfur Dioxide results in decreased expression of RB1 protein
Sulfur Dioxide results in increased expression of RB1 protein
CTD PMID:19408242 PMID:19434695 PMID:20064080 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Shbg sex hormone binding globulin multiple interactions ISO [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of SHBG mRNA CTD PMID:30195209 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases activity
EXP Sulfur Dioxide inhibits the reaction [Alloxan results in decreased activity of SOD1 protein]
Sulfur Dioxide results in increased activity of SOD1 protein
CTD PMID:10871429 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [[Air Pollutants results in increased abundance of Sulfur Dioxide] which affects the methylation of SOD2 promoter] which affects the methylation of SOD2 promoter CTD PMID:31220783 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sostdc1 sclerostin domain containing 1 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of SOSTDC1 mRNA CTD PMID:29621558 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of STAR mRNA CTD PMID:30195209 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Syp synaptophysin affects expression EXP Sulfur Dioxide affects the expression of SYP protein CTD PMID:25534910 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression
decreases expression
EXP Sulfur Dioxide results in increased expression of TFAM mRNA
Sulfur Dioxide results in decreased expression of TFAM mRNA; Sulfur Dioxide results in decreased expression of TFAM protein
CTD PMID:22677886 PMID:26980303 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Sulfur Dioxide results in increased expression of TGFB1 protein CTD PMID:27565714 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of TLR2 mRNA CTD PMID:31268311 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of TLR4 mRNA CTD PMID:32248990 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of TNF protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of TNF protein; [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of TNF mRNA; TNF gene SNP affects the susceptibility to [[Air Pollutants results in increased abundance of Fuel Oils] which results in increased abundance of Sulfur Dioxide]
CTD PMID:24056475 PMID:30503585 PMID:31268311 PMID:32248990 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of TNFRSF1B mRNA CTD PMID:32248990 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfsf4 TNF superfamily member 4 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of TNFSF4 mRNA CTD PMID:29621558 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
EXP
ISO
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 protein; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of TRP53 protein
Sulfur Dioxide results in increased expression of TP53 mRNA; Sulfur Dioxide results in increased expression of TP53 protein
CTD PMID:19408242 PMID:19434695 PMID:20064080 PMID:27521637 PMID:30503585 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of TXNRD1 mRNA CTD PMID:32248990 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA] CTD PMID:30503585 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO [Air Pollutants results in increased abundance of Sulfur Dioxide] which results in decreased expression of XBP1 mRNA CTD PMID:32248990 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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  CHEBI ontology 19823
    role 19773
      application 19486
        food additive 15113
          food bleaching agent 131
            sulfur dioxide 131
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      biological role 19773
        physiological role 19771
          food component 19771
            food additive 15113
              food bleaching agent 131
                sulfur dioxide 131
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