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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oripavine
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Accession:CHEBI:7782 term browser browse the term
Definition:A morphinane alkaloid with formula C18H19NO3. It is the major metabolite of thebaine.
Synonyms:exact_synonym: 6-methoxy-17-methyl-5alpha-6,7,8,14-tetradehydro-4,5-epoxymorphinan-3-ol
 related_synonym: (5alpha)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol;   3-O-demethylthebaine;   6,7,8,14-tetradehydro-4,5alpha-epoxy-6-methoxy-17-methyl-morphinan-3-ol;   Formula=C18H19NO3;   InChI=1S/C18H19NO3/c1-19-8-7-18-11-4-6-14(21-2)17(18)22-16-13(20)5-3-10(15(16)18)9-12(11)19/h3-6,12,17,20H,7-9H2,1-2H3/t12-,17+,18+/m1/s1;   InChIKey=ZKLXUUYLEHCAMF-UUWFMWQGSA-N;   SMILES=COC1=CC=C2[C@H]3CC4=CC=C(O)C5=C4[C@@]2(CCN3C)[C@H]1O5
 xref: CAS:467-04-9;   FooDB:FDB002075;   HMDB:HMDB0030251;   KEGG:C06175;   KNApSAcK:C00028775;   PMID:1177252;   PMID:16135;   PMID:17912784;   PMID:21186398;   PMID:21495679;   PMID:28095631;   PMID:37132502;   Patent:AU2008203048;   Patent:AU2008231127;   Patent:US2010113787;   Wikipedia:Oripavine
 cyclic_relationship: is_conjugate_base_of CHEBI:194499



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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 increases expression EXP Oxycodone results in increased expression of ABCA8 mRNA CTD PMID:23439660 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP Oxycodone results in increased expression of ABCB1A mRNA; Oxycodone results in increased expression of ABCB1A protein CTD PMID:23439660 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Oxycodone results in increased expression of ABCB4 mRNA CTD PMID:23439660 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression EXP Oxycodone results in decreased expression of ABCG1 mRNA CTD PMID:23439660 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Oxycodone results in increased expression of ABCG5 mRNA CTD PMID:23439660 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase increases expression EXP Oxycodone results in increased expression of ABHD6 mRNA CTD PMID:23439660 NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 increases expression EXP Oxycodone results in increased expression of ACSM2A mRNA CTD PMID:23439660 NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116
JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP Oxycodone results in decreased expression of ACTN1 mRNA CTD PMID:23439660 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 decreases expression EXP Oxycodone results in decreased expression of ADAM17 mRNA CTD PMID:23439660 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression EXP Oxycodone results in increased expression of ADAMTS1 mRNA CTD PMID:23439660 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 decreases expression EXP Oxycodone results in decreased expression of ADGRE1 mRNA CTD PMID:23439660 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression EXP Oxycodone results in increased expression of AHR mRNA CTD PMID:23439660 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases expression EXP Oxycodone results in decreased expression of AKR1C3 mRNA CTD PMID:23439660 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression EXP
ISO
Oxycodone increases expression of Akt1 mRNA in the hippocampal formation
Oxycodone increases expression of Akt1 mRNA in the hippocampus
RGD PMID:31071414 PMID:25446355 RGD:405866388, RGD:407445976 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Oxycodone results in decreased expression of ANXA3 mRNA CTD PMID:23439660 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression EXP Oxycodone results in decreased expression of ARHGDIB mRNA CTD PMID:23439660 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Asl argininosuccinate lyase increases expression EXP Oxycodone results in increased expression of ASL mRNA CTD PMID:23439660 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO
EXP
Oxycodone results in increased expression of ATF4 protein CTD PMID:26377394 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Oxycodone results in increased expression of ATP1B1 mRNA CTD PMID:23439660 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 increases expression EXP Oxycodone results in increased expression of B4GALNT1 mRNA CTD PMID:23439660 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression EXP Oxycodone results in decreased expression of BCL2A1 mRNA CTD PMID:23439660 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Blvra biliverdin reductase A decreases expression EXP Oxycodone results in decreased expression of BLVRA mRNA CTD PMID:23439660 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
JBrowse link
G Car3 carbonic anhydrase 3 decreases expression EXP Oxycodone results in decreased expression of CA3 mRNA CTD PMID:23439660 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Cav2 caveolin 2 decreases expression EXP Oxycodone results in decreased expression of CAV2 mRNA CTD PMID:23439660 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 decreases expression EXP Oxycodone results in decreased expression of CCL6 mRNA CTD PMID:23439660 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Cd5l Cd5 molecule-like decreases expression EXP Oxycodone results in decreased expression of CD5L mRNA CTD PMID:23439660 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Oxycodone results in increased expression of CDKN1A mRNA CTD PMID:23439660 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ces2h carboxylesterase 2H affects expression
increases expression
EXP Oxycodone affects the expression of CES2 mRNA
Oxycodone results in increased expression of CES2 mRNA
CTD PMID:20487198 PMID:23439660 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression EXP Oxycodone results in increased expression of CHD1L mRNA CTD PMID:23439660 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 decreases expression EXP Oxycodone results in decreased expression of CMTM6 mRNA CTD PMID:23439660 NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression EXP Oxycodone results in decreased expression of CNP1 mRNA CTD PMID:23439660 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression EXP Oxycodone results in decreased expression of COTL1 mRNA CTD PMID:23439660 NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP Oxycodone results in decreased expression of CSRP1 mRNA CTD PMID:23439660 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Ctsc cathepsin C decreases expression EXP Oxycodone results in decreased expression of CTSC mRNA CTD PMID:23439660 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctsl cathepsin L increases expression EXP Oxycodone results in increased expression of CTSL mRNA CTD PMID:23439660 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression EXP Oxycodone results in decreased expression of CYBA mRNA CTD PMID:23439660 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression
increases expression
EXP Oxycodone affects the expression of CYP17A1 mRNA
Oxycodone results in increased expression of CYP17A1 mRNA
CTD PMID:20487198 PMID:23439660 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP27A1 mRNA CTD PMID:23439660 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP2A1 mRNA CTD PMID:23439660 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression
increases expression
EXP Oxycodone affects the expression of CYP2B2 mRNA
Oxycodone results in increased expression of CYP2B2 mRNA; Oxycodone results in increased expression of CYP2B2 protein
CTD PMID:20487198 PMID:23439660 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP Oxycodone results in decreased expression of CYP2C11 mRNA CTD PMID:23439660 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 affects expression
decreases expression
EXP Oxycodone affects the expression of CYP2C13 mRNA
Oxycodone results in decreased expression of CYP2C13 mRNA
CTD PMID:20487198 PMID:23439660 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 decreases expression EXP Oxycodone results in decreased expression of CYP2C9 mRNA CTD PMID:23439660 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects response to substance
multiple interactions
ISO CYP2D6 gene polymorphism affects the susceptibility to Oxycodone
[Quinidine results in decreased activity of CYP2D6 protein] which affects the susceptibility to Oxycodone
CTD PMID:20590588 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP2E1 mRNA CTD PMID:23439660 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression EXP Oxycodone results in increased expression of CYP2J4 mRNA CTD PMID:23439660 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases expression
affects metabolic processing
EXP
ISO
Oxycodone inhibits the reaction [CYP3A2 protein results in increased hydroxylation of Testosterone]
Oxycodone results in decreased expression of CYP3A2 mRNA; Oxycodone results in decreased expression of CYP3A2 protein
telithromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Oxycodone]
CYP3A4 protein alternative form affects the metabolism of Oxycodone
CTD PMID:19755414 PMID:20487198 PMID:33393779 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP3A23-3A1 mRNA; Oxycodone results in increased expression of CYP3A23-3A1 protein CTD PMID:23439660 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP4B1 mRNA CTD PMID:23439660 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 increases expression EXP Oxycodone results in increased expression of DBT mRNA CTD PMID:23439660 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP Oxycodone results in increased expression of EHHADH mRNA CTD PMID:23439660 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
ISO
EXP
Naloxone inhibits the reaction [Oxycodone results in increased phosphorylation of EIF2S1 protein] CTD PMID:26377394 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 increases expression EXP Oxycodone results in increased expression of ELL2 mRNA CTD PMID:23439660 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Ephx2 epoxide hydrolase 2 affects expression EXP Oxycodone affects the expression of EPHX2 mRNA CTD PMID:20487198 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Exosc5 exosome component 5 increases expression EXP Oxycodone results in increased expression of EXOSC5 mRNA CTD PMID:23439660 NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
JBrowse link
G Fcgr2a Fc gamma receptor 2A decreases expression EXP Oxycodone results in decreased expression of FCGR2A mRNA CTD PMID:23439660 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP Oxycodone results in increased expression of FKBP5 mRNA CTD PMID:23439660 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression
increases expression
EXP Oxycodone affects the expression of FMO1 mRNA
Oxycodone results in increased expression of FMO1 mRNA
CTD PMID:20487198 PMID:23439660 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Oxycodone results in increased expression of FOS protein CTD PMID:26377394 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Oxycodone results in increased expression of GPAM mRNA CTD PMID:23439660 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP Oxycodone results in increased expression of GPT mRNA CTD PMID:23439660 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression EXP Oxycodone results in increased expression of GPT2 mRNA CTD PMID:23439660 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP Oxycodone results in increased expression of GSTA3 mRNA CTD PMID:23439660 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP Oxycodone results in increased expression of GSTA5 mRNA; Oxycodone results in increased expression of GSTA5 protein CTD PMID:20487198 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression EXP Oxycodone results in increased expression of HACL1 mRNA CTD PMID:23439660 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP Oxycodone results in decreased expression of HAO2 mRNA CTD PMID:23439660 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase decreases expression EXP Oxycodone results in decreased expression of HCK mRNA CTD PMID:23439660 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Hexb hexosaminidase subunit beta increases expression EXP Oxycodone results in increased expression of HEXB mRNA CTD PMID:23439660 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B increases expression EXP Oxycodone results in increased expression of HNRNPAB mRNA CTD PMID:23439660 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Oxycodone results in increased expression of HOMER1 mRNA CTD PMID:23439660 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP Oxycodone results in decreased expression of HSD11B1 mRNA CTD PMID:23439660 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO
EXP
Oxycodone results in increased expression of HSPA5 protein CTD PMID:26377394 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP Oxycodone results in decreased expression of IGFALS mRNA CTD PMID:23439660 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP Oxycodone results in increased expression of IGFBP1 mRNA CTD PMID:23439660 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Il18bp interleukin 18 binding protein decreases expression EXP Oxycodone results in decreased expression of IL18BP mRNA CTD PMID:23439660 NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963
JBrowse link
G Inhbe inhibin subunit beta E decreases expression EXP Oxycodone results in decreased expression of INHBE mRNA CTD PMID:23439660 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 increases expression EXP Oxycodone results in increased expression of IP6K2 mRNA CTD PMID:23439660 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression EXP Oxycodone results in decreased expression of ITGB2 mRNA CTD PMID:23439660 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression EXP Oxycodone results in increased expression of ITPR1 mRNA CTD PMID:23439660 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression EXP Oxycodone results in decreased expression of JCHAIN mRNA CTD PMID:23439660 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298
JBrowse link
G Klc4 kinesin light chain 4 increases expression EXP Oxycodone results in increased expression of KLC4 mRNA CTD PMID:23439660 NCBI chr 9:14,337,164...14,351,075
Ensembl chr 9:14,337,534...14,351,066
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 decreases expression EXP Oxycodone results in decreased expression of LCP1 mRNA CTD PMID:23439660 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
JBrowse link
G Lgals3 galectin 3 decreases expression EXP Oxycodone results in decreased expression of LGALS3 mRNA CTD PMID:23439660 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase increases expression EXP Oxycodone results in increased expression of LHPP mRNA CTD PMID:23439660 NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component decreases expression EXP Oxycodone results in decreased expression of LIN7A mRNA CTD PMID:23439660 NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550
JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression EXP Oxycodone results in decreased expression of LY86 mRNA CTD PMID:23439660 NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation EXP Oxycodone results in increased phosphorylation of MAPK1 protein CTD PMID:26377394 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation EXP Oxycodone results in increased phosphorylation of MAPK3 protein CTD PMID:26377394 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Masp1 MBL associated serine protease 1 decreases expression EXP Oxycodone results in decreased expression of MASP1 mRNA CTD PMID:23439660 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
G Mtmr7 myotubularin related protein 7 increases expression EXP Oxycodone results in increased expression of MTMR7 mRNA CTD PMID:23439660 NCBI chr16:51,641,267...51,732,212
Ensembl chr16:51,641,190...51,732,182
JBrowse link
G Myo1b myosin Ib increases expression EXP Oxycodone results in increased expression of MYO1B mRNA CTD PMID:23439660 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
JBrowse link
G Notch2 notch receptor 2 decreases expression EXP Oxycodone results in decreased expression of NOTCH2 mRNA CTD PMID:23439660 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression EXP Oxycodone results in increased expression of NR1I2 mRNA CTD PMID:23439660 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression EXP Oxycodone results in increased expression of NR1I3 mRNA CTD PMID:23439660 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP Oxycodone results in decreased expression of NREP mRNA CTD PMID:23439660 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Oprd1 opioid receptor, delta 1 affects binding EXP Oxycodone binds to OPRD1 protein CTD PMID:7562497 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprk1 opioid receptor, kappa 1 affects binding EXP Oxycodone binds to OPRK1 protein CTD PMID:7562497 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 affects binding EXP Oxycodone binds to OPRM1 protein CTD PMID:7562497 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Orm1 orosomucoid 1 decreases expression EXP Oxycodone results in decreased expression of ORM1 mRNA CTD PMID:23439660 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression EXP Oxycodone results in decreased expression of OSGIN1 mRNA CTD PMID:23439660 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression EXP Oxycodone results in decreased expression of PDE4B mRNA CTD PMID:23439660 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha increases expression EXP Oxycodone results in increased expression of PDGFRA protein CTD PMID:26377394 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression EXP Oxycodone results in increased expression of PFKFB1 mRNA CTD PMID:23439660 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression EXP Oxycodone results in decreased expression of PIK3C3 mRNA CTD PMID:23439660 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pla2g4a phospholipase A2 group 4A decreases expression EXP Oxycodone results in decreased expression of PLA2G4A mRNA CTD PMID:23439660 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pld1 phospholipase D1 decreases expression EXP Oxycodone results in decreased expression of PLD1 mRNA CTD PMID:23439660 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Plscr1 phospholipid scramblase 1 decreases expression EXP Oxycodone results in decreased expression of PLSCR1 mRNA CTD PMID:23439660 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 increases expression EXP Oxycodone results in increased expression of PNPLA7 mRNA CTD PMID:23439660 NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Oxycodone results in increased expression of POR mRNA CTD PMID:23439660 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression EXP Oxycodone results in decreased expression of PRKAB1 mRNA CTD PMID:23439660 NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases phosphorylation EXP Oxycodone results in increased phosphorylation of PRKACA protein CTD PMID:26377394 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prlr prolactin receptor increases expression EXP Oxycodone results in increased expression of PRLR mRNA CTD PMID:23439660 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
JBrowse link
G Ptdss2 phosphatidylserine synthase 2 increases expression EXP Oxycodone results in increased expression of PTDSS2 mRNA CTD PMID:23439660 NCBI chr 1:196,241,439...196,267,632
Ensembl chr 1:196,241,494...196,267,685
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression EXP Oxycodone results in increased expression of PTP4A1 mRNA CTD PMID:23439660 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Pxmp4 peroxisomal membrane protein 4 increases expression EXP Oxycodone results in increased expression of PXMP4 mRNA CTD PMID:23439660 NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651
JBrowse link
G Pycard PYD and CARD domain containing decreases expression EXP Oxycodone results in decreased expression of PYCARD mRNA CTD PMID:23439660 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression EXP Oxycodone results in increased expression of RAB30 mRNA CTD PMID:23439660 NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
JBrowse link
G Rab38 RAB38, member RAS oncogene family decreases expression EXP Oxycodone results in decreased expression of RAB38 mRNA CTD PMID:23439660 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924
JBrowse link
G Rac2 Rac family small GTPase 2 decreases expression EXP Oxycodone results in decreased expression of RAC2 mRNA CTD PMID:23439660 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Rcan1 regulator of calcineurin 1 decreases expression EXP Oxycodone results in decreased expression of RCAN1 mRNA CTD PMID:23439660 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Serpina7 serpin family A member 7 decreases expression EXP Oxycodone results in decreased expression of SERPINA7 mRNA CTD PMID:23439660 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression EXP Oxycodone results in decreased expression of SKAP2 mRNA CTD PMID:23439660 NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:80,950,580...81,100,891
JBrowse link
G Slc10a2 solute carrier family 10 member 2 decreases expression EXP Oxycodone results in decreased expression of SLC10A2 mRNA CTD PMID:23439660 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc15a3 solute carrier family 15 member 3 decreases expression EXP Oxycodone results in decreased expression of SLC15A3 mRNA CTD PMID:23439660 NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157
JBrowse link
G Slc16a1 solute carrier family 16 member 1 decreases expression EXP Oxycodone results in decreased expression of SLC16A1 mRNA CTD PMID:23439660 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP Oxycodone results in increased expression of SLC16A10 mRNA CTD PMID:23439660 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Slc17a5 solute carrier family 17 member 5 increases expression EXP Oxycodone results in increased expression of SLC17A5 mRNA CTD PMID:23439660 NCBI chr 8:79,394,416...79,429,387 JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Oxycodone results in increased expression of SLC1A2 mRNA CTD PMID:23439660 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP Oxycodone results in increased expression of SLC22A5 mRNA CTD PMID:23439660 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases expression EXP Oxycodone results in decreased expression of SLC22A8 mRNA CTD PMID:23439660 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc25a15 solute carrier family 25 member 15 increases expression EXP Oxycodone results in increased expression of SLC25A15 mRNA CTD PMID:23439660 NCBI chr16:69,631,581...69,654,869
Ensembl chr16:69,634,414...69,653,010
JBrowse link
G Slc25a29 solute carrier family 25 member 29 increases expression EXP Oxycodone results in increased expression of SLC25A29 mRNA CTD PMID:23439660 NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940
JBrowse link
G Slc25a30 solute carrier family 25, member 30 decreases expression EXP Oxycodone results in decreased expression of SLC25A30 mRNA CTD PMID:23439660 NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613
JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression EXP Oxycodone results in increased expression of SLC27A5 mRNA CTD PMID:23439660 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression EXP Oxycodone results in increased expression of SLC2A2 mRNA CTD PMID:23439660 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Oxycodone results in decreased expression of SLC34A2 mRNA CTD PMID:23439660 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
JBrowse link
G Slc35b2 solute carrier family 35 member B2 decreases expression EXP Oxycodone results in decreased expression of SLC35B2 mRNA CTD PMID:23439660 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
JBrowse link
G Slc37a4 solute carrier family 37 member 4 increases expression EXP Oxycodone results in increased expression of SLC37A4 mRNA CTD PMID:23439660 NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
JBrowse link
G Slc38a4 solute carrier family 38, member 4 increases expression EXP Oxycodone results in increased expression of SLC38A4 mRNA CTD PMID:23439660 NCBI chr 7:128,142,866...128,203,000
Ensembl chr 7:128,144,807...128,202,995
JBrowse link
G Slc39a4 solute carrier family 39 member 4 increases expression EXP Oxycodone results in increased expression of SLC39A4 mRNA CTD PMID:23439660 NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553
JBrowse link
G Slc41a2 solute carrier family 41 member 2 decreases expression EXP Oxycodone results in decreased expression of SLC41A2 mRNA CTD PMID:23439660 NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166
JBrowse link
G Slc49a4 solute carrier family 49 member 4 increases expression EXP Oxycodone results in increased expression of SLC49A4 mRNA CTD PMID:23439660 NCBI chr11:64,995,629...65,068,929
Ensembl chr11:64,995,679...65,068,926
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression EXP Oxycodone results in decreased expression of SLC6A9 mRNA CTD PMID:23439660 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Slc7a7 solute carrier family 7 member 7 decreases expression EXP Oxycodone results in decreased expression of SLC7A7 mRNA CTD PMID:23439660 NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases expression EXP Oxycodone results in increased expression of SLCO1B2 mRNA CTD PMID:23439660 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression EXP Oxycodone results in decreased expression of SLPI mRNA CTD PMID:23439660 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Smarcd2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 increases expression EXP Oxycodone results in increased expression of SMARCD2 mRNA CTD PMID:23439660 NCBI chr10:91,193,752...91,202,817
Ensembl chr10:91,193,752...91,204,341
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP Oxycodone results in decreased expression of STAC3 mRNA CTD PMID:23439660 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
JBrowse link
G Sulf2 sulfatase 2 increases expression EXP Oxycodone results in increased expression of SULF2 mRNA CTD PMID:23439660 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Sult5a1 sulfotransferase family 5A, member 1 decreases expression EXP Oxycodone results in decreased expression of SULT1A2 mRNA CTD PMID:23439660 NCBI chr19:51,189,287...51,204,275
Ensembl chr19:51,189,287...51,204,362
JBrowse link
G Sycp3 synaptonemal complex protein 3 increases expression EXP Oxycodone results in increased expression of SYCP3 mRNA CTD PMID:23439660 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression EXP Oxycodone results in decreased expression of TARS1 mRNA CTD PMID:23439660 NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Thumpd1 THUMP domain containing 1 decreases expression EXP Oxycodone results in decreased expression of THUMPD1 mRNA CTD PMID:23439660 NCBI chr 1:174,078,875...174,084,915
Ensembl chr 1:174,078,878...174,084,937
JBrowse link
G Timm8a1 translocase of inner mitochondrial membrane 8A1 increases expression EXP Oxycodone results in increased expression of TIMM8A mRNA CTD PMID:23439660 NCBI chr  X:97,717,932...97,722,170
Ensembl chr  X:97,717,920...97,721,960
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor increases expression EXP Oxycodone results in increased expression of TLE1 mRNA CTD PMID:23439660 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
JBrowse link
G Tmem19 transmembrane protein 19 decreases expression EXP Oxycodone results in decreased expression of TMEM19 mRNA CTD PMID:23439660 NCBI chr 7:50,958,884...50,985,601
Ensembl chr 7:50,958,888...50,986,809
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression EXP Oxycodone results in increased expression of TSC22D3 mRNA CTD PMID:23439660 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression EXP Oxycodone results in increased expression of TSKU mRNA CTD PMID:23439660 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP Oxycodone results in decreased expression of TUBB5 mRNA CTD PMID:23439660 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP Oxycodone results in increased expression of UGT1A1 mRNA CTD PMID:23439660 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Usp12 ubiquitin specific peptidase 12 decreases expression EXP Oxycodone results in decreased expression of USP12 mRNA CTD PMID:23439660 NCBI chr12:8,309,845...8,363,686
Ensembl chr12:8,309,750...8,363,656
JBrowse link
G Ust5r integral membrane transport protein UST5r decreases expression EXP Oxycodone results in decreased expression of UST5R mRNA CTD PMID:23439660 NCBI chr 1:205,210,558...205,286,868
Ensembl chr 1:205,211,034...205,286,718
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases expression EXP Oxycodone results in decreased expression of VASP mRNA CTD PMID:23439660 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Vim vimentin decreases expression EXP Oxycodone results in decreased expression of VIM mRNA CTD PMID:23439660 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Zfp354a zinc finger protein 354A increases expression EXP Oxycodone results in increased expression of ZNF354A mRNA CTD PMID:23439660 NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      biological role 19891
        pharmacological role 19122
          analgesic 14785
            opioid analgesic 669
              oripavine 165
                thebaine + 165
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    main group molecular entity 19865
                      s-block molecular entity 19697
                        hydrogen molecular entity 19678
                          hydrides 19184
                            inorganic hydride 18194
                              pnictogen hydride 18184
                                nitrogen hydride 18096
                                  azane 17900
                                    ammonia 17899
                                      organic amino compound 17899
                                        tertiary amino compound 10158
                                          oripavine 165
                                            thebaine + 165
paths to the root