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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:orientin
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Accession:CHEBI:7781 term browser browse the term
Definition:A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.
Synonyms:exact_synonym: 2-(3,4-dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-chromen-4-one
 related_synonym: 8-beta-D-glucosylluteolin;   Formula=C21H20O11;   InChI=1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1;   InChIKey=PLAPMLGJVGLZOV-VPRICQMDSA-N;   Luteolin 8-C-glucoside;   Lutexin;   SMILES=OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)c(O)c1
 xref: CAS:28608-75-5;   HMDB:HMDB0030614;   KEGG:C10114;   KNApSAcK:C00001078;   LIPID_MAPS_instance:LMPK12110470
 xref_mesh: MESH:C065886
 xref: PMID:21283956;   PMID:21417394;   PMID:22994444;   PMID:23107458;   PMID:23358325;   Reaxys:69376;   Wikipedia:Orientin


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orientin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ADIPOQ protein] CTD PMID:32044341 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Insr insulin receptor increases expression ISO orientin results in increased expression of INSR protein CTD PMID:32044341 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IRS1 protein] CTD PMID:32044341 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A protein] CTD PMID:32044341 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARG protein] CTD PMID:32044341 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARGC1A protein] CTD PMID:32044341 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A4 protein] CTD PMID:32044341 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      chemical role 19336
        antioxidant 14442
          orientin 7
            orientin 2''-O-rhamnoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic molecule 19560
                              organic cyclic compound 19351
                                organic heterocyclic compound 18582
                                  oxacycle 17586
                                    benzopyran 10410
                                      1-benzopyran 10136
                                        flavonoid 6516
                                          flavones 4204
                                            hydroxyflavone 4192
                                              3'-hydroxyflavonoid 255
                                                luteolin 199
                                                  orientin 7
                                                    orientin 2''-O-rhamnoside 0
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