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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:orientin
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Accession:CHEBI:7781 term browser browse the term
Definition:A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.
Synonyms:exact_synonym: 2-(3,4-dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-chromen-4-one
 related_synonym: 8-beta-D-glucosylluteolin;   Formula=C21H20O11;   InChI=1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1;   InChIKey=PLAPMLGJVGLZOV-VPRICQMDSA-N;   Luteolin 8-C-glucoside;   Lutexin;   SMILES=OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)c(O)c1
 xref: CAS:28608-75-5;   HMDB:HMDB0030614;   KEGG:C10114;   KNApSAcK:C00001078;   LIPID_MAPS_instance:LMPK12110470
 xref_mesh: MESH:C065886
 xref: PMID:21283956;   PMID:21417394;   PMID:22994444;   PMID:23107458;   PMID:23358325;   Reaxys:69376;   Wikipedia:Orientin


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orientin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ADIPOQ protein] CTD PMID:32044341 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Insr insulin receptor increases expression ISO orientin results in increased expression of INSR protein CTD PMID:32044341 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IRS1 protein] CTD PMID:32044341 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A protein] CTD PMID:32044341 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARG protein] CTD PMID:32044341 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARGC1A protein] CTD PMID:32044341 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO orientin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A4 protein] CTD PMID:32044341 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      chemical role 19248
        antioxidant 14209
          orientin 7
            orientin 2''-O-rhamnoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  oxacycle 17181
                                    benzopyran 10132
                                      1-benzopyran 9848
                                        flavonoid 6372
                                          flavones 4166
                                            hydroxyflavone 4154
                                              3'-hydroxyflavonoid 232
                                                luteolin 171
                                                  orientin 7
                                                    orientin 2''-O-rhamnoside 0
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