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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:S-nitroso-N-acetyl-D-penicillamine
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Accession:CHEBI:77702 term browser browse the term
Definition:A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group.
Synonyms:exact_synonym: N-acetyl-3-(nitrososulfanyl)-D-valine
 related_synonym: Formula=C7H12N2O4S;   InChI=1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1;   InChIKey=ZIIQCSMRQKCOCT-YFKPBYRVSA-N;   N-Acetyl-S-nitrosopenicillamine;   S-Nitrosoacetylpenicillamine;   S-Nonap;   S-nitroso-N-acetylpenicillamine;   SMILES=CC(=O)N[C@@H](C(O)=O)C(C)(C)SN=O;   SNAP
 xref: CAS:79032-48-7
 xref_mesh: MESH:D026423
 xref: PMID:1363990;   PMID:14659604;   PMID:16526748;   PMID:23777908;   PMID:23929591;   PMID:23964741;   PMID:24280957;   PMID:24331454;   PMID:24480299;   PMID:24510762;   Reaxys:6646600;   Wikipedia:S-Nitroso-N-acetylpenicillamine



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S-nitroso-N-acetyl-D-penicillamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO AIFM1 protein inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased reduction of Glutathione]; AIFM1 protein promotes the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased reduction of Adenine Nucleotides] CTD PMID:15316071 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein]]; Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein]; wortmannin promotes the reaction [Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein]] CTD PMID:21138475 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of AQP3 mRNA CTD PMID:12102619 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Bad BCL2-associated agonist of cell death decreases phosphorylation
multiple interactions
ISO S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of BAD protein
Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of BAD protein]
CTD PMID:21138475 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO S-Nitroso-N-Acetylpenicillamine results in increased expression of BAX protein
Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased expression of BAX protein]
CTD PMID:21138475 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of BCL2 protein]
S-Nitroso-N-Acetylpenicillamine results in decreased expression of BCL2 mRNA; S-Nitroso-N-Acetylpenicillamine results in decreased expression of BCL2 protein
CTD PMID:17135264 PMID:21138475 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases secretion
EXP Carbon Dioxide inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased secretion of CALCA protein] CTD PMID:18052948 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased activity of and results in increased cleavage of CASP1 protein CTD PMID:10903723 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
decreases activity
ISO
EXP
[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of CASP3 protein]
S-Nitroso-N-Acetylpenicillamine results in increased activity of CASP3 protein
S-Nitroso-N-Acetylpenicillamine results in decreased activity of CASP3 protein
Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased activity of CASP3 protein]
CTD PMID:10811113 PMID:12006578 PMID:12220328 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO S-Nitroso-N-Acetylpenicillamine inhibits the reaction [3,5-dimethoxy-4'-hydroxystilbene results in decreased phosphorylation of CREB1 protein]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Quercetin results in decreased phosphorylation of CREB1 protein] CTD PMID:17135264 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of CSRP3 mRNA CTD PMID:12102619 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Drgx dorsal root ganglia homeobox decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of PRRXL1 mRNA CTD PMID:12102619 NCBI chr16:7,854,849...7,884,404
Ensembl chr16:7,854,849...7,900,600
JBrowse link
G Edn1 endothelin 1 increases secretion EXP S-Nitroso-N-Acetylpenicillamine results in increased secretion of EDN1 protein CTD PMID:15640287 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eln elastin decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of ELN mRNA CTD PMID:12102619 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Exoc6 exocyst complex component 6 decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of SEC15 mRNA CTD PMID:12102619 NCBI chr 1:235,314,612...235,457,824
Ensembl chr 1:235,300,369...235,457,015
JBrowse link
G Faslg Fas ligand multiple interactions ISO [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter] CTD PMID:10811113 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fcgr2a Fc gamma receptor IIa decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of FCGR3 mRNA CTD PMID:12102619 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fcgr2b Fc gamma receptor IIb decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of FCGR2B mRNA CTD PMID:12102619 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO S-Nitroso-N-Acetylpenicillamine promotes the reaction [FGF2 protein results in increased expression of TP53 protein] CTD PMID:16351512 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Ghrh growth hormone releasing hormone decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of GHRH mRNA CTD PMID:12102619 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Gnai2 G protein subunit alpha i2 multiple interactions
decreases expression
EXP 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]; Uric Acid inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein] CTD PMID:16962941 PMID:19252090 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions
decreases expression
EXP 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein]; Uric Acid inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein] CTD PMID:16962941 PMID:19252090 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of GOT1 mRNA CTD PMID:12102619 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]]; GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]]; GPX1 protein affects the susceptibility to [Diquat co-treated with S-Nitroso-N-Acetylpenicillamine]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased expression of GPX1 protein] CTD PMID:11672444 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions EXP [S-Nitroso-N-Acetylpenicillamine co-treated with 2-tert-butylhydroquinone] results in increased expression of GSTA2 CTD PMID:15357004 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of HCK mRNA CTD PMID:12102619 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP S-Nitroso-N-Acetylpenicillamine results in increased expression of HMOX1 protein CTD PMID:16439612 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma multiple interactions ISO S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Streptozocin results in increased expression of IFNG protein] CTD PMID:15892581 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of ITPKA mRNA CTD PMID:12102619 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases expression
multiple interactions
increases phosphorylation
decreases phosphorylation
EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of MAPK1 protein]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of MAPK1 protein]
CTD PMID:15640287 PMID:19252090 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression
decreases phosphorylation
increases phosphorylation
multiple interactions
EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of MAPK3 protein
S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of MAPK3 protein
S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of MAPK3 protein]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of MAPK3 protein]
CTD PMID:15640287 PMID:19252090 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mme membrane metallo-endopeptidase decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of MME mRNA CTD PMID:12102619 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 affects localization ISO S-Nitroso-N-Acetylpenicillamine affects the localization of MTF1 protein CTD PMID:16423564 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of NFKB1 mRNA CTD PMID:12102619 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nos2 nitric oxide synthase 2 decreases activity
decreases expression
ISO
EXP
S-Nitroso-N-Acetylpenicillamine results in decreased activity of NOS2 protein
S-Nitroso-N-Acetylpenicillamine results in decreased expression of NOS2 promoter
CTD PMID:11076874 PMID:15565661 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP [S-Nitroso-N-Acetylpenicillamine co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:11799084 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions
decreases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of NPR3 protein] CTD PMID:16962941 PMID:19252090 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCA protein]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RAF1 protein]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RGS17 protein] CTD PMID:18652891 PMID:21235400 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of PAM mRNA CTD PMID:12102619 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]] CTD PMID:10811113 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCA protein] CTD PMID:18652891 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein] CTD PMID:18652891 PMID:21235400 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 multiple interactions
increases activity
EXP [S-Nitroso-N-Acetylpenicillamine co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]
S-Nitroso-N-Acetylpenicillamine results in increased activity of PRKG1 protein
CTD PMID:11799084 NCBI chr 1:228,409,883...229,638,794 JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of RACK1 mRNA CTD PMID:12102619 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RAF1 protein] CTD PMID:21235400 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rgs17 regulator of G-protein signaling 17 multiple interactions ISO S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RGS17 protein] CTD PMID:18652891 NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 decreases expression EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of RPLP0 mRNA CTD PMID:12102619 NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632
JBrowse link
G Sftpa1 surfactant protein A1 decreases expression
multiple interactions
EXP S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPA1 mRNA
bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPA1 mRNA]; PD 156707 inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPA1 mRNA]
CTD PMID:15640287 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685
JBrowse link
G Sftpb surfactant protein B multiple interactions
decreases expression
EXP bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPB mRNA]; PD 156707 inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPB mRNA] CTD PMID:15640287 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Sftpc surfactant protein C multiple interactions
decreases expression
EXP bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPC mRNA]; PD 156707 inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPC mRNA] CTD PMID:15640287 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
affects response to substance
ISO GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]
SOD1 protein affects the susceptibility to S-Nitroso-N-Acetylpenicillamine
CTD PMID:10698074 PMID:11672444 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO
EXP
GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]
[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased expression of and results in increased activity of SOD2 protein; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA
CTD PMID:11672444 PMID:14996425 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased expression of TRP53 mRNA
S-Nitroso-N-Acetylpenicillamine promotes the reaction [FGF2 protein results in increased expression of TP53 protein]
CTD PMID:7673702 PMID:16351512 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 multiple interactions EXP S-Nitroso-N-Acetylpenicillamine inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein] CTD PMID:20177073 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases phosphorylation EXP S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of VASP protein CTD PMID:11799084 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
increases secretion
EXP S-Nitroso-N-Acetylpenicillamine results in increased expression of VEGFA mRNA
S-Nitroso-N-Acetylpenicillamine results in increased secretion of VEGFA protein
CTD PMID:10613739 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      chemical role 19320
        donor 18633
          nitric oxide donor 2772
            S-nitroso-N-acetyl-D-penicillamine 56
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        carboacyl group 17469
                                          univalent carboacyl group 17469
                                            carbamoyl group 17285
                                              carboxamide 17285
                                                N-acyl-amino acid 10069
                                                  N-acyl-D-amino acid 60
                                                    N-acetyl-D-amino acid 56
                                                      N-acetyl-D-penicillamine 56
                                                        S-nitroso-N-acetyl-D-penicillamine 56
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