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Accession:CHEBI:77572 term browser browse the term
Definition:An amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group.
Synonyms:exact_synonym: 2-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid
 related_synonym: Formula=C18H17NO5;   InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+;   InChIKey=NZHGWWWHIYHZNX-CSKARUKUSA-N;   MK-341;   N-(3,4-Dimethoxycinnamoyl)anthranilic acid;   Rizaben;   SMILES=COc1ccc(\\C=C\\C(=O)Nc2ccccc2C(O)=O)cc1OC;   tranilastum
 xref: CAS:53902-12-8 "ChemIDplus";   CAS:53902-12-8 "KEGG DRUG";   Drug_Central:2714 "DrugCentral";   KEGG:D02027
 xref_mesh: MESH:C012293
 xref: PDBeChem:D27;   PMID:22753703 "Europe PMC";   PMID:23121382 "Europe PMC";   PMID:23273396 "Europe PMC";   PMID:23363021 "Europe PMC";   PMID:23679559 "Europe PMC";   PMID:23694807 "Europe PMC";   PMID:23715805 "Europe PMC";   PMID:23821545 "Europe PMC";   PMID:23977380 "Europe PMC";   PMID:24055688 "Europe PMC";   PMID:24092987 "Europe PMC";   PMID:24143895 "Europe PMC";   PMID:24157455 "Europe PMC";   PMID:24374452 "Europe PMC";   PMID:24377619 "Europe PMC";   PMID:24384948 "Europe PMC";   PMID:24389486 "Europe PMC";   PMID:24389817 "Europe PMC";   PMID:24420060 "Europe PMC";   PMID:24448965 "Europe PMC";   PMID:24475260 "Europe PMC";   PMID:24476069 "Europe PMC";   Reaxys:3085768 "Reaxys";   Wikipedia:Tranilast

show annotations for term's descendants       view all columns           Sort by:
tranilast term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        anti-asthmatic agent 9177
          anti-asthmatic drug 8548
            tranilast 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                alpha,beta-unsaturated carboxylic acid amide 4750
                                                  enamide 4750
                                                    cinnamamides 1305
                                                      tranilast 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.