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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,1-bis(phosphonic acid)
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Accession:CHEBI:77383 term browser browse the term
Definition:Any member of the class of phosphonic acids in which a carbon atom is directly attached to two phosphonic acid groups. They are analogues of pyrophosphates (with the central oxygen atom replaced by a carbon atom) and like pyrophosphates they tend to have a strong affinity for bone, so are frequently used for their antiresorptive and hypocalcaemic properties.
Synonyms:related_synonym: 1,1-bis(phosphonic acid)s;   1,1-diphosphonate;   1,1-diphosphonates;   1,1-diphosphonic acid;   1,1-diphosphonic acids;   Formula=CH4O6P2R2;   SMILES=OP(O)(=O)C([*])([*])P(O)(O)=O;   bis(phosphonic acid);   bis(phosphonic acid)s;   bisphosphonate;   bisphosphonates;   diphosphonic acid
 xref: Wikipedia:Bisphosphonate


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alendronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO Alendronate inhibits the reaction [Streptozocin results in increased activity of ACHE protein] CTD PMID:30481507 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions EXP Alendronate inhibits the reaction [Dexamethasone results in increased activity of ACP5 protein]; Alendronate inhibits the reaction [modafinil results in increased expression of ACP5 mRNA] CTD PMID:27387537 PMID:29649498 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 affects expression EXP Alendronate affects the expression of ADCYAP1 mRNA CTD PMID:16079270 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions EXP Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]; Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]] CTD PMID:30291735 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Alendronate inhibits the reaction [Streptozocin results in increased expression of APP protein] CTD PMID:30481507 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects expression EXP Alendronate affects the expression of ATP1A1 mRNA CTD PMID:16079270 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] CTD PMID:30481507 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions EXP [Nebivolol co-treated with Alendronate] inhibits the reaction [Methylprednisolone results in decreased secretion of BGLAP protein] CTD PMID:30291735 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Casp9 caspase 9 multiple interactions ISO TNFSF11 inhibits the reaction [Alendronate results in increased expression of CASP9 protein] CTD PMID:19405951 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions EXP
ISO
Alendronate inhibits the reaction [Methylprednisolone results in decreased activity of CAT protein]; Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in decreased activity of CAT protein]]
Alendronate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
CTD PMID:30291735 PMID:30481507 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cd3g CD3g molecule affects expression EXP Alendronate affects the expression of CD3G mRNA CTD PMID:16079270 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Cdh2 cadherin 2 affects expression EXP Alendronate affects the expression of CDH2 mRNA CTD PMID:16079270 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdh6 cadherin 6 affects expression EXP Alendronate affects the expression of CDH6 mRNA CTD PMID:16079270 NCBI chr 2:63,100,723...63,246,618
Ensembl chr 2:63,101,739...63,166,509
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 affects expression EXP Alendronate affects the expression of CDK5RAP3 mRNA CTD PMID:16079270 NCBI chr10:84,780,644...84,789,800
Ensembl chr10:84,780,608...84,789,832
JBrowse link
G Col11a1 collagen type XI alpha 1 chain affects expression EXP Alendronate affects the expression of COL11A1 mRNA CTD PMID:16079270 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col5a1 collagen type V alpha 1 chain affects expression EXP Alendronate affects the expression of COL5A1 mRNA CTD PMID:16079270 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a2 collagen type V alpha 2 chain affects expression EXP Alendronate affects the expression of COL5A2 mRNA CTD PMID:16079270 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Cpe carboxypeptidase E affects expression EXP Alendronate affects the expression of CPE mRNA CTD PMID:16079270 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Crybb2 crystallin, beta B2 affects expression EXP Alendronate affects the expression of CRYBB2 mRNA CTD PMID:16079270 NCBI chr12:49,577,580...49,588,555
Ensembl chr12:49,578,633...49,588,555
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression EXP Alendronate affects the expression of CYP2A1 mRNA CTD PMID:16079270 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Dusp6 dual specificity phosphatase 6 affects expression EXP Alendronate affects the expression of DUSP6 mRNA CTD PMID:16079270 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 affects expression EXP Alendronate affects the expression of EGLN3 mRNA CTD PMID:16079270 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Fdps farnesyl diphosphate synthase decreases activity ISO Alendronate results in decreased activity of FDPS protein CTD PMID:11160603 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fgf9 fibroblast growth factor 9 affects expression EXP Alendronate affects the expression of FGF9 mRNA CTD PMID:16079270 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fkbp3 FKBP prolyl isomerase 3 affects expression EXP Alendronate affects the expression of FKBP3 mRNA CTD PMID:16079270 NCBI chr 6:86,810,865...86,822,115
Ensembl chr 6:86,810,809...86,822,094
JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 affects expression EXP Alendronate affects the expression of GABRG1 mRNA CTD PMID:16079270 NCBI chr14:39,964,502...40,051,306
Ensembl chr14:39,964,588...40,049,354
JBrowse link
G Ghrh growth hormone releasing hormone affects expression EXP Alendronate affects the expression of GHRH mRNA CTD PMID:16079270 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794
JBrowse link
G Ghrhr growth hormone releasing hormone receptor affects expression EXP Alendronate affects the expression of GHRHR mRNA CTD PMID:16079270 NCBI chr 4:85,587,321...85,602,389
Ensembl chr 4:85,588,595...85,601,666
JBrowse link
G Gnb1 G protein subunit beta 1 affects expression EXP Alendronate affects the expression of GNB1 mRNA CTD PMID:16079270 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Alendronate affects the expression of HAL mRNA CTD PMID:16079270 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hmgb1 high mobility group box 1 affects expression EXP Alendronate affects the expression of HMGB1 mRNA CTD PMID:16079270 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hoxa1 homeobox A1 affects expression EXP Alendronate affects the expression of HOXA1 mRNA CTD PMID:16079270 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases prenylation ISO Alendronate results in decreased prenylation of HRAS protein CTD PMID:9556058 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A affects expression EXP Alendronate affects the expression of HTR5A mRNA CTD PMID:16079270 NCBI chr 4:199,916...209,599
Ensembl chr 4:199,916...209,599
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 affects expression EXP Alendronate affects the expression of IDH2 mRNA CTD PMID:16079270 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein] CTD PMID:21430599 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO
EXP
Alendronate results in increased expression of IL1B protein
Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]
[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein; [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Alendronate promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Clodronic Acid inhibits the reaction [Alendronate results in increased expression of IL1B protein]; Farnesol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geranylgeraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; Menthol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]
CTD PMID:17375077 PMID:20304105 PMID:20804833 PMID:21430599 PMID:30481507 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions EXP Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA] CTD PMID:17375077 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Alendronate inhibits the reaction [Streptozocin results in increased expression of IL6 protein] CTD PMID:30481507 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kcnh5 potassium voltage-gated channel subfamily H member 5 affects expression EXP Alendronate affects the expression of KCNH5 mRNA CTD PMID:16079270 NCBI chr 6:97,872,831...98,157,087
Ensembl chr 6:97,872,831...98,157,087
JBrowse link
G Lox lysyl oxidase affects expression EXP Alendronate affects the expression of LOX mRNA CTD PMID:16079270 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Alendronate affects the expression of MAPK14 mRNA CTD PMID:16079270 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
affects expression
decreases secretion
ISO
EXP
Alendronate results in decreased expression of MMP2 mRNA
Alendronate affects the expression of MMP2 mRNA
Alendronate results in decreased secretion of MMP2 protein
CTD PMID:15049011 PMID:16079270 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Muc1 mucin 1, cell surface associated affects expression EXP Alendronate affects the expression of MUC1 mRNA CTD PMID:16079270 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Myl9 myosin light chain 9 affects expression EXP Alendronate affects the expression of MYL9 mRNA CTD PMID:16079270 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 affects expression EXP Alendronate affects the expression of NECTIN1 mRNA CTD PMID:16079270 NCBI chr 8:48,094,233...48,198,499
Ensembl chr 8:48,094,673...48,157,305
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein] CTD PMID:17375077 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Olr1696 olfactory receptor 1696 affects expression EXP Alendronate affects the expression of OLR1696 mRNA CTD PMID:16079270 NCBI chr20:878,460...879,425 JBrowse link
G Pcolce procollagen C-endopeptidase enhancer affects expression EXP Alendronate affects the expression of PCOLCE mRNA CTD PMID:16079270 NCBI chr12:22,153,995...22,160,311
Ensembl chr12:22,153,983...22,160,337
JBrowse link
G Pex5 peroxisomal biogenesis factor 5 affects expression EXP Alendronate affects the expression of PEX5 mRNA CTD PMID:16079270 NCBI chr 4:156,983,914...157,009,675
Ensembl chr 4:156,983,915...157,009,674
Ensembl chr 4:156,983,915...157,009,674
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 affects expression EXP Alendronate affects the expression of PHLPP mRNA CTD PMID:16079270 NCBI chr13:26,145,989...26,394,505
Ensembl chr13:26,172,243...26,394,505
JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 affects expression EXP Alendronate affects the expression of PIAS3 mRNA CTD PMID:16079270 NCBI chr 2:198,821,377...198,831,533
Ensembl chr 2:198,823,366...198,836,372
JBrowse link
G Pigr polymeric immunoglobulin receptor affects expression EXP Alendronate affects the expression of PIGR mRNA CTD PMID:16079270 NCBI chr13:47,564,176...47,592,093
Ensembl chr13:47,572,219...47,591,699
JBrowse link
G Plpp1 phospholipid phosphatase 1 affects expression EXP Alendronate affects the expression of PLPP1 mRNA CTD PMID:16079270 NCBI chr 2:44,664,076...44,726,820
Ensembl chr 2:44,664,124...44,726,689
JBrowse link
G Pon1 paraoxonase 1 decreases activity
multiple interactions
EXP Alendronate results in decreased activity of PON1 protein
[Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of homocysteine thiolactone; [Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of Paraoxon; [Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of phenyl acetate
CTD PMID:27387541 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Psap prosaposin affects expression EXP Alendronate affects the expression of PSAP mRNA CTD PMID:16079270 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
G Psme1 proteasome activator subunit 1 affects expression EXP Alendronate affects the expression of PSME1 mRNA CTD PMID:16079270 NCBI chr15:34,256,071...34,258,947
Ensembl chr15:34,256,071...34,258,947
JBrowse link
G Ptgfrn prostaglandin F2 receptor inhibitor affects expression EXP Alendronate affects the expression of PTGFRN mRNA CTD PMID:16079270 NCBI chr 2:203,423,143...203,494,391
Ensembl chr 2:203,423,143...203,494,391
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein] CTD PMID:17375077 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases prenylation ISO Alendronate results in decreased prenylation of RAP1A protein CTD PMID:11595616 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rara retinoic acid receptor, alpha affects expression EXP Alendronate affects the expression of RARA mRNA CTD PMID:16079270 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions EXP Alendronate promotes the reaction [modafinil results in increased expression of RUNX2 mRNA] CTD PMID:29649498 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Scn4a sodium voltage-gated channel alpha subunit 4 affects expression EXP Alendronate affects the expression of SCN4A mRNA CTD PMID:16079270 NCBI chr10:94,505,026...94,557,803
Ensembl chr10:94,505,026...94,557,764
JBrowse link
G Serpine2 serpin family E member 2 affects expression EXP Alendronate affects the expression of SERPINE2 mRNA CTD PMID:16079270 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Serpinh1 serpin family H member 1 affects expression EXP Alendronate affects the expression of SERPINH1 mRNA CTD PMID:16079270 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317
JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects expression EXP Alendronate affects the expression of SLC18A2 mRNA CTD PMID:16079270 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc19a1 solute carrier family 19 member 1 affects expression EXP Alendronate affects the expression of SLC19A1 mRNA CTD PMID:16079270 NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377
JBrowse link
G Slc6a4 solute carrier family 6 member 4 affects expression EXP Alendronate affects the expression of SLC6A4 mRNA CTD PMID:16079270 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Slit1 slit guidance ligand 1 affects expression EXP Alendronate affects the expression of SLIT1 mRNA CTD PMID:16079270 NCBI chr 1:260,843,481...260,992,366
Ensembl chr 1:260,843,483...260,992,366
JBrowse link
G Snn stannin affects expression EXP Alendronate affects the expression of SNN mRNA CTD PMID:16079270 NCBI chr10:4,635,897...4,644,570
Ensembl chr10:4,635,898...4,644,570
JBrowse link
G Sparc secreted protein acidic and cysteine rich affects expression EXP Alendronate affects the expression of SPARC mRNA CTD PMID:16079270 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Stk4 serine/threonine kinase 4 increases cleavage ISO Alendronate results in increased cleavage of STK4 protein CTD PMID:14502240 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Alendronate co-treated with zoledronic acid] results in increased expression of TGFB1 protein CTD PMID:18504149 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression EXP Alendronate affects the expression of TIMP1 mRNA CTD PMID:16079270 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein; Alendronate inhibits the reaction [Streptozocin results in increased expression of TNF protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein] CTD PMID:21430599 PMID:30481507 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions EXP Alendronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; Alendronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein] CTD PMID:27387537 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO
EXP
TNFSF11 inhibits the reaction [Alendronate results in increased expression of CASP9 protein]
Alendronate inhibits the reaction [Dexamethasone results in increased expression of TNFSF11 mRNA]; Alendronate inhibits the reaction [Dexamethasone results in increased expression of TNFSF11 protein]; Alendronate inhibits the reaction [modafinil results in increased expression of TNFSF11 mRNA]
CTD PMID:19405951 PMID:27387537 PMID:29649498 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tnni3 troponin I3, cardiac type affects expression EXP Alendronate affects the expression of TNNI3 mRNA CTD PMID:16079270 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Vdr vitamin D receptor affects response to substance
multiple interactions
ISO VDR gene polymorphism affects the susceptibility to Alendronate
VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]; VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Raloxifene Hydrochloride]
CTD PMID:12608943 PMID:15739035 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
clodronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Clodronic Acid results in decreased expression of AARS1 mRNA CTD PMID:25596134 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression ISO Clodronic Acid results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:37,923,974...37,956,678
Ensembl chr12:37,923,528...37,958,363
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO Clodronic Acid results in increased expression of ABCC3 mRNA CTD PMID:25596134 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Clodronic Acid results in decreased expression of ABCG1 mRNA CTD PMID:25596134 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Clodronic Acid results in increased expression of ABHD4 mRNA CTD PMID:25596134 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Clodronic Acid results in decreased expression of ACSL1 mRNA CTD PMID:25596134 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP [Clodronic Acid co-treated with Thioacetamide] results in increased expression of ACTA2 protein CTD PMID:26957569 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Agrn agrin increases expression ISO Clodronic Acid results in increased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Ahr aryl hydrocarbon receptor affects activity ISO Clodronic Acid affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 affects expression ISO Clodronic Acid affects the expression of AIFM2 mRNA CTD PMID:25596134 NCBI chr20:31,329,047...31,353,548
Ensembl chr20:31,339,787...31,352,906
JBrowse link
G Ak3 adenylate kinase 3 increases expression ISO Clodronic Acid results in increased expression of AK3 mRNA CTD PMID:25596134 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Clodronic Acid results in increased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Clodronic Acid results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Clodronic Acid results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Als2cl ALS2 C-terminal like affects expression ISO Clodronic Acid affects the expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:119,156,081...119,176,680
Ensembl chr 8:119,160,731...119,174,830
JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression ISO Clodronic Acid results in decreased expression of ANGPTL4 mRNA CTD PMID:25596134 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankra2 ankyrin repeat family A member 2 decreases expression ISO Clodronic Acid results in decreased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr  X:82,407,601...82,418,229
Ensembl chr  X:82,407,598...82,418,425
Ensembl chr 2:82,407,598...82,418,425
JBrowse link
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 affects expression ISO Clodronic Acid affects the expression of ARFGEF2 mRNA CTD PMID:25596134 NCBI chr 3:163,570,435...163,656,612
Ensembl chr 3:163,570,532...163,656,626
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 decreases expression ISO Clodronic Acid results in decreased expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr16:79,725,629...79,817,065
Ensembl chr16:79,725,643...79,793,619
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 increases expression ISO Clodronic Acid results in increased expression of ARL1 mRNA CTD PMID:25596134 NCBI chr 7:29,282,411...29,293,455
Ensembl chr 7:29,282,305...29,293,399
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Clodronic Acid results in decreased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Astn2 astrotactin 2 increases expression ISO Clodronic Acid results in increased expression of ASTN2 mRNA CTD PMID:25596134 NCBI chr 5:81,179,614...82,168,528
Ensembl chr 5:81,179,605...82,168,427
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Clodronic Acid results in increased expression of ATAD2 mRNA CTD PMID:25596134 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Atf3 activating transcription factor 3 decreases expression ISO Clodronic Acid results in decreased expression of ATF3 mRNA CTD PMID:25596134 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 affects activity ISO Clodronic Acid affects the activity of ATF4 protein CTD PMID:25596134 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Clodronic Acid results in decreased expression of ATXN1 mRNA CTD PMID:25596134 NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814
JBrowse link
G Aurkb aurora kinase B increases expression ISO Clodronic Acid results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Clodronic Acid results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor decreases expression ISO Clodronic Acid results in decreased expression of BATF mRNA CTD PMID:25596134 NCBI chr 6:109,562,415...109,584,541
Ensembl chr 6:109,562,587...109,584,545
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Clodronic Acid results in increased expression of BAX mRNA CTD PMID:25596134 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression ISO Clodronic Acid results in increased expression of BCAT1 mRNA CTD PMID:25596134 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 increases expression ISO Clodronic Acid results in increased expression of BCAT2 mRNA CTD PMID:25596134 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Bcl3 BCL3, transcription coactivator decreases expression ISO Clodronic Acid results in decreased expression of BCL3 mRNA CTD PMID:25596134 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Bend5 BEN domain containing 5 increases expression ISO Clodronic Acid results in increased expression of BEND5 mRNA CTD PMID:25596134 NCBI chr 5:131,257,127...131,312,335
Ensembl chr 5:131,257,127...131,312,335
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Clodronic Acid results in decreased expression of BNIP3 mRNA CTD PMID:25596134 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Brd2 bromodomain containing 2 decreases expression ISO Clodronic Acid results in decreased expression of BRD2 mRNA CTD PMID:25596134 NCBI chr20:3,910,555...3,921,074
Ensembl chr20:3,910,555...3,917,426
Ensembl chr20:3,910,555...3,917,426
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Clodronic Acid results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO Clodronic Acid results in increased expression of CAMKK2 mRNA CTD PMID:25596134 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Cars cysteinyl-tRNA synthetase decreases expression ISO Clodronic Acid results in decreased expression of CARS1 mRNA CTD PMID:25596134 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
ISO Clodronic Acid results in increased expression of CASP3
Suramin inhibits the reaction [Clodronic Acid results in increased expression of CASP3]
CTD PMID:19448140 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccdc90b coiled-coil domain containing 90B decreases expression ISO Clodronic Acid results in decreased expression of CCDC90B mRNA CTD PMID:25596134 NCBI chr 1:157,403,595...157,417,153
Ensembl chr 1:157,403,595...157,417,147
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Clodronic Acid results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng2 cyclin G2 decreases expression ISO Clodronic Acid results in decreased expression of CCNG2 mRNA CTD PMID:25596134 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of CD68 mRNA] CTD PMID:27022031 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD80 protein] CTD PMID:15892581 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD86 protein] CTD PMID:15892581 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdk6 cyclin-dependent kinase 6 affects expression ISO Clodronic Acid affects the expression of CDK6 mRNA CTD PMID:25596134 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Clodronic Acid results in increased expression of CDKN1A mRNA CTD PMID:25596134 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cers5 ceramide synthase 5 increases expression ISO Clodronic Acid results in increased expression of CERS5 mRNA CTD PMID:25596134 NCBI chr 7:141,386,391...141,424,375
Ensembl chr 7:141,386,391...141,424,343
JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 increases expression ISO Clodronic Acid results in increased expression of CLIP4 mRNA CTD PMID:25596134 NCBI chr 6:23,222,020...23,316,962
Ensembl chr 6:23,222,021...23,316,962
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO Clodronic Acid results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of COL1A1 mRNA] CTD PMID:27022031 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO Clodronic Acid results in increased expression of CRISPLD2 mRNA CTD PMID:25596134 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 decreases expression ISO Clodronic Acid results in decreased expression of CTDP1 mRNA CTD PMID:25596134 NCBI chr18:76,922,913...76,985,095
Ensembl chr18:76,922,934...76,984,203
JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO Clodronic Acid results in decreased expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctsc cathepsin C increases expression ISO Clodronic Acid results in increased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cttn cortactin increases expression ISO Clodronic Acid results in increased expression of CTTN mRNA CTD PMID:25596134 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Clodronic Acid results in increased expression of CYP1A2 mRNA CTD PMID:25596134 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Clodronic Acid results in increased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Ddb2 damage specific DNA binding protein 2 decreases expression ISO Clodronic Acid results in decreased expression of DDB2 mRNA CTD PMID:25596134 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression ISO Clodronic Acid affects the expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Clodronic Acid results in increased expression of DDIT4 mRNA CTD PMID:25596134 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression ISO Clodronic Acid results in decreased expression of DDX17 mRNA CTD PMID:25596134 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
JBrowse link
G Des desmin multiple interactions EXP [Clodronic Acid co-treated with Thioacetamide] results in increased expression of DES protein CTD PMID:26957569 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO Clodronic Acid results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:3,143,826...3,170,764
Ensembl chr 7:3,143,827...3,170,146
JBrowse link
G Dhx37 DEAH-box helicase 37 decreases expression ISO Clodronic Acid results in decreased expression of DHX37 mRNA CTD PMID:25596134 NCBI chr12:36,594,058...36,614,165
Ensembl chr12:36,594,047...36,614,210
JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO Clodronic Acid results in increased expression of DLGAP5 mRNA CTD PMID:25596134 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 decreases expression ISO Clodronic Acid results in decreased expression of DNAI3 mRNA CTD PMID:25596134 NCBI chr 2:251,912,432...251,970,699
Ensembl chr 2:251,912,368...251,970,768
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Clodronic Acid results in increased expression of DNAJB9 mRNA CTD PMID:25596134 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory increases expression ISO Clodronic Acid results in increased expression of DPM3 mRNA CTD PMID:25596134 NCBI chr 2:188,583,664...188,584,179
Ensembl chr 2:188,583,664...188,584,179
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 increases expression ISO Clodronic Acid results in increased expression of DPYSL3 mRNA CTD PMID:25596134 NCBI chr18:37,716,371...37,819,347
Ensembl chr18:37,716,143...37,819,097
JBrowse link
G Dusp22 dual specificity phosphatase 22 increases expression ISO Clodronic Acid results in increased expression of DUSP22 mRNA CTD PMID:25596134 NCBI chr17:34,986,589...35,037,297
Ensembl chr17:34,986,591...35,037,076
JBrowse link
G Efna1 ephrin A1 decreases expression ISO Clodronic Acid results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Clodronic Acid results in increased expression of EIF1 mRNA CTD PMID:25596134 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta increases expression ISO Clodronic Acid results in increased expression of EIF2S2 mRNA CTD PMID:25596134 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression ISO Clodronic Acid results in decreased expression of EIF3C mRNA CTD PMID:25596134 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Elf4 E74 like ETS transcription factor 4 decreases expression ISO Clodronic Acid results in decreased expression of ELF4 mRNA CTD PMID:25596134 NCBI chr  X:135,239,626...135,284,330
Ensembl chr  X:135,240,451...135,250,519
JBrowse link
G Elk4 ETS transcription factor ELK4 decreases expression ISO Clodronic Acid results in decreased expression of ELK4 mRNA CTD PMID:25596134 NCBI chr13:48,788,262...48,813,267
Ensembl chr13:48,790,509...48,813,260
JBrowse link
G Eno2 enolase 2 increases expression ISO Clodronic Acid results in increased expression of ENO2 mRNA CTD PMID:25596134 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
Ensembl chr 9:157,285,179...157,294,047
JBrowse link
G Ep400 E1A binding protein p400 decreases expression ISO Clodronic Acid results in decreased expression of EP400 mRNA CTD PMID:25596134 NCBI chr12:51,948,650...52,055,274
Ensembl chr12:51,948,650...52,055,271
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase decreases expression ISO Clodronic Acid results in decreased expression of EPRS1 mRNA CTD PMID:25596134 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression ISO Clodronic Acid results in decreased expression of FAM162A mRNA CTD PMID:25596134 NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253
JBrowse link
G Fam210a family with sequence similarity 210, member A affects expression ISO Clodronic Acid affects the expression of FAM210A mRNA CTD PMID:25596134 NCBI chr18:64,045,023...64,084,594
Ensembl chr18:64,045,432...64,084,556
JBrowse link
G Fam214a family with sequence similarity 214, member A decreases expression ISO Clodronic Acid results in decreased expression of FAM214A mRNA CTD PMID:25596134 NCBI chr 8:81,863,619...81,941,548
Ensembl chr 8:81,863,619...81,941,536
JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Clodronic Acid results in increased expression of FAM89A mRNA CTD PMID:25596134 NCBI chr19:57,502,308...57,514,896
Ensembl chr19:57,502,308...57,514,896
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Clodronic Acid results in decreased expression of FAS mRNA CTD PMID:25596134 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO Clodronic Acid results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fbxo30 F-box protein 30 decreases expression ISO Clodronic Acid results in decreased expression of FBXO30 mRNA CTD PMID:25596134 NCBI chr 1:5,366,119...5,389,774
Ensembl chr 1:5,366,379...5,388,069
JBrowse link
G Fech ferrochelatase decreases expression ISO Clodronic Acid results in decreased expression of FECH mRNA CTD PMID:25596134 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Flvcr2 FLVCR heme transporter 2 increases expression ISO Clodronic Acid results in increased expression of FLVCR2 mRNA CTD PMID:25596134 NCBI chr 6:109,617,348...109,681,495
Ensembl chr 6:109,617,355...109,681,495
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Clodronic Acid results in increased expression of FOSL1 mRNA CTD PMID:25596134 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit decreases expression ISO Clodronic Acid results in decreased expression of FOSL2 mRNA CTD PMID:25596134 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 decreases expression ISO Clodronic Acid results in decreased expression of FREM2 mRNA CTD PMID:25596134 NCBI chr 2:142,747,501...142,885,604
Ensembl chr 2:142,747,501...142,885,604
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression ISO Clodronic Acid results in decreased expression of FTH1 mRNA CTD PMID:25596134 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Clodronic Acid results in increased expression of GABARAPL1 mRNA CTD PMID:25596134 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
JBrowse link
G Gars glycyl-tRNA synthetase increases expression ISO Clodronic Acid results in increased expression of GARS1 mRNA CTD PMID:25596134 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Clodronic Acid results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Clodronic Acid results in increased expression of GCLM mRNA CTD PMID:25596134 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdf15 growth differentiation factor 15 decreases expression ISO Clodronic Acid results in decreased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Golim4 golgi integral membrane protein 4 increases expression ISO Clodronic Acid results in increased expression of GOLIM4 mRNA CTD PMID:25596134 NCBI chr 2:174,321,303...174,413,847
Ensembl chr 2:174,322,673...174,413,236
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Clodronic Acid results in increased expression of GPAT3 mRNA CTD PMID:25596134 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Clodronic Acid results in increased expression of GPNMB mRNA CTD PMID:25596134 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr87 G protein-coupled receptor 87 decreases expression ISO Clodronic Acid results in decreased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:149,398,949...149,418,041
Ensembl chr 2:149,398,949...149,417,212
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO
EXP
Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased secretion of GPT protein]
Clodronic Acid promotes the reaction [Thioacetamide results in increased expression of GPT protein]
CTD PMID:26957569 PMID:27022031 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Clodronic Acid results in increased expression of GSR mRNA CTD PMID:25596134 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
affects activity
EXP
ISO
Clodronic Acid inhibits the reaction [Dopamine results in decreased expression of HIF1A protein]
Clodronic Acid affects the activity of HIF1A protein
CTD PMID:25596134 PMID:25818600 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
increases expression
ISO Clodronic Acid results in decreased expression of HMOX1 mRNA
Clodronic Acid results in increased expression of HMOX1 mRNA
CTD PMID:21690482 PMID:25596134 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 affects expression ISO Clodronic Acid affects the expression of IARS1 mRNA CTD PMID:25596134 NCBI chr17:15,356,016...15,402,680
Ensembl chr17:15,355,529...15,402,649
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein] CTD PMID:15892581 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Clodronic Acid results in decreased expression of IDS mRNA CTD PMID:25596134 NCBI chr 8:69,447,971...69,466,708
Ensembl chr 8:69,449,801...69,466,618
JBrowse link
G Ifng interferon gamma multiple interactions ISO Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of IFNG protein] CTD PMID:15892581 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO Clodronic Acid results in increased expression of IGF1R mRNA CTD PMID:25596134 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Clodronic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 protein] CTD PMID:32385136 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO Clodronic Acid inhibits the reaction [Alendronate results in increased expression of IL1B protein]
Clodronic Acid results in increased expression of IL1B mRNA
CTD PMID:20804833 PMID:25187657 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
Clodronic Acid inhibits the reaction [Taurocholic Acid results in increased expression of IL6 protein]
Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of IL6 mRNA]
CTD PMID:20382593 PMID:27022031 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO Clodronic Acid results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Clodronic Acid results in increased expression of KEAP1 mRNA CTD PMID:25596134 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO Clodronic Acid results in increased expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838
JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO Clodronic Acid results in decreased expression of LTN1 mRNA CTD PMID:25596134 NCBI chr11:27,023,328...27,080,575
Ensembl chr11:27,022,986...27,080,701
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Clodronic Acid results in increased expression of MAFG mRNA CTD PMID:25596134 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 increases expression ISO Clodronic Acid results in increased expression of MAPRE2 mRNA CTD PMID:25596134 NCBI chr18:14,814,149...15,780,290 JBrowse link
G Mcoln2 mucolipin TRP cation channel 2 decreases expression ISO Clodronic Acid results in decreased expression of MCOLN2 mRNA CTD PMID:25596134 NCBI chr 2:252,018,594...252,068,209
Ensembl chr 2:252,018,597...252,068,271
JBrowse link
G Me1 malic enzyme 1 decreases expression ISO Clodronic Acid results in decreased expression of ME1 mRNA CTD PMID:25596134 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mtdh metadherin decreases expression ISO Clodronic Acid results in decreased expression of MTDH mRNA CTD PMID:25596134 NCBI chr 7:72,771,018...72,830,599
Ensembl chr 7:72,772,440...72,827,908
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming decreases expression ISO Clodronic Acid results in decreased expression of MUC2 mRNA CTD PMID:25187657 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Clodronic Acid results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:274,030,748...274,090,071
Ensembl chr 1:274,030,978...274,090,071
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO Clodronic Acid results in decreased expression of NARS1 mRNA CTD PMID:25596134 NCBI chr18:59,986,350...60,002,644
Ensembl chr18:59,986,360...60,002,569
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression ISO Clodronic Acid results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects activity ISO Clodronic Acid affects the activity of NFE2L2 protein CTD PMID:25596134 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nin ninein decreases expression ISO Clodronic Acid results in decreased expression of NIN mRNA CTD PMID:25596134 NCBI chr 6:92,423,412...92,527,776
Ensembl chr 6:92,433,381...92,527,711
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Clodronic Acid results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Clodronic Acid results in decreased expression of NR3C1 mRNA CTD PMID:25596134 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrep neuronal regeneration related protein increases expression ISO Clodronic Acid results in increased expression of NREP mRNA CTD PMID:25596134 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO Clodronic Acid results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:58,565,576...58,579,276
Ensembl chr19:58,565,576...58,579,265
JBrowse link
G Nuak1 NUAK family kinase 1 decreases expression ISO Clodronic Acid results in decreased expression of NUAK1 mRNA CTD PMID:25596134 NCBI chr 7:25,039,336...25,111,118
Ensembl chr 7:25,039,335...25,113,664
JBrowse link
G Orai3 ORAI calcium release-activated calcium modulator 3 decreases expression ISO Clodronic Acid results in decreased expression of ORAI3 mRNA CTD PMID:25596134 NCBI chr 1:199,217,504...199,222,363
Ensembl chr 1:199,217,016...199,222,851
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression ISO Clodronic Acid results in decreased expression of OSGIN1 mRNA CTD PMID:25596134 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO Clodronic Acid results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Pde8a phosphodiesterase 8A decreases expression ISO Clodronic Acid results in decreased expression of PDE8A mRNA CTD PMID:25596134 NCBI chr 1:143,036,083...143,160,395
Ensembl chr 1:143,036,218...143,159,433
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO Clodronic Acid results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:68,493,035...68,578,999
Ensembl chr11:68,493,035...68,578,995
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO Clodronic Acid results in decreased expression of PDK1 mRNA CTD PMID:25596134 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO Clodronic Acid results in increased expression of PDK4 mRNA CTD PMID:25596134 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression ISO Clodronic Acid results in increased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr 1:259,308,326...259,357,006
Ensembl chr 1:259,308,296...259,357,056
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 decreases expression ISO Clodronic Acid results in decreased expression of PFKFB4 mRNA CTD PMID:25596134 NCBI chr 8:117,733,347...117,776,525
Ensembl chr 8:117,737,117...117,775,386
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Clodronic Acid results in decreased expression of PHGDH mRNA CTD PMID:25596134 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma affects expression ISO Clodronic Acid affects the expression of PIP5K1C mRNA CTD PMID:25596134 NCBI chr 7:11,267,207...11,294,291
Ensembl chr 7:11,267,218...11,294,249
JBrowse link
G Pir pirin increases expression ISO Clodronic Acid results in increased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Plec plectin decreases expression ISO Clodronic Acid results in decreased expression of PLEC mRNA CTD PMID:25596134 NCBI chr 7:117,230,319...117,291,859
Ensembl chr 7:117,230,319...117,289,961
JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Clodronic Acid results in increased expression of PLK3 mRNA CTD PMID:25596134 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 decreases expression ISO Clodronic Acid results in decreased expression of PMAIP1 mRNA CTD PMID:25596134 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 affects expression ISO Clodronic Acid affects the expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases expression ISO Clodronic Acid results in decreased expression of PNPLA6 mRNA CTD PMID:25596134 NCBI chr12:2,068,749...2,098,139
Ensembl chr12:2,069,959...2,097,904
JBrowse link
G Polr3f RNA polymerase III subunit F decreases expression ISO Clodronic Acid results in decreased expression of POLR3F mRNA CTD PMID:25596134 NCBI chr 3:138,684,685...138,701,055
Ensembl chr 3:138,684,685...138,701,055
JBrowse link
G Pon1 paraoxonase 1 decreases activity
multiple interactions
EXP Clodronic Acid results in decreased activity of PON1 protein
[Clodronic Acid results in decreased activity of PON1 protein] which results in decreased metabolism of homocysteine thiolactone; [Clodronic Acid results in decreased activity of PON1 protein] which results in decreased metabolism of Paraoxon; [Clodronic Acid results in decreased activity of PON1 protein] which results in decreased metabolism of phenyl acetate
CTD PMID:27387541 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO Clodronic Acid affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppfibp1 PPFIA binding protein 1 affects expression ISO Clodronic Acid affects the expression of PPFIBP1 mRNA CTD PMID:25596134 NCBI chr 4:181,285,179...181,428,157
Ensembl chr 4:181,286,455...181,428,157
JBrowse link
G Ppig peptidylprolyl isomerase G decreases expression ISO Clodronic Acid results in decreased expression of PPIG mRNA CTD PMID:25596134 NCBI chr 3:55,959,756...55,990,040
Ensembl chr 3:55,960,067...55,988,968
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D decreases expression ISO Clodronic Acid results in decreased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO Clodronic Acid results in decreased expression of PPP1R15A mRNA CTD PMID:25596134 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 decreases expression ISO Clodronic Acid results in decreased expression of PPP4R2 mRNA CTD PMID:25596134 NCBI chr 4:133,285,552...133,323,755
Ensembl chr 4:133,285,552...133,323,755
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO Clodronic Acid results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prdm1 PR/SET domain 1 decreases expression ISO Clodronic Acid results in decreased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 increases expression ISO Clodronic Acid results in increased expression of PRKAB1 mRNA CTD PMID:25596134 NCBI chr12:46,316,298...46,326,789
Ensembl chr12:46,316,236...46,326,790
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 decreases expression ISO Clodronic Acid results in decreased expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:199,831,990...199,847,623
Ensembl chr 2:199,831,990...199,847,629
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO Clodronic Acid results in increased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Pspc1 paraspeckle component 1 decreases expression ISO Clodronic Acid results in decreased expression of PSPC1 mRNA CTD PMID:25596134 NCBI chr15:36,946,914...37,030,273
Ensembl chr15:36,950,257...37,030,281
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of CD68 mRNA]; Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of COL1A1 mRNA]; Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of IL6 mRNA]; Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TGFB1 mRNA]; Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TIMP1 mRNA]; Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TNF mRNA]; Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased secretion of GPT protein] CTD PMID:27022031 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Clodronic Acid results in increased expression of PYCR1 mRNA CTD PMID:25596134 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Rab26 RAB26, member RAS oncogene family increases expression ISO Clodronic Acid results in increased expression of RAB26 mRNA CTD PMID:25596134 NCBI chr10:13,894,271...13,898,578
Ensembl chr10:13,893,290...13,898,855
JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression ISO Clodronic Acid results in increased expression of RAB31 mRNA CTD PMID:25596134 NCBI chr 9:113,370,072...113,504,606
Ensembl chr 9:113,370,033...113,504,605
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO Clodronic Acid results in decreased expression of RARA mRNA CTD PMID:25596134 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase increases expression ISO Clodronic Acid results in increased expression of RFFL mRNA CTD PMID:25596134 NCBI chr10:70,157,621...70,220,618
Ensembl chr10:70,157,621...70,220,582
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO Clodronic Acid results in increased expression of RIT1 mRNA CTD PMID:25596134 NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
JBrowse link
G Rnd3 Rho family GTPase 3 affects expression ISO Clodronic Acid affects the expression of RND3 mRNA CTD PMID:25596134 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758
JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Clodronic Acid results in decreased expression of RO60 mRNA CTD PMID:25596134 NCBI chr13:60,546,892...60,567,882
Ensembl chr13:60,546,912...60,567,882
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B decreases expression ISO Clodronic Acid results in decreased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Rrp12 ribosomal RNA processing 12 homolog decreases expression ISO Clodronic Acid results in decreased expression of RRP12 mRNA CTD PMID:25596134 NCBI chr 1:261,106,768...261,140,416
Ensembl chr 1:261,106,760...261,140,389
JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 affects expression ISO Clodronic Acid affects the expression of RSRC2 mRNA CTD PMID:25596134 NCBI chr12:38,274,290...38,294,294
Ensembl chr12:38,274,297...38,294,292
JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression ISO Clodronic Acid results in increased expression of RUNX1 mRNA CTD PMID:25596134 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO Clodronic Acid results in increased expression of RUNX2 mRNA CTD PMID:25596134 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Scamp1 secretory carrier membrane protein 1 increases expression ISO Clodronic Acid results in increased expression of SCAMP1 mRNA CTD PMID:25596134 NCBI chr 2:23,858,021...23,941,128
Ensembl chr 2:23,857,995...23,941,084
JBrowse link
G Sectm1b secreted and transmembrane 1B increases expression ISO Clodronic Acid results in increased expression of SECTM1 mRNA CTD PMID:25596134 NCBI chr10:110,251,363...110,260,577
Ensembl chr10:110,251,363...110,259,985
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO Clodronic Acid results in increased expression of SERTAD1 mRNA CTD PMID:25596134 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Setx senataxin decreases expression ISO Clodronic Acid results in decreased expression of SETX mRNA CTD PMID:25596134 NCBI chr 3:7,680,430...7,731,815
Ensembl chr 3:7,686,503...7,730,539
JBrowse link
G Sfn stratifin increases expression ISO Clodronic Acid results in increased expression of SFN mRNA CTD PMID:25596134 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 decreases expression ISO Clodronic Acid results in decreased expression of SHANK3 mRNA CTD PMID:25596134 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 increases expression ISO Clodronic Acid results in increased expression of SIAH2 mRNA CTD PMID:25596134 NCBI chr 2:148,874,151...148,891,900
Ensembl chr 2:148,874,151...148,891,900
JBrowse link
G Sipa1l2 signal-induced proliferation-associated 1 like 2 decreases expression ISO Clodronic Acid results in decreased expression of SIPA1L2 mRNA CTD PMID:25596134 NCBI chr19:58,236,201...58,399,842
Ensembl chr19:58,236,214...58,399,816
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor increases expression ISO Clodronic Acid results in increased expression of SIVA1 mRNA CTD PMID:25596134 NCBI chr 6:137,209,999...137,214,379
Ensembl chr 6:137,210,052...137,214,388
JBrowse link
G Slc12a8 solute carrier family 12, member 8 decreases expression ISO Clodronic Acid results in decreased expression of SLC12A8 mRNA CTD PMID:25596134 NCBI chr11:70,344,771...70,499,202
Ensembl chr11:70,344,797...70,499,200
JBrowse link
G Slc1a4 solute carrier family 1 member 4 decreases expression ISO Clodronic Acid results in decreased expression of SLC1A4 mRNA CTD PMID:25596134 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO Clodronic Acid results in decreased expression of SLC1A5 mRNA CTD PMID:25596134 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression ISO Clodronic Acid results in increased expression of SLC25A20 mRNA CTD PMID:25596134 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc3a2 solute carrier family 3 member 2 affects expression ISO Clodronic Acid affects the expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO Clodronic Acid results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
G Slc7a5 solute carrier family 7 member 5 affects expression ISO Clodronic Acid affects the expression of SLC7A5 mRNA CTD PMID:25596134 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Smap1 small ArfGAP 1 increases expression ISO Clodronic Acid results in increased expression of SMAP1 mRNA CTD PMID:25596134 NCBI chr 9:30,068,888...30,161,753
Ensembl chr 9:30,068,659...30,161,578
JBrowse link
G Son SON DNA and RNA binding protein decreases expression ISO Clodronic Acid results in decreased expression of SON mRNA CTD PMID:25596134 NCBI chr11:31,806,598...31,837,769
Ensembl chr11:31,806,618...31,837,763
JBrowse link
G Sorl1 sortilin related receptor 1 increases expression ISO Clodronic Acid results in increased expression of SORL1 mRNA CTD PMID:25596134 NCBI chr 8:46,228,077...46,287,171 JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 increases expression ISO Clodronic Acid results in increased expression of SPRY1 mRNA CTD PMID:25596134 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331
JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 decreases expression ISO Clodronic Acid results in decreased expression of SRD5A3 mRNA CTD PMID:25596134 NCBI chr14:34,554,769...34,570,423
Ensembl chr14:34,556,220...34,570,356
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Clodronic Acid results in increased expression of SRXN1 mRNA CTD PMID:25596134 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO Clodronic Acid results in decreased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Taok1 TAO kinase 1 affects expression ISO Clodronic Acid affects the expression of TAOK1 mRNA CTD PMID:25596134 NCBI chr10:62,542,870...62,630,341
Ensembl chr10:62,566,732...62,630,155
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression ISO Clodronic Acid results in decreased expression of TARS1 mRNA CTD PMID:25596134 NCBI chr 2:61,394,632...61,414,115
Ensembl chr 2:61,394,770...61,414,102
JBrowse link
G Tbxas1 thromboxane A synthase 1 affects expression ISO Clodronic Acid affects the expression of TBXAS1 mRNA CTD PMID:25596134 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Clodronic Acid results in decreased expression of TFAP2A mRNA CTD PMID:25596134 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 decreases expression ISO Clodronic Acid results in decreased expression of TFE3 mRNA CTD PMID:25596134 NCBI chr  X:15,574,579...15,587,826
Ensembl chr  X:15,575,934...15,587,419
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TGFB1 mRNA] CTD PMID:27022031 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO Clodronic Acid results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b decreases expression ISO Clodronic Acid results in decreased expression of TIMM17B mRNA CTD PMID:25596134 NCBI chr  X:15,441,369...15,448,452
Ensembl chr  X:15,441,651...15,448,403
Ensembl chr  X:15,441,651...15,448,403
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TIMP1 mRNA] CTD PMID:27022031 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO Clodronic Acid results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tmem45b transmembrane protein 45b decreases expression ISO Clodronic Acid results in decreased expression of TMEM45B mRNA CTD PMID:25596134 NCBI chr 8:32,563,872...32,609,212
Ensembl chr 8:32,563,874...32,609,212
JBrowse link
G Tmem94 transmembrane protein 94 affects expression ISO Clodronic Acid affects the expression of TMEM94 mRNA CTD PMID:25596134 NCBI chr10:104,313,691...104,320,809
Ensembl chr10:104,320,743...104,343,396
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
Clodronic Acid inhibits the reaction [Taurocholic Acid results in increased expression of TNF protein]
Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TNF mRNA]
Clodronic Acid results in increased expression of TNF mRNA
CTD PMID:20382593 PMID:25187657 PMID:27022031 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 increases expression ISO Clodronic Acid results in increased expression of TNFAIP8 mRNA CTD PMID:25596134 NCBI chr18:44,664,310...44,779,914
Ensembl chr18:44,716,226...44,779,914
JBrowse link
G Tp53 tumor protein p53 affects activity ISO Clodronic Acid affects the activity of TP53 protein CTD PMID:25596134 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Clodronic Acid results in increased expression of TP53I3 mRNA CTD PMID:25596134 NCBI chr13:75,101,759...75,145,967
Ensembl chr13:75,105,615...75,143,441
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Clodronic Acid results in increased expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tpcn1 two pore segment channel 1 increases expression ISO Clodronic Acid results in increased expression of TPCN1 mRNA CTD PMID:25596134 NCBI chr12:41,507,784...41,566,847
Ensembl chr12:41,543,696...41,566,847
JBrowse link
G Tpd52l1 TPD52 like 1 increases expression ISO Clodronic Acid results in increased expression of TPD52L1 mRNA CTD PMID:25596134 NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 affects expression ISO Clodronic Acid affects the expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:40,695,520...40,709,438
Ensembl chr12:40,695,520...40,709,462
JBrowse link
G Tspan12 tetraspanin 12 decreases expression ISO Clodronic Acid results in decreased expression of TSPAN12 mRNA CTD PMID:25596134 NCBI chr 4:48,852,823...48,953,240
Ensembl chr 4:48,852,827...48,928,372
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Clodronic Acid results in increased expression of TXN mRNA CTD PMID:25596134 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Clodronic Acid results in increased expression of TXNRD1 mRNA CTD PMID:25596134 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 increases expression ISO Clodronic Acid results in increased expression of UBE2G2 mRNA CTD PMID:25596134 NCBI chr20:11,700,089...11,721,823
Ensembl chr20:11,700,089...11,721,838
JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O decreases expression ISO Clodronic Acid results in decreased expression of UBE2O mRNA CTD PMID:25596134 NCBI chr10:105,505,721...105,553,167
Ensembl chr10:105,506,955...105,552,986
JBrowse link
G Unkl unk like zinc finger increases expression ISO Clodronic Acid results in increased expression of UNKL mRNA CTD PMID:25596134 NCBI chr10:14,547,126...14,593,090
Ensembl chr10:14,547,172...14,590,762
JBrowse link
G Vars1 valyl-tRNA synthetase 1 increases expression ISO Clodronic Acid results in increased expression of VARS1 mRNA CTD PMID:25596134 NCBI chr20:4,993,539...5,008,259
Ensembl chr20:4,993,560...5,008,262
JBrowse link
G Vegfb vascular endothelial growth factor B decreases expression ISO Clodronic Acid results in decreased expression of VEGFB mRNA CTD PMID:25596134 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644
JBrowse link
G Vim vimentin multiple interactions EXP [Clodronic Acid co-treated with Thioacetamide] results in increased expression of VIM protein CTD PMID:26957569 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 increases expression ISO Clodronic Acid results in increased expression of VTCN1 mRNA CTD PMID:25596134 NCBI chr 2:203,200,435...203,274,264
Ensembl chr 2:203,200,427...203,276,142
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 affects expression ISO Clodronic Acid affects the expression of WARS1 mRNA CTD PMID:25596134 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Wwc2 WW and C2 domain containing 2 decreases expression ISO Clodronic Acid results in decreased expression of WWC2 mRNA CTD PMID:25596134 NCBI chr16:47,368,768...47,533,816
Ensembl chr16:47,368,768...47,533,816
JBrowse link
G Xbp1 X-box binding protein 1 affects activity
decreases expression
ISO Clodronic Acid affects the activity of XBP1 protein
Clodronic Acid results in decreased expression of XBP1 mRNA
CTD PMID:25596134 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression ISO Clodronic Acid results in decreased expression of YARS1 mRNA CTD PMID:25596134 NCBI chr 5:147,375,350...147,403,578
Ensembl chr 5:147,375,350...147,403,571
JBrowse link
G Yeats2 YEATS domain containing 2 affects expression ISO Clodronic Acid affects the expression of YEATS2 mRNA CTD PMID:25596134 NCBI chr11:84,330,064...84,595,296
Ensembl chr11:84,330,064...84,583,542
JBrowse link
G Ythdc2 YTH domain containing 2 affects expression ISO Clodronic Acid affects the expression of YTHDC2 mRNA CTD PMID:25596134 NCBI chr 1:182,072,386...182,141,399
Ensembl chr 1:182,085,899...182,140,570
JBrowse link
G Zfx zinc finger protein X-linked increases expression ISO Clodronic Acid results in increased expression of ZFX mRNA CTD PMID:25596134 NCBI chr  X:63,158,368...63,204,971
Ensembl chr  X:63,158,976...63,204,530
JBrowse link
etidronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgp matrix Gla protein increases expression EXP Etidronic Acid results in increased expression of MGP mRNA CTD PMID:17270170 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Etidronic Acid results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Etidronic Acid inhibits the reaction [Polyethylene affects the secretion of TNF protein] CTD PMID:10413987 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Risedronate sodium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity EXP Risedronic Acid results in increased activity of CASP3 protein CTD PMID:19505369 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity EXP Risedronic Acid results in increased activity of CASP8 protein CTD PMID:19505369 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity EXP Risedronic Acid results in increased activity of CASP9 protein CTD PMID:19505369 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to CDC42 protein] CTD PMID:16734383 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO Risedronic Acid promotes the reaction [CSF1 protein results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]] CTD PMID:16734383 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Fdps farnesyl diphosphate synthase decreases activity
affects binding
ISO Risedronic Acid results in decreased activity of FDPS protein
Risedronic Acid binds to FDPS protein
CTD PMID:11160603 PMID:16684881 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases prenylation ISO Risedronic Acid results in decreased prenylation of HRAS protein CTD PMID:9556058 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Risedronic Acid results in increased phosphorylation of MAPK1 protein CTD PMID:18751388 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Risedronic Acid results in increased phosphorylation of MAPK3 protein CTD PMID:18751388 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Pon1 paraoxonase 1 increases activity
multiple interactions
EXP Risedronic Acid results in increased activity of PON1 protein
[Risedronic Acid results in increased activity of PON1 protein] which results in increased metabolism of homocysteine thiolactone; [Risedronic Acid results in increased activity of PON1 protein] which results in increased metabolism of Paraoxon; [Risedronic Acid results in increased activity of PON1 protein] which results in increased metabolism of phenyl acetate
CTD PMID:27387541 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Rab6a RAB6A, member RAS oncogene family decreases prenylation ISO Risedronic Acid results in decreased prenylation of RAB6A protein CTD PMID:16619218 NCBI chr 1:165,624,973...165,664,201
Ensembl chr 1:165,625,058...165,664,192
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions
decreases geranoylation
ISO Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]
Risedronic Acid promotes the reaction [CSF1 protein results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]]; Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RAC1 protein]
Risedronic Acid results in decreased geranoylation of RAC1 protein
CTD PMID:16734383 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases prenylation ISO Risedronic Acid results in decreased prenylation of RAP1A protein CTD PMID:11595616 PMID:16619218 PMID:16675582 PMID:18751388 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases localization
ISO
EXP
Risedronic Acid results in increased abundance of [Guanosine Triphosphate binds to RHOA protein]
Risedronic Acid results in increased localization of RHOA protein
CTD PMID:16734383 PMID:19505369 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
zoledronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) increases expression ISO zoledronic acid results in increased expression of A4GALT mRNA CTD PMID:24714768 NCBI chr 7:124,085,832...124,110,440
Ensembl chr 7:124,085,834...124,089,385
JBrowse link
G Aadat aminoadipate aminotransferase decreases expression ISO zoledronic acid results in decreased expression of AADAT mRNA CTD PMID:24714768 NCBI chr16:32,832,001...32,868,680
Ensembl chr16:32,832,061...32,868,702
JBrowse link
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Zoledronic Acid results in decreased expression of AARS1 mRNA CTD PMID:25596134 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO zoledronic acid results in increased expression of ABCA12 mRNA CTD PMID:24714768 NCBI chr 9:78,521,477...78,693,421
Ensembl chr 9:78,522,464...78,693,028
JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 increases expression ISO zoledronic acid results in increased expression of ABCA4 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 2:225,645,539...225,783,288
Ensembl chr 2:225,645,568...225,783,287
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 decreases expression ISO zoledronic acid results in decreased expression of ABCB6 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases expression ISO zoledronic acid results in decreased expression of ABCC5 mRNA CTD PMID:24714768 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO zoledronic acid results in increased expression of ABCG2 mRNA CTD PMID:18225567 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd17c abhydrolase domain containing 17C, depalmitoylase decreases expression ISO zoledronic acid results in decreased expression of ABHD17C mRNA CTD PMID:24714768 NCBI chr 1:146,248,505...146,289,465
Ensembl chr 1:146,248,503...146,289,465
JBrowse link
G Abi3bp ABI family member 3 binding protein decreases expression ISO zoledronic acid results in decreased expression of ABI3BP mRNA CTD PMID:24714768 NCBI chr11:46,206,932...46,422,791
Ensembl chr11:46,208,075...46,369,577
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression ISO zoledronic acid results in decreased expression of ACAA1 mRNA CTD PMID:28871336 NCBI chr 8:127,836,235...127,845,296 JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain decreases expression ISO zoledronic acid results in decreased expression of ACADL mRNA CTD PMID:28871336 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO zoledronic acid results in decreased expression of ACADM mRNA CTD PMID:28871336 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression ISO zoledronic acid results in increased expression of ACAT2 mRNA CTD PMID:24714768 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acbd4 acyl-CoA binding domain containing 4 decreases expression ISO zoledronic acid results in decreased expression of ACBD4 mRNA CTD PMID:20977926 NCBI chr10:91,186,131...91,200,081
Ensembl chr10:91,187,593...91,196,572
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression ISO zoledronic acid results in decreased expression of ACMSD mRNA CTD PMID:24714768 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of ACOX1 mRNA; zoledronic acid results in decreased expression of ACOX1 protein
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of ACOX1 mRNA]
CTD PMID:28871336 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acox2 acyl-CoA oxidase 2 multiple interactions
decreases expression
ISO Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA] CTD PMID:28871336 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acp3 acid phosphatase 3 decreases expression ISO Zoledronic Acid results in decreased expression of ACP3 mRNA CTD PMID:24714768 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Zoledronic Acid results in decreased expression of ACSL1 mRNA; Zoledronic Acid results in decreased expression of ACSL1 protein CTD PMID:25596134 PMID:28871336 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO zoledronic acid results in decreased expression of ACSL3 protein CTD PMID:28871336 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression ISO zoledronic acid results in increased expression of ACSL5 mRNA CTD PMID:24714768 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO zoledronic acid results in decreased expression of ACSM3 mRNA CTD PMID:24714768 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO zoledronic acid results in increased expression of ACSS2 mRNA CTD PMID:24714768 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO zoledronic acid results in increased expression of ACTA2 protein
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]
CTD PMID:28871336 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO zoledronic acid results in increased expression of ACTBL2 mRNA CTD PMID:24714768 NCBI chr 2:42,829,413...42,832,160
Ensembl chr 2:42,829,413...42,832,160
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO zoledronic acid results in decreased expression of ACTG2 mRNA CTD PMID:24714768 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Actn1 actinin, alpha 1 decreases expression ISO zoledronic acid results in decreased expression of ACTN1 protein CTD PMID:28871336 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn4 actinin alpha 4 decreases expression ISO zoledronic acid results in decreased expression of ACTN4 protein CTD PMID:28871336 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions
increases expression
decreases activity
ISO ADAM17 protein promotes the reaction [zoledronic acid results in decreased expression of TNFSF11 protein]
zoledronic acid results in increased expression of ADAM17 protein
zoledronic acid results in decreased activity of ADAM17 protein
CTD PMID:14753746 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression ISO zoledronic acid results in decreased expression of ADAM19 mRNA CTD PMID:24714768 NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 increases expression ISO zoledronic acid results in increased expression of ADAM28 mRNA CTD PMID:24714768 NCBI chr15:50,356,745...50,425,911
Ensembl chr15:50,358,192...50,425,900
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression ISO zoledronic acid results in increased expression of ADAMTS1 mRNA CTD PMID:24714768 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression ISO zoledronic acid results in increased expression of ADAMTS9 mRNA CTD PMID:24714768 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adamtsl3 ADAMTS-like 3 decreases expression ISO zoledronic acid results in decreased expression of ADAMTSL3 mRNA CTD PMID:24714768 NCBI chr 1:144,238,958...144,561,065
Ensembl chr 1:144,239,020...144,561,247
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 increases expression ISO zoledronic acid results in increased expression of ADGRF1 mRNA CTD PMID:24714768 NCBI chr 9:20,343,730...20,378,686 JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO zoledronic acid results in decreased expression of ADGRG1 mRNA CTD PMID:24714768 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 decreases expression ISO zoledronic acid results in decreased expression of ADGRL1 mRNA CTD PMID:20977926 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 increases expression ISO zoledronic acid results in increased expression of ADGRV1 mRNA CTD PMID:24714768 NCBI chr 2:8,926,843...9,504,455
Ensembl chr 2:8,926,850...9,504,134
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) decreases expression ISO zoledronic acid results in decreased expression of ADH6 mRNA CTD PMID:24714768 NCBI chr 2:243,656,568...243,687,857
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adm2 adrenomedullin 2 decreases expression ISO zoledronic acid results in decreased expression of ADM2 mRNA CTD PMID:24714768 NCBI chr 7:130,296,895...130,298,641
Ensembl chr 7:130,296,897...130,298,644
JBrowse link
G Adsl adenylosuccinate lyase decreases expression ISO zoledronic acid results in decreased expression of ADSL mRNA CTD PMID:20977926 NCBI chr 7:122,157,201...122,192,328
Ensembl chr 7:122,157,201...122,192,328
JBrowse link
G Afp alpha-fetoprotein increases expression ISO zoledronic acid results in increased expression of AFP protein CTD PMID:28871336 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 increases expression ISO zoledronic acid results in increased expression of AGPAT5 mRNA CTD PMID:24714768 NCBI chr16:75,812,837...75,855,996
Ensembl chr16:75,812,997...75,855,745
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member decreases expression ISO zoledronic acid results in decreased expression of AGR2 mRNA CTD PMID:24714768 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Agrn agrin increases expression ISO zoledronic acid results in increased expression of AGRN protein CTD PMID:28871336 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 decreases expression ISO zoledronic acid results in decreased expression of AHNAK2 mRNA CTD PMID:24714768 NCBI chr 6:137,335,273...137,380,219 JBrowse link
G Ahr aryl hydrocarbon receptor affects activity ISO zoledronic acid affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression ISO zoledronic acid results in increased expression of AHSG protein CTD PMID:28871336 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO zoledronic acid results in decreased expression of AK3 mRNA CTD PMID:25596134 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Ak5 adenylate kinase 5 decreases expression ISO zoledronic acid results in decreased expression of AK5 mRNA CTD PMID:24714768 NCBI chr 2:257,671,772...257,864,385
Ensembl chr 2:257,671,772...257,864,385
JBrowse link
G Akap7 A-kinase anchoring protein 7 decreases expression ISO zoledronic acid results in decreased expression of AKAP7 mRNA CTD PMID:24714768 NCBI chr 1:21,129,213...21,263,850
Ensembl chr 1:21,141,970...21,263,850
JBrowse link
G Akip1 A-kinase interacting protein 1 increases expression ISO zoledronic acid results in increased expression of AKIP1 mRNA CTD PMID:24714768 NCBI chr 1:174,330,628...174,339,494
Ensembl chr 1:174,330,695...174,339,494
JBrowse link
G Akirin2 akirin 2 decreases expression ISO zoledronic acid results in decreased expression of AKIRIN2 mRNA CTD PMID:20977926 NCBI chr 5:50,001,945...50,016,544
Ensembl chr 5:50,002,184...50,016,539
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression ISO zoledronic acid results in increased expression of AKR1A1 mRNA CTD PMID:24714768 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO zoledronic acid results in increased expression of AKR1B1 mRNA CTD PMID:24714768 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO zoledronic acid results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:19530242 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt1s1 AKT1 substrate 1 increases expression ISO zoledronic acid results in increased expression of AKT1S1 mRNA CTD PMID:20977926 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Alb albumin increases expression ISO zoledronic acid results in increased expression of ALB protein CTD PMID:28871336 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO zoledronic acid results in decreased expression of ALDH18A1 mRNA CTD PMID:25596134 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO zoledronic acid results in increased expression of ALDH1A3 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression ISO zoledronic acid results in decreased expression of ALDH3A2 mRNA CTD PMID:24714768 NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 increases expression ISO zoledronic acid results in increased expression of ALDH8A1 mRNA CTD PMID:24714768 NCBI chr 1:16,910,043...16,929,465
Ensembl chr 1:16,910,069...16,930,481
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO zoledronic acid results in increased expression of ALOX5 mRNA CTD PMID:24714768 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO zoledronic acid results in increased expression of ALOX5AP mRNA CTD PMID:20977926 PMID:24714768 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO zoledronic acid results in increased expression of ALPK2 mRNA CTD PMID:24714768 NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases activity
multiple interactions
ISO zoledronic acid results in decreased activity of ALPL protein
TNFRSF11B protein affects the reaction [zoledronic acid results in decreased activity of ALPL protein]
CTD PMID:18496637 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Als2cl ALS2 C-terminal like increases expression ISO zoledronic acid results in increased expression of ALS2CL mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 8:119,156,081...119,176,680
Ensembl chr 8:119,160,731...119,174,830
JBrowse link
G Ank2 ankyrin 2 decreases expression ISO zoledronic acid results in decreased expression of ANK2 mRNA CTD PMID:24714768 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ankef1 ankyrin repeat and EF-hand domain containing 1 increases expression ISO zoledronic acid results in increased expression of ANKEF1 mRNA CTD PMID:20977926 NCBI chr 3:129,462,446...129,536,423
Ensembl chr 3:129,501,105...129,536,422
JBrowse link
G Ankra2 ankyrin repeat family A member 2 increases expression ISO zoledronic acid results in increased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr  X:82,407,601...82,418,229
Ensembl chr  X:82,407,598...82,418,425
Ensembl chr 2:82,407,598...82,418,425
JBrowse link
G Ankrd10 ankyrin repeat domain 10 increases expression ISO zoledronic acid results in increased expression of ANKRD10 mRNA CTD PMID:20977926 NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194
JBrowse link
G Ankrd22 ankyrin repeat domain 22 increases expression ISO zoledronic acid results in increased expression of ANKRD22 mRNA CTD PMID:24714768 NCBI chr 1:252,430,750...252,461,346
Ensembl chr 1:252,429,677...252,461,461
JBrowse link
G Anln anillin, actin binding protein decreases expression ISO zoledronic acid results in decreased expression of ANLN mRNA CTD PMID:24714768 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773
JBrowse link
G Anpep alanyl aminopeptidase, membrane increases expression ISO zoledronic acid results in increased expression of ANPEP mRNA CTD PMID:24714768 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Anxa2 annexin A2 decreases expression ISO zoledronic acid results in decreased expression of ANXA2 protein CTD PMID:28871336 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 increases expression ISO zoledronic acid results in increased expression of AP1S2 mRNA CTD PMID:24714768 NCBI chr  X:32,329,883...32,376,301
Ensembl chr  X:32,329,598...32,355,307
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 increases expression ISO zoledronic acid results in increased expression of AP1S3 mRNA CTD PMID:20977926 NCBI chr 9:85,386,752...85,445,977
Ensembl chr 9:85,387,065...85,445,939
JBrowse link
G Ap4b1 adaptor related protein complex 4 subunit beta 1 increases expression ISO zoledronic acid results in increased expression of AP4B1 mRNA CTD PMID:24714768 NCBI chr 2:206,293,679...206,305,705
Ensembl chr 2:206,293,720...206,305,702
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO zoledronic acid results in increased expression of APAF1 mRNA CTD PMID:28871336 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apba3 amyloid beta precursor protein binding family A member 3 decreases expression ISO zoledronic acid results in decreased expression of APBA3 mRNA CTD PMID:20977926 NCBI chr 7:11,314,468...11,319,540
Ensembl chr 7:11,314,424...11,319,516
JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit increases expression ISO zoledronic acid results in increased expression of APH1A mRNA CTD PMID:20977926 NCBI chr 2:198,006,247...198,009,837
Ensembl chr 2:198,006,316...198,009,830
JBrowse link
G Api5 apoptosis inhibitor 5 increases expression ISO zoledronic acid results in increased expression of API5 mRNA CTD PMID:20977926 NCBI chr 3:83,310,878...83,336,053
Ensembl chr 3:83,310,884...83,335,960
JBrowse link
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 decreases expression ISO zoledronic acid results in decreased expression of ARAP1 mRNA CTD PMID:20977926 NCBI chr 1:166,459,062...166,525,200
Ensembl chr 1:166,478,005...166,525,255
JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO zoledronic acid results in decreased expression of ARHGAP18 mRNA CTD PMID:20977926 NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301
JBrowse link
G Arhgap19 Rho GTPase activating protein 19 decreases expression ISO zoledronic acid results in decreased expression of ARHGAP19 mRNA CTD PMID:20977926 NCBI chr 1:261,015,083...261,051,515
Ensembl chr 1:261,015,123...261,051,498
JBrowse link
G Arhgap22 Rho GTPase activating protein 22 increases expression ISO zoledronic acid results in increased expression of ARHGAP22 mRNA CTD PMID:24714768 NCBI chr16:9,454,269...9,613,508
Ensembl chr16:9,486,832...9,613,528
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression ISO zoledronic acid results in decreased expression of ARHGAP24 mRNA CTD PMID:24714768 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
JBrowse link
G Arhgap26 Rho GTPase activating protein 26 increases expression ISO zoledronic acid results in increased expression of ARHGAP26 mRNA CTD PMID:24714768 NCBI chr18:31,807,052...32,557,176
Ensembl chr18:31,812,109...32,207,801
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGAP29 mRNA CTD PMID:16996129 NCBI chr 2:225,552,075...225,613,349
Ensembl chr 2:225,552,148...225,613,359
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO zoledronic acid results in decreased expression of ARHGDIA protein CTD PMID:28871336 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arhgef12 Rho guanine nucleotide exchange factor 12 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGEF12 mRNA CTD PMID:16996129 NCBI chr 8:47,259,377...47,393,042
Ensembl chr 8:47,259,404...47,393,503
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGEF3 mRNA CTD PMID:16996129 NCBI chr16:2,743,714...3,026,768
Ensembl chr16:2,743,823...3,026,760
JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 decreases expression ISO zoledronic acid results in decreased expression of ARHGEF4 mRNA CTD PMID:24714768 NCBI chr 9:41,160,562...41,305,015
Ensembl chr 9:41,295,909...41,302,501
JBrowse link
G Arid2 AT-rich interaction domain 2 decreases expression ISO zoledronic acid results in decreased expression of ARID2 mRNA CTD PMID:20977926 NCBI chr 7:137,680,564...137,798,329
Ensembl chr 7:137,680,530...137,795,655
JBrowse link
G Arl14 ADP-ribosylation factor like GTPase 14 decreases expression ISO zoledronic acid results in decreased expression of ARL14 mRNA CTD PMID:24714768 NCBI chr 2:165,835,196...165,836,291
Ensembl chr 2:165,835,701...165,836,279
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C decreases expression ISO zoledronic acid results in decreased expression of ARL4C mRNA CTD PMID:24714768 NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094
JBrowse link
G Arl5b ADP-ribosylation factor like GTPase 5B increases expression ISO zoledronic acid results in increased expression of ARL5B mRNA CTD PMID:20977926 NCBI chr17:82,065,893...82,092,693
Ensembl chr17:82,065,937...82,091,362
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 decreases expression ISO zoledronic acid results in decreased expression of ARNT2 mRNA CTD PMID:24714768 NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like increases expression ISO zoledronic acid results in increased expression of ARNTL mRNA CTD PMID:20977926 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO zoledronic acid results in increased expression of ARRDC3 mRNA CTD PMID:24714768 NCBI chr 2:8,732,907...8,745,445
Ensembl chr 2:8,732,932...8,743,069
JBrowse link
G Arrdc4 arrestin domain containing 4 increases expression ISO zoledronic acid results in increased expression of ARRDC4 mRNA CTD PMID:24714768 NCBI chr 1:129,766,097...129,780,076
Ensembl chr 1:129,766,100...129,780,356
JBrowse link
G Asic1 acid sensing ion channel subunit 1 multiple interactions
decreases expression
ISO
EXP
zoledronic acid inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA]
zoledronic acid results in decreased expression of ASIC1 mRNA
CTD PMID:16769263 PMID:17323179 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO zoledronic acid results in decreased expression of ASNS mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asphd2 aspartate beta-hydroxylase domain containing 2 decreases expression ISO zoledronic acid results in decreased expression of ASPHD2 mRNA CTD PMID:24714768 NCBI chr12:50,269,347...50,279,855
Ensembl chr12:50,269,347...50,279,745
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression ISO zoledronic acid results in decreased expression of ASPM mRNA CTD PMID:24714768 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO zoledronic acid results in decreased expression of ATF4 mRNA CTD PMID:24714768 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO zoledronic acid results in increased expression of ATF5 mRNA CTD PMID:24714768 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atg2a autophagy related 2A increases expression ISO zoledronic acid results in increased expression of ATG2A protein CTD PMID:28871336 NCBI chr 1:221,612,584...221,632,291
Ensembl chr 1:221,612,584...221,632,267
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 increases expression ISO zoledronic acid results in increased expression of ATOH8 mRNA CTD PMID:24714768 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517
JBrowse link
G Atp10b ATPase phospholipid transporting 10B (putative) increases expression ISO zoledronic acid results in increased expression of ATP10B mRNA CTD PMID:24714768 NCBI chr10:28,449,248...28,862,423
Ensembl chr10:28,449,335...28,864,255
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression ISO zoledronic acid results in decreased expression of ATP1A1 mRNA CTD PMID:24714768 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 decreases expression ISO zoledronic acid results in decreased expression of ATP6V0A4 mRNA CTD PMID:24714768 NCBI chr 4:65,736,585...65,821,916
Ensembl chr 4:65,736,585...65,818,521
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 decreases expression ISO zoledronic acid results in decreased expression of ATP6V1B1 mRNA CTD PMID:24714768 NCBI chr 4:115,417,100...115,435,754
Ensembl chr 4:115,416,580...115,437,206
JBrowse link
G Atp7b ATPase copper transporting beta decreases expression ISO zoledronic acid results in decreased expression of ATP7B mRNA CTD PMID:24714768 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression ISO zoledronic acid results in decreased expression of ATRX mRNA CTD PMID:20977926 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Atxn1 ataxin 1 increases expression ISO zoledronic acid results in increased expression of ATXN1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814
JBrowse link
G Aurkb aurora kinase B decreases expression ISO zoledronic acid results in decreased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Avpi1 arginine vasopressin-induced 1 decreases expression ISO zoledronic acid results in decreased expression of AVPI1 mRNA CTD PMID:24714768 NCBI chr 1:261,365,590...261,371,519
Ensembl chr 1:261,365,590...261,371,508
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression ISO zoledronic acid results in decreased expression of AXL mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G B3galt5 Beta-1,3-galactosyltransferase 5 decreases expression ISO zoledronic acid results in decreased expression of B3GALT5 mRNA CTD PMID:24714768 NCBI chr11:36,638,067...36,683,915
Ensembl chr11:36,634,662...36,683,672
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase increases expression ISO zoledronic acid results in increased expression of BAAT mRNA CTD PMID:24714768 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression
ISO [Tretinoin co-treated with zoledronic acid] results in increased expression of BAD protein
zoledronic acid results in increased expression of BAD mRNA
CTD PMID:19036117 PMID:20349282 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag1 BAG cochaperone 1 increases expression ISO zoledronic acid results in increased expression of BAG1 mRNA CTD PMID:19036117 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO zoledronic acid results in increased expression of BAG3 mRNA CTD PMID:19036117 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO zoledronic acid results in increased expression of BASP1 mRNA CTD PMID:24714768 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions
ISO zoledronic acid results in decreased expression of BAX mRNA
zoledronic acid results in increased expression of BAX mRNA
[zoledronic acid co-treated with Doxorubicin] results in increased expression of BAX protein
[Tretinoin co-treated with zoledronic acid] results in increased expression of BAX protein
CTD PMID:19036117 PMID:19789217 PMID:20349282 PMID:28871336 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbln bublin coiled coil protein increases expression ISO Zoledronic Acid results in increased expression of BBLN mRNA CTD PMID:24714768 NCBI chr 3:11,408,076...11,410,907
Ensembl chr 3:11,408,348...11,410,732
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO zoledronic acid results in decreased expression of BBOX1 mRNA CTD PMID:24714768 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Bbx BBX high mobility group box domain containing decreases expression ISO zoledronic acid results in decreased expression of BBX mRNA CTD PMID:20977926 NCBI chr11:52,983,286...53,228,557
Ensembl chr11:53,081,025...53,228,716
JBrowse link
G Bcap29 B-cell receptor-associated protein 29 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of BCAP29 mRNA CTD PMID:16996129 NCBI chr 6:50,883,758...50,923,743
Ensembl chr 6:50,883,787...50,923,510
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member decreases expression ISO Zoledronic Acid results in decreased expression of BCAR3 mRNA CTD PMID:25596134 NCBI chr 2:226,563,050...226,679,449
Ensembl chr 2:226,563,050...226,679,438
JBrowse link
G Bche butyrylcholinesterase decreases expression ISO zoledronic acid results in decreased expression of BCHE mRNA CTD PMID:24714768 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
decreases expression
multiple interactions
increases expression
affects expression
ISO BCL2 protein results in decreased susceptibility to zoledronic acid
zoledronic acid results in decreased expression of BCL2 mRNA
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of BCL2 protein
zoledronic acid results in increased expression of BCL2 mRNA
zoledronic acid affects the expression of BCL2 mRNA
[Tretinoin co-treated with zoledronic acid] results in decreased expression of BCL2 protein; [zoledronic acid co-treated with docetaxel] results in decreased expression of BCL2 protein
CTD PMID:11986784 PMID:18225567 PMID:19036117 PMID:19103299 PMID:19789217 PMID:20349282 PMID:24714768 PMID:28871336 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO zoledronic acid results in decreased expression of BCL2A1 mRNA CTD PMID:19036117 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO zoledronic acid results in increased expression of BCL2L1 mRNA CTD PMID:19036117 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l10 BCL2 like 10 affects expression ISO zoledronic acid affects the expression of BCL2L10 mRNA CTD PMID:19036117 NCBI chr 8:82,288,705...82,294,750
Ensembl chr 8:82,288,705...82,294,744
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of BCL2L11 mRNA CTD PMID:16996129 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bcl2l15 BCL2-like 15 increases expression ISO zoledronic acid results in increased expression of BCL2L15 mRNA CTD PMID:24714768 NCBI chr 2:206,307,778...206,319,662
Ensembl chr 2:206,314,213...206,319,332
JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO zoledronic acid results in increased expression of BCL2L2 mRNA CTD PMID:19036117 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Becn1 beclin 1 decreases expression ISO zoledronic acid results in decreased expression of BECN1 protein CTD PMID:28871336 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bend5 BEN domain containing 5 decreases expression ISO zoledronic acid results in decreased expression of BEND5 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 5:131,257,127...131,312,335
Ensembl chr 5:131,257,127...131,312,335
JBrowse link
G Bfsp1 beaded filament structural protein 1 decreases expression ISO zoledronic acid results in decreased expression of BFSP1 mRNA CTD PMID:24714768 NCBI chr 3:137,935,345...137,992,652
Ensembl chr 3:137,935,345...137,969,658
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO zoledronic acid results in increased expression of BGLAP mRNA CTD PMID:14751568 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of BHLHE40 mRNA CTD PMID:16996129 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bicdl1 BICD family like cargo adaptor 1 increases expression ISO zoledronic acid results in increased expression of BICDL1 mRNA CTD PMID:20977926 NCBI chr12:46,615,597...46,703,287
Ensembl chr12:46,615,649...46,703,287
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO zoledronic acid results in increased expression of BID mRNA CTD PMID:19036117 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions
decreases expression
ISO [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC2 mRNA
zoledronic acid results in decreased expression of BIRC2 mRNA
CTD PMID:19036117 PMID:20349282 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO zoledronic acid results in increased expression of BIRC3 mRNA CTD PMID:24714768 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 mRNA; [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 protein
zoledronic acid results in decreased expression of BIRC5 mRNA; zoledronic acid results in decreased expression of BIRC5 protein
CTD PMID:19036117 PMID:20349282 PMID:24714768 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 decreases expression ISO zoledronic acid results in decreased expression of BIRC6 mRNA CTD PMID:19036117 NCBI chr 6:21,900,763...22,092,484
Ensembl chr 6:21,950,100...22,092,346
JBrowse link
G Bivm basic, immunoglobulin-like variable motif containing decreases expression ISO zoledronic acid results in decreased expression of BIVM mRNA CTD PMID:24714768 NCBI chr 9:50,884,888...50,921,133
Ensembl chr 9:50,892,605...50,919,791
JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex 1 subunit 5 increases expression ISO zoledronic acid results in increased expression of BLOC1S5 mRNA CTD PMID:20977926 NCBI chr17:26,808,193...26,833,257
Ensembl chr17:26,808,330...26,833,247
JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO zoledronic acid results in increased expression of BMF mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bmp1 bone morphogenetic protein 1 increases expression ISO zoledronic acid results in increased expression of BMP1 mRNA CTD PMID:20977926 NCBI chr15:52,166,401...52,210,786
Ensembl chr15:52,166,401...52,210,746
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO zoledronic acid results in increased expression of BMP2 mRNA CTD PMID:14751568 PMID:24714768 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A increases expression ISO zoledronic acid results in increased expression of BMPR1A mRNA CTD PMID:24714768 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 increases expression ISO zoledronic acid results in increased expression of BMPR2 mRNA CTD PMID:20977926 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of BNIP3 mRNA
zoledronic acid results in increased expression of BNIP3 mRNA
CTD PMID:19036117 PMID:25596134 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bnip5 BCL2 interacting protein 5 increases expression ISO Zoledronic Acid results in increased expression of BNIP5 mRNA CTD PMID:24714768 NCBI chr20:6,150,811...6,164,148
Ensembl chr20:6,150,814...6,160,963
JBrowse link
G Bola2 bolA family member 2 increases expression ISO zoledronic acid results in increased expression of BOLA2 mRNA CTD PMID:24714768 NCBI chr 1:198,120,104...198,121,158
Ensembl chr 1:198,120,099...198,121,158
JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO zoledronic acid results in increased expression of BPGM mRNA CTD PMID:24714768 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO zoledronic acid results in increased expression of BRCA2 mRNA CTD PMID:20977926 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Brip1 BRCA1 interacting helicase 1 increases expression ISO zoledronic acid results in increased expression of BRIP1 mRNA CTD PMID:20977926 NCBI chr10:73,507,009...73,632,742
Ensembl chr10:73,507,100...73,629,581
JBrowse link
G Btbd11 BTB domain containing 11 decreases expression ISO zoledronic acid results in decreased expression of BTBD11 mRNA CTD PMID:24714768 NCBI chr 7:24,041,194...24,314,418
Ensembl chr 7:24,043,126...24,313,885
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of BTG2 mRNA
zoledronic acid results in increased expression of BTG2 mRNA
CTD PMID:20977926 PMID:25596134 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of BUB1 mRNA CTD PMID:16996129 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G C1ql4 complement C1q like 4 decreases expression ISO zoledronic acid results in decreased expression of C1QL4 mRNA CTD PMID:24714768 NCBI chr 7:140,766,517...140,771,415
Ensembl chr 7:140,767,737...140,770,647
JBrowse link
G C1qtnf1 C1q and TNF related 1 increases expression ISO zoledronic acid results in increased expression of C1QTNF1 mRNA CTD PMID:24714768 NCBI chr10:107,455,845...107,477,160
Ensembl chr10:107,455,845...107,477,162
JBrowse link
G C1qtnf6 C1q and TNF related 6 decreases expression ISO zoledronic acid results in decreased expression of C1QTNF6 mRNA CTD PMID:24714768 NCBI chr 7:119,746,150...119,752,727
Ensembl chr 7:119,746,118...119,753,290
JBrowse link
G C1r complement C1r increases expression ISO zoledronic acid results in increased expression of C1R mRNA CTD PMID:24714768 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
JBrowse link
G C1s complement C1s increases expression ISO zoledronic acid results in increased expression of C1S mRNA CTD PMID:24714768 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
JBrowse link
G C2cd4a C2 calcium-dependent domain containing 4A increases expression ISO zoledronic acid results in increased expression of C2CD4A mRNA CTD PMID:24714768 NCBI chr 8:73,671,516...73,686,344
Ensembl chr 8:73,672,295...73,673,317
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression ISO zoledronic acid results in increased expression of NLF2 mRNA CTD PMID:24714768 NCBI chr 8:73,555,414...73,580,848
Ensembl chr 8:73,593,310...73,594,332
JBrowse link
G C3 complement C3 increases expression ISO zoledronic acid results in increased expression of C3 mRNA CTD PMID:24714768 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4bpa complement component 4 binding protein, alpha increases expression ISO zoledronic acid results in increased expression of C4BPA mRNA CTD PMID:24714768 NCBI chr13:47,342,090...47,377,580
Ensembl chr13:47,342,079...47,377,703
JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 increases expression ISO zoledronic acid results in increased expression of CACNA2D3 mRNA CTD PMID:24714768 NCBI chr16:4,871,348...5,795,825
Ensembl chr16:4,871,650...5,795,825
JBrowse link
G Cactin cactin, spliceosome C complex subunit decreases expression ISO zoledronic acid results in decreased expression of CACTIN protein CTD PMID:28871336 NCBI chr 7:11,258,526...11,266,509
Ensembl chr 7:11,261,201...11,266,630
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO zoledronic acid results in decreased expression of CALM1 protein CTD PMID:28871336 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calml4 calmodulin-like 4 decreases expression ISO zoledronic acid results in decreased expression of CALML4 mRNA CTD PMID:20977926 NCBI chr 8:67,753,279...67,765,359
Ensembl chr 8:67,753,279...67,765,358
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression ISO zoledronic acid results in increased expression of CAMK1D mRNA CTD PMID:24714768 NCBI chr17:76,532,611...76,938,956
Ensembl chr17:76,532,611...76,938,956
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression ISO zoledronic acid results in decreased expression of CAMK2D mRNA CTD PMID:24714768 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 decreases expression ISO zoledronic acid results in decreased expression of CAMK2N1 mRNA CTD PMID:24714768 NCBI chr 5:156,876,706...156,878,486
Ensembl chr 5:156,876,706...156,878,486
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression ISO zoledronic acid results in decreased expression of CAMK4 protein CTD PMID:28871336 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 decreases expression ISO zoledronic acid results in decreased expression of CAMSAP1 protein CTD PMID:28871336 NCBI chr 3:3,373,971...3,434,027
Ensembl chr 3:3,373,971...3,434,027
JBrowse link
G Cant1 calcium activated nucleotidase 1 increases expression ISO zoledronic acid results in increased expression of CANT1 mRNA CTD PMID:20977926 NCBI chr10:107,432,500...107,445,634
Ensembl chr10:107,432,506...107,445,522
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 decreases expression ISO zoledronic acid results in decreased expression of CAP2 mRNA CTD PMID:24714768 NCBI chr17:18,441,614...18,592,866
Ensembl chr17:18,442,127...18,592,750
JBrowse link
G Capn13 calpain 13 increases expression ISO zoledronic acid results in increased expression of CAPN13 mRNA CTD PMID:24714768 NCBI chr 6:24,579,590...24,676,536
Ensembl chr 6:24,579,622...24,676,524
JBrowse link
G Capn6 calpain 6 decreases expression ISO zoledronic acid results in decreased expression of CAPN6 mRNA CTD PMID:24714768 NCBI chr  X:115,049,113...115,073,824
Ensembl chr  X:115,049,154...115,073,890
JBrowse link
G Caprin1 cell cycle associated protein 1 increases expression ISO zoledronic acid results in increased expression of CAPRIN1 mRNA CTD PMID:20977926 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Card10 caspase recruitment domain family, member 10 decreases expression ISO zoledronic acid results in decreased expression of CARD10 mRNA CTD PMID:24714768 NCBI chr 7:119,998,639...120,028,632
Ensembl chr 7:119,999,472...120,027,026
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO Zoledronic Acid results in increased expression of CARS1 mRNA CTD PMID:20977926 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp1 caspase 1 affects expression
increases expression
multiple interactions
ISO zoledronic acid affects the expression of CASP1 mRNA
zoledronic acid results in increased expression of CASP1 mRNA
[zoledronic acid co-treated with fluvastatin] results in increased expression of CASP1 mRNA
CTD PMID:16996129 PMID:19036117 PMID:24714768 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp14 caspase 14 decreases expression ISO zoledronic acid results in decreased expression of CASP14 mRNA CTD PMID:19036117 NCBI chr 7:13,938,376...13,944,286
Ensembl chr 7:13,938,302...13,945,130
JBrowse link
G Casp2 caspase 2 affects expression ISO zoledronic acid affects the expression of CASP2 mRNA CTD PMID:19036117 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
increases activity
decreases expression
ISO [Tretinoin co-treated with zoledronic acid] results in increased activity of CASP3 protein; [vorinostat co-treated with zoledronic acid] results in increased activity of CASP3 protein; [zoledronic acid co-treated with arsenic trioxide] results in increased cleavage of CASP3 protein; [zoledronic acid co-treated with docetaxel] results in decreased expression of CASP3 protein; [zoledronic acid co-treated with Doxorubicin] results in increased expression of CASP3 protein; [zoledronic acid co-treated with Gossypol] results in increased activity of CASP3 protein; vorinostat promotes the reaction [zoledronic acid results in increased activity of CASP3 protein]; zoledronic acid results in increased cleavage of and results in increased activity of CASP3 protein; zoledronic acid results in increased expression of and results in increased activity of CASP3 protein
zoledronic acid results in increased expression of CASP3 mRNA
zoledronic acid results in increased cleavage of CASP3 protein
[zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP3 protein
zoledronic acid results in decreased expression of CASP3 protein
CTD PMID:11986784 PMID:12796698 PMID:17070308 PMID:17562444 PMID:18025282 PMID:18695136 PMID:19036117 PMID:19789217 PMID:19825521 PMID:19915386 PMID:20349282 PMID:20977926 PMID:24714768 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 increases activity ISO zoledronic acid results in increased activity of CASP6 protein CTD PMID:17070308 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO [Tretinoin co-treated with Zoledronic Acid] results in increased activity of CASP7 protein; [Zoledronic Acid co-treated with Gossypol] results in increased activity of CASP7 protein
zoledronic acid results in increased activity of CASP7 protein
CTD PMID:19825521 PMID:20349282 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
ISO zoledronic acid results in increased expression of CASP8 mRNA
[zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP8 protein
CTD PMID:19036117 PMID:19789217 PMID:20977926 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
ISO zoledronic acid results in increased activity of CASP9 protein
zoledronic acid results in increased cleavage of and results in increased activity of CASP9 protein
[zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP9 protein
CTD PMID:12799645 PMID:19036117 PMID:19789217 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casr calcium-sensing receptor decreases expression ISO zoledronic acid results in decreased expression of CASR mRNA CTD PMID:24714768 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 increases expression ISO zoledronic acid results in increased expression of CASTOR1 mRNA CTD PMID:24714768 NCBI chr14:84,447,552...84,457,396
Ensembl chr14:84,447,885...84,452,367
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO zoledronic acid results in decreased expression of CAVIN2 mRNA CTD PMID:24714768 NCBI chr 9:55,244,136...55,256,153
Ensembl chr 9:55,243,255...55,256,340
JBrowse link
G Cbr1 carbonyl reductase 1 decreases expression ISO zoledronic acid results in decreased expression of CBR1 mRNA CTD PMID:24714768 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cbs cystathionine beta synthase decreases expression ISO zoledronic acid results in decreased expression of CBS mRNA CTD PMID:24714768 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Cbx5 chromobox 5 increases expression ISO zoledronic acid results in increased expression of CBX5 mRNA CTD PMID:20977926 NCBI chr 7:144,819,673...144,865,014
Ensembl chr 7:144,819,420...144,837,583
JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO zoledronic acid results in decreased expression of CC2D2A mRNA CTD PMID:24714768 NCBI chr14:71,895,128...71,979,452
Ensembl chr14:71,895,246...71,973,419
JBrowse link
G Ccdc138 coiled-coil domain containing 138 increases expression ISO zoledronic acid results in increased expression of CCDC138 mRNA CTD PMID:20977926 NCBI chr20:28,076,784...28,158,053
Ensembl chr20:28,078,500...28,157,071
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO zoledronic acid promotes the reaction [Gossypol results in decreased expression of CCL2 mRNA]
zoledronic acid results in increased expression of CCL2 mRNA
CTD PMID:19825521 PMID:24714768 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO zoledronic acid results in increased expression of CCL20 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 increases expression ISO zoledronic acid results in increased expression of CCL28 mRNA CTD PMID:24714768 NCBI chr 2:52,379,341...52,403,979
Ensembl chr 2:52,379,341...52,404,246
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 increases expression ISO Zoledronic Acid results in increased expression of CCL23 mRNA CTD PMID:24714768 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
decreases expression
ISO CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in increased expression of CDKN1A protein]; geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of CCN1 protein]; Zoledronic Acid promotes the reaction [CCN1 protein affects the expression of CDKN1B protein]
Zoledronic Acid results in decreased expression of CCN1 mRNA; Zoledronic Acid results in decreased expression of CCN1 protein
CTD PMID:19530242 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO zoledronic acid results in decreased expression of CCNA2 mRNA CTD PMID:24714768 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression
ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNB1 protein
zoledronic acid results in decreased expression of CCNB1 mRNA
CTD PMID:19789217 PMID:20977926 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO zoledronic acid results in decreased expression of CCNB2 mRNA CTD PMID:24714768 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of CCND1 mRNA
zoledronic acid results in decreased expression of CCND1 protein
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCND1 protein
CTD PMID:16621245 PMID:19789217 PMID:24714768 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 multiple interactions
decreases expression
ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCND3 protein
zoledronic acid results in decreased expression of CCND3 protein
CTD PMID:19789217 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNE1 protein CTD PMID:19789217 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccne2 cyclin E2 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of CCNE2 mRNA
zoledronic acid results in increased expression of CCNE2 mRNA
CTD PMID:20977926 PMID:25596134 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Cd14 CD14 molecule increases expression ISO zoledronic acid results in increased expression of CD14 mRNA; zoledronic acid results in increased expression of CD14 protein CTD PMID:24714768 PMID:28871336 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd27 CD27 molecule affects expression ISO zoledronic acid affects the expression of CD27 mRNA CTD PMID:19036117 NCBI chr 4:157,744,881...157,751,609
Ensembl chr 4:157,744,882...157,750,088
JBrowse link
G Cd34 CD34 molecule increases expression ISO zoledronic acid results in increased expression of CD34 mRNA CTD PMID:24714768 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Cd40 CD40 molecule increases expression ISO zoledronic acid results in increased expression of CD40 mRNA CTD PMID:24714768 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO zoledronic acid results in decreased expression of CD40LG mRNA CTD PMID:19036117 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO zoledronic acid results in increased expression of CD44 mRNA CTD PMID:24714768 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO zoledronic acid results in increased expression of CD55 mRNA; zoledronic acid results in increased expression of CD55 protein CTD PMID:20977926 PMID:24714768 PMID:28871336 NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
JBrowse link
G Cd59 CD59 molecule increases expression ISO zoledronic acid results in increased expression of CD59 mRNA CTD PMID:24714768 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cd68 Cd68 molecule increases expression ISO zoledronic acid results in increased expression of CD68 mRNA CTD PMID:24714768 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd69 Cd69 molecule increases expression ISO zoledronic acid results in increased expression of CD69 mRNA CTD PMID:24714768 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd74 CD74 molecule increases expression ISO zoledronic acid results in increased expression of CD74 mRNA CTD PMID:24714768 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cd80 Cd80 molecule increases expression ISO zoledronic acid results in increased expression of CD80 protein CTD PMID:19446661 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd83 CD83 molecule increases expression ISO zoledronic acid results in increased expression of CD83 mRNA CTD PMID:24714768 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cd86 CD86 molecule increases expression ISO zoledronic acid results in increased expression of CD86 protein CTD PMID:19446661 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdc14a cell division cycle 14A increases expression ISO zoledronic acid results in increased expression of CDC14A mRNA CTD PMID:24714768 NCBI chr 2:219,302,577...219,458,345
Ensembl chr 2:219,302,577...219,458,271
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO zoledronic acid results in decreased expression of CDC20 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25c cell division cycle 25C increases expression ISO zoledronic acid results in increased expression of CDC25C mRNA CTD PMID:20977926 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc26 cell division cycle 26 decreases expression ISO zoledronic acid results in decreased expression of CDC26 protein CTD PMID:28871336 NCBI chr 5:78,252,168...78,267,137
Ensembl chr 5:78,253,397...78,267,063
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO zoledronic acid results in increased abundance of [Guanosine Triphosphate binds to CDC42 protein]
zoledronic acid results in increased expression of [CDC42 protein binds to Guanosine Triphosphate]; zoledronic acid results in increased expression of and affects the localization of CDC42 protein
CTD PMID:16734383 PMID:28871336 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdc42ep2 CDC42 effector protein 2 increases expression ISO zoledronic acid results in increased expression of CDC42EP2 mRNA CTD PMID:24714768 NCBI chr 1:221,272,349...221,281,252
Ensembl chr 1:221,272,353...221,281,180
JBrowse link
G Cdc42ep5 CDC42 effector protein 5 increases expression ISO zoledronic acid results in increased expression of CDC42EP5 mRNA CTD PMID:24714768 NCBI chr 1:73,717,207...73,719,600
Ensembl chr 1:73,719,005...73,719,529
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Zoledronic Acid results in decreased expression of CDC45 mRNA CTD PMID:24714768 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdca5 cell division cycle associated 5 increases expression ISO zoledronic acid results in increased expression of CDCA5 protein CTD PMID:28871336 NCBI chr 1:221,448,661...221,462,235
Ensembl chr 1:221,448,661...221,462,233
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO zoledronic acid results in decreased expression of CDCA7 mRNA CTD PMID:24714768 NCBI chr 3:59,153,281...59,163,916
Ensembl chr 3:59,153,280...59,163,913
JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO zoledronic acid results in decreased expression of CDCA8 mRNA CTD PMID:24714768 NCBI chr 5:142,911,310...142,933,536
Ensembl chr 5:142,911,305...142,933,526
JBrowse link
G Cdh4 cadherin 4 increases expression ISO zoledronic acid results in increased expression of CDH4 mRNA CTD PMID:24714768 NCBI chr 3:175,220,520...175,283,144
Ensembl chr 3:175,144,495...175,279,761
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO zoledronic acid results in decreased expression of CDK1 mRNA CTD PMID:24714768 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK2 protein CTD PMID:19789217 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of CDK2AP2 mRNA CTD PMID:16996129 NCBI chr 1:219,345,638...219,347,709
Ensembl chr 1:219,345,918...219,347,728
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK4 protein CTD PMID:19789217 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO CCN1 protein affects the reaction [Zoledronic Acid results in increased expression of CDKN1A protein]
zoledronic acid results in increased expression of CDKN1A protein
CTD PMID:19530242 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Zoledronic Acid co-treated with 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide] results in decreased expression of CDKN1B protein; Gefitinib promotes the reaction [[Zoledronic Acid co-treated with 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide] results in decreased expression of CDKN1B protein]; Zoledronic Acid promotes the reaction [CCN1 protein affects the expression of CDKN1B protein] CTD PMID:16322342 PMID:19530242 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO zoledronic acid results in increased expression of CDKN1C mRNA CTD PMID:20977926 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdkn2aip CDKN2A interacting protein decreases expression ISO zoledronic acid results in decreased expression of CDKN2AIP mRNA CTD PMID:24714768 NCBI chr16:47,664,864...47,670,935
Ensembl chr16:47,665,816...47,669,093
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO zoledronic acid results in increased expression of CDKN2B mRNA CTD PMID:24714768 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO zoledronic acid results in decreased expression of CDKN3 mRNA CTD PMID:24714768 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 decreases expression ISO zoledronic acid results in decreased expression of CDT1 mRNA CTD PMID:24714768 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
JBrowse link
G Cdv3 CDV3 homolog increases expression ISO zoledronic acid results in increased expression of CDV3 mRNA CTD PMID:20977926 NCBI chr 8:111,837,232...111,850,393
Ensembl chr 8:111,839,091...111,850,393
JBrowse link
G Ceacam12 CEA cell adhesion molecule 12 increases expression ISO Zoledronic Acid results in increased expression of CEACAM7 mRNA CTD PMID:24714768 NCBI chr 1:79,474,809...79,481,865
Ensembl chr 1:79,474,809...79,481,865
JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 increases expression ISO zoledronic acid results in increased expression of CEACAM6 mRNA CTD PMID:24714768 NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO zoledronic acid results in increased expression of CEBPA mRNA CTD PMID:20977926 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO zoledronic acid results in increased expression of CEBPB mRNA CTD PMID:24714768 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO zoledronic acid results in increased expression of CEBPD mRNA CTD PMID:24714768 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cenpa centromere protein A decreases expression ISO zoledronic acid results in decreased expression of CENPA mRNA CTD PMID:24714768 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cenpf centromere protein F decreases expression
decreases farnesylation
ISO zoledronic acid results in decreased expression of CENPF mRNA
zoledronic acid results in decreased farnesylation of CENPF protein
CTD PMID:20015195 PMID:24714768 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Cenpi centromere protein I increases expression ISO zoledronic acid results in increased expression of CENPI mRNA CTD PMID:20977926 NCBI chr  X:105,147,045...105,198,798
Ensembl chr  X:105,147,153...105,198,797
JBrowse link
G Cenpm centromere protein M decreases expression ISO zoledronic acid results in decreased expression of CENPM mRNA CTD PMID:24714768 NCBI chr 7:123,464,615...123,476,336
Ensembl chr 7:123,464,490...123,476,238
JBrowse link
G Cep120 centrosomal protein 120 increases expression ISO zoledronic acid results in increased expression of CEP120 mRNA CTD PMID:20977926 NCBI chr18:48,658,495...48,720,570
Ensembl chr18:48,658,495...48,720,472
JBrowse link
G Cep20 centrosomal protein 20 increases expression ISO Zoledronic Acid results in increased expression of CEP20 mRNA CTD PMID:20977926 NCBI chr10:730,215...751,061
Ensembl chr10:730,247...751,061
JBrowse link
G Cep295 centrosomal protein 295 increases expression ISO zoledronic acid results in increased expression of CEP295 mRNA CTD PMID:20977926 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO zoledronic acid results in decreased expression of CEP55 mRNA CTD PMID:24714768 NCBI chr 1:256,745,251...256,760,794
Ensembl chr 1:256,745,288...256,760,796
JBrowse link
G Cep57 centrosomal protein 57 increases expression ISO zoledronic acid results in increased expression of CEP57 mRNA CTD PMID:20977926 NCBI chr 8:12,335,430...12,355,425
Ensembl chr 8:12,335,432...12,355,091
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 increases expression ISO zoledronic acid results in increased expression of CEPT1 mRNA CTD PMID:24714768 NCBI chr 2:209,118,140...209,162,071
Ensembl chr 2:209,118,922...209,160,653
JBrowse link
G Cfb complement factor B increases expression ISO zoledronic acid results in increased expression of CFB mRNA CTD PMID:24714768 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfl1 cofilin 1 increases expression ISO zoledronic acid results in increased expression of CFL1 protein CTD PMID:28871336 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO zoledronic acid results in increased expression of CFLAR mRNA CTD PMID:24714768 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cgn cingulin decreases expression ISO zoledronic acid results in decreased expression of CGN mRNA CTD PMID:24714768 NCBI chr 2:195,909,691...195,937,130
Ensembl chr 2:195,909,626...195,935,878
JBrowse link
G Cgnl1 cingulin-like 1 decreases expression ISO zoledronic acid results in decreased expression of CGNL1 mRNA CTD PMID:24714768 NCBI chr 8:78,126,670...78,278,490
Ensembl chr 8:78,126,675...78,233,430
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO zoledronic acid results in increased expression of CHAC1 mRNA CTD PMID:20977926 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chmp4b charged multivesicular body protein 4B increases expression ISO zoledronic acid results in increased expression of CHMP4B mRNA CTD PMID:20977926 NCBI chr 3:150,188,275...150,227,453
Ensembl chr 3:150,188,455...150,227,405
JBrowse link
G Chmp6 charged multivesicular body protein 6 increases expression ISO zoledronic acid results in increased expression of CHMP6 protein CTD PMID:28871336 NCBI chr10:109,073,678...109,079,348
Ensembl chr10:109,073,678...109,079,348
JBrowse link
G Chst4 carbohydrate sulfotransferase 4 increases expression ISO zoledronic acid results in increased expression of CHST4 mRNA CTD PMID:24714768 NCBI chr19:41,630,060...41,642,373
Ensembl chr19:41,631,715...41,640,367
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression ISO zoledronic acid results in increased expression of CIITA mRNA CTD PMID:24714768 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of CKS2 mRNA CTD PMID:16996129 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Clcn5 chloride voltage-gated channel 5 decreases expression ISO zoledronic acid results in decreased expression of CLCN5 mRNA CTD PMID:24714768 NCBI chr  X:16,170,585...16,196,691
Ensembl chr  X:16,050,780...16,196,789
JBrowse link
G Clcnka chloride voltage-gated channel Ka decreases expression ISO zoledronic acid results in decreased expression of CLCNKA mRNA CTD PMID:24714768 NCBI chr 5:159,931,497...159,946,483
Ensembl chr 5:159,931,511...159,946,446
JBrowse link
G Clcnkb chloride voltage-gated channel Kb decreases expression ISO zoledronic acid results in decreased expression of CLCNKB mRNA CTD PMID:24714768 NCBI chr 5:159,950,384...159,973,576
Ensembl chr 5:159,950,392...159,962,676
JBrowse link
G Cldn14 claudin 14 increases expression ISO zoledronic acid results in increased expression of CLDN14 mRNA CTD PMID:24714768 NCBI chr11:34,132,581...34,142,813
Ensembl chr11:34,132,581...34,142,753
JBrowse link
G Cldn16 claudin 16 decreases expression ISO zoledronic acid results in decreased expression of CLDN16 mRNA CTD PMID:24714768 NCBI chr11:77,683,942...77,703,232
Ensembl chr11:77,681,794...77,703,255
JBrowse link
G Cldn2 claudin 2 decreases expression ISO zoledronic acid results in decreased expression of CLDN2 mRNA CTD PMID:24714768 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Cldn3 claudin 3 increases expression ISO zoledronic acid results in increased expression of CLDN3 mRNA CTD PMID:20977926 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO zoledronic acid results in increased expression of CLEC4E mRNA CTD PMID:24714768 NCBI chr 4:156,271,087...156,276,243
Ensembl chr 4:156,270,920...156,276,304
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin increases expression ISO zoledronic acid results in increased expression of CLN3 mRNA CTD PMID:24714768 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 increases expression ISO zoledronic acid results in increased expression of CNGB1 mRNA CTD PMID:24714768 NCBI chr19:10,142,440...10,206,618
Ensembl chr19:10,142,496...10,206,681
JBrowse link
G Cntnap1 contactin associated protein 1 increases expression ISO zoledronic acid results in increased expression of CNTNAP1 mRNA CTD PMID:24714768 NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614
JBrowse link
G Col16a1 collagen type XVI alpha 1 chain increases expression ISO zoledronic acid results in increased expression of COL16A1 mRNA CTD PMID:24714768 NCBI chr 5:148,257,030...148,311,645
Ensembl chr 5:148,257,642...148,311,645
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression ISO zoledronic acid results in decreased expression of COL18A1 mRNA CTD PMID:24714768 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
increases expression
multiple interactions
ISO zoledronic acid results in decreased expression of COL1A1 mRNA; zoledronic acid results in decreased expression of COL1A1 protein
zoledronic acid results in increased expression of COL1A1 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]
CTD PMID:19597852 PMID:28871336 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression
multiple interactions
ISO zoledronic acid results in increased expression of COL3A1 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]
CTD PMID:28871336 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression
multiple interactions
ISO zoledronic acid results in increased expression of COL4A1 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA]
CTD PMID:28871336 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col4a3 collagen type IV alpha 3 chain decreases expression ISO zoledronic acid results in decreased expression of COL4A3 mRNA CTD PMID:24714768 NCBI chr 9:88,357,528...88,484,735
Ensembl chr 9:88,357,556...88,485,830
JBrowse link
G Col4a5 collagen type IV alpha 5 chain decreases expression ISO zoledronic acid results in decreased expression of COL4A5 mRNA CTD PMID:24714768 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression ISO zoledronic acid results in increased expression of COL5A1 protein CTD PMID:28871336 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col9a2 collagen type IX alpha 2 chain increases expression ISO zoledronic acid results in increased expression of COL9A2 mRNA CTD PMID:24714768 NCBI chr 5:139,962,684...139,979,865
Ensembl chr 5:139,963,002...139,979,864
JBrowse link
G Comp cartilage oligomeric matrix protein increases expression ISO zoledronic acid results in increased expression of COMP protein CTD PMID:28871336 NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO zoledronic acid results in decreased expression of COQ3 mRNA CTD PMID:24714768 NCBI chr 5:36,024,673...36,056,664
Ensembl chr 5:36,024,649...36,056,669
JBrowse link
G Coq4 coenzyme Q4 decreases expression ISO zoledronic acid results in decreased expression of COQ4 mRNA CTD PMID:20977926 NCBI chr 3:8,349,386...8,357,719
Ensembl chr 3:8,349,185...8,357,871
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO zoledronic acid results in decreased expression of COX17 mRNA CTD PMID:20977926 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cp ceruloplasmin increases expression ISO zoledronic acid results in increased expression of CP mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpa4 carboxypeptidase A4 decreases expression ISO zoledronic acid results in decreased expression of CPA4 mRNA CTD PMID:24714768 NCBI chr 4:57,883,849...57,907,826
Ensembl chr 4:57,883,849...57,907,826
JBrowse link
G Cpd carboxypeptidase D increases expression ISO zoledronic acid results in increased expression of CPD mRNA CTD PMID:20977926 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817
JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 decreases expression ISO zoledronic acid results in decreased expression of CPEB2 mRNA CTD PMID:24714768 NCBI chr14:72,327,929...72,382,519
Ensembl chr14:72,331,705...72,380,330
JBrowse link
G Cpne3 copine 3 increases expression ISO zoledronic acid results in increased expression of CPNE3 mRNA CTD PMID:20977926 NCBI chr 5:33,525,307...33,574,610
Ensembl chr 5:33,528,154...33,574,596
JBrowse link
G Cpne8 copine 8 decreases expression ISO zoledronic acid results in decreased expression of CPNE8 mRNA CTD PMID:24714768 NCBI chr 7:131,623,180...131,798,236
Ensembl chr 7:131,623,181...131,798,236
JBrowse link
G Cpq carboxypeptidase Q decreases expression ISO zoledronic acid results in decreased expression of PGCP mRNA CTD PMID:24714768 NCBI chr 7:71,709,174...72,167,413
Ensembl chr 7:71,709,157...72,167,417
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of CPT1A mRNA; zoledronic acid results in decreased expression of CPT1A protein
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA]
CTD PMID:28871336 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of CPT2 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]
CTD PMID:28871336 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Cpvl carboxypeptidase, vitellogenic-like decreases expression ISO zoledronic acid results in decreased expression of CPVL mRNA CTD PMID:24714768 NCBI chr 4:84,026,851...84,137,172
Ensembl chr 4:84,025,926...84,131,030
JBrowse link
G Crat carnitine O-acetyltransferase decreases expression ISO zoledronic acid results in decreased expression of CRAT mRNA CTD PMID:28871336 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Creb5 cAMP responsive element binding protein 5 decreases expression ISO zoledronic acid results in decreased expression of CREB5 mRNA CTD PMID:24714768 NCBI chr 4:83,390,782...83,840,356
Ensembl chr 4:83,391,283...83,836,351
JBrowse link
G Crls1 cardiolipin synthase 1 decreases expression ISO zoledronic acid results in decreased expression of CRLS1 mRNA CTD PMID:20977926 NCBI chr 3:125,503,638...125,522,460
Ensembl chr 3:125,503,638...125,522,441
JBrowse link
G Cryab crystallin, alpha B increases expression ISO zoledronic acid results in increased expression of CRYAB mRNA CTD PMID:24714768 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Csf1 colony stimulating factor 1 increases expression
decreases expression
ISO zoledronic acid results in increased expression of CSF1 mRNA
zoledronic acid results in decreased expression of CSF1 mRNA
CTD PMID:20977926 PMID:24714768 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO zoledronic acid results in increased expression of CSF2 mRNA CTD PMID:24714768 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO zoledronic acid results in decreased expression of CSRP2 mRNA CTD PMID:24714768 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Cst3 cystatin C increases expression ISO zoledronic acid results in increased expression of CST3 protein CTD PMID:28871336 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Ctbs chitobiase increases expression ISO zoledronic acid results in increased expression of CTBS mRNA CTD PMID:20977926 NCBI chr 2:252,305,874...252,320,387
Ensembl chr 2:252,305,874...252,320,387
JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO zoledronic acid results in decreased expression of CTH mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctsb cathepsin B decreases expression ISO zoledronic acid results in decreased expression of CTSB protein CTD PMID:16475674 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsc cathepsin C increases expression ISO zoledronic acid results in increased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctse cathepsin E increases expression ISO zoledronic acid results in increased expression of CTSE mRNA CTD PMID:24714768 NCBI chr13:48,426,833...48,449,493
Ensembl chr13:48,426,820...48,449,490
JBrowse link
G Ctss cathepsin S increases expression ISO zoledronic acid results in increased expression of CTSS mRNA CTD PMID:24714768 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cttn cortactin decreases expression ISO zoledronic acid results in decreased expression of CTTN mRNA CTD PMID:25596134 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 decreases expression ISO zoledronic acid results in decreased expression of CTU2 mRNA CTD PMID:20977926 NCBI chr19:55,300,531...55,305,543
Ensembl chr19:55,300,395...55,305,702
JBrowse link
G Cubn cubilin increases expression ISO zoledronic acid results in increased expression of CUBN mRNA CTD PMID:24714768 NCBI chr17:80,584,921...80,807,181
Ensembl chr17:80,584,878...80,807,243
JBrowse link
G Cul4a cullin 4A increases expression ISO zoledronic acid results in increased expression of CUL4A mRNA CTD PMID:24714768 NCBI chr16:81,718,784...81,756,653
Ensembl chr16:81,719,028...81,756,654
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO zoledronic acid results in increased expression of CX3CL1 mRNA CTD PMID:24714768 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression
ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of CXCL1 mRNA
zoledronic acid results in increased expression of CXCL1 mRNA
CTD PMID:19825521 PMID:24714768 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO zoledronic acid results in increased expression of CXCL10 mRNA CTD PMID:24714768 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO zoledronic acid results in decreased expression of CXCL12 mRNA CTD PMID:24714768 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO zoledronic acid results in decreased expression of CXCL14 mRNA CTD PMID:24714768 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxcl16 C-X-C motif chemokine ligand 16 increases expression ISO zoledronic acid results in increased expression of CXCL16 mRNA CTD PMID:24714768 NCBI chr10:57,060,005...57,064,600
Ensembl chr10:57,060,007...57,064,600
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO zoledronic acid results in increased expression of CXCL2 mRNA CTD PMID:24714768 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of CXCL1 mRNA
zoledronic acid results in increased expression of CXCL1 mRNA
CTD PMID:19825521 PMID:24714768 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO zoledronic acid results in increased expression of CXCR4 mRNA CTD PMID:24714768 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression ISO zoledronic acid results in increased expression of CYB5R3 mRNA CTD PMID:20977926 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 decreases expression ISO zoledronic acid results in decreased expression of CYFIP2 mRNA CTD PMID:24714768 NCBI chr10:31,278,746...31,419,235
Ensembl chr10:31,278,746...31,419,235
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO zoledronic acid results in increased expression of CYP1A1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO zoledronic acid results in increased expression of CYP1A2 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO zoledronic acid results in increased expression of CYP1B1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO zoledronic acid results in increased expression of CYP3A5 mRNA CTD PMID:24714768 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression ISO zoledronic acid results in increased expression of CYP4B1 mRNA CTD PMID:24714768 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO zoledronic acid results in increased expression of CYP51A1 mRNA CTD PMID:24714768 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Cys1 cystin 1 decreases expression ISO zoledronic acid results in decreased expression of CYS1 mRNA CTD PMID:24714768 NCBI chr 6:43,844,937...43,862,131
Ensembl chr 6:43,844,937...43,862,131
JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO zoledronic acid results in increased expression of CYTIP mRNA CTD PMID:24714768 NCBI chr 3:44,150,494...44,225,723
Ensembl chr 3:44,150,992...44,177,689
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression ISO zoledronic acid results in decreased expression of DAPK1 mRNA CTD PMID:19036117 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 increases expression ISO zoledronic acid results in increased expression of DAPP1 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 2:243,175,346...243,224,883
Ensembl chr 2:243,175,346...243,224,883
JBrowse link
G Dcaf15 DDB1 and CUL4 associated factor 15 increases expression ISO zoledronic acid results in increased expression of DCAF15 mRNA CTD PMID:20977926 NCBI chr19:25,212,469...25,219,803
Ensembl chr19:25,212,661...25,220,010
JBrowse link
G Dcdc2 doublecortin domain containing 2 decreases expression ISO zoledronic acid results in decreased expression of DCDC2 mRNA CTD PMID:24714768 NCBI chr17:41,838,201...42,031,265
Ensembl chr17:41,838,201...42,031,265
JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 increases expression ISO zoledronic acid results in increased expression of DCUN1D4 mRNA CTD<