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ONTOLOGY REPORT - ANNOTATIONS
Term:rosuvastatin calcium
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Accession:CHEBI:77249 term browser browse the term
Definition:An organic calcium salt that is the hemicalcium salt of rosuvastatin.
Synonyms:exact_synonym: calcium bis[(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate]
 related_synonym: Crestor;   Formula=C44H54CaF2N6O12S2;   InChI=1S/2C22H28FN3O6S.Ca/c2*1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h2*5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;;+2/p-2/b2*10-9+;/t2*16-,17-;/m11./s1;   InChIKey=LALFOYNTGMUKGG-BGRFNVSISA-L;   Rosuvastatin hemicalcium;   SMILES=[Ca++].CC(C)c1nc(nc(-c2ccc(F)cc2)c1\\C=C\\[C@@H](O)C[C@@H](O)CC([O-])=O)N(C)S(C)(=O)=O.CC(C)c1nc(nc(-c2ccc(F)cc2)c1\\C=C\\[C@@H](O)C[C@@H](O)CC([O-])=O)N(C)S(C)(=O)=O;   ZD 4522
 xref: CAS:147098-20-2 "ChemIDplus";   CAS:147098-20-2 "KEGG DRUG";   DrugBank:DB01098;   HMDB:HMDB0015230;   KEGG:D01915
 xref_mesh: MESH:D000068718
 xref: PMID:20401351 "Europe PMC";   PMID:20448862 "Europe PMC";   PMID:20852754 "Europe PMC";   PMID:21694991 "Europe PMC";   PMID:21963479 "Europe PMC";   PMID:22896825 "Europe PMC";   PMID:22944060 "Europe PMC";   PMID:23019718 "Europe PMC";   PMID:23066186 "Europe PMC";   PMID:23469685 "Europe PMC";   PMID:23574635 "Europe PMC";   PMID:23675248 "Europe PMC";   PMID:23823872 "Europe PMC";   PMID:23999225 "Europe PMC";   PMID:24012665 "Europe PMC";   PMID:24386659 "Europe PMC";   Patent:EP2298745;   Patent:WO2008015563;   Patent:WO2012002741;   Patent:WO2012016479;   Reaxys:7740139 "Reaxys";   Wikipedia:Rosuvastatin

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rosuvastatin calcium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:6480464
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Abcg1 ATP binding cassette subfamily G member 1 JBrowse link 20 9,743,269 9,842,735 RGD:6480464
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:6480464
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Creb5 cAMP responsive element binding protein 5 JBrowse link 4 83,390,782 83,840,356 RGD:6480464
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:6480464
G Cybb cytochrome b-245 beta chain JBrowse link X 14,578,330 14,610,049 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gpr183 G protein-coupled receptor 183 JBrowse link 15 108,364,701 108,376,221 RGD:6480464
G Gzmk granzyme K JBrowse link 2 45,069,136 45,077,154 RGD:6480464
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:6480464
G Il18rap interleukin 18 receptor accessory protein JBrowse link 9 47,225,543 47,255,805 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 JBrowse link 11 35,545,185 35,588,517 RGD:6480464
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:6480464
G Mb myoglobin JBrowse link 7 118,101,633 118,108,864 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Orm1 orosomucoid 1 JBrowse link 5 79,179,668 79,182,820 RGD:6480464
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6480464
G Selp selectin P JBrowse link 13 82,428,914 82,464,629 RGD:6480464
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 4 175,969,549 176,026,227 RGD:6480464
G Slco1b2 solute carrier organic anion transporter family member 1B2 JBrowse link 4 175,814,118 175,881,775 RGD:6480464
G Slco2b1 solute carrier organic anion transporter family, member 2b1 JBrowse link 1 164,623,313 164,671,612 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vnn3 vanin 3 JBrowse link 1 22,649,114 22,661,376 RGD:6480464
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:6480464
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        anti-inflammatory agent 14935
          rosuvastatin calcium 41
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      chalcogen 19322
                        oxygen atom 19283
                          oxygen molecular entity 19283
                            hydroxides 19042
                              oxoacid 18106
                                pnictogen oxoacid 9843
                                  phosphorus oxoacid 8661
                                    phosphoric acids 7332
                                      phosphoric acid 7332
                                        phosphoric acid derivative 6982
                                          phosphate 6982
                                            organic phosphate 6981
                                              phospholipid 288
                                                phosphosphingolipid 75
                                                  ceramide phosphoethanolamine 41
                                                    N-acyl-15-methylhexadecasphinganine-1-phosphoethanolamine 41
                                                      rosuvastatin calcium 41
paths to the root

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