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Accession:CHEBI:77053 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-clostanel. An anthelmintic, it is used (as the dihydrate of the sodium salt) in veterinary medicine for the treatment of fluke and nematode infections.
Synonyms:exact_synonym: rac-N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide
 related_synonym: 5'-chloro-alpha(4)-(p-chlorophenyl)-alpha(4)-cyano-3,5-diiodo-2',4'-salicyloxylidide;   Flukiver;   R 31,520;   R 31520;   Seponver;   closantelum
 xref: CAS:57808-65-8 "ChemIDplus";   CAS:57808-65-8 "KEGG DRUG";   KEGG:D03567
 xref_mesh: MESH:C023342
 xref: PMID:21247019 "Europe PMC";   PMID:22916226 "Europe PMC";   PMID:23992251 "Europe PMC";   PMID:3330516 "Europe PMC";   PMID:4054009 "Europe PMC";   PMID:7119989 "Europe PMC";   PMID:7571353 "Europe PMC";   PMID:9138034 "Europe PMC";   Patent:BE839481;   Patent:US4005218;   Reaxys:6249214 "Reaxys"

show annotations for term's descendants       view all columns           Sort by:
closantel term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:6480464
G Slc25a31 solute carrier family 25 member 31 JBrowse link 2 127,538,323 127,554,276 RGD:6480464
G Slc25a4 solute carrier family 25 member 4 JBrowse link 16 49,266,903 49,270,698 RGD:6480464
G Slc25a5 solute carrier family 25 member 5 JBrowse link X 123,404,570 123,407,637 RGD:6480464
G Slc25a6 solute carrier family 25 member 6 JBrowse link 18 70,959,872 70,961,040 RGD:6480464
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:6480464
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      chemical substance 10725
        mixture 9929
          racemate 8658
            closantel 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                monocarboxylic acid amide 13180
                                                  N-\{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl\}-2-hydroxy-3,5-diiodobenzamide 8
                                                    (R)-closantel 8
                                                      closantel 8
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.