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G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
decreases activity |
ISO |
Bromhexine results in decreased activity of KCNH2 protein |
CTD |
PMID:28551711 |
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NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
Bromhexine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
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NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
A1bg |
alpha-1-B glycoprotein |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of A1BG mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of A1BG mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased methylation of ABCA1 promoter] |
CTD |
PMID:31150806 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abca5 |
ATP binding cassette subfamily A member 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA5 mRNA] |
CTD |
PMID:31004932 |
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NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO EXP |
Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]; Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] |
CTD |
PMID:10636889 PMID:18474546 PMID:22914566 PMID:23867903 PMID:25824409 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC1 mRNA]; Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC1 protein]; Acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]; Buthionine Sulfoximine analog inhibits the reaction [Acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]] |
CTD |
PMID:11820781 PMID:15473893 PMID:22914566 PMID:23867903 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA] Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCC2 protein] |
CTD |
PMID:22914566 PMID:23867903 PMID:34303734 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC3 protein] |
CTD |
PMID:11820781 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of ABCG1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Abcg4 |
ATP binding cassette subfamily G member 4 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ABCG4 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCG4 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881
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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [NSC 680410 results in decreased phosphorylation of ABL1 protein] |
CTD |
PMID:16481037 |
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NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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G |
Ache |
acetylcholinesterase |
multiple interactions affects response to substance |
EXP ISO |
[Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Cadmium results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Dimethoate results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of ACHE protein] ACHE protein affects the susceptibility to Acetylcysteine Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of ACHE mRNA alternative form]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein] |
CTD |
PMID:20399762 PMID:20688495 PMID:26769589 PMID:27087133 PMID:27163631 PMID:28499986 PMID:29253600 PMID:30639957 PMID:31173782 PMID:34425170 More...
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Acp3 |
acid phosphatase 3 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACP3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
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G |
Acsm5 |
acyl-CoA synthetase medium-chain family member 5 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACSM5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACSM5 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588
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G |
Acss1 |
acyl-CoA synthetase short-chain family member 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACSS1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ACTA2 mRNA] Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ACTA2 protein] |
CTD |
PMID:16757516 PMID:21134390 PMID:32659284 PMID:33131013 PMID:35622622 PMID:36493885 More...
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Adam33 |
ADAM metallopeptidase domain 33 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ADAM33 mRNA] |
CTD |
PMID:29753051 |
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NCBI chr 3:118,262,395...118,283,456
Ensembl chr 3:118,271,029...118,283,461
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G |
Adgrb2 |
adhesion G protein-coupled receptor B2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540
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G |
Adgrb3 |
adhesion G protein-coupled receptor B3 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855
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G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Ethanol results in increased expression of ADH1 mRNA] |
CTD |
PMID:20705415 |
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NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Palmitates results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in decreased expression of ADIPOQ protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]] |
CTD |
PMID:17471172 PMID:21912612 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adipor2 |
adiponectin receptor 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] |
CTD |
PMID:21912612 |
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NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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G |
Agt |
angiotensinogen |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] Acetylcysteine inhibits the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species] |
CTD |
PMID:15849355 PMID:30703374 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Agtr1a |
angiotensin II receptor, type 1a |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of AGTR1 mRNA] |
CTD |
PMID:23603059 |
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NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Ahr |
aryl hydrocarbon receptor |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of AHR protein Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of and affects the localization of AHR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of AHR protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1A enhancer]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1B enhancer] |
CTD |
PMID:18022818 PMID:21569840 PMID:31551408 PMID:35123993 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride affects the localization of AIFM1 protein] Acetylcysteine inhibits the reaction [bisphenol A affects the localization of AIFM1 protein] Acetylcysteine inhibits the reaction [1,12-benzoperylene results in increased expression of AIFM1 protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone affects the localization of AIFM1 protein] |
CTD |
PMID:18034189 PMID:18412143 PMID:18506790 PMID:18951928 PMID:19679660 PMID:21741372 PMID:27189055 PMID:31518672 More...
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Aimp1 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of AIMP1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
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G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AKR1C3 mRNA] |
CTD |
PMID:18829485 PMID:21787718 |
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NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased activity of and results in increased phosphorylation of AKT1 protein]; [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of and affects the localization of AKT1 protein]; Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [butein results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E affects the phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cyadox results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Daunorubicin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [divinyl sulfone analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Morpholines analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [morusin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [N-arachidonoylalanine results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [oenothein B results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Oligopeptides analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Patulin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [synaptamide results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [tubocapsenolide A results in increased degradation of AKT1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of AKT1 protein]; Acetylcysteine results in increased activity of and results in increased phosphorylation of AKT1 protein Acetylcysteine inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of AKT1 mRNA] Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Zinc results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:12168106 PMID:12614848 PMID:16137721 PMID:16731823 PMID:18442981 PMID:21055460 PMID:21195169 PMID:21787718 PMID:22427991 PMID:22867088 PMID:23000059 PMID:23159718 PMID:23948867 PMID:24299490 PMID:24449419 PMID:24489685 PMID:24582688 PMID:24875536 PMID:24933620 PMID:25199686 PMID:25471227 PMID:25939952 PMID:25944616 PMID:26514923 PMID:26804764 PMID:26942697 PMID:27106530 PMID:27117918 PMID:27411387 PMID:27658547 PMID:28087840 PMID:28600122 PMID:29604266 PMID:30265530 PMID:30452899 PMID:30797898 PMID:30871965 PMID:31068539 PMID:31157476 PMID:32305283 PMID:32745510 PMID:33035517 PMID:34963561 PMID:35130734 PMID:36810933 More...
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alad |
aminolevulinate dehydratase |
multiple interactions |
EXP |
Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [sodium arsenite results in decreased activity of ALAD protein]] |
CTD |
PMID:16959597 |
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NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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G |
Alb |
albumin |
multiple interactions affects binding |
EXP |
Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Acetylcysteine inhibits the reaction [ALB protein modified form results in decreased expression of MFN2 protein]; Acetylcysteine inhibits the reaction [ALB protein modified form results in increased abundance of Hydrogen Peroxide]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]; Acetylcysteine inhibits the reaction [Mustard Gas results in increased expression of ALB protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]] N-acetyl-L-cysteine binds Alb protein in serum |
CTD RGD |
PMID:11428623 PMID:20804811 PMID:24485406 PMID:27997345 PMID:12458670 |
RGD:1625447 |
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Nitroglycerin results in decreased activity of ALDH2 protein] |
CTD |
PMID:17585900 |
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NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Alk |
ALK receptor tyrosine kinase |
multiple interactions |
ISO |
Acetylcysteine affects the phosphorylation of and affects the activity of ALK protein mutant form |
CTD |
PMID:19503098 |
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NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
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G |
Alkbh5 |
alkB homolog 5, RNA demethylase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ALKBH5 mRNA] Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of ALKBH5 mRNA] |
CTD |
PMID:31004932 PMID:34425375 |
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NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of ALPL mRNA] |
CTD |
PMID:34547296 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Amacr |
alpha-methylacyl-CoA racemase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AMACR mRNA] |
CTD |
PMID:18829485 |
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NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
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G |
Ang |
angiogenin |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of ANG protein] |
CTD |
PMID:26138014 |
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NCBI chr15:24,312,711...24,323,361
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G |
Angpt1 |
angiopoietin 1 |
decreases secretion |
ISO |
Acetylcysteine results in decreased secretion of ANGPT1 protein |
CTD |
PMID:19622383 |
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NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ANGPTL4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Ankrd29 |
ankyrin repeat domain 29 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ANKRD29 mRNA |
CTD |
PMID:22129741 |
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NCBI chr18:3,436,301...3,494,292
Ensembl chr18:3,436,303...3,494,296
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G |
Anxa5 |
annexin A5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ANXA5 protein]; Acetylcysteine inhibits the reaction [Tin Fluorides results in increased expression of ANXA5 protein] |
CTD |
PMID:22093110 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Aoc1 |
amine oxidase, copper containing 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Methotrexate results in increased activity of AOC1 protein] |
CTD |
PMID:20885979 |
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NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of APAF1 mRNA]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of APAF1 protein] Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of APAF1 protein] |
CTD |
PMID:15877105 PMID:19477266 PMID:35396826 |
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NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of APEX1 protein] Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of APEX1 mRNA] |
CTD |
PMID:12231548 PMID:17938202 |
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NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
multiple interactions decreases expression |
EXP |
Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of APEX2 mRNA] Acetylcysteine results in decreased expression of APEX2 mRNA |
CTD |
PMID:26332274 |
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NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439
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G |
Aph1b |
aph-1 homolog B, gamma secretase subunit |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of APH1B mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
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G |
Apoe |
apolipoprotein E |
increases expression multiple interactions |
EXP |
Acetylcysteine results in increased expression of APOE mRNA Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of APOE mRNA] |
CTD |
PMID:33188856 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [APP protein affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of NLRP3 protein] |
CTD |
PMID:12684028 PMID:28004443 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp2 |
aquaporin 2 |
increases expression |
EXP |
Acetylcysteine results in increased expression of AQP2 protein |
CTD |
PMID:23183129 |
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NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the activity of AR protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR mRNA]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR protein] |
CTD |
PMID:16928829 PMID:18829485 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Arl13a |
ADP ribosylation factor like GTPase 13A |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ARL13A mRNA |
CTD |
PMID:22129741 |
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NCBI chr X:97,380,370...97,406,704
Ensembl chr X:97,380,390...97,406,702
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Curcumin results in increased degradation of ARNT protein] |
CTD |
PMID:16880289 |
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NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Arrdc3 |
arrestin domain containing 3 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ARRDC3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
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G |
Art4 |
ADP-ribosyltransferase 4 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of ART4 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ASNS mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Astl |
astacin like metalloendopeptidase |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ASTL mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868
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G |
Atf2 |
activating transcription factor 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of ATF2 protein] Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of ATF2 protein] |
CTD |
PMID:19654923 PMID:22288910 |
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NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of and affects the localization of ATF3 protein] |
CTD |
PMID:25531190 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions decreases expression increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased expression of ATF4 protein] [Acetylcysteine co-treated with Trichloroethylene] results in increased expression of ATF4 mRNA; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ATF4 protein] Acetylcysteine results in decreased expression of ATF4 protein Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ATF4 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ATF4 protein]; Acetylcysteine promotes the reaction [perfluorooctanoic acid results in increased expression of ATF4 mRNA] Acetylcysteine results in increased expression of ATF4 protein |
CTD |
PMID:15788408 PMID:19722195 PMID:21266191 PMID:24291486 PMID:25451595 PMID:25568320 PMID:27484784 PMID:27634458 PMID:27816613 PMID:28754437 PMID:31330229 PMID:32506763 PMID:32578922 PMID:36396003 PMID:37072049 More...
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Sodium Selenite results in increased expression of ATF6 protein]; Acetylcysteine results in increased metabolism of and results in increased activity of ATF6 protein Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF6 protein modified form]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ATF6 protein] Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of ATF6 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased cleavage of ATF6 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ATF6 protein] |
CTD |
PMID:18077580 PMID:19722195 PMID:21198628 PMID:21911445 PMID:24291486 PMID:25451595 PMID:31330229 PMID:34520753 More...
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg10 |
autophagy related 10 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG10 mRNA] |
CTD |
PMID:24614525 |
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NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
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G |
Atg12 |
autophagy related 12 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG12 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [Vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]] Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG12 mRNA] |
CTD |
PMID:20543569 PMID:24614525 PMID:29307831 PMID:30205151 PMID:33146789 PMID:34439521 More...
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NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
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G |
Atg14 |
autophagy related 14 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATG14 mRNA] |
CTD |
PMID:34439521 |
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NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
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G |
Atg16l1 |
autophagy related 16-like 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG16L1 protein] |
CTD |
PMID:30205151 |
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NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
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G |
Atg16l2 |
autophagy related 16-like 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG16L2 mRNA] |
CTD |
PMID:33146789 |
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NCBI chr 1:155,687,386...155,703,419
Ensembl chr 1:155,684,564...155,703,420
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G |
Atg4a |
autophagy related 4A, cysteine peptidase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ATG4A protein] |
CTD |
PMID:29179951 |
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NCBI chr X:104,665,345...104,765,271
Ensembl chr X:104,665,345...104,765,268
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G |
Atg4c |
autophagy related 4C, cysteine peptidase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of ATG4C mRNA] |
CTD |
PMID:34425375 |
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NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of ATG5 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG5 mRNA] |
CTD |
PMID:20543569 PMID:24614525 PMID:28600122 PMID:29307831 PMID:30205151 PMID:33146789 PMID:33462182 More...
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NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATG7 mRNA]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG7 protein]; Acetylcysteine inhibits the reaction [Apigenin results in increased expression of ATG7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG7 mRNA] |
CTD |
PMID:29247770 PMID:29307831 PMID:30205151 PMID:31319114 PMID:33462182 |
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NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
Atm |
ATM serine/threonine kinase |
multiple interactions increases phosphorylation |
ISO EXP |
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ATM protein]; Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of ATM protein modified form]; Acetylcysteine inhibits the reaction [ATM protein promotes the reaction [Doxorubicin results in increased activity of TP53 protein]]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK1 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of NBN protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of SMC1A protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [polyhexamethyleneguanidine results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased phosphorylation of ATM protein] Acetylcysteine affects the reaction [yttrium chloride affects the expression of ATM protein] Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of ATM protein] Acetylcysteine results in increased phosphorylation of ATM protein |
CTD |
PMID:15489221 PMID:23274516 PMID:24792323 PMID:26451628 PMID:31168028 PMID:31715134 PMID:32142722 PMID:35088107 More...
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atox1 |
antioxidant 1 copper chaperone |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATOX1 mRNA] |
CTD |
PMID:36315628 |
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NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of ATP1A1 protein] |
CTD |
PMID:10506578 |
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NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
increases expression multiple interactions |
ISO EXP |
Acetylcysteine results in increased expression of ATP2A2 mRNA Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of ATP2A2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP2A2 protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATP2A2 mRNA] |
CTD |
PMID:10625299 PMID:16084531 PMID:17005195 PMID:36315628 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Atp5f1a |
ATP synthase F1 subunit alpha |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of ATP5F1A mRNA] |
CTD |
PMID:36493885 |
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NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
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G |
Atp6v0d1 |
ATPase H+ transporting V0 subunit D1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATP6V0D1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATP6V0D1 mRNA] |
CTD |
PMID:29307831 PMID:31319114 |
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NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450
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G |
Atp6v0d2 |
ATPase H+ transporting V0 subunit D2 |
multiple interactions |
EXP ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ATP6V0D2 mRNA [Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of ATP6V0D2 mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA] |
CTD |
PMID:22129741 PMID:30742845 |
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NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
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G |
Atr |
ATR serine/threonine kinase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ATR protein] |
CTD |
PMID:26451628 |
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NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
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G |
Atxn1 |
ataxin 1 |
affects localization multiple interactions |
ISO |
Acetylcysteine affects the localization of ATXN1 protein mutant form Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of ATXN1 protein mutant form]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ATXN1 protein mutant form] |
CTD |
PMID:12893416 |
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NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
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G |
Aurkb |
aurora kinase B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of AURKB protein] |
CTD |
PMID:28343997 |
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NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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G |
B2m |
beta-2 microglobulin |
decreases response to substance multiple interactions |
ISO |
Acetylcysteine results in decreased susceptibility to B2M protein modified form Acetylcysteine inhibits the reaction [B2M protein modified form results in increased abundance of Reactive Oxygen Species] |
CTD |
PMID:21864514 |
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NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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G |
B3galt5 |
Beta-1,3-galactosyltransferase 5 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of B3GALT5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:35,584,273...35,630,922
Ensembl chr11:35,585,220...35,630,917
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G |
B3gnt9 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of B3GNT9 mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:33,129,740...33,134,048
Ensembl chr19:33,128,142...33,132,344
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G |
Bach1 |
BTB domain and CNC homolog 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenic trioxide affects the localization of BACH1 protein] |
CTD |
PMID:19350554 |
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NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [cordycepin results in increased expression of BAD protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BAD protein] Acetylcysteine results in increased expression of BAD mRNA |
CTD |
PMID:21310227 PMID:22245127 PMID:26332274 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag3 |
BAG cochaperone 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of BAG3 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 protein] Acetylcysteine inhibits the reaction [Cadmium results in increased expression of BAK1] Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of BAK1 mRNA] |
CTD |
PMID:21533816 PMID:21549813 PMID:22085843 PMID:23339468 PMID:28296042 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Barx2 |
BARX homeobox 2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BARX2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased activity of BAX protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased expression of BAX protein]] Acetylcysteine results in increased expression of BAX protein 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Buthionine Sulfoximine] results in decreased expression of BAX protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased localization of BAX protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BAX protein]; Acetylcysteine inhibits the reaction [chromium tripicolinate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of and results in increased activity of BAX protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenbendazole analog results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenbendazole results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [gingerol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [glabridin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [perfosfamide affects the folding of BAX protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of BAX]; Acetylcysteine inhibits the reaction [Propofol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of BAX protein]]; Acetylcysteine inhibits the reaction [surfactin peptide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester) affects the expression of BAX protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased expression of BAX protein] Acetylcysteine results in decreased expression of BAX protein Acetylcysteine results in increased expression of BAX mRNA Acetylcysteine affects the reaction [lead acetate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [4-nonylphenol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of BAX mRNA] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases expression of BAX protein in the stomach) |
CTD RGD |
PMID:11166918 PMID:11341981 PMID:15496615 PMID:15735709 PMID:16169029 PMID:17237268 PMID:17542780 PMID:17574045 PMID:18034189 PMID:18412143 PMID:18547707 PMID:19376147 PMID:19954742 PMID:20674558 PMID:20981856 PMID:21310227 PMID:21533816 PMID:21549813 PMID:21616140 PMID:22085843 PMID:22245127 PMID:22704995 PMID:23711929 PMID:24036456 PMID:25034532 PMID:25845326 PMID:26332274 PMID:26512966 PMID:26772155 PMID:26797587 PMID:26804764 PMID:27189055 PMID:27816613 PMID:28804952 PMID:29087013 PMID:29248572 PMID:29945211 PMID:30104959 PMID:30769050 PMID:30797898 PMID:30917517 PMID:31173782 PMID:31313457 PMID:31368586 PMID:32402895 PMID:32527420 PMID:32540572 PMID:33031904 PMID:33485121 PMID:33971260 PMID:34547296 PMID:35430258 PMID:35569513 PMID:36029289 PMID:36070022 PMID:29408335 More...
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RGD:127284846 |
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA] Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of BBC3 protein] |
CTD |
PMID:24291486 PMID:32540572 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcas1 |
brain enriched myelin associated protein 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BCAS1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:159,136,077...159,219,072
Ensembl chr 3:159,136,083...159,219,106
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G |
Bche |
butyrylcholinesterase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein] Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of BCHE protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of BCHE protein] |
CTD |
PMID:27087133 PMID:34425170 |
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NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression decreases response to substance multiple interactions |
ISO EXP |
Acetylcysteine results in decreased expression of BCL2 protein BCL2 results in decreased susceptibility to Acetylcysteine Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of BCL2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in decreased expression of BCL2 protein]] 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Buthionine Sulfoximine] results in increased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in decreased expression of BCL2 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; Acetylcysteine inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [glabridin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Propofol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [salvin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [surfactin peptide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester) affects the expression of BCL2 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of BCL2 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of BCL2 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in decreased expression of BCL2 protein] Acetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of BCL2 protein] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases expression of BCL2 protein in the stomach) |
CTD RGD |
PMID:11341981 PMID:17041759 PMID:17395010 PMID:17542780 PMID:18077580 PMID:18412143 PMID:19082730 PMID:19679660 PMID:19954742 PMID:20674558 PMID:21310227 PMID:21549813 PMID:21600978 PMID:21616140 PMID:22085843 PMID:22245127 PMID:22578287 PMID:22704995 PMID:22976841 PMID:23711929 PMID:24036456 PMID:24909818 PMID:25034532 PMID:25845326 PMID:26079211 PMID:26772155 PMID:27816613 PMID:28804952 PMID:28918123 PMID:29248572 PMID:30104959 PMID:30769050 PMID:30796935 PMID:30797898 PMID:30917517 PMID:31157476 PMID:31173782 PMID:31368586 PMID:31563593 PMID:31900833 PMID:32402895 PMID:32527420 PMID:33002460 PMID:33485121 PMID:34547296 PMID:34599545 PMID:36029289 PMID:29408335 More...
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RGD:127284846 |
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [Carboplatin results in decreased expression of BCL2L1 protein] Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of BCL2L1 protein] |
CTD |
PMID:18281123 PMID:18483861 PMID:20594983 PMID:21310227 PMID:22085843 PMID:22245127 PMID:23711929 PMID:30917517 PMID:31313457 PMID:31900833 More...
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased expression of BCL2L11 protein] |
CTD |
PMID:15173094 |
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NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Bcl6 |
BCL6, transcription repressor |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BCL6 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
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G |
Bdkrb1 |
bradykinin receptor B1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA] |
CTD |
PMID:22264228 |
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NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of BDNF protein] |
CTD |
PMID:16553631 PMID:26138014 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [brazilin results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of and results in increased phosphorylation of BECN1 protein]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [pyrovalerone analog results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Vorinostat results in increased expression of BECN1 protein] Acetylcysteine inhibits the reaction [4-nonylphenol results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of BECN1 protein] Acetylcysteine inhibits the reaction [[CASP2 protein affects the susceptibility to Rotenone] which results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Trichloroethylene results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of BECN1 protein] |
CTD |
PMID:20543569 PMID:21216964 PMID:24614525 PMID:26588882 PMID:26804764 PMID:27106530 PMID:28025121 PMID:28063998 PMID:28578026 PMID:28600122 PMID:29923297 PMID:31563593 PMID:32687844 PMID:33146789 PMID:34439521 PMID:36849104 More...
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BGLAP mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BGLAP protein] |
CTD |
PMID:34547296 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO EXP |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [sanguinarine results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein] Acetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein] |
CTD |
PMID:16169029 PMID:17574045 PMID:21310227 PMID:23660334 PMID:23711929 PMID:25034532 PMID:25845326 PMID:30408460 More...
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bik |
BCL2-interacting killer |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of BIK protein] |
CTD |
PMID:31313457 |
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NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC2 protein] |
CTD |
PMID:19679660 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC3 protein] |
CTD |
PMID:19679660 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BIRC5 protein] |
CTD |
PMID:21741372 PMID:23711929 PMID:25034532 PMID:31837377 PMID:34599545 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BMAL1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bmp5 |
bone morphogenetic protein 5 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BMP5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
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G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions |
EXP |
[Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of BMP7 mRNA |
CTD |
PMID:21051528 |
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NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Bnip3 |
BCL2 interacting protein 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein] |
CTD |
PMID:19442826 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Bpgm |
bisphosphoglycerate mutase |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of BPGM mRNA |
CTD |
PMID:16084531 |
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NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
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G |
Btg1 |
BTG anti-proliferation factor 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of BTG1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
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G |
C3 |
complement C3 |
multiple interactions |
EXP |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of C3 protein modified form]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C3 protein] |
CTD |
PMID:20946910 PMID:32924446 |
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NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
C5 |
complement C5 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C5 protein] |
CTD |
PMID:32924446 |
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NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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G |
Cacna1g |
calcium voltage-gated channel subunit alpha1 G |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CACNA1G mRNA |
CTD |
PMID:22129741 |
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NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
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G |
Capn1 |
calpain 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of CAPN1 protein] |
CTD |
PMID:25451595 |
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NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
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G |
Capn2 |
calpain 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of CAPN2 protein] |
CTD |
PMID:25451595 |
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NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO EXP |
[Acetylcysteine co-treated with Cobalt] results in decreased expression of CASP1 protein; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of CASP1 mRNA]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [Cobalt results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [Ethanol results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of and results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [TNF protein results in increased cleavage of and results in increased activity of CASP1 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]] Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of CASP1 mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide inhibits the reaction [anthrax toxin results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [Glucose results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein] Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of CASP1 protein] |
CTD |
PMID:23940760 PMID:24337744 PMID:24885895 PMID:25929180 PMID:26079697 PMID:26086368 PMID:26435000 PMID:26809137 PMID:26901245 PMID:27783111 PMID:28004443 PMID:28814068 PMID:30205151 PMID:30878009 PMID:30977640 PMID:32805375 PMID:34217685 PMID:34238121 PMID:34510229 PMID:34791735 PMID:35190838 PMID:36055550 PMID:36347317 PMID:36354081 More...
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of and results in increased activity of CASP12 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of CASP12 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP12 protein]] Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP12 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP12 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] |
CTD |
PMID:18077580 PMID:21145380 PMID:21616140 PMID:25451595 PMID:28296042 PMID:31330229 More...
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp14 |
caspase 14 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CASP14 protein] |
CTD |
PMID:16137721 |
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NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
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G |
Casp2 |
caspase 2 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP2 protein] Acetylcysteine inhibits the reaction [[CASP2 protein affects the susceptibility to Rotenone] which results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased cleavage of CASP2 protein] |
CTD |
PMID:15158148 PMID:17041759 PMID:21216964 PMID:30408460 |
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NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions increases activity decreases activity increases expression |
ISO EXP |
Acetylcysteine results in increased cleavage of CASP3 protein [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Acetylcysteine affects the reaction [nonylphenol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [mancozeb results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [nitrofen results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [POMC protein promotes the reaction [cobaltous chloride results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Acetylcysteine results in increased expression of CASP3 protein modified form] Acetylcysteine results in increased activity of CASP3 Acetylcysteine results in decreased activity of CASP3 protein [Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Naphthalimides co-treated with Spermidine] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [[Pentachlorophenol co-treated with copper-1,10-phenanthroline] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Vitamin K 2 co-treated with Arsenic Trioxide] results in increased expression of CASP3]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [aristolochic acid I results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [butein results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [chelerythrine results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [chromium tripicolinate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [crocin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [dimethoxycurcumin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Eosine I Bluish results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [fenpyroximate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [glabridin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [manumycin results in increased activity of CASP3]; Acetylcysteine inhibits the reaction [menadione epoxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [osimertinib results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [platycodin D results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Prodigiosin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Propofol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [pyrovalerone analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Reactive Oxygen Species results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [surfactin peptide results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased cleavage of CASP3 protein]; Acetylcysteine promotes the reaction [brazilin results in increased activity of CASP3 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP3 protein]; Acetylcysteine promotes the reaction [sinularin results in increased cleavage of CASP3 protein]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased cleavage of CASP3 protein]; Oxygen deficiency affects the reaction [Acetylcysteine results in increased activity of CASP3 protein] [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [4-nonylphenol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [arsenite results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Diquat results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Estradiol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP3]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [JP8 aviation fuel results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Lead results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [menadione epoxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Pilocarpine results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Propranolol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of CASP3 protein modified form] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP3 protein in the stomach) N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases cleavage of CASP3 protein in stomach] |
CTD RGD |
PMID:11969376 PMID:12168106 PMID:12750841 PMID:12754411 PMID:14660655 PMID:15050407 PMID:15158148 PMID:15375156 PMID:15496615 PMID:15545282 PMID:15582350 PMID:15683462 PMID:15816534 PMID:16014620 PMID:16169029 PMID:16282376 PMID:17041759 PMID:17136323 PMID:17309078 PMID:17332930 PMID:17468103 PMID:17542780 PMID:17574045 PMID:17888894 PMID:18077580 PMID:18281123 PMID:18483861 PMID:18547707 PMID:18703135 PMID:18791325 PMID:18804340 PMID:19014919 PMID:19082730 PMID:19376147 PMID:19409983 PMID:19477266 PMID:19523979 PMID:19536524 PMID:19722195 PMID:19771260 PMID:19837105 PMID:19840221 PMID:20100472 PMID:20114059 PMID:20362650 PMID:20594983 PMID:20632440 PMID:20674558 PMID:20883752 PMID:20946910 PMID:20981856 PMID:21145380 PMID:21166495 PMID:21221209 PMID:21242791 PMID:21300145 PMID:21310227 PMID:21349322 PMID:21418039 PMID:21453688 PMID:21533816 PMID:21549813 PMID:21565247 PMID:21600974 PMID:21616140 PMID:21741372 PMID:21804221 PMID:21843585 PMID:21998720 PMID:22002103 PMID:22085843 PMID:22260869 PMID:22440610 PMID:22578287 PMID:22710416 PMID:22714038 PMID:22824136 PMID:22909951 PMID:22922937 PMID:23088786 PMID:23405080 PMID:23677851 PMID:23711929 PMID:23836369 PMID:23867903 PMID:24036456 PMID:24157283 PMID:24273890 PMID:24291486 PMID:24299490 PMID:24412703 PMID:24614525 PMID:24634002 PMID:24908156 PMID:24998639 PMID:25034532 PMID:25341683 PMID:25568320 PMID:25845326 PMID:25891866 PMID:25940438 PMID:25947082 PMID:26079211 PMID:26124276 PMID:26282491 PMID:26549478 PMID:26588882 PMID:26630137 PMID:26772155 PMID:26804764 PMID:27106530 PMID:27417252 PMID:27484784 PMID:27539140 PMID:28025121 PMID:28063998 PMID:28219700 PMID:28237877 PMID:28296042 PMID:28548367 PMID:28578026 PMID:28778520 PMID:28804952 PMID:28918123 PMID:29087013 PMID:29108775 PMID:29111403 PMID:29248572 PMID:29432840 PMID:29454061 PMID:29484840 PMID:29774349 PMID:29944906 PMID:29945211 PMID:30037311 PMID:30236763 PMID:30240709 PMID:30259999 PMID:30590774 PMID:30633982 PMID:30641872 PMID:30769050 PMID:30796935 PMID:30871965 PMID:30917517 PMID:31077745 PMID:31157476 PMID:31173782 PMID:31229567 PMID:31313457 PMID:31330229 PMID:31381934 PMID:31408635 PMID:31433961 PMID:32506763 PMID:32540572 PMID:32662599 PMID:32708634 PMID:32924446 PMID:33031904 PMID:33485121 PMID:33592258 PMID:33961949 PMID:34547296 PMID:34627931 PMID:34816377 PMID:34850538 PMID:34897981 PMID:35085590 PMID:35123993 PMID:35130734 PMID:35396826 PMID:35430258 PMID:35622622 PMID:35738838 PMID:35810264 PMID:36029289 PMID:36070022 PMID:36252918 PMID:36493885 PMID:36933581 PMID:29408335 PMID:32106377 More...
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RGD:127284846, RGD:127284886 |
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CASP4 mRNA] Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP4 protein] Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP4 mRNA] |
CTD |
PMID:16137721 PMID:19477266 PMID:22922937 PMID:25341683 |
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NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp6 |
caspase 6 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein] Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP6 protein] Acetylcysteine inhibits the reaction [surfactin peptide results in increased cleavage of and results in increased activity of CASP6 protein] |
CTD |
PMID:15158148 PMID:19954742 PMID:24157283 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp7 |
caspase 7 |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP7 mRNA] Acetylcysteine results in decreased expression of CASP7 protein modified form Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP7 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein] Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP7 protein] |
CTD |
PMID:17136323 PMID:19771260 PMID:20594983 PMID:21145380 PMID:21549813 PMID:21843585 PMID:22085843 PMID:22260869 PMID:22909951 PMID:23405080 PMID:24157283 PMID:24998639 PMID:25824409 PMID:27106530 PMID:27539140 PMID:28087840 PMID:28161410 PMID:29800641 PMID:30408460 PMID:30917517 PMID:31313457 PMID:31330229 PMID:31433961 PMID:34627931 PMID:36252918 More...
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NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO EXP |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of CASP8 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of CASP8 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of CASP8 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of CASP8 protein]]; Acetylcysteine inhibits the reaction [cannabidiol hydroxyquinone results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP8 protein] N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP8 protein in the stomach) [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein]; [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of CASP8 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP8 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of CASP8 protein] Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP8 mRNA]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [sinularin results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP8 protein]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased activity of and results in increased cleavage of CASP8 protein] |
CTD RGD |
PMID:16169029 PMID:17574045 PMID:18791325 PMID:19014919 PMID:19477266 PMID:20184945 PMID:20576514 PMID:20674558 PMID:20883752 PMID:20946910 PMID:21310227 PMID:22578287 PMID:23711929 PMID:23867903 PMID:24614525 PMID:25034532 PMID:25845326 PMID:27313093 PMID:27484784 PMID:28087840 PMID:28219700 PMID:28548367 PMID:28918123 PMID:29432840 PMID:30917517 PMID:32506763 PMID:32662599 PMID:35833596 PMID:29408335 More...
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RGD:127284846 |
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [monomethylarsonous acid results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP9 protein]]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP9 protein] [Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP9 protein; Acetylcysteine affects the reaction [SOD2 protein affects the activity of CASP9 protein]; Acetylcysteine inhibits the reaction [10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [ganoderic acid analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [oenothein B results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Propofol results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [sinularin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Soot analog results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP9 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP9 protein] Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [CASP9 protein binds to CYCS protein]]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP9]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein] Acetylcysteine results in increased expression of CASP9 protein modified form N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP9 protein in the stomach) N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases cleavage of CASP9 protein in stomach] |
CTD RGD |
PMID:15158148 PMID:15496615 PMID:16169029 PMID:17309078 PMID:17574045 PMID:18336854 PMID:18483861 PMID:18594523 PMID:18629305 PMID:18791325 PMID:19082730 PMID:19477266 PMID:19771260 PMID:20576514 PMID:20848084 PMID:21145380 PMID:21166495 PMID:21310227 PMID:21418039 PMID:21549813 PMID:21616140 PMID:22002103 PMID:22085843 PMID:22578287 PMID:22714038 PMID:23088786 PMID:23405080 PMID:23711929 PMID:23867903 PMID:24157283 PMID:24614525 PMID:24634002 PMID:25845326 PMID:25940438 PMID:26282491 PMID:27313093 PMID:27539140 PMID:28296042 PMID:28548367 PMID:28804952 PMID:28918123 PMID:29108775 PMID:29432840 PMID:29945211 PMID:29962303 PMID:30240709 PMID:30408460 PMID:30452899 PMID:30769050 PMID:30917517 PMID:31313457 PMID:31330229 PMID:31433961 PMID:32662599 PMID:34627931 PMID:35396826 PMID:29408335 PMID:32106377 More...
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RGD:127284846, RGD:127284886 |
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions increases expression decreases activity |
EXP ISO |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Carmustine results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Diclofenac results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dimethoate results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dimethylnitrosamine results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Zinc results in decreased expression of CAT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]] Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of CAT protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Ethanol results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased activity of CAT protein]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased activity of CAT protein] Acetylcysteine results in increased expression of CAT protein Acetylcysteine results in decreased activity of CAT protein [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Particulate Matter results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [ceric oxide results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Chlorine results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos affects the activity of CAT protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Propofol results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Smoke analog results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of CAT mRNA]; CAT protein inhibits the reaction [Acetylcysteine results in increased abundance of Hydrogen Peroxide] |
CTD |
PMID:7491977 PMID:16169029 PMID:19840221 PMID:19853593 PMID:20332008 PMID:21114986 PMID:21131394 PMID:22416658 PMID:22427991 PMID:23416263 PMID:24299490 PMID:24485406 PMID:24577230 PMID:24810974 PMID:26079211 PMID:26257840 PMID:26769589 PMID:27235710 PMID:27246665 PMID:28012895 PMID:28013216 PMID:28108387 PMID:28535741 PMID:28804952 PMID:29143438 PMID:30037311 PMID:30423402 PMID:30769050 PMID:30951941 PMID:30998386 PMID:31157476 PMID:32023790 PMID:32402895 PMID:34425170 PMID:34547296 PMID:34767868 PMID:35065218 PMID:35430258 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of CAV1 Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of CAV1 protein]; Acetylcysteine inhibits the reaction [Rosiglitazone results in increased expression of CAV1]; Acetylcysteine results in increased ubiquitination of and results in increased degradation of CAV1 protein; Hydrogen Peroxide inhibits the reaction [Acetylcysteine results in increased ubiquitination of and results in increased degradation of CAV1 protein] |
CTD |
PMID:18507034 PMID:21148404 PMID:35349355 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cbs |
cystathionine beta synthase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Rotenone results in decreased expression of CBS protein] |
CTD |
PMID:25086357 |
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NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions |
EXP ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CCL11 mRNA Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CCL11 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL11 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL11 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of CCL11 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of CCL11 protein] |
CTD |
PMID:12576300 PMID:22129741 PMID:26138014 |
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NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl17 |
C-C motif chemokine ligand 17 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CCL17 protein] |
CTD |
PMID:26138014 |
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NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Acetylcysteine inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CCL2 mRNA] Acetylcysteine affects the reaction [Doxorubicin results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]] Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]] |
CTD |
PMID:10541287 PMID:11124598 PMID:15139008 PMID:17529908 PMID:18303122 PMID:19158351 PMID:22700867 PMID:26332274 PMID:26683377 PMID:28555929 PMID:33146789 PMID:35065218 PMID:35123994 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of CCL20 mRNA |
CTD |
PMID:22385246 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of CCL22 mRNA] |
CTD |
PMID:19350554 |
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NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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G |
Ccl24 |
C-C motif chemokine ligand 24 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CCL24 protein] |
CTD |
PMID:26138014 |
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NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions decreases secretion |
ISO |
[Acetylcysteine co-treated with Particulate Matter] results in increased secretion of CCL3 protein; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CCL3 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL3 mRNA]; Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of CCL3 protein]]; Acetylcysteine promotes the reaction [Polymyxin B results in decreased secretion of CCL3 protein]; MYD88 protein affects the reaction [[Acetylcysteine co-treated with Particulate Matter] results in increased secretion of CCL3 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL3 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine results in decreased secretion of CCL3 protein] |
CTD |
PMID:21765237 PMID:28555929 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CCL5 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CCL5 mRNA] |
CTD |
PMID:10495789 PMID:11167962 PMID:26138014 PMID:33146789 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]; Cycloheximide inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein] Acetylcysteine results in increased expression of CCN1 mRNA; Acetylcysteine results in increased expression of CCN1 protein |
CTD |
PMID:21055460 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] |
CTD |
PMID:17270171 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccna1 |
cyclin A1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CCNA1 protein] |
CTD |
PMID:20654705 |
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NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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G |
Ccna2 |
cyclin A2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCNA2 protein] Acetylcysteine inhibits the reaction [alpha-terthienylmethanol results in increased expression of CCNA2 protein] |
CTD |
PMID:24909818 PMID:28506552 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]; Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CCNB1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]; Acetylcysteine inhibits the reaction [sinularin results in decreased phosphorylation of CCNB1 protein] |
CTD |
PMID:24909818 PMID:25633853 PMID:28548367 PMID:29128613 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [[Vorinostat co-treated with Butyrates] results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of CCND1 protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Hydrocarbons, Chlorinated analog results in increased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of CCND1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of CCND1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 protein] Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in decreased expression of CCND1 protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of CCND1 protein] |
CTD |
PMID:15173093 PMID:15897899 PMID:17602960 PMID:18563748 PMID:19409983 PMID:21600978 PMID:23948867 PMID:24355586 PMID:24909818 PMID:24968063 PMID:26332274 PMID:28321046 PMID:31433961 PMID:33485121 PMID:34627931 More...
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of CCND2 protein]; Acetylcysteine inhibits the reaction [Methoxychlor results in decreased expression of CCND2 mRNA] Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND2 protein] Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCND2 mRNA] |
CTD |
PMID:19615393 PMID:26332274 PMID:33485121 PMID:34627931 |
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NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccnd3 |
cyclin D3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND3 protein] |
CTD |
PMID:34627931 |
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NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of CCNE1 mRNA] Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCNE1 protein] |
CTD |
PMID:15945272 PMID:24909818 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccne2 |
cyclin E2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CCNE2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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G |
Cd14 |
CD14 molecule |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Iron deficiency results in increased expression of CD14 protein] |
CTD |
PMID:20368581 |
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd36 |
CD36 molecule |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNA] Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 protein]; CD36 mRNA promotes the reaction [Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased uptake of malondialdehyde-low density lipoprotein, human]] Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 protein] |
CTD |
PMID:22824115 PMID:26187465 PMID:33007364 PMID:35622622 PMID:36534932 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd40lg |
CD40 ligand |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CD40LG mRNA] Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein] |
CTD |
PMID:19477266 PMID:27634759 |
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NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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G |
Cd86 |
CD86 molecule |
multiple interactions |
ISO |
Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of CD86 protein]; Acetylcysteine inhibits the reaction [1,10-phenanthroline results in increased expression of CD86 mRNA]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Ethylmercuric Chloride results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Thimerosal results in increased expression of CD86 protein] |
CTD |
PMID:19033392 PMID:19641517 PMID:20417223 PMID:20457211 PMID:30842373 |
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NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cdc25c |
cell division cycle 25C |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CDC25C protein modified form] |
CTD |
PMID:25633853 |
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NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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G |
Cdh1 |
cadherin 1 |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; Acetylcysteine inhibits the reaction [DDT results in decreased expression of CDH1 mRNA]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased methylation of CDH1 promoter]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of CDH1 protein] Acetylcysteine results in increased expression of CDH1 protein Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in decreased expression of CDH1 protein] |
CTD |
PMID:18791180 PMID:22648416 PMID:24820114 PMID:28284859 PMID:32659284 PMID:32687844 PMID:32687961 PMID:34687772 More...
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh11 |
cadherin 11 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDH11 mRNA |
CTD |
PMID:22129741 |
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NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
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G |
Cdh13 |
cadherin 13 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of CDH13 mRNA |
CTD |
PMID:16084531 |
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NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
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G |
Cdh2 |
cadherin 2 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH2 protein] Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of CDH2 mRNA] |
CTD |
PMID:23876460 PMID:24820114 PMID:28284859 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdh5 |
cadherin 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein] |
CTD |
PMID:33131013 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CDK1 protein] Acetylcysteine inhibits the reaction [sinularin results in decreased phosphorylation of CDK1 protein] |
CTD |
PMID:25633853 PMID:28548367 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Methoxychlor results in decreased expression of CDK4 mRNA] Acetylcysteine inhibits the reaction [tubocapsenolide A results in increased degradation of CDK4 protein] |
CTD |
PMID:18442981 PMID:19615393 |
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NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdk7 |
cyclin-dependent kinase 7 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CDK7 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions decreases expression increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of CDKN1A]; Acetylcysteine inhibits the reaction [diaziquone results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [ethylenimine quinone results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1A enhancer]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]] Acetylcysteine results in decreased expression of CDKN1A mRNA Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [dihydrolipoic acid results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of CDKN1A protein] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDKN1A mRNA; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CDKN1A protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of CDKN1A protein] |
CTD |
PMID:8943236 PMID:9343371 PMID:12208374 PMID:15496615 PMID:15978937 PMID:17602960 PMID:18022818 PMID:19409983 PMID:21462292 PMID:21565247 PMID:22129741 PMID:22183962 PMID:22927544 PMID:24792323 PMID:26332274 PMID:26658076 PMID:30555576 PMID:32473187 PMID:33961949 PMID:35303175 PMID:36493885 More...
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression multiple interactions |
EXP ISO |
Acetylcysteine results in increased expression of CDKN1B protein Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of CDKN1B protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1B enhancer] Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of CDKN1B protein] |
CTD |
PMID:17602960 PMID:18022818 PMID:30917517 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [DNMT1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [EZH2 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [KDM2A protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [TET1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN2A protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN2A mRNA]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN2A mRNA]] Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN2A protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN2A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN2A protein] |
CTD |
PMID:31551408 PMID:32473187 PMID:35303175 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of CEBPA protein] Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CEBPA protein] |
CTD |
PMID:27117918 PMID:35622622 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA] |
CTD |
PMID:21220312 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cebpe |
CCAAT/enhancer binding protein epsilon |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]] |
CTD |
PMID:29945211 |
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NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of CFLAR protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of CFLAR protein]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in decreased expression of CFLAR protein modified form]] |
CTD |
PMID:25034532 PMID:25619640 PMID:34599545 |
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NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR protein] |
CTD |
PMID:19061877 |
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NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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G |
Chat |
choline O-acetyltransferase |
increases expression multiple interactions |
EXP |
Acetylcysteine results in increased expression of CHAT protein [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein] |
CTD |
PMID:25891525 |
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NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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G |
Chek1 |
checkpoint kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CHEK1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK1 protein]] Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CHEK1 protein modified form] |
CTD |
PMID:15489221 PMID:25633853 PMID:33971260 |
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NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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G |
Chek2 |
checkpoint kinase 2 |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CHEK2 protein modified form]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of CHEK2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased phosphorylation of CHEK2 protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased expression of CHEK2 protein] Acetylcysteine results in increased expression of CHEK2 protein |
CTD |
PMID:15489221 PMID:23274516 PMID:24792323 PMID:24933654 PMID:31715134 |
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NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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G |
Chka |
choline kinase alpha |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CHKA mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
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G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
multiple interactions |
EXP ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CHRM2 mRNA Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM2 mRNA] |
CTD |
PMID:22129741 PMID:29253600 |
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NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
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G |
Chrm3 |
cholinergic receptor, muscarinic 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM3 mRNA] |
CTD |
PMID:29253600 |
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NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
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G |
Chrm4 |
cholinergic receptor, muscarinic 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM4 mRNA] |
CTD |
PMID:29253600 |
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NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
decreases activity |
ISO |
Acetylcysteine results in decreased activity of CHUK protein |
CTD |
PMID:17395010 |
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Cish |
cytokine inducible SH2-containing protein |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CISH mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
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G |
Ckb |
creatine kinase B |
multiple interactions |
EXP |
[Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Acetaminophen results in decreased activity of CKB protein]; [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CKB protein] |
CTD |
PMID:19688255 |
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NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Ckm |
creatine kinase, M-type |
multiple interactions decreases secretion |
EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CKM mRNA] Acetylcysteine results in decreased secretion of CKM protein |
CTD |
PMID:9689591 PMID:21912612 |
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NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
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G |
Cldn1 |
claudin 1 |
multiple interactions |
EXP ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CLDN1 mRNA; Acetylcysteine inhibits the reaction [glyphosate results in decreased expression of CLDN1 protein] Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN1 mRNA] Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CLDN1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of CLDN1 protein] |
CTD |
PMID:22129741 PMID:28115242 PMID:29235125 PMID:32687961 PMID:33485121 PMID:34906888 More...
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NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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G |
Cldn4 |
claudin 4 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein] Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN4 mRNA] |
CTD |
PMID:23816505 PMID:33485121 |
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NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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G |
Cldn5 |
claudin 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of and affects the localization of CLDN5 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of CLDN5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CLDN5 protein] |
CTD |
PMID:28115242 PMID:34391839 |
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NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
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G |
Clec9a |
C-type lectin domain containing 9A |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CLEC9A mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:162,859,742...162,875,742
Ensembl chr 4:162,860,308...162,875,352
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G |
Clk1 |
CDC-like kinase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of CLK1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
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G |
Clu |
clusterin |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Chlorine results in increased expression of CLU protein] |
CTD |
PMID:35065218 |
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NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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G |
Cma1 |
chymase 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CMA1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
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G |
Cntf |
ciliary neurotrophic factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CNTF protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] |
CTD |
PMID:16896058 PMID:26138014 |
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NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
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G |
Col18a1 |
collagen type XVIII alpha 1 chain |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of COL18A1 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of COL18A1 protein] |
CTD |
PMID:13679210 |
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NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression multiple interactions |
ISO EXP |
Acetylcysteine results in decreased expression of COL1A1 mRNA Acetylcysteine results in decreased expression of COL1A1 mRNA; Acetylcysteine results in decreased expression of COL1A1 protein Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of COL1A1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 protein] Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of COL1A1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of COL1A1 protein] |
CTD |
PMID:11710721 PMID:17602960 PMID:32659284 PMID:34547296 PMID:36493885 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of COL1A2 mRNA |
CTD |
PMID:11710721 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col4a1 |
collagen type IV alpha 1 chain |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of COL4A1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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G |
Colq |
collagen like tail subunit of asymmetric acetylcholinesterase |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of COLQ mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of COLQ mRNA] |
CTD |
PMID:22129741 |
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NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107
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G |
Copg1 |
COPI coat complex subunit gamma 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of COPG1 mRNA] |
CTD |
PMID:34425375 |
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NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of COX4I1 mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of COX4I1 mRNA] |
CTD |
PMID:35403558 PMID:36493885 |
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NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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G |
Cpe |
carboxypeptidase E |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of CPE mRNA |
CTD |
PMID:16084531 |
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NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
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G |
Cplx1 |
complexin 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CPLX1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:1,184,677...1,216,392
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions |
EXP |
[Acetylcysteine co-treated with Dietary Fats] results in increased expression of CPT1A mRNA |
CTD |
PMID:21051528 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt1b |
carnitine palmitoyltransferase 1B |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CPT1B mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
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G |
Cradd |
CASP2 and RIPK1 domain containing adaptor with death domain |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of CRADD mRNA |
CTD |
PMID:16084531 |
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NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
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G |
Crat |
carnitine O-acetyltransferase |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CRAT mRNA |
CTD |
PMID:22129741 |
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NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of CREB1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of CREB1 protein] Acetylcysteine inhibits the reaction [4-biphenylamine results in increased expression of CREB1 protein] |
CTD |
PMID:18375950 PMID:32433928 PMID:36813253 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crem |
cAMP responsive element modulator |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CREM mRNA] |
CTD |
PMID:25381014 |
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NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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G |
Cry1 |
cryptochrome circadian regulator 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CRY1 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
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G |
Cryab |
crystallin, alpha B |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [arsenite results in increased expression of CRYAB protein] |
CTD |
PMID:15175009 |
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NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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G |
Cryga |
crystallin, gamma A |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CRYGA mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CRYGA mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 9:66,482,176...66,484,638
Ensembl chr 9:66,482,176...66,509,896
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G |
Cs |
citrate synthase |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of CS mRNA] Acetylcysteine promotes the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] |
CTD |
PMID:21775390 PMID:27385396 |
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NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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G |
Csf1 |
colony stimulating factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CSF1 mRNA] |
CTD |
PMID:35123994 |
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NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
ISO |
[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of ATP6V0D2 mRNA; [Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:30742845 |
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NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein] |
CTD |
PMID:10645887 PMID:19460412 PMID:26138014 PMID:29753051 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3r |
colony stimulating factor 3 receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]] |
CTD |
PMID:29945211 |
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NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881
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G |
Cst3 |
cystatin C |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CST3 protein] |
CTD |
PMID:35020164 |
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NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased phosphorylation of CTNNB1 protein] Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CTNNB1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in increased cleavage of CTNNB1 protein]; Acetylcysteine inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CTNNB1 protein] |
CTD |
PMID:16282376 PMID:19436114 PMID:24961358 PMID:24968063 PMID:28321046 PMID:28343033 PMID:33131013 More...
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctrc |
chymotrypsin C |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CTRC mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 5:154,147,314...154,156,540
Ensembl chr 5:154,147,316...154,156,528
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G |
Ctrl |
chymotrypsin-like |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [plumbagin results in decreased activity of CTRL protein] |
CTD |
PMID:31276663 |
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NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626
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G |
Ctsb |
cathepsin B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CTSB mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CTSB mRNA] |
CTD |
PMID:29307831 PMID:31319114 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsd |
cathepsin D |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of CTSD mRNA] |
CTD |
PMID:35550146 |
|
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Ctsk |
cathepsin K |
multiple interactions |
ISO |
[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:30742845 |
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NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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G |
Ctsl |
cathepsin L |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Berberine results in decreased cleavage of CTSL protein] |
CTD |
PMID:36070022 |
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NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Cux2 |
cut-like homeobox 2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CUX2 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CUX2 mRNA] |
CTD |
PMID:22129741 |
|
NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
decreases expression multiple interactions |
ISO EXP |
Acetylcysteine results in decreased expression of CXCL1 protein Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of CXCL1 protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein] |
CTD |
PMID:17395010 PMID:18257742 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CXCL12 protein] Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CXCL12 mRNA] |
CTD |
PMID:26138014 PMID:35123994 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of CXCL2 mRNA]; Acetylcysteine inhibits the reaction [Vanadates results in increased expression of CXCL2 mRNA] Acetylcysteine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CXCL2 protein] |
CTD |
PMID:10718115 PMID:16919916 PMID:19350554 PMID:21507677 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of CXCL1 protein Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]] |
CTD |
PMID:17395010 PMID:24316229 PMID:28555929 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CXCL6 protein] |
CTD |
PMID:26138014 |
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NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CYBA protein] |
CTD |
PMID:21195169 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CYBB protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CYBB protein] |
CTD |
PMID:21195169 PMID:29087013 |
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NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [dimethoxycurcumin affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [sodium arsenite affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [surfactin peptide affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein] Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of CYCS mRNA]; Acetylcysteine inhibits the reaction [Methylmercury Compounds affects the localization of CYCS protein] Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [CASP9 protein binds to CYCS protein]]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CYCS mRNA] Acetylcysteine results in decreased expression of CYCS protein |
CTD |
PMID:18483861 PMID:19536524 PMID:19954742 PMID:21145380 PMID:21221209 PMID:21549813 PMID:22085843 PMID:23711929 PMID:24634002 PMID:28296042 PMID:29248572 PMID:34547296 PMID:35123993 PMID:35396826 More...
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyct |
cytochrome c, testis |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Estradiol results in increased expression of CYCT protein] |
CTD |
PMID:15545282 |
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NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of CYP11A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein] |
CTD |
PMID:26769589 PMID:29567110 |
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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G |
Cyp11b2 |
cytochrome P450, family 11, subfamily b, polypeptide 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of CYP11B1 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of CYP11B1 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of CYP11B1 mRNA] |
CTD |
PMID:25617244 |
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NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
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G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of CYP11B2 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of CYP11B2 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of CYP11B2 mRNA] |
CTD |
PMID:25617244 |
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NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein] |
CTD |
PMID:29567110 |
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NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO EXP |
[Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] which results in decreased expression of NQO1 mRNA; Acetylcysteine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Acetylcysteine inhibits the reaction [1-(4-chlorophenyl)-benzo-2,5-quinone results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA] [Acetylcysteine co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]; Acetylcysteine affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Acetylcysteine affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased activity of CYP1A1 protein]; Acetylcysteine inhibits the reaction [beta-Naphthoflavone results in decreased activity of CYP1A1 protein]; Acetylcysteine inhibits the reaction [chromium trioxide results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Acetylcysteine promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of CYP1A1 mRNA; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of CYP1A1 mRNA] Acetylcysteine results in increased expression of CYP1A1 protein |
CTD |
PMID:15044633 PMID:15621696 PMID:16274885 PMID:19033395 PMID:20801209 PMID:21094198 PMID:21703343 PMID:22129741 PMID:25668756 PMID:26535918 PMID:27041069 PMID:29753051 PMID:29975444 PMID:30639957 PMID:30793600 PMID:34171359 PMID:35123993 More...
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
EXP ISO |
[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA] [CYP1A2 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite |
CTD |
PMID:21424224 PMID:22129741 PMID:23159886 PMID:27989148 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO EXP |
Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA] Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:21703343 PMID:22129741 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp26c1 |
cytochrome P450, family 26, subfamily C, polypeptide 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CYP26C1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:235,458,961...235,468,433
Ensembl chr 1:235,459,356...235,466,842
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
Acetylcysteine promotes the reaction [Phenobarbital results in increased expression of CYP2B1 mRNA] |
CTD |
PMID:11353799 PMID:14722249 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
multiple interactions |
ISO |
Acetylcysteine affects the reaction [CYP2C9 protein results in increased hydroxylation of bromfenac] |
CTD |
PMID:31815452 |
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NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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G |
Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
multiple interactions |
ISO |
[CYP2C19 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite |
CTD |
PMID:27989148 |
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NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
EXP ISO |
[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]; Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA] Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] Acetylcysteine inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA] |
CTD |
PMID:21424224 PMID:23159886 PMID:26332274 PMID:30423402 PMID:35713687 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
[CYP3A4 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite; Acetylcysteine inhibits the reaction [[CYP3A4 protein co-treated with neferine] results in decreased abundance of Glutathione] |
CTD |
PMID:25451576 PMID:27989148 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CYP4A1 mRNA; Acetylcysteine promotes the reaction [Bezafibrate results in increased expression of CYP4A1 mRNA] |
CTD |
PMID:19647067 PMID:22129741 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Dapk1 |
death associated protein kinase 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of DAPK1 mRNA] |
CTD |
PMID:19477266 |
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NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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G |
Ddhd1 |
DDHD domain containing 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DDHD1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression decreases expression multiple interactions |
ISO EXP |
Acetylcysteine results in increased expression of DDIT3 mRNA; Acetylcysteine results in increased expression of DDIT3 protein Acetylcysteine results in decreased expression of DDIT3 protein Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of DDIT3 protein] 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [(4-methyl-1-naphthyl)-(1-pentylindol-3-yl)methanone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3]; Acetylcysteine inhibits the reaction [CSC-3436 results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [discretamine results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Ethylmercury Compounds results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [ilimaquinone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [plumbagin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Quercetin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [rhododendrol results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [shogaol results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [shogaol results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tanshinone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [ursolic acid results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased expression of DDIT3 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]] Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Acetylcysteine promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 mRNA] |
CTD |
PMID:16084531 PMID:17171638 PMID:18077580 PMID:18384088 PMID:19722195 PMID:20493918 PMID:21145380 PMID:21198628 PMID:21266191 PMID:21533816 PMID:21616140 PMID:23339468 PMID:24157283 PMID:24291486 PMID:24394546 PMID:24612139 PMID:24802810 PMID:24930757 PMID:25341683 PMID:25451595 PMID:25568320 PMID:25817893 PMID:25950987 PMID:26203587 PMID:26772155 PMID:26867644 PMID:27484784 PMID:27511942 PMID:27634458 PMID:27658547 PMID:27784618 PMID:27816613 PMID:28296042 PMID:28754437 PMID:29111403 PMID:30502353 PMID:30508555 PMID:31276663 PMID:31330229 PMID:32506763 PMID:32578922 PMID:32590070 PMID:34599545 PMID:35622622 PMID:36252918 PMID:37072049 More...
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [withaferin A results in increased expression of DDIT4 protein] |
CTD |
PMID:21266191 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Defb18 |
defensin beta 18 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB18 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:20,852,230...20,853,247
Ensembl chr 9:20,852,300...20,853,211
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G |
Defb49 |
defensin beta 49 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB49 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DEFB49 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 9:20,832,686...20,837,352
Ensembl chr 9:20,832,686...20,837,352
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G |
Defb5 |
defensin beta 5 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of DEFB4A mRNA |
CTD |
PMID:22385246 |
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NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of DGAT2 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of DGAT2 protein] |
CTD |
PMID:33007364 |
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NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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G |
Dhfr |
dihydrofolate reductase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of DHFR mRNA] |
CTD |
PMID:36315628 |
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NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
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G |
Dhh |
desert hedgehog signaling molecule |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DHH mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
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G |
Dio2 |
iodothyronine deiodinase 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]] |
CTD |
PMID:18420745 |
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NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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G |
Dio3 |
iodothyronine deiodinase 3 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]] |
CTD |
PMID:18420745 |
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NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA] |
CTD |
PMID:28321046 |
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NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of DLG4 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of DLG4 protein] |
CTD |
PMID:27624276 PMID:28153600 |
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NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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G |
Dmrt1 |
doublesex and mab-3 related transcription factor 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DMRT1 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333
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G |
Dnah3 |
dynein, axonemal, heavy chain 3 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DNAH3 mRNA] |
CTD |
PMID:22129741 |
|
NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474
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G |
Dnai1 |
dynein, axonemal, intermediate chain 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DNAI1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:56,730,179...56,800,926
Ensembl chr 5:56,730,179...56,800,925
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of DNAJB1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of DNAJB4 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Acetylcysteine results in increased expression of DNAJB9 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnm1l |
dynamin 1-like |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [15-deoxyprostaglandin J2 affects the reaction [DNM1L protein binds to DNM1L protein binds to DNM1L protein binds to DNM1L protein]]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of DNM1L protein] Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate affects the localization of DNM1L protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the phosphorylation of DNM1L protein] |
CTD |
PMID:20307494 PMID:30641872 PMID:31408635 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions |
ISO |
[Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of DNMT1 mRNA; [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased methylation of DNMT1 promoter; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [DNMT1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of DNMT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DNMT1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DNMT1 protein] |
CTD |
PMID:29854080 PMID:31150806 PMID:31551408 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dnmt3b |
DNA methyltransferase 3 beta |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of DNMT3B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of DNMT3B protein] |
CTD |
PMID:26942697 PMID:31551408 |
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NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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G |
Dsp |
desmoplakin |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Dietary Fats results in increased expression of DSP mRNA] |
CTD |
PMID:21051528 |
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NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
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G |
Dspp |
dentin sialophosphoprotein |
increases expression |
ISO |
Acetylcysteine results in increased expression of DSPP mRNA |
CTD |
PMID:20951298 |
|
NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
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G |
Dusp1 |
dual specificity phosphatase 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DUSP1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DUSP1 protein] |
CTD |
PMID:18573614 |
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NCBI chr10:16,680,478...16,683,275
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G |
Dusp4 |
dual specificity phosphatase 4 |
increases expression |
ISO |
Acetylcysteine results in increased expression of DUSP4 mRNA |
CTD |
PMID:16084531 |
|
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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G |
Dut |
deoxyuridine triphosphatase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [beta-hydroxyisovalerylshikonin results in decreased phosphorylation of and results in decreased activity of DUT protein] |
CTD |
PMID:18078828 |
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NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
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G |
E2f1 |
E2F transcription factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of E2F1 protein] |
CTD |
PMID:16497787 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
Edn1 |
endothelin 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK3 protein] Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased secretion of EDN1 protein] Acetylcysteine inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA] |
CTD |
PMID:14623829 PMID:16261333 PMID:21765237 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Efcab3 |
EF-hand calcium binding domain 3 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EFCAB3 mRNA |
CTD |
PMID:22129741 |
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NCBI chr10:89,583,526...90,077,260
Ensembl chr10:89,644,522...90,077,259
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G |
Efna1 |
ephrin A1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EFNA1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
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G |
Efnb2 |
ephrin B2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of EFNB2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
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G |
Egf |
epidermal growth factor |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of EGF protein]; Acetylcysteine inhibits the reaction [cyadox results in increased expression of EGF]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA mRNA]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA protein] Acetylcysteine inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine]; Acetylcysteine inhibits the reaction [EGF protein results in increased abundance of Peroxides] |
CTD |
PMID:11158190 PMID:11214823 PMID:26138014 PMID:30265530 PMID:32092105 |
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NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of EGFR mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein] Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of EGFR protein] Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein] |
CTD |
PMID:10640773 PMID:14660655 PMID:15520183 PMID:15849355 PMID:16261333 PMID:17942915 PMID:21220312 PMID:23948867 PMID:26368632 PMID:26514923 PMID:28123000 More...
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egln1 |
egl-9 family hypoxia-inducible factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of EGLN1 mRNA] |
CTD |
PMID:36315628 |
|
NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
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G |
Egr1 |
early growth response 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of EGR1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of EGR1 mRNA] Acetylcysteine inhibits the reaction [platycodin D results in increased expression of EGR1 mRNA] |
CTD |
PMID:10625299 PMID:18804340 PMID:19010381 |
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of EGR2 mRNA] |
CTD |
PMID:19350554 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Ei24 |
EI24, autophagy associated transmembrane protein |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Tobacco Smoke Pollution results in increased expression of EI24 mRNA] |
CTD |
PMID:16137721 |
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NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
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G |
Eif2a |
eukaryotic translation initiation factor 2A |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased phosphorylation of EIF2A protein]] Acetylcysteine inhibits the reaction [Cadmium results in decreased phosphorylation of EIF2A protein] |
CTD |
PMID:21616140 PMID:25451595 PMID:27658547 PMID:29373603 |
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NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [chrysophanic acid results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pendulone results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine results in increased phosphorylation of and results in increased activity of EIF2AK3 protein Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2AK3 protein modified form] Acetylcysteine results in decreased expression of EIF2AK3 protein modified form Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:19722195 PMID:25341683 PMID:25451595 PMID:27484784 PMID:27784618 PMID:30300626 PMID:31330229 PMID:32506763 PMID:35288263 More...
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [chrysophanic acid results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of EIF2S1 protein] Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2S1 protein modified form] Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of EIF2S1 protein] |
CTD |
PMID:15788408 PMID:16324875 PMID:21911445 PMID:24291486 PMID:25568320 PMID:27484784 PMID:27634458 PMID:27709270 PMID:27816613 PMID:29380555 PMID:30300626 PMID:31330229 PMID:32506763 More...
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of EIF4EBP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] Acetylcysteine inhibits the reaction [frenolicin B results in decreased phosphorylation of EIF4EBP1 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased phosphorylation of EIF4EBP1 protein] |
CTD |
PMID:21195169 PMID:24299490 PMID:26804764 PMID:30661989 PMID:36709824 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Emilin2 |
elastin microfibril interfacer 2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EMILIN2 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352
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G |
Endog |
endonuclease G |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Acetylcysteine] affects the localization of ENDOG protein; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of ENDOG protein] |
CTD |
PMID:17309078 PMID:18034189 |
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NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
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G |
Eng |
endoglin |
increases expression |
ISO |
Acetylcysteine results in increased expression of ENG mRNA; Acetylcysteine results in increased expression of ENG protein |
CTD |
PMID:32947957 |
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NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Toluene 2,4-Diisocyanate results in increased secretion of ENPP2 protein] |
CTD |
PMID:26072274 |
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NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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G |
Enpp7 |
ectonucleotide pyrophosphatase/phosphodiesterase 7 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ENPP7 mRNA |
CTD |
PMID:22129741 |
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NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589
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G |
Entrep1 |
endosomal transmembrane epsin interactor 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ENTREP1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]] |
CTD |
PMID:19281832 |
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NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] |
CTD |
PMID:23958427 |
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NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Epb41 |
erythrocyte membrane protein band 4.1 |
multiple interactions |
EXP |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in decreased expression of EPB41 protein] |
CTD |
PMID:20946910 |
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NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821
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G |
Ephb1 |
Eph receptor B1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPHB1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839
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G |
Eps8 |
epidermal growth factor receptor pathway substrate 8 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPS8 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of ERCC1 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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G |
Ercc8 |
ERCC excision repair 8, CSA ubiquitin ligase complex subunit |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [dicrotophos results in decreased expression of ERCC8 protein] |
CTD |
PMID:28302478 |
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NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions decreases phosphorylation |
EXP ISO |
Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ERN1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased phosphorylation of ERN1 protein] Acetylcysteine results in decreased phosphorylation of ERN1 protein Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ERN1 protein modified form] Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]] |
CTD |
PMID:21198628 PMID:24394546 PMID:25451595 PMID:27784618 PMID:29373603 PMID:30633982 PMID:31330229 PMID:34687772 More...
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of ESR1 protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR1 mRNA] Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ESR1 protein] |
CTD |
PMID:18829485 PMID:26149760 PMID:32402895 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR2 mRNA] |
CTD |
PMID:18829485 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Esrra |
estrogen related receptor, alpha |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESRRA protein] |
CTD |
PMID:30104959 |
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NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of ETS1 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of ETS1 mRNA]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA] |
CTD |
PMID:21635667 |
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NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [EZH2 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of EZH2 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of EZH2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of EZH2 protein] |
CTD |
PMID:24582688 PMID:31551408 |
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NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
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G |
F13a1 |
coagulation factor XIII A1 chain |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of F13A1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA] |
CTD |
PMID:23114885 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of FABP4 protein] |
CTD |
PMID:27117918 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fadd |
Fas associated via death domain |
multiple interactions |
EXP ISO |
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of FADD protein] [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of FADD mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of FADD protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of FADD mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of FADD protein]] |
CTD |
PMID:20946910 PMID:35833596 |
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NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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G |
Fads2 |
fatty acid desaturase 2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FADS2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
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G |
Fam114a1 |
family with sequence similarity 114, member A1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr14:43,275,693...43,346,154
Ensembl chr14:43,275,701...43,346,174
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G |
Fam114a2 |
family with sequence similarity 114, member A2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr10:41,661,787...41,696,790
Ensembl chr10:41,661,787...41,696,741
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G |
Fam13a |
family with sequence similarity 13, member A |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM13A mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
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G |
Fam186a |
family with sequence similarity 186 member A |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM186A mRNA |
CTD |
PMID:22129741 |
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NCBI chr 7:131,043,586...131,102,312
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G |
Far1 |
fatty acyl CoA reductase 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAR1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of FAS mRNA] Acetylcysteine results in increased expression of FAS mRNA Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of FAS protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of FAS protein] |
CTD |
PMID:9227460 PMID:15382040 PMID:16169029 PMID:19014919 PMID:19477266 PMID:19720122 PMID:21741372 PMID:28219700 More...
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
multiple interactions increases expression |
ISO EXP |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of FASLG mRNA; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased expression of FASLG protein] Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of FASLG protein] [Atorvastatin co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein] Acetylcysteine results in increased expression of FASLG mRNA |
CTD |
PMID:11864783 PMID:17574045 PMID:19644561 PMID:19720122 PMID:19760616 PMID:20431929 PMID:20946910 PMID:22429591 PMID:26332274 PMID:28219700 More...
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fbxo32 |
F-box protein 32 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Indican results in increased expression of FBXO32 protein] |
CTD |
PMID:30849338 |
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NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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G |
Fen1 |
flap structure-specific endonuclease 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of FEN1 mRNA] |
CTD |
PMID:33971260 |
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NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
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G |
Fer1l5 |
fer-1-like family member 5 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FER1L5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:38,605,835...38,661,869
Ensembl chr 9:38,607,843...38,660,425
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G |
Fgf12 |
fibroblast growth factor 12 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FGF12 mRNA |
CTD |
PMID:22129741 |
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NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607
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G |
Fgf2 |
fibroblast growth factor 2 |
decreases expression multiple interactions |
ISO |
Acetylcysteine results in decreased expression of FGF2 mRNA Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in increased secretion of FGF2 protein] |
CTD |
PMID:16084531 PMID:19176594 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions |
EXP ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FGF21 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of FGF21 mRNA] Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of FGF21 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased secretion of FGF21 protein] |
CTD |
PMID:22129741 PMID:22917661 |
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NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgf6 |
fibroblast growth factor 6 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FGF6 protein] |
CTD |
PMID:26138014 |
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NCBI chr 4:159,854,913...159,863,447
Ensembl chr 4:159,854,913...159,863,447
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G |
Fgf7 |
fibroblast growth factor 7 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FGF7 protein] |
CTD |
PMID:26138014 |
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NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fhit |
fragile histidine triad diadenosine triphosphatase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of FHIT protein] |
CTD |
PMID:16585223 |
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NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
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G |
Filip1l |
filamin A interacting protein 1-like |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of FILIP1L mRNA |
CTD |
PMID:16084531 |
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NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of FKBP5 mRNA] |
CTD |
PMID:18829485 |
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NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Flg |
filaggrin |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FLG mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:178,884,793...178,912,986
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G |
Flna |
filamin A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of FLNA protein] |
CTD |
PMID:25944616 |
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NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of FLT1 protein Acetylcysteine inhibits the reaction [Cadmium results in increased expression of FLT1 mRNA]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of FLT1 mRNA] |
CTD |
PMID:17992120 PMID:29408318 |
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NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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G |
Flt3lg |
Fms related receptor tyrosine kinase 3 ligand |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FLT3LG protein] |
CTD |
PMID:26138014 |
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NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463
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G |
Fmr1 |
fragile X messenger ribonucleoprotein 1 |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] |
CTD |
PMID:27385396 |
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NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
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G |
Fn1 |
fibronectin 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Glucose results in increased expression of FN1 protein] Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP10 protein]; Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP13 protein]; Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP3 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of FN1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of FN1 mRNA] |
CTD |
PMID:16632126 PMID:17395008 PMID:22245600 PMID:22648416 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases activity |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOS]; Acetylcysteine inhibits the reaction [Etoposide results in increased expression of FOS]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased activity of FOS protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of FOS] Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [oxaliplatin results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [FOS protein co-treated with JUN protein]]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of FOS mRNA] Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in decreased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Carbon Tetrachloride results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of and results in increased phosphorylation of FOS protein]; Acetylcysteine promotes the reaction [bis(maltolato)oxovanadium(IV) results in decreased activity of [FOS protein binds to JUN protein]] Acetylcysteine results in decreased activity of FOS protein |
CTD |
PMID:7743507 PMID:8825185 PMID:8853906 PMID:9043100 PMID:9525474 PMID:10692565 PMID:14623829 PMID:15520183 PMID:16137721 PMID:17696279 PMID:19654923 PMID:20654705 PMID:22129741 PMID:23824011 PMID:24908156 PMID:36813253 More...
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOSL1 mRNA] |
CTD |
PMID:15520183 PMID:19010381 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Foxd2 |
forkhead box D2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 5:128,427,986...128,430,709
Ensembl chr 5:128,429,020...128,430,504
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G |
Foxd4 |
forkhead box D4 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD4 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:222,557,494...222,559,189
Ensembl chr 1:222,557,360...222,559,159
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G |
Foxm1 |
forkhead box M1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Thiostrepton results in decreased expression of FOXM1 protein] |
CTD |
PMID:22761781 |
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NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cyclosporine results in increased expression of and affects the localization of FOXO1 protein modified form]; Acetylcysteine inhibits the reaction [Glucose affects the localization of FOXO1 protein] |
CTD |
PMID:23765110 PMID:33450223 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Foxo3 |
forkhead box O3 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Simvastatin results in increased phosphorylation of FOXO3 protein] Acetylcysteine inhibits the reaction [tomentosin results in increased expression of FOXO3 protein] Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of FOXO3 protein] |
CTD |
PMID:20883752 PMID:23159718 PMID:25471227 PMID:30104959 PMID:30917517 PMID:34358621 More...
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Foxp3 |
forkhead box P3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of FOXP3 protein] |
CTD |
PMID:31900833 |
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NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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G |
Fshb |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of FSHB protein] |
CTD |
PMID:30633982 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Rotenone results in increased expression of FTH1 mRNA] Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of FTH1 protein] |
CTD |
PMID:18325346 PMID:32687844 |
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NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
Ftl1 |
ferritin light chain 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [arsenite results in increased expression of FTL1 protein] |
CTD |
PMID:15175009 |
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NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
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G |
Fto |
FTO, alpha-ketoglutarate dependent dioxygenase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of FTO mRNA] Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of FTO mRNA] |
CTD |
PMID:31004932 PMID:34425375 |
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NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
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G |
Fxn |
frataxin |
affects response to substance multiple interactions |
ISO |
Acetylcysteine affects the susceptibility to FXN protein mutant form Acetylcysteine affects the reaction [Ethanol affects the expression of FXN protein] |
CTD |
PMID:16120311 PMID:33017621 |
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NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of FYN protein] Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of FYN protein] |
CTD |
PMID:12902192 PMID:20850416 |
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NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of G6PC1 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions increases activity |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA] Acetylcysteine results in increased activity of G6PD protein |
CTD |
PMID:3099627 PMID:12717738 PMID:15225644 |
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NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
multiple interactions increases expression decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Formaldehyde results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [rhododendrol results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of GADD45A mRNA] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GADD45A mRNA; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GADD45A mRNA] Acetylcysteine results in increased expression of GADD45A mRNA Acetylcysteine results in decreased expression of GADD45A mRNA |
CTD |
PMID:18849615 PMID:22129741 PMID:24291486 PMID:26332274 PMID:26867644 |
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NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
multiple interactions |
EXP ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GADD45G mRNA Acetylcysteine inhibits the reaction [[xanthatin results in increased expression of GADD45G mRNA] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of GADD45G mRNA]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of GADD45G protein] |
CTD |
PMID:22129741 PMID:23313378 |
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NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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G |
Galntl5 |
polypeptide N-acetylgalactosaminyltransferase-like 5 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GALNTL5 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 4:9,873,426...9,923,297
Ensembl chr 4:9,873,428...9,923,136
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G |
Gap43 |
growth associated protein 43 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of GAP43 protein] |
CTD |
PMID:18375950 |
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NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
decreases expression multiple interactions |
EXP |
Acetylcysteine results in decreased expression of GAPDH mRNA Acetylcysteine inhibits the reaction [arsenite results in decreased expression of GAPDH protein] |
CTD |
PMID:11108245 PMID:15175009 |
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NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gata1 |
GATA binding protein 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
CTD |
PMID:10656287 |
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NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530
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G |
Gbp1 |
guanylate binding protein 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of GBP1 mRNA |
CTD |
PMID:16084531 |
|
NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 Ensembl chr 2:231,398,163...231,432,131
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Hydrocarbons, Chlorinated analog results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Indomethacin results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Sulindac results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of GCLC mRNA] Acetylcysteine inhibits the reaction [decamethrin results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of GCLC protein] Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA] |
CTD |
PMID:11820781 PMID:11909699 PMID:16631525 PMID:17540521 PMID:17980396 PMID:19328227 PMID:20851755 PMID:21728338 PMID:24355586 PMID:25263748 PMID:30951941 PMID:31029725 PMID:34036678 PMID:35123994 More...
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions affects response to substance |
ISO |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of GCLM mRNA]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of GCLM mRNA] GCLM protein affects the susceptibility to Acetylcysteine Acetylcysteine inhibits the reaction [arsenite results in increased expression of GCLM mRNA] |
CTD |
PMID:17584759 PMID:18723479 PMID:19328227 PMID:19350554 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gdf1 |
growth differentiation factor 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of GDF1 protein] Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of GDF1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of GDF1 protein] |
CTD |
PMID:33360347 |
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NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519
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G |
Gdf15 |
growth differentiation factor 15 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GDF15 mRNA] |
CTD |
PMID:35123994 |
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NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gdnf |
glial cell derived neurotrophic factor |
multiple interactions |
EXP ISO |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GDNF mRNA Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of GDNF protein] |
CTD |
PMID:22129741 PMID:26138014 |
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NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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G |
Gfap |
glial fibrillary acidic protein |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein] Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of GFAP protein] |
CTD |
PMID:28499986 PMID:31173782 |
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NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GGT1 mRNA; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased secretion of GGT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]; Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of GGT1 protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]] |
CTD |
PMID:12030384 PMID:22129741 PMID:24485406 PMID:24634002 |
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NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [glyphosate results in decreased expression of GJA1 protein] |
CTD |
PMID:34906888 |
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Gja4 |
gap junction protein, alpha 4 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of GJA4 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
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G |
Gjb1 |
gap junction protein, beta 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of GJB1 mRNA] |
CTD |
PMID:32142722 |
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NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
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G |
Gk |
glycerol kinase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Malathion results in increased activity of GK protein] |
CTD |
PMID:25449180 |
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NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
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G |
Gkn2 |
gastrokine 2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GKN2 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 4:119,778,326...119,824,366
Ensembl chr 4:119,818,280...119,824,363
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G |
Glb1 |
galactosidase, beta 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased activity of GLB1 protein]; Acetylcysteine inhibits the reaction [lopinavir-ritonavir drug combination results in increased activity of GLB1 protein]; Acetylcysteine inhibits the reaction [Ritonavir results in increased activity of GLB1 protein] |
CTD |
PMID:20884875 PMID:31551408 |
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NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
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G |
Glcci1 |
glucocorticoid induced 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GLCCI1 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 4:36,307,956...36,635,614
Ensembl chr 4:36,307,903...36,635,612
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein] |
CTD |
PMID:22925809 |
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NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
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G |
Glrx |
glutaredoxin |
affects response to substance |
ISO |
GLRX protein affects the susceptibility to Acetylcysteine |
CTD |
PMID:17468103 |
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NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of GLUD1 mRNA] |
CTD |
PMID:31857147 |
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NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
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G |
Gnai2 |
G protein subunit alpha i2 |
multiple interactions |
ISO EXP |
Acetylcysteine affects the reaction [IER3 protein affects the expression of GNAI2 mRNA] Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein] |
CTD |
PMID:18441196 PMID:20713914 |
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NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
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G |
Gnai3 |
G protein subunit alpha i3 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] |
CTD |
PMID:18441196 |
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NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
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G |
Gp1ba |
glycoprotein Ib platelet subunit alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [THPO protein results in increased expression of GP1BA protein] |
CTD |
PMID:20523355 |
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NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
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G |
Gp2 |
glycoprotein 2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GP2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 1:173,797,057...173,812,619
Ensembl chr 1:173,797,057...173,812,619
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G |
Gpbar1 |
G protein-coupled bile acid receptor 1 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPBAR1 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 9:75,860,758...75,863,260
Ensembl chr 9:75,860,677...75,863,168
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G |
Gpc5 |
glypican 5 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPC5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPC5 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282
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G |
Gpr153 |
G protein-coupled receptor 153 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR153 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 5:162,781,587...162,792,975
Ensembl chr 5:162,781,587...162,792,971
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G |
Gpr20 |
G protein-coupled receptor 20 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR20 mRNA |
CTD |
PMID:22129741 |
|
NCBI chr 7:105,601,761...105,611,959
Ensembl chr 7:105,602,368...105,603,430
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G |
Gpr55 |
G protein-coupled receptor 55 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR55 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPR55 mRNA] |
CTD |
PMID:22129741 |
|
NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [PTEN gene mutant form results in increased secretion of GPT protein]]; IL22 protein promotes the reaction [Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GPT protein]] [Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen affects the activity of GPT protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Cyclosporine results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]] |
CTD |
PMID:17461432 PMID:20688495 PMID:20804811 PMID:23375450 PMID:24485406 PMID:27022031 PMID:27720869 PMID:28435131 PMID:28887131 PMID:29704510 PMID:30423402 PMID:30641872 PMID:32402895 More...
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA] Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased expression of GPX1 mRNA]; Acetylcysteine inhibits the reaction [raspberry ketone results in decreased expression of GPX1 protein]; Acetylcysteine inhibits the reaction [rhododendrol results in decreased expression of GPX1 protein] Acetylcysteine results in increased expression of GPX1 protein Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of GPX1 protein] |
CTD |
PMID:25341683 PMID:26867644 PMID:30037311 PMID:30104959 PMID:35112789 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of GPX4 mRNA] |
CTD |
PMID:12208374 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Pilocarpine results in increased expression of GRIN2B protein] |
CTD |
PMID:22824136 |
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NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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G |
Grm2 |
glutamate metabotropic receptor 2 |
increases activity |
ISO |
Acetylcysteine results in increased activity of GRM2 protein |
CTD |
PMID:19136971 |
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NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
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G |
Grm3 |
glutamate metabotropic receptor 3 |
increases activity |
ISO |
Acetylcysteine results in increased activity of GRM3 protein |
CTD |
PMID:19136971 |
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NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
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G |
Grm5 |
glutamate metabotropic receptor 5 |
increases activity |
ISO |
Acetylcysteine results in increased activity of GRM5 protein |
CTD |
PMID:19136971 |
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NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
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G |
Gsdmd |
gasdermin D |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of GSDMD protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]] Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of GSDMD protein] Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD protein] |
CTD |
PMID:30378427 PMID:34791735 PMID:36347317 PMID:36354081 |
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NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of GSK3B protein] [Acetylcysteine co-treated with Chlorpyrifos] results in increased activity of GSK3B protein; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:18569013 PMID:19126599 PMID:24968063 PMID:25246272 PMID:27658547 PMID:33131013 PMID:33930485 More...
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of GSR mRNA]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in decreased expression of GSR mRNA] [Acetylcysteine co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein; [Acetylcysteine co-treated with Paraquat] results in increased activity of GSR protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide inhibits the reaction [GSR protein results in increased oxidation of NADP]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of GSR mRNA]; Acetylcysteine inhibits the reaction [Dimethylnitrosamine results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of GSR protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [EUK-134 results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]] |
CTD |
PMID:16631525 PMID:19840221 PMID:21114986 PMID:23159886 PMID:24634002 PMID:25724285 PMID:26079211 PMID:30951941 More...
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of GSTA1 mRNA] |
CTD |
PMID:9152014 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Gsta4 |
glutathione S-transferase alpha 4 |
multiple interactions |
EXP |
[Acetylcysteine co-treated with EUK-134] promotes the reaction [[Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Paraquat results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Zinc Sulfate results in increased activity of GSTA4 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Maneb results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Maneb results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA] |
CTD |
PMID:23159886 PMID:25724285 PMID:30639957 |
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NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
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G |
Gsta5 |
glutathione S-transferase alpha 5 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTA5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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G |
Gstm1 |
glutathione S-transferase mu 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA |
CTD |
PMID:21871945 PMID:22129741 |
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
Gstm2 |
glutathione S-transferase mu 2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTP1 mRNA] |
CTD |
PMID:22129741 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gulp1 |
GULP PTB domain containing engulfment adaptor 1 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of GULP1 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005
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G |
Gypa |
glycophorin A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] |
CTD |
PMID:20523355 |
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NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822
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G |
H2ax |
H2A.X variant histone |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [4-biphenylamine results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl)imidazole results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [[fludarabine co-treated with LAQ824] results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [alpha-terthienylmethanol results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [captax results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [chloropicrin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [Crizotinib results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [eprenetapopt results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [LAQ824 results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [manumycin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [PCB 180 metabolite results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [phenanthridone results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [Plant Extracts results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [polyhexamethyleneguanidine results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased expression of H2AX protein] Acetylcysteine results in increased expression of H2AX protein Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [yttrium chloride results in increased phosphorylation of H2AX protein] Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased activity of H2AX protein] |
CTD |
PMID:15173094 PMID:15489221 PMID:18852132 PMID:19409983 PMID:21135414 PMID:22172632 PMID:23274516 PMID:24614525 PMID:25633853 PMID:26079211 PMID:26148434 PMID:28300663 PMID:28506552 PMID:28993908 PMID:29128613 PMID:29416738 PMID:30408460 PMID:30917517 PMID:31157515 PMID:31168028 PMID:31639374 PMID:31682804 PMID:31715134 PMID:31884112 PMID:32433928 PMID:33031904 PMID:33961949 PMID:33971260 PMID:35088107 PMID:35123993 PMID:35279910 PMID:37072049 More...
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NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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G |
Has2 |
hyaluronan synthase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA] |
CTD |
PMID:21220312 |
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NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 protein] |
CTD |
PMID:35020164 |
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NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hax1 |
HCLS1 associated protein X-1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of HAX1 protein] |
CTD |
PMID:19679660 |
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NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [vanadium pentoxide results in increased expression of HBEGF mRNA] |
CTD |
PMID:12676768 |
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NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hectd4 |
HECT domain E3 ubiquitin protein ligase 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Ethanol results in increased expression of HECTD4 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of HECTD4 mRNA] |
CTD |
PMID:31004932 PMID:35713687 |
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NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987
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G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression multiple interactions |
ISO |
Acetylcysteine results in increased expression of HERPUD1 mRNA Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HERPUD1 mRNA] |
CTD |
PMID:16084531 PMID:18723479 |
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NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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G |
Hgf |
hepatocyte growth factor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of HGF protein] |
CTD |
PMID:16757516 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hhip |
Hedgehog-interacting protein |
multiple interactions |
EXP |
[Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of HHIP mRNA |
CTD |
PMID:21051528 |
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NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein] 1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Cisplatin affects the localization of HIF1A protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of HIF1A mRNA]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]] Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Nickel analog results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]] |
CTD |
PMID:10866824 PMID:11641398 PMID:11886167 PMID:13679210 PMID:16530163 PMID:17015263 PMID:17066447 PMID:17658243 PMID:19374849 PMID:19410601 PMID:21036805 PMID:22648416 PMID:22700867 PMID:25406100 PMID:27297870 PMID:29408318 PMID:31850806 PMID:35430258 PMID:36709824 More...
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hk2 |
hexokinase 2 |
increases expression |
ISO |
Acetylcysteine results in increased expression of HK2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
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G |
Hmbs |
hydroxymethylbilane synthase |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
CTD |
PMID:10656287 |
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NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
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G |
Hmga2 |
high mobility group AT-hook 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMGA2 protein] |
CTD |
PMID:27071802 |
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NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HMGB1 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of HMGB1 protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein] |
CTD |
PMID:26079697 PMID:30977640 PMID:36055550 |
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NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmgb2 |
high mobility group box 2 |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of HMGB2 mRNA |
CTD |
PMID:22129741 |
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NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR mRNA] |
CTD |
PMID:19931295 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmox1 |
heme oxygenase 1 |
increases expression affects activity multiple interactions |
ISO EXP |
Acetylcysteine results in increased expression of HMOX1 protein Acetylcysteine results in increased expression of HMOX1 mRNA; Acetylcysteine results in increased expression of HMOX1 protein Acetylcysteine affects the activity of HMOX1 protein [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; Acetylcysteine affects the reaction [Glucose affects the expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Oxidopamine results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [oxophenylarsine results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein] [Acetylcysteine results in increased abundance of Glutathione] inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine affects the reaction [Chlorpyrifos affects the expression of HMOX1 protein]; Acetylcysteine affects the reaction [Pyruvaldehyde affects the expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-butenal results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-xylene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of arsenite] which results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[tin protoporphyrin IX results in decreased activity of HMOX1 protein] which results in increased chemical synthesis of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Ammonium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Benzene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [chloropicrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [gallium nitrate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [lead acetate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of HMOX1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Polychlorinated Biphenyls analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ritonavir results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ritonavir results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Silicon analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Silver analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [tetrathiomolybdate analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Toluene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Oxygen results in increased expression of HMOX1 mRNA] Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [2,2'-dihydroxychalcone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide results in increased abundance of Peroxides] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[chromium trioxide co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Curcumin co-treated with piperine] results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid results in increased abundance of Peroxides] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [carnosol results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [chromium trioxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal results in increased expression of HMOX1]; Acetylcysteine inhibits the reaction [Hemin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Quercetin analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Urea results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein]; Polymyxin B inhibits the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 mRNA]] |
CTD |
PMID:7538129 PMID:9152014 PMID:9545559 PMID:9747510 PMID:10975858 PMID:11103787 PMID:11592956 PMID:12420312 PMID:12690112 PMID:12699905 PMID:12763371 PMID:14687664 PMID:15175009 PMID:15368090 PMID:15541757 PMID:16137721 PMID:16171798 PMID:16274885 PMID:16631525 PMID:16806455 PMID:16890772 PMID:16959797 PMID:17540521 PMID:17979524 PMID:18077580 PMID:18156441 PMID:18332044 PMID:18336854 PMID:18357586 PMID:18586083 PMID:18723479 PMID:18830972 PMID:19033392 PMID:19136476 PMID:19323979 PMID:19350554 PMID:19642688 PMID:19654923 PMID:20020861 PMID:20054154 PMID:20934533 PMID:20938987 PMID:21144877 PMID:21238556 PMID:21384399 PMID:21397656 PMID:21787718 PMID:22019695 PMID:22263782 PMID:22507881 PMID:22564156 PMID:22643931 PMID:22659318 PMID:22714038 PMID:22917016 PMID:23290930 PMID:23900960 PMID:23942037 PMID:24126012 PMID:24291486 PMID:24355171 PMID:24361488 PMID:24401988 PMID:24489685 PMID:25003661 PMID:25246272 PMID:26163453 PMID:26169828 PMID:26291278 PMID:26404762 PMID:26542248 PMID:26658076 PMID:26945724 PMID:26968795 PMID:27151894 PMID:27393915 PMID:27658547 PMID:27725188 PMID:27777014 PMID:27867098 PMID:28013216 PMID:28555929 PMID:29086419 PMID:29111403 PMID:29155359 PMID:29540228 PMID:30104959 PMID:30349652 PMID:30633982 PMID:30951941 PMID:30965051 PMID:31029725 PMID:31272005 PMID:31790703 PMID:31884112 PMID:32023790 PMID:32525552 PMID:32708634 PMID:33930485 PMID:34036678 PMID:35123994 PMID:36813253 More...
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf4g |
hepatocyte nuclear factor 4, gamma |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of HNF4G mRNA |
CTD |
PMID:22129741 |
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NCBI chr 2:97,885,773...98,036,650
Ensembl chr 2:97,887,432...98,036,592
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of HRAS mRNA] Acetylcysteine inhibits the reaction [HRAS protein mutant form results in increased susceptibility to sodium arsenite] |
CTD |
PMID:15945272 PMID:25199681 |
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NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hsbp1 |
heat shock factor binding protein 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Thioacetamide results in increased expression of HSBP1 protein] |
CTD |
PMID:17103249 |
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NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821
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G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD11B2 mRNA] |
CTD |
PMID:18829485 |
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NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of HSD17B3 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA] |
CTD |
PMID:26769589 PMID:29567110 |
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NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
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G |
Hsd17b8 |
hydroxysteroid (17-beta) dehydrogenase 8 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD17B8 mRNA] |
CTD |
PMID:18829485 |
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NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
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G |
Hsd3b3 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of HSD3B3 mRNA] |
CTD |
PMID:26769589 |
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NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
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G |
Hsf1 |
heat shock transcription factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased activity of HSF1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter affects the localization of HSF1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HSF1 promoter]]; Acetylcysteine inhibits the reaction [Vehicle Emissions affects the localization of HSF1 protein] |
CTD |
PMID:10403520 PMID:17922515 PMID:30309986 |
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NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSP90B1 mRNA]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of HSP90B1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSP90B1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSP90B1 protein] Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HSP90B1 protein] Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of HSP90B1 protein] |
CTD |
PMID:21145380 PMID:21533816 PMID:21911445 PMID:25451595 PMID:25950987 PMID:31330229 More...
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HSPA1B mRNA] Acetylcysteine inhibits the reaction [arsenite results in increased expression of HSPA1B protein] |
CTD |
PMID:15175009 PMID:18723479 |
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NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HSPA1A mRNA]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HSPA1A protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of HSPA1A mRNA] Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSPA1A protein] |
CTD |
PMID:12231548 PMID:16324719 PMID:18723479 PMID:36813253 |
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NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions decreases expression |
ISO EXP |
Acetylcysteine results in increased expression of HSPA5 protein Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [(4-methyl-1-naphthyl)-(1-pentylindol-3-yl)methanone results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [discretamine results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Ethylmercury Compounds affects the expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [ursolic acid results in increased expression of HSPA5 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]] Acetylcysteine results in decreased expression of HSPA5 protein Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of HSPA5 protein] |
CTD |
PMID:19722195 PMID:20493918 PMID:21145380 PMID:21198628 PMID:21533816 PMID:21911445 PMID:24157283 PMID:24291486 PMID:24802810 PMID:25341683 PMID:25451595 PMID:25950987 PMID:26772155 PMID:27484784 PMID:27511942 PMID:27784618 PMID:27816613 PMID:28296042 PMID:28754437 PMID:30502353 PMID:30633982 PMID:31276663 PMID:31330229 PMID:32506763 PMID:32590070 PMID:34687772 More...
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [arsenite results in increased expression of HSPB1 protein] |
CTD |
PMID:15175009 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [Chlorine results in increased expression of HSPD1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of HSPD1 mRNA] |
CTD |
PMID:32092105 PMID:35065218 |
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NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Htatip2 |
HIV-1 Tat interactive protein 2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of HTATIP2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
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G |
Icam1 |
intercellular adhesion molecule 1 |
affects expression multiple interactions decreases expression |
ISO EXP |
Acetylcysteine affects the expression of ICAM1 Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ICAM1 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased secretion of ICAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] Acetylcysteine results in decreased expression of ICAM1 mRNA Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of ICAM1 mRNA] Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Tin Fluorides results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 protein] |
CTD |
PMID:10495789 PMID:10792388 PMID:11736926 PMID:17416599 PMID:17666914 PMID:19642688 PMID:20885979 PMID:22093110 PMID:23114885 PMID:25876056 PMID:26683377 PMID:26901245 PMID:29329563 PMID:30842373 PMID:35349355 More...
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id2 |
inhibitor of DNA binding 2 |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of ID2 mRNA |
CTD |
PMID:16084531 |
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NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of IDH2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDH2 protein] |
CTD |
PMID:30104959 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Ier3 |
immediate early response 3 |
multiple interactions affects response to substance |
ISO |
Acetylcysteine affects the reaction [IER3 protein affects the expression of GNAI2 mRNA] IER3 protein affects the susceptibility to Acetylcysteine |
CTD |
PMID:20713914 |
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NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ier5 |
immediate early response 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of IER5 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]] |
CTD |
PMID:34051100 |
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NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IFNG protein]; Acetylcysteine inhibits the reaction [Eosine I Bluish results in increased expression of IFNG mRNA]; Acetylcysteine inhibits the reaction [Formaldehyde results in decreased expression of IFNG mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IFNG protein] Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IFNG protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein] Acetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA] |
CTD |
PMID:12847270 PMID:15004186 PMID:18849615 PMID:20431929 PMID:22440610 PMID:24810974 PMID:26138014 PMID:32620109 More...
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of IFRD1 mRNA] |
CTD |
PMID:18723479 |
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NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of IRS1 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IGF1 protein] |
CTD |
PMID:17458902 PMID:26138014 |
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IGF1R protein] |
CTD |
PMID:21195169 |
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NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
multiple interactions |
EXP ISO |
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of IGFBP1 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IGFBP1 protein] |
CTD |
PMID:22129741 PMID:26138014 |
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NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of IGFBP2 protein] |
CTD |
PMID:26138014 |
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NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of IGFBP4 protein] |
CTD |
PMID:26138014 |
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NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
decreases activity multiple interactions |
ISO |
Acetylcysteine results in decreased activity of IKBKB protein Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein] |
CTD |
PMID:17395010 PMID:34310962 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO EXP |
[Eugenol co-treated with Acetylcysteine] inhibits the reaction [Nicotine results in decreased secretion of IL10 protein]; Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Nicotine results in decreased expression of IL10 mRNA] Acetylcysteine inhibits the reaction [Methotrexate results in decreased secretion of IL10 protein]; Acetylcysteine promotes the reaction [Doxorubicin results in increased expression of IL10 mRNA] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL10 protein] |
CTD |
PMID:11124598 PMID:20431929 PMID:20885979 PMID:21237301 PMID:21424515 PMID:26138014 PMID:32620109 More...
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il10rb |
interleukin 10 receptor subunit beta |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of IL10RB mRNA |
CTD |
PMID:16084531 |
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NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074
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G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] |
CTD |
PMID:21237301 |
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NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] |
CTD |
PMID:21237301 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il13 |
interleukin 13 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL13 protein] |
CTD |
PMID:26138014 |
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NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Il15 |
interleukin 15 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL15 protein] |
CTD |
PMID:26138014 |
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NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
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G |
Il16 |
interleukin 16 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL16 protein] |
CTD |
PMID:26138014 |
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NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
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G |
Il17a |
interleukin 17A |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL17A protein]; Acetylcysteine inhibits the reaction [Trichloroethylene results in increased expression of IL17A mRNA] |
CTD |
PMID:20431929 PMID:23993974 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il17d |
interleukin 17D |
multiple interactions |
EXP |
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of IL17D mRNA |
CTD |
PMID:22129741 |
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NCBI chr15:31,671,337...31,688,833
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G |
Il18 |
interleukin 18 |
multiple interactions |
ISO EXP |
Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL18 protein] Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL18 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL18 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]] Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] |
CTD |
PMID:27311643 PMID:30205151 PMID:34510229 PMID:34791735 PMID:35020164 PMID:35285579 PMID:35777681 PMID:36055550 More...
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
[Acetylcysteine co-treated with IL1A protein] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [butylphen results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]; Acetylcysteine promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]] |
CTD |
PMID:7476933 PMID:24570342 PMID:26138014 PMID:28836394 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions affects expression decreases expression |
EXP ISO |
Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL1B protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Buthionine Sulfoximine co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B protein] Acetylcysteine affects the expression of IL1B protein Acetylcysteine results in decreased expression of IL1B mRNA [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL1B mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL1B protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased secretion of IL1B protein] [Acetylcysteine co-treated with Cobalt] results in decreased expression of IL1B protein; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein modified form]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [2,4-decadienal results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[IL1B protein co-treated with Oligomycins] results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[Oligomycins co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Cobalt results in increased expression of IL1B protein modified form]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; Acetylcysteine inhibits the reaction [IL1B protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL1B mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of IL1B protein modified form]; Acetylcysteine inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [xanthohumol results in increased expression of IL1B protein]; Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Acetylcysteine promotes the reaction [titanium dioxide results in increased secretion of IL1B protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]] |
CTD |
PMID:10541287 PMID:11970852 PMID:16014734 PMID:16214328 PMID:18257742 PMID:18403674 PMID:19281832 PMID:21424515 PMID:21703343 PMID:21779360 PMID:22385246 PMID:22549761 PMID:22867088 PMID:23159886 PMID:23900960 PMID:23940760 PMID:23948867 PMID:24570342 PMID:24609059 PMID:24810974 PMID:25406100 PMID:26086368 PMID:26138014 PMID:26332274 PMID:26435000 PMID:26809137 PMID:26901245 PMID:27311643 PMID:27393034 PMID:27783111 PMID:28004443 PMID:28814068 PMID:30205151 PMID:30320338 PMID:30639957 PMID:30878009 PMID:30977640 PMID:31629901 PMID:32620109 PMID:32687961 PMID:32805375 PMID:34238121 PMID:34510229 PMID:34791735 PMID:34863858 PMID:35190838 PMID:35285579 PMID:35349355 PMID:35833596 PMID:36055550 PMID:36347317 PMID:36354081 PMID:36493885 PMID:36880428 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
multiple interactions |
ISO EXP |
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of IL2 mRNA; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of IL2 protein] Acetylcysteine inhibits the reaction [Fenitrothion results in increased secretion of IL2 protein] |
CTD |
PMID:22429591 PMID:22910795 PMID:31173782 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il24 |
interleukin 24 |
decreases activity |
ISO |
Acetylcysteine results in decreased activity of IL24 protein |
CTD |
PMID:14678967 |
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NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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G |
Il27ra |
interleukin 27 receptor subunit alpha |
decreases expression |
ISO |
Acetylcysteine results in decreased expression of IL27RA mRNA |
CTD |
PMID:16084531 |
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NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938
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G |
Il2ra |
interleukin 2 receptor subunit alpha |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]] |
CTD |
PMID:23134680 |
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NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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G |
Il3 |
interleukin 3 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL3 protein] |
CTD |
PMID:26138014 |
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NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
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G |
Il33 |
interleukin 33 |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [Soot results in increased expression of IL33 mRNA] |
CTD |
PMID:35776887 |
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NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL4 protein] |
CTD |
PMID:26138014 PMID:27634759 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il4r |
interleukin 4 receptor |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL4R mRNA] |
CTD |
PMID:29753051 |
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NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
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G |
Il5 |
interleukin 5 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL5 protein] Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL5 protein] |
CTD |
PMID:20431929 PMID:26138014 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
EXP ISO |
Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL6 protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [[Buthionine Sulfoximine co-treated with Lipopolysaccharides] results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of IL6 protein] [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL6 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL6 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]] [Acetylcysteine co-treated with Ascorbic Acid] inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [calcium silicate results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; |