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Accession:CHEBI:77032 term browser browse the term
Definition:A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
Synonyms:exact_synonym: 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline
 related_synonym: 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine;   Fluibron;   Formula=C14H20Br2N2;   InChI=1S/C14H20Br2N2/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17/h7-8,12H,2-6,9,17H2,1H3;   InChIKey=OJGDCBLYJGHCIH-UHFFFAOYSA-N;   N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine;   SMILES=CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1;   bromhexina;   bromhexinum
 xref: Beilstein:2216008 "Beilstein";   CAS:3572-43-8 "ChemIDplus";   CAS:3572-43-8 "NIST Chemistry WebBook";   Drug_Central:402 "DrugCentral";   KEGG:D07542;   LINCS:LSM-3048
 xref_mesh: MESH:D001964
 xref: PMID:20031363 "Europe PMC";   PMID:22027391 "Europe PMC";   PMID:23781460 "Europe PMC";   PMID:4065592 "Europe PMC";   PMID:7027431 "Europe PMC";   PMID:7027873 "Europe PMC";   PMID:778563 "Europe PMC";   Patent:BE625022;   Wikipedia:Bromhexine
 cyclic_relationship: is_conjugate_base_of CHEBI:77040

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bromhexine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            mucolytic 840
              bromhexine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        aromatic amine 13572
                                          anilines 12285
                                            substituted aniline 11780
                                              bromhexine 2
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