beta-naphthoflavone - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	beta-naphthoflavone	go back to main search page
Accession:	CHEBI:77013	browse the term
Definition:	An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
Synonyms:	exact_synonym:	3-phenyl-1H-benzo[f]chromen-1-one
	related_synonym:	3-phenyl-1H-naphtho(2,1-b)pyran-1-one; 5,6-benzoflavone; Formula=C19H12O2; InChI=1S/C19H12O2/c20-16-12-18(14-7-2-1-3-8-14)21-17-11-10-13-6-4-5-9-15(13)19(16)17/h1-12H; InChIKey=OUGIDAPQYNCXRA-UHFFFAOYSA-N; SMILES=O=c1cc(oc2ccc3ccccc3c12)-c1ccccc1; benzo[f]flavone; beta-NF
	xref:	CAS:6051-87-2; DrugBank:DB06732
	xref_mesh:	MESH:D019324
	xref:	PMID:11697852; PMID:16730384; PMID:18535361; PMID:19969063; PMID:20060304; PMID:20843940; PMID:21624442; PMID:22167217; PMID:24163404; PMID:3924427; PMID:8430058; Reaxys:18991; Wikipedia:Beta-Naphthoflavone

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Genes (1123)

beta-naphthoflavone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-1-B glycoprotein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of A1BG mRNA

NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097

G

alpha-2-macroglobulin

decreases expression

beta-Naphthoflavone results in decreased expression of A2M mRNA

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

alpha 1,3-galactosyltransferase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of A3GALT2 mRNA

NCBI chr 5:141,101,329...141,113,760
Ensembl chr 5:141,107,983...141,115,641

G

arylacetamide deacetylase

decreases expression

beta-Naphthoflavone results in decreased expression of AADAC mRNA

NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734

G

ATP binding cassette subfamily B member 6

increases expression

beta-Naphthoflavone results in increased expression of ABCB6 mRNA

NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924

G

ATP binding cassette subfamily C member 1

increases expression

beta-Naphthoflavone results in increased expression of ABCC1 mRNA

NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114

G

ATP binding cassette subfamily C member 2

increases expression
decreases expression
multiple interactions

beta-Naphthoflavone results in increased expression of ABCC2 mRNA
beta-Naphthoflavone results in decreased expression of ABCC2 mRNA
[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC2 mRNA

PMID:11752103 PMID:15833929 PMID:16426233 PMID:19737606 PMID:20607812 More...

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

multiple interactions
increases expression

[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC3 mRNA
beta-Naphthoflavone results in increased expression of ABCC3 mRNA

PMID:15833929 PMID:19118567 PMID:23994337

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of ABCC4 mRNA

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily C member 5

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of ABCC5 mRNA
[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC5 mRNA

NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253

G

ATP binding cassette subfamily C member 6

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of ABCC6 mRNA
[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC6 mRNA

NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464

G

ATP binding cassette subfamily C member 9

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ABCC9 mRNA

NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356

G

ATP binding cassette subfamily E member 1

increases expression

beta-Naphthoflavone results in increased expression of ABCE1 mRNA

NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489

G

ATP binding cassette subfamily G member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ABCG1 mRNA

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

G

ATP binding cassette subfamily G member 2

increases expression

beta-Naphthoflavone results in increased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

acetyl-CoA carboxylase beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACACB mRNA

NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655

G

ArfGAP with coiled-coil, ankyrin repeat and PH domains 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACAP2 mRNA

NCBI chr11:69,538,487...69,654,156
Ensembl chr11:69,538,546...69,654,151

G

acetyl-CoA acetyltransferase 2

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACAT2 mRNA
beta-Naphthoflavone results in decreased expression of ACAT2 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of ACAT2 mRNA]

PMID:18164116 PMID:22234961 PMID:31225620

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

acyl-CoA binding domain containing 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACBD3 mRNA

NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380

G

angiotensin I converting enzyme

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACE mRNA

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

acyl-CoA thioesterase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACOT1 mRNA

NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA thioesterase 7

increases expression

beta-Naphthoflavone results in increased expression of ACOT7 mRNA

NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309

G

acyl-CoA synthetase long-chain family member 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACSL3 mRNA

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

activin A receptor like type 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACVRL1 mRNA
beta-Naphthoflavone results in decreased expression of ACVRL1 mRNA

PMID:18164116 PMID:32858204

NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591

G

aminoacylase 1

increases expression

beta-Naphthoflavone results in increased expression of ACY1 mRNA

NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682

G

ADAM metallopeptidase domain 12

decreases expression

beta-Naphthoflavone results in decreased expression of ADAM12 mRNA

NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667

G

ADAM metallopeptidase domain 19

decreases expression

beta-Naphthoflavone results in decreased expression of ADAM19 mRNA

NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105

G

ADAM metallopeptidase domain 2

increases expression

beta-Naphthoflavone results in increased expression of ADAM2 mRNA

NCBI chr15:40,242,651...40,284,025
Ensembl chr15:40,242,783...40,283,952

G

ADAM-like, decysin 1

increases expression

beta-Naphthoflavone results in increased expression of ADAMDEC1 mRNA

NCBI chr15:42,900,629...42,921,684
Ensembl chr15:42,900,636...42,921,712

G

adenylate cyclase 3

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADCY3 mRNA
beta-Naphthoflavone results in decreased expression of ADCY3 mRNA

PMID:18164116 PMID:32858204

NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686

G

adenylate cyclase 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ADCY8 mRNA

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

G

adhesion G protein-coupled receptor E5

decreases expression

beta-Naphthoflavone results in decreased expression of ADGRE5 mRNA

NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638

G

adhesion G protein-coupled receptor G1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADGRG1 mRNA
beta-Naphthoflavone results in decreased expression of ADGRG1 mRNA

PMID:18164116 PMID:32858204

NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108

G

adhesion G protein-coupled receptor G2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADGRG2 mRNA

NCBI chr X:34,297,402...34,422,590
Ensembl chr X:34,297,402...34,422,609

G

adhesion G protein-coupled receptor G6

decreases expression

beta-Naphthoflavone results in decreased expression of ADGRG6 mRNA

NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123

G

adhesion G protein-coupled receptor L2

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of ADGRL2 mRNA]

NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of ADH7 mRNA

NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182

G

alcohol dehydrogenase, iron containing, 1

decreases expression

beta-Naphthoflavone results in decreased expression of ADHFE1 mRNA

NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517

G

adrenomedullin

increases expression

beta-Naphthoflavone results in increased expression of ADM mRNA

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

G

adrenoceptor beta 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ADRB3 mRNA

NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552

G

ADRM1 26S proteasome ubiquitin receptor

increases expression

beta-Naphthoflavone results in increased expression of ADRM1 mRNA

NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195

G

alanine--glyoxylate aminotransferase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AGXT mRNA

NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336

G

aryl hydrocarbon receptor

affects binding
affects localization
decreases expression
increases expression
affects folding
multiple interactions
increases activity
affects response to substance

[beta-Naphthoflavone binds to AHR protein] which binds to ESR1 protein; [beta-Naphthoflavone binds to AHR protein] which binds to ESRRA protein; [beta-Naphthoflavone binds to AHR protein] which binds to NR2F1 protein; beta-Naphthoflavone binds to AHR protein
beta-Naphthoflavone affects the localization of AHR protein
beta-Naphthoflavone results in decreased expression of AHR mRNA; beta-Naphthoflavone results in decreased expression of AHR protein
beta-Naphthoflavone results in increased expression of AHR mRNA
beta-Naphthoflavone affects the folding of AHR protein
AHR protein promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of AHR mRNA]; beta-Naphthoflavone binds to and results in increased activity of AHR protein; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]
beta-Naphthoflavone results in increased activity of AHR protein
AHR protein affects the susceptibility to beta-Naphthoflavone
[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC2 mRNA; [beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC3 mRNA; [beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC5 mRNA; [beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC6 mRNA; [beta-Naphthoflavone binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [beta-Naphthoflavone binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [beta-Naphthoflavone results in increased activity of AHR protein]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of PPARA mRNA]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of PPARA protein]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of CSN2 mRNA]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of LALBA mRNA]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of WAP mRNA]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR promotes the reaction [beta-Naphthoflavone results in decreased abundance of Lactic Acid]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of ACAT2 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of ADGRL2 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CES2E mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CES3 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of COQ10B mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYB5B mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYP51 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of DHCR7 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of DMGDH mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FDFT1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FOS protein]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of GBP6 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HAGH mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCR mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCS1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HSD17B7 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of IDI1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of IRGM mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of LSS mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of MSMO1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of MVD mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of NAT8F2 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of NSDHL mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of PCSK9 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of PMVK mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of RCAN2 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of RDH11 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SERPINA7 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SQLE mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of UGCG mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of UBE2L3 mRNA]; AHR protein promotes the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; beta-Naphthoflavone binds to and affects the localization of AHR protein; beta-Naphthoflavone binds to and results in increased activity of AHR protein; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to BMAL1 protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to PER1 promoter]; beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]; kaempferol inhibits the reaction [beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]
AHR gene alternative form affects the susceptibility to beta-Naphthoflavone; AHR protein affects the susceptibility to beta-Naphthoflavone
[beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]; [beta-Naphthoflavone results in increased activity of AHR protein] which results in decreased chemical synthesis of and results in decreased secretion of Cholesterol; AHR gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]; AHR mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [FASLG protein binds to FASLG protein]]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FDFT1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCR mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of LSS mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SQLE mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone binds to and results in increased activity of AHR protein; beta-Naphthoflavone binds to and results in increased activity of AHR protein polymorphism; beta-Naphthoflavone binds to and results in increased activity of and results in increased localization of AHR protein; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; beta-Naphthoflavone promotes the reaction [[AHR protein binds to UGT1A1 enhancer] which results in increased expression of UGT1A1 mRNA]; beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to GSTA1 promoter]; beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]; Carbaryl inhibits the reaction [beta-Naphthoflavone binds to and results in increased activity of AHR protein]; cryptotanshinone promotes the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]; dihydrotanshinone I promotes the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]; NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]]; tanshinone promotes the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]

PMID:3005314 PMID:9407059 PMID:10620335 PMID:11752103 PMID:11752201 More...

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aryl-hydrocarbon receptor repressor

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AHRR mRNA
beta-Naphthoflavone results in increased expression of AHRR mRNA

PMID:12520768 PMID:18164116 PMID:25218365

NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673

G

adenylate kinase 4

decreases expression

beta-Naphthoflavone results in decreased expression of AK4 mRNA

NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618

G

aldo-keto reductase family 1 member A1

increases expression

beta-Naphthoflavone results in increased expression of AKR1A1 mRNA

NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674

G

aldo-keto reductase family 1, member C1

increases expression

beta-Naphthoflavone results in increased expression of AKR1C1 mRNA

PMID:17253728 PMID:32151702

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C15

increases expression

beta-Naphthoflavone results in increased expression of AKR1C8 mRNA

NCBI chr17:66,181,493...66,208,090
Ensembl chr17:66,181,493...66,208,061

G

aldo-keto reductase family 1, member C3

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of AKR1C3 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AKR1C18 mRNA

PMID:18164116 PMID:19737606 PMID:32151702

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

aldo-keto reductase family 1, member D1

decreases expression

beta-Naphthoflavone results in decreased expression of AKR1D1 mRNA

NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372

G

aldo-keto reductase family 1, member E2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AKR1E1 mRNA

NCBI chr17:65,735,909...65,750,441
Ensembl chr17:65,735,943...65,750,441

G

aldo-keto reductase family 7, member A2

increases expression

beta-Naphthoflavone results in increased expression of AKR7A2 mRNA; beta-Naphthoflavone results in increased expression of AKR7A2 protein

NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909

G

aldo-keto reductase family 7 member A3

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AKR7A3 mRNA
beta-Naphthoflavone results in increased expression of AKR7A3 mRNA

PMID:18164116 PMID:22687991

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

5'-aminolevulinate synthase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALAS2 mRNA

NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519

G

albumin

decreases expression

beta-Naphthoflavone results in decreased expression of ALB mRNA

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member A1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member B1

increases expression

beta-Naphthoflavone results in increased expression of ALDH1B1 mRNA

NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378

G

aldehyde dehydrogenase 3 family, member A1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of ALDH3A1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH3A1 mRNA

PMID:1416978 PMID:17998271 PMID:18164116 PMID:23994337 PMID:25218365 More...

NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681

G

aldehyde dehydrogenase 3 family, member B1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH3B1 mRNA

NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921

G

aldehyde dehydrogenase 3 family, member B2

decreases expression

beta-Naphthoflavone results in decreased expression of ALDH3B2 mRNA

NCBI chr 1:201,250,260...201,264,699
Ensembl chr 1:201,253,157...201,264,705

G

aldehyde dehydrogenase 3 family, member B3

decreases expression

beta-Naphthoflavone results in decreased expression of ALDH3B2 mRNA

NCBI chr 1:201,193,832...201,201,666
Ensembl chr 1:201,187,962...201,250,204

G

aldehyde dehydrogenase 8 family, member A1

decreases expression

beta-Naphthoflavone results in decreased expression of ALDH8A1 mRNA

NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385

G

arachidonate 5-lipoxygenase

increases expression

beta-Naphthoflavone results in increased expression of ALOX5 mRNA

NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743

G

alkaline phosphatase, biomineralization associated

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALPL mRNA

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

adenosine monophosphate deaminase 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AMPD3 mRNA

NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887

G

ankyrin repeat domain 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of ANKRD1 mRNA

NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919

G

acidic nuclear phosphoprotein 32 family member A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANP32A mRNA

NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443

G

annexin A1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA1 mRNA

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A4

decreases expression

beta-Naphthoflavone results in decreased expression of ANXA4 mRNA

NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161

G

annexin A5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA5 mRNA

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

annexin A8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA8 mRNA

NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043

G

amine oxidase, copper containing 1

decreases expression

beta-Naphthoflavone results in decreased expression of AOC1 mRNA

NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840

G

adaptor related protein complex 1 subunit sigma 1

increases expression

beta-Naphthoflavone results in increased expression of AP1S1 mRNA

NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713

G

amyloid P component, serum

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APCS mRNA

NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298

G

apelin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of APLN mRNA

NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391

G

apolipoprotein A4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APOA4 mRNA

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

G

apolipoprotein A5

decreases expression

beta-Naphthoflavone results in decreased expression of APOA5 mRNA

NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816

G

apolipoprotein B mRNA editing enzyme catalytic subunit 2

decreases expression

beta-Naphthoflavone results in decreased expression of APOBEC2 mRNA

NCBI chr 9:12,564,955...12,578,461
Ensembl chr 9:12,564,920...12,578,458

G

apolipoprotein M

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APOM mRNA

NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550

G

adenine phosphoribosyl transferase

increases expression

beta-Naphthoflavone results in increased expression of APRT mRNA

NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431

G

aprataxin

increases expression

beta-Naphthoflavone results in increased expression of APTX mRNA

NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855

G

Rho/Rac guanine nucleotide exchange factor 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ARHGEF2 mRNA

NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355

G

AT-rich interaction domain 5B

decreases expression

beta-Naphthoflavone results in decreased expression of ARID5B mRNA

NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433

G

ADP ribosylation factor like GTPase 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ARL3 mRNA

NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820

G

aryl hydrocarbon receptor nuclear translocator

multiple interactions

ARNT affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; ARNT promotes the reaction [beta-Naphthoflavone results in decreased abundance of Lactic Acid]; beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]; beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]; kaempferol inhibits the reaction [beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]
AHR gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]; beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]; beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]

PMID:17012224 PMID:19901195 PMID:21127131 PMID:21849270 PMID:24486526

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

aryl hydrocarbon receptor nuclear translocator 2

increases expression

beta-Naphthoflavone results in increased expression of ARNT2 mRNA

NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153

G

arrestin domain containing 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ARRDC2 mRNA

NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

increases expression

beta-Naphthoflavone results in increased expression of ASAP1 mRNA

NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

beta-Naphthoflavone results in increased expression of ASNS mRNA

PMID:17175557 PMID:32858204

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

atos homolog B

increases expression

beta-Naphthoflavone results in increased expression of ATOSB mRNA

NCBI chr 5:57,260,839...57,274,524
Ensembl chr 5:57,260,841...57,268,892

G

ATPase Na+/K+ transporting subunit beta 3

increases expression

beta-Naphthoflavone results in increased expression of ATP1B3 mRNA

NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598

G

ATPase plasma membrane Ca2+ transporting 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ATP2B2 mRNA

NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665

G

ATP synthase F1 subunit beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ATP5F1B protein; [Piperonyl Butoxide co-treated with beta-Naphthoflavone] results in decreased expression of ATP5F1B protein

NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273

G

ATPase H+ transporting V1 subunit B1

decreases expression

beta-Naphthoflavone results in decreased expression of ATP6V1B1 mRNA

NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475

G

ATPase H+ transporting V1 subunit C2

decreases expression

beta-Naphthoflavone results in decreased expression of ATP6V1C2 mRNA

NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028

G

ATPase copper transporting beta

decreases expression

beta-Naphthoflavone results in decreased expression of ATP7B mRNA

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

ataxin 10

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ATXN10 mRNA

NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087

G

AUP1, lipid droplet regulating VLDL assembly factor

increases expression

beta-Naphthoflavone results in increased expression of AUP1 mRNA

NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346

G

advillin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AVIL mRNA

NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071

G

acyl-CoA wax alcohol acyltransferase 1

decreases expression

beta-Naphthoflavone results in decreased expression of AWAT1 mRNA

NCBI chr X:65,668,205...65,674,450
Ensembl chr X:65,668,205...65,674,450

G

beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of B3GALNT1 mRNA

NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332

G

BAF nuclear assembly factor 1

decreases expression

beta-Naphthoflavone results in decreased expression of BANF1 mRNA

NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188

G

brain abundant, membrane attached signal protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BASP1 mRNA

NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043

G

branched chain amino acid transaminase 1

decreases expression

beta-Naphthoflavone results in decreased expression of BCAT1 mRNA

NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597

G

BCL2, apoptosis regulator

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of BCL2 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BCL2 mRNA

PMID:21295105 PMID:22687991

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL9 like

increases expression

beta-Naphthoflavone results in increased expression of BCL9L mRNA

NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611

G

brain expressed X-linked 3

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BEX3 mRNA
beta-Naphthoflavone results in decreased expression of BEX3 mRNA

PMID:18164116 PMID:32858204

NCBI chr X:99,273,270...99,274,799
Ensembl chr X:99,273,161...99,274,800

G

brain expressed, X-linked 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BEX4 mRNA

NCBI chr X:99,131,985...99,133,417
Ensembl chr X:99,131,942...99,133,531

G

biglycan

decreases expression

beta-Naphthoflavone results in decreased expression of BGN mRNA

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

basic helix-loop-helix family, member e41

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BHLHE41 mRNA

NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468

G

betaine-homocysteine S-methyltransferase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of BHMT mRNA

NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742

G

baculoviral IAP repeat-containing 3

increases expression

beta-Naphthoflavone results in increased expression of BIRC3 mRNA

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BIRC5 mRNA

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

B-cell linker

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BLNK mRNA

NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113

G

biliverdin reductase B

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

G

basic helix-loop-helix ARNT like 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of BMAL1 mRNA
beta-Naphthoflavone results in increased expression of BMAL1 mRNA
beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to BMAL1 protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to BMAL1 protein]; BMAL1 affects the reaction [beta-Naphthoflavone results in increased expression of PPARA mRNA]

PMID:18164116 PMID:20106950 PMID:21849270 PMID:32151702

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

G

BCL2 family apoptosis regulator BOK

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BOK mRNA

NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476

G

bisphosphoglycerate mutase

decreases expression

beta-Naphthoflavone results in decreased expression of BPGM mRNA

NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581

G

BMP/retinoic acid inducible neural specific 1

increases expression

beta-Naphthoflavone results in increased expression of BRINP1 mRNA

NCBI chr 5:82,348,501...82,550,506
Ensembl chr 5:82,348,930...82,493,150

G

B-box and SPRY domain containing

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BSPRY mRNA

NCBI chr 5:75,927,397...75,949,585
Ensembl chr 5:75,927,405...75,949,583

G

BTG anti-proliferation factor 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BTG3 mRNA

NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170

G

C1q and TNF related 1

decreases expression

beta-Naphthoflavone results in decreased expression of C1QTNF1 mRNA

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

G

C1q and TNF related 6

decreases expression

beta-Naphthoflavone results in decreased expression of C1QTNF6 mRNA

NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412

G

similar to human chromosome 11 open reading frame 96

decreases expression

beta-Naphthoflavone results in decreased expression of C11ORF96 mRNA

NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523

G

similar to human chromosome 2 open reading frame 88

decreases expression

beta-Naphthoflavone results in decreased expression of C2ORF88 mRNA

NCBI chr 9:48,539,140...48,584,882
Ensembl chr 9:48,568,409...48,584,831

G

calcium binding protein 39-like

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CAB39L mRNA

NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545

G

calcium voltage-gated channel auxiliary subunit alpha2delta 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CACNA2D1 mRNA

NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969

G

calcium voltage-gated channel auxiliary subunit gamma 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CACNG5 mRNA

NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614

G

calpain 6

decreases expression

beta-Naphthoflavone results in decreased expression of CAPN6 mRNA

NCBI chr X:107,380,774...107,405,489
Ensembl chr X:107,380,774...107,405,489

G

calcyphosine

decreases expression

beta-Naphthoflavone results in decreased expression of CAPS mRNA

NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647

G

carbonic anhydrase 11

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CAR11 mRNA

NCBI chr 1:96,169,900...96,175,191
Ensembl chr 1:96,170,080...96,175,191

G

carbonic anhydrase 2

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CA2 mRNA
beta-Naphthoflavone results in decreased expression of CA2 mRNA

PMID:18164116 PMID:32858204

NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818

G

carbonic anhydrase 3

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CA3 mRNA
beta-Naphthoflavone results in decreased expression of CAR3 mRNA

PMID:18164116 PMID:23994337

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

caspase 1

decreases expression

beta-Naphthoflavone results in decreased expression of CASP1 mRNA

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 3

multiple interactions

beta-Naphthoflavone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caveolin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CAV mRNA

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

Cbl proto-oncogene C

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CBLC mRNA

NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755

G

carbonyl reductase 1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of CBR1 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CBR1 mRNA

PMID:17569794 PMID:19737545 PMID:19737606

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

carbonyl reductase 3

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

coiled-coil domain containing 80

decreases expression

beta-Naphthoflavone results in decreased expression of CCDC80 mRNA

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

coiled-coil domain containing 85B

increases expression

beta-Naphthoflavone results in increased expression of CCDC85B mRNA

NCBI chr 1:202,763,645...202,764,660
Ensembl chr 1:202,763,631...202,764,703

G

cholecystokinin

decreases expression

beta-Naphthoflavone results in decreased expression of CCK mRNA

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

cholecystokinin B receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCKBR mRNA

NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881

G

C-C motif chemokine ligand 2

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA]
beta-Naphthoflavone results in increased expression of CCL2 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CCL2 mRNA

PMID:19737545 PMID:21295105 PMID:22687991

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

decreases expression

beta-Naphthoflavone results in decreased expression of CCL20 mRNA

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 22

decreases expression

beta-Naphthoflavone results in decreased expression of CCL22 mRNA

NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400

G

C-C motif chemokine ligand 3

decreases expression

beta-Naphthoflavone results in decreased expression of CCL3 mRNA

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 5

decreases expression

beta-Naphthoflavone results in decreased expression of CCL5 mRNA

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 9

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CCL6 mRNA

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

G

cellular communication network factor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cellular communication network factor 2

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CCN2 mRNA
beta-Naphthoflavone results in decreased expression of CCN2 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN2 mRNA

PMID:18164116 PMID:19737545 PMID:19737606 PMID:32151702

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN5 mRNA

NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636

G

cyclin A1

decreases expression

beta-Naphthoflavone results in decreased expression of CCNA1 mRNA

NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157

G

cyclin A2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin B2

decreases expression

beta-Naphthoflavone results in decreased expression of CCNB2 mRNA

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

cyclin D1

decreases expression

beta-Naphthoflavone results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

chaperonin containing TCP1 subunit 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCT3 mRNA

NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757

G

CD24 molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD24 mRNA

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

G

Cd276 molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD276 mRNA

NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380

G

Cd300 molecule-like family member F

decreases expression

beta-Naphthoflavone results in decreased expression of CD300LF mRNA

NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041

G

CD36 molecule

increases expression

beta-Naphthoflavone results in increased expression of CD36 mRNA

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

G

CD38 molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD38 mRNA

NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986

G

Cd47 molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CD47 mRNA

NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425

G

Cd48 molecule

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD48 mRNA
beta-Naphthoflavone results in decreased expression of CD48 mRNA

PMID:18164116 PMID:32858204

NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142

G

CD52 molecule

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD52 mRNA
beta-Naphthoflavone results in decreased expression of CD52 mRNA

PMID:18164116 PMID:32858204

NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348

G

Cd63 molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD63 mRNA

NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178

G

CD86 molecule

decreases expression

beta-Naphthoflavone results in decreased expression of CD86 mRNA

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

G

CD9 molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD9 mRNA

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

G

cell division cycle 20

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDC20 mRNA
beta-Naphthoflavone results in decreased expression of CDC20 mRNA

PMID:18164116 PMID:21295105 PMID:32858204

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

CDC42 binding protein kinase alpha

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDC42BPA mRNA

NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732

G

CDC42 effector protein 2

increases expression

beta-Naphthoflavone results in increased expression of CDC42EP2 mRNA

NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897

G

cell division cycle associated 5

affects expression

beta-Naphthoflavone affects the expression of CDCA5 mRNA

NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023

G

cell division cycle associated 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDCA8 mRNA

NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629

G

cadherin 11

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH11 mRNA

NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272

G

cadherin 13

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH13 mRNA

NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459

G

cadherin 17

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDH17 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CDH17 mRNA

PMID:18164116 PMID:19737545

NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884

G

cadherin 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH3 mRNA

NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084

G

cadherin-related family member 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDHR5 mRNA

NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543

G

cyclin-dependent kinase 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDK1 mRNA
beta-Naphthoflavone results in decreased expression of CDK1 mRNA

PMID:18164116 PMID:32858204

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 13

increases expression

beta-Naphthoflavone results in increased expression of CDK13 mRNA

NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721

G

CDK5 regulatory subunit associated protein 2

increases expression

beta-Naphthoflavone results in increased expression of CDK5RAP2 mRNA

NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782

G

cyclin-dependent kinase inhibitor 1A

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CDKN1A mRNA; beta-Naphthoflavone results in decreased expression of CDKN1A protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDKN1A mRNA

PMID:18164116 PMID:19389873 PMID:22687991

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1C

decreases expression

beta-Naphthoflavone results in decreased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2B

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of CDKN2B mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA]

PMID:21295105 PMID:22687991

NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050

G

cysteine dioxygenase type 1

decreases expression

beta-Naphthoflavone results in decreased expression of CDO1 mRNA

NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296

G

cerebellar degeneration-related protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDR2 mRNA

NCBI chr 1:175,502,837...175,527,746
Ensembl chr 1:175,502,838...175,537,472

G

caudal type homeo box 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDX2 mRNA

NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142

G

CEA cell adhesion molecule 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CEACAM1 mRNA

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

CCAAT/enhancer binding protein alpha

decreases expression

beta-Naphthoflavone results in decreased expression of CEBPA mRNA; beta-Naphthoflavone results in decreased expression of CEBPA protein

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

chymotrypsin like elastase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CELA1 mRNA

NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285

G

cadherin, EGF LAG seven-pass G-type receptor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CELSR1 mRNA

NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164

G

centromere protein I

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CENPI mRNA

NCBI chr X:97,515,919...97,567,671
Ensembl chr X:97,515,972...97,567,657

G

centromere protein X

increases expression

beta-Naphthoflavone results in increased expression of CENPX mRNA

NCBI chr10:105,991,469...105,994,310

G

carboxylesterase 1D

increases expression

beta-Naphthoflavone results in increased expression of CES1 mRNA

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

carboxylesterase 2E

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CES2E mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CES2E mRNA]
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CES2E mRNA

PMID:18164116 PMID:22234961

NCBI chr19:157,447...172,822
Ensembl chr19:157,407...172,856

G

carboxylesterase 3a

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CES3 mRNA; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CES3 mRNA]

PMID:19737545 PMID:22234961

NCBI chr19:32,992,386...33,000,562

G

cilia and flagella associated protein 45

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CFAP45 mRNA

NCBI chr13:84,989,474...85,012,880
Ensembl chr13:84,981,728...85,012,878

G

craniofacial development protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CFDP1 mRNA

NCBI chr19:39,718,313...39,823,824
Ensembl chr19:39,718,347...39,823,824

G

cholesterol 25-hydroxylase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CH25H mRNA

NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195

G

coiled-coil-helix-coiled-coil-helix domain containing 6

decreases expression

beta-Naphthoflavone results in decreased expression of CHCHD6 mRNA

NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216

G

choline dehydrogenase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHDH mRNA

NCBI chr16:5,194,269...5,225,541
Ensembl chr16:5,194,269...5,225,537

G

chondroitin polymerizing factor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHPF mRNA

NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878

G

cholinergic receptor nicotinic beta 1 subunit

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHRNB1 mRNA

NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345

G

chondroitin sulfate synthase 1

decreases expression

beta-Naphthoflavone results in decreased expression of CHSY1 mRNA

NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601

G

cytokine inducible SH2-containing protein

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CISH mRNA

NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

CDC28 protein kinase regulatory subunit 1B

decreases expression

beta-Naphthoflavone results in decreased expression of CKS1B mRNA

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

chloride voltage-gated channel 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLCN5 mRNA

NCBI chr X:15,185,380...15,339,977
Ensembl chr X:15,185,451...15,334,264

G

claudin 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLDN1 mRNA
beta-Naphthoflavone results in increased expression of CLDN1 mRNA

PMID:18164116 PMID:32151702

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 4

increases expression

beta-Naphthoflavone results in increased expression of CLDN4 mRNA

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

claudin 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CLDN7 mRNA

NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171

G

C-type lectin domain family 12, member A

decreases expression

beta-Naphthoflavone results in decreased expression of CLEC12A mRNA

NCBI chr 4:162,798,125...162,816,757
Ensembl chr 4:162,798,125...162,816,753

G

C-type lectin domain family 1, member A

decreases expression

beta-Naphthoflavone results in decreased expression of CLEC1A mRNA

NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247

G

chloride intracellular channel 1

increases expression

beta-Naphthoflavone results in increased expression of CLIC1 mRNA

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

clock circadian regulator

multiple interactions

beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to BMAL1 protein]; beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to PER1 promoter]

NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400

G

caseinolytic mitochondrial matrix peptidase chaperone subunit X

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLPX mRNA

NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082

G

citramalyl-CoA lyase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLYBL mRNA

NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695

G

cornifelin

increases expression

beta-Naphthoflavone results in increased expression of CNFN mRNA

NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747

G

calponin 2

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CNN2 mRNA

NCBI chr 7:9,712,505...9,719,678
Ensembl chr 7:9,712,516...9,719,656

G

calponin 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CNN3 mRNA

NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104

G

2',3'-cyclic nucleotide 3' phosphodiesterase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CNP1 mRNA

NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720

G

collagen type XVI alpha 1 chain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL16A1 mRNA

NCBI chr 5:142,388,376...142,442,825
Ensembl chr 5:142,388,426...142,442,825

G

collagen type XVII alpha 1 chain

decreases expression

beta-Naphthoflavone results in decreased expression of COL17A1 mRNA

NCBI chr 1:246,530,589...246,577,559
Ensembl chr 1:246,531,367...246,577,632

G

collagen type XVIII alpha 1 chain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL18A1 mRNA

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

collagen type I alpha 1 chain

multiple interactions
affects expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL1A1 mRNA
beta-Naphthoflavone affects the expression of COL1A1 mRNA

PMID:18164116 PMID:20045035 PMID:21295105 PMID:23994337

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type XXII alpha 1 chain

decreases expression

beta-Naphthoflavone results in decreased expression of COL22A1 mRNA

NCBI chr 7:103,730,939...103,968,452
Ensembl chr 7:103,731,037...103,968,462

G

collagen type XXVII alpha 1 chain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL27A1 mRNA

NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174

G

collagen type IV alpha 1 chain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL4A1 mRNA

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen type V alpha 1 chain

decreases expression

beta-Naphthoflavone results in decreased expression of COL5A1 mRNA

NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588

G

collagen type VI alpha 2 chain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collectin sub-family member 12

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of COLEC12 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COLEC12 mRNA

PMID:18164116 PMID:19737606

NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618

G

coenzyme Q10B

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of COQ10B mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of COQ10B mRNA]

NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663

G

coenzyme Q8A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of COQ8A mRNA

NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431

G

cytochrome c oxidase subunit 6B2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COX6B2 mRNA

NCBI chr 1:69,094,009...69,095,312

G

carboxypeptidase E

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CPE mRNA

NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233

G

coproporphyrinogen oxidase

increases expression

beta-Naphthoflavone results in increased expression of CPOX mRNA

NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746

G

carboxypeptidase Z

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CPZ mRNA

NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945

G

CRACD like

decreases expression

beta-Naphthoflavone results in decreased expression of CRACDL mRNA

NCBI chr 9:39,834,321...39,950,763
Ensembl chr 9:39,834,833...39,951,086

G

carnitine O-acetyltransferase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CRAT mRNA

NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255

G

cysteine-rich C-terminal 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CRCT1 mRNA

NCBI chr 2:178,633,789...178,635,274
Ensembl chr 2:178,634,092...178,634,394

G

cAMP responsive element binding protein 1

increases expression

beta-Naphthoflavone results in increased expression of CREB1 mRNA

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cAMP responsive element binding protein 5

decreases expression

beta-Naphthoflavone results in decreased expression of CREB5 mRNA

NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325

G

cAMP responsive element modulator

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of CREM mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CREM mRNA

PMID:18164116 PMID:19737606

NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989

G

corticotropin releasing hormone

decreases expression

beta-Naphthoflavone results in decreased expression of CRH mRNA

NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919

G

cysteine-rich protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of CRIP2 mRNA

NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065

G

cysteine-rich secretory protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CRISP2 mRNA

NCBI chr 9:20,107,649...20,131,967
Ensembl chr 9:20,107,701...20,131,959

G

carnitine O-octanoyltransferase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CROT mRNA

NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109

G

crystallin, alpha B

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CRYAB mRNA
beta-Naphthoflavone results in decreased expression of CRYAB mRNA

PMID:18164116 PMID:32858204

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

crystallin zeta

multiple interactions
increases activity
increases expression

AHR protein promotes the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Copper inhibits the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]; Lead inhibits the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]; Mercury promotes the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]

NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758

G

colony stimulating factor 1 receptor

decreases expression

beta-Naphthoflavone results in decreased expression of CSF1R mRNA

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

colony stimulating factor 3 receptor

decreases expression

beta-Naphthoflavone results in decreased expression of CSF3R mRNA

NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881

G

CUB and Sushi multiple domains 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CSMD1 mRNA

NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614

G

casein beta

multiple interactions
decreases expression

AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of CSN2 mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of CSN2 mRNA]
beta-Naphthoflavone results in decreased expression of CSN2 mRNA; beta-Naphthoflavone results in decreased expression of CSN2 protein

NCBI chr14:20,322,581...20,329,818
Ensembl chr14:20,322,581...20,329,817

G

cysteine and glycine-rich protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of CSRP2 mRNA

NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745

G

catenin beta 1

multiple interactions

CTNNB1 gene mutant form affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; CTNNB1 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

cathepsin C

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CTSC mRNA

NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387

G

cullin 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CUL5 mRNA

NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666

G

C-X3-C motif chemokine ligand 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CX3CL1 mRNA

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

G

C-X-C motif chemokine ligand 1

increases expression

beta-Naphthoflavone results in increased expression of CXCL1 mRNA

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 10

decreases expression

beta-Naphthoflavone results in decreased expression of CXCL10 mRNA

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 11

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CXCL11 mRNA
beta-Naphthoflavone results in increased expression of CXCL11 mRNA

PMID:18164116 PMID:32151702

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

G

C-X-C motif chemokine ligand 12

decreases expression

beta-Naphthoflavone results in decreased expression of CXCL12 mRNA

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 13

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CXCL13 mRNA

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

G

C-X-C motif chemokine ligand 16

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CXCL16 mRNA

NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592

G

C-X-C motif chemokine ligand 2

increases expression

beta-Naphthoflavone results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

increases expression

beta-Naphthoflavone results in increased expression of CXCL1 mRNA

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 6

multiple interactions
increases expression

IL1B protein promotes the reaction [beta-Naphthoflavone results in increased expression of CXCL5 mRNA]

NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093

G

C-X-C motif chemokine receptor 6

decreases expression

beta-Naphthoflavone results in decreased expression of CXCR6 mRNA

NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526

G

cytochrome b5 type B

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CYB5B mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYB5B mRNA]

NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249

G

cytochrome b5 reductase 2

increases expression

beta-Naphthoflavone results in increased expression of CYB5R2 mRNA

NCBI chr 1:161,655,862...161,664,359
Ensembl chr 1:161,655,864...161,664,097

G

cytoplasmic FMR1 interacting protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of CYFIP2 mRNA

NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113

G

cytoglobin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYGB mRNA

NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442

G

cytochrome P450, family 11, subfamily a, polypeptide 1

decreases expression

beta-Naphthoflavone results in decreased expression of CYP11A1 mRNA

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 11, subfamily b, polypeptide 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of CYP11B1 mRNA
beta-Naphthoflavone promotes the reaction [CYP11B1 protein results in increased chemical synthesis of Hydrocortisone]

NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004

G

cytochrome P450, family 17, subfamily a, polypeptide 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of CYP19A1 mRNA
beta-Naphthoflavone results in decreased expression of CYP19A1 mRNA

PMID:19737606 PMID:32858204

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases activity
increases activity
increases expression
multiple interactions

beta-Naphthoflavone results in decreased activity of CYP1A1 protein
beta-Naphthoflavone results in increased activity of CYP1A1 promoter; beta-Naphthoflavone results in increased activity of CYP1A1 protein
beta-Naphthoflavone results in increased expression of CYP1A1; beta-Naphthoflavone results in increased expression of CYP1A1 mRNA; beta-Naphthoflavone results in increased expression of CYP1A1 protein
3'-methoxy-4'-nitroflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; beta-Naphthoflavone promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Resveratrol results in increased expression of CYP1A1 protein]; beta-Naphthoflavone results in increased expression of and results in increased activity of CYP1A1 protein; CYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 mRNA]]; CYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; CYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]]; Resveratrol inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Sorafenib inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Sorafenib inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 mRNA; [beta-Naphthoflavone binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [beta-Naphthoflavone binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [beta-Naphthoflavone results in increased expression of CYP1A2 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; [beta-Naphthoflavone results in increased expression of NQO1 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; Acetylcysteine affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Acetylcysteine affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [beta-Naphthoflavone results in decreased activity of CYP1A1 protein]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; andrographolide promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Apigenin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Apigenin promotes the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; ARNT affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Arsenic inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Arsenic promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Ascorbic Acid affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Ascorbic Acid affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Berberine inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; beta-Naphthoflavone promotes the reaction [14-deoxy-11,12-didehydroandrographolide results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [andrographolide results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased activity of CYP1A1 protein]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 protein]; Buthionine Sulfoximine promotes the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Buthionine Sulfoximine promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Butylated Hydroxytoluene affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Cadmium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Cadmium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Cadmium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Chromium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Chromium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; chrysin promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Copper inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; CTNNB1 gene mutant form affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; CYP1A1 protein affects the reaction [beta-Naphthoflavone results in increased metabolism of Imiquimod]; Dactinomycin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; FH535 inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; flavanone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; galangin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Glutathione affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Glutathione affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Hydrogen Peroxide promotes the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Hydrogen Peroxide promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Lead inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Lead inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Lipopolysaccharides inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Luteolin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; morin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; myricetin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; naringenin promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; neoandrographolide inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Oxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Oxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Quercetin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Sorafenib inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Sorafenib inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 protein; [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 protein; AHR protein promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Amiodarone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Diethylnitrosamine results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone results in increased expression of and results in increased activity of CYP1A1 protein; Curcumin inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; diphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Drugs, Chinese Herbal inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Genistein inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Quercetin inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Resveratrol inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Silymarin inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Tamoxifen inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]

PMID:1358564 PMID:2154339 PMID:3379039 PMID:3929785 PMID:7646562 More...

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

decreases activity
increases activity
multiple interactions
increases expression
increases response to substance

beta-Naphthoflavone results in decreased activity of CYP1A2 protein
beta-Naphthoflavone results in increased activity of CYP1A2 protein
beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; beta-Naphthoflavone promotes the reaction [CYP1A2 protein affects the metabolism of Thiabendazole]; CYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 mRNA]]; CYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; CYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]]; CYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 protein]]; CYP1A2 gene mutant form promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]
[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 protein; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; beta-Naphthoflavone results in increased expression of and results in increased activity of CYP1A2 protein; diphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A2 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]
beta-Naphthoflavone results in increased expression of CYP1A2 mRNA; beta-Naphthoflavone results in increased expression of CYP1A2 protein
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA; [beta-Naphthoflavone results in increased expression of CYP1A2 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; [beta-Naphthoflavone results in increased expression of CYP1A2 protein] which results in decreased susceptibility to Oxygen; [furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [beta-Naphthoflavone results in increased activity of AHR protein]; Berberine inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased activity of CYP1A2 protein]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A2 mRNA]; CTNNB1 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]; CYP1A2 protein affects the reaction [beta-Naphthoflavone results in increased metabolism of Imiquimod]; Oxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]
CYP1A2 gene mutant form results in increased susceptibility to beta-Naphthoflavone

PMID:2208584 PMID:3038308 PMID:8419313 PMID:8902619 PMID:10463385 More...

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions
increases expression

beta-Naphthoflavone binds to and results in decreased activity of CYP1B1 protein
andrographolide promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]; Apigenin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]
beta-Naphthoflavone results in increased expression of CYP1B1 mRNA; beta-Naphthoflavone results in increased expression of CYP1B1 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1B1 mRNA
beta-Naphthoflavone results in increased expression of CYP1B1; beta-Naphthoflavone results in increased expression of CYP1B1 mRNA

PMID:12623754 PMID:14990334 PMID:16985168 PMID:18164116 PMID:19389873 More...

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 26, subfamily a, polypeptide 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP26A1 mRNA

NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 27, subfamily b, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP27B1 mRNA

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

G

cytochrome P450, family 2, subfamily a, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP2A1 mRNA
beta-Naphthoflavone results in increased expression of CYP2A13 mRNA

PMID:19118567 PMID:22258563

NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887

G

cytochrome P450, family 2, subfamily a, polypeptide 3

multiple interactions

beta-Naphthoflavone promotes the reaction [andrographolide results in increased expression of CYP2A4 mRNA]

NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979

G

cytochrome P450, family 2, subfamily b, polypeptide 1

increases activity
increases expression
multiple interactions

beta-Naphthoflavone results in increased activity of CYP2B1 protein
beta-Naphthoflavone results in increased expression of CYP2B1 mRNA; beta-Naphthoflavone results in increased expression of CYP2B1 protein
beta-Naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP2B1 protein]

PMID:15588932 PMID:15607757 PMID:16054776

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 2

multiple interactions
decreases expression
increases activity

beta-Naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP2B2 protein]
beta-Naphthoflavone results in decreased expression of CYP2B2 mRNA
beta-Naphthoflavone results in increased activity of CYP2B2 protein

PMID:16054776 PMID:20607812

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression
increases activity
multiple interactions

beta-Naphthoflavone results in increased expression of CYP2B6 mRNA
beta-Naphthoflavone results in increased activity of CYP2B6 protein
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP2B10 mRNA

PMID:19118567 PMID:19497361 PMID:19737545 PMID:22258563

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, subfamily 2, polypeptide 11

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C11 protein
beta-Naphthoflavone results in decreased expression of CYP2C18 mRNA

PMID:16985168 PMID:18164116 PMID:30842367

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CYP2C19 mRNA
[Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP2C6V1 protein

PMID:16985168 PMID:30842367 PMID:33263786

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily c, polypeptide 7

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CYP2C7 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C7 mRNA

PMID:18164116 PMID:20607812

NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases expression

beta-Naphthoflavone results in decreased expression of CYP2D6 mRNA

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression
decreases expression
multiple interactions

beta-Naphthoflavone results in increased expression of CYP2E1 mRNA
beta-Naphthoflavone results in decreased expression of CYP2E1 mRNA
[Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2E1 protein
beta-Naphthoflavone results in increased expression of CYP2E1 mRNA; beta-Naphthoflavone results in increased expression of CYP2E1 protein
[CYP2E1 protein co-treated with beta-Naphthoflavone] results in increased expression of KLF6 protein

PMID:19969063 PMID:22258563 PMID:22486562 PMID:30373287 PMID:30842367

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 2, subfamily j, polypeptide 3

increases expression

beta-Naphthoflavone results in increased expression of CYP2J3 mRNA

NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 2, subfamily j, polypeptide 4

decreases expression

beta-Naphthoflavone results in decreased expression of CYP2J2 mRNA

NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 2, subfamily s, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP2S1 mRNA

NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303

G

cytochrome P450, family 2, subfamily u, polypeptide 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2U1 mRNA

NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882

G

cytochrome P450, family 2, subfamily w, polypeptide 1

decreases expression

beta-Naphthoflavone results in decreased expression of CYP2W1 mRNA

NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
increases activity
affects binding
decreases expression
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP3A2 mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP3A2 protein; diphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP3A2 protein]
beta-Naphthoflavone binds to CYP3A4 protein
[[beta-Naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam] which results in increased chemical synthesis of 1-hydroxymethylmidazolam; [beta-Naphthoflavone results in increased activity of CYP3A4 protein] which results in increased metabolism of Midazolam
beta-Naphthoflavone results in decreased expression of CYP3A4 mRNA
beta-Naphthoflavone results in increased expression of CYP3A4 mRNA

PMID:16837568 PMID:16985168 PMID:18164116 PMID:21053930 PMID:22258563 More...

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

decreases expression
increases activity
multiple interactions

beta-Naphthoflavone results in decreased expression of CYP3A23-3A1 mRNA
beta-Naphthoflavone results in increased activity of CYP3A23-3A1 protein
[Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP3A23-3A1 protein; diphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP3A23-3A1 protein]

PMID:19041297 PMID:26880746 PMID:30842367

NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

G

cytochrome P450, family 3, subfamily a, polypeptide 62

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP3A62 mRNA

NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP3A13 mRNA
beta-Naphthoflavone results in decreased expression of CYP3A5 mRNA

PMID:18164116 PMID:33263786

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 4, subfamily a, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP4A1 mRNA

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

cytochrome P450, family 4, subfamily a, polypeptide 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP4A8 mRNA

NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476

G

cytochrome P450, family 4, subfamily b, polypeptide 1

decreases expression

beta-Naphthoflavone results in decreased expression of CYP4B1 mRNA

PMID:16985168 PMID:22258563

NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348

G

cytochrome P450, family 4, subfamily f, polypeptide 18

increases expression

beta-Naphthoflavone results in increased expression of CYP4F3 mRNA

NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940

G

cytochrome P450, family 4, subfamily f, polypeptide 4

increases expression

beta-Naphthoflavone results in increased expression of CYP4F4 mRNA

NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506

G

cytochrome P450, family 51

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP51 mRNA
beta-Naphthoflavone results in decreased expression of CYP51 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYP51 mRNA]

PMID:18164116 PMID:22234961

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410

G

cytochrome P450 family 7 subfamily A member 1

decreases expression

beta-Naphthoflavone results in decreased expression of CYP7A1 mRNA

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 7 subfamily B member 1

increases expression

beta-Naphthoflavone results in increased expression of CYP7B1 mRNA

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

G

drebrin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DBN1 mRNA

NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984

G

D-box binding PAR bZIP transcription factor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

doublecortin-like kinase 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DCLK1 mRNA
beta-Naphthoflavone results in increased expression of DCLK1 mRNA

PMID:18164116 PMID:23994337

NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956

G

decorin

decreases expression

beta-Naphthoflavone results in decreased expression of DCN mRNA

NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270

G

defective in cullin neddylation 1 domain containing 1

increases expression

beta-Naphthoflavone results in increased expression of DCUN1D1 mRNA

NCBI chr 2:118,721,275...118,772,606
Ensembl chr 2:118,721,822...118,772,602

G

dopa decarboxylase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DNA-damage-inducible transcript 4

increases expression

beta-Naphthoflavone results in increased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

defensin beta 1

decreases expression

beta-Naphthoflavone results in decreased expression of DEFB1 mRNA

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

G

defensin beta 14

increases expression

beta-Naphthoflavone results in increased expression of DEFB103A mRNA

NCBI chr16:70,663,443...70,668,473
Ensembl chr16:70,663,333...70,666,540

G

DENN domain containing 2A

decreases expression

beta-Naphthoflavone results in decreased expression of DENND2A mRNA

NCBI chr 4:68,233,016...68,332,235
Ensembl chr 4:68,233,958...68,332,105

G

DEP domain containing 1B

decreases expression

beta-Naphthoflavone results in decreased expression of DEPDC1B mRNA

NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779

G

DEPP autophagy regulator 1

increases expression

beta-Naphthoflavone results in increased expression of DEPP1 mRNA

NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542

G

Dexi homolog

decreases expression

beta-Naphthoflavone results in decreased expression of DEXI mRNA

NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738

G

diacylglycerol O-acyltransferase 2

decreases expression

beta-Naphthoflavone results in decreased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

7-dehydrocholesterol reductase

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of DHCR7 mRNA]

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

dehydrogenase/reductase 9

decreases expression

beta-Naphthoflavone results in decreased expression of DHRS9 mRNA

NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241

G

iodothyronine deiodinase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DIO2 mRNA

NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809

G

dickkopf WNT signaling pathway inhibitor 1

decreases expression

beta-Naphthoflavone results in decreased expression of DKK1 mRNA

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

deleted in malignant brain tumors 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DMBT1 mRNA

NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478

G

dimethylglycine dehydrogenase

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of DMGDH mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of DMGDH mRNA]

NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528

G

dynein, axonemal, heavy chain 9

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DNAH9 mRNA

NCBI chr10:50,496,174...50,864,909
Ensembl chr10:50,497,688...50,864,949

G

DnaJ heat shock protein family (Hsp40) member B11

increases expression

beta-Naphthoflavone results in increased expression of DNAJB11 mRNA

NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407

G

dynamin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DNM1 mRNA

NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538

G

dynamin 1-like

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DNM1L mRNA

NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482

G

DNA methyltransferase 1

decreases expression

beta-Naphthoflavone results in decreased expression of DNMT1 mRNA

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

dedicator of cytokinesis 9

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DOCK9 mRNA

NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153

G

dipeptidase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DPEP1 mRNA

NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257

G

dipeptidylpeptidase 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DPP7 mRNA

NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355

G

dystrobrevin, beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DTNB mRNA

NCBI chr 6:26,566,418...26,763,467
Ensembl chr 6:26,566,925...26,766,335

G

dual specificity phosphatase 13B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DUSP13B mRNA

NCBI chr15:2,567,432...2,575,105
Ensembl chr15:2,533,547...2,575,539

G

dual specificity phosphatase 6

increases expression

beta-Naphthoflavone results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

decapping exoribonuclease

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DXO mRNA

NCBI chr20:3,993,322...3,995,484
Ensembl chr20:3,993,327...3,995,494

G

dynein cytoplasmic 1 heavy chain 1

increases expression

beta-Naphthoflavone results in increased expression of DYNC1H1 mRNA

NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883

G

dysferlin

increases expression

beta-Naphthoflavone results in increased expression of DYSF mRNA

NCBI chr 4:116,490,877...116,690,709
Ensembl chr 4:116,490,616...116,690,709

G

DAZ interacting zinc finger protein 1-like

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DZIP1L mRNA

NCBI chr 8:100,188,414...100,229,077
Ensembl chr 8:100,194,999...100,228,988

G

Epstein-Barr virus induced 3

decreases expression

beta-Naphthoflavone results in decreased expression of EBI3 mRNA

NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544

G

EGF containing fibulin extracellular matrix protein 1

decreases expression

beta-Naphthoflavone results in decreased expression of EFEMP1 mRNA

NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018

G

EGF containing fibulin extracellular matrix protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EFEMP2 mRNA

NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414

G

EF-hand domain family, member D1

decreases expression

beta-Naphthoflavone results in decreased expression of EFHD1 mRNA

NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917

G

egl-9 family hypoxia-inducible factor 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EGLN3 mRNA

NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766

G

early growth response 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

EH-domain containing 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EHD2 mRNA

NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783

G

EH-domain containing 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EHD4 mRNA

NCBI chr 3:107,058,191...107,121,985
Ensembl chr 3:107,058,958...107,122,002

G

EP300 interacting inhibitor of differentiation 3

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of EID3 mRNA
beta-Naphthoflavone results in increased expression of EID3 mRNA

PMID:19737545 PMID:32858204

NCBI chr 7:20,860,073...20,861,395

G

elastin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ELN mRNA

NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928

G

ELOVL fatty acid elongase 3

decreases expression

beta-Naphthoflavone results in decreased expression of ELOVL3 mRNA

NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115

G

ELOVL fatty acid elongase 6

decreases expression

beta-Naphthoflavone results in decreased expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

elastin microfibril interfacer 1

increases expression

beta-Naphthoflavone results in increased expression of EMILIN1 mRNA

NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698

G

epithelial membrane protein 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EMP1 mRNA
beta-Naphthoflavone results in decreased expression of EMP1 mRNA

PMID:18164116 PMID:32858204

NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904

G

epithelial membrane protein 3

increases expression

beta-Naphthoflavone results in increased expression of EMP3 mRNA

NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988

G

empty spiracles homeobox 2

decreases expression

beta-Naphthoflavone results in decreased expression of EMX2 mRNA

NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594

G

ectodermal-neural cortex 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENC1 mRNA

NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713

G

ectonucleotide pyrophosphatase/phosphodiesterase family member 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENPP5 mRNA

NCBI chr 9:16,910,187...16,917,633
Ensembl chr 9:16,910,831...16,917,480

G

ectonucleoside triphosphate diphosphohydrolase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENTPD2 mRNA

NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866

G

epithelial cell adhesion molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EPCAM mRNA

NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127

G

ependymin related 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EPDR1 mRNA

NCBI chr17:45,333,932...45,358,597
Ensembl chr17:45,333,956...45,358,594

G

epoxide hydrolase 1

decreases activity
increases expression

beta-Naphthoflavone results in decreased activity of EPHX1 protein
beta-Naphthoflavone results in increased expression of EPHX1 mRNA

PMID:3621371 PMID:22258563 PMID:23994337

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

elongin BC and polycomb repressive complex 2 associated protein

increases expression

beta-Naphthoflavone results in increased expression of EPOP mRNA

NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912

G

epidermal growth factor receptor pathway substrate 15

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of EPS15 mRNA

NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221

G

erb-b2 receptor tyrosine kinase 2

decreases expression

beta-Naphthoflavone results in decreased expression of ERBB2 mRNA

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

endothelial cell adhesion molecule

decreases expression

beta-Naphthoflavone results in decreased expression of ESAM mRNA

NCBI chr 8:37,238,228...37,249,217
Ensembl chr 8:37,238,287...37,249,215

G

endothelial cell-specific molecule 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ESM1 mRNA

NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804

G

estrogen receptor 1

multiple interactions
affects binding
decreases expression

[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR1 mRNA
[beta-Naphthoflavone binds to AHR protein] which binds to ESR1 protein
beta-Naphthoflavone results in decreased expression of ESR1 mRNA

PMID:10620335 PMID:20607812 PMID:22975028

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions

[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR2 mRNA

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

estrogen related receptor, alpha

affects binding

[beta-Naphthoflavone binds to AHR protein] which binds to ESRRA protein

NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268

G

ETS variant transcription factor 5

decreases expression

beta-Naphthoflavone results in decreased expression of ETV5 mRNA

NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215

G

eva-1 homolog A, regulator of programmed cell death

decreases expression

beta-Naphthoflavone results in decreased expression of EVA1A mRNA

NCBI chr 4:114,593,773...114,643,011
Ensembl chr 4:114,593,341...114,643,011

G

ezrin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EZR mRNA

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

G

coagulation factor V

decreases expression

beta-Naphthoflavone results in decreased expression of F5 mRNA

NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317

G

fatty acid binding protein 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid desaturase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FADS1 mRNA

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

family with sequence similarity 43, member A

decreases expression

beta-Naphthoflavone results in decreased expression of FAM43A mRNA

NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401

G

fatty acyl CoA reductase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FAR1 mRNA

NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730

G

Fas ligand

multiple interactions

AHR mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [FASLG protein binds to FASLG protein]]; beta-Naphthoflavone results in increased activity of [FASLG protein binds to FASLG protein]

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

fatty acid synthase

decreases expression

beta-Naphthoflavone results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

filamin binding LIM protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FBLIM1 mRNA

NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757

G

fibulin 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FBLN2 mRNA

NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948

G

fibulin 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FBLN5 mRNA

NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755

G

fibrillin 2

decreases expression

beta-Naphthoflavone results in decreased expression of FBN2 mRNA

NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976

G

F-box protein 21

increases expression

beta-Naphthoflavone results in increased expression of FBXO21 mRNA

NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133

G

F-box protein 25

increases expression

beta-Naphthoflavone results in increased expression of FBXO25 mRNA

NCBI chr16:75,666,062...75,701,770
Ensembl chr16:75,667,904...75,701,696

G

farnesyl diphosphate farnesyl transferase 1

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of FDFT1 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FDFT1 mRNA]

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

decreases expression

beta-Naphthoflavone results in decreased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

ferredoxin 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of FDX1 mRNA
beta-Naphthoflavone results in decreased expression of FDX1 mRNA

PMID:18164116 PMID:32858204

NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414

G

fibrinogen beta chain

decreases expression

beta-Naphthoflavone results in decreased expression of FGB mRNA

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

G

FYVE, RhoGEF and PH domain containing 5

increases expression

beta-Naphthoflavone results in increased expression of FGD5 mRNA

NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563

G

fibroblast growth factor 21

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of FGF21 mRNA

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

four and a half LIM domains 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FHL1 mRNA
beta-Naphthoflavone results in decreased expression of FHL1 mRNA

PMID:18164116 PMID:32858204

NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928

G

four and a half LIM domains 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FHL2 mRNA

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

FKBP prolyl isomerase 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FKBP5 mRNA

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

filaggrin

decreases expression

beta-Naphthoflavone results in decreased expression of FLG protein

NCBI chr 2:178,884,793...178,912,986

G

filamin C

increases expression

beta-Naphthoflavone results in increased expression of FLNC mRNA

NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844

G

flavin containing dimethylaniline monoxygenase 1

decreases expression

beta-Naphthoflavone results in decreased expression of FMO1 mRNA

NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647

G

flavin containing dimethylaniline monoxygenase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FMO2 mRNA

NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308

G

flavin containing dimethylaniline monoxygenase 5

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FMO5 mRNA
beta-Naphthoflavone results in decreased expression of FMO5 mRNA

PMID:18164116 PMID:22258563

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

fibronectin type III domain containing 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FNDC1 mRNA

NCBI chr 1:47,281,839...47,364,247
Ensembl chr 1:47,281,844...47,364,259

G

fibronectin type III domain containing 4

increases expression

beta-Naphthoflavone results in increased expression of FNDC4 mRNA

NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FOS mRNA
beta-Naphthoflavone promotes the reaction [FOS protein binds to NQO1 promoter]
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FOS protein]; beta-Naphthoflavone results in decreased expression of and results in increased ubiquitination of FOS protein; UBE2L3 protein affects the reaction [beta-Naphthoflavone results in decreased expression of FOS protein]
beta-Naphthoflavone results in increased expression of FOS mRNA

PMID:8375015 PMID:18164116 PMID:26318284 PMID:32151702

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FosB proto-oncogene, AP-1 transcription factor subunit

increases expression

beta-Naphthoflavone results in increased expression of FOSB mRNA

NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

frizzled-related protein

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FRZB mRNA
beta-Naphthoflavone results in decreased expression of FRZB mRNA

PMID:18164116 PMID:32858204

NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208

G

fascin actin-bundling protein 1

decreases expression

beta-Naphthoflavone results in decreased expression of FSCN1 mRNA

NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211

G

follicle stimulating hormone subunit beta

multiple interactions

beta-Naphthoflavone inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

follistatin-like 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FSTL1 mRNA
beta-Naphthoflavone results in decreased expression of FSTL1 mRNA

PMID:18164116 PMID:32858204

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

G0/G1switch 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphate dehydrogenase

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of G6PD protein
beta-Naphthoflavone results in increased expression of G6PD mRNA

PMID:28903497 PMID:32858204

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

GABA type A receptor associated protein like 1

increases expression

beta-Naphthoflavone results in increased expression of GABARAPL1 mRNA

NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450

G

gamma-aminobutyric acid type A receptor subunit gamma 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GABRG1 mRNA

NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956

G

growth arrest and DNA-damage-inducible, beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GADD45B mRNA

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

polypeptide N-acetylgalactosaminyltransferase 10

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GALNT10 mRNA

NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013

G

polypeptide N-acetylgalactosaminyltransferase 18

decreases expression

beta-Naphthoflavone results in decreased expression of GALNT18 mRNA

NCBI chr 1:165,593,180...165,904,268
Ensembl chr 1:165,593,187...165,904,268

G

galanin receptor 2

increases expression

beta-Naphthoflavone results in increased expression of GALR2 mRNA

NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

beta-Naphthoflavone results in increased expression of GAPDH mRNA

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

growth arrest-specific 1

decreases expression

beta-Naphthoflavone results in decreased expression of GAS1 mRNA

NCBI chr17:4,482,168...4,485,153

G

GATA binding protein 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GATA3 mRNA

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

G

glucosylceramidase beta 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GBA2 mRNA

NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072

G

guanylate binding protein family member 6

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of GBP6 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of GBP6 mRNA]

NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062

G

glucagon receptor

decreases expression

beta-Naphthoflavone results in decreased expression of GCGR mRNA

NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640

G

GTP cyclohydrolase I feedback regulator

decreases expression

beta-Naphthoflavone results in decreased expression of GCHFR mRNA

NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080

G

glucokinase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GCK mRNA

NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995

G

glutamate-cysteine ligase, catalytic subunit

increases expression

beta-Naphthoflavone results in increased expression of GCLC mRNA

PMID:16426233 PMID:23994337

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of GCLM mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GCLM mRNA

PMID:19737545 PMID:19737606 PMID:32858204

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

glial cells missing transcription factor 1

decreases expression

beta-Naphthoflavone results in decreased expression of GCM1 mRNA

NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924

G

glucosaminyl (N-acetyl) transferase 3, mucin type

increases expression

beta-Naphthoflavone results in increased expression of GCNT3 mRNA

NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562

G

growth differentiation factor 11

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GDF11 mRNA

NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725

G

growth differentiation factor 15

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of GDF15 mRNA
beta-Naphthoflavone results in decreased expression of GDF15 mRNA

PMID:19737606 PMID:32858204

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

growth differentiation factor 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GDF6 mRNA

NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567

G

growth factor, augmenter of liver regeneration

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GFER mRNA

NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869

G

growth hormone 1

decreases expression

beta-Naphthoflavone results in decreased expression of GH1 mRNA

NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078

G

gap junction protein, alpha 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GJA5 mRNA

NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952

G

gastrokine 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GKN1 mRNA

NCBI chr 4:119,790,101...119,795,389
Ensembl chr 4:119,790,101...119,795,389

G

galactosidase, alpha

increases expression

beta-Naphthoflavone results in increased expression of GLA mRNA

NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664

G

gliomedin

decreases expression

beta-Naphthoflavone results in decreased expression of GLDN mRNA

NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196

G

glutaminase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GLS2 mRNA

NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426

G

glutamate-ammonia ligase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GLUL mRNA

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

GDP-mannose 4, 6-dehydratase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GMDS mRNA

NCBI chr17:32,095,315...32,621,975
Ensembl chr17:32,095,386...32,621,961

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

decreases expression

beta-Naphthoflavone results in decreased expression of GNE mRNA

NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499

G

G protein subunit gamma 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GNG8 mRNA

NCBI chr 1:77,564,512...77,568,371
Ensembl chr 1:77,564,515...77,568,371

G

glucosamine-6-phosphate deaminase 1

decreases expression

beta-Naphthoflavone results in decreased expression of GNPDA1 mRNA

NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486

G

golgin A3

decreases expression

beta-Naphthoflavone results in decreased expression of GOLGA3 mRNA

NCBI chr12:46,452,409...46,500,509
Ensembl chr12:46,454,870...46,500,509

G

glycerol-3-phosphate acyltransferase, mitochondrial

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPAM mRNA

NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639

G

G protein-coupled bile acid receptor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPBAR1 mRNA

NCBI chr 9:75,860,758...75,863,260
Ensembl chr 9:75,860,677...75,863,168

G

glypican 3

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPC3 mRNA
beta-Naphthoflavone results in decreased expression of GPC3 mRNA

PMID:18164116 PMID:32858204

NCBI chr X:131,868,986...132,236,824
Ensembl chr X:131,868,990...132,236,798

G

glycerol-3-phosphate dehydrogenase 2

decreases expression

beta-Naphthoflavone results in decreased expression of GPD2 mRNA

NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901

G

glycoprotein m6a

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPM6A mRNA

NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475

G

glycoprotein m6b

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPM6B mRNA

NCBI chr X:28,057,788...28,204,409
Ensembl chr X:28,059,450...28,204,211

G

G protein-coupled receptor 35

increases expression

beta-Naphthoflavone results in increased expression of GPR35 mRNA

NCBI chr 9:93,527,165...93,539,573
Ensembl chr 9:93,527,127...93,539,299

G

G protein-coupled receptor 68

increases expression

beta-Naphthoflavone results in increased expression of GPR68 mRNA

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

G

G protein-coupled receptor, class C, group 5, member C

increases expression

beta-Naphthoflavone results in increased expression of GPRC5C mRNA

NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926

G

glutamic--pyruvic transaminase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPT mRNA

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPX1 mRNA

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of GPX2 mRNA; beta-Naphthoflavone results in increased expression of GPX2 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPX2 mRNA

PMID:18164116 PMID:19389873 PMID:20045035 PMID:21203749 PMID:22687991

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPX3 mRNA

NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035

G

glutathione peroxidase 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPX6 mRNA

NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091

G

growth factor receptor bound protein 7

decreases expression

beta-Naphthoflavone results in decreased expression of GRB7 mRNA

NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052

G

glutamate ionotropic receptor AMPA type subunit 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GRIA1 mRNA

NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

increases expression

beta-Naphthoflavone results in increased expression of GRINA mRNA

NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366

G

glutamate metabotropic receptor 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GRM7 mRNA

NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344

G

gasdermin D

increases expression

beta-Naphthoflavone results in increased expression of GSDMD mRNA

NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055

G

glutathione-disulfide reductase

increases expression

beta-Naphthoflavone results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 1

decreases expression
multiple interactions
increases expression

beta-Naphthoflavone results in decreased expression of GSTA1 mRNA
beta-Naphthoflavone promotes the reaction [AHR protein binds to GSTA1 promoter]; beta-Naphthoflavone results in increased expression of and results in increased activity of GSTA1 protein
beta-Naphthoflavone results in increased expression of GSTA1 mRNA

PMID:25218365 PMID:33035518

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

increases expression
increases activity
multiple interactions

beta-Naphthoflavone results in increased expression of GSTA2 mRNA
beta-Naphthoflavone results in increased activity of GSTA2 protein
Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of GSTA2 mRNA]; Copper promotes the reaction [beta-Naphthoflavone results in increased activity of GSTA2 protein]; Lead inhibits the reaction [beta-Naphthoflavone results in increased activity of GSTA2 protein]; Lead inhibits the reaction [beta-Naphthoflavone results in increased expression of GSTA2 mRNA]; Mercury inhibits the reaction [beta-Naphthoflavone results in increased activity of GSTA2 protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of GSTA2 mRNA]
beta-Naphthoflavone results in increased expression of GSTA2 mRNA; beta-Naphthoflavone results in increased expression of GSTA2 protein

PMID:2049074 PMID:12883083 PMID:15297030 PMID:19695238

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 3

increases expression

beta-Naphthoflavone results in increased expression of GSTA3 protein

NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240

G

glutathione S-transferase alpha 4

increases expression

beta-Naphthoflavone results in increased expression of GSTA4 protein

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase alpha 5

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA]
beta-Naphthoflavone results in increased expression of GSTA5 mRNA; beta-Naphthoflavone results in increased expression of GSTA5 protein
Lipopolysaccharides inhibits the reaction [beta-Naphthoflavone results in increased expression of GSTA1 mRNA]
beta-Naphthoflavone results in increased expression of GSTA1 protein

PMID:2049074 PMID:9794803 PMID:15627257 PMID:18164116 PMID:19695238 More...

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of GSTM1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]

PMID:18164116 PMID:18723825 PMID:20045035 PMID:22687991

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of GSTM2 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GSTM2 mRNA

PMID:19695238 PMID:19737545

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase mu 4

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GSTM4 mRNA
beta-Naphthoflavone results in increased expression of GSTM4 mRNA

PMID:19695238 PMID:19737545

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase, mu 5

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GSTM3 mRNA
beta-Naphthoflavone results in increased expression of GSTM3 protein

PMID:9794803 PMID:19737545

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase pi 1

increases expression

beta-Naphthoflavone results in increased expression of GSTP1 mRNA; beta-Naphthoflavone results in increased expression of GSTP1 protein

PMID:9794803 PMID:19118567 PMID:19695238 PMID:23063670

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

guanylate cyclase 2C

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GUCY2C mRNA

NCBI chr 4:169,568,505...169,649,092
Ensembl chr 4:169,568,529...169,649,092

G

glycophorin C

decreases expression

beta-Naphthoflavone results in decreased expression of GYPC mRNA

NCBI chr18:24,160,738...24,193,408
Ensembl chr18:24,160,739...24,193,204

G

H1.2 linker histone, cluster member

increases expression

beta-Naphthoflavone results in increased expression of H1-2 mRNA

NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

increases expression

beta-Naphthoflavone results in increased expression of H6PD mRNA

NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171

G

hydroxyacyl glutathione hydrolase

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of HAGH mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HAGH mRNA]

NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504

G

histidine ammonia lyase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HAL mRNA
beta-Naphthoflavone results in decreased expression of HAL mRNA

PMID:18164116 PMID:23994337

NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701

G

hepcidin antimicrobial peptide

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HAMP mRNA
beta-Naphthoflavone results in decreased expression of HAMP mRNA

PMID:18164116 PMID:32858204

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

HAUS augmin-like complex, subunit 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HAUS1 mRNA

NCBI chr18:71,275,417...71,286,626
Ensembl chr18:71,273,537...71,286,660

G

hemoglobin subunit beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HBB mRNA

NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012

G

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HCN4 mRNA

NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639

G

histone deacetylase 1

increases expression

beta-Naphthoflavone results in increased expression of HDAC1 protein

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

G

histidine decarboxylase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HDC mRNA

NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341

G

hes family bHLH transcription factor 2

decreases expression

beta-Naphthoflavone results in decreased expression of HES2 mRNA

NCBI chr 5:162,667,190...162,668,235
Ensembl chr 5:162,667,190...162,668,235

G

HIVEP zinc finger 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HIVEP2 mRNA

NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HMGCR mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCR mRNA]

PMID:18164116 PMID:22234961 PMID:31225620

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of HMGCS1 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCS1 mRNA]

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

heme oxygenase 1

multiple interactions
increases expression

[beta-Naphthoflavone co-treated with Copper] results in increased expression of HMOX1 mRNA; [beta-Naphthoflavone co-treated with Lead] results in increased expression of HMOX1 mRNA; [beta-Naphthoflavone co-treated with Mercury] results in increased expression of HMOX1 mRNA
beta-Naphthoflavone results in increased expression of HMOX1 protein
beta-Naphthoflavone results in increased expression of HMOX1 mRNA
isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]

PMID:15297030 PMID:15337587 PMID:19737606 PMID:21295105 PMID:22258563 More...

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

HOP homeobox

decreases expression

beta-Naphthoflavone results in decreased expression of HOPX mRNA

NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909

G

homeobox A1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HOXA1 mRNA

NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504

G

haptoglobin

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of HP mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of HP mRNA

PMID:19737545 PMID:19737606

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

15-hydroxyprostaglandin dehydrogenase

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of HPGD mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HPGD mRNA
beta-Naphthoflavone results in decreased expression of HPGD mRNA

PMID:18164116 PMID:19737545 PMID:32858204

NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228

G

hemopexin

decreases expression

beta-Naphthoflavone results in decreased expression of HPX mRNA

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

G

hydroxysteroid 11-beta dehydrogenase 2

decreases expression

beta-Naphthoflavone results in decreased expression of HSD11B2 mRNA

NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899

G

hydroxysteroid (17-beta) dehydrogenase 1

decreases expression

beta-Naphthoflavone results in decreased expression of HSD17B1 mRNA

NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927

G

hydroxysteroid (17-beta) dehydrogenase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSD17B2 mRNA

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

hydroxysteroid (17-beta) dehydrogenase 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HSD17B6 mRNA

NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425

G

hydroxysteroid (17-beta) dehydrogenase 7

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of HSD17B7 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HSD17B7 mRNA]

NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017

G

heat shock protein 90 alpha family class B member 1

increases expression

beta-Naphthoflavone results in increased expression of HSP90AB1 mRNA

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

G

heat shock protein 90 beta family member 1

decreases expression

beta-Naphthoflavone results in decreased expression of HSP90B1 mRNA

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 12A

decreases expression

beta-Naphthoflavone results in decreased expression of HSPA12A mRNA

NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846

G

heat shock protein family A (Hsp70) member 1A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSPA1A mRNA

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

increases expression

beta-Naphthoflavone results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 4 like

increases expression

beta-Naphthoflavone results in increased expression of HSPA4L mRNA

NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084

G

heat shock protein family A (Hsp70) member 5

increases expression

beta-Naphthoflavone results in increased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family B (small) member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSPB2 mRNA

NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533

G

heat shock protein family B (small) member 8

increases expression

beta-Naphthoflavone results in increased expression of HSPB8 mRNA

NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185

G

HtrA serine peptidase 1

decreases expression

beta-Naphthoflavone results in decreased expression of HTRA1 mRNA

NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379

G

HtrA serine peptidase 4

decreases expression

beta-Naphthoflavone results in decreased expression of HTRA4 mRNA

NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074

G

islet cell autoantigen 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ICA1 mRNA

NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:36,656,475...36,804,298

G

inhibitor of DNA binding 1

decreases expression

beta-Naphthoflavone results in decreased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

inhibitor of DNA binding 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ID4 mRNA

NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470

G

isopentenyl-diphosphate delta isomerase 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IDI1 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of IDI1 mRNA]

PMID:18164116 PMID:22234961 PMID:31225620

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

immediate early response 3

increases expression

beta-Naphthoflavone results in increased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

immediate early response 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IER5 mRNA

NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227

G

interferon-induced protein with tetratricopeptide repeats 3

decreases expression

beta-Naphthoflavone results in decreased expression of IFIT3 mRNA

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

G

interferon induced transmembrane protein 1

decreases expression

beta-Naphthoflavone results in decreased expression of IFITM1 mRNA

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

interferon induced transmembrane protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of IFITM2 mRNA

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

interferon induced transmembrane protein 3

decreases expression

beta-Naphthoflavone results in decreased expression of IFITM3 mRNA

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

immunoglobulin superfamily, DCC subclass, member 4

decreases expression

beta-Naphthoflavone results in decreased expression of IGDCC4 mRNA

PMID:19737606 PMID:32858204

NCBI chr 8:65,621,893...65,657,651
Ensembl chr 8:65,621,897...65,657,648

G

insulin-like growth factor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 1

increases expression

beta-Naphthoflavone results in increased expression of IGFBP1 mRNA

NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IGFBP2 mRNA

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 3

increases expression

beta-Naphthoflavone results in increased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 7

decreases expression

beta-Naphthoflavone results in decreased expression of IGFBP7 mRNA

NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314

G

immunoglobulin superfamily, member 3

decreases expression

beta-Naphthoflavone results in decreased expression of IGSF3 mRNA

NCBI chr 2:188,811,394...188,899,645
Ensembl chr 2:188,811,380...188,899,645

G

immunoglobulin superfamily, member 5

decreases expression

beta-Naphthoflavone results in decreased expression of IGSF5 mRNA

NCBI chr11:35,686,513...35,729,396
Ensembl chr11:35,686,705...35,741,129

G

Indian hedgehog signaling molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IHH mRNA

NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532

G

inhibitor of nuclear factor kappa B kinase subunit epsilon

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of IKBKE mRNA

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

G

interleukin 11

increases expression

beta-Naphthoflavone results in increased expression of IL11 mRNA

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 12A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL12A mRNA

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

G

interleukin 13

multiple interactions

beta-Naphthoflavone promotes the reaction [Plant Extracts results in increased expression of IL13 protein]

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 17A

multiple interactions

beta-Naphthoflavone promotes the reaction [Plant Extracts results in increased expression of IL17A protein]

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 1 alpha

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of IL1A mRNA
[isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA

PMID:8156173 PMID:21295105 PMID:32151702

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

decreases expression
multiple interactions
increases expression

beta-Naphthoflavone results in decreased expression of IL1B mRNA
IL1B protein promotes the reaction [beta-Naphthoflavone results in increased expression of CXCL5 mRNA]
beta-Naphthoflavone results in increased expression of IL1B mRNA

PMID:8156173 PMID:28973351 PMID:32151702 PMID:32858204

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor type 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL1R1 mRNA

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 1 receptor type 2

increases expression

beta-Naphthoflavone results in increased expression of IL1R2 mRNA

NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725

G

interleukin 1 receptor antagonist

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of IL1RN mRNA
beta-Naphthoflavone results in decreased expression of IL1RN mRNA

PMID:32151702 PMID:32858204

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

G

interleukin 20

increases expression

beta-Naphthoflavone results in increased expression of IL20 mRNA

NCBI chr13:42,380,981...42,384,625
Ensembl chr13:42,380,981...42,384,625

G

interleukin 23 subunit alpha

increases expression

beta-Naphthoflavone results in increased expression of IL23A mRNA

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

G

interleukin 24

increases expression

beta-Naphthoflavone results in increased expression of IL24 mRNA

NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487

G

interleukin 2 receptor subunit beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL2RB mRNA

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

G

interleukin 36, gamma

increases expression

beta-Naphthoflavone results in increased expression of IL36G mRNA

NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480

G

interleukin 5

multiple interactions

beta-Naphthoflavone promotes the reaction [Plant Extracts results in increased expression of IL5 protein]

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL6 mRNA
beta-Naphthoflavone results in increased expression of IL6 mRNA

PMID:8156173 PMID:21295105 PMID:32151702

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

ilvB acetolactate synthase like

decreases expression

beta-Naphthoflavone results in decreased expression of ILVBL mRNA

NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924

G

inhibin subunit beta B

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of INHBB mRNA
beta-Naphthoflavone results in decreased expression of INHBB mRNA

PMID:18164116 PMID:19737606

NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832

G

inhibin subunit beta E

increases expression

beta-Naphthoflavone results in increased expression of INHBE mRNA

NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172

G

insulin induced gene 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of INSIG2 mRNA

NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923

G

interleukin-1 receptor-associated kinase 2

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of IRAK2 mRNA
beta-Naphthoflavone results in decreased expression of IRAK2 mRNA

PMID:32151702 PMID:32858204

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

G

interferon regulatory factor 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IRF1 mRNA
beta-Naphthoflavone results in decreased expression of IRF1 mRNA

PMID:18164116 PMID:32858204

NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166

G

interferon regulatory factor 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IRF7 mRNA

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

immunity-related GTPase M

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of IRGM mRNA]

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

G

insulin receptor substrate 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IRS2 mRNA

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

G

ISG15 ubiquitin-like modifier

decreases expression

beta-Naphthoflavone results in decreased expression of ISG15 mRNA

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

G

interferon stimulated exonuclease gene 20

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ISG20 mRNA

NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027

G

isthmin 2

decreases expression

beta-Naphthoflavone results in decreased expression of ISM2 mRNA

NCBI chr 6:106,921,213...106,944,291
Ensembl chr 6:106,926,175...106,944,514

G

integrin subunit alpha 5

decreases expression

beta-Naphthoflavone results in decreased expression of ITGA5 mRNA

NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837

G

integrin subunit alpha 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ITGA8 mRNA

NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510

G

integrin subunit beta 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ITGB6 mRNA

NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671

G

intelectin 1

decreases expression

beta-Naphthoflavone results in decreased expression of ITLN1 mRNA

NCBI chr13:83,932,234...83,958,243
Ensembl chr13:83,948,124...83,958,227

G

inositol-trisphosphate 3-kinase B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ITPKB mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ITPKB mRNA

NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004

G

involucrin

increases expression

beta-Naphthoflavone results in increased expression of IVL mRNA

NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100

G

junctional adhesion molecule 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of JAM2 mRNA

NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063

G

Josephin domain containing 1

increases expression

beta-Naphthoflavone results in increased expression of JOSD1 mRNA

NCBI chr 7:111,230,318...111,244,241
Ensembl chr 7:111,230,318...111,244,652

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions

beta-Naphthoflavone promotes the reaction [JUN protein binds to NQO1 promoter]

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

beta-Naphthoflavone results in increased expression of JUNB mRNA

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

JunD proto-oncogene, AP-1 transcription factor subunit

increases expression

beta-Naphthoflavone results in increased expression of JUND mRNA

NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799

G

kalirin, RhoGEF kinase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KALRN mRNA

NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610

G

KN motif and ankyrin repeat domains 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KANK1 mRNA

NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514

G

potassium voltage-gated channel subfamily A member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KCNA2 mRNA

NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400

G

potassium sodium-activated channel subfamily T member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KCNT2 mRNA

NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987

G

kinesin family member 12

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KIF12 mRNA

NCBI chr 5:76,596,204...76,603,261
Ensembl chr 5:76,596,208...76,602,843

G

kinesin family member 22

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KIF22 mRNA

NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401

G

kinesin family member 4A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KIF4 mRNA

NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139

G

KiSS-1 metastasis-suppressor

decreases expression

beta-Naphthoflavone results in decreased expression of KISS1 mRNA

NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612

G

KLF transcription factor 2

increases expression

beta-Naphthoflavone results in increased expression of KLF2 mRNA

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

KLF transcription factor 6

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of KLF6 mRNA
[CYP2E1 protein co-treated with beta-Naphthoflavone] results in increased expression of KLF6 protein

PMID:19737606 PMID:22486562

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

kelch domain containing 8B

decreases expression

beta-Naphthoflavone results in decreased expression of KLHDC8B mRNA

NCBI chr 8:109,141,594...109,146,584
Ensembl chr 8:109,141,594...109,146,918

G

kallikrein related-peptidase 14

increases expression

beta-Naphthoflavone results in increased expression of KLK14 mRNA

NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240

G

killer cell lectin like receptor G1

increases expression

beta-Naphthoflavone results in increased expression of KLRG1 mRNA

NCBI chr 4:155,455,465...155,467,301
Ensembl chr 4:155,455,495...155,467,424

G

kinetochore-localized astrin/SPAG5 binding protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KNSTRN mRNA

NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715

G

karyopherin subunit alpha 6

increases expression

beta-Naphthoflavone results in increased expression of KPNA6 mRNA

NCBI chr 5:141,988,111...142,021,483
Ensembl chr 5:141,991,568...142,021,120

G

keratin 1

affects expression

beta-Naphthoflavone affects the expression of KRT1 mRNA

NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844

G

keratin 10

decreases expression

beta-Naphthoflavone results in decreased expression of KRT10 mRNA

NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701

G

keratin 13

increases expression

beta-Naphthoflavone results in increased expression of KRT13 mRNA

NCBI chr10:85,051,887...85,056,099
Ensembl chr10:85,051,889...85,056,084

G

keratin 14

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KRT14 mRNA

NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799

G

keratin 19

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KRT19 mRNA
beta-Naphthoflavone results in increased expression of KRT19 mRNA

PMID:18164116 PMID:32151702

NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799

G

keratin 20

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KRT20 mRNA

NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107

G

keratin 23

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KRT23 mRNA
beta-Naphthoflavone results in decreased expression of KRT23 mRNA

PMID:18164116 PMID:32858204

NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983

G

keratin 31

increases expression

beta-Naphthoflavone results in increased expression of KRT31 mRNA

NCBI chr10:84,979,393...84,982,898
Ensembl chr10:84,979,352...84,982,832

G

keratin 34

increases expression

beta-Naphthoflavone results in increased expression of KRT34 mRNA

NCBI chr10:84,969,988...84,974,098
Ensembl chr10:84,970,017...84,974,040

G

keratin 5

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of KRT5 mRNA

NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850

G

keratin 78

increases expression

beta-Naphthoflavone results in increased expression of KRT78 mRNA

NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021

G

keratin associated protein 3-3

increases expression

beta-Naphthoflavone results in increased expression of KRTAP3-3 mRNA

NCBI chr10:84,511,459...84,511,758
Ensembl chr10:84,511,092...84,511,812
Ensembl chr10:84,511,092...84,511,812

G

keratinocyte differentiation associated protein

increases expression

beta-Naphthoflavone results in increased expression of KRTDAP mRNA

NCBI chr 1:86,038,296...86,041,594
Ensembl chr 1:86,038,437...86,041,455

G

kynureninase

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of KYNU mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KYNU mRNA

PMID:18164116 PMID:19737606

NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488

G

lactalbumin, alpha

multiple interactions
decreases expression

AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of LALBA mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of LALBA mRNA]

NCBI chr 7:129,625,531...129,628,034
Ensembl chr 7:129,625,535...129,628,061

G

laminin subunit alpha 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

laminin subunit beta 3

increases expression

beta-Naphthoflavone results in increased expression of LAMB3 mRNA

NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405

G

lipopolysaccharide binding protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LBP mRNA

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

G

leptin

decreases expression

beta-Naphthoflavone results in decreased expression of LEP mRNA

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

leptin receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LEPR mRNA

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

G

galectin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LGALS1 mRNA

NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345

G

galectin 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LGALS2 mRNA

NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802

G

galectin 3

increases expression

beta-Naphthoflavone results in increased expression of LGALS3 mRNA

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

galectin 3 binding protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LGALS3BP mRNA

NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256

G

legumain

decreases expression

beta-Naphthoflavone results in decreased expression of LGMN mRNA

NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480

G

luteinizing hormone/choriogonadotropin receptor

multiple interactions

beta-Naphthoflavone inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]

NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521

G

LIF, interleukin 6 family cytokine

increases expression

beta-Naphthoflavone results in increased expression of LIF mRNA

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

G

LIM and calponin homology domains 1

decreases expression

beta-Naphthoflavone results in decreased expression of LIMCH1 mRNA

NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191

G

LIM and cysteine-rich domains 1

increases expression

beta-Naphthoflavone results in increased expression of LMCD1 mRNA

NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046

G

LIM domain 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LMO7 mRNA

NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783

G

leucyl and cystinyl aminopeptidase

decreases expression

beta-Naphthoflavone results in decreased expression of LNPEP mRNA

NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544

G

small proline-rich protein 2I-like

increases expression

beta-Naphthoflavone results in increased expression of SPRR2A mRNA

NCBI chr 2:177,815,964...177,816,236
Ensembl chr 2:177,815,964...177,816,236

G

loricrin cornified envelope precursor protein

decreases expression

beta-Naphthoflavone results in decreased expression of LORICRIN mRNA

NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807

G

lysyl oxidase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LOX mRNA

NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477

G

lysyl oxidase-like 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LOXL1 mRNA

NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356

G

lysophosphatidic acid receptor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LPAR1 mRNA

NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895

G

lysophosphatidic acid receptor 6

increases expression

beta-Naphthoflavone results in increased expression of LPAR6 mRNA

NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331

G

lipin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

lipin 2

increases expression

beta-Naphthoflavone results in increased expression of LPIN2 mRNA

NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193

G

lipoprotein lipase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LPL mRNA
beta-Naphthoflavone results in decreased expression of LPL mRNA

PMID:18164116 PMID:32858204

NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249

G

lecithin retinol acyltransferase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LRAT mRNA

NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619

G

LDL receptor related protein 2

increases expression

beta-Naphthoflavone results in increased expression of LRP2 mRNA

NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708

G

leucine rich repeat containing 25

increases expression

beta-Naphthoflavone results in increased expression of LRRC25 mRNA

NCBI chr16:18,806,888...18,813,723
Ensembl chr16:18,806,890...18,813,671

G

leucine rich repeat containing 32

decreases expression

beta-Naphthoflavone results in decreased expression of LRRC32 mRNA

NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373

G

leucine rich repeat neuronal 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LRRN3 mRNA

NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330

G

lanosterol synthase

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of LSS mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of LSS mRNA]

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

lymphotoxin beta

increases expression

beta-Naphthoflavone results in increased expression of LTB mRNA

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

G

latent transforming growth factor beta binding protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LTBP1 mRNA

NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349

G

latent transforming growth factor beta binding protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LTBP2 mRNA

NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208

G

latent transforming growth factor beta binding protein 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LTBP3 mRNA

NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975

G

leukotriene C4 synthase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LTC4S mRNA

NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651

G

latexin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LXN mRNA

NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460

G

Ly6-C antigen

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LY6C mRNA

NCBI chr 7:106,959,508...106,963,329
Ensembl chr 7:106,959,511...106,963,329

G

lysozyme-like 1

decreases expression

beta-Naphthoflavone results in decreased expression of LYZL1 mRNA

NCBI chr17:53,530,437...53,543,877
Ensembl chr17:53,530,442...53,543,866

G

MAF bZIP transcription factor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAF mRNA

NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365

G

MAF bZIP transcription factor B

increases expression

beta-Naphthoflavone results in increased expression of MAFB mRNA

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

G

MAF bZIP transcription factor F

increases expression

beta-Naphthoflavone results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

MAF bZIP transcription factor G

increases expression

beta-Naphthoflavone results in increased expression of MAFG mRNA

PMID:32151702 PMID:32858204

NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026

G

MAF bZIP transcription factor K

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAFK mRNA

NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048

G

MAGE family member D1

decreases expression

beta-Naphthoflavone results in decreased expression of MAGED1 mRNA

NCBI chr X:59,422,715...59,429,381
Ensembl chr X:59,422,717...59,429,364

G

MAGE family member D2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAGED2 mRNA

NCBI chr X:19,733,593...19,741,769
Ensembl chr X:19,733,597...19,740,477

G

MAGE family member H1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAGEH1 mRNA

NCBI chr X:18,350,015...18,351,271
Ensembl chr X:18,349,774...18,351,516

G

mannosidase, alpha, class 1C, member 1

decreases expression

beta-Naphthoflavone results in decreased expression of MAN1C1 mRNA

NCBI chr 5:146,774,282...146,913,257
Ensembl chr 5:146,775,842...146,913,421

G

monoamine oxidase A

decreases expression

beta-Naphthoflavone results in decreased expression of MAOA mRNA

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

G

mitogen activated protein kinase kinase 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MAP2K5 mRNA

NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions

beta-Naphthoflavone results in increased phosphorylation of MAPK1 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MAPK1 mRNA

PMID:18164116 PMID:23228475

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

increases phosphorylation

beta-Naphthoflavone results in increased phosphorylation of MAPK3 protein

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

MAPK activated protein kinase 5

increases expression

beta-Naphthoflavone results in increased expression of MAPKAPK5 mRNA

NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052

G

microtubule-associated protein tau

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAPT mRNA

NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129

G

methionine adenosyltransferase 2 non-catalytic beta subunit

increases expression

beta-Naphthoflavone results in increased expression of MAT2B mRNA

NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777

G

myelin basic protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MBP mRNA

NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404

G

mast cell-expressed membrane protein 1

increases expression

beta-Naphthoflavone results in increased expression of MCEMP1 mRNA

NCBI chr12:1,721,781...1,727,350
Ensembl chr12:1,718,730...1,725,986

G

minichromosome maintenance complex component 3 associated protein

increases expression

beta-Naphthoflavone results in increased expression of MCM3AP mRNA

NCBI chr20:12,127,570...12,165,165
Ensembl chr20:12,127,570...12,165,165

G

malate dehydrogenase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MDH1 mRNA

NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925

G

MDM2 proto-oncogene

increases phosphorylation

beta-Naphthoflavone results in increased phosphorylation of MDM2 protein

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

MDM4 regulator of p53

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MDM4 mRNA

NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226

G

malic enzyme 1

increases expression

beta-Naphthoflavone results in increased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

methyl CpG binding protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MECP2 mRNA

NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689

G

multiple EGF-like-domains 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MEGF8 mRNA

NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613

G

mesenchyme homeobox 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MEOX2 mRNA

NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467

G

mesoderm specific transcript

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MEST mRNA

NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145

G

microfibril associated protein 4

decreases expression

beta-Naphthoflavone results in decreased expression of MFAP4 mRNA

NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155

G

MFSD2 lysolipid transporter A, lysophospholipid

decreases expression

beta-Naphthoflavone results in decreased expression of MFSD2A mRNA

NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690

G

matrix Gla protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MGP mRNA

NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667

G

microsomal glutathione S-transferase 1

increases expression

beta-Naphthoflavone results in increased expression of MGST1 mRNA

NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892

G

MID1 interacting protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MID1IP1 mRNA

NCBI chr X:12,060,993...12,063,318
Ensembl chr X:12,060,883...12,065,774

G

meiosis regulator for oocyte development

increases expression

beta-Naphthoflavone results in increased expression of MIOS mRNA

NCBI chr 4:36,263,419...36,289,546
Ensembl chr 4:36,263,968...36,289,544

G

MAPK interacting serine/threonine kinase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MKNK2 mRNA

NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827

G

monocyte to macrophage differentiation-associated

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMD mRNA

NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528

G

membrane metallo-endopeptidase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MME mRNA

NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792

G

matrix metallopeptidase 10

increases expression

beta-Naphthoflavone results in increased expression of MMP10 mRNA

NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748

G

matrix metallopeptidase 11

decreases expression

beta-Naphthoflavone results in decreased expression of MMP11 mRNA

NCBI chr20:12,730,846...12,739,629
Ensembl chr20:12,730,836...12,739,628

G

matrix metallopeptidase 12

increases expression

beta-Naphthoflavone results in increased expression of MMP12 mRNA

NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611

G

matrix metallopeptidase 14

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MMP14 mRNA

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

G

matrix metallopeptidase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMP2 mRNA

PMID:18164116 PMID:20045035

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 23

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMP23 mRNA
beta-Naphthoflavone results in decreased expression of MMP23 mRNA

PMID:18164116 PMID:23994337

NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433

G

matrix metallopeptidase 3

increases expression

beta-Naphthoflavone results in increased expression of MMP3 mRNA

NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961

G

matrix metallopeptidase 9

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of MMP9 mRNA
beta-Naphthoflavone results in decreased expression of MMP9 mRNA

PMID:32151702 PMID:32858204

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

myelin protein zero-like 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MPZL1 mRNA

NCBI chr13:77,852,467...77,889,305
Ensembl chr13:77,852,467...77,896,616

G

mitochondrial ribosomal protein L37

increases expression

beta-Naphthoflavone results in increased expression of MRPL37 mRNA

NCBI chr 5:121,827,892...121,846,187
Ensembl chr 5:121,829,111...121,846,176

G

mitochondrial ribosomal protein S24

increases expression

beta-Naphthoflavone results in increased expression of MRPS24 mRNA

NCBI chr14:80,584,671...80,588,801
Ensembl chr14:80,584,673...80,588,871

G

methylsterol monooxygenase 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MSMO1 mRNA
beta-Naphthoflavone results in decreased expression of MSMO1 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of MSMO1 mRNA]

PMID:18164116 PMID:22234961

NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016

G

methionine sulfoxide reductase A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MSRA mRNA

NCBI chr15:38,363,459...38,677,406
Ensembl chr15:38,351,445...38,676,585

G

metallothionein 1

decreases expression

beta-Naphthoflavone results in decreased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 1, pseudogene 3

decreases expression

beta-Naphthoflavone results in decreased expression of MT1E mRNA

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2A

decreases expression

beta-Naphthoflavone results in decreased expression of MT2A mRNA

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

myotubularin related protein 10

decreases expression

beta-Naphthoflavone results in decreased expression of MTMR10 mRNA

NCBI chr 1:117,859,355...117,910,839
Ensembl chr 1:117,859,267...117,910,849

G

microtubule associated scaffold protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MTUS1 mRNA

NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793

G

mucin 1, cell surface associated

decreases expression

beta-Naphthoflavone results in decreased expression of MUC1 mRNA

NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733

G

major urinary protein 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MUP4 mRNA

NCBI chr 5:74,961,143...74,964,686
Ensembl chr 5:74,842,319...75,061,474

G

mevalonate diphosphate decarboxylase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MVD mRNA
beta-Naphthoflavone results in decreased expression of MVD mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of MVD mRNA]

PMID:18164116 PMID:22234961 PMID:31225620

NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971

G

mevalonate kinase

decreases expression

beta-Naphthoflavone results in decreased expression of MVK mRNA

NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882

G

myosin binding protein H

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MYBPH mRNA

NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893

G

myosin heavy chain 10

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MYH10 mRNA

NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165

G

myoferlin

increases expression

beta-Naphthoflavone results in increased expression of MYOF mRNA

NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334

G

myozenin 2

increases expression

beta-Naphthoflavone results in increased expression of MYOZ2 mRNA

NCBI chr 2:211,141,463...211,168,187
Ensembl chr 2:211,141,463...211,168,221

G

N-acetylated alpha-linked acidic dipeptidase 2

decreases expression

beta-Naphthoflavone results in decreased expression of NAALAD2 mRNA

NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:15,407,043...15,479,714

G

Na+ dependent glucose transporter 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NAGLT1 mRNA

NCBI chr20:43,411,550...43,423,873
Ensembl chr20:43,394,843...43,423,873

G

N-acetyltransferase 8 (GCN5-related) family member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NAT8F1 mRNA

NCBI chr 4:118,336,208...118,342,923
Ensembl chr 4:118,332,862...118,344,035

G

N-acetyltransferase 8 (GCN5-related) family member 2

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of NAT8F2 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of NAT8F2 mRNA]

NCBI chr 4:118,319,984...118,323,159
Ensembl chr 4:118,319,988...118,324,395

G

neuron navigator 2

decreases expression

beta-Naphthoflavone results in decreased expression of NAV2 mRNA

NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337

G

neutrophil cytosolic factor 1

increases expression

beta-Naphthoflavone results in increased expression of NCF1 mRNA

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

G

N-terminal EF-hand calcium binding protein 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of NECAB1 mRNA

NCBI chr 5:28,357,859...28,578,642
Ensembl chr 5:28,357,859...28,578,642
Ensembl chr 5:28,357,859...28,578,642

G

nectin cell adhesion molecule 3

decreases expression

beta-Naphthoflavone results in decreased expression of NECTIN3 mRNA

NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519

G

NFE2 like bZIP transcription factor 2

increases expression

beta-Naphthoflavone results in increased expression of NFE2L2 protein

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NFE2 like bZIP transcription factor 3

increases expression

beta-Naphthoflavone results in increased expression of NFE2L3 mRNA

NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629

G

nuclear factor, interleukin 3 regulated

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

NFKB inhibitor alpha

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA]
beta-Naphthoflavone results in increased expression of NFKBIA mRNA

PMID:20045035 PMID:32151702

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor epsilon

increases expression

beta-Naphthoflavone results in increased expression of NFKBIE mRNA

NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437

G

NFKB inhibitor zeta

increases expression

beta-Naphthoflavone results in increased expression of NFKBIZ mRNA

NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723

G

NFS1 cysteine desulfurase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFS1 mRNA

NCBI chr 3:144,637,309...144,659,660
Ensembl chr 3:144,637,309...144,659,666

G

neuroglobin

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of NGB mRNA

NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830

G

nidogen 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NID2 mRNA

NCBI chr15:4,458,082...4,513,808
Ensembl chr15:4,458,084...4,513,843

G

NIPA-like domain containing 4

decreases expression

beta-Naphthoflavone results in decreased expression of NIPAL4 mRNA

NCBI chr10:30,583,926...30,600,640
Ensembl chr10:30,583,926...30,600,640

G

nicotinamide nucleotide adenylyltransferase 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NMNAT3 mRNA

NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645

G

nicotinamide riboside kinase 2

decreases expression

beta-Naphthoflavone results in decreased expression of NMRK2 mRNA

NCBI chr 7:8,514,855...8,517,916
Ensembl chr 7:8,514,927...8,517,922

G

nocturnin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOCT mRNA

NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400

G

nucleolar protein 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOL3 mRNA

NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250

G

Nodal modulator 1

increases expression

beta-Naphthoflavone results in increased expression of NOMO1 mRNA

NCBI chr 1:96,505,460...96,556,280
Ensembl chr 1:96,505,484...96,556,279

G

nitric oxide synthase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA]

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

nitric oxide synthase 3

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of NOS3 mRNA
beta-Naphthoflavone results in decreased expression of NOS3 protein
[Triclosan co-treated with beta-Naphthoflavone] results in decreased expression of NOS3 protein

PMID:32858204 PMID:33722737

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

notch receptor 1

increases expression

beta-Naphthoflavone results in increased expression of NOTCH1 mRNA

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

NADPH oxidase 4

increases expression

beta-Naphthoflavone results in increased expression of NOX4 mRNA

NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406

G

neural proliferation, differentiation and control, 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NPDC1 mRNA

NCBI chr 3:8,220,446...8,226,446
Ensembl chr 3:8,213,663...8,226,866

G

nephrocystin 1

increases expression

beta-Naphthoflavone results in increased expression of NPHP1 mRNA

NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234

G

natriuretic peptide A

increases expression

beta-Naphthoflavone results in increased expression of NPPA mRNA

NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351

G

natriuretic peptide B

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of NPPB mRNA
beta-Naphthoflavone results in decreased expression of NPPB mRNA

PMID:19969063 PMID:32858204

NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168

G

NAD(P)H quinone dehydrogenase 1

increases expression
increases activity
multiple interactions

beta-Naphthoflavone results in increased expression of NQO1 mRNA; beta-Naphthoflavone results in increased expression of NQO1 protein
beta-Naphthoflavone results in increased activity of NQO1 protein
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of NQO1 mRNA; [beta-Naphthoflavone results in increased expression of NQO1 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; [beta-Naphthoflavone results in increased expression of NQO1 protein] which results in decreased susceptibility to Oxygen; beta-Naphthoflavone affects the reaction [Oxygen results in increased expression of NQO1 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of NQO1 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of NQO1 protein]; Cadmium inhibits the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]; Chromium inhibits the reaction [beta-Naphthoflavone results in increased activity of NQO1 protein]; Chromium inhibits the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]; Lipopolysaccharides inhibits the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]; Oxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of NQO1 protein]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NQO1 mRNA
beta-Naphthoflavone promotes the reaction [FOS protein binds to NQO1 promoter]; beta-Naphthoflavone promotes the reaction [JUN protein binds to NQO1 promoter]; CYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 protein]]; CYP1A2 gene mutant form promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]

PMID:8375015 PMID:14510636 PMID:15337587 PMID:15627257 PMID:16906435 More...

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

N-ribosyldihydronicotinamide:quinone dehydrogenase 2

increases expression

beta-Naphthoflavone results in increased expression of NQO2 mRNA

NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320

G

nuclear receptor subfamily 1, group D, member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NR1D1 mRNA

NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705

G

nuclear receptor subfamily 1, group D, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NR1D2 mRNA

NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553

G

nuclear receptor subfamily 1, group H, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NR1H2 mRNA

NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377

G

nuclear receptor subfamily 1, group H, member 3

decreases expression

beta-Naphthoflavone results in decreased expression of NR1H3 mRNA

NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722

G

nuclear receptor subfamily 1, group H, member 4

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NR1H4 mRNA
beta-Naphthoflavone results in decreased expression of NR1H4 mRNA

PMID:18164116 PMID:19737606

NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047

G

nuclear receptor subfamily 1, group I, member 2

decreases expression
increases activity
multiple interactions

beta-Naphthoflavone results in decreased expression of NR1I2 mRNA
beta-Naphthoflavone results in increased activity of NR1I2 protein
NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]]

PMID:20607812 PMID:25680588 PMID:28428138

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

increases expression

beta-Naphthoflavone results in increased expression of NR1I3 mRNA

PMID:17627975 PMID:25949234

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 2, group F, member 1

affects binding

[beta-Naphthoflavone binds to AHR protein] which binds to NR2F1 protein

NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123

G

neuregulin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NRG1 mRNA

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

neurturin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NRTN mRNA

NCBI chr 9:1,581,860...1,587,835
Ensembl chr 9:1,581,975...1,583,102

G

NAD(P) dependent steroid dehydrogenase-like

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of NSDHL mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of NSDHL mRNA]

NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142

G

NSFL1 cofactor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NSFL1C mRNA

NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870

G

5' nucleotidase, ecto

decreases expression

beta-Naphthoflavone results in decreased expression of NT5E mRNA

NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881

G

neurotrophin 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NTF3 mRNA

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

G

NUAK family kinase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NUAK2 mRNA

NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604

G

nuclear protein 1, transcriptional regulator

increases expression

beta-Naphthoflavone results in increased expression of NUPR1 mRNA

NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281

G

2'-5' oligoadenylate synthetase 1A

decreases expression

beta-Naphthoflavone results in decreased expression of OAS1 mRNA

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

G

2'-5'-oligoadenylate synthetase-like

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of OASL1 mRNA

NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641

G

occludin

increases expression

beta-Naphthoflavone results in increased expression of OCLN mRNA

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

G

odontogenesis associated phosphoprotein

decreases expression

beta-Naphthoflavone results in decreased expression of ODAPH mRNA

NCBI chr14:16,071,835...16,080,151
Ensembl chr14:16,073,058...16,080,129

G

olfactomedin-like 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of OLFML1 mRNA

NCBI chr 1:161,478,129...161,502,541
Ensembl chr 1:161,478,242...161,502,537

G

olfactory receptor 59

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of OLR59 mRNA

NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179

G

olfactory receptor family 5 subfamily M member 11

increases expression

beta-Naphthoflavone results in increased expression of OR5M11B mRNA

NCBI chr 3:71,017,564...71,018,538
Ensembl chr 3:71,017,564...71,018,538

G

olfactory receptor family 9 subfamily S member 23B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of OR9S23B mRNA

NCBI chr 9:93,117,328...93,118,299
Ensembl chr 9:93,115,232...93,123,441

G

orosomucoid 1

increases expression

beta-Naphthoflavone results in increased expression of ORM1 mRNA

NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154

G

oxidative stress induced growth inhibitor 1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of OSGIN1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of OSGIN1 mRNA

PMID:18164116 PMID:19737606 PMID:32858204

NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516

G

prolyl 3-hydroxylase 2

decreases expression

beta-Naphthoflavone results in decreased expression of P3H2 mRNA

NCBI chr11:74,634,267...74,775,422
Ensembl chr11:74,634,267...74,775,421

G

phenylalanine hydroxylase

decreases expression

beta-Naphthoflavone results in decreased expression of PAH mRNA

NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130

G

pannexin 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PANX2 mRNA

NCBI chr 7:120,139,259...120,153,056
Ensembl chr 7:120,139,294...120,152,361

G

pappalysin

decreases expression

beta-Naphthoflavone results in decreased expression of PAPPA mRNA

NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666

G

pyruvate carboxylase

increases expression

beta-Naphthoflavone results in increased expression of PC mRNA

NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380

G

protocadherin alpha 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCDHA4 mRNA

NCBI chr18:28,581,040...28,846,214
Ensembl chr18:28,581,225...28,846,211

G

protocadherin beta 19

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCDHB12 mRNA

NCBI chr18:29,204,838...29,207,646

G

PCNA clamp associated factor

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCLAF mRNA
beta-Naphthoflavone results in decreased expression of PCLAF mRNA

PMID:18164116 PMID:32858204

NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994

G

proliferating cell nuclear antigen

increases expression

beta-Naphthoflavone results in increased expression of PCNA protein

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

procollagen C-endopeptidase enhancer

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCOLCE mRNA

NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508

G

Purkinje cell protein 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCP4 mRNA

NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725

G

proprotein convertase subtilisin/kexin type 9

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCSK9 mRNA
beta-Naphthoflavone results in decreased expression of PCSK9 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of PCSK9 mRNA]

PMID:18164116 PMID:22234961

NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688

G

platelet derived growth factor subunit A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PDGFA mRNA

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

G

pyruvate dehydrogenase kinase 4

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PDK4 mRNA
beta-Naphthoflavone results in increased expression of PDK4 mRNA

PMID:18164116 PMID:32858204

NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850

G

PDZ and LIM domain 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PDLIM3 mRNA

NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657

G

PDZ domain containing RING finger 3

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of PDZRN3 mRNA

NCBI chr 4:133,770,736...133,996,959
Ensembl chr 4:133,770,736...133,996,959

G

pelota mRNA surveillance and ribosome rescue factor

increases expression

beta-Naphthoflavone results in increased expression of PELO mRNA

NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746

G

period circadian regulator 1

multiple interactions
decreases expression

beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to PER1 promoter]; beta-Naphthoflavone inhibits the reaction [Colforsin results in increased expression of PER1 mRNA]; beta-Naphthoflavone promotes the reaction [AHR protein binds to PER1 promoter]
beta-Naphthoflavone results in decreased expression of PER1 mRNA; beta-Naphthoflavone results in decreased expression of PER1 protein

PMID:20106950 PMID:23291558

NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431

G

period circadian regulator 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PER2 mRNA

NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459

G

peroxisomal biogenesis factor 11 alpha

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PEX11A mRNA

NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172

G

platelet factor 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PF4 mRNA

NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365

G

phosphofructokinase, liver type

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PFKL mRNA

NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315

G

profilin 2

increases expression

beta-Naphthoflavone results in increased expression of PFN2 mRNA

NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938

G

post-GPI attachment to proteins phospholipase 3

decreases expression

beta-Naphthoflavone results in decreased expression of PGAP3 mRNA

NCBI chr10:83,387,113...83,399,357
Ensembl chr10:83,387,113...83,398,628

G

pyroglutamyl-peptidase I

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PGPEP1 mRNA

NCBI chr16:18,770,563...18,782,968
Ensembl chr16:18,771,021...18,783,478

G

phosphoglycerate dehydrogenase

increases expression

beta-Naphthoflavone results in increased expression of PHGDH mRNA

NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944

G

pleckstrin homology-like domain, family A, member 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PHLDA3 mRNA

NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335

G

phosphoethanolamine/phosphocholine phosphatase 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of PHOSPHO1 mRNA

NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342

G

phosphatidylinositol-5-phosphate 4-kinase type 2 gamma

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PIP4K2C mRNA

NCBI chr 7:63,020,004...63,035,086
Ensembl chr 7:63,020,000...63,035,078

G

pirin

increases expression

beta-Naphthoflavone results in increased expression of PIR mRNA

NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218

G

paired-like homeodomain 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PITX1 mRNA

NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291

G

PBX/knotted 1 homeobox 1

increases expression

beta-Naphthoflavone results in increased expression of PKNOX1 mRNA

NCBI chr20:9,662,866...9,705,030
Ensembl chr20:9,662,899...9,703,727

G

phospholipase A1 member A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLA1A mRNA

NCBI chr11:62,320,112...62,357,779
Ensembl chr11:62,320,493...62,357,779

G

phospholipase A2 group IB

decreases expression

beta-Naphthoflavone results in decreased expression of PLA2G1B mRNA

NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226

G

phospholipase A2, group IIC

increases expression

beta-Naphthoflavone results in increased expression of PLA2G2C mRNA

NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377

G

phospholipase A2 group IVA

increases expression

beta-Naphthoflavone results in increased expression of PLA2G4A mRNA

NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266

G

phospholipase A2 group VII

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLA2G7 mRNA

NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476

G

placenta enriched 1

decreases expression

beta-Naphthoflavone results in decreased expression of PLAC1 mRNA

NCBI chr X:132,821,347...132,955,143
Ensembl chr X:132,821,347...132,985,668

G

plasminogen activator, tissue type

increases expression

beta-Naphthoflavone results in increased expression of PLAT mRNA

NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223

G

plasminogen activator, urokinase

increases expression

beta-Naphthoflavone results in increased expression of PLAU mRNA

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

plasminogen activator, urokinase receptor

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of PLAUR mRNA
beta-Naphthoflavone results in decreased expression of PLAUR mRNA

PMID:32151702 PMID:32858204

NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595

G

phospholipase C, delta 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLCD1 mRNA

NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186

G

phospholipase D2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PLD2 mRNA

NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808

G

pleckstrin

decreases expression

beta-Naphthoflavone results in decreased expression of PLEK mRNA

NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131

G

pleckstrin homology domain containing A4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLEKHA4 mRNA

NCBI chr 1:96,005,824...96,028,826
Ensembl chr 1:96,006,000...96,028,826

G

perilipin 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

polo-like kinase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLK mRNA

NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400

G

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLOD2 mRNA
beta-Naphthoflavone results in decreased expression of PLOD2 mRNA

PMID:18164116 PMID:32858204

NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255

G

phospholipid scramblase 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of PLSCR1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLSCR1 mRNA

PMID:18164116 PMID:19737545

NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692

G

peripheral myelin protein 22

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PMP22 mRNA

NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714

G

phosphomevalonate kinase

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of PMVK mRNA]

NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364

G

prepronociceptin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PNOC mRNA

NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867

G

proline-rich nuclear receptor coactivator 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PNRC1 mRNA

NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161

G

protein O-glucosyltransferase 3

decreases expression

beta-Naphthoflavone results in decreased expression of POGLUT3 mRNA

NCBI chr 8:53,777,614...53,795,404
Ensembl chr 8:53,777,785...53,795,399

G

DNA polymerase beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of POLB mRNA

NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812

G

cytochrome p450 oxidoreductase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of POR mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of POR mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of POR mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of POR protein

PMID:18164116 PMID:19737545 PMID:21295105 PMID:30842367

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

POU class 3 homeobox 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of POU3F1 mRNA

NCBI chr 5:136,910,391...136,913,371
Ensembl chr 5:136,910,391...136,913,371

G

peroxisome proliferator activated receptor alpha

multiple interactions
increases expression

AHR affects the reaction [beta-Naphthoflavone results in increased expression of PPARA mRNA]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of PPARA protein]; alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of PPARA protein]; BMAL1 affects the reaction [beta-Naphthoflavone results in increased expression of PPARA mRNA]
beta-Naphthoflavone results in increased expression of PPARA mRNA; beta-Naphthoflavone results in increased expression of PPARA protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PPARA mRNA

PMID:18164116 PMID:21849270

NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor delta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PPARD mRNA

NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968

G

peroxisome proliferator-activated receptor gamma

multiple interactions

beta-Naphthoflavone inhibits the reaction [Triclosan results in increased expression of PPARG protein]

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPFIA binding protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of PPFIBP2 mRNA

NCBI chr 1:161,504,774...161,687,339
Ensembl chr 1:161,504,890...161,655,212

G

peptidylprolyl isomerase like 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PPIL2 mRNA

NCBI chr11:83,897,719...83,920,970
Ensembl chr11:83,897,764...83,922,144

G

protein phosphatase, Mg2+/Mn2+ dependent, 1F

decreases expression

beta-Naphthoflavone results in decreased expression of PPM1F mRNA

NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340

G

protein phosphatase 1, regulatory (inhibitor) subunit 14c

decreases expression

beta-Naphthoflavone results in decreased expression of PPP1R14C mRNA

NCBI chr 1:39,773,403...39,886,970
Ensembl chr 1:39,773,403...39,886,956

G

protein phosphatase 2 regulatory subunit B', epsilon

increases expression

beta-Naphthoflavone results in increased expression of PPP2R5E mRNA

NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872

G

protein phosphatase 4, regulatory subunit 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PPP4R1 mRNA

NCBI chr 9:105,391,271...105,450,626
Ensembl chr 9:105,391,412...105,450,633

G

proteoglycan 2, pro eosinophil major basic protein

decreases expression

beta-Naphthoflavone results in decreased expression of PRG2 mRNA

NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101

G

prolactin

multiple interactions
decreases expression

alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of PRL mRNA]
beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of CSN2 mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of LALBA mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of WAP mRNA]; beta-Naphthoflavone promotes the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of CYP1A1 mRNA]

PMID:22975028 PMID:29521512

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

G

prolactin receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PRLR mRNA

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

G

prominin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PROM1 mRNA

NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527

G

serine protease 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PRSS8 mRNA

NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815

G

phosphoserine aminotransferase 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PSAT1 mRNA
beta-Naphthoflavone results in increased expression of PSAT1 mRNA

PMID:18164116 PMID:32858204

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

proteasome 20S subunit beta 5

increases activity
increases expression

beta-Naphthoflavone results in increased activity of PSMB5 protein
beta-Naphthoflavone results in increased expression of PSMB5 protein

NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440

G

proteasome 26S subunit, ATPase 1

increases expression

beta-Naphthoflavone results in increased expression of PSMC1 mRNA

NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123

G

proteasome 26S subunit, ATPase 2

increases expression

beta-Naphthoflavone results in increased expression of PSMC2 mRNA

NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185

G

proteasome 26S subunit, ATPase 4

increases expression

beta-Naphthoflavone results in increased expression of PSMC4 mRNA

NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494

G

proteasome 26S subunit, non-ATPase 13

increases expression

beta-Naphthoflavone results in increased expression of PSMD13 mRNA

NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905

G

prostaglandin D2 synthase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGDS mRNA

NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833

G

prostaglandin F receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PTGFR mRNA

NCBI chr 2:240,731,185...240,766,674
Ensembl chr 2:240,733,375...240,765,650

G

prostaglandin reductase 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of PTGR1 mRNA

NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666

G

prostaglandin-endoperoxide synthase 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of PTGS2 mRNA; beta-Naphthoflavone results in increased expression of PTGS2 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]

PMID:18164116 PMID:20045035 PMID:22687991 PMID:23038005

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

pleiotrophin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTN mRNA

NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456

G

protein tyrosine phosphatase, non-receptor type 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTPN3 mRNA

NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443

G

PTTG1 regulator of sister chromatid separation, securin

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTTG1 mRNA
beta-Naphthoflavone results in decreased expression of PTTG1 mRNA

PMID:18164116 PMID:32858204

NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837

G

quinolinate phosphoribosyltransferase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of QPRT mRNA
beta-Naphthoflavone results in decreased expression of QPRT mRNA

PMID:18164116 PMID:32858204

NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486

G

RAB11 family interacting protein 5

decreases expression

beta-Naphthoflavone results in decreased expression of RAB11FIP5 mRNA

NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741

G

retinoic acid induced 14

decreases expression

beta-Naphthoflavone results in decreased expression of RAI14 mRNA

NCBI chr 2:59,546,284...59,682,687
Ensembl chr 2:59,546,284...59,681,971

G

Rap1 GTPase-activating protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RAP1GAP mRNA

NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253

G

ras related dexamethasone induced 1

increases expression

beta-Naphthoflavone results in increased expression of RASD1 mRNA

NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186

G

RAS-like family 11 member B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RASL11B mRNA

NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152

G

Ras association domain family member 4

decreases expression

beta-Naphthoflavone results in decreased expression of RASSF4 mRNA

NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411

G

RB transcriptional corepressor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RB1 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RNA binding motif protein 33

increases expression

beta-Naphthoflavone results in increased expression of RBM33 mRNA

NCBI chr 4:6,980,807...7,088,334
Ensembl chr 4:6,983,970...7,089,918

G

retinol binding protein 4

increases expression

beta-Naphthoflavone results in increased expression of RBP4 mRNA

NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399

G

regulator of calcineurin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RCAN1 mRNA

NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045

G

regulator of calcineurin 2

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of RCAN2 mRNA]

NCBI chr 9:16,959,478...17,174,823
Ensembl chr 9:16,959,480...17,174,856

G

RCC1 and BTB domain containing protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RCBTB1 mRNA

NCBI chr15:33,319,586...33,362,421
Ensembl chr15:33,319,586...33,365,302

G

RCC1 and BTB domain containing protein 2

increases expression

beta-Naphthoflavone results in increased expression of RCBTB2 mRNA

NCBI chr15:48,319,809...48,364,441
Ensembl chr15:48,323,866...48,383,750

G

retinol dehydrogenase 11

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of RDH11 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of RDH11 mRNA]

NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252

G

receptor accessory protein 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of REEP6 mRNA

NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597

G

regenerating family member 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of REG4 mRNA

NCBI chr 2:185,818,946...185,833,252
Ensembl chr 2:185,821,210...185,833,353

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

beta-Naphthoflavone inhibits the reaction [Triclosan results in decreased expression of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RELB proto-oncogene, NF-kB subunit

increases expression

beta-Naphthoflavone results in increased expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

regulator of cell cycle

decreases expression

beta-Naphthoflavone results in decreased expression of RGCC mRNA

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

G

regucalcin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RGN mRNA

NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450

G

regulator of G-protein signaling 1

decreases expression

beta-Naphthoflavone results in decreased expression of RGS1 mRNA

NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984

G

regulator of G-protein signaling 10

increases expression

beta-Naphthoflavone results in increased expression of RGS10 mRNA

NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697

G

regulator of G-protein signaling 12

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RGS12 mRNA

NCBI chr14:75,715,925...75,824,012
Ensembl chr14:75,715,934...75,794,596

G

regulator of G-protein signaling 16

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RGS16 mRNA

NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857

G

regulator of G-protein signaling 20

increases expression

beta-Naphthoflavone results in increased expression of RGS20 mRNA

NCBI chr 5:14,484,436...14,614,317
Ensembl chr 5:14,534,775...14,614,084

G

regulator of G-protein signaling 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RGS4 mRNA

NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068

G

regulator of G-protein signaling 9

increases expression

beta-Naphthoflavone results in increased expression of RGS9 mRNA

NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892

G

Rh family B glycoprotein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RHBG mRNA

NCBI chr 2:173,704,852...173,717,380
Ensembl chr 2:173,704,562...173,717,321

G

Rho-related BTB domain containing 1

decreases expression

beta-Naphthoflavone results in decreased expression of RHOBTB1 mRNA

NCBI chr20:19,327,142...19,456,121
Ensembl chr20:19,327,155...19,403,012

G

receptor-interacting serine-threonine kinase 2

decreases expression

beta-Naphthoflavone results in decreased expression of RIPK2 mRNA

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

G

Ras-like without CAAX 1

increases expression

beta-Naphthoflavone results in increased expression of RIT1 mRNA

NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455

G

ribonuclease T2

decreases expression

beta-Naphthoflavone results in decreased expression of RNASET2 mRNA

NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147

G

ring finger protein 24

increases expression

beta-Naphthoflavone results in increased expression of RNF24 mRNA

NCBI chr 3:118,520,459...118,575,213
Ensembl chr 3:118,525,349...118,541,080

G

ribosomal protein lateral stalk subunit P0

decreases expression
increases expression

beta-Naphthoflavone results in decreased expression of RPLP0 mRNA
beta-Naphthoflavone results in increased expression of RPLP0 mRNA

PMID:12883083 PMID:23994337

NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632

G

ribosomal protein S6 kinase A2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RPS6KA2 mRNA

NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739

G

ribosomal protein S6 kinase A5

decreases expression

beta-Naphthoflavone results in decreased expression of RPS6KA5 mRNA

NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224

G

ribosomal RNA processing 1B

increases expression

beta-Naphthoflavone results in increased expression of RRP1B mRNA

NCBI chr20:10,123,111...10,148,704
Ensembl chr20:10,123,125...10,147,928

G

rhotekin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RTKN mRNA

NCBI chr 4:115,640,813...115,657,952
Ensembl chr 4:115,640,774...115,657,952

G

reticulon 4

decreases expression

beta-Naphthoflavone results in decreased expression of RTN4 mRNA

NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686

G

RUNX family transcription factor 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RUNX3 mRNA

NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156

G

retinoid X receptor gamma

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RXRG mRNA

NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167

G

S100 calcium-binding protein A4

increases expression

beta-Naphthoflavone results in increased expression of S100A4 mRNA

NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254

G

S100 calcium binding protein A8

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of S100A8 mRNA
beta-Naphthoflavone results in increased expression of S100A8 mRNA

PMID:18164116 PMID:32151702 PMID:32858204

NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643

G

S100 calcium binding protein A9

increases expression

beta-Naphthoflavone results in increased expression of S100A9 mRNA

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

G

sphingosine-1-phosphate receptor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of S1PR1 mRNA

NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681

G

stabilizer of axonemal microtubules 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SAXO4 mRNA

NCBI chr 1:207,113,807...207,122,378
Ensembl chr 1:207,113,809...207,122,358

G

secretory carrier membrane protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCAMP1 mRNA

NCBI chr 2:25,433,958...25,516,734
Ensembl chr 2:25,433,959...25,516,673

G

stearoyl-CoA desaturase

decreases expression

beta-Naphthoflavone results in decreased expression of SCD1 mRNA
beta-Naphthoflavone results in decreased expression of SCD mRNA

PMID:28973660 PMID:31225620

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

schwannomin interacting protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCHIP1 mRNA

NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:152,126,953...152,888,585

G

sodium voltage-gated channel beta subunit 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCN4B mRNA

NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292

G

secernin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SCRN1 mRNA

NCBI chr 4:83,632,125...83,694,225
Ensembl chr 4:83,632,131...83,693,852

G

secretin receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCTR mRNA

NCBI chr13:31,127,781...31,190,162
Ensembl chr13:31,127,858...31,180,189

G

syndecan 1

decreases expression

beta-Naphthoflavone results in decreased expression of SDC1 mRNA

NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264

G

serine dehydratase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SDS mRNA

NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203

G

semaphorin 3B

decreases expression

beta-Naphthoflavone results in decreased expression of SEMA3B mRNA

NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919

G

semaphorin 6B

increases expression

beta-Naphthoflavone results in increased expression of SEMA6B mRNA

NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521

G

septin 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SEPTIN4 mRNA

NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768

G

serine (or cysteine) peptidase inhibitor, clade A, member 3N

decreases expression

beta-Naphthoflavone results in decreased expression of SERPINA3 mRNA

NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433

G

serpin family A member 4

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SERPINA4 mRNA
beta-Naphthoflavone results in decreased expression of SERPINA4 mRNA

PMID:18164116 PMID:19737606

NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082

G

serpin family A member 7

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of SERPINA7 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of SERPINA7 mRNA; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SERPINA7 mRNA]

PMID:19737545 PMID:19737606 PMID:22234961

NCBI chr X:102,663,242...102,722,319
Ensembl chr X:102,663,405...102,669,040

G

serpin family B member 1A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINB1A mRNA

NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102

G

serpin family E member 1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of SERPINE1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA]

PMID:18164116 PMID:19737606 PMID:20045035 PMID:21295105 PMID:22687991

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

stratifin

increases expression

beta-Naphthoflavone results in increased expression of SFN mRNA

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

SWI5-dependent homologous recombination repair protein 1

increases expression

beta-Naphthoflavone results in increased expression of SFR1 mRNA

NCBI chr 1:246,619,235...246,623,250
Ensembl chr 1:246,597,044...246,623,250

G

secreted frizzled-related protein 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SFRP1 mRNA
beta-Naphthoflavone results in decreased expression of SFRP1 mRNA

PMID:18164116 PMID:32858204

NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286

G

sideroflexin 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SFXN3 mRNA

NCBI chr 1:243,907,958...243,917,065
Ensembl chr 1:243,907,751...243,917,073

G

serum/glucocorticoid regulated kinase 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of SGK2 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SGK2 mRNA

PMID:18164116 PMID:19737606

NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480

G

SH2 domain containing 5

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of SH2D5 mRNA
beta-Naphthoflavone results in decreased expression of SH2D5 mRNA

PMID:19737606 PMID:32858204

NCBI chr 5:150,469,738...150,480,615
Ensembl chr 5:150,467,728...150,479,955

G

SLAM family member 7

decreases expression

beta-Naphthoflavone results in decreased expression of SLAMF7 mRNA

NCBI chr13:84,135,656...84,154,528
Ensembl chr13:84,136,899...84,154,105

G

solute carrier family 10 member 1

decreases expression

beta-Naphthoflavone results in decreased expression of SLC10A1 mRNA

NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 13 member 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC13A5 mRNA

NCBI chr10:56,866,249...56,891,189
Ensembl chr10:56,866,249...56,890,945

G

solute carrier family 16 member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC16A1 mRNA

NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611

G

solute carrier family 16 member 10

decreases expression

beta-Naphthoflavone results in decreased expression of SLC16A10 mRNA

NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839

G

solute carrier family 16, member 4

decreases expression

beta-Naphthoflavone results in decreased expression of SLC16A4 mRNA

NCBI chr 2:194,911,075...194,933,162
Ensembl chr 2:194,911,236...194,933,117

G

solute carrier family 16, member 6

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC16A6 mRNA
beta-Naphthoflavone results in increased expression of SLC16A6 mRNA

PMID:18164116 PMID:19737606

NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779

G

solute carrier family 17 member 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC17A6 mRNA

NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542

G

solute carrier family 19 member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC19A2 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC19A2 mRNA

NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172

G

solute carrier family 19 member 3

decreases expression

beta-Naphthoflavone results in decreased expression of SLC19A3 mRNA

NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337

G

solute carrier family 1 member 4

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of SLC1A4 mRNA

NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418

G

solute carrier family 1 member 5

increases expression

beta-Naphthoflavone results in increased expression of SLC1A5 mRNA

NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952

G

solute carrier family 20 member 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC20A1 mRNA
beta-Naphthoflavone results in increased expression of SLC20A1 mRNA

PMID:18164116 PMID:19737606

NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051

G

solute carrier family 22 member 1

decreases expression

beta-Naphthoflavone results in decreased expression of SLC22A1 mRNA

NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678

G

solute carrier family 25 member 29

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC25A29 mRNA

NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940

G

solute carrier family 25 member 36

increases expression

beta-Naphthoflavone results in increased expression of SLC25A36 mRNA

NCBI chr 8:97,659,848...97,693,735
Ensembl chr 8:97,662,127...97,693,703

G

solute carrier family 27 member 2

increases expression

beta-Naphthoflavone results in increased expression of SLC27A2 mRNA

NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208

G

solute carrier family 2 member 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC2A1 protein
beta-Naphthoflavone results in decreased expression of SLC2A1 mRNA

PMID:28903497 PMID:29521512 PMID:32858204

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 5

decreases expression

beta-Naphthoflavone results in decreased expression of SLC2A5 mRNA

NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106

G

solute carrier family 2 member 8

increases expression

beta-Naphthoflavone results in increased expression of SLC2A8 mRNA

NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:16,274,925...16,284,464

G

solute carrier family 30, member 10

decreases expression

beta-Naphthoflavone results in decreased expression of SLC30A10 mRNA

NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103

G

solute carrier family 30 member 2

decreases expression

beta-Naphthoflavone results in decreased expression of SLC30A2 mRNA

NCBI chr 5:146,559,733...146,571,957
Ensembl chr 5:146,559,733...146,571,956

G

solute carrier family 34 member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC34A2 mRNA

NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436

G

solute carrier family 35 member B2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC35B2 mRNA

NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234

G

solute carrier family 38, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC38A2 mRNA

NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436

G

solute carrier family 38, member 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC38A4 mRNA

NCBI chr 7:128,142,866...128,203,000
Ensembl chr 7:128,144,807...128,202,995

G

solute carrier family 39 member 5

decreases expression

beta-Naphthoflavone results in decreased expression of SLC39A5 mRNA

NCBI chr 7:822,873...830,865
Ensembl chr 7:824,818...830,242

G

solute carrier family 39 member 8

decreases expression

beta-Naphthoflavone results in decreased expression of SLC39A8 mRNA

NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129

G

solute carrier family 3 member 2

increases expression

beta-Naphthoflavone results in increased expression of SLC3A2 mRNA

NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931

G

solute carrier family 43 member 2

decreases expression

beta-Naphthoflavone results in decreased expression of SLC43A2 mRNA

NCBI chr10:60,375,462...60,420,838
Ensembl chr10:60,376,559...60,418,244

G

solute carrier family 44, member 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC44A4 mRNA

NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215

G

solute carrier family 48 member 1

increases expression

beta-Naphthoflavone results in increased expression of SLC48A1 mRNA

NCBI chr 7:128,915,136...128,923,929
Ensembl chr 7:128,915,195...128,923,024

G

solute carrier family 4 member 1 (Diego blood group)

decreases expression

beta-Naphthoflavone results in decreased expression of SLC4A1 mRNA

NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117

G

solute carrier family 66 member 2

increases expression

beta-Naphthoflavone results in increased expression of SLC66A2 mRNA

NCBI chr18:73,702,472...73,739,678
Ensembl chr18:73,702,564...73,739,676

G

solute carrier family 66 member 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC66A3 mRNA

NCBI chr 6:39,774,801...39,786,554
Ensembl chr 6:39,774,808...39,786,303

G

solute carrier family 6 member 20a

increases expression

beta-Naphthoflavone results in increased expression of SLC6A20 mRNA

NCBI chr 8:123,282,325...123,322,609
Ensembl chr 8:123,281,472...123,322,573

G

solute carrier family 6 member 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC6A6 mRNA

NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875

G

solute carrier family 7 member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC7A1 mRNA

NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849

G

solute carrier family 7 member 5

increases expression

beta-Naphthoflavone results in increased expression of SLC7A5 mRNA

NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823

G

solute carrier organic anion transporter family, member 1a4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLCO1A4 mRNA

NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573

G

solute carrier organic anion transporter family, member 2b1

increases expression

beta-Naphthoflavone results in increased expression of SLCO2B1 mRNA

NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353

G

solute carrier organic anion transporter family, member 3a1

increases expression

beta-Naphthoflavone results in increased expression of SLCO3A1 mRNA

NCBI chr 1:128,106,232...128,388,043
Ensembl chr 1:128,106,228...128,387,925

G

SMAD family member 6

decreases expression

beta-Naphthoflavone results in decreased expression of SMAD6 mRNA

NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763

G

synuclein alpha

decreases expression

beta-Naphthoflavone results in decreased expression of SNCA mRNA

NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262

G

SNF related kinase

increases expression

beta-Naphthoflavone results in increased expression of SNRK mRNA

NCBI chr 8:121,779,704...121,833,949
Ensembl chr 8:121,793,302...121,832,323

G

small nuclear ribonucleoprotein polypeptide A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SNRPA mRNA

NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538

G

suppressor of cytokine signaling 2

increases expression

beta-Naphthoflavone results in increased expression of SOCS2 mRNA

NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548

G

superoxide dismutase 2

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of SOD2 mRNA
beta-Naphthoflavone results in decreased expression of SOD2 mRNA

PMID:32151702 PMID:32858204

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

sortilin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SORT1 mRNA

NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354

G

sperm associated antigen 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SPAG5 mRNA

NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745

G

sperm associated antigen 8

decreases expression

beta-Naphthoflavone results in decreased expression of SPAG8 mRNA

NCBI chr 5:57,901,681...57,903,894
Ensembl chr 5:57,901,682...57,903,894

G

spindlin 1

increases expression

beta-Naphthoflavone results in increased expression of SPIN1 mRNA

NCBI chr17:14,055,685...14,105,366
Ensembl chr17:14,055,689...14,105,411

G

serine peptidase inhibitor, Kazal type 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SPINK1 mRNA

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

spondin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SPON1 mRNA

NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226

G

secreted phosphoprotein 1

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of SPP1 mRNA
beta-Naphthoflavone results in decreased expression of SPP1 mRNA

PMID:19737545 PMID:32858204

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

small proline-rich protein 2A2

increases expression

beta-Naphthoflavone results in increased expression of SPRR2E mRNA

NCBI chr 2:177,719,576...177,719,845
Ensembl chr 2:177,719,576...177,719,845

G

small proline-rich protein 2D

increases expression

beta-Naphthoflavone results in increased expression of SPRR2D mRNA

PMID:32151702 PMID:32858204

NCBI chr 2:177,870,082...177,870,679
Ensembl chr 2:177,870,434...177,870,679

G

small proline rich protein 2F

increases expression

beta-Naphthoflavone results in increased expression of SPRR2F mRNA

NCBI chr 2:177,989,974...177,990,204
Ensembl chr 2:177,989,974...177,990,204

G

sprouty RTK signaling antagonist 1

decreases expression

beta-Naphthoflavone results in decreased expression of SPRY1 mRNA

NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189

G

serine palmitoyltransferase, long chain base subunit 3

decreases expression

beta-Naphthoflavone results in decreased expression of SPTLC3 mRNA

NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010

G

squalene epoxidase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SQLE mRNA
beta-Naphthoflavone results in decreased expression of SQLE mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SQLE mRNA]

PMID:18164116 PMID:22234961

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

sequestosome 1

increases expression

beta-Naphthoflavone results in increased expression of SQSTM1 mRNA

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

SRC proto-oncogene, non-receptor tyrosine kinase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SRC mRNA

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

G

steroid 5 alpha-reductase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SRD5A1 mRNA

NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461

G

sterol regulatory element binding transcription factor 1

decreases expression

beta-Naphthoflavone results in decreased expression of SREBF1 mRNA

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

G

signal recognition particle 19

increases expression

beta-Naphthoflavone results in increased expression of SRP19 mRNA

NCBI chr18:25,931,734...25,937,974
Ensembl chr18:25,931,589...25,938,017

G

SRP receptor subunit alpha

increases expression

beta-Naphthoflavone results in increased expression of SRPRA mRNA

NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470

G

sushi-repeat-containing protein, X-linked

decreases expression
increases expression

beta-Naphthoflavone results in decreased expression of SRPX mRNA
beta-Naphthoflavone results in increased expression of SRPX mRNA

PMID:19737606 PMID:32858204

NCBI chr X:12,676,984...12,751,296
Ensembl chr X:12,566,645...12,747,882

G

sulfiredoxin 1

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of SRXN1 mRNA
beta-Naphthoflavone results in increased expression of SRXN1 mRNA

PMID:19737545 PMID:32858204

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

slingshot protein phosphatase 1

increases expression

beta-Naphthoflavone results in increased expression of SSH1 mRNA

NCBI chr12:42,621,127...42,683,262
Ensembl chr12:42,621,135...42,683,274

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ST3GAL2 mRNA

NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

increases expression

beta-Naphthoflavone results in increased expression of ST3GAL6 mRNA

NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ST6GALNAC2 mRNA

NCBI chr10:101,910,220...101,928,412
Ensembl chr10:101,909,971...101,915,008
Ensembl chr10:101,909,971...101,915,008

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

increases expression

beta-Naphthoflavone results in increased expression of ST6GALNAC4 mRNA

NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ST8SIA1 mRNA

NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708

G

StAR-related lipid transfer domain containing 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of STARD6 mRNA

NCBI chr18:64,089,618...64,118,528
Ensembl chr18:64,089,471...64,107,099

G

signal transducer and activator of transcription 5A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of STAT5A mRNA

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

G

STEAP4 metalloreductase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of STEAP4 mRNA

NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859

G

stathmin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of STMN1 mRNA

NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154

G

succinate-CoA ligase GDP/ADP-forming subunit alpha

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SUCLG1 mRNA

NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600

G

sulfotransferase family 1A member 1

decreases expression

beta-Naphthoflavone results in decreased expression of SULT1A1 mRNA

NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562

G

sulfotransferase family 1C member 2A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SULT1C2 mRNA

NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734

G

sulfotransferase family 1E member 1

increases expression

beta-Naphthoflavone results in increased expression of SULT1E1 mRNA

NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275

G

sulfotransferase family 2A member 1

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of SULT2A1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SULT2A1 mRNA

PMID:9566755 PMID:18164116

NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134

G

sulfotransferase family 2B member 1

increases expression

beta-Naphthoflavone results in increased expression of SULT2B1 mRNA

NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295

G

sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

decreases expression

beta-Naphthoflavone results in decreased expression of SVEP1 mRNA

NCBI chr 5:72,811,200...72,988,185
Ensembl chr 5:72,811,410...72,988,525

G

synapse defective Rho GTPase homolog 1

decreases expression

beta-Naphthoflavone results in decreased expression of SYDE1 mRNA

NCBI chr 7:11,032,931...11,038,917
Ensembl chr 7:11,032,898...11,039,869

G

synergin, gamma

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SYNRG mRNA

NCBI chr10:68,848,828...68,931,252
Ensembl chr10:68,849,642...68,931,250

G

synaptotagmin 7

decreases expression

beta-Naphthoflavone results in decreased expression of SYT7 mRNA

NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026

G

transgelin

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of TAGLN mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TAGLN mRNA

PMID:17175557 PMID:18164116 PMID:32858204

NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668

G

transaldolase 1

increases expression

beta-Naphthoflavone results in increased expression of TALDO1 mRNA

NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974

G

tubulin folding cofactor E-like

increases expression

beta-Naphthoflavone results in increased expression of TBCEL mRNA

NCBI chr 8:42,795,648...42,854,552
Ensembl chr 8:42,796,730...42,854,552

G

thromboxane A synthase 1

increases expression

beta-Naphthoflavone results in increased expression of TBXAS1 mRNA

NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096

G

transcription factor 19

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TCF19 mRNA

NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271

G

tryptophan 2,3-dioxygenase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of TDO2 mRNA

NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511

G

tyrosyl-DNA phosphodiesterase 2

increases expression

beta-Naphthoflavone results in increased expression of TDP2 mRNA

NCBI chr17:40,228,943...40,240,337
Ensembl chr17:40,228,947...40,240,313

G

TEF transcription factor, PAR bZIP family member

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TEF mRNA

NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783

G

teneurin transmembrane protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TENM2 mRNA

NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597

G

terminal nucleotidyltransferase 5A

decreases expression

beta-Naphthoflavone results in decreased expression of TENT5A mRNA

NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045

G

transcription factor Dp-2

decreases expression

beta-Naphthoflavone results in decreased expression of TFDP2 mRNA

NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682

G

trefoil factor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TFF1 mRNA

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

tissue factor pathway inhibitor

decreases expression

beta-Naphthoflavone results in decreased expression of TFPI mRNA

NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880

G

transforming growth factor, beta 1

multiple interactions
decreases expression

alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of TGFB1 mRNA]

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

transforming growth factor beta receptor 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TGFBR3 mRNA

NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341

G

transglutaminase 1

affects expression

beta-Naphthoflavone affects the expression of TGM1 protein

NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523

G

transglutaminase 2

decreases expression

beta-Naphthoflavone results in decreased expression of TGM2 mRNA

NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981

G

thrombospondin 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of THBS1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of THBS1 mRNA

PMID:18164116 PMID:19737545

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

thyroid hormone responsive

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of THRSP mRNA

NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075

G

Thy-1 cell surface antigen

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of THY1 mRNA

NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659

G

TIMP metallopeptidase inhibitor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TIMP1 mRNA

PMID:18164116 PMID:20045035

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

TIMP metallopeptidase inhibitor 2

increases expression

beta-Naphthoflavone results in increased expression of TIMP2 mRNA

NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611

G

TCDD-inducible poly(ADP-ribose) polymerase

increases expression

beta-Naphthoflavone results in increased expression of TIPARP mRNA

PMID:23994337 PMID:32858204

NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327

G

triokinase and FMN cyclase

decreases expression

beta-Naphthoflavone results in decreased expression of TKFC mRNA

NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737

G

toll-like receptor 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TLR2 mRNA

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

toll-like receptor 8

increases expression

beta-Naphthoflavone results in increased expression of TLR8 mRNA

NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549

G

transmembrane 4 L six family member 1

decreases expression

beta-Naphthoflavone results in decreased expression of TM4SF1 mRNA

NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146

G

transmembrane 6 superfamily member 2

increases expression

beta-Naphthoflavone results in increased expression of TM6SF2 mRNA

NCBI chr16:19,344,218...19,351,431
Ensembl chr16:19,344,222...19,351,431

G

transmembrane p24 trafficking protein 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TMED3 mRNA

NCBI chr 8:90,241,516...90,249,429
Ensembl chr 8:90,241,516...90,249,346

G

transmembrane protein 147

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TMEM147 mRNA

NCBI chr 1:85,977,028...85,978,848
Ensembl chr 1:85,977,025...85,978,868

G

transmembrane protein 184C

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TMEM184C mRNA

NCBI chr19:30,345,183...30,361,275
Ensembl chr19:30,345,290...30,361,269

G

transmembrane protein 40

increases expression

beta-Naphthoflavone results in increased expression of TMEM40 mRNA

NCBI chr 4:148,791,509...148,819,287
Ensembl chr 4:148,791,505...148,823,665

G

transmembrane protein 70

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TMEM70 protein

PMID:27914986 PMID:28903497

NCBI chr 5:2,637,102...2,654,729
Ensembl chr 5:2,637,102...2,654,729

G

transmembrane serine protease 11F

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of TMPRSS11F mRNA

NCBI chr14:21,492,896...21,534,792
Ensembl chr14:21,429,418...21,534,809

G

thymosin beta 15B2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TMSB15B2 mRNA

NCBI chr X:100,298,705...100,300,820
Ensembl chr X:100,298,514...100,300,886

G

tenascin C

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNC mRNA

NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624

G

tumor necrosis factor

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]
beta-Naphthoflavone results in increased expression of TNF mRNA

PMID:21295105 PMID:32151702

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 2

increases expression

beta-Naphthoflavone results in increased expression of TNFAIP2 mRNA

NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914

G

TNF alpha induced protein 6

decreases expression

beta-Naphthoflavone results in decreased expression of TNFAIP6 mRNA

NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649

G

TNF receptor superfamily member 12A

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF12A mRNA
beta-Naphthoflavone results in increased expression of TNFRSF12A mRNA

PMID:18164116 PMID:19737606

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

G

TNF receptor superfamily member 19

decreases expression

beta-Naphthoflavone results in decreased expression of TNFRSF19 mRNA

NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795

G

TNF receptor superfamily member 1A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein]

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

G

TNF receptor superfamily member 9

decreases expression

beta-Naphthoflavone results in decreased expression of TNFRSF9 mRNA

NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000

G

troponin C1, slow skeletal and cardiac type

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of TNNC1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNNC1 mRNA

PMID:18164116 PMID:19737606

NCBI chr16:6,400,801...6,405,634
Ensembl chr16:6,402,171...6,405,634

G

tensin 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TNS4 mRNA

NCBI chr10:84,021,965...84,041,346
Ensembl chr10:84,021,966...84,041,346

G

target of myb1 like 2 membrane trafficking protein

decreases expression

beta-Naphthoflavone results in decreased expression of TOM1L2 mRNA

NCBI chr10:45,036,034...45,158,168
Ensembl chr10:45,036,035...45,158,032

G

DNA topoisomerase II alpha

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TOP2A mRNA
beta-Naphthoflavone results in decreased expression of TOP2A mRNA

PMID:18164116 PMID:32858204

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

torsin family 3, member A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TOR3A mRNA

NCBI chr13:68,769,893...68,798,738
Ensembl chr13:68,769,605...68,798,475

G

tumor protein p53

multiple interactions

[beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tubulin polymerization-promoting protein family member 3

decreases expression

beta-Naphthoflavone results in decreased expression of TPPP3 mRNA

NCBI chr19:33,345,897...33,349,610
Ensembl chr19:33,345,898...33,349,577

G

TNFRSF1A-associated via death domain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein]

NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638

G

triggering receptor expressed on myeloid cells-like 2

decreases expression

beta-Naphthoflavone results in decreased expression of TREML2 mRNA

NCBI chr 9:12,694,453...12,705,379
Ensembl chr 9:12,694,697...12,705,324

G

tribbles pseudokinase 3

increases expression

beta-Naphthoflavone results in increased expression of TRIB3 mRNA

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

transient receptor potential cation channel, subfamily V, member 2

increases expression

beta-Naphthoflavone results in increased expression of TRPV2 mRNA

NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260

G

transient receptor potential cation channel, subfamily V, member 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRPV5 mRNA

NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745

G

tsukushi, small leucine rich proteoglycan

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TSKU mRNA

NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588

G

tetraspanin 10

decreases expression

beta-Naphthoflavone results in decreased expression of TSPAN10 mRNA

NCBI chr10:105,715,803...105,721,503
Ensembl chr10:105,715,961...105,719,813

G

tetraspanin 7

increases expression

beta-Naphthoflavone results in increased expression of TSPAN7 mRNA

NCBI chr X:12,208,783...12,306,092
Ensembl chr X:12,208,783...12,306,131

G

tetraspanin 8

increases expression

beta-Naphthoflavone results in increased expression of TSPAN8 mRNA

NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356

G

tetraspanin 9

decreases expression

beta-Naphthoflavone results in decreased expression of TSPAN9 mRNA

NCBI chr 4:160,813,879...160,995,574
Ensembl chr 4:160,813,879...160,995,501

G

tubulin, alpha 1A

decreases expression

beta-Naphthoflavone results in decreased expression of TUBA1A mRNA

NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186

G

tubulin, beta 5 class I

increases expression

beta-Naphthoflavone results in increased expression of TUBB mRNA

NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940

G

tubulin, beta 6 class V

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TUBB6 mRNA

NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418

G

thioredoxin-like 1

increases expression

beta-Naphthoflavone results in increased expression of TXNL1 mRNA

NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266

G

thioredoxin-like 4A

increases expression

beta-Naphthoflavone results in increased expression of TXNL4A mRNA

NCBI chr18:73,659,107...73,674,893
Ensembl chr18:73,659,107...73,674,893

G

thioredoxin reductase 1

increases expression

beta-Naphthoflavone results in increased expression of TXNRD1 mRNA

PMID:12949356 PMID:19737606 PMID:32858204

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

thymidylate synthetase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TYMS mRNA

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

TYRO3 protein tyrosine kinase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TYRO3 mRNA

NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142

G

UBA domain containing 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of UBAC1 mRNA

NCBI chr 3:8,825,444...8,848,055
Ensembl chr 3:8,825,447...8,848,028

G

ubiquitin-associated protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UBAP1 mRNA

NCBI chr 5:56,520,722...56,561,153
Ensembl chr 5:56,520,743...56,561,152

G

ubiquitin C

increases expression

beta-Naphthoflavone results in increased expression of UBC mRNA

NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925

G

ubiquitin D

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UBD mRNA

NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639

G

ubiquitin-conjugating enzyme E2C

decreases expression

beta-Naphthoflavone results in decreased expression of UBE2C mRNA

NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339

G

ubiquitin-conjugating enzyme E2E 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of UBE2E2 protein

NCBI chr15:6,980,241...7,257,912
Ensembl chr15:6,980,474...7,257,532

G

ubiquitin-conjugating enzyme E2L 3

multiple interactions
increases expression

AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of UBE2L3 mRNA]; Dactinomycin inhibits the reaction [beta-Naphthoflavone results in increased expression of UBE2L3 mRNA]; UBE2L3 protein affects the reaction [beta-Naphthoflavone results in decreased expression of FOS protein]

NCBI chr11:83,797,722...83,838,862
Ensembl chr11:83,797,722...83,838,862

G

ubiquitin-conjugating enzyme E2Z

increases expression

beta-Naphthoflavone results in increased expression of UBE2Z mRNA

NCBI chr10:80,997,816...81,016,936
Ensembl chr10:80,997,817...81,016,936

G

uridine-cytidine kinase 2

decreases expression

beta-Naphthoflavone results in decreased expression of UCK2 mRNA

NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352

G

UDP-glucose ceramide glucosyltransferase

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of UGCG mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of UGCG mRNA]

NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393

G

UDP-glucose glycoprotein glucosyltransferase 1

decreases expression

beta-Naphthoflavone results in decreased expression of UGGT1 mRNA

NCBI chr 9:38,355,229...38,468,473
Ensembl chr 9:38,359,089...38,468,467

G

UDP glucuronosyltransferase family 1 member A1

multiple interactions
increases activity
increases expression

beta-Naphthoflavone promotes the reaction [[AHR protein binds to UGT1A1 enhancer] which results in increased expression of UGT1A1 mRNA]; beta-Naphthoflavone results in increased expression of and results in increased activity of UGT1A1 protein
beta-Naphthoflavone results in increased activity of UGT1A1 protein
beta-Naphthoflavone results in increased expression of UGT1A1 mRNA; beta-Naphthoflavone results in increased expression of UGT1A1 protein

PMID:12566446 PMID:16399344 PMID:17917264 PMID:19118567 PMID:19144771 More...

NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase 1 family, polypeptide A2

increases expression

beta-Naphthoflavone results in increased expression of UGT1A2 mRNA; beta-Naphthoflavone results in increased expression of UGT1A3 mRNA

PMID:19118567 PMID:28601433

NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glycosyltransferase 1 family, polypeptide A3

increases expression

beta-Naphthoflavone results in increased expression of UGT1A5 mRNA

PMID:19118567 PMID:28601433

NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A5

increases expression

beta-Naphthoflavone results in increased expression of UGT1A4 mRNA
beta-Naphthoflavone results in increased expression of UGT1A5 mRNA

PMID:19118567 PMID:19144771

NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A6

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of UGT1A6 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA
beta-Naphthoflavone promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]

PMID:7646562 PMID:12883083 PMID:12948865 PMID:17917264 PMID:18094037 More...

NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A9

increases expression

beta-Naphthoflavone results in increased expression of UGT1A9 mRNA

PMID:17917264 PMID:19118567 PMID:19144771

NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 2 member A3

decreases expression

beta-Naphthoflavone results in decreased expression of UGT2A3 mRNA

NCBI chr14:20,572,793...20,590,795
Ensembl chr14:20,572,808...20,590,729

G

UDP glycosyltransferase 2 family, polypeptide B

increases expression

beta-Naphthoflavone results in increased expression of UGT2B mRNA

NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776

G

unk like zinc finger

increases expression

beta-Naphthoflavone results in increased expression of UNKL mRNA

NCBI chr10:14,206,125...14,252,226
Ensembl chr10:14,206,189...14,252,225

G

UTP25 small subunit processome component

increases expression

beta-Naphthoflavone results in increased expression of UTP25 mRNA

NCBI chr13:104,630,390...104,651,681
Ensembl chr13:104,630,391...104,651,662

G

utrophin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UTRN mRNA

NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313

G

UV radiation resistance associated

increases expression

beta-Naphthoflavone results in increased expression of UVRAG mRNA

NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136

G

vascular cell adhesion molecule 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of VCAM1 mRNA

NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958

G

ventricular zone expressed PH domain-containing 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VEPH1 mRNA

NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266

G

villin 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of VIL1 mRNA

NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858

G

vimentin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VIM mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of VIM mRNA

PMID:18164116 PMID:19737545

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

G

vanin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VNN1 mRNA

NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395

G

von Willebrand factor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VWF mRNA

NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539

G

WD repeat domain 45

increases expression

beta-Naphthoflavone results in increased expression of WDR45 mRNA

NCBI chr X:14,776,280...14,782,202
Ensembl chr X:14,776,293...14,782,202

G

wolframin ER transmembrane glycoprotein

decreases expression

beta-Naphthoflavone results in decreased expression of WFS1 mRNA

NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602

G

WNK lysine deficient protein kinase 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of WNK4 mRNA

NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829

G

Wnt family member 2B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of WNT2B mRNA

NCBI chr 2:192,454,226...192,468,599
Ensembl chr 2:192,453,824...192,470,308

G

Wnt family member 5A

increases expression

beta-Naphthoflavone results in increased expression of WNT5A mRNA

NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234

G

WD repeat and SOCS box-containing 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of WSB1 mRNA

NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019

G

X-box binding protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of XBP1 mRNA

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

G

xanthine dehydrogenase

increases expression

beta-Naphthoflavone results in increased expression of XDH mRNA

NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268

G

X-prolyl aminopeptidase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of XPNPEP2 mRNA

NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223

G

yippee-like 1

increases expression

beta-Naphthoflavone results in increased expression of YPEL1 mRNA

NCBI chr11:83,921,799...83,936,409

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

increases expression

beta-Naphthoflavone results in increased expression of YWHAE mRNA

NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589

G

zinc finger and BTB domain containing 16

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZBTB16 mRNA

NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011

G

zinc finger CCCH-type containing, antiviral 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZC3HAV1 mRNA

NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428

G

zinc finger DHHC-type palmitoyltransferase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZDHHC2 mRNA

NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060

G

zinc finger protein 219

affects expression

beta-Naphthoflavone affects the expression of ZFP219 mRNA

NCBI chr15:24,695,831...24,710,039
Ensembl chr15:24,695,837...24,710,030

G

zinc finger protein 354A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZNF354A mRNA

NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068

G

zymogen granule protein 16B

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of SBPL mRNA

NCBI chr10:12,970,888...12,984,170
Ensembl chr10:12,979,020...12,983,572

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19831
role	19807
biological role	19805
pharmacological role	19054
agonist	18597
aryl hydrocarbon receptor agonist	1985
beta-naphthoflavone	1123
Path 2
Term	Annotations
CHEBI ontology	19831
subatomic particle	19829
composite particle	19829
hadron	19829
baryon	19829
nucleon	19829
atomic nucleus	19829
atom	19829
main group element atom	19779
p-block element atom	19779
carbon group element atom	19728
carbon atom	19724
organic molecular entity	19724
organic molecule	19677
organic cyclic compound	19490
organic heterocyclic compound	18852
oxacycle	17838
benzopyran	11965
1-benzopyran	11716
flavonoid	7192
extended flavonoid	1218
beta-naphthoflavone	1123

paths to the root