CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: methylseleninic acid
Accession: CHEBI:77012
browse the term
Definition: An organoselenium compound that is seleninic acid in which the hydrogen attached to selenium is replaced by a methyl group.
Synonyms: exact_synonym: methaneseleninic acid
related_synonym: Formula=CH4O2Se; InChI=1S/CH4O2Se/c1-4(2)3/h1H3,(H,2,3); InChIKey=UEQANLFPOFICBH-UHFFFAOYSA-N; Methylseleninate; SMILES=C[Se](O)=O
xref: CAS:28274-57-9; KEGG:C18902
xref_mesh: MESH:C008493
xref: PMID:21500193; PMID:21519842; PMID:21910718; PMID:22095442; PMID:22128327; PMID:22179721; PMID:22348099; PMID:22640261; PMID:22711297; PMID:22975630; PMID:23470450; PMID:23613334; PMID:23995784; PMID:24001829; PMID:24447148; PMID:24515947; Reaxys:1734752; Wikipedia:Methaneseleninic_Acid
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Abcc4
ATP binding cassette subfamily C member 4
multiple interactions affects expression decreases expression
ISO
AR protein inhibits the reaction [methylselenic acid results in decreased expression of ABCC4 mRNA] methylselenic acid affects the expression of ABCC4 mRNA
CTD
PMID:14617803 PMID:16020662 PMID:18548127
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Acp3
acid phosphatase 3
affects expression
ISO
methylselenic acid affects the expression of ACP3 mRNA
CTD
PMID:14617803
NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
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Acsl3
acyl-CoA synthetase long-chain family member 3
affects expression decreases expression
ISO
methylselenic acid affects the expression of ACSL3 mRNA methylselenic acid results in decreased expression of ACSL3 mRNA
CTD
PMID:14617803 PMID:18548127
NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Acta2
actin alpha 2, smooth muscle
increases expression
ISO
methylselenic acid results in increased expression of ACTA2 mRNA
CTD
PMID:18548127
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actg2
actin gamma 2, smooth muscle
increases expression
ISO
methylselenic acid results in increased expression of ACTG2 mRNA
CTD
PMID:18548127
NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
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Adam22
ADAM metallopeptidase domain 22
increases expression
ISO
methylselenic acid results in increased expression of ADAM22 mRNA
CTD
PMID:18548127
NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
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Add3
adducin 3
increases expression
ISO
methylselenic acid results in increased expression of ADD3 mRNA
CTD
PMID:12517777
NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
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Adgrl3
adhesion G protein-coupled receptor L3
increases expression
ISO
methylselenic acid results in increased expression of ADGRL3 mRNA
CTD
PMID:18548127
NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860
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Ahr
aryl hydrocarbon receptor
increases expression
ISO
methylselenic acid results in increased expression of AHR mRNA
CTD
PMID:18548127
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Akap12
A-kinase anchoring protein 12
increases expression
ISO
methylselenic acid results in increased expression of AKAP12 mRNA
CTD
PMID:18548127
NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
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Akap2
A-kinase anchoring protein 2
increases expression
ISO
methylselenic acid results in increased expression of PALM2AKAP2 mRNA
CTD
PMID:18548127
NCBI chr 5:72,536,986...72,648,524
Ensembl chr 5:72,181,718...72,648,524
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Akr1b1
aldo-keto reductase family 1 member B1
increases expression
ISO
methylselenic acid results in increased expression of AKR1B1 mRNA
CTD
PMID:18548127
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Akt1
AKT serine/threonine kinase 1
decreases response to substance multiple interactions decreases phosphorylation
ISO
AKT1 protein results in decreased susceptibility to methylselenic acid [methylselenic acid results in decreased phosphorylation of AKT1 protein] which results in increased susceptibility to Doxorubicin; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; methylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein]
CTD
PMID:15845651 PMID:17339365
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Akt2
AKT serine/threonine kinase 2
decreases expression
ISO
methylselenic acid results in decreased expression of AKT2 mRNA
CTD
PMID:11830524
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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Alad
aminolevulinate dehydratase
increases expression
ISO
methylselenic acid results in increased expression of ALAD mRNA
CTD
PMID:18548127
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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Alg3
ALG3, alpha-1,3- mannosyltransferase
decreases expression
ISO
methylselenic acid results in decreased expression of ALG3 mRNA
CTD
PMID:18548127
NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912
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Alg8
ALG8, alpha-1,3-glucosyltransferase
decreases expression
ISO
methylselenic acid results in decreased expression of ALG8 mRNA
CTD
PMID:18548127
NCBI chr 1:151,684,344...151,704,310
Ensembl chr 1:151,684,396...151,704,302
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Amt
aminomethyltransferase
increases expression
ISO
methylselenic acid results in increased expression of AMT mRNA
CTD
PMID:18548127
NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126
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Ank2
ankyrin 2
increases expression
ISO
methylselenic acid results in increased expression of ANK2 mRNA
CTD
PMID:18548127
NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
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Ank3
ankyrin 3
decreases expression
ISO
methylselenic acid results in decreased expression of ANK3 mRNA
CTD
PMID:18548127
NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
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Apod
apolipoprotein D
affects expression
ISO
methylselenic acid affects the expression of APOD mRNA
CTD
PMID:14617803
NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
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Ar
androgen receptor
affects response to substance multiple interactions decreases activity decreases expression increases degradation
ISO
AR protein affects the susceptibility to methylselenic acid AR protein inhibits the reaction [methylselenic acid results in decreased expression of ABCC4 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of DHCR24 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of GUCY1A1 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of KLK2 mRNA]; AR protein inhibits the reaction [methylselenic acid results in decreased expression of KLK3 mRNA]; methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to KLK3 promoter]]; Superoxides promotes the reaction [methylselenic acid results in decreased expression of AR protein] methylselenic acid results in decreased activity of AR protein methylselenic acid results in decreased expression of AR mRNA; methylselenic acid results in decreased expression of AR protein methylselenic acid results in increased degradation of AR mRNA; methylselenic acid results in increased degradation of AR protein
CTD
PMID:14617803 PMID:15141018 PMID:16020662 PMID:16648561 PMID:16928829
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arhgef2
Rho/Rac guanine nucleotide exchange factor 2
increases expression
ISO
methylselenic acid results in increased expression of ARHGEF2 mRNA
CTD
PMID:18548127
NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
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Arl4a
ADP-ribosylation factor like GTPase 4A
increases expression
ISO
methylselenic acid results in increased expression of ARL4A mRNA
CTD
PMID:18548127
NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066
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Atf2
activating transcription factor 2
multiple interactions
ISO
methylselenic acid results in increased phosphorylation of and results in increased activity of ATF2 protein
CTD
PMID:11830524
NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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Atf3
activating transcription factor 3
affects expression
ISO
methylselenic acid affects the expression of ATF3 mRNA
CTD
PMID:14617803
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Atf5
activating transcription factor 5
decreases expression
ISO
methylselenic acid results in decreased expression of ATF5 mRNA
CTD
PMID:12517777 PMID:18548127
NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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Atf6
activating transcription factor 6
multiple interactions
ISO
methylselenic acid results in increased cleavage of and results in increased activity of ATF6 protein
CTD
PMID:16205645
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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Atp2a2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
increases expression
ISO
methylselenic acid results in increased expression of ATP2A2 mRNA
CTD
PMID:18548127
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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Atp2b4
ATPase plasma membrane Ca2+ transporting 4
increases expression
ISO
methylselenic acid results in increased expression of ATP2B4 mRNA
CTD
PMID:18548127
NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
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Aurka
aurora kinase A
affects expression decreases expression
ISO
methylselenic acid affects the expression of AURKA mRNA methylselenic acid results in decreased expression of AURKA mRNA
CTD
PMID:12517777 PMID:14617803
NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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B4galt1
beta-1,4-galactosyltransferase 1
affects expression
ISO
methylselenic acid affects the expression of B4GALT1 mRNA
CTD
PMID:14617803
NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
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Bach1
BTB domain and CNC homolog 1
increases expression
ISO
methylselenic acid results in increased expression of BACH1 mRNA
CTD
PMID:12517777
NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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Bax
BCL2 associated X, apoptosis regulator
affects expression
EXP
methylselenic acid affects the expression of BAX protein
CTD
PMID:12017302
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bbc3
Bcl-2 binding component 3
increases expression
ISO
methylselenic acid results in increased expression of BBC3 mRNA
CTD
PMID:28161410
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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Bcl2
BCL2, apoptosis regulator
affects expression
EXP
methylselenic acid affects the expression of BCL2 protein
CTD
PMID:12017302
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2a1
BCL2-related protein A1
increases expression
ISO
methylselenic acid results in increased expression of BCL2A1 mRNA
CTD
PMID:11830524
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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Bcl2l11
Bcl2-like 11
multiple interactions increases cleavage increases expression
ISO
BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with methylselenic acid]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; Tamoxifen promotes the reaction [methylselenic acid results in increased cleavage of BCL2L11 protein] methylselenic acid results in increased expression of BCL2L11 mRNA; methylselenic acid results in increased expression of BCL2L11 protein
CTD
PMID:17339365 PMID:18790785 PMID:28161410
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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Birc2
baculoviral IAP repeat-containing 2
affects expression
ISO
methylselenic acid affects the expression of BIRC2 mRNA
CTD
PMID:14617803
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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Birc3
baculoviral IAP repeat-containing 3
affects expression
ISO
methylselenic acid affects the expression of BIRC3 mRNA
CTD
PMID:14617803
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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Birc5
baculoviral IAP repeat-containing 5
multiple interactions decreases expression
ISO
[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of BIRC5 protein; methylselenic acid inhibits the reaction [SP1 protein binds to BIRC5 promoter] methylselenic acid results in decreased expression of BIRC5 mRNA; methylselenic acid results in decreased expression of BIRC5 protein
CTD
PMID:12517777 PMID:17876054 PMID:18444175 PMID:18567002
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bmp4
bone morphogenetic protein 4
increases expression
ISO
methylselenic acid results in increased expression of BMP4 mRNA
CTD
PMID:12517777
NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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Brca2
BRCA2, DNA repair associated
increases expression
ISO
methylselenic acid results in increased expression of BRCA2 mRNA
CTD
PMID:12517777
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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Btg3
BTG anti-proliferation factor 3
increases expression
ISO
methylselenic acid results in increased expression of BTG3 mRNA
CTD
PMID:18548127
NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
affects expression
ISO
methylselenic acid affects the expression of BUB1B mRNA
CTD
PMID:14617803
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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C1qbp
complement C1q binding protein
decreases expression
ISO
methylselenic acid results in decreased expression of C1QBP mRNA
CTD
PMID:18548127
NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
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Cadm1
cell adhesion molecule 1
affects expression
ISO
methylselenic acid affects the expression of CADM1 mRNA
CTD
PMID:14617803
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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Calm1
calmodulin 1
increases expression
ISO
methylselenic acid results in increased expression of CALM1 mRNA
CTD
PMID:18548127
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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Camk2g
calcium/calmodulin-dependent protein kinase II gamma
increases expression
ISO
methylselenic acid results in increased expression of CAMK2G mRNA
CTD
PMID:18548127
NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
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Camk4
calcium/calmodulin-dependent protein kinase IV
increases expression
ISO
methylselenic acid results in increased expression of CAMK4 mRNA
CTD
PMID:12517777
NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
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Capza1
capping actin protein of muscle Z-line subunit alpha 1
decreases expression
ISO
methylselenic acid results in decreased expression of CAPZA1 mRNA
CTD
PMID:18548127
NCBI chr 2:192,319,696...192,364,755
Ensembl chr 2:192,319,702...192,364,480
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Casp12
caspase 12
multiple interactions increases cleavage
ISO
HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein]
CTD
PMID:16204082
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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Casp3
caspase 3
multiple interactions increases cleavage
ISO
methylselenic acid results in increased cleavage of and results in increased activity of CASP3 protein methylselenic acid results in increased cleavage of CASP3 protein
CTD
PMID:19276161 PMID:28161410
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp4
caspase 4
increases cleavage
ISO
methylselenic acid results in increased cleavage of CASP4 protein
CTD
PMID:28161410
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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Casp7
caspase 7
increases cleavage multiple interactions
ISO
methylselenic acid results in increased cleavage of CASP7 protein Acetylcysteine inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; methylselenic acid inhibits the reaction [CASP7 protein binds to HSPA5 protein]; Sodium Selenite inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; Tamoxifen promotes the reaction [methylselenic acid results in increased cleavage of CASP7 protein]
CTD
PMID:16204082 PMID:18790785 PMID:28161410
NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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Casp8
caspase 8
multiple interactions increases cleavage
ISO
[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of CASP8 protein; [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; [methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP8 protein [methylselenic acid results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; methylselenic acid results in increased cleavage of CASP8 protein
CTD
PMID:18444175 PMID:18790785
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
multiple interactions increases expression increases cleavage
ISO
[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of CASP9 protein; [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; [Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein; [methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]; methylselenic acid results in increased cleavage of and results in increased activity of CASP9 protein methylselenic acid results in increased expression of CASP9 mRNA [methylselenic acid results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; methylselenic acid results in increased cleavage of CASP9 protein
CTD
PMID:12517777 PMID:17339365 PMID:18444175 PMID:18790785 PMID:28161410
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cast
calpastatin
increases expression
ISO
methylselenic acid results in increased expression of CAST mRNA
CTD
PMID:18548127
NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
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Cbx7
chromobox 7
increases expression
ISO
methylselenic acid results in increased expression of CBX7 mRNA
CTD
PMID:18548127
NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
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Cck
cholecystokinin
increases expression
ISO
methylselenic acid results in increased expression of CCK mRNA
CTD
PMID:18548127
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
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Ccna2
cyclin A2
decreases expression
ISO
methylselenic acid results in decreased expression of CCNA2 mRNA
CTD
PMID:12517777
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnb1
cyclin B1
decreases expression
ISO
methylselenic acid results in decreased expression of CCNB1 mRNA; methylselenic acid results in decreased expression of CCNB1 protein
CTD
PMID:11830524
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnd1
cyclin D1
multiple interactions affects expression decreases expression
ISO EXP
[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of CCND1 protein; KLF4 protein affects the reaction [methylselenic acid results in decreased expression of CCND1 mRNA]; methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein] methylselenic acid affects the expression of CCND1 protein methylselenic acid affects the expression of CCND1 mRNA
CTD
PMID:11830524 PMID:12017302 PMID:17847021 PMID:18314491 PMID:18444175
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccne2
cyclin E2
decreases expression
ISO
methylselenic acid results in decreased expression of CCNE2 mRNA
CTD
PMID:12517777
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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Cd14
CD14 molecule
decreases expression
ISO
methylselenic acid results in decreased expression of CD14 mRNA
CTD
PMID:18548127
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cd44
CD44 molecule (Indian blood group)
decreases expression
ISO
methylselenic acid results in decreased expression of CD44 mRNA
CTD
PMID:12517777
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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Cdc14b
cell division cycle 14B
affects expression
ISO
methylselenic acid affects the expression of CDC14B mRNA
CTD
PMID:14617803
NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235
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Cdc20
cell division cycle 20
affects expression
ISO
methylselenic acid affects the expression of CDC20 mRNA
CTD
PMID:14617803
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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Cdc25a
cell division cycle 25A
affects expression decreases expression
ISO
methylselenic acid affects the expression of CDC25A mRNA methylselenic acid results in decreased expression of CDC25A mRNA; methylselenic acid results in decreased expression of CDC25A protein
CTD
PMID:11830524 PMID:14617803
NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
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Cdc25c
cell division cycle 25C
decreases expression
ISO
methylselenic acid results in decreased expression of CDC25C mRNA
CTD
PMID:11830524
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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Cdc42
cell division cycle 42
decreases expression
ISO
methylselenic acid results in decreased expression of CDC42 mRNA
CTD
PMID:11830524
NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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Cdc42ep3
CDC42 effector protein 3
increases expression
ISO
methylselenic acid results in increased expression of CDC42EP3 mRNA
CTD
PMID:18548127
NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
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Cdc6
cell division cycle 6
decreases expression affects expression
ISO
methylselenic acid results in decreased expression of CDC6 mRNA methylselenic acid affects the expression of CDC6 mRNA
CTD
PMID:11830524 PMID:14617803
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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Cdh15
cadherin 15
increases expression
ISO
methylselenic acid results in increased expression of CDH15 mRNA
CTD
PMID:12517777
NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
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Cdh7
cadherin 7
increases expression
ISO
methylselenic acid results in increased expression of CDH7 mRNA
CTD
PMID:12517777
NCBI chr13:26,672,058...26,821,571
Ensembl chr13:26,672,484...26,819,846
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Cdk1
cyclin-dependent kinase 1
decreases expression multiple interactions
ISO
methylselenic acid results in decreased expression of CDK1 mRNA; methylselenic acid results in decreased expression of CDK1 protein HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK1 protein]
CTD
PMID:11830524 PMID:12517777 PMID:16205645
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Cdk10
cyclin-dependent kinase 10
decreases expression
ISO
methylselenic acid results in decreased expression of CDK10 mRNA
CTD
PMID:11830524
NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
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Cdk16
cyclin-dependent kinase 16
decreases expression
ISO
methylselenic acid results in decreased expression of CDK16 mRNA
CTD
PMID:12517777
NCBI chr X:1,492,814...1,504,309
Ensembl chr X:1,492,814...1,504,148
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Cdk18
cyclin-dependent kinase 18
increases expression
ISO
methylselenic acid results in increased expression of CDK18 mRNA
CTD
PMID:18548127
NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525
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Cdk2
cyclin dependent kinase 2
multiple interactions decreases expression
ISO
HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK2 protein]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein] methylselenic acid results in decreased expression of CDK2 mRNA; methylselenic acid results in decreased expression of CDK2 protein
CTD
PMID:12517777 PMID:16205645 PMID:17847021
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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Cdk4
cyclin-dependent kinase 4
multiple interactions decreases expression
ISO
methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein] methylselenic acid results in decreased expression of CDK4 mRNA
CTD
PMID:11830524 PMID:12517777 PMID:17847021 PMID:18548127
NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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Cdk5
cyclin-dependent kinase 5
increases expression
ISO
methylselenic acid results in increased expression of CDK5 mRNA
CTD
PMID:11830524
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
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Cdk6
cyclin-dependent kinase 6
multiple interactions
ISO
methylselenic acid promotes the reaction [CDKN2A protein binds to CDK6 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK6 protein]
CTD
PMID:17847021
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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Cdkl1
cyclin dependent kinase like 1
decreases expression
ISO
methylselenic acid results in decreased expression of CDKL1 mRNA
CTD
PMID:11830524
NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions affects expression increases expression
ISO EXP
DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in increased expression of and results in decreased degradation of CDKN1A protein methylselenic acid affects the expression of CDKN1A mRNA methylselenic acid results in increased expression of CDKN1A mRNA; methylselenic acid results in increased expression of CDKN1A protein methylselenic acid affects the expression of CDKN1A protein
CTD
PMID:12017302 PMID:12517777 PMID:14617803 PMID:16205645 PMID:17847021 PMID:18314491 More...
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
multiple interactions increases expression affects expression
ISO EXP
KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1B mRNA]; methylselenic acid promotes the reaction [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein]; methylselenic acid results in decreased activity of [CDKN1A protein binds to CDKN1B protein binds to CDK2 protein] methylselenic acid results in increased expression of CDKN1B mRNA; methylselenic acid results in increased expression of CDKN1B protein methylselenic acid affects the expression of CDKN1B protein
CTD
PMID:12017302 PMID:17847021 PMID:18314491
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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Cdkn1c
cyclin-dependent kinase inhibitor 1C
increases expression affects expression
ISO
methylselenic acid results in increased expression of CDKN1C mRNA methylselenic acid affects the expression of CDKN1C mRNA
CTD
PMID:14617803 PMID:18548127
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
multiple interactions increases expression
ISO
methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid promotes the reaction [CDKN2A protein binds to CDK6 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein]; methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK6 protein] methylselenic acid results in increased expression of CDKN2A protein
CTD
PMID:17847021
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Cdkn2d
cyclin dependent kinase inhibitor 2D
affects expression increases expression
ISO
methylselenic acid affects the expression of CDKN2D mRNA methylselenic acid results in increased expression of CDKN2D mRNA
CTD
PMID:12517777 PMID:14617803
NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
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Cenpa
centromere protein A
affects expression
ISO
methylselenic acid affects the expression of CENPA mRNA
CTD
PMID:14617803
NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
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Cenpf
centromere protein F
decreases expression
ISO
methylselenic acid results in decreased expression of CENPF mRNA
CTD
PMID:12517777
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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Cflar
CASP8 and FADD-like apoptosis regulator
multiple interactions
ISO
[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in decreased expression of CFLAR protein
CTD
PMID:18444175
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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Chaf1a
chromatin assembly factor 1 subunit A
decreases expression
ISO
methylselenic acid results in decreased expression of CHAF1A mRNA
CTD
PMID:12517777
NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
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Chek2
checkpoint kinase 2
increases expression
ISO
methylselenic acid results in increased expression of CHEK2 mRNA
CTD
PMID:12517777
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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Clu
clusterin
affects expression
ISO
methylselenic acid affects the expression of CLU mRNA
CTD
PMID:14617803
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Cnpy2
canopy FGF signaling regulator 2
decreases expression
ISO
methylselenic acid results in decreased expression of CNPY2 mRNA
CTD
PMID:18548127
NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519
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Col16a1
collagen type XVI alpha 1 chain
increases expression
ISO
methylselenic acid results in increased expression of COL16A1 mRNA
CTD
PMID:18548127
NCBI chr 5:142,388,376...142,442,825
Ensembl chr 5:142,388,426...142,442,825
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Col6a1
collagen type VI alpha 1 chain
increases expression
ISO
methylselenic acid results in increased expression of COL6A1 mRNA
CTD
PMID:18548127
NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
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Coro1a
coronin 1A
increases expression
ISO
methylselenic acid results in increased expression of CORO1A mRNA
CTD
PMID:12517777
NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
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Crabp2
cellular retinoic acid binding protein 2
increases expression
ISO
methylselenic acid results in increased expression of CRABP2 mRNA
CTD
PMID:18548127
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Creb1
cAMP responsive element binding protein 1
increases expression
ISO
methylselenic acid results in increased expression of CREB1 mRNA
CTD
PMID:12517777
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Creb3l1
cAMP responsive element binding protein 3-like 1
decreases expression
ISO
methylselenic acid results in decreased expression of CREB3L1 mRNA
CTD
PMID:18548127
NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
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Creb3l4
cAMP responsive element binding protein 3-like 4
affects expression
ISO
methylselenic acid affects the expression of CREB3L4 mRNA
CTD
PMID:14617803
NCBI chr 2:175,690,340...175,696,084
Ensembl chr 2:175,690,335...175,695,932
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Cryab
crystallin, alpha B
increases expression
ISO
methylselenic acid results in increased expression of CRYAB mRNA
CTD
PMID:18548127
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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Csrp1
cysteine and glycine-rich protein 1
increases expression
ISO
methylselenic acid results in increased expression of CSRP1 mRNA
CTD
PMID:18548127
NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
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Ctsk
cathepsin K
increases expression
ISO
methylselenic acid results in increased expression of CTSK mRNA
CTD
PMID:18548127
NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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Cul1
cullin 1
increases expression
ISO
methylselenic acid results in increased expression of CUL1 mRNA
CTD
PMID:18548127
NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
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Cyld
CYLD lysine 63 deubiquitinase
increases expression
ISO
methylselenic acid results in increased expression of CYLD mRNA
CTD
PMID:18548127
NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
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Ddit3
DNA-damage inducible transcript 3
multiple interactions increases expression
ISO
DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of DDIT3 protein] methylselenic acid results in increased expression of DDIT3 mRNA; methylselenic acid results in increased expression of DDIT3 protein
CTD
PMID:11830524 PMID:12517777 PMID:16204082 PMID:16205645 PMID:19276161 PMID:28161410 More...
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Deaf1
DEAF1 transcription factor
decreases expression
ISO
methylselenic acid results in decreased expression of DEAF1 mRNA
CTD
PMID:18548127
NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
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Dhcr24
24-dehydrocholesterol reductase
multiple interactions decreases expression
ISO
AR protein inhibits the reaction [methylselenic acid results in decreased expression of DHCR24 mRNA]
CTD
PMID:16020662 PMID:18548127
NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
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Dhfr
dihydrofolate reductase
decreases expression
ISO
methylselenic acid results in decreased expression of DHFR mRNA
CTD
PMID:12517777
NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
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Dixdc1
DIX domain containing 1
increases expression
ISO
methylselenic acid results in increased expression of DIXDC1 mRNA
CTD
PMID:18548127
NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090
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Dkc1
dyskerin pseudouridine synthase 1
decreases expression
ISO
methylselenic acid results in decreased expression of DKC1 mRNA
CTD
PMID:18548127
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Dlc1
DLC1 Rho GTPase activating protein
increases expression
ISO
methylselenic acid results in increased expression of DLC1 mRNA
CTD
PMID:12517777
NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
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Dnajb5
DnaJ heat shock protein family (Hsp40) member B5
increases expression
ISO
methylselenic acid results in increased expression of DNAJB5 mRNA
CTD
PMID:18548127
NCBI chr 5:57,176,840...57,185,492
Ensembl chr 5:57,176,845...57,185,490
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Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
affects expression
ISO
methylselenic acid affects the expression of DNAJB9 mRNA
CTD
PMID:14617803
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
decreases expression
ISO
methylselenic acid results in decreased expression of DNPH1 mRNA
CTD
PMID:18548127
NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
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Dpyd
dihydropyrimidine dehydrogenase
increases expression
ISO
methylselenic acid results in increased expression of DPYD mRNA
CTD
PMID:18548127
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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Dpysl2
dihydropyrimidinase-like 2
increases expression
ISO
methylselenic acid results in increased expression of DPYSL2 mRNA
CTD
PMID:18548127
NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
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Dtna
dystrobrevin, alpha
increases expression
ISO
methylselenic acid results in increased expression of DTNA mRNA
CTD
PMID:18548127
NCBI chr18:14,687,193...14,944,232
Ensembl chr18:14,587,852...14,944,261
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Dtymk
deoxythymidylate kinase
decreases expression
ISO
methylselenic acid results in decreased expression of DTYMK mRNA
CTD
PMID:12517777
NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
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Dusp10
dual specificity phosphatase 10
increases expression
ISO
methylselenic acid results in increased expression of DUSP10 mRNA
CTD
PMID:12517777
NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
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Dvl3
dishevelled segment polarity protein 3
increases expression
ISO
methylselenic acid results in increased expression of DVL3 mRNA
CTD
PMID:18548127
NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462
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Dync1i1
dynein cytoplasmic 1 intermediate chain 1
increases expression
ISO
methylselenic acid results in increased expression of DYNC1I1 mRNA
CTD
PMID:18548127
NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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E2f1
E2F transcription factor 1
decreases expression multiple interactions affects expression
ISO
methylselenic acid results in decreased expression of E2F1 mRNA; methylselenic acid results in decreased expression of E2F1 protein methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein] methylselenic acid affects the expression of E2F1 mRNA
CTD
PMID:11830524 PMID:14617803 PMID:17847021
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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E2f5
E2F transcription factor 5
decreases expression
ISO
methylselenic acid results in decreased expression of E2F5 mRNA
CTD
PMID:11830524
NCBI chr 2:86,997,331...87,012,901
Ensembl chr 2:86,997,332...87,012,990
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Eci1
enoyl-CoA delta isomerase 1
decreases expression
ISO
methylselenic acid results in decreased expression of ECI1 mRNA
CTD
PMID:18548127
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
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Ecm2
extracellular matrix protein 2
increases expression
ISO
methylselenic acid results in increased expression of ECM2 mRNA
CTD
PMID:18548127
NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516
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Ednra
endothelin receptor type A
increases expression
ISO
methylselenic acid results in increased expression of EDNRA mRNA
CTD
PMID:18548127
NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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Ednrb
endothelin receptor type B
increases expression
ISO
methylselenic acid results in increased expression of EDNRB mRNA
CTD
PMID:18548127
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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Efemp2
EGF containing fibulin extracellular matrix protein 2
increases expression
ISO
methylselenic acid results in increased expression of EFEMP2 mRNA
CTD
PMID:18548127
NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414
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Egr1
early growth response 1
increases expression
ISO
methylselenic acid results in increased expression of EGR1 mRNA
CTD
PMID:11172735
NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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Eif2a
eukaryotic translation initiation factor 2A
increases phosphorylation multiple interactions
ISO
methylselenic acid results in increased phosphorylation of EIF2A protein HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2A protein]
CTD
PMID:16204082
NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
multiple interactions
ISO
HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2AK3 protein]; methylselenic acid results in increased phosphorylation of and results in increased activity of EIF2AK3 protein
CTD
PMID:16204082 PMID:16205645
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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Eif4g2
eukaryotic translation initiation factor 4, gamma 2
decreases expression
ISO
methylselenic acid results in decreased expression of EIF4G2 mRNA
CTD
PMID:12517777
NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
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Elf3
E74 like ETS transcription factor 3
increases expression affects expression
ISO
methylselenic acid results in increased expression of ELF3 mRNA methylselenic acid affects the expression of ELF3 mRNA
CTD
PMID:12517777 PMID:14617803
NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
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Eno2
enolase 2
increases expression
ISO
methylselenic acid results in increased expression of ENO2 mRNA
CTD
PMID:18548127
NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
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Epb41l2
erythrocyte membrane protein band 4.1-like 2
increases expression
ISO
methylselenic acid results in increased expression of EPB41L2 mRNA
CTD
PMID:18548127
NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721
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Eps8
epidermal growth factor receptor pathway substrate 8
increases expression
ISO
methylselenic acid results in increased expression of EPS8 mRNA
CTD
PMID:18548127
NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
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Ercc1
ERCC excision repair 1, endonuclease non-catalytic subunit
increases expression
ISO
methylselenic acid results in increased expression of ERCC1 mRNA
CTD
PMID:12517777
NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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Esr1
estrogen receptor 1
multiple interactions decreases expression
ISO
[methylselenic acid co-treated with afimoxifene] results in decreased expression of ESR1 mRNA; [methylselenic acid co-treated with afimoxifene] results in decreased expression of ESR1 protein; methylselenic acid inhibits the reaction [Estradiol binds to ESR1 protein]; methylselenic acid results in decreased expression of and results in decreased activity of ESR1 protein methylselenic acid results in decreased expression of ESR1 mRNA; methylselenic acid results in decreased expression of ESR1 protein
CTD
PMID:15833885 PMID:16093440 PMID:16155795
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esr2
estrogen receptor 2
affects expression increases expression
ISO
methylselenic acid affects the expression of ESR2 mRNA methylselenic acid results in increased expression of ESR2 mRNA
CTD
PMID:15833885 PMID:16928829
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Etv5
ETS variant transcription factor 5
increases expression
ISO
methylselenic acid results in increased expression of ETV5 mRNA
CTD
PMID:18548127
NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215
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Etv6
ETS variant transcription factor 6
increases expression
ISO
methylselenic acid results in increased expression of ETV6 mRNA
CTD
PMID:18548127
NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
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Ext1
exostosin glycosyltransferase 1
increases expression
ISO
methylselenic acid results in increased expression of EXT1 mRNA
CTD
PMID:18548127
NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
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Fam107a
family with sequence similarity 107, member A
increases expression
ISO
methylselenic acid results in increased expression of FAM107A mRNA
CTD
PMID:18548127
NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
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Fbxl8
F-box and leucine-rich repeat protein 8
increases expression
ISO
methylselenic acid results in increased expression of FBXL8 mRNA
CTD
PMID:18548127
NCBI chr19:33,142,653...33,147,268
Ensembl chr19:33,142,715...33,147,262
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Fermt2
FERM domain containing kindlin 2
increases expression
ISO
methylselenic acid results in increased expression of FERMT2 mRNA
CTD
PMID:18548127
NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
G
Fez1
fasciculation and elongation protein zeta 1
increases expression
ISO
methylselenic acid results in increased expression of FEZ1 mRNA
CTD
PMID:18548127
NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
G
Fgf2
fibroblast growth factor 2
decreases expression
ISO
methylselenic acid results in decreased expression of FGF2 mRNA
CTD
PMID:12517777
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
G
Fhl2
four and a half LIM domains 2
increases expression
ISO
methylselenic acid results in increased expression of FHL2 mRNA
CTD
PMID:18548127
NCBI chr 9:45,388,979...45,462,530
Ensembl chr 9:45,388,981...45,431,192
G
Fkbp4
FKBP prolyl isomerase 4
decreases expression
ISO
methylselenic acid results in decreased expression of FKBP4 mRNA
CTD
PMID:18548127
NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
G
Fkbp5
FKBP prolyl isomerase 5
affects expression
ISO
methylselenic acid affects the expression of FKBP5 mRNA
CTD
PMID:14617803
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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Flnc
filamin C
increases expression
ISO
methylselenic acid results in increased expression of FLNC mRNA
CTD
PMID:18548127
NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
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Fn1
fibronectin 1
affects expression
ISO
methylselenic acid affects the expression of FN1 mRNA
CTD
PMID:14617803
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
G
Fnbp1
formin binding protein 1
increases expression
ISO
methylselenic acid results in increased expression of FNBP1 mRNA
CTD
PMID:18548127
NCBI chr 3:14,316,011...14,386,704
Ensembl chr 3:14,309,640...14,424,881
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Foxa1
forkhead box A1
decreases expression
ISO
methylselenic acid results in decreased expression of FOXA1 mRNA
CTD
PMID:12517777 PMID:18548127
NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
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Foxo3
forkhead box O3
multiple interactions
ISO
methylselenic acid results in decreased phosphorylation of and results in increased activity of FOXO3 protein
CTD
PMID:17339365
NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
G
Fyn
FYN proto-oncogene, Src family tyrosine kinase
increases expression
ISO
methylselenic acid results in increased expression of FYN mRNA
CTD
PMID:18548127
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
G
Gabarapl1
GABA type A receptor associated protein like 1
increases expression
ISO
methylselenic acid results in increased expression of GABARAPL1 mRNA
CTD
PMID:18548127
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
methylselenic acid results in increased expression of GADD45A mRNA
CTD
PMID:12517777
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Galnt1
polypeptide N-acetylgalactosaminyltransferase 1
decreases expression
ISO
methylselenic acid results in decreased expression of GALNT1 mRNA
CTD
PMID:18548127
NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
G
Gas1
growth arrest-specific 1
increases expression
ISO
methylselenic acid results in increased expression of GAS1 mRNA
CTD
PMID:18548127
NCBI chr17:4,482,014...4,485,155
G
Gatd3a
glutamine amidotransferase class 1 domain containing 3A
decreases expression
ISO
methylselenic acid results in decreased expression of GATD3 mRNA
CTD
PMID:18548127
NCBI chr20:10,514,793...10,522,894
Ensembl chr20:10,514,744...10,522,885
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Gbp2
guanylate binding protein 2
increases expression
ISO
methylselenic acid results in increased expression of GBP2 mRNA
CTD
PMID:18548127
NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
G
Gja1
gap junction protein, alpha 1
increases expression
ISO
methylselenic acid results in increased expression of GJA1 mRNA
CTD
PMID:18548127
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gpr161
G protein-coupled receptor 161
increases expression
ISO
methylselenic acid results in increased expression of GPR161 mRNA
CTD
PMID:18548127
NCBI chr13:77,578,257...77,623,661
Ensembl chr13:77,577,739...77,619,613
G
Gpr37
G protein-coupled receptor 37
increases expression
ISO
methylselenic acid results in increased expression of GPR37 mRNA
CTD
PMID:12517777
NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001
G
Grk5
G protein-coupled receptor kinase 5
increases expression
ISO
methylselenic acid results in increased expression of GRK5 mRNA
CTD
PMID:18548127
NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
G
Gsk3b
glycogen synthase kinase 3 beta
multiple interactions decreases phosphorylation
ISO
methylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein] methylselenic acid results in decreased phosphorylation of GSK3B protein
CTD
PMID:17339365
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Gsn
gelsolin
increases expression
ISO
methylselenic acid results in increased expression of GSN mRNA
CTD
PMID:18548127
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
G
Gtf3c1
general transcription factor IIIC subunit 1
decreases expression
ISO
methylselenic acid results in decreased expression of GTF3C1 mRNA
CTD
PMID:18548127
NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
G
Gucy1a1
guanylate cyclase 1 soluble subunit alpha 1
affects expression multiple interactions decreases expression
ISO
methylselenic acid affects the expression of GUCY1A1 mRNA AR protein inhibits the reaction [methylselenic acid results in decreased expression of GUCY1A1 mRNA]
CTD
PMID:14617803 PMID:16020662 PMID:18548127
NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
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H1f0
H1.0 linker histone
affects expression
ISO
methylselenic acid affects the expression of H1-0 mRNA
CTD
PMID:14617803
NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
G
H2ac18
H2A clustered histone 18
decreases expression
ISO
methylselenic acid results in decreased expression of H2AC18 mRNA
CTD
PMID:18548127
NCBI chr 2:183,808,398...183,808,922
G
Habp4
hyaluronan binding protein 4
increases expression
ISO
methylselenic acid results in increased expression of HABP4 mRNA
CTD
PMID:18548127
NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565
G
Hacd2
3-hydroxyacyl-CoA dehydratase 2
decreases expression
ISO
methylselenic acid results in decreased expression of HACD2 mRNA
CTD
PMID:18548127
NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889
G
Heph
hephaestin
increases expression
ISO
methylselenic acid results in increased expression of HEPH mRNA
CTD
PMID:18548127
NCBI chr X:61,151,131...61,402,980
Ensembl chr X:61,296,345...61,402,980
G
Hist1h2af
histone cluster 1 H2A family member F
decreases expression
ISO
methylselenic acid results in decreased expression of H2AC8 mRNA
CTD
PMID:18548127
NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
G
Hmgn2-ps3
high mobility group nucleosomal binding domain 2, pseudogene 3
increases expression
ISO
methylselenic acid results in increased expression of HMGN4 mRNA
CTD
PMID:18548127
NCBI chr 3:99,990,743...99,991,093
Ensembl chr 3:99,990,743...99,991,003
G
Hnrnpab
heterogeneous nuclear ribonucleoprotein A/B
decreases expression
ISO
methylselenic acid results in decreased expression of HNRNPAB mRNA
CTD
PMID:18548127
NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
G
Hoxa9
homeobox A9
decreases expression
ISO
methylselenic acid results in decreased expression of HOXA9 mRNA
CTD
PMID:18548127
NCBI chr 4:81,323,235...81,329,344
Ensembl chr 4:81,323,382...81,326,358
G
Hoxd8
homeobox D8
increases expression
ISO
methylselenic acid results in increased expression of HOXD8 mRNA
CTD
PMID:12517777
NCBI chr 3:59,607,864...59,610,358
Ensembl chr 3:59,607,996...59,610,361
G
Hpgd
15-hydroxyprostaglandin dehydrogenase
increases expression
ISO
methylselenic acid results in increased expression of HPGD mRNA; methylselenic acid results in increased expression of HPGD protein
CTD
PMID:25187657
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
G
Hpgds
hematopoietic prostaglandin D synthase
increases expression
ISO
methylselenic acid results in increased expression of HPGDS mRNA
CTD
PMID:21669866
NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
G
Hsp90b1
heat shock protein 90 beta family member 1
increases expression multiple interactions
ISO
methylselenic acid results in increased expression of HSP90B1 protein HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSP90B1 protein]
CTD
PMID:16204082
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
G
Hspa4l
heat shock protein family A (Hsp70) member 4 like
increases expression
ISO
methylselenic acid results in increased expression of HSPA4L mRNA
CTD
PMID:18548127
NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions increases expression
ISO
HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK1 protein]; HSPA5 protein affects the reaction [methylselenic acid results in decreased expression of CDK2 protein]; HSPA5 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of PARP1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of DDIT3 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSP90B1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased expression of HSPA5 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2A protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2AK3 protein]; methylselenic acid inhibits the reaction [CASP7 protein binds to HSPA5 protein] methylselenic acid results in increased expression of HSPA5 mRNA; methylselenic acid results in increased expression of HSPA5 protein
CTD
PMID:16204082 PMID:16205645 PMID:28161410
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Id1
inhibitor of DNA binding 1
decreases expression
ISO
methylselenic acid results in decreased expression of ID1 mRNA
CTD
PMID:12517777
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
G
Id2
inhibitor of DNA binding 2
affects expression
ISO
methylselenic acid affects the expression of ID2 mRNA
CTD
PMID:14617803
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
G
Id3
inhibitor of DNA binding 3
decreases expression increases expression
ISO
methylselenic acid results in decreased expression of ID3 mRNA methylselenic acid results in increased expression of ID3 mRNA
CTD
PMID:12517777 PMID:18548127
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
G
Ids
iduronate 2-sulfatase
increases expression
ISO
methylselenic acid results in increased expression of IDS mRNA
CTD
PMID:18548127
NCBI chr X:149,025,977...149,046,639
Ensembl chr X:149,025,976...149,046,663
G
Ifrd2
interferon-related developmental regulator 2
decreases expression
ISO
methylselenic acid results in decreased expression of IFRD2 mRNA
CTD
PMID:18548127
NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194
G
Igf1
insulin-like growth factor 1
increases expression
ISO
methylselenic acid results in increased expression of IGF1 mRNA
CTD
PMID:11830524
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igsf3
immunoglobulin superfamily, member 3
affects expression
ISO
methylselenic acid affects the expression of IGSF3 mRNA
CTD
PMID:14617803
NCBI chr 2:188,811,394...188,899,645
Ensembl chr 2:188,811,380...188,899,645
G
Ing1
inhibitor of growth family, member 1
affects expression
ISO
methylselenic acid affects the expression of ING1 mRNA
CTD
PMID:14617803
NCBI chr16:77,937,276...77,945,320
Ensembl chr16:77,937,279...77,946,264
G
Inpp4b
inositol polyphosphate-4-phosphatase type II B
affects expression
ISO
methylselenic acid affects the expression of INPP4B mRNA
CTD
PMID:14617803
NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
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Ipo8
importin 8
increases expression
ISO
methylselenic acid results in increased expression of IPO8 mRNA
CTD
PMID:12517777
NCBI chr 4:181,729,216...181,793,673
Ensembl chr 4:181,729,220...181,793,161
G
Irf1
interferon regulatory factor 1
affects expression
ISO
methylselenic acid affects the expression of IRF1 mRNA
CTD
PMID:14617803
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
G
Itga3
integrin subunit alpha 3
increases expression
ISO
methylselenic acid results in increased expression of ITGA3 mRNA
CTD
PMID:18548127
NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
G
Itgb1
integrin subunit beta 1
decreases expression
ISO
methylselenic acid results in decreased expression of ITGB1 mRNA
CTD
PMID:11172735
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
G
Itgb3bp
integrin subunit beta 3 binding protein
decreases expression
ISO
methylselenic acid results in decreased expression of ITGB3BP mRNA
CTD
PMID:12517777
NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704
G
Itgb4
integrin subunit beta 4
decreases expression
ISO
methylselenic acid results in decreased expression of ITGB4 mRNA
CTD
PMID:12517777
NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
G
Itgb5
integrin subunit beta 5
decreases expression
ISO
methylselenic acid results in decreased expression of ITGB5 mRNA
CTD
PMID:12517777
NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
G
Itpr1
inositol 1,4,5-trisphosphate receptor, type 1
increases expression
ISO
methylselenic acid results in increased expression of ITPR1 mRNA
CTD
PMID:18548127
NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
G
Jak1
Janus kinase 1
affects expression increases expression
ISO
methylselenic acid affects the expression of JAK1 mRNA methylselenic acid results in increased expression of JAK1 mRNA
CTD
PMID:14617803 PMID:18548127
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
decreases expression affects expression
ISO
methylselenic acid results in decreased expression of JUN protein methylselenic acid affects the expression of JUN mRNA
CTD
PMID:11830524
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Junb
JunB proto-oncogene, AP-1 transcription factor subunit
decreases expression
ISO
methylselenic acid results in decreased expression of JUNB mRNA
CTD
PMID:12517777
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
G
Kcnab1
potassium voltage-gated channel subfamily A regulatory beta subunit 1
increases expression
ISO
methylselenic acid results in increased expression of KCNAB1 mRNA
CTD
PMID:18548127
NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
G
Kcnh2
potassium voltage-gated channel subfamily H member 2
increases expression
ISO
methylselenic acid results in increased expression of KCNH2 mRNA
CTD
PMID:18548127
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
G
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
increases expression
ISO
methylselenic acid results in increased expression of KCNJ8 mRNA
CTD
PMID:18548127
NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
G
Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
decreases expression
ISO
methylselenic acid results in decreased expression of KDELR2 mRNA
CTD
PMID:18548127
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
G
Kif11
kinesin family member 11
decreases expression
ISO
methylselenic acid results in decreased expression of KIF11 mRNA
CTD
PMID:12517777
NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
G
Kif20b
kinesin family member 20B
decreases expression
ISO
methylselenic acid results in decreased expression of KIF20B mRNA
CTD
PMID:12517777
NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
G
Klf4
KLF transcription factor 4
multiple interactions affects expression increases activity increases expression
ISO
KLF4 protein affects the reaction [methylselenic acid results in decreased expression of CCND1 mRNA]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA]; KLF4 protein affects the reaction [methylselenic acid results in increased expression of CDKN1B mRNA] methylselenic acid affects the expression of KLF4 mRNA methylselenic acid results in increased activity of KLF4 protein methylselenic acid results in increased expression of KLF4 mRNA
CTD
PMID:14617803 PMID:18314491
NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
G
Klhl2
kelch-like family member 2
affects expression
ISO
methylselenic acid affects the expression of KLHL2 mRNA
CTD
PMID:14617803
NCBI chr16:24,860,763...24,973,348
Ensembl chr16:24,860,667...24,973,341
G
Krt15
keratin 15
increases expression
ISO
methylselenic acid results in increased expression of KRT15 mRNA
CTD
PMID:18548127
NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799
G
Krt20
keratin 20
increases expression
ISO
methylselenic acid results in increased expression of KRT20 mRNA
CTD
PMID:12517777
NCBI chr10:84,384,802...84,394,107
Ensembl chr10:84,384,802...84,394,107
G
Lage3
L antigen family, member 3
decreases expression
ISO
methylselenic acid results in decreased expression of LAGE3 mRNA
CTD
PMID:18548127
NCBI chr X:152,138,209...152,139,632
Ensembl chr X:152,138,218...152,139,632
G
Lama4
laminin subunit alpha 4
increases expression
ISO
methylselenic acid results in increased expression of LAMA4 mRNA
CTD
PMID:18548127
NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
G
Lamb3
laminin subunit beta 3
increases expression
ISO
methylselenic acid results in increased expression of LAMB3 mRNA
CTD
PMID:18548127
NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
G
Lmnb2
lamin B2
decreases expression
ISO
methylselenic acid results in decreased expression of LMNB2 mRNA
CTD
PMID:12517777
NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
G
LOC684932
similar to Zinc finger protein 75
increases expression
ISO
methylselenic acid results in increased expression of ZNF75D mRNA
CTD
PMID:12517777
NCBI chr X:134,035,116...134,053,765
Ensembl chr X:134,036,143...134,051,519
G
Lypla1
lysophospholipase 1
decreases expression
ISO
methylselenic acid results in decreased expression of LYPLA1 mRNA
CTD
PMID:18548127
NCBI chr 5:14,679,605...14,708,774
Ensembl chr 5:14,679,606...14,708,746
G
Maea
macrophage erythroblast attacher, E3 ubiquitin ligase
decreases expression
ISO
methylselenic acid results in decreased expression of MAEA mRNA
CTD
PMID:18548127
NCBI chr14:77,357,261...77,390,683
Ensembl chr14:77,357,264...77,390,671
G
Maf
MAF bZIP transcription factor
increases expression
ISO
methylselenic acid results in increased expression of MAF mRNA
CTD
PMID:18548127
NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
G
Map1b
microtubule-associated protein 1B
affects expression increases expression
ISO
methylselenic acid affects the expression of MAP1B mRNA methylselenic acid results in increased expression of MAP1B mRNA
CTD
PMID:14617803 PMID:18548127
NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
G
Map2k1
mitogen activated protein kinase kinase 1
decreases expression increases expression
ISO
methylselenic acid results in decreased expression of MAP2K1 mRNA methylselenic acid results in increased expression of MAP2K1 mRNA
CTD
PMID:11830524 PMID:12517777
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Map2k5
mitogen activated protein kinase kinase 5
increases expression
ISO
methylselenic acid results in increased expression of MAP2K5 mRNA
CTD
PMID:12517777
NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
G
Mapk1
mitogen activated protein kinase 1
increases phosphorylation
ISO
methylselenic acid results in increased phosphorylation of MAPK1 protein
CTD
PMID:15845651
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
increases expression increases phosphorylation
ISO
methylselenic acid results in increased expression of MAPK3 mRNA methylselenic acid results in increased phosphorylation of MAPK3 protein
CTD
PMID:11830524 PMID:15845651
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
increases expression
ISO
methylselenic acid results in increased expression of MAPK8 mRNA
CTD
PMID:12517777
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mapk9
mitogen-activated protein kinase 9
decreases expression
ISO
methylselenic acid results in decreased expression of MAPK9 mRNA
CTD
PMID:11830524
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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Mapre2
microtubule-associated protein, RP/EB family, member 2
increases expression
ISO
methylselenic acid results in increased expression of MAPRE2 mRNA
CTD
PMID:18548127
NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044
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Mapt
microtubule-associated protein tau
decreases expression
ISO
methylselenic acid results in decreased expression of MAPT mRNA
CTD
PMID:12517777
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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Maz
MYC associated zinc finger protein
decreases expression
ISO
methylselenic acid results in decreased expression of MAZ mRNA
CTD
PMID:12517777
NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408
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Mbnl2
muscleblind-like splicing regulator 2
increases expression
ISO
methylselenic acid results in increased expression of MBNL2 mRNA
CTD
PMID:18548127
NCBI chr15:97,385,238...97,542,924
Ensembl chr15:97,385,244...97,542,937
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Mccc2
methylcrotonyl-CoA carboxylase subunit 2
decreases expression
ISO
methylselenic acid results in decreased expression of MCCC2 mRNA
CTD
PMID:18548127
NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
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Mcm2
minichromosome maintenance complex component 2
affects expression
ISO
methylselenic acid affects the expression of MCM2 mRNA
CTD
PMID:14617803
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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Mcm3
minichromosome maintenance complex component 3
decreases expression
ISO
methylselenic acid results in decreased expression of MCM3 mRNA
CTD
PMID:12517777
NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
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Mcm5
minichromosome maintenance complex component 5
decreases expression
ISO
methylselenic acid results in decreased expression of MCM5 mRNA
CTD
PMID:12517777
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
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Mcm6
minichromosome maintenance complex component 6
decreases expression affects expression
ISO
methylselenic acid results in decreased expression of MCM6 mRNA methylselenic acid affects the expression of MCM6 mRNA
CTD
PMID:12517777 PMID:14617803
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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Mcm7
minichromosome maintenance complex component 7
decreases expression
ISO
methylselenic acid results in decreased expression of MCM7 mRNA
CTD
PMID:12517777
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
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Me1
malic enzyme 1
increases expression
ISO
methylselenic acid results in increased expression of ME1 mRNA
CTD
PMID:18548127
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Mef2c
myocyte enhancer factor 2C
increases expression
ISO
methylselenic acid results in increased expression of MEF2C mRNA
CTD
PMID:18548127
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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Men1
menin 1
affects expression
ISO
methylselenic acid affects the expression of MEN1 mRNA
CTD
PMID:14617803
NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
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Micu2
mitochondrial calcium uptake 2
decreases expression
ISO
methylselenic acid results in decreased expression of MICU2 mRNA
CTD
PMID:18548127
NCBI chr15:32,064,872...32,146,874
Ensembl chr15:32,064,875...32,147,094
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Mitf
melanocyte inducing transcription factor
increases expression
ISO
methylselenic acid results in increased expression of MITF mRNA
CTD
PMID:18548127
NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
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Mki67
marker of proliferation Ki-67
decreases expression
ISO
methylselenic acid results in decreased expression of MKI67 mRNA
CTD
PMID:12517777
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mrpl19
mitochondrial ribosomal protein L19
decreases expression
ISO
methylselenic acid results in decreased expression of MRPL19 mRNA
CTD
PMID:18548127
NCBI chr 4:114,521,824...114,526,053
Ensembl chr 4:114,521,824...114,526,053
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Mxd1
max dimerization protein 1
affects expression
ISO
methylselenic acid affects the expression of MXD1 mRNA
CTD
PMID:14617803
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
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Mxi1
MAX interactor 1, dimerization protein
increases expression
ISO
methylselenic acid results in increased expression of MXI1 mRNA
CTD
PMID:18548127
NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
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Mybl2
MYB proto-oncogene like 2
decreases expression
ISO
methylselenic acid results in decreased expression of MYBL2 mRNA
CTD
PMID:12517777
NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
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Myc
MYC proto-oncogene, bHLH transcription factor
multiple interactions affects expression
ISO
methylselenic acid inhibits the reaction [afimoxifene results in increased expression of MYC mRNA]; methylselenic acid inhibits the reaction [Estradiol results in increased expression of MYC mRNA] methylselenic acid affects the expression of MYC mRNA
CTD
PMID:14617803 PMID:15833885 PMID:16093440 PMID:16155795
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myl9
myosin light chain 9
increases expression
ISO
methylselenic acid results in increased expression of MYL9 mRNA
CTD
PMID:18548127
NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
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Myo10
myosin X
decreases expression
ISO
methylselenic acid results in decreased expression of MYO10 mRNA
CTD
PMID:18548127
NCBI chr 2:76,100,962...76,304,164
Ensembl chr 2:76,100,987...76,303,030
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Myrip
myosin VIIA and Rab interacting protein
decreases expression
ISO
methylselenic acid results in decreased expression of MYRIP mRNA
CTD
PMID:18548127
NCBI chr 8:120,017,843...120,184,821
Ensembl chr 8:120,017,524...120,183,833
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Naaa
N-acylethanolamine acid amidase
decreases expression
ISO
methylselenic acid results in decreased expression of NAAA mRNA
CTD
PMID:18548127
NCBI chr14:15,777,306...15,796,411
Ensembl chr14:15,777,306...15,796,410
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Ncoa1
nuclear receptor coactivator 1
multiple interactions
ISO
methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [NCOA1 protein binds to KLK3 promoter]]
CTD
PMID:16648561
NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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Ncoa2
nuclear receptor coactivator 2
multiple interactions
ISO
methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [NCOA2 protein binds to KLK3 promoter]]
CTD
PMID:16648561
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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Ncor1
nuclear receptor co-repressor 1
multiple interactions
ISO
methylselenic acid inhibits the reaction [Dihydrotestosterone inhibits the reaction [NCOR1 protein binds to KLK3 promoter]]
CTD
PMID:16648561
NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
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Ncor2
nuclear receptor co-repressor 2
multiple interactions
ISO
methylselenic acid inhibits the reaction [Dihydrotestosterone inhibits the reaction [NCOR2 protein binds to KLK3 promoter]]
CTD
PMID:16648561
NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
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Ndrg1
N-myc downstream regulated 1
affects expression
ISO
methylselenic acid affects the expression of NDRG1 mRNA
CTD
PMID:14617803
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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Nebl
nebulette
increases expression
ISO
methylselenic acid results in increased expression of NEBL mRNA
CTD
PMID:18548127
NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210
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Nfil3
nuclear factor, interleukin 3 regulated
affects expression
ISO
methylselenic acid affects the expression of NFIL3 mRNA
CTD
PMID:14617803
NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
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Nfkb1
nuclear factor kappa B subunit 1
decreases expression
ISO
methylselenic acid results in decreased expression of NFKB1 mRNA
CTD
PMID:12517777
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nkx3-1
NK3 homeobox 1
affects expression
ISO
methylselenic acid affects the expression of NKX3-1 mRNA
CTD
PMID:14617803
NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
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Nme1
NME/NM23 nucleoside diphosphate kinase 1
decreases expression
ISO
methylselenic acid results in decreased expression of NME1 mRNA
CTD
PMID:18548127
NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
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Nme4
NME/NM23 nucleoside diphosphate kinase 4
decreases expression
ISO
methylselenic acid results in decreased expression of NME4 mRNA
CTD
PMID:18548127
NCBI chr10:15,114,624...15,118,479
Ensembl chr10:15,002,926...15,118,479
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Nmi
N-myc (and STAT) interactor
decreases expression
ISO
methylselenic acid results in decreased expression of NMI mRNA
CTD
PMID:12517777
NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases activity
ISO
methylselenic acid results in increased activity of NQO1 protein
CTD
PMID:14617803
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
ISO
methylselenic acid affects the expression of NR3C1 mRNA
CTD
PMID:16928829
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Oat
ornithine aminotransferase
increases expression
ISO
methylselenic acid results in increased expression of OAT mRNA
CTD
PMID:18548127
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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Olfml2a
olfactomedin-like 2A
increases expression
ISO
methylselenic acid results in increased expression of OLFML2A mRNA
CTD
PMID:18548127
NCBI chr 3:22,688,562...22,717,745
Ensembl chr 3:22,688,598...22,717,909
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Optn
optineurin
increases expression
ISO
methylselenic acid results in increased expression of OPTN mRNA
CTD
PMID:18548127
NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions increases cleavage
ISO
[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of PARP1 protein; [Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]; HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of PARP1 protein]; SB 216763 inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]
CTD
PMID:15845651 PMID:16204082 PMID:17339365 PMID:18444175 PMID:19276161 PMID:28161410 More...
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Patz1
POZ (BTB) and AT hook containing zinc finger 1
decreases expression
ISO
methylselenic acid results in decreased expression of PATZ1 mRNA
CTD
PMID:12517777
NCBI chr14:78,154,590...78,173,032
Ensembl chr14:78,152,516...78,173,032
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Paxip1
PAX interacting protein 1
decreases expression
ISO
methylselenic acid results in decreased expression of PAXIP1 mRNA
CTD
PMID:18548127
NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548
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Pbx1
PBX homeobox 1
increases expression
ISO
methylselenic acid results in increased expression of PBX1 mRNA
CTD
PMID:18548127
NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
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Pcbd1
pterin-4 alpha-carbinolamine dehydratase 1
decreases expression
ISO
methylselenic acid results in decreased expression of PCBD1 mRNA
CTD
PMID:18548127
NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292 Ensembl chr20:28,953,864...29,044,292
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Pcna
proliferating cell nuclear antigen
affects expression decreases expression
ISO
methylselenic acid affects the expression of PCNA mRNA methylselenic acid results in decreased expression of PCNA mRNA
CTD
PMID:11830524 PMID:12517777 PMID:14617803
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Peg3
paternally expressed 3
affects expression
ISO
methylselenic acid affects the expression of PEG3 mRNA
CTD
PMID:14617803
NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:67,097,904...67,124,671
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Pfdn5
prefoldin subunit 5
decreases expression
ISO
methylselenic acid results in decreased expression of PFDN5 mRNA
CTD
PMID:11830524
NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516
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Pgap2
post-GPI attachment to proteins 2
decreases expression
ISO
methylselenic acid results in decreased expression of PGAP2 mRNA
CTD
PMID:18548127
NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114
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Pgm5
phosphoglucomutase 5
increases expression
ISO
methylselenic acid results in increased expression of PGM5 mRNA
CTD
PMID:18548127
NCBI chr 1:222,325,638...222,513,423
Ensembl chr 1:222,325,643...222,513,437
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Pgr
progesterone receptor
affects expression
ISO
methylselenic acid affects the expression of PGR mRNA
CTD
PMID:16928829
NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Pja2
praja ring finger ubiquitin ligase 2
increases expression
ISO
methylselenic acid results in increased expression of PJA2 mRNA
CTD
PMID:18548127
NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783
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Pla2g4a
phospholipase A2 group IVA
increases expression
ISO
methylselenic acid results in increased expression of PLA2G4A mRNA
CTD
PMID:18548127
NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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Plcb4
phospholipase C, beta 4
increases expression
ISO
methylselenic acid results in increased expression of PLCB4 mRNA
CTD
PMID:12517777
NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
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Plk1
polo-like kinase 1
affects expression decreases expression
ISO
methylselenic acid affects the expression of PLK1 mRNA methylselenic acid results in decreased expression of PLK1 mRNA
CTD
PMID:11830524 PMID:14617803
NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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Pms2
PMS1 homolog 2, mismatch repair system component
increases expression
ISO
methylselenic acid results in increased expression of PMS2 mRNA
CTD
PMID:12517777
NCBI chr12:10,676,819...10,701,161
Ensembl chr12:10,676,764...10,701,066
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Pola1
DNA polymerase alpha 1, catalytic subunit
decreases expression
ISO
methylselenic acid results in decreased expression of POLA1 mRNA
CTD
PMID:12517777
NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536
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Polr2h
RNA polymerase II, I and III subunit H
decreases expression
ISO
methylselenic acid results in decreased expression of POLR2H mRNA
CTD
PMID:18548127
NCBI chr11:80,192,017...80,197,468
Ensembl chr11:80,192,032...80,197,515
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Ppfia1
PTPRF interacting protein alpha 1
affects expression
ISO
methylselenic acid affects the expression of PPFIA1 mRNA
CTD
PMID:14617803
NCBI chr 1:199,641,277...199,718,371
Ensembl chr 1:199,641,277...199,717,277
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Ppil2
peptidylprolyl isomerase like 2
decreases expression
ISO
methylselenic acid results in decreased expression of PPIL2 mRNA
CTD
PMID:18548127
NCBI chr11:83,897,719...83,920,970
Ensembl chr11:83,897,764...83,922,144
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Ppm1b
protein phosphatase, Mg2+/Mn2+ dependent, 1B
increases expression
ISO
methylselenic acid results in increased expression of PPM1B mRNA
CTD
PMID:12517777
NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
methylselenic acid results in increased expression of PPP1R15A mRNA
CTD
PMID:28161410
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Prkar2b
protein kinase cAMP-dependent type II regulatory subunit beta
increases expression
ISO
methylselenic acid results in increased expression of PRKAR2B mRNA
CTD
PMID:18548127
NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
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Prkca
protein kinase C, alpha
increases expression
ISO
methylselenic acid results in increased expression of PRKCA mRNA
CTD
PMID:12517777
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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Prkcb
protein kinase C, beta
increases expression
ISO
methylselenic acid results in increased expression of PRKCB mRNA
CTD
PMID:18548127
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Prnp
prion protein
increases expression
ISO
methylselenic acid results in increased expression of PRNP mRNA
CTD
PMID:18548127
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Pten
phosphatase and tensin homolog
increases expression
ISO
methylselenic acid results in increased expression of PTEN mRNA
CTD
PMID:12517777
NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
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Ptges
prostaglandin E synthase
decreases expression
ISO
methylselenic acid results in decreased expression of PTGES mRNA
CTD
PMID:11830524 PMID:21669866
NCBI chr 3:14,177,892...14,189,236
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Qki
QKI, KH domain containing RNA binding
increases expression
ISO
methylselenic acid results in increased expression of QKI mRNA
CTD
PMID:18548127
NCBI chr 1:50,387,698...50,501,568
Ensembl chr 1:50,387,698...50,498,831
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Rab28
RAB28, member RAS oncogene family
increases expression
ISO
methylselenic acid results in increased expression of RAB28 mRNA
CTD
PMID:12517777
NCBI chr14:69,245,846...69,322,968
Ensembl chr14:69,245,854...69,322,967
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Rab31
RAB31, member RAS oncogene family
affects expression increases expression
ISO
methylselenic acid affects the expression of RAB31 mRNA methylselenic acid results in increased expression of RAB31 mRNA
CTD
PMID:12517777 PMID:14617803 PMID:18548127
NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
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Rabac1
Rab acceptor 1
decreases expression
ISO
methylselenic acid results in decreased expression of RABAC1 mRNA
CTD
PMID:12517777
NCBI chr 1:80,564,029...80,567,164
Ensembl chr 1:80,564,033...80,567,163
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Rad9a
RAD9 checkpoint clamp component A
increases expression
ISO
methylselenic acid results in increased expression of RAD9A mRNA
CTD
PMID:12517777
NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
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Rapgef4
Rap guanine nucleotide exchange factor 4
increases expression
ISO
methylselenic acid results in increased expression of RAPGEF4 mRNA
CTD
PMID:12517777
NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
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Rb1
RB transcriptional corepressor 1
multiple interactions
ISO
methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein]; methylselenic acid results in decreased phosphorylation of and results in increased expression of RB1 protein
CTD
PMID:17847021
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Rdh11
retinol dehydrogenase 11
affects expression
ISO
methylselenic acid affects the expression of RDH11 mRNA
CTD
PMID:14617803
NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
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Reep1
receptor accessory protein 1
increases expression
ISO
methylselenic acid results in increased expression of REEP1 mRNA
CTD
PMID:18548127
NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338
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Rfc5
replication factor C subunit 5
decreases expression
ISO
methylselenic acid results in decreased expression of RFC5 mRNA
CTD
PMID:11830524
NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
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Rgl1
ral guanine nucleotide dissociation stimulator like 1
increases expression
ISO
methylselenic acid results in increased expression of RGL1 mRNA
CTD
PMID:18548127
NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191
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Rgs10
regulator of G-protein signaling 10
increases expression
ISO
methylselenic acid results in increased expression of RGS10 mRNA
CTD
PMID:12517777
NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697
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Rhob
ras homolog family member B
affects expression
ISO
methylselenic acid affects the expression of RHOB mRNA
CTD
PMID:14617803
NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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Rims3
regulating synaptic membrane exocytosis 3
increases expression
ISO
methylselenic acid results in increased expression of RIMS3 mRNA
CTD
PMID:18548127
NCBI chr 5:134,429,092...134,468,935
Ensembl chr 5:134,435,829...134,640,489
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Rnd3
Rho family GTPase 3
increases expression
ISO
methylselenic acid results in increased expression of RND3 mRNA
CTD
PMID:18548127
NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
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Rpa2
replication protein A2
decreases expression
ISO
methylselenic acid results in decreased expression of RPA2 mRNA
CTD
PMID:12517777
NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350
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Rpia
ribose 5-phosphate isomerase A
decreases expression
ISO
methylselenic acid results in decreased expression of RPIA mRNA
CTD
PMID:18548127
NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355
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Rpl27a
ribosomal protein L27A
decreases expression
ISO
methylselenic acid results in decreased expression of RPL27A mRNA
CTD
PMID:18548127
NCBI chr 1:163,539,732...163,542,771
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Rpsa
ribosomal protein SA
decreases expression
ISO
methylselenic acid results in decreased expression of RPSA mRNA
CTD
PMID:11172735
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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Rrm1
ribonucleotide reductase catalytic subunit M1
affects expression
ISO
methylselenic acid affects the expression of RRM1 mRNA
CTD
PMID:14617803
NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
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Rrm2
ribonucleotide reductase regulatory subunit M2
affects expression
ISO
methylselenic acid affects the expression of RRM2 mRNA
CTD
PMID:14617803
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
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Rxylt1
ribitol xylosyltransferase 1
decreases expression
ISO
methylselenic acid results in decreased expression of RXYLT1 mRNA
CTD
PMID:18548127
NCBI chr 7:57,770,841...57,782,695
Ensembl chr 7:57,770,842...57,782,657
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S100a4
S100 calcium-binding protein A4
increases expression
ISO
methylselenic acid results in increased expression of S100A4 mRNA
CTD
PMID:18548127
NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
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Samd4a
sterile alpha motif domain containing 4A
increases expression
ISO
methylselenic acid results in increased expression of SAMD4 mRNA
CTD
PMID:18548127
NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380
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Sat1
spermidine/spermine N1-acetyl transferase 1
affects expression
ISO
methylselenic acid affects the expression of SAT1 mRNA
CTD
PMID:14617803
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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Scd
stearoyl-CoA desaturase
affects expression
ISO
methylselenic acid affects the expression of SCD mRNA
CTD
PMID:14617803
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Sdc2
syndecan 2
increases expression
ISO
methylselenic acid results in increased expression of SDC2 mRNA
CTD
PMID:18548127
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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Sec24d
SEC24 homolog D, COPII coat complex component
affects expression
ISO
methylselenic acid affects the expression of SEC24D mRNA
CTD
PMID:14617803
NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587
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Sema5a
semaphorin 5A
increases expression
ISO
methylselenic acid results in increased expression of SEMA5A mRNA
CTD
PMID:18548127
NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
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Serpinb5
serpin family B member 5
increases expression affects expression
ISO
methylselenic acid results in increased expression of SERPINB5 mRNA methylselenic acid affects the expression of SERPINB5 mRNA
CTD
PMID:14617803 PMID:18548127
NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
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Serpinb6a
serpin family B member 6A
decreases expression
ISO
methylselenic acid results in decreased expression of SERPINB6 mRNA
CTD
PMID:18548127
NCBI chr17:30,871,428...30,989,703
Ensembl chr17:30,871,468...31,014,427
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Serpine2
serpin family E member 2
increases expression
ISO
methylselenic acid results in increased expression of SERPINE2 mRNA
CTD
PMID:18548127
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Serpinf1
serpin family F member 1
increases expression
ISO
methylselenic acid results in increased expression of SERPINF1 mRNA
CTD
PMID:18548127
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
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Sgk1
serum/glucocorticoid regulated kinase 1
affects expression
ISO
methylselenic acid affects the expression of SGK1 mRNA
CTD
PMID:14617803
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Sh3bgr
SH3 domain binding glutamate-rich protein
increases expression
ISO
methylselenic acid results in increased expression of SH3BGR mRNA
CTD
PMID:18548127
NCBI chr11:35,503,663...35,527,853
Ensembl chr11:35,503,725...35,527,853
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Sh3bp5
SH3-domain binding protein 5
affects expression
ISO
methylselenic acid affects the expression of SH3BP5 mRNA
CTD
PMID:14617803
NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975
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Slc14a1
solute carrier family 14 member 1 (Kidd blood group)
increases expression
ISO
methylselenic acid results in increased expression of SLC14A1 mRNA
CTD
PMID:18548127
NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
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Slc16a7
solute carrier family 16 member 7
increases expression
ISO
methylselenic acid results in increased expression of SLC16A7 mRNA
CTD
PMID:18548127
NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994
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Slc19a1
solute carrier family 19 member 1
decreases expression
ISO
methylselenic acid results in decreased expression of SLC19A1 mRNA
CTD
PMID:18548127
NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
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Smad7
SMAD family member 7
increases expression
ISO
methylselenic acid results in increased expression of SMAD7 mRNA
CTD
PMID:18548127
NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
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Smarca4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
decreases expression
ISO
methylselenic acid results in decreased expression of SMARCA4 mRNA
CTD
PMID:18548127
NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
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Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
increases expression
ISO
methylselenic acid results in increased expression of SMARCD3 mRNA
CTD
PMID:18548127
NCBI chr 4:10,548,693...10,580,334
Ensembl chr 4:10,548,751...10,580,326
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Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
decreases expression
ISO
methylselenic acid results in decreased expression of SMARCE1 mRNA
CTD
PMID:12517777
NCBI chr10:84,159,270...84,180,547
Ensembl chr10:84,159,275...84,179,989
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Snai2
snail family transcriptional repressor 2
increases expression
ISO
methylselenic acid results in increased expression of SNAI2 mRNA
CTD
PMID:18548127
NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
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Snap25
synaptosome associated protein 25
increases expression
ISO
methylselenic acid results in increased expression of SNAP25 mRNA
CTD
PMID:18548127
NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
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Sncg
synuclein, gamma
increases expression
ISO
methylselenic acid results in increased expression of SNCG mRNA
CTD
PMID:18548127
NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
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Snd1
staphylococcal nuclease and tudor domain containing 1
decreases expression
ISO
methylselenic acid results in decreased expression of SND1 mRNA
CTD
PMID:18548127
NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843
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Snx1
sorting nexin 1
increases expression
ISO
methylselenic acid results in increased expression of SNX1 mRNA
CTD
PMID:18548127
NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360
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Sorbs1
sorbin and SH3 domain containing 1
increases expression
ISO
methylselenic acid results in increased expression of SORBS1 mRNA
CTD
PMID:18548127
NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
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Sp1
Sp1 transcription factor
multiple interactions
ISO
methylselenic acid inhibits the reaction [SP1 protein binds to BIRC5 promoter]
CTD
PMID:17876054
NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
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Spdef
SAM pointed domain containing ets transcription factor
increases expression
ISO
methylselenic acid results in increased expression of SPDEF protein
CTD
PMID:18567002
NCBI chr20:5,771,434...5,786,793
Ensembl chr20:5,771,441...5,785,893
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Sptan1
spectrin, alpha, non-erythrocytic 1
increases expression
ISO
methylselenic acid results in increased expression of SPTAN1 mRNA
CTD
PMID:18548127
NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
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Srp19
signal recognition particle 19
decreases expression
ISO
methylselenic acid results in decreased expression of SRP19 mRNA
CTD
PMID:18548127
NCBI chr18:25,931,734...25,937,974
Ensembl chr18:25,931,589...25,938,017
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Ssbp2
single-stranded DNA binding protein 2
increases expression
ISO
methylselenic acid results in increased expression of SSBP2 mRNA
CTD
PMID:18548127
NCBI chr 2:22,650,488...22,933,696
Ensembl chr 2:22,651,258...22,933,696
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ST7
suppression of tumorigenicity 7
decreases expression affects expression
ISO
methylselenic acid results in decreased expression of ST7 mRNA methylselenic acid affects the expression of ST7 mRNA
CTD
PMID:14617803 PMID:18548127
NCBI chr 4:46,041,655...46,289,745
Ensembl chr 4:46,042,236...46,289,740
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Stom
stomatin
increases expression
ISO
methylselenic acid results in increased expression of STOM mRNA
CTD
PMID:18548127
NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:18,644,378...18,667,354
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Stx12
syntaxin 12
increases expression
ISO
methylselenic acid results in increased expression of STX12 mRNA
CTD
PMID:18548127
NCBI chr 5:145,062,978...145,092,423
Ensembl chr 5:145,063,587...145,092,377
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Stx1a
syntaxin 1A
affects expression
ISO
methylselenic acid affects the expression of STX1A mRNA
CTD
PMID:14617803
NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
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Stx2
syntaxin 2
increases expression
ISO
methylselenic acid results in increased expression of STX2 mRNA
CTD
PMID:18548127
NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751
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Svil
supervillin
increases expression
ISO
methylselenic acid results in increased expression of SVIL mRNA
CTD
PMID:18548127
NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
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Tacstd2
tumor-associated calcium signal transducer 2
decreases expression
ISO
methylselenic acid results in decreased expression of TACSTD2 mRNA
CTD
PMID:18548127
NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
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Tarbp2
Tarbp2 subunit of RISC loading complex
decreases expression
ISO
methylselenic acid results in decreased expression of TARBP2 mRNA
CTD
PMID:18548127
NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314
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Tbl1x
transducin (beta)-like 1 X-linked
increases expression
ISO
methylselenic acid results in increased expression of TBL1X mRNA
CTD
PMID:18548127
NCBI chr X:41,574,558...41,731,117
Ensembl chr X:41,576,047...41,731,101
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Tbxas1
thromboxane A synthase 1
decreases expression
ISO
methylselenic acid results in decreased expression of TBXAS1 mRNA
CTD
PMID:21669866
NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
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Tcn2
transcobalamin 2
increases expression
ISO
methylselenic acid results in increased expression of TCN2 mRNA
CTD
PMID:18548127
NCBI chr14:78,813,343...78,828,549
Ensembl chr14:78,813,343...78,828,489
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Tff1
trefoil factor 1
multiple interactions
ISO
methylselenic acid inhibits the reaction [afimoxifene results in increased expression of TFF1 mRNA]; methylselenic acid inhibits the reaction [Estradiol results in increased expression of TFF1 mRNA]
CTD
PMID:16093440 PMID:16155795
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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Tgfb1
transforming growth factor, beta 1
increases expression
ISO
methylselenic acid results in increased expression of TGFB1 mRNA
CTD
PMID:12517777
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfb2
transforming growth factor, beta 2
increases expression
ISO
methylselenic acid results in increased expression of TGFB2 mRNA
CTD
PMID:18548127
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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Tgfbr2
transforming growth factor, beta receptor 2
increases expression
ISO
methylselenic acid results in increased expression of TGFBR2 mRNA
CTD
PMID:18548127
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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Tgfbr3
transforming growth factor beta receptor 3
increases expression
ISO
methylselenic acid results in increased expression of TGFBR3 mRNA
CTD
PMID:12517777 PMID:18548127
NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
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Tle2
TLE family member 2, transcriptional corepressor
increases expression
ISO
methylselenic acid results in increased expression of TLE2 mRNA
CTD
PMID:18548127
NCBI chr 7:8,119,049...8,135,385
Ensembl chr 7:8,119,053...8,134,306
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Tlr2
toll-like receptor 2
increases expression
ISO
methylselenic acid results in increased expression of TLR2 mRNA
CTD
PMID:12517777
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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Tnfaip3
TNF alpha induced protein 3
affects expression
ISO
methylselenic acid affects the expression of TNFAIP3 mRNA
CTD
PMID:14617803
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tnfrsf25
TNF receptor superfamily member 25
increases expression
ISO
methylselenic acid results in increased expression of TNFRSF25 mRNA
CTD
PMID:11830524
NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
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Top2a
DNA topoisomerase II alpha
affects expression
ISO
methylselenic acid affects the expression of TOP2A mRNA
CTD
PMID:14617803
NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
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Tor1aip1
torsin 1A interacting protein 1
increases expression
ISO
methylselenic acid results in increased expression of TOR1AIP1 mRNA
CTD
PMID:18548127
NCBI chr13:68,196,681...68,226,121
Ensembl chr13:68,196,681...68,225,862
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Tpm1
tropomyosin 1
increases expression
ISO
methylselenic acid results in increased expression of TPM1 mRNA
CTD
PMID:18548127
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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Trib1
tribbles pseudokinase 1
decreases expression
ISO
methylselenic acid results in decreased expression of TRIB1 mRNA
CTD
PMID:18548127
NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
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Trim14
tripartite motif-containing 14
decreases expression
ISO
methylselenic acid results in decreased expression of TRIM14 mRNA
CTD
PMID:18548127
NCBI chr 5:60,800,032...60,825,481
Ensembl chr 5:60,800,032...60,824,858
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Ttk
Ttk protein kinase
decreases expression
ISO
methylselenic acid results in decreased expression of TTK mRNA
CTD
PMID:18548127
NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
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Txnrd1
thioredoxin reductase 1
increases metabolic processing
ISO
TXNRD1 protein results in increased metabolism of methylselenic acid
CTD
PMID:11782468
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Tyms
thymidylate synthetase
decreases expression affects expression
ISO
methylselenic acid results in decreased expression of TYMS mRNA methylselenic acid affects the expression of TYMS mRNA
CTD
PMID:12517777 PMID:14617803
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Uck2
uridine-cytidine kinase 2
decreases expression
ISO
methylselenic acid results in decreased expression of UCK2 mRNA
CTD
PMID:18548127
NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352
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Ugdh
UDP-glucose 6-dehydrogenase
affects expression
ISO
methylselenic acid affects the expression of UGDH mRNA
CTD
PMID:14617803
NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
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Utrn
utrophin
decreases expression
ISO
methylselenic acid results in decreased expression of UTRN mRNA
CTD
PMID:18548127
NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
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Vamp3
vesicle-associated membrane protein 3
increases expression
ISO
methylselenic acid results in increased expression of VAMP3 mRNA
CTD
PMID:18548127
NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751
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Vdr
vitamin D receptor
affects expression
ISO
methylselenic acid affects the expression of VDR mRNA
CTD
PMID:16928829
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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Vegfc
vascular endothelial growth factor C
decreases expression
ISO
methylselenic acid results in decreased expression of VEGFC mRNA
CTD
PMID:12517777
NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
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Vim
vimentin
increases expression
ISO
methylselenic acid results in increased expression of VIM mRNA
CTD
PMID:18548127
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Wasf1
WASP family member 1
affects expression
ISO
methylselenic acid affects the expression of WASF1 mRNA
CTD
PMID:14617803
NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996
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Wnt7a
Wnt family member 7A
decreases expression
ISO
methylselenic acid results in decreased expression of WNT7A mRNA
CTD
PMID:12517777
NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981
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Wsb2
WD repeat and SOCS box-containing 2
decreases expression
ISO
methylselenic acid results in decreased expression of WSB2 mRNA
CTD
PMID:18548127
NCBI chr12:39,217,645...39,238,667
Ensembl chr12:39,217,648...39,238,640
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Xbp1
X-box binding protein 1
increases splicing
ISO
methylselenic acid results in increased splicing of XBP1 mRNA
CTD
PMID:16205645 PMID:28161410
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
decreases expression
ISO
methylselenic acid results in decreased expression of YWHAE mRNA
CTD
PMID:18548127
NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
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Zcchc24
zinc finger CCHC-type containing 24
increases expression
ISO
methylselenic acid results in increased expression of ZCCHC24 mRNA
CTD
PMID:18548127
NCBI chr16:1,274,544...1,326,664
Ensembl chr16:1,274,548...1,326,696
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Zfp110
zinc finger protein 110
increases expression
ISO
methylselenic acid results in increased expression of ZNF274 mRNA
CTD
PMID:12517777
NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086
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Zfp217
zinc finger protein 217
increases expression
ISO
methylselenic acid results in increased expression of ZNF217 mRNA
CTD
PMID:12517777
NCBI chr 3:158,890,464...158,931,148
Ensembl chr 3:158,892,265...158,913,040
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Zfp24
zinc finger protein 24
decreases expression
ISO
methylselenic acid results in decreased expression of ZNF24 mRNA
CTD
PMID:18548127
NCBI chr18:15,295,687...15,307,319
Ensembl chr18:15,298,290...15,306,799
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Zfp267
zinc finger protein 267
increases expression
ISO
methylselenic acid results in increased expression of ZNF267 mRNA
CTD
PMID:12517777
NCBI chr 2:119,017,244...119,035,885
Ensembl chr 2:119,017,285...119,031,900
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Zfp458
zinc finger protein 458
decreases expression
ISO
methylselenic acid results in decreased expression of ZNF43 mRNA
CTD
PMID:18548127
NCBI chr 2:84,661,150...84,705,631
Ensembl chr 2:84,693,186...84,702,558
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