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ONTOLOGY REPORT - ANNOTATIONS


Term:metacetamol
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Accession:CHEBI:76987 term browser browse the term
Definition:A derivative of phenol which has an acetamido substituent located meta to the phenolic -OH group. It is a non-toxic regioisomer of paracetamol with analgesic properties, but has never been marketed as a drug.
Synonyms:exact_synonym: N-(3-hydroxyphenyl)acetamide
 related_synonym: 3-(acetylamino)-1-hydroxybenzene;   3-(acetylamino)phenol;   3-acetamidophenol;   3-hydroxyacetanilide;   Formula=C8H9NO2;   InChI=1S/C8H9NO2/c1-6(10)9-7-3-2-4-8(11)5-7/h2-5,11H,1H3,(H,9,10);   InChIKey=QLNWXBAGRTUKKI-UHFFFAOYSA-N;   N-acetyl-m-aminophenol;   SMILES=CC(=O)Nc1cccc(O)c1;   m-(acetylamino)phenol;   m-acetamidophenol;   m-hydroxyacetanilide;   metacetamolum
 xref: CAS:621-42-1 "ChemIDplus";   CAS:621-42-1 "NIST Chemistry WebBook";   LINCS:LSM-19995
 xref_mesh: MESH:C026137
 xref: PMID:10892726 "Europe PMC";   PMID:24038040 "Europe PMC";   Reaxys:907998 "Reaxys"


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metacetamol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Actg1 actin, gamma 1 JBrowse link 10 109,518,429 109,521,288 RGD:6480464
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:6480464
G Akap12 A-kinase anchoring protein 12 JBrowse link 1 40,816,130 40,906,582 RGD:6480464
G Akr1d1 aldo-keto reductase family 1, member D1 JBrowse link 4 65,110,706 65,143,930 RGD:6480464
G Anp32a acidic nuclear phosphoprotein 32 family member A JBrowse link 8 67,295,578 67,333,075 RGD:6480464
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:6480464
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:6480464
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:6480464
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:6480464
G Baat bile acid CoA:amino acid N-acyltransferase JBrowse link 5 64,768,397 64,777,368 RGD:6480464
G Bag3 Bcl2-associated athanogene 3 JBrowse link 1 199,941,258 199,965,191 RGD:6480464
G Bbox1 gamma-butyrobetaine hydroxylase 1 JBrowse link 3 101,425,684 101,474,848 RGD:6480464
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:6480464
G Btg2 BTG anti-proliferation factor 2 JBrowse link 13 50,913,185 50,916,944 RGD:6480464
G Btg3 BTG anti-proliferation factor 3 JBrowse link 11 16,873,642 16,889,100 RGD:6480464
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:6480464
G Camp cathelicidin antimicrobial peptide JBrowse link 8 117,930,557 117,932,371 RGD:6480464
G Cbr3 carbonyl reductase 3 JBrowse link 11 33,909,417 33,917,674 RGD:6480464
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:6480464
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:6480464
G Cdc6 cell division cycle 6 JBrowse link 10 86,819,477 86,833,301 RGD:6480464
G Chia chitinase, acidic JBrowse link 2 208,750,348 208,797,388 RGD:6480464
G Cldn3 claudin 3 JBrowse link 12 21,831,341 21,832,813 RGD:6480464
G Cln8 CLN8, transmembrane ER and ERGIC protein JBrowse link 16 79,828,321 79,838,212 RGD:6480464
G Cnmd chondromodulin JBrowse link 15 61,923,291 61,947,840 RGD:6480464
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 JBrowse link 1 83,626,639 83,638,154 RGD:6480464
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:6480464
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 2 102,701,903 102,871,257 RGD:6480464
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 JBrowse link 8 130,548,418 130,550,388 RGD:6480464
G Dbp D-box binding PAR bZIP transcription factor JBrowse link 1 101,687,896 101,692,845 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:6480464
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 JBrowse link 19 24,747,178 24,750,919 RGD:6480464
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:6480464
G Dusp14 dual specificity phosphatase 14 JBrowse link 10 71,363,688 71,383,602 RGD:6480464
G Dusp4 dual specificity phosphatase 4 JBrowse link 16 61,080,767 61,090,973 RGD:6480464
G Dusp6 dual specificity phosphatase 6 JBrowse link 7 41,475,163 41,479,393 RGD:6480464
G Dusp8 dual specificity phosphatase 8 JBrowse link 1 215,030,429 215,043,111 RGD:6480464
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:6480464
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:6480464
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:6480464
G Fgf4 fibroblast growth factor 4 JBrowse link 1 218,024,537 218,029,539 RGD:6480464
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:6480464
G Fmo3 flavin containing dimethylaniline monoxygenase 3 JBrowse link 13 80,837,418 80,856,214 RGD:6480464
G Fosl1 FOS like 1, AP-1 transcription factor subunit JBrowse link 1 220,826,560 220,835,066 RGD:6480464
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:6480464
G G0s2 G0/G1switch 2 JBrowse link 13 112,004,140 112,005,052 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 16 20,555,395 20,557,978 RGD:6480464
G Gmnn geminin, DNA replication inhibitor JBrowse link 17 42,302,523 42,310,783 RGD:6480464
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:6480464
G Gsta5 glutathione S-transferase alpha 5 JBrowse link 8 85,553,659 85,564,914 RGD:6480464
G Gsta6 glutathione S-transferase alpha 6 JBrowse link 9 27,475,273 27,533,939 RGD:6480464
G Gys2 glycogen synthase 2 JBrowse link 4 176,638,632 176,679,805 RGD:6480464
G Hal histidine ammonia lyase JBrowse link 7 34,326,087 34,356,413 RGD:6480464
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:6480464
G Hbegf heparin-binding EGF-like growth factor JBrowse link 18 29,330,302 29,340,185 RGD:6480464
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:6480464
G Hsph1 heat shock protein family H (Hsp110) member 1 JBrowse link 12 6,322,685 6,341,898 RGD:6480464
G Ifrd1 interferon-related developmental regulator 1 JBrowse link 6 60,132,025 60,151,354 RGD:6480464
G Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 9 80,154,230 80,166,813 RGD:6480464
G Inhbe inhibin subunit beta E JBrowse link 7 70,641,423 70,642,848 RGD:6480464
G Itpka inositol-trisphosphate 3-kinase A JBrowse link 3 111,545,007 111,553,605 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Lrp4 LDL receptor related protein 4 JBrowse link 3 80,362,643 80,416,684 RGD:6480464
G Map3k14 mitogen-activated protein kinase kinase kinase 14 JBrowse link 10 91,303,428 91,353,601 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mapk6 mitogen-activated protein kinase 6 JBrowse link 8 82,328,013 82,351,108 RGD:6480464
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:6480464
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:6480464
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:6480464
G Mov10 Mov10 RISC complex RNA helicase JBrowse link 2 207,277,088 207,301,245 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Myo18b myosin XVIIIb JBrowse link 12 49,761,100 49,979,745 RGD:6480464
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:6480464
G Neurod4 neuronal differentiation 4 JBrowse link 7 9,699,964 9,712,067 RGD:6480464
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:6480464
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:6480464
G Pde6c phosphodiesterase 6C JBrowse link 1 256,822,099 256,885,879 RGD:6480464
G Per3 period circadian regulator 3 JBrowse link 5 168,088,126 168,123,482 RGD:6480464
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 JBrowse link X 23,092,143 23,145,923 RGD:6480464
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 JBrowse link 17 70,632,778 70,713,736 RGD:6480464
G Pglyrp1 peptidoglycan recognition protein 1 JBrowse link 1 79,790,879 79,796,064 RGD:6480464
G Plpp3 phospholipid phosphatase 3 JBrowse link 5 124,690,214 124,765,499 RGD:6480464
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A JBrowse link 1 87,224,683 87,232,842 RGD:6480464
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:6480464
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:6480464
G Psmb10 proteasome 20S subunit beta 10 JBrowse link 19 37,909,543 37,912,027 RGD:6480464
G Rbl2 RB transcriptional corepressor like 2 JBrowse link 19 17,300,088 17,346,865 RGD:6480464
G Rgs12 regulator of G-protein signaling 12 JBrowse link 14 80,975,239 81,069,519 RGD:6480464
G Rhbg Rh family B glycoprotein JBrowse link 2 187,610,081 187,622,408 RGD:6480464
G S100a6 S100 calcium binding protein A6 JBrowse link 2 190,007,013 190,008,512 RGD:6480464
G S100a8 S100 calcium binding protein A8 JBrowse link 2 190,073,239 190,074,333 RGD:6480464
G Selenom selenoprotein M JBrowse link 14 83,752,393 83,754,975 RGD:6480464
G Shpk sedoheptulokinase JBrowse link 10 59,765,328 59,789,676 RGD:6480464
G Slc1a2 solute carrier family 1 member 2 JBrowse link 3 92,518,679 92,665,731 RGD:6480464
G Slc25a13 solute carrier family 25 member 13 JBrowse link 4 31,134,165 31,757,006 RGD:6480464
G Slc2a2 solute carrier family 2 member 2 JBrowse link 2 114,413,427 114,445,418 RGD:6480464
G Slc2a3 solute carrier family 2 member 3 JBrowse link 4 155,549,991 155,626,018 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 4 175,969,549 176,026,227 RGD:6480464
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sprr1a small proline-rich protein 1A JBrowse link 2 192,669,143 192,671,059 RGD:6480464
G Sprr1b small proline-rich protein 1B JBrowse link 2 192,622,972 192,624,848 RGD:6480464
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:6480464
G Tnfrsf12a TNF receptor superfamily member 12A JBrowse link 10 12,995,904 12,997,930 RGD:6480464
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:6480464
G Usp2 ubiquitin specific peptidase 2 JBrowse link 8 48,403,985 48,432,525 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
G Zfand2a zinc finger AN1-type containing 2A JBrowse link 12 17,252,093 17,263,477 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        pharmacological role 18684
          analgesic 13037
            non-narcotic analgesic 11941
              metacetamol 113
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                acetamides 11569
                                                  metacetamol 113
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.