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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.4.23.* (aspartic endopeptidase) inhibitor
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Accession:CHEBI:76885 term browser browse the term
Definition:An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any aspartic endopeptidase (EC 3.4.23.*).
Synonyms:related_synonym: EC 3.4.23.* (aspartic endopeptidases) inhibitor;   EC 3.4.23.* inhibitor;   EC 3.4.23.* inhibitors;   aspartic endopeptidase (EC 3.4.23.*) inhibitors;   aspartic endopeptidases (EC 3.4.23.*) inhibitors


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pepstatin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LTA4H leukotriene A4 hydrolase decreases activity EXP pepstatin results in decreased activity of LTA4H protein CTD PMID:21670530 NCBI chr 5:87,486,552...87,518,520
Ensembl chr 5:87,486,512...87,518,515
JBrowse link
G PGA5 pepsinogen 5, group I (pepsinogen A) decreases activity EXP pepstatin analog results in decreased activity of PGA5 protein CTD PMID:1478780 NCBI chr 2:10,244,300...10,252,644
Ensembl chr 2:10,244,187...10,252,680
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 885
    role 865
      biological role 865
        biochemical role 729
          enzyme inhibitor 326
            EC 3.* (hydrolase) inhibitor 270
              EC 3.4.* (hydrolases acting on peptide bond) inhibitor 21
                EC 3.4.23.* (aspartic endopeptidase) inhibitor 2
                  EC 3.4.23.15 (renin) inhibitor + 0
                  EC 3.4.23.46 (memapsin 2) inhibitor + 0
                  pepstatin A 2
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