CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: EC 4.1.* (C-C lyase) inhibitor
Accession: CHEBI:76711
browse the term
Definition: A lyase inhibitor which inhibits the action of a C-C lyase (EC 4.1.*.*).
Synonyms: related_synonym: C-C lyase inhibitor; C-C lyase inhibitors; EC 4.1.* (C-C lyase) inhibitors; EC 4.1.* inhibitor; EC 4.1.* inhibitors
G
Comt
catechol-O-methyltransferase
increases methylation
ISO EXP
COMT protein results in increased methylation of Benserazide
CTD
PMID:11160877
NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
G
Drd1
dopamine receptor D1
multiple interactions
EXP
[Oxidopamine co-treated with levodopa methyl ester] promotes the reaction [Benserazide results in increased expression of DRD1 protein]
CTD
PMID:19399396
NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
G
Drd2
dopamine receptor D2
multiple interactions
EXP
[Oxidopamine co-treated with levodopa methyl ester] inhibits the reaction [Benserazide results in increased expression of DRD2 protein]
CTD
PMID:19399396
NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
G
Comt
catechol-O-methyltransferase
increases methylation
ISO EXP
COMT protein results in increased methylation of Carbidopa
CTD
PMID:11160877
NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
G
Fasn
fatty acid synthase
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased activity of FASN protein]
CTD
PMID:29653099
NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased activity of G6PD protein]
CTD
PMID:29653099
NCBI chr X:156,274,800...156,293,935
Ensembl chr X:156,274,800...156,293,926
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased activity of GPT protein]
CTD
PMID:29653099
NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
G
Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]
CTD
PMID:29653099
NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
G
Srebf2
sterol regulatory element binding transcription factor 2
multiple interactions
ISO
herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF2 mRNA]
CTD
PMID:29653099
NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
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