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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 5.3.* (intramolecular oxidoreductase) inhibitor
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Accession:CHEBI:76694 term browser browse the term
Definition:An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*).
Synonyms:related_synonym: EC 5.3.* (intramolecular oxidoreductase) inhibitors;   intramolecular oxidoreductase inhibitor;   intramolecular oxidoreductase inhibitors



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amorolfine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 chemokine (C-C motif) ligand 5 multiple interactions ISO amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA] CTD PMID:23688403 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 multiple interactions ISO amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA]; amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 protein] CTD PMID:24471457 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA] CTD PMID:23688403 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Il4 interleukin 4 multiple interactions ISO 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; amorolfine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone] CTD PMID:23688403 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO amorolfine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,319,589...24,351,684
Ensembl chr 5:24,319,589...24,351,604
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein] CTD PMID:23688403 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO amorolfine inhibits the reaction [Biological Products results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:24471457 NCBI chr 1:52,119,438...52,161,865
Ensembl chr 1:52,119,440...52,161,865
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein] CTD PMID:23688403 NCBI chr18:32,815,383...32,819,799
Ensembl chr18:32,815,383...32,819,797
JBrowse link
copper(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase decreases expression ISO cupric chloride results in decreased expression of AASDHPPT mRNA CTD PMID:17211630 NCBI chr 9:4,294,793...4,309,617
Ensembl chr 9:4,294,793...4,309,471
JBrowse link
G Abcf3 ATP-binding cassette, sub-family F (GCN20), member 3 increases expression ISO cupric chloride results in increased expression of ABCF3 mRNA CTD PMID:17211630 NCBI chr16:20,548,556...20,561,603
Ensembl chr16:20,548,577...20,561,379
JBrowse link
G Abhd4 abhydrolase domain containing 4 increases expression ISO cupric chloride results in increased expression of ABHD4 mRNA CTD PMID:17211630 NCBI chr14:54,254,129...54,269,169
Ensembl chr14:54,254,188...54,270,637
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO cupric chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ACHE protein]
Carnosine inhibits the reaction [cupric chloride results in decreased activity of ACHE protein]
CTD PMID:24799335 PMID:32745495 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Aco1 aconitase 1 decreases expression EXP cupric chloride results in decreased expression of ACO1 protein CTD PMID:29617964 NCBI chr 4:40,143,265...40,199,009
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Actb actin, beta increases expression EXP cupric chloride results in increased expression of ACTB protein CTD PMID:29617964 NCBI chr 5:142,903,115...142,907,976
Ensembl chr 5:142,903,115...142,906,754
JBrowse link
G Adrm1 adhesion regulating molecule 1 increases expression ISO cupric chloride results in increased expression of ADRM1 mRNA CTD PMID:17211630 NCBI chr 2:180,171,588...180,176,283
Ensembl chr 2:180,171,485...180,176,286
JBrowse link
G Ahsg alpha-2-HS-glycoprotein decreases expression ISO cupric chloride results in decreased expression of AHSG mRNA CTD PMID:17211630 NCBI chr16:22,892,015...22,899,451
Ensembl chr16:22,891,277...22,899,449
JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) increases expression EXP cupric chloride results in increased expression of AKR1A1 protein CTD PMID:29617964 NCBI chr 4:116,636,510...116,651,674
Ensembl chr 4:116,636,510...116,651,680
JBrowse link
G Alb albumin multiple interactions ISO ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein] CTD PMID:11820775 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases expression EXP cupric chloride results in increased expression of ALDH1L1 mRNA CTD PMID:17211630 NCBI chr 6:90,550,768...90,599,171
Ensembl chr 6:90,486,427...90,600,203
JBrowse link
G Aldoa aldolase A, fructose-bisphosphate increases expression EXP cupric chloride results in increased expression of ALDOA protein CTD PMID:29617964 NCBI chr 7:126,795,234...126,800,994
Ensembl chr 7:126,795,234...126,800,751
Ensembl chr 7:126,795,234...126,800,751
JBrowse link
G Aldoc aldolase C, fructose-bisphosphate decreases expression EXP cupric chloride results in decreased expression of ALDOC protein CTD PMID:29617964 NCBI chr11:78,323,073...78,327,781
Ensembl chr11:78,322,968...78,327,781
JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase decreases activity ISO cupric chloride results in decreased activity of ALKBH2 protein CTD PMID:28926697 NCBI chr 5:114,123,926...114,131,233
Ensembl chr 5:114,123,926...114,128,218
JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase decreases activity ISO cupric chloride results in decreased activity of ALKBH3 protein CTD PMID:28926697 NCBI chr 2:93,980,624...94,010,824
Ensembl chr 2:93,980,550...94,010,807
JBrowse link
G Ankrd1 ankyrin repeat domain 1 (cardiac muscle) increases expression ISO cupric chloride results in increased expression of ANKRD1 mRNA CTD PMID:17211630 NCBI chr19:36,111,965...36,119,844
Ensembl chr19:36,111,961...36,120,099
JBrowse link
G Anpep alanyl (membrane) aminopeptidase decreases expression ISO cupric chloride results in decreased expression of ANPEP mRNA CTD PMID:17211630 NCBI chr 7:79,821,803...79,848,210
Ensembl chr 7:79,821,803...79,861,059
JBrowse link
G Apom apolipoprotein M increases expression EXP cupric chloride results in increased expression of APOM mRNA CTD PMID:17211630 NCBI chr17:35,128,997...35,131,801
Ensembl chr17:35,128,997...35,132,050
JBrowse link
G App amyloid beta (A4) precursor protein increases expression
multiple interactions
ISO
EXP
cupric chloride results in increased expression of APP mRNA; cupric chloride results in increased expression of APP protein
cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form
cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form; PP242 inhibits the reaction [cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form]
CTD PMID:22542740 PMID:32512069 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766
JBrowse link
G Ar androgen receptor multiple interactions ISO [Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein CTD PMID:19789329 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein] CTD PMID:30768131 NCBI chr 2:73,816,509...73,892,677
Ensembl chr 2:73,816,509...73,892,639
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] CTD PMID:20920558 NCBI chr15:80,255,184...80,257,545
Ensembl chr15:80,255,184...80,257,541
JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions ISO cupric chloride results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Atox1 antioxidant 1 copper chaperone multiple interactions ISO [cupric chloride results in increased abundance of Copper] which results in increased expression of ATOX1 mRNA; ATOX1 protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper] CTD PMID:32278528 NCBI chr11:55,446,637...55,461,208
Ensembl chr11:55,446,641...55,461,239
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide increases transport
increases expression
multiple interactions
decreases glutathionylation
affects localization
ISO
EXP
ATP7A protein results in increased transport of cupric chloride
cupric chloride results in increased expression of ATP7A protein
cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein]; cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]
cupric chloride results in decreased glutathionylation of ATP7A protein
cupric chloride affects the localization of ATP7A protein
Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
ATP7A protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7A protein results in decreased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]]; cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]
CTD PMID:11092760 PMID:16317117 PMID:17009961 PMID:20566629 PMID:21242307 More... NCBI chr  X:106,027,224...106,128,161
Ensembl chr  X:106,027,276...106,124,926
JBrowse link
G Atp7b ATPase, Cu++ transporting, beta polypeptide decreases response to substance
affects localization
multiple interactions
ISO ATP7B protein results in decreased susceptibility to cupric chloride
cupric chloride affects the localization of ATP7B protein
ATP7B protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7B protein results in increased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
CTD PMID:10728692 PMID:16799059 PMID:21242307 PMID:24343273 PMID:32278528 NCBI chr 8:21,992,783...22,060,074
Ensembl chr 8:21,992,785...22,060,305
JBrowse link
G Bace1 beta-site APP cleaving enzyme 1 increases expression ISO cupric chloride results in increased expression of BACE1 mRNA; cupric chloride results in increased expression of BACE1 protein CTD PMID:22542740 NCBI chr 9:45,838,545...45,862,484
Ensembl chr 9:45,838,580...45,864,399
JBrowse link
G Bag3 BCL2-associated athanogene 3 increases expression ISO cupric chloride results in increased expression of BAG3 mRNA CTD PMID:17211630 NCBI chr 7:128,523,583...128,546,981
Ensembl chr 7:128,523,616...128,546,981
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
EXP
ISO
cupric chloride results in increased expression of BAX protein
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of BAX protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]
CTD PMID:21035945 PMID:22239859 PMID:23313662 PMID:24170445 PMID:29803612 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
ISO
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein]
[Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein
cupric chloride results in decreased expression of BCL2 protein
CTD PMID:20920558 PMID:21911303 PMID:23313662 PMID:24170445 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression EXP cupric chloride results in decreased expression of BCL2L1 protein CTD PMID:23313662 PMID:24170445 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO cupric chloride results in increased expression of BID mRNA CTD PMID:17211630 NCBI chr 6:120,893,119...120,917,062
Ensembl chr 6:120,891,930...120,916,853
JBrowse link
G Blvrb biliverdin reductase B (flavin reductase (NADPH)) increases expression ISO cupric chloride results in increased expression of BLVRB mRNA CTD PMID:17211630 NCBI chr 7:27,447,978...27,465,981
Ensembl chr 7:27,447,978...27,466,144
JBrowse link
G C1qtnf4 C1q and tumor necrosis factor related protein 4 increases expression EXP cupric chloride results in increased expression of C1QTNF4 mRNA CTD PMID:17211630 NCBI chr 2:90,882,788...90,890,526
Ensembl chr 2:90,885,860...90,890,525
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
decreases activity
ISO
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP3 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]
cupric chloride results in increased expression of CASP3 protein
cupric chloride results in increased activity of CASP3 protein
cupric chloride results in decreased activity of CASP3 protein
CTD PMID:11239917 PMID:18056745 PMID:20920558 PMID:21035945 PMID:22954531 More... NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp7 caspase 7 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein]
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]
CTD PMID:20920558 PMID:21035945 NCBI chr19:56,396,833...56,442,348
Ensembl chr19:56,397,129...56,442,344
JBrowse link
G Casp8 caspase 8 increases expression EXP cupric chloride results in increased expression of CASP8 protein CTD PMID:23313662 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein]
cupric chloride results in increased expression of CASP9 protein
CTD PMID:20920558 PMID:23313662 PMID:24170445 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO Carnosine inhibits the reaction [cupric chloride results in decreased activity of CAT protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] CTD PMID:29803612 PMID:32745495 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO cupric chloride results in increased expression of CCN1 mRNA CTD PMID:17211630 NCBI chr 3:145,646,971...145,649,985
Ensembl chr 3:145,646,976...145,649,981
JBrowse link
G Ccs copper chaperone for superoxide dismutase multiple interactions ISO cupric chloride results in increased degradation of and results in decreased expression of CCS protein CTD PMID:16531609 NCBI chr19:4,825,366...4,839,356
Ensembl chr19:4,825,366...4,839,332
JBrowse link
G Cd63 CD63 antigen decreases expression ISO cupric chloride results in decreased expression of CD63 mRNA CTD PMID:17211630 NCBI chr10:128,896,231...128,912,822
Ensembl chr10:128,900,989...128,912,822
JBrowse link
G Cdc34 cell division cycle 34 affects expression ISO cupric chloride affects the expression of CDC34 mRNA CTD PMID:17211630 NCBI chr10:79,682,193...79,688,398
Ensembl chr10:79,682,195...79,688,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) affects expression ISO cupric chloride affects the expression of CDKN1A mRNA CTD PMID:17211630 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B affects expression EXP cupric chloride affects the expression of CDKN1B protein CTD PMID:23313662 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 increases expression ISO cupric chloride results in increased expression of CHORDC1 mRNA CTD PMID:17211630 NCBI chr 9:18,292,267...18,314,000
Ensembl chr 9:18,292,125...18,317,442
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression EXP cupric chloride results in decreased expression of CKMT2 protein CTD PMID:29617964 NCBI chr13:91,853,386...91,876,923
Ensembl chr13:91,853,387...91,876,885
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO cupric chloride results in increased expression of CKS2 mRNA CTD PMID:17211630 NCBI chr13:51,645,232...51,650,662
Ensembl chr13:51,645,232...51,650,660
JBrowse link
G Clcn6 chloride channel, voltage-sensitive 6 increases expression ISO cupric chloride results in increased expression of CLCN6 mRNA CTD PMID:17211630 NCBI chr 4:148,004,259...148,038,813
Ensembl chr 4:148,004,259...148,038,821
JBrowse link
G Clcn7 chloride channel, voltage-sensitive 7 affects expression ISO cupric chloride affects the expression of CLCN7 mRNA CTD PMID:17211630 NCBI chr17:25,133,378...25,162,103
Ensembl chr17:25,133,391...25,162,104
JBrowse link
G Cldnd1 claudin domain containing 1 increases expression ISO cupric chloride results in increased expression of CLDND1 mRNA CTD PMID:17211630 NCBI chr16:58,727,910...58,734,247
Ensembl chr16:58,727,910...58,734,251
JBrowse link
G Clu clusterin multiple interactions
increases expression
ISO
EXP
cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
cupric chloride results in increased expression of CLU mRNA
CTD PMID:17211630 PMID:21242307 NCBI chr14:65,968,483...65,981,548
Ensembl chr14:65,968,483...65,981,547
JBrowse link
G Commd1 COMM domain containing 1 decreases response to substance
multiple interactions
decreases expression
ISO COMMD1 protein results in decreased susceptibility to cupric chloride
cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]
[COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein
cupric chloride results in decreased expression of COMMD1 mRNA; cupric chloride results in decreased expression of COMMD1 protein
CTD PMID:17211630 PMID:24691167 PMID:25007851 NCBI chr11:22,899,728...22,984,539
Ensembl chr11:22,896,136...22,982,382
JBrowse link
G Commd10 COMM domain containing 10 decreases expression ISO cupric chloride results in decreased expression of COMMD10 mRNA CTD PMID:17211630 NCBI chr18:46,958,819...47,087,995
Ensembl chr18:46,958,816...47,234,284
JBrowse link
G Commd2 COMM domain containing 2 decreases expression ISO cupric chloride results in decreased expression of COMMD2 mRNA CTD PMID:17211630 NCBI chr 3:57,644,349...57,651,684
Ensembl chr 3:57,644,349...57,651,715
JBrowse link
G Commd3 COMM domain containing 3 decreases expression ISO cupric chloride results in decreased expression of COMMD3 mRNA CTD PMID:17211630 NCBI chr 2:18,672,435...18,676,231
Ensembl chr 2:18,672,384...18,676,231
JBrowse link
G Commd4 COMM domain containing 4 decreases expression ISO cupric chloride results in decreased expression of COMMD4 mRNA CTD PMID:17211630 NCBI chr 9:57,155,035...57,158,349
Ensembl chr 9:57,155,035...57,158,331
JBrowse link
G Commd5 COMM domain containing 5 decreases expression ISO cupric chloride results in decreased expression of COMMD5 mRNA CTD PMID:17211630 NCBI chr15:76,899,941...76,901,297
Ensembl chr15:76,899,910...76,901,305
JBrowse link
G Commd6 COMM domain containing 6 decreases expression ISO cupric chloride results in decreased expression of COMMD6 mRNA CTD PMID:17211630 NCBI chr14:101,633,766...101,640,471
Ensembl chr14:101,632,981...101,640,686
JBrowse link
G Commd7 COMM domain containing 7 decreases expression ISO cupric chloride results in decreased expression of COMMD7 mRNA CTD PMID:17211630 NCBI chr 2:153,616,930...153,632,795
Ensembl chr 2:153,616,933...153,632,781
JBrowse link
G Commd8 COMM domain containing 8 decreases expression ISO cupric chloride results in decreased expression of COMMD8 mRNA CTD PMID:17211630 NCBI chr 5:72,156,576...72,168,189
Ensembl chr 5:72,156,575...72,168,189
JBrowse link
G Cox16 cytochrome c oxidase assembly protein 16 affects expression ISO cupric chloride affects the expression of COX16 mRNA CTD PMID:17211630 NCBI chr12:81,358,852...81,485,137
Ensembl chr12:81,359,026...81,485,127
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression EXP cupric chloride results in decreased expression of COX5B protein CTD PMID:29617964 NCBI chr 1:36,691,487...36,693,388
Ensembl chr 1:36,691,449...36,693,681
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 increases expression EXP cupric chloride results in increased expression of COX6A1 protein CTD PMID:29617964 NCBI chr 5:115,345,652...115,348,958
Ensembl chr 5:115,345,642...115,348,981
JBrowse link
G Cp ceruloplasmin increases expression ISO cupric chloride results in increased expression of CP mRNA CTD PMID:15741220 NCBI chr 3:19,956,933...20,009,750
Ensembl chr 3:19,957,054...20,009,145
JBrowse link
G Cplx2 complexin 2 decreases expression EXP cupric chloride results in decreased expression of CPLX2 protein CTD PMID:29617964 NCBI chr13:54,301,964...54,383,923
Ensembl chr13:54,371,349...54,383,917
JBrowse link
G Cryab crystallin, alpha B increases expression ISO cupric chloride results in increased expression of CRYAB mRNA CTD PMID:17211630 NCBI chr 9:50,745,951...50,756,636
Ensembl chr 9:50,751,325...50,756,636
JBrowse link
G Cstb cystatin B affects binding ISO CSTB protein binds to cupric chloride CTD PMID:16939620 NCBI chr10:78,425,670...78,427,622
Ensembl chr10:78,425,669...78,427,622
JBrowse link
G Ctsb cathepsin B multiple interactions
decreases expression
EXP PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB protein]
cupric chloride results in decreased expression of CTSB mRNA; cupric chloride results in decreased expression of CTSB protein
CTD PMID:32512069 NCBI chr14:63,122,462...63,145,923
Ensembl chr14:63,122,462...63,145,923
JBrowse link
G Ctsd cathepsin D multiple interactions
decreases expression
EXP PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSD mRNA] CTD PMID:32512069 NCBI chr 7:142,375,910...142,387,827
Ensembl chr 7:142,375,911...142,388,038
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases secretion
increases expression
ISO cupric chloride results in increased secretion of CXCL8 protein
cupric chloride results in increased expression of CXCL8 mRNA; cupric chloride results in increased expression of CXCL8 protein
CTD PMID:12865660 PMID:17211630 PMID:29355601 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein CTD PMID:20920558 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538
JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 decreases expression ISO cupric chloride results in decreased expression of CYFIP2 mRNA CTD PMID:17211630 NCBI chr11:46,193,849...46,312,859
Ensembl chr11:46,193,850...46,312,859
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases stability
multiple interactions
EXP cupric chloride results in increased stability of CYP1A1 mRNA; cupric chloride results in increased stability of CYP1A1 protein
[1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]
CTD PMID:19896525 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression EXP cupric chloride results in increased expression of CYP27A1 mRNA CTD PMID:17211630 NCBI chr 1:74,713,148...74,737,897
Ensembl chr 1:74,713,574...74,737,892
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions ISO [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of N'-nitrosonornicotine CTD PMID:32672941 NCBI chr 7:25,897,658...25,926,624
Ensembl chr 7:25,897,620...25,926,624
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 increases expression EXP cupric chloride results in increased expression of CYP2C38 mRNA CTD PMID:17211630 NCBI chr19:39,389,556...39,463,103
Ensembl chr19:39,389,556...39,463,075
JBrowse link
G Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 increases expression EXP cupric chloride results in increased expression of CYP2D26 mRNA CTD PMID:17211630 NCBI chr15:82,790,107...82,794,452
Ensembl chr15:82,790,101...82,794,294
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA]
cupric chloride results in increased expression of DDIT3 mRNA
CTD PMID:17211630 PMID:20920558 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO cupric chloride results in increased expression of DKK1 mRNA CTD PMID:17211630 NCBI chr19:30,545,876...30,549,496
Ensembl chr19:30,545,863...30,549,665
JBrowse link
G Dmd dystrophin, muscular dystrophy increases expression ISO cupric chloride results in increased expression of DMD mRNA CTD PMID:17211630 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO cupric chloride results in increased expression of DNAJB1 mRNA CTD PMID:17211630 NCBI chr 8:83,608,175...83,612,653
Ensembl chr 8:83,608,193...83,612,653
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression EXP cupric chloride results in increased expression of DPYSL2 protein CTD PMID:29617964 NCBI chr14:66,802,864...66,911,041
Ensembl chr14:66,802,864...66,868,688
JBrowse link
G Dpysl5 dihydropyrimidinase-like 5 increases expression EXP cupric chloride results in increased expression of DPYSL5 protein CTD PMID:29617964 NCBI chr 5:30,711,564...30,799,369
Ensembl chr 5:30,711,564...30,799,375
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO cupric chloride results in increased expression of DUSP1 mRNA CTD PMID:17211630 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128
JBrowse link
G Egr1 early growth response 1 affects expression ISO cupric chloride affects the expression of EGR1 mRNA CTD PMID:17211630 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Elac2 elaC ribonuclease Z 2 affects expression ISO cupric chloride affects the expression of ELAC2 mRNA CTD PMID:17211630 NCBI chr11:64,979,030...65,002,080
Ensembl chr11:64,979,038...65,002,069
JBrowse link
G Elovl1 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 increases expression ISO cupric chloride results in increased expression of ELOVL1 mRNA CTD PMID:17211630 NCBI chr 4:118,426,874...118,432,953
Ensembl chr 4:118,428,093...118,432,953
JBrowse link
G Eml4 echinoderm microtubule associated protein like 4 decreases expression ISO cupric chloride results in decreased expression of EML4 mRNA CTD PMID:17211630 NCBI chr17:83,350,930...83,480,361
Ensembl chr17:83,350,931...83,480,361
JBrowse link
G Enam enamelin affects expression ISO cupric chloride affects the expression of ENAM mRNA CTD PMID:17211630 NCBI chr 5:88,487,975...88,506,049
Ensembl chr 5:88,487,975...88,506,049
JBrowse link
G Endog endonuclease G increases expression EXP cupric chloride results in increased expression of ENDOG protein CTD PMID:22239859 NCBI chr 2:30,171,408...30,174,069
Ensembl chr 2:30,171,493...30,174,069
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
increases activity
affects response to substance
decreases expression
ISO cupric chloride inhibits the reaction [Estradiol binds to ESR1 protein]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 mRNA]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 mRNA]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 protein]
cupric chloride results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to cupric chloride
cupric chloride results in decreased expression of ESR1 mRNA; cupric chloride results in decreased expression of ESR1 protein
CTD PMID:12746304 PMID:17716812 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G F2 coagulation factor II increases expression EXP cupric chloride results in increased expression of F2 mRNA CTD PMID:17211630 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G Fam219a family with sequence similarity 219, member A increases expression ISO cupric chloride results in increased expression of FAM219A mRNA CTD PMID:17211630 NCBI chr 4:41,517,691...41,569,607
Ensembl chr 4:41,517,691...41,569,538
JBrowse link
G Fam89b family with sequence similarity 89, member B increases expression ISO cupric chloride results in increased expression of FAM89B mRNA CTD PMID:17211630 NCBI chr19:5,728,087...5,729,666
Ensembl chr19:5,728,087...5,729,653
JBrowse link
G Fetub fetuin beta increases expression EXP cupric chloride results in increased expression of FETUB mRNA CTD PMID:17211630 NCBI chr16:22,918,382...22,939,768
Ensembl chr16:22,918,334...22,939,778
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO [amlexanox binds to FGF1 protein] inhibits the reaction [cupric chloride results in increased oxidation of FGF1 protein] CTD PMID:16300395 NCBI chr18:38,838,672...38,929,470
Ensembl chr18:38,838,673...38,929,472
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 affects expression ISO cupric chloride affects the expression of FGFR1 mRNA CTD PMID:17211630 NCBI chr 8:25,518,759...25,575,718
Ensembl chr 8:25,513,654...25,575,718
JBrowse link
G Fhl3 four and a half LIM domains 3 increases expression ISO cupric chloride results in increased expression of FHL3 mRNA CTD PMID:17211630 NCBI chr 4:124,695,964...124,708,611
Ensembl chr 4:124,700,701...124,708,611
JBrowse link
G Fkbp4 FK506 binding protein 4 increases expression ISO cupric chloride results in increased expression of FKBP4 mRNA CTD PMID:17211630 NCBI chr 6:128,430,103...128,438,656
Ensembl chr 6:128,429,735...128,438,677
JBrowse link
G Fmo5 flavin containing monooxygenase 5 decreases expression ISO cupric chloride results in decreased expression of FMO5 mRNA CTD PMID:17211630 NCBI chr 3:97,609,938...97,655,287
Ensembl chr 3:97,628,804...97,655,282
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO cupric chloride results in increased expression of FOS mRNA CTD PMID:17211630 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Fubp1 far upstream element (FUSE) binding protein 1 increases expression EXP cupric chloride results in increased expression of FUBP1 protein CTD PMID:29617964 NCBI chr 3:152,210,422...152,236,830
Ensembl chr 3:152,210,422...152,236,826
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 affects expression ISO cupric chloride affects the expression of FXYD2 mRNA CTD PMID:17211630 NCBI chr 9:45,399,709...45,410,278
Ensembl chr 9:45,399,669...45,410,278
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked multiple interactions
decreases activity
ISO Carnosine inhibits the reaction [cupric chloride results in decreased activity of G6PD protein] CTD PMID:32745495 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gabre gamma-aminobutyric acid (GABA) A receptor, subunit epsilon increases expression ISO cupric chloride results in increased expression of GABRE mRNA CTD PMID:17211630 NCBI chr  X:72,256,926...72,274,828
Ensembl chr  X:72,255,999...72,274,803
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression ISO cupric chloride results in increased expression of GADD45A mRNA CTD PMID:17211630 NCBI chr 6:67,035,096...67,037,407
Ensembl chr 6:67,035,096...67,037,457
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO cupric chloride results in increased expression of GCLC mRNA CTD PMID:17211630 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO cupric chloride results in increased expression of GCLM mRNA CTD PMID:17211630 PMID:24343273 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Gdi1 guanosine diphosphate (GDP) dissociation inhibitor 1 increases expression EXP cupric chloride results in increased expression of GDI1 protein CTD PMID:29617964 NCBI chr  X:74,305,012...74,311,867
Ensembl chr  X:74,304,998...74,311,862
JBrowse link
G Gla galactosidase, alpha increases expression ISO cupric chloride results in increased expression of GLA mRNA CTD PMID:17211630 NCBI chr  X:134,588,169...134,601,005
Ensembl chr  X:134,588,149...134,601,125
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression ISO cupric chloride results in decreased expression of GLUD1 mRNA CTD PMID:17211630 NCBI chr14:34,310,727...34,345,033
Ensembl chr14:34,310,727...34,345,265
JBrowse link
G Gsr glutathione reductase multiple interactions
decreases activity
ISO Carnosine inhibits the reaction [cupric chloride results in decreased activity of GSR protein] CTD PMID:32745495 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gtpbp2 GTP binding protein 2 affects expression ISO cupric chloride affects the expression of GTPBP2 mRNA CTD PMID:17211630 NCBI chr17:46,159,227...46,169,370
Ensembl chr17:46,161,032...46,169,370
JBrowse link
G Gtpbp6 GTP binding protein 6 (putative) increases expression ISO cupric chloride results in increased expression of GTPBP6 mRNA CTD PMID:17211630 NCBI chr 5:110,103,976...110,108,331
Ensembl chr 5:110,103,975...110,108,197
JBrowse link
G H2-D1 histocompatibility 2, D region locus 1 increases expression EXP cupric chloride results in increased expression of H2-D1 mRNA CTD PMID:17211630 NCBI chr17:35,263,094...35,267,497
Ensembl chr17:35,262,730...35,267,499
JBrowse link
G H2-K1 histocompatibility 2, K1, K region increases expression EXP cupric chloride results in increased expression of H2-K1 mRNA CTD PMID:17211630 NCBI chr17:33,996,012...34,000,619
Ensembl chr17:33,996,017...34,000,347
JBrowse link
G H2-Q10 histocompatibility 2, Q region locus 10 increases expression EXP cupric chloride results in increased expression of H2-Q10 mRNA CTD PMID:17211630 NCBI chr17:35,470,089...35,474,563
Ensembl chr17:35,470,089...35,474,563
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression EXP cupric chloride results in increased expression of HAMP mRNA CTD PMID:17211630 NCBI chr 7:30,942,368...30,944,029
Ensembl chr 7:30,942,368...30,944,032
JBrowse link
G Hexa hexosaminidase A decreases expression
multiple interactions
EXP cupric chloride results in decreased expression of HEXA mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of HEXA mRNA]
CTD PMID:32512069 NCBI chr 9:59,539,540...59,565,109
Ensembl chr 9:59,539,540...59,565,109
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions
increases stability
affects localization
decreases hydroxylation
ISO Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; cupric chloride results in decreased hydroxylation of and results in decreased degradation of HIF1A protein
cupric chloride affects the localization of HIF1A protein
CTD PMID:15741220 PMID:19074761 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hk1 hexokinase 1 decreases activity ISO cupric chloride results in decreased activity of HK1 protein CTD PMID:22349057 NCBI chr10:62,268,855...62,379,920
Ensembl chr10:62,268,855...62,379,908
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO cupric chloride results in increased expression of HMOX1 mRNA; cupric chloride results in increased expression of HMOX1 protein CTD PMID:17211630 PMID:21242307 PMID:24343273 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 increases expression ISO cupric chloride results in increased expression of HSP90AA1 mRNA CTD PMID:17211630 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728
JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA] CTD PMID:20920558 NCBI chr10:86,690,841...86,705,444
Ensembl chr10:86,690,209...86,705,509
JBrowse link
G Hspa1a heat shock protein 1A affects expression ISO cupric chloride affects the expression of HSPA1A mRNA CTD PMID:20945374 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspa1b heat shock protein 1B increases expression ISO cupric chloride results in increased expression of HSPA1B mRNA CTD PMID:17211630 NCBI chr17:34,956,429...34,959,238
Ensembl chr17:34,956,436...34,959,238
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA] CTD PMID:20920558 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Hspa9 heat shock protein 9 decreases expression EXP cupric chloride results in decreased expression of HSPA9 protein CTD PMID:29617964 NCBI chr18:34,937,414...34,954,351
Ensembl chr18:34,937,414...34,954,357
JBrowse link
G Hspb1 heat shock protein 1 increases expression ISO cupric chloride results in increased expression of HSPB1 mRNA CTD PMID:17211630 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Id2 inhibitor of DNA binding 2 affects expression ISO cupric chloride affects the expression of ID2 mRNA CTD PMID:17211630 NCBI chr12:25,093,799...25,096,092
Ensembl chr12:25,093,799...25,097,140
JBrowse link
G Idh3a isocitrate dehydrogenase 3 (NAD+) alpha decreases expression EXP cupric chloride results in decreased expression of IDH3A protein CTD PMID:29617964 NCBI chr 9:54,586,511...54,604,662
Ensembl chr 9:54,586,334...54,604,661
JBrowse link
G Ier2 immediate early response 2 increases expression ISO cupric chloride results in increased expression of IER2 mRNA CTD PMID:17211630 NCBI chr 8:84,661,331...84,662,852
Ensembl chr 8:84,661,331...84,662,854
JBrowse link
G Ier5 immediate early response 5 increases expression ISO cupric chloride results in increased expression of IER5 mRNA CTD PMID:17211630 NCBI chr 1:155,096,367...155,099,636
Ensembl chr 1:155,096,361...155,099,636
JBrowse link
G Ifit1bl1 interferon induced protein with tetratricpeptide repeats 1B like 1 increases expression ISO cupric chloride results in increased expression of IFIT1 mRNA CTD PMID:17211630 NCBI chr19:34,592,888...34,662,981
Ensembl chr19:34,592,891...34,601,956
JBrowse link
G Ifng interferon gamma multiple interactions EXP cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP cupric chloride results in increased expression of IGF1 mRNA CTD PMID:17211630 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Ighmbp2 immunoglobulin mu binding protein 2 increases expression ISO cupric chloride results in increased expression of IGHMBP2 mRNA CTD PMID:17211630 NCBI chr19:3,259,076...3,283,010
Ensembl chr19:3,259,076...3,283,017
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma increases expression ISO cupric chloride results in increased expression of IKBKG mRNA CTD PMID:17211630 NCBI chr  X:74,393,233...74,456,792
Ensembl chr  X:74,393,290...74,453,854
JBrowse link
G Il1a interleukin 1 alpha increases secretion ISO cupric chloride results in increased secretion of IL1A protein CTD PMID:22954531 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il6 interleukin 6 multiple interactions ISO cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:23285694 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Immt inner membrane protein, mitochondrial decreases expression EXP cupric chloride results in decreased expression of IMMT protein CTD PMID:29617964 NCBI chr 6:71,831,091...71,875,266
Ensembl chr 6:71,831,331...71,877,388
JBrowse link
G Irs2 insulin receptor substrate 2 increases expression ISO cupric chloride results in increased expression of IRS2 mRNA CTD PMID:17211630 NCBI chr 8:10,984,681...11,008,929
Ensembl chr 8:10,984,681...11,008,458
JBrowse link
G Jun jun proto-oncogene increases expression
multiple interactions
ISO
EXP
cupric chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
[Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein
CTD PMID:17211630 PMID:21911303 PMID:30768131 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kdm2a lysine (K)-specific demethylase 2A increases expression ISO cupric chloride results in increased expression of KDM2A mRNA CTD PMID:17211630 NCBI chr19:4,316,144...4,398,721
Ensembl chr19:4,314,419...4,398,285
JBrowse link
G Kdm3a lysine (K)-specific demethylase 3A increases expression ISO cupric chloride results in increased expression of KDM3A mRNA CTD PMID:17211630 NCBI chr 6:71,588,970...71,632,990
Ensembl chr 6:71,588,972...71,632,990
JBrowse link
G Kif5a kinesin family member 5A decreases activity
multiple interactions
ISO cupric chloride results in decreased activity of KIF5A protein
Cysteine inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Dithiothreitol inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Egtazic Acid inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]
CTD PMID:24853401 NCBI chr10:127,225,695...127,266,348
Ensembl chr10:127,225,696...127,263,348
JBrowse link
G Klf6 Kruppel-like factor 6 affects expression ISO cupric chloride affects the expression of KLF6 mRNA CTD PMID:17211630 NCBI chr13:5,861,489...5,870,393
Ensembl chr13:5,861,482...5,870,394
JBrowse link
G Kng2 kininogen 2 increases expression EXP cupric chloride results in increased expression of KNG1 mRNA; cupric chloride results in increased expression of KNG2 mRNA CTD PMID:17211630 NCBI chr16:22,985,852...23,029,101
Ensembl chr16:22,985,854...23,029,482
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions
decreases expression
EXP PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 protein]
cupric chloride results in decreased expression of LAMP1 mRNA; cupric chloride results in decreased expression of LAMP1 protein
CTD PMID:32512069 NCBI chr 8:13,159,161...13,175,338
Ensembl chr 8:13,159,161...13,175,338
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 decreases expression
multiple interactions
EXP cupric chloride results in decreased expression of LAMP2 mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP2 mRNA]
CTD PMID:32512069 NCBI chr  X:38,399,647...38,456,460
Ensembl chr  X:38,401,357...38,456,454
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression EXP cupric chloride results in increased expression of LCAT mRNA CTD PMID:17211630 NCBI chr 8:105,939,551...105,943,402
Ensembl chr 8:105,939,551...105,943,382
JBrowse link
G Lox lysyl oxidase increases activity
multiple interactions
EXP
ISO
cupric chloride results in increased activity of LOX protein
Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]
CTD PMID:22367676 PMID:25044713 NCBI chr18:52,516,060...52,529,867
Ensembl chr18:52,516,067...52,529,867
JBrowse link
G Ly6e lymphocyte antigen 6 complex, locus E increases expression EXP cupric chloride results in increased expression of LY6E mRNA CTD PMID:17211630 NCBI chr15:74,955,025...74,959,904
Ensembl chr15:74,955,051...74,959,905
JBrowse link
G Mad2l1bp MAD2L1 binding protein increases expression ISO cupric chloride results in increased expression of MAD2L1BP mRNA CTD PMID:17211630 NCBI chr17:46,147,385...46,153,551
Ensembl chr17:46,147,387...46,153,553
JBrowse link
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) increases expression ISO cupric chloride results in increased expression of MAFG mRNA CTD PMID:17211630 NCBI chr11:120,625,117...120,634,955
Ensembl chr11:120,625,117...120,633,600
JBrowse link
G Magea14 MAGE family member A14 increases expression ISO cupric chloride results in increased expression of MAGEA2 mRNA CTD PMID:17211630 NCBI chr  X:51,968,693...51,973,502
Ensembl chr  X:51,968,695...51,972,772
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO
EXP
cupric chloride results in increased expression of MAP1LC3B mRNA
cupric chloride results in increased expression of MAP1LC3B protein modified form
Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]; cupric chloride inhibits the reaction [3-methyladenine results in decreased expression of MAP1LC3B protein modified form]; PP242 promotes the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]
CTD PMID:17211630 PMID:32512069 NCBI chr 8:121,590,438...121,598,760
Ensembl chr 8:121,590,361...121,598,760
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein CTD PMID:20920558 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein CTD PMID:20920558 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO
EXP
[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]
CTD PMID:11239917 PMID:20920558 PMID:30768131 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] CTD PMID:19789329 NCBI chr 6:88,883,474...88,898,780
Ensembl chr 6:88,883,474...88,898,780
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] CTD PMID:19789329 NCBI chr 8:75,109,468...75,128,439
Ensembl chr 8:75,109,569...75,128,439
JBrowse link
G Mdh2 malate dehydrogenase 2, NAD (mitochondrial) increases expression EXP cupric chloride results in increased expression of MDH2 protein CTD PMID:29617964 NCBI chr 5:135,778,649...135,790,386
Ensembl chr 5:135,778,480...135,790,398
JBrowse link
G Med15 mediator complex subunit 15 increases expression ISO cupric chloride results in increased expression of MED15 mRNA CTD PMID:17211630 NCBI chr16:17,651,208...17,722,947
Ensembl chr16:17,651,208...17,732,891
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein CTD PMID:24193513 NCBI chr 7:136,894,463...137,128,193
Ensembl chr 7:136,894,614...137,130,266
JBrowse link
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 increases expression ISO cupric chloride results in increased expression of MLLT11 mRNA CTD PMID:17211630 NCBI chr 3:95,218,544...95,229,632
Ensembl chr 3:95,219,135...95,232,171
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases secretion ISO cupric chloride results in increased secretion of MMP2 protein CTD PMID:11045606 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mrpl4 mitochondrial ribosomal protein L4 increases expression ISO cupric chloride results in increased expression of MRPL4 mRNA CTD PMID:17211630 NCBI chr 9:21,001,252...21,008,839
Ensembl chr 9:21,002,738...21,008,839
JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO cupric chloride results in increased expression of MSRB1 mRNA CTD PMID:17211630 NCBI chr17:24,736,593...24,742,778
Ensembl chr17:24,736,642...24,742,778
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
decreases expression
ISO cupric chloride results in increased expression of MT1A mRNA
cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1X mRNA]
cupric chloride deficiency results in decreased expression of MT1X mRNA
cupric chloride results in increased expression of MT1X mRNA
CTD PMID:17211630 PMID:19789329 PMID:23174565 PMID:24343273 NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Mt2 metallothionein 2 multiple interactions
increases expression
affects expression
ISO cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]
cupric chloride results in increased expression of MT2A mRNA
cupric chloride affects the expression of MT2A mRNA
CTD PMID:17211630 PMID:17409708 PMID:19789329 PMID:20945374 PMID:23174565 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation EXP cupric chloride results in increased phosphorylation of MTOR protein CTD PMID:32512069 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO cupric chloride results in increased expression of NCF2 mRNA CTD PMID:17211630 NCBI chr 1:152,800,153...152,836,990
Ensembl chr 1:152,800,194...152,836,991
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression EXP cupric chloride results in decreased expression of NDUFS1 protein CTD PMID:29617964 NCBI chr 1:63,143,592...63,176,822
Ensembl chr 1:63,143,596...63,176,833
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 decreases expression EXP cupric chloride results in decreased expression of NDUFS4 protein CTD PMID:29617964 NCBI chr13:114,287,795...114,388,094
Ensembl chr13:114,287,795...114,388,258
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 decreases expression EXP cupric chloride results in decreased expression of NDUFV1 protein CTD PMID:29617964 NCBI chr19:4,007,499...4,012,755
Ensembl chr19:4,007,384...4,012,806
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase core subunit V3 decreases expression EXP cupric chloride results in decreased expression of NDUFV3 protein CTD PMID:29617964 NCBI chr17:31,520,115...31,531,326
Ensembl chr17:31,520,115...31,531,331
JBrowse link
G Nefl neurofilament, light polypeptide decreases expression EXP cupric chloride results in decreased expression of NEFL protein CTD PMID:29617964 NCBI chr14:68,083,863...68,089,095
Ensembl chr14:68,083,863...68,089,095
JBrowse link
G Nfix nuclear factor I/X decreases expression ISO cupric chloride results in decreased expression of NFIX mRNA CTD PMID:17211630 NCBI chr 8:84,704,712...84,801,238
Ensembl chr 8:84,699,876...84,800,344
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha decreases expression ISO cupric chloride results in decreased expression of NFKBIA protein CTD PMID:24530511 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression EXP cupric chloride results in increased expression of NME1 protein CTD PMID:29617964 NCBI chr11:93,958,925...93,968,272
Ensembl chr11:93,956,979...93,968,521
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression
EXP
ISO
cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]
cupric chloride results in increased expression of NOS2 protein
CTD PMID:8975779 PMID:23313662 PMID:24170445 PMID:24530511 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nup107 nucleoporin 107 increases expression ISO cupric chloride results in increased expression of NUP107 mRNA CTD PMID:17211630 NCBI chr10:117,750,621...117,792,736
Ensembl chr10:117,750,621...117,792,705
JBrowse link
G P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 multiple interactions ISO cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr 5:110,339,812...110,343,320
Ensembl chr 5:110,339,812...110,343,212
JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 (non-enzymatic) affects expression ISO cupric chloride affects the expression of P3H4 mRNA CTD PMID:17211630 NCBI chr11:100,408,467...100,414,716
Ensembl chr11:100,408,456...100,414,836
JBrowse link
G Palld palladin, cytoskeletal associated protein increases expression ISO cupric chloride results in increased expression of PALLD mRNA CTD PMID:17211630 NCBI chr 8:61,511,431...61,902,707
Ensembl chr 8:61,511,433...61,902,690
JBrowse link
G Paqr8 progestin and adipoQ receptor family member VIII decreases expression ISO cupric chloride results in decreased expression of PAQR8 mRNA CTD PMID:17211630 NCBI chr 1:20,890,548...20,939,650
Ensembl chr 1:20,890,606...20,939,650
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases expression
ISO
EXP
[Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein
cupric chloride results in increased expression of PARP1 protein
CTD PMID:19789329 PMID:21035945 PMID:23313662 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pcm1 pericentriolar material 1 decreases expression ISO cupric chloride results in decreased expression of PCM1 mRNA CTD PMID:17211630 NCBI chr 8:41,239,484...41,334,088
Ensembl chr 8:41,239,752...41,332,344
JBrowse link
G Pdia3 protein disulfide isomerase associated 3 decreases expression EXP cupric chloride results in decreased expression of PDIA3 protein CTD PMID:29617964 NCBI chr 2:121,413,902...121,438,687
Ensembl chr 2:121,413,775...121,438,687
JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO cupric chloride results in decreased expression of PDZK1 mRNA CTD PMID:17211630 NCBI chr 3:96,829,456...96,870,926
Ensembl chr 3:96,829,284...96,870,926
JBrowse link
G Peg10 paternally expressed 10 decreases expression ISO cupric chloride results in decreased expression of PEG10 mRNA CTD PMID:17211630 NCBI chr 6:4,747,306...4,760,517
Ensembl chr 6:4,747,306...4,760,517
JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression EXP cupric chloride results in increased expression of PGAM1 protein CTD PMID:29617964 NCBI chr19:41,911,871...41,918,665
Ensembl chr19:41,911,923...41,918,660
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
ISO cupric chloride promotes the reaction [Estradiol results in increased expression of PGR mRNA]; cupric chloride promotes the reaction [Estradiol results in increased expression of PGR protein]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR mRNA]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR protein]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR protein]
cupric chloride results in increased expression of PGR mRNA; cupric chloride results in increased expression of PGR protein
CTD PMID:12746304 NCBI chr 9:8,898,900...8,968,611
Ensembl chr 9:8,899,833...8,968,611
JBrowse link
G Phyhip phytanoyl-CoA hydroxylase interacting protein decreases expression ISO cupric chloride results in decreased expression of PHYHIP mRNA CTD PMID:17211630 NCBI chr14:70,457,517...70,468,826
Ensembl chr14:70,457,476...70,468,832
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 decreases expression ISO cupric chloride results in decreased expression of PITPNC1 mRNA CTD PMID:17211630 NCBI chr11:107,207,892...107,470,720
Ensembl chr11:107,207,892...107,470,699
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
ISO cupric chloride results in increased expression of PMAIP1 mRNA
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of PMAIP1 protein
CTD PMID:20713136 PMID:21035945 NCBI chr18:66,458,604...66,465,558
Ensembl chr18:66,458,533...66,465,565
JBrowse link
G Pomp proteasome maturation protein increases expression ISO cupric chloride results in increased expression of POMP mRNA CTD PMID:17211630 NCBI chr 5:147,860,628...147,875,784
Ensembl chr 5:147,860,461...147,876,456
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO cupric chloride results in increased expression of PRDX1 mRNA CTD PMID:17211630 NCBI chr 4:116,685,599...116,700,000
Ensembl chr 4:116,685,544...116,700,822
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression EXP cupric chloride results in decreased expression of PRDX3 protein CTD PMID:29617964 NCBI chr19:60,864,066...60,874,538
Ensembl chr19:60,864,051...60,874,556
JBrowse link
G Prnp prion protein multiple interactions
increases expression
EXP
ISO
[NADP co-treated with cupric chloride] promotes the reaction [PRNP protein binds to PRNP protein]
bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein]
cupric chloride results in increased expression of PRNP mRNA; cupric chloride results in increased expression of PRNP protein
CTD PMID:16148034 PMID:16990274 NCBI chr 2:131,909,928...131,938,436
Ensembl chr 2:131,909,928...131,938,429
JBrowse link
G Proc protein C multiple interactions ISO ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; aspartyl-alanyl-histidyl-lysine inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; cupric chloride binds to and results in decreased activity of PROC protein CTD PMID:11820775 NCBI chr18:32,123,126...32,139,570
Ensembl chr18:32,123,126...32,139,570
JBrowse link
G Psmb2 proteasome (prosome, macropain) subunit, beta type 2 increases expression ISO cupric chloride results in increased expression of PSMB2 mRNA CTD PMID:17211630 NCBI chr 4:126,677,637...126,709,715
Ensembl chr 4:126,677,630...126,709,714
JBrowse link
G Psmb3 proteasome (prosome, macropain) subunit, beta type 3 increases expression ISO cupric chloride results in increased expression of PSMB3 mRNA CTD PMID:17211630 NCBI chr11:97,703,434...97,713,500
Ensembl chr11:97,703,399...97,713,500
JBrowse link
G Psmb7 proteasome (prosome, macropain) subunit, beta type 7 increases expression ISO cupric chloride results in increased expression of PSMB7 mRNA CTD PMID:17211630 NCBI chr 2:38,588,046...38,643,952
Ensembl chr 2:38,588,036...38,644,087
JBrowse link
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 increases expression ISO cupric chloride results in increased expression of PSMC1 mRNA CTD PMID:17211630 NCBI chr12:100,110,202...100,123,364
Ensembl chr12:100,110,154...100,123,405
JBrowse link
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 increases expression ISO cupric chloride results in increased expression of PSMC4 mRNA CTD PMID:17211630 NCBI chr 7:28,041,702...28,050,092
Ensembl chr 7:28,041,707...28,050,101
JBrowse link
G Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 increases expression ISO cupric chloride results in increased expression of PSMD1 mRNA CTD PMID:17211630 NCBI chr 1:86,064,619...86,139,295
Ensembl chr 1:86,064,387...86,139,151
JBrowse link
G Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 increases expression ISO cupric chloride results in increased expression of PSMD11 mRNA CTD PMID:17211630 NCBI chr11:80,428,615...80,473,248
Ensembl chr11:80,428,615...80,473,248
JBrowse link
G Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 increases expression ISO cupric chloride results in increased expression of PSMD13 mRNA CTD PMID:17211630 NCBI chr 7:140,882,394...140,898,642
Ensembl chr 7:140,881,968...140,898,643
JBrowse link
G Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 increases expression ISO cupric chloride results in increased expression of PSMD14 mRNA CTD PMID:17211630 NCBI chr 2:61,711,694...61,800,376
Ensembl chr 2:61,711,694...61,800,376
JBrowse link
G Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 increases expression ISO cupric chloride results in increased expression of PSMD2 mRNA CTD PMID:17211630 NCBI chr16:20,651,122...20,663,414
Ensembl chr16:20,651,652...20,663,414
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP cupric chloride results in increased expression of PTGS2 protein CTD PMID:23313662 PMID:24170445 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O decreases expression ISO cupric chloride results in decreased expression of PTPRO mRNA CTD PMID:17211630 NCBI chr 6:137,252,299...137,464,634
Ensembl chr 6:137,252,319...137,463,233
JBrowse link
G Pura purine rich element binding protein A decreases expression EXP cupric chloride results in decreased expression of PURA protein CTD PMID:29617964 NCBI chr18:36,280,560...36,292,535
Ensembl chr18:36,281,097...36,292,535
JBrowse link
G Qk quaking, KH domain containing RNA binding increases expression ISO cupric chloride results in increased expression of QKI mRNA CTD PMID:17211630 NCBI chr17:10,206,471...10,319,361
Ensembl chr17:10,202,601...10,319,854
JBrowse link
G Ralgapa1 Ral GTPase activating protein, alpha subunit 1 affects expression ISO cupric chloride affects the expression of RALGAPA1 mRNA CTD PMID:17211630 NCBI chr12:55,602,888...55,821,574
Ensembl chr12:55,602,896...55,821,167
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO cupric chloride results in increased phosphorylation of and affects the localization of RELA protein CTD PMID:24530511 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rhob ras homolog family member B decreases expression ISO cupric chloride results in decreased expression of ARHB mRNA CTD PMID:17211630 NCBI chr12:8,497,661...8,500,009
Ensembl chr12:8,497,661...8,500,009
JBrowse link
G Rnf181 ring finger protein 181 affects expression ISO cupric chloride affects the expression of RNF181 mRNA CTD PMID:17211630 NCBI chr 6:72,359,712...72,366,994
Ensembl chr 6:72,359,714...72,366,956
JBrowse link
G Rpl32 ribosomal protein L32 affects expression ISO cupric chloride affects the expression of RPL32 mRNA CTD PMID:17211630 NCBI chr 6:115,805,514...115,808,743
Ensembl chr 6:115,805,505...115,808,747
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 increases phosphorylation EXP cupric chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:32512069 NCBI chr11:86,498,869...86,544,885
Ensembl chr11:86,498,871...86,544,805
JBrowse link
G Rrad Ras-related associated with diabetes increases expression ISO cupric chloride results in increased expression of RRAD mRNA CTD PMID:17211630 NCBI chr 8:104,628,070...104,631,350
Ensembl chr 8:104,628,070...104,631,327
JBrowse link
G Rybp RING1 and YY1 binding protein affects expression ISO cupric chloride affects the expression of RYBP mRNA CTD PMID:17211630 NCBI chr 6:100,228,565...100,287,358
Ensembl chr 6:100,228,565...100,287,485
JBrowse link
G Sbds SBDS ribosome maturation factor increases expression ISO cupric chloride results in increased expression of SBDS mRNA CTD PMID:17211630 NCBI chr 5:130,245,732...130,255,530
Ensembl chr 5:130,245,731...130,255,530
JBrowse link
G Sco2 SCO2 cytochrome c oxidase assembly protein multiple interactions ISO cupric chloride promotes the reaction [Bezafibrate results in increased activity of SCO2 protein mutant form] CTD PMID:22515166 NCBI chr15:89,371,630...89,373,891
Ensembl chr15:89,371,637...89,373,846
JBrowse link
G Sdf2 stromal cell derived factor 2 increases expression ISO cupric chloride results in increased expression of SDF2 mRNA CTD PMID:17211630 NCBI chr11:78,245,746...78,255,496
Ensembl chr11:78,245,746...78,255,496
JBrowse link
G Selenok selenoprotein K increases expression ISO cupric chloride results in increased expression of SELENOK mRNA CTD PMID:17211630 NCBI chr14:29,968,380...29,975,074
Ensembl chr14:29,968,308...29,975,662
JBrowse link
G Selenop selenoprotein P decreases expression ISO cupric chloride results in decreased expression of SELENOP mRNA CTD PMID:17211630 NCBI chr15:3,270,767...3,280,510
Ensembl chr15:3,268,547...3,280,508
JBrowse link
G Septin4 septin 4 decreases expression EXP cupric chloride results in decreased expression of SEPTIN4 protein CTD PMID:29617964 NCBI chr11:87,566,689...87,590,543
Ensembl chr11:87,566,653...87,590,539
JBrowse link
G Septin8 septin 8 decreases expression EXP cupric chloride results in decreased expression of SEPTIN8 protein CTD PMID:29617964 NCBI chr11:53,519,397...53,549,605
Ensembl chr11:53,519,257...53,549,565
JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 increases expression EXP cupric chloride results in increased expression of SERPINF1 mRNA CTD PMID:17211630 NCBI chr11:75,410,029...75,422,623
Ensembl chr11:75,409,769...75,422,701
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein CTD PMID:25007851 NCBI chr 7:143,978,077...144,426,043
Ensembl chr 7:144,001,928...144,424,494
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 NCBI chr15:89,493,013...89,560,261
Ensembl chr15:89,499,623...89,560,261
JBrowse link
G Sirt7 sirtuin 7 increases expression ISO cupric chloride results in increased expression of SIRT7 mRNA CTD PMID:17211630 NCBI chr11:120,618,371...120,625,014
Ensembl chr11:120,618,372...120,625,240
JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 multiple interactions ISO cupric chloride inhibits the reaction [SLC11A2 protein results in increased uptake of Iron] CTD PMID:12220667 NCBI chr15:100,387,898...100,424,209
Ensembl chr15:100,387,898...100,425,072
JBrowse link
G Slc13a3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 decreases expression ISO cupric chloride results in decreased expression of SLC13A3 mRNA CTD PMID:17211630 NCBI chr 2:165,405,295...165,473,197
Ensembl chr 2:165,405,028...165,473,230
JBrowse link
G Slc22a18 solute carrier family 22 (organic cation transporter), member 18 increases expression EXP cupric chloride results in increased expression of SLC22A18 mRNA CTD PMID:17211630 NCBI chr 7:143,473,726...143,499,334
Ensembl chr 7:143,473,736...143,499,334
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 increases expression ISO cupric chloride results in increased expression of SLC2A1 mRNA CTD PMID:15741220 NCBI chr 4:119,108,745...119,137,330
Ensembl chr 4:119,108,711...119,137,983
JBrowse link
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 increases expression ISO cupric chloride results in increased expression of SLC30A1 mRNA CTD PMID:24343273 NCBI chr 1:191,906,697...191,913,248
Ensembl chr 1:191,906,767...191,913,247
JBrowse link
G Slc31a1 solute carrier family 31, member 1 decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of SLC31A1 protein
SLC31A1 protein results in increased susceptibility to [cupric chloride results in increased abundance of Copper]
CTD PMID:24316150 PMID:24800945 PMID:32278528 NCBI chr 4:62,360,583...62,391,769
Ensembl chr 4:62,360,727...62,391,769
JBrowse link
G Snca synuclein, alpha affects folding ISO cupric chloride affects the folding of SNCA protein CTD PMID:11553618 NCBI chr 6:60,731,573...60,829,855
Ensembl chr 6:60,731,575...60,829,855
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
decreases activity
decreases expression
increases response to substance
ISO
EXP
Carnosine inhibits the reaction [cupric chloride results in decreased activity of SOD1 protein]; cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form results in increased susceptibility to cupric chloride]; SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]
cupric chloride results in decreased expression of SOD1 protein
CTD PMID:15812313 PMID:24691167 PMID:29617964 PMID:32745495 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO cupric chloride results in decreased expression of SORBS1 mRNA CTD PMID:17211630 NCBI chr19:40,292,040...40,513,955
Ensembl chr19:40,294,753...40,513,779
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO cupric chloride results in increased expression of SPSB1 mRNA CTD PMID:17211630 NCBI chr 4:149,896,283...149,955,006
Ensembl chr 4:149,896,283...149,955,043
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
cupric chloride results in increased expression of SQSTM1 mRNA
Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]; PP242 inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]
CTD PMID:17211630 PMID:23313662 PMID:32512069 NCBI chr11:50,200,152...50,210,820
Ensembl chr11:50,199,366...50,210,827
JBrowse link
G St6gal1 beta galactoside alpha 2,6 sialyltransferase 1 decreases expression ISO cupric chloride results in decreased expression of ST6GAL1 mRNA CTD PMID:17211630 NCBI chr16:23,224,729...23,360,350
Ensembl chr16:23,224,740...23,360,350
JBrowse link
G Stau1 staufen double-stranded RNA binding protein 1 decreases expression ISO cupric chloride results in decreased expression of STAU mRNA CTD PMID:17211630 NCBI chr 2:166,947,549...166,996,315
Ensembl chr 2:166,947,549...166,996,299
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP cupric chloride results in decreased expression of STMN1 protein CTD PMID:29617964 NCBI chr 4:134,468,320...134,473,843
Ensembl chr 4:134,468,320...134,473,843
JBrowse link
G Syn2 synapsin II decreases expression EXP cupric chloride results in decreased expression of SYN2 protein CTD PMID:29617964 NCBI chr 6:115,134,902...115,282,626
Ensembl chr 6:115,134,902...115,282,006
JBrowse link
G Taf7l TATA-box binding protein associated factor 7 like increases expression ISO cupric chloride results in increased expression of TAF7L mRNA CTD PMID:17211630 NCBI chr  X:134,460,116...134,476,505
Ensembl chr  X:134,460,118...134,476,490
JBrowse link
G Taldo1 transaldolase 1 increases expression ISO cupric chloride results in increased expression of TALDO1 mRNA CTD PMID:17211630 NCBI chr 7:141,392,160...141,402,976
Ensembl chr 7:141,392,199...141,402,968
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO cupric chloride inhibits the reaction [Paraquat affects the localization of TARDBP protein] CTD PMID:22879928 NCBI chr 4:148,612,382...148,627,084
Ensembl chr 4:148,612,382...148,627,019
JBrowse link
G Tfdp2 transcription factor Dp 2 affects expression ISO cupric chloride affects the expression of TFDP2 mRNA CTD PMID:17211630 NCBI chr 9:96,196,246...96,323,646
Ensembl chr 9:96,196,275...96,323,646
JBrowse link
G Tfeb transcription factor EB decreases expression
multiple interactions
EXP cupric chloride results in decreased expression of TFEB mRNA; cupric chloride results in decreased expression of TFEB protein
PP242 inhibits the reaction [cupric chloride results in decreased expression of TFEB protein]
CTD PMID:32512069 NCBI chr17:47,737,037...47,792,416
Ensembl chr17:47,737,030...47,792,419
JBrowse link
G Tkt transketolase increases expression ISO cupric chloride results in increased expression of TKT mRNA CTD PMID:17211630 NCBI chr14:30,549,131...30,574,724
Ensembl chr14:30,548,359...30,574,720
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 decreases expression ISO cupric chloride results in decreased expression of TMED2 mRNA CTD PMID:17211630 NCBI chr 5:124,540,791...124,550,503
Ensembl chr 5:124,540,695...124,550,506
JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
increases expression
ISO
EXP
cupric chloride results in increased secretion of TNF protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; SC 514 inhibits the reaction [cupric chloride results in increased secretion of TNF protein]
cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
cupric chloride results in increased expression of TNF protein
CTD PMID:22954531 PMID:23285694 PMID:23313662 PMID:24170445 PMID:24530511 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tpm1 tropomyosin 1, alpha increases expression EXP cupric chloride results in increased expression of TPM1 protein CTD PMID:29617964 NCBI chr 9:67,022,590...67,049,672
Ensembl chr 9:67,022,590...67,049,406
JBrowse link
G Tppp tubulin polymerization promoting protein increases expression EXP cupric chloride results in increased expression of TPPP protein CTD PMID:29617964 NCBI chr13:74,009,419...74,035,753
Ensembl chr13:74,009,407...74,035,753
JBrowse link
G Traf5 TNF receptor-associated factor 5 increases expression ISO cupric chloride results in increased expression of TRAF5 mRNA CTD PMID:17211630 NCBI chr 1:191,997,203...192,092,599
Ensembl chr 1:191,997,205...192,092,559
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO cupric chloride results in increased expression of TRIB3 mRNA CTD PMID:17211630 NCBI chr 2:152,337,425...152,344,060
Ensembl chr 2:152,337,422...152,344,032
JBrowse link
G Trp53 transformation related protein 53 affects expression
multiple interactions
decreases expression
increases expression
EXP
ISO
cupric chloride affects the expression of TRP53 mRNA
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]
cupric chloride results in decreased expression of TRP53 protein
cupric chloride results in increased expression of TRP53 protein
CTD PMID:23313662 PMID:24170445 PMID:29803612 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Trp73 transformation related protein 73 affects expression
increases expression
EXP cupric chloride affects the expression of TRP73 protein
cupric chloride results in increased expression of TRP73 protein
CTD PMID:23313662 PMID:24170445 NCBI chr 4:154,056,249...154,139,875
Ensembl chr 4:154,056,253...154,140,208
Ensembl chr 4:154,056,253...154,140,208
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [cupric chloride results in increased abundance of Copper] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:140,539,528...140,600,522
Ensembl chr  X:140,539,528...140,600,659
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO cupric chloride results in increased expression of TXN mRNA CTD PMID:17211630 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txnl1 thioredoxin-like 1 increases expression ISO cupric chloride results in increased expression of TXNL1 mRNA CTD PMID:17211630 NCBI chr18:63,662,801...63,692,359
Ensembl chr18:63,661,094...63,708,801
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO cupric chloride results in increased expression of TXNRD1 mRNA CTD PMID:17211630 NCBI chr10:82,833,951...82,897,724
Ensembl chr10:82,833,951...82,897,712
JBrowse link
G Tyr tyrosinase multiple interactions ISO cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]] CTD PMID:11092760 NCBI chr 7:87,424,771...87,493,512
Ensembl chr 7:87,424,771...87,493,512
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO cupric chloride promotes the reaction [Dimethyldithiocarbamate results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; cupric chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:20,658,302...20,683,179
Ensembl chr  X:20,658,326...20,683,179
JBrowse link
G Ubc ubiquitin C increases expression ISO cupric chloride results in increased expression of UBC mRNA CTD PMID:17211630 NCBI chr 5:125,385,965...125,390,017
Ensembl chr 5:125,385,965...125,390,202
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 increases expression ISO cupric chloride results in increased expression of UBR5 mRNA CTD PMID:17211630 NCBI chr15:37,967,328...38,078,862
Ensembl chr15:37,967,328...38,078,854
JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 increases expression EXP cupric chloride results in increased expression of UCHL1 protein CTD PMID:29617964 NCBI chr 5:66,676,121...66,687,234
Ensembl chr 5:66,676,091...66,687,234
JBrowse link
G Ufd1 ubiquitin recognition factor in ER-associated degradation 1 increases expression ISO cupric chloride results in increased expression of UFD1 mRNA CTD PMID:17211630 NCBI chr16:18,811,736...18,835,261
Ensembl chr16:18,811,779...18,835,261
JBrowse link
G Unkl unkempt family like zinc finger increases expression ISO cupric chloride results in increased expression of UNKL mRNA CTD PMID:17211630 NCBI chr17:25,188,361...25,234,443
Ensembl chr17:25,188,397...25,234,443
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression EXP cupric chloride results in increased expression of UQCRC1 protein CTD PMID:29617964 NCBI chr 9:108,936,648...108,949,641
Ensembl chr 9:108,936,633...108,949,623
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein decreases expression EXP cupric chloride results in decreased expression of UQCRH protein CTD PMID:29617964 NCBI chr 4:116,066,965...116,075,070
Ensembl chr 4:116,066,965...116,075,071
JBrowse link
G Utp11 UTP11 small subunit processome component increases expression ISO cupric chloride results in increased expression of UTP11 mRNA CTD PMID:17211630 NCBI chr 4:124,678,232...124,693,610
Ensembl chr 4:124,678,160...124,693,600
JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression EXP cupric chloride results in increased expression of VDAC1 protein CTD PMID:29617964 NCBI chr11:52,360,851...52,389,397
Ensembl chr11:52,360,860...52,389,397
JBrowse link
G Vdac2 voltage-dependent anion channel 2 increases expression EXP cupric chloride results in increased expression of VDAC2 protein CTD PMID:29617964 NCBI chr14:21,831,561...21,845,879
Ensembl chr14:21,825,238...21,845,879
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO cupric chloride results in increased expression of VEGFA mRNA CTD PMID:15741220 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vps13b vacuolar protein sorting 13B affects expression ISO cupric chloride affects the expression of VPS13B mRNA CTD PMID:17211630 NCBI chr15:35,371,118...35,931,229
Ensembl chr15:35,371,160...35,931,229
JBrowse link
G Wdr74 WD repeat domain 74 affects expression ISO cupric chloride affects the expression of WDR74 mRNA CTD PMID:17211630 NCBI chr19:8,735,795...8,740,624
Ensembl chr19:8,735,827...8,740,624
JBrowse link
G Zfp12 zinc finger protein 12 increases expression ISO cupric chloride results in increased expression of ZNF12 mRNA CTD PMID:17211630 NCBI chr 5:143,235,138...143,248,834
Ensembl chr 5:143,235,163...143,248,834
JBrowse link
G Znrd2 zinc ribbon domain containing 2 increases expression ISO cupric chloride results in increased expression of ZNRD2 mRNA CTD PMID:17211630 NCBI chr19:5,730,306...5,731,732
Ensembl chr19:5,728,088...5,731,713
Ensembl chr19:5,728,088...5,731,713
JBrowse link
G Zswim6 zinc finger SWIM-type containing 6 affects expression ISO cupric chloride affects the expression of ZSWIM6 mRNA CTD PMID:17211630 NCBI chr13:107,724,617...107,890,064
Ensembl chr13:107,724,617...107,890,064
JBrowse link
trifluoperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A increases activity ISO Trifluoperazine results in increased activity of ABCB1 protein CTD PMID:2900677 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Ache acetylcholinesterase multiple interactions
increases activity
decreases expression
ISO
EXP
energostim inhibits the reaction [Trifluoperazine results in decreased expression of ACHE protein]
Trifluoperazine results in increased activity of ACHE protein
CTD PMID:15232633 PMID:29614332 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:19233221 PMID:21544200 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA CTD PMID:28366621 NCBI chr 1:5,082,978...5,163,213
Ensembl chr 1:5,070,018...5,162,529
JBrowse link
G Bax BCL2-associated X protein increases expression ISO Trifluoperazine results in increased expression of BAX protein CTD PMID:21475906 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO Trifluoperazine results in decreased expression of BCL2 protein CTD PMID:21475906 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of CAMK2A protein] CTD PMID:19233221 NCBI chr18:60,925,307...60,988,152
Ensembl chr18:60,925,618...60,988,152
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein] CTD PMID:21544200 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cd44 CD44 antigen multiple interactions EXP Trifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein] CTD PMID:9929743 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:21544200 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674
JBrowse link
G Fmo2 flavin containing monooxygenase 2 increases oxidation ISO FMO2 protein results in increased oxidation of Trifluoperazine CTD PMID:26062974 NCBI chr 1:162,874,317...162,898,758
Ensembl chr 1:162,874,317...162,898,726
JBrowse link
G Gabbr1 gamma-aminobutyric acid (GABA) B receptor, 1 multiple interactions ISO Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:15627515 NCBI chr17:37,045,966...37,074,305
Ensembl chr17:37,045,966...37,075,067
JBrowse link
G Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 multiple interactions ISO Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:15627515 NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit decreases expression ISO Trifluoperazine results in decreased expression of HIF1A protein CTD PMID:18822394 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Il12b interleukin 12b multiple interactions EXP Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IL12B protein] CTD PMID:16249388 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 multiple interactions ISO Trifluoperazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:21158687 NCBI chr 5:24,319,589...24,351,684
Ensembl chr 5:24,319,589...24,351,604
JBrowse link
G Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 decreases activity ISO Trifluoperazine results in decreased activity of KCNN2 protein CTD PMID:10915830 NCBI chr18:45,268,750...45,685,887
Ensembl chr18:45,268,860...45,686,024
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA CTD PMID:28366621 NCBI chr 8:13,159,161...13,175,338
Ensembl chr 8:13,159,161...13,175,338
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK1 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Trifluoperazine inhibits the reaction [Dinoprost results in increased activity of MAPK1 protein] CTD PMID:11914123 PMID:21544200 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein] CTD PMID:21544200 NCBI chr17:28,691,342...28,748,405
Ensembl chr17:28,691,329...28,748,406
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK3 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Trifluoperazine inhibits the reaction [Dinoprost results in increased activity of MAPK3 protein] CTD PMID:11914123 PMID:21544200 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:21544200 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Trifluoperazine results in increased expression of MT1A mRNA CTD PMID:8128501 NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MTOR protein] CTD PMID:21544200 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MYL9 protein]; Trifluoperazine inhibits the reaction [Ionomycin results in increased phosphorylation of MYL9 protein] CTD PMID:19233221 NCBI chr 2:156,775,408...156,781,657
Ensembl chr 2:156,775,420...156,781,658
JBrowse link
G Nefl neurofilament, light polypeptide multiple interactions ISO Trifluoperazine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:31969611 NCBI chr14:68,083,863...68,089,095
Ensembl chr14:68,083,863...68,089,095
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases activity EXP Trifluoperazine results in decreased activity of NR3C1 protein CTD PMID:7887964 NCBI chr18:39,410,545...39,519,421
Ensembl chr18:39,410,545...39,519,421
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] CTD PMID:21544200 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pink1 PTEN induced putative kinase 1 multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 4:138,313,409...138,326,296
Ensembl chr 4:138,313,409...138,326,307
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions
affects localization
ISO PRKN protein affects the reaction [Trifluoperazine affects the localization of PRKN protein] CTD PMID:28366621 NCBI chr17:10,840,359...12,063,370
Ensembl chr17:10,840,384...12,063,361
JBrowse link
G Prl prolactin increases expression ISO Trifluoperazine results in increased expression of PRL protein CTD PMID:2136057 NCBI chr13:27,057,570...27,065,204
Ensembl chr13:27,057,570...27,065,205
JBrowse link
G Rel reticuloendotheliosis oncogene multiple interactions EXP Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased localization of REL protein] CTD PMID:16249388 NCBI chr11:23,736,847...23,770,969
Ensembl chr11:23,736,847...23,770,970
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 NCBI chr11:86,498,869...86,544,885
Ensembl chr11:86,498,871...86,544,805
JBrowse link
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 multiple interactions ISO Trifluoperazine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 5:31,036,036...31,048,924
Ensembl chr 5:31,036,036...31,048,924
JBrowse link
G Tfeb transcription factor EB multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr17:47,737,037...47,792,416
Ensembl chr17:47,737,030...47,792,419
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 decreases activity EXP Trifluoperazine results in decreased activity of TNFSF11 CTD PMID:21869564 NCBI chr14:78,277,446...78,308,043
Ensembl chr14:78,277,445...78,308,043
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 multiple interactions
increases activity
increases glucuronidation
ISO Finasteride inhibits the reaction [UGT1A4 protein results in increased glucuronidation of Trifluoperazine]; hecogenin inhibits the reaction [UGT1A4 protein results in increased glucuronidation of Trifluoperazine]; licochalcone A inhibits the reaction [Trifluoperazine results in increased activity of UGT1A4 protein]; Trifluoperazine inhibits the reaction [UGT1A4 protein results in increased glucuronidation of afloqualone] CTD PMID:15135306 PMID:15475412 PMID:25393417 PMID:25448279 PMID:26875642 More... NCBI chr 1:88,166,012...88,220,002
Ensembl chr 1:88,166,012...88,218,997
JBrowse link
zinc dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A multiple interactions ISO
EXP
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB1 mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]
CTD PMID:19714248 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Abcb6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB6 mRNA] CTD PMID:22202117 NCBI chr 1:75,171,640...75,180,392
Ensembl chr 1:75,171,717...75,180,392
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein] CTD PMID:19429256 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Aco2 aconitase 2, mitochondrial multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in decreased activity of ACO2 protein CTD PMID:16624386 NCBI chr15:81,872,463...81,915,137
Ensembl chr15:81,872,309...81,915,133
JBrowse link
G Actb actin, beta multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of ACTB mRNA CTD PMID:31588059 NCBI chr 5:142,903,115...142,907,976
Ensembl chr 5:142,903,115...142,906,754
JBrowse link
G Adam2 a disintegrin and metallopeptidase domain 2 decreases expression ISO zinc chloride results in decreased expression of ADAM2 mRNA CTD PMID:16870260 NCBI chr14:66,027,322...66,077,851
Ensembl chr14:66,027,329...66,077,733
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions
increases expression
EXP N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein] CTD PMID:18509044 NCBI chr17:57,358,581...57,483,529
Ensembl chr17:57,358,691...57,483,527
JBrowse link
G Adm adrenomedullin multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ADM mRNA] CTD PMID:22202117 NCBI chr 7:110,627,657...110,629,820
Ensembl chr 7:110,627,661...110,629,820
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO zinc chloride inhibits the reaction [N(6)-cyclohexyladenosine binds to ADORA1 protein] CTD PMID:10413299 NCBI chr 1:134,199,215...134,235,457
Ensembl chr 1:134,199,223...134,235,431
JBrowse link
G Afp alpha fetoprotein decreases expression ISO zinc chloride results in decreased expression of AFP mRNA CTD PMID:18947441 NCBI chr 5:90,490,714...90,508,907
Ensembl chr 5:90,490,737...90,508,907
JBrowse link
G Ago2 argonaute RISC catalytic subunit 2 multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of AGO2 mRNA; [Clioquinol co-treated with zinc chloride] results in decreased expression of AGO2 protein CTD PMID:22415087 NCBI chr15:73,101,625...73,184,947
Ensembl chr15:73,095,844...73,184,935
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of AK4 mRNA] CTD PMID:22202117 NCBI chr 4:101,416,478...101,467,771
Ensembl chr 4:101,419,277...101,466,995
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation
multiple interactions
EXP zinc chloride results in increased phosphorylation of AKT1 protein
wortmannin inhibits the reaction [zinc chloride results in increased phosphorylation of AKT1 protein]
CTD PMID:11340092 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Alad aminolevulinate, delta-, dehydratase multiple interactions EXP
ISO
[zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]] which affects the abundance of Mercury; zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]
lead nitrate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]; triethyllead acetate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]; zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]
zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of ALAD protein]
CTD PMID:2061546 PMID:14615064 PMID:22413763 PMID:24619859 PMID:24679358 NCBI chr 4:62,505,984...62,520,063
Ensembl chr 4:62,509,169...62,519,918
JBrowse link
G Aldoc aldolase C, fructose-bisphosphate multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ALDOC mRNA] CTD PMID:22202117 NCBI chr11:78,323,073...78,327,781
Ensembl chr11:78,322,968...78,327,781
JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney multiple interactions
increases activity
EXP
ISO
[zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of ALPL mRNA
zinc chloride results in increased activity of ALPL protein
Cadmium inhibits the reaction [zinc chloride results in increased activity of ALPL protein]; zinc chloride inhibits the reaction [Cadmium results in decreased activity of ALPL protein]
CTD PMID:19913120 PMID:26214600 NCBI chr 4:137,741,731...137,796,384
Ensembl chr 4:137,741,733...137,796,384
JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANG mRNA] CTD PMID:22202117 NCBI chr14:51,091,077...51,102,009
Ensembl chr14:51,091,150...51,102,009
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANGPTL4 mRNA] CTD PMID:22202117 NCBI chr17:33,774,900...33,781,575
Ensembl chr17:33,773,750...33,781,830
JBrowse link
G Ankrd37 ankyrin repeat domain 37 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKRD37 mRNA] CTD PMID:22202117 NCBI chr 8:45,996,908...46,000,414
Ensembl chr 8:45,996,902...46,005,707
JBrowse link
G Ankzf1 ankyrin repeat and zinc finger domain containing 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKZF1 mRNA] CTD PMID:22202117 NCBI chr 1:75,192,160...75,199,387
Ensembl chr 1:75,192,151...75,199,387
JBrowse link
G Ar androgen receptor multiple interactions ISO Androgens inhibits the reaction [zinc chloride inhibits the reaction [Androgens binds to AR protein]]; Dithiothreitol inhibits the reaction [zinc chloride inhibits the reaction [Androgens binds to AR protein]]; zinc chloride inhibits the reaction [Androgens binds to AR protein] CTD PMID:6323860 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Arg2 arginase type II increases expression ISO zinc chloride results in increased expression of ARG2 mRNA CTD PMID:18947441 NCBI chr12:79,130,788...79,156,301
Ensembl chr12:79,130,777...79,156,301
JBrowse link
G Arrb2 arrestin, beta 2 affects localization ISO zinc chloride affects the localization of ARRB2 protein CTD PMID:16959833 NCBI chr11:70,432,485...70,440,828
Ensembl chr11:70,432,635...70,440,828
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein] CTD PMID:30768131 NCBI chr 2:73,816,509...73,892,677
Ensembl chr 2:73,816,509...73,892,639
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO zinc chloride results in decreased expression of ATF4 mRNA CTD PMID:18947441 NCBI chr15:80,255,184...80,257,545
Ensembl chr15:80,255,184...80,257,541
JBrowse link
G Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 decreases expression ISO zinc chloride results in decreased expression of ATP6V1B2 mRNA CTD PMID:18947441 NCBI chr 8:69,088,736...69,113,718
Ensembl chr 8:69,088,646...69,113,711
JBrowse link
G Atp7b ATPase, Cu++ transporting, beta polypeptide decreases expression
increases expression
ISO zinc chloride results in decreased expression of ATP7B mRNA
zinc chloride results in increased expression of ATP7B mRNA
CTD PMID:18947441 NCBI chr 8:21,992,783...22,060,074
Ensembl chr 8:21,992,785...22,060,305
JBrowse link
G Bag3 BCL2-associated athanogene 3 increases expression
multiple interactions
ISO zinc chloride results in increased expression of BAG3 mRNA
zinc chloride results in increased expression of and affects the localization of BAG3 protein
CTD PMID:12706811 PMID:16870260 NCBI chr 7:128,523,583...128,546,981
Ensembl chr 7:128,523,616...128,546,981
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO
EXP
[Citric Acid co-treated with zinc chloride] results in increased expression of BAX protein
zinc chloride affects the reaction [Cadmium Chloride results in increased expression of BAX protein]
zinc chloride promotes the reaction [Doxorubicin results in increased expression of BAX mRNA]
CTD PMID:16624386 PMID:19714248 PMID:28390674 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bbc3 BCL2 binding component 3 multiple interactions EXP zinc chloride promotes the reaction [Doxorubicin results in increased expression of BBC3 mRNA] CTD PMID:19714248 NCBI chr 7:16,308,398...16,318,334
Ensembl chr 7:16,308,393...16,318,205
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO
EXP
[Citric Acid co-treated with zinc chloride] results in decreased expression of BCL2 protein; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BCL2 mRNA]; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BCL2 protein]; zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BCL2 mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of BCL2 mRNA]
CTD PMID:16624386 PMID:17786326 PMID:19714248 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b increases expression ISO zinc chloride results in increased expression of BCL2A1 mRNA CTD PMID:21540303 NCBI chr 9:89,199,273...89,207,838
Ensembl chr 9:89,199,209...89,207,827
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in decreased expression of BCL2L1 protein CTD PMID:16624386 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride affects the expression of BDNF mRNA] CTD PMID:29548726 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Bglap bone gamma carboxyglutamate protein multiple interactions EXP [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of BGLAP mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of BGLAP mRNA CTD PMID:19913120 NCBI chr 3:88,383,495...88,384,466
Ensembl chr 3:88,383,501...88,384,464
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BHLHE40 mRNA] CTD PMID:22202117 NCBI chr 6:108,660,629...108,666,925
Ensembl chr 6:108,660,629...108,666,925
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BNIP3L mRNA] CTD PMID:22202117 NCBI chr14:66,985,238...67,008,877
Ensembl chr14:66,985,239...67,008,877
JBrowse link
G Bop1 block of proliferation 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BOP1 mRNA] CTD PMID:22202117 NCBI chr15:76,452,988...76,477,249
Ensembl chr15:76,452,989...76,477,277
JBrowse link
G C3 complement component 3 increases expression ISO zinc chloride results in increased expression of C3 mRNA CTD PMID:19428942 NCBI chr17:57,203,967...57,228,136
Ensembl chr17:57,203,970...57,228,136
JBrowse link
G Cald1 caldesmon 1 increases expression ISO zinc chloride results in increased expression of CALD1 mRNA CTD PMID:16870260 NCBI chr 6:34,598,495...34,775,469
Ensembl chr 6:34,598,500...34,775,473
JBrowse link
G Car13 carbonic anhydrase 13 increases expression EXP zinc chloride results in increased expression of CAR13 mRNA CTD PMID:19000923 NCBI chr 3:14,641,727...14,663,002
Ensembl chr 3:14,641,727...14,663,002
JBrowse link
G Car9 carbonic anhydrase 9 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CA9 mRNA] CTD PMID:22202117 NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729
JBrowse link
G Casp12 caspase 12 multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in increased activity of CASP12 protein CTD PMID:16624386 NCBI chr 9:5,345,442...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in increased activity of CASP3 protein CTD PMID:16624386 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 mRNA] CTD PMID:28390674 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase multiple interactions
increases expression
increases activity
ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein]
zinc chloride results in increased expression of CAT mRNA
zinc chloride results in increased activity of CAT protein
CTD PMID:9330853 PMID:19429256 PMID:23726800 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 increases expression ISO zinc chloride results in increased expression of CCL11 mRNA CTD PMID:19428942 NCBI chr11:82,057,832...82,062,955
Ensembl chr11:82,057,823...82,062,955
JBrowse link
G Ccl17 chemokine (C-C motif) ligand 17 decreases expression ISO zinc chloride results in decreased expression of CCL17 mRNA CTD PMID:19428942 NCBI chr 8:94,809,380...94,812,038
Ensembl chr 8:94,810,453...94,812,036
JBrowse link
G Ccl19 chemokine (C-C motif) ligand 19 decreases expression ISO zinc chloride results in decreased expression of CCL19 mRNA CTD PMID:19428942 NCBI chr 4:42,754,525...42,756,365
Ensembl chr 4:42,754,525...42,756,577
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 increases expression ISO zinc chloride results in increased expression of CCL20 mRNA CTD PMID:19428942 PMID:21540303 PMID:27427241 NCBI chr 1:83,116,766...83,119,167
Ensembl chr 1:83,116,766...83,119,167
JBrowse link
G Ccl24 chemokine (C-C motif) ligand 24 decreases expression ISO zinc chloride results in decreased expression of CCL24 mRNA CTD PMID:19428942 NCBI chr 5:135,569,935...135,573,123
Ensembl chr 5:135,569,937...135,573,049
JBrowse link
G Ccl26 chemokine (C-C motif) ligand 26 increases expression ISO zinc chloride results in increased expression of CCL26 mRNA CTD PMID:19428942 NCBI chr 5:135,560,448...135,563,569
Ensembl chr 5:135,560,448...135,563,569
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 decreases expression ISO zinc chloride results in decreased expression of CCL15 mRNA CTD PMID:19428942 NCBI chr11:83,587,886...83,593,087
Ensembl chr11:83,587,882...83,593,087
JBrowse link
G Ccnb1 cyclin B1 increases expression EXP zinc chloride results in increased expression of CCNB1 mRNA CTD PMID:19000923 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Ccng1 cyclin G1 multiple interactions EXP zinc chloride affects the reaction [Cadmium Chloride results in increased expression of CCNG1 mRNA] CTD PMID:16842966 NCBI chr11:40,748,552...40,755,309
Ensembl chr11:40,748,552...40,755,311
JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CCNG2 mRNA] CTD PMID:22202117 NCBI chr 5:93,267,573...93,276,231
Ensembl chr 5:93,267,257...93,276,231
JBrowse link
G Ccr6 chemokine (C-C motif) receptor 6 decreases expression ISO zinc chloride results in decreased expression of CCR6 mRNA CTD PMID:19428942 NCBI chr17:8,236,041...8,258,519
Ensembl chr17:8,236,043...8,257,141
JBrowse link
G Ccr8 chemokine (C-C motif) receptor 8 decreases expression ISO zinc chloride results in decreased expression of CCR8 mRNA CTD PMID:19428942 NCBI chr 9:120,092,133...120,094,906
Ensembl chr 9:120,092,114...120,094,906
JBrowse link
G Cd86 CD86 antigen decreases expression EXP zinc chloride results in decreased expression of CD86 protein CTD PMID:24284788 NCBI chr16:36,568,956...36,666,158
Ensembl chr16:36,603,869...36,666,081
JBrowse link
G Cd9 CD9 antigen increases expression ISO zinc chloride results in increased expression of CD9 mRNA CTD PMID:16870260 NCBI chr 6:125,460,266...125,494,760
Ensembl chr 6:125,460,266...125,494,791
JBrowse link
G Cdh17 cadherin 17 decreases expression ISO zinc chloride results in decreased expression of CDH17 mRNA CTD PMID:18947441 NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in increased expression of CDKN1A protein CTD PMID:16624386 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO zinc chloride results in decreased expression of CDKN1B mRNA CTD PMID:21540303 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B decreases expression ISO zinc chloride results in decreased expression of CDKN2B mRNA CTD PMID:21540303 NCBI chr 4:89,306,289...89,311,032
Ensembl chr 4:89,306,299...89,311,039
JBrowse link
G Cdr1 cerebellar degeneration related antigen 1 decreases expression ISO zinc chloride results in decreased expression of CDR1 mRNA CTD PMID:16870260 NCBI chr  X:61,183,246...61,185,558
Ensembl chr  X:61,184,005...61,185,558
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator increases expression ISO zinc chloride results in increased expression of CFTR mRNA CTD PMID:16870260 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link
G Chek1 checkpoint kinase 1 increases expression EXP zinc chloride results in increased expression of CHEK1 mRNA CTD PMID:19000923 NCBI chr 9:36,708,482...36,726,658
Ensembl chr 9:36,708,482...36,727,065
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CITED2 mRNA] CTD PMID:22202117 NCBI chr10:17,723,228...17,725,674
Ensembl chr10:17,723,218...17,725,674
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions EXP [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of COL1A1 mRNA CTD PMID:19913120 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Commd1 COMM domain containing 1 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 NCBI chr11:22,899,728...22,984,539
Ensembl chr11:22,896,136...22,982,382
JBrowse link
G Cox17 cytochrome c oxidase assembly protein 17, copper chaperone decreases expression ISO zinc chloride results in decreased expression of COX17 mRNA CTD PMID:18947441 NCBI chr16:38,346,983...38,352,763
Ensembl chr16:38,346,991...38,352,763
Ensembl chr16:38,346,991...38,352,763
JBrowse link
G Cp ceruloplasmin increases expression ISO zinc chloride results in increased expression of CP mRNA CTD PMID:18947441 NCBI chr 3:19,956,933...20,009,750
Ensembl chr 3:19,957,054...20,009,145
JBrowse link
G Cps1 carbamoyl-phosphate synthetase 1 increases expression ISO zinc chloride results in increased expression of CPS1 mRNA CTD PMID:16870260 NCBI chr 1:67,122,426...67,231,267
Ensembl chr 1:67,123,026...67,231,259
JBrowse link
G Crp C-reactive protein, pentraxin-related increases expression ISO zinc chloride results in increased expression of CRP mRNA CTD PMID:19428942 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) increases expression
multiple interactions
ISO
EXP
zinc chloride results in increased expression of CSF2 mRNA
zinc chloride results in increased expression of CSF2 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]
CTD PMID:18509044 PMID:21540303 PMID:27427241 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CSRP2 mRNA] CTD PMID:22202117 NCBI chr10:110,920,176...110,939,514
Ensembl chr10:110,919,789...110,939,622
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 increases expression ISO zinc chloride results in increased expression of CXCL1 mRNA CTD PMID:19428942 NCBI chr 5:90,891,245...90,893,121
Ensembl chr 5:90,891,241...90,893,115
JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 increases expression ISO zinc chloride results in increased expression of CXCL11 mRNA CTD PMID:19428942 NCBI chr 5:92,359,544...92,363,296
Ensembl chr 5:92,359,544...92,365,485
JBrowse link
G Cxcl13 chemokine (C-X-C motif) ligand 13 decreases expression ISO zinc chloride results in decreased expression of CXCL13 mRNA CTD PMID:19428942 NCBI chr 5:95,956,939...95,961,068
Ensembl chr 5:95,956,951...95,961,068
JBrowse link
G Cxcl14 chemokine (C-X-C motif) ligand 14 increases expression ISO zinc chloride results in increased expression of CXCL14 mRNA CTD PMID:19428942 NCBI chr13:56,288,643...56,296,811
Ensembl chr13:56,288,643...56,296,551
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases expression
multiple interactions
increases secretion
ISO zinc chloride results in increased expression of CXCL8 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; DUOX1 protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; pyrazolanthrone inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; Thiourea inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]
CTD PMID:19428942 PMID:21540303 PMID:21842098 PMID:23692033 PMID:27427241 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 increases expression ISO zinc chloride results in increased expression of CXCL1 mRNA CTD PMID:19428942 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600
JBrowse link
G Cxcl5 chemokine (C-X-C motif) ligand 5 decreases expression ISO zinc chloride results in decreased expression of CXCL6 mRNA CTD PMID:19428942 NCBI chr 5:90,759,298...90,761,625
Ensembl chr 5:90,759,360...90,761,624
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases stability
multiple interactions
EXP zinc chloride results in increased stability of CYP1A1 mRNA; zinc chloride results in increased stability of CYP1A1 protein
zinc chloride inhibits the reaction [1,10-phenanthroline inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]
CTD PMID:19896525 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Dcp1b decapping mRNA 1B multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of DCP1B mRNA CTD PMID:22415087 NCBI chr 6:119,175,253...119,221,614
Ensembl chr 6:119,175,253...119,221,616
JBrowse link
G Ddx21 DExD box helicase 21 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of DDX21 mRNA] CTD PMID:22202117 NCBI chr10:62,580,247...62,602,298
Ensembl chr10:62,580,251...62,602,281
JBrowse link
G Denn2b DENN domain containing 2B increases expression ISO zinc chloride results in increased expression of DENND2B mRNA CTD PMID:16870260 NCBI chr 7:109,523,911...109,703,718
Ensembl chr 7:109,523,911...109,703,605
JBrowse link
G Dhrs2 dehydrogenase/reductase member 2 increases expression ISO zinc chloride results in increased expression of DHRS2 mRNA CTD PMID:16870260 NCBI chr14:55,222,007...55,241,440
Ensembl chr14:55,222,007...55,241,435
JBrowse link
G Dicer1 dicer 1, ribonuclease type III multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of DICER1 protein CTD PMID:22415087 NCBI chr12:104,687,740...104,751,968
Ensembl chr12:104,687,742...104,751,952
JBrowse link
G Dll4 delta like canonical Notch ligand 4 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of DLL4 mRNA CTD PMID:31588059 NCBI chr 2:119,325,784...119,335,666
Ensembl chr 2:119,325,784...119,335,962
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO zinc chloride inhibits the reaction [ecopipam binds to DRD1 protein]; zinc chloride inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9109525 NCBI chr13:54,051,183...54,055,658
Ensembl chr13:54,051,183...54,055,705
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO zinc chloride inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein] CTD PMID:9109525 NCBI chr 9:49,340,360...49,408,177
Ensembl chr 9:49,340,627...49,408,177
JBrowse link
G Drosha drosha, ribonuclease type III multiple interactions ISO [Clioquinol co-treated with zinc chloride] affects the expression of DROSHA protein CTD PMID:22415087 NCBI chr15:12,824,804...12,935,291
Ensembl chr15:12,824,815...12,935,291
JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO DUOX1 protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein] CTD PMID:27427241 NCBI chr 2:122,313,010...122,347,972
Ensembl chr 2:122,315,672...122,347,972
JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation ISO zinc chloride results in increased phosphorylation of EGFR protein CTD PMID:21540303 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EGLN1 mRNA]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein] CTD PMID:16579968 PMID:22202117 NCBI chr 8:124,908,587...124,949,254
Ensembl chr 8:124,908,587...124,949,324
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E mRNA; [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E protein CTD PMID:22415087 NCBI chr 3:138,526,191...138,559,696
Ensembl chr 3:138,526,179...138,559,696
JBrowse link
G Elk1 ELK1, member of ETS oncogene family multiple interactions
increases activity
ISO zinc chloride results in increased phosphorylation of and results in increased activity of ELK1 protein
zinc chloride results in increased activity of ELK1 protein
CTD PMID:16960431 PMID:20412391 NCBI chr  X:20,933,395...20,950,608
Ensembl chr  X:20,933,395...20,950,608
JBrowse link
G Eno2 enolase 2, gamma neuronal multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ENO2 mRNA] CTD PMID:22202117 NCBI chr 6:124,760,053...124,769,673
Ensembl chr 6:124,760,053...124,769,673
JBrowse link
G Epo erythropoietin multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EPO protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA] CTD PMID:11090055 NCBI chr 5:137,483,020...137,485,816
Ensembl chr 5:137,483,020...137,533,242
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 decreases expression ISO zinc chloride results in decreased expression of F2RL2 mRNA CTD PMID:16870260 NCBI chr13:95,696,920...95,702,768
Ensembl chr13:95,696,853...95,702,739
JBrowse link
G Fabp1 fatty acid binding protein 1, liver decreases expression ISO zinc chloride results in decreased expression of FABP1 mRNA CTD PMID:18947441 NCBI chr 6:71,199,879...71,205,034
Ensembl chr 6:71,199,827...71,205,023
JBrowse link
G Fam162a family with sequence similarity 162, member A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of FAM162A mRNA] CTD PMID:22202117 NCBI chr16:36,043,844...36,071,561
Ensembl chr16:36,043,761...36,071,594
JBrowse link
G Fasn fatty acid synthase decreases expression ISO zinc chloride results in decreased expression of FASN mRNA CTD PMID:21540303 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of FOS mRNA] CTD PMID:22202117 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Fosl1 fos-like antigen 1 increases expression EXP zinc chloride results in increased expression of FOSL1 mRNA CTD PMID:19000923 NCBI chr19:5,447,698...5,455,938
Ensembl chr19:5,447,547...5,455,946
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO zinc chloride results in decreased expression of FOXA2 mRNA CTD PMID:21540303 NCBI chr 2:148,042,877...148,046,969
Ensembl chr 2:148,042,877...148,046,969
JBrowse link
G Foxd1 forkhead box D1 increases expression ISO zinc chloride results in increased expression of FOXD1 mRNA CTD PMID:16870260 NCBI chr13:98,354,245...98,356,705
Ensembl chr13:98,354,242...98,359,305
JBrowse link
G G6pc glucose-6-phosphatase, catalytic multiple interactions ISO zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of G6PC1 protein] CTD PMID:22413763 NCBI chr11:101,367,716...101,377,903
Ensembl chr11:101,367,561...101,377,903
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein] CTD PMID:18972399 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression ISO zinc chloride results in increased expression of GADD45A mRNA CTD PMID:33645215 NCBI chr 6:67,035,096...67,037,407
Ensembl chr 6:67,035,096...67,037,457
JBrowse link
G Gbe1 glucan (1,4-alpha-), branching enzyme 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of GBE1 mRNA] CTD PMID:22202117 NCBI chr16:70,313,949...70,569,720
Ensembl chr16:70,313,949...70,569,716
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLC mRNA]
zinc chloride results in increased expression of GCLC mRNA
CTD PMID:18385089 PMID:33645215 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions ISO zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA] CTD PMID:18385089 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO zinc chloride results in increased expression of GPX2 mRNA CTD PMID:18947441 NCBI chr12:76,792,335...76,795,554
Ensembl chr12:76,792,333...76,795,554
JBrowse link
G Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) increases expression ISO zinc chloride results in increased expression of GRIK2 mRNA CTD PMID:16870260 NCBI chr10:49,093,680...49,790,161
Ensembl chr10:49,094,833...49,788,766
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) multiple interactions ISO AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of GRIN2A protein]; zinc chloride results in increased expression of and results in increased phosphorylation of GRIN2A protein CTD PMID:12211081 NCBI chr16:9,567,901...9,996,083
Ensembl chr16:9,567,898...9,995,560
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) multiple interactions ISO AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of GRIN2B protein]; zinc chloride results in increased expression of and results in increased phosphorylation of GRIN2B protein CTD PMID:12211081 NCBI chr 6:135,713,221...136,173,615
Ensembl chr 6:135,713,233...136,173,511
JBrowse link
G Grm5 glutamate receptor, metabotropic 5 multiple interactions
increases expression
ISO Copper inhibits the reaction [zinc chloride results in increased expression of GRM5 protein] CTD PMID:25007851 NCBI chr 7:87,583,981...88,135,063
Ensembl chr 7:87,584,168...88,134,907
JBrowse link
G Gsr glutathione reductase multiple interactions ISO [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to zinc chloride
zinc chloride inhibits the reaction [Cadmium Chloride results in increased activity of GSR protein]; zinc chloride inhibits the reaction [Copper results in decreased activity of GSR protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]
CTD PMID:12632252 PMID:19429256 PMID:20600438 PMID:23726800 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO [Cadmium Chloride co-treated with zinc chloride] results in increased expression of GSTP1 protein CTD PMID:15602745 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985
JBrowse link
G Gys1 glycogen synthase 1, muscle multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of GYS1 mRNA] CTD PMID:22202117 NCBI chr 7:45,434,839...45,456,617
Ensembl chr 7:45,434,844...45,456,619
JBrowse link
G H2ax H2A.X variant histone increases expression ISO zinc chloride results in increased expression of H2AX mRNA CTD PMID:18947441 NCBI chr 9:44,334,715...44,336,077
Ensembl chr 9:44,334,694...44,336,077
JBrowse link
G Hcfc1r1 host cell factor C1 regulator 1 (XPO1-dependent) multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HCFC1R1 mRNA] CTD PMID:22202117 NCBI chr17:23,673,608...23,675,524
Ensembl chr17:23,673,596...23,675,227
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of HDAC1 mRNA CTD PMID:31588059 NCBI chr 4:129,516,104...129,542,646
Ensembl chr 4:129,516,104...129,542,713
JBrowse link
G Hells helicase, lymphoid specific increases expression EXP zinc chloride results in increased expression of HELLS mRNA CTD PMID:19000923 NCBI chr19:38,930,262...38,970,470
Ensembl chr19:38,930,915...38,971,051
JBrowse link
G Heph hephaestin decreases expression ISO zinc chloride results in decreased expression of HEPH mRNA CTD PMID:18947441 NCBI chr  X:96,455,436...96,574,485
Ensembl chr  X:96,455,359...96,574,485
JBrowse link
G Hexb hexosaminidase B multiple interactions ISO zinc chloride inhibits the reaction [2-phenylphenol results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [bitertanol results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Butylated Hydroxyanisole results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Butylated Hydroxytoluene results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [butylparaben results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [EPN oxon results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Permethrin results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [prothiophos results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [pyridaben results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [salinomycin results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [terbufos results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr13:97,176,331...97,198,357
Ensembl chr13:97,176,331...97,198,357
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions
increases expression
affects splicing
ISO
EXP
Cycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form]; zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]; zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
[Doxorubicin co-treated with zinc chloride] results in decreased expression of HIF1A mRNA
zinc chloride results in increased expression of HIF1A mRNA; zinc chloride results in increased expression of HIF1A mRNA alternative form; zinc chloride results in increased expression of HIF1A protein alternative form
zinc chloride affects the splicing of HIF1A mRNA
CTD PMID:11090055 PMID:11739637 PMID:16579968 PMID:19714248 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hilpda hypoxia inducible lipid droplet associated multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HILPDA mRNA] CTD PMID:22202117 NCBI chr 6:29,272,488...29,275,449
Ensembl chr 6:29,272,488...29,275,446
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 multiple interactions ISO
EXP
zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of HIPK2 protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in decreased expression of HIPK2 protein]
[Doxorubicin co-treated with zinc chloride] results in increased expression of HIPK2 mRNA
CTD PMID:19714248 NCBI chr 6:38,687,512...38,876,331
Ensembl chr 6:38,694,390...38,876,165
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HK2 mRNA] CTD PMID:22202117 NCBI chr 6:82,725,025...82,774,454
Ensembl chr 6:82,725,025...82,774,454
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
zinc chloride results in increased expression of HMOX1 mRNA; zinc chloride results in increased expression of HMOX1 protein
HMOX1 enhancer affects the reaction [zinc chloride results in increased expression of HMOX1 mRNA]
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HMOX1 mRNA]
CTD PMID:7538129 PMID:16870260 PMID:22202117 PMID:27427241 PMID:33645215 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hspa1a heat shock protein 1A increases expression ISO
EXP
zinc chloride results in increased expression of HSPA1A mRNA CTD PMID:12085988 PMID:16870260 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspa1b heat shock protein 1B increases expression EXP zinc chloride results in increased expression of HSPA1B mRNA CTD PMID:12085988 NCBI chr17:34,956,429...34,959,238
Ensembl chr17:34,956,436...34,959,238
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) increases expression ISO zinc chloride results in increased expression of HSPD1 protein CTD PMID:19429256 NCBI chr 1:55,077,833...55,088,243
Ensembl chr 1:55,077,835...55,088,243
JBrowse link
G Ifna2 interferon alpha 2 decreases expression ISO zinc chloride results in decreased expression of IFNA2 mRNA CTD PMID:19428942 NCBI chr 4:88,683,207...88,683,779
Ensembl chr 4:88,682,881...88,683,912
JBrowse link
G Ifng interferon gamma multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of IFNG mRNA; zinc chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 PMID:31588059 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta decreases expression ISO zinc chloride results in decreased expression of IKBKB mRNA CTD PMID:21540303 NCBI chr 8:22,659,205...22,706,589
Ensembl chr 8:22,659,212...22,706,589
JBrowse link
G Il10 interleukin 10 increases expression EXP zinc chloride results in increased expression of IL10 mRNA CTD PMID:24284788 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il10rb interleukin 10 receptor, beta decreases expression ISO zinc chloride results in decreased expression of IL10RB mRNA CTD PMID:19428942 NCBI chr16:91,406,157...91,425,834
Ensembl chr16:91,406,164...91,425,834
JBrowse link
G Il12b interleukin 12b decreases expression EXP zinc chloride results in decreased expression of IL12B mRNA CTD PMID:24284788 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il18r1 interleukin 18 receptor 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of IL18R1 mRNA] CTD PMID:22202117 NCBI chr 1:40,465,552...40,500,854
Ensembl chr 1:40,465,552...40,500,854
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
EXP zinc chloride results in increased expression of IL1A protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]
CTD PMID:18509044 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP
ISO
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
zinc chloride results in increased expression of IL1B mRNA
zinc chloride inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
CTD PMID:9138684 PMID:18509044 PMID:19130485 PMID:27427241 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression EXP zinc chloride results in increased expression of IL1RL1 mRNA CTD PMID:19000923 NCBI chr 1:40,404,864...40,465,418
Ensembl chr 1:40,429,570...40,465,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO zinc chloride results in increased expression of IL1RN mRNA CTD PMID:19428942 NCBI chr 2:24,336,860...24,351,491
Ensembl chr 2:24,336,853...24,351,494
JBrowse link
G Il3 interleukin 3 multiple interactions
increases expression
EXP N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein] CTD PMID:18509044 NCBI chr11:54,265,085...54,267,279
Ensembl chr11:54,265,303...54,267,277
JBrowse link
G Il36rn interleukin 36 receptor antagonist decreases expression ISO zinc chloride results in decreased expression of IL36RN mRNA CTD PMID:19428942 NCBI chr 2:24,276,954...24,282,432
Ensembl chr 2:24,276,954...24,283,426
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
increases expression
ISO zinc chloride results in increased secretion of IL6 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of IL6 protein]; Thiourea inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]
zinc chloride results in increased expression of IL6 mRNA
CTD PMID:21842098 PMID:27427241 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Insig2 insulin induced gene 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of INSIG2 mRNA] CTD PMID:22202117 NCBI chr 1:121,304,353...121,332,662
Ensembl chr 1:121,304,353...121,332,589
JBrowse link
G Insr insulin receptor increases phosphorylation EXP zinc chloride results in increased phosphorylation of INSR protein CTD PMID:11340092 NCBI chr 8:3,150,922...3,279,649
Ensembl chr 8:3,122,061...3,279,617
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression ISO zinc chloride results in increased expression of IREB2 mRNA CTD PMID:18947441 NCBI chr 9:54,862,658...54,912,534
Ensembl chr 9:54,863,789...54,912,530
JBrowse link
G Itgb6 integrin beta 6 increases expression ISO zinc chloride results in increased expression of ITGB6 mRNA CTD PMID:16870260 NCBI chr 2:60,598,292...60,722,603
Ensembl chr 2:60,598,292...60,722,643
JBrowse link
G Jun jun proto-oncogene increases expression
multiple interactions
ISO
EXP
zinc chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [zinc chloride results in increased expression of JUN mRNA]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
CTD PMID:11306679 PMID:19000923 PMID:21540303 PMID:30768131 PMID:33645215 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Junb jun B proto-oncogene increases expression EXP zinc chloride results in increased expression of JUNB mRNA CTD PMID:19000923 NCBI chr 8:84,976,909...84,978,748
Ensembl chr 8:84,974,484...84,978,718
Ensembl chr 8:84,974,484...84,978,718
JBrowse link
G Kat5 K(lysine) acetyltransferase 5 multiple interactions ISO zinc chloride affects the reaction [4-aminophenylarsenoxide binds to KAT5 protein] CTD PMID:28837777 NCBI chr19:5,603,014...5,611,556
Ensembl chr19:5,603,014...5,610,237
JBrowse link
G Kdm3a lysine (K)-specific demethylase 3A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of KDM3A mRNA] CTD PMID:22202117 NCBI chr 6:71,588,970...71,632,990
Ensembl chr 6:71,588,972...71,632,990
JBrowse link
G Kdm4b lysine (K)-specific demethylase 4B multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of KDM4B mRNA] CTD PMID:22202117 NCBI chr17:56,325,970...56,403,774
Ensembl chr17:56,326,062...56,402,870
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions
affects folding
EXP zinc chloride promotes the reaction [KEAP1 protein binds to KEAP1 protein]
zinc chloride affects the folding of KEAP1 protein
CTD PMID:30261176 NCBI chr 9:21,229,730...21,239,332
Ensembl chr 9:21,229,730...21,239,361
JBrowse link
G Kif5a kinesin family member 5A decreases activity
multiple interactions
ISO zinc chloride results in decreased activity of KIF5A protein
Adenosine Triphosphate inhibits the reaction [zinc chloride results in decreased activity of KIF5A protein]; Magnesium Chloride affects the reaction [zinc chloride results in decreased activity of KIF5A protein]
CTD PMID:28122263 NCBI chr10:127,225,695...127,266,348
Ensembl chr10:127,225,696...127,263,348
JBrowse link
G Lep leptin increases expression ISO zinc chloride results in increased expression of LEP mRNA CTD PMID:21540303 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Limch1 LIM and calponin homology domains 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of LIMCH1 mRNA] CTD PMID:22202117 NCBI chr 5:66,745,889...67,057,159
Ensembl chr 5:66,745,827...67,057,158
JBrowse link
G Lta lymphotoxin A decreases expression
increases expression
ISO zinc chloride results in decreased expression of LTA mRNA
zinc chloride results in increased expression of LTA mRNA
CTD PMID:19428942 PMID:21540303 NCBI chr17:35,203,165...35,205,578
Ensembl chr17:35,203,165...35,205,351
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 decreases expression ISO zinc chloride results in decreased expression of LTB4R mRNA CTD PMID:19428942 NCBI chr14:55,765,962...55,768,492
Ensembl chr14:55,765,962...55,768,494
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of MAFF mRNA] CTD PMID:22202117 NCBI chr15:79,346,621...79,359,078
Ensembl chr15:79,346,621...79,359,076
JBrowse link
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) increases expression ISO zinc chloride results in increased expression of MAFG mRNA CTD PMID:11162468 NCBI chr11:120,625,117...120,634,955
Ensembl chr11:120,625,117...120,633,600
JBrowse link
G Maml1 mastermind like transcriptional coactivator 1 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of MAML1 mRNA CTD PMID:31588059 NCBI chr11:50,255,634...50,293,131
Ensembl chr11:50,255,634...50,292,311
JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 increases activity EXP zinc chloride results in increased activity of MAP2K4 protein CTD PMID:11306679 NCBI chr11:65,688,244...65,788,359
Ensembl chr11:65,688,243...65,788,297
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 multiple interactions
increases activity
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAP3K1 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAP3K1 protein] CTD PMID:11306679 NCBI chr13:111,746,428...111,818,269
Ensembl chr13:111,746,428...111,808,993
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
N,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein
zinc chloride results in increased activity of MAPK1 protein
CTD PMID:11306679 PMID:11551972 PMID:16960431 PMID:20412391 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; N,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; Vanadates promotes the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16960431 PMID:20412391 PMID:21575692 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]; [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; Acetylcysteine inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]; RAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]; zinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:11306679 PMID:20423716 PMID:30768131 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP zinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK9 protein] CTD PMID:20423716 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression EXP zinc chloride results in increased expression of MCM3 mRNA CTD PMID:19000923 NCBI chr 1:20,802,966...20,820,312
Ensembl chr 1:20,802,968...20,820,312
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) decreases expression ISO zinc chloride results in decreased expression of MIF mRNA CTD PMID:18947441 NCBI chr10:75,859,353...75,860,277
Ensembl chr10:75,859,353...75,860,240
JBrowse link
G Mir130a microRNA 130a multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR130A mRNA CTD PMID:22415087 NCBI chr 2:84,741,115...84,741,178
Ensembl chr 2:84,741,115...84,741,178
JBrowse link
G Mir15a microRNA 15a multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR15A mRNA CTD PMID:22415087 NCBI chr14:61,632,027...61,632,110
Ensembl chr14:61,632,027...61,632,110
JBrowse link
G Mir223 microRNA 223 multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR223 mRNA CTD PMID:22415087 NCBI chr  X:96,242,817...96,242,926
Ensembl chr  X:96,242,817...96,242,926
JBrowse link
G Mir29a microRNA 29a multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR29A mRNA CTD PMID:22415087 NCBI chr 6:31,062,660...31,062,747
Ensembl chr 6:31,062,660...31,062,747
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein] CTD PMID:21573219 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO zinc chloride results in decreased expression of MMP7 mRNA CTD PMID:21540303 NCBI chr 9:7,692,090...7,699,585
Ensembl chr 9:7,692,090...7,699,585
JBrowse link
G Mt1 metallothionein 1 affects binding
increases expression
multiple interactions
affects response to substance
decreases expression
EXP
ISO
zinc chloride binds to MT1 protein
zinc chloride results in increased expression of MT1X mRNA
epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of MT1X mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [zinc chloride results in increased expression of MT1X mRNA]
zinc chloride results in increased expression of MT1A mRNA; zinc chloride results in increased expression of MT1A protein
zinc chloride promotes the reaction [Glucose results in increased expression of MT1A mRNA]
MT1 affects the susceptibility to zinc chloride
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; bisindolylmaleimide I inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Dicumarol inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]; Genistein inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Ro 31-8220 inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Sodium Selenite inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; wortmannin inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]
zinc chloride results in increased expression of MT1 mRNA; zinc chloride results in increased expression of MT1 protein
zinc chloride results in decreased expression of MT1 protein
CTD PMID:3422486 PMID:8928928 PMID:11551972 PMID:14998373 PMID:15288509 More... NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Mt2 metallothionein 2 affects binding
multiple interactions
increases expression
affects response to substance
EXP
ISO
zinc chloride binds to MT2 protein
zinc chloride promotes the reaction [Glucose results in increased expression of MT2A mRNA]
zinc chloride results in increased expression of MT2A mRNA; zinc chloride results in increased expression of MT2A protein
[zinc chloride co-treated with pyrithione zinc] results in increased expression of MT2A mRNA; Dactinomycin inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; zinc chloride inhibits the reaction [Lipopolysaccharides results in increased expression of MT2A mRNA]
MT2 affects the susceptibility to zinc chloride
zinc chloride promotes the reaction [Cadmium Chloride results in increased expression of MT2 mRNA]
zinc chloride results in increased expression of MT2 mRNA; zinc chloride results in increased expression of MT2 protein
CTD PMID:9138684 PMID:15288509 PMID:16842966 PMID:16870260 PMID:16987576 More... NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Mt3 metallothionein 3 increases expression ISO zinc chloride results in increased expression of MT3 mRNA CTD PMID:18947441 NCBI chr 8:94,152,607...94,154,148
Ensembl chr 8:94,152,607...94,154,146
JBrowse link
G Mta2 metastasis-associated gene family, member 2 decreases expression ISO zinc chloride results in decreased expression of MTA2 mRNA CTD PMID:16870260 NCBI chr19:8,941,920...8,952,300
Ensembl chr19:8,941,875...8,952,303
JBrowse link
G Mtf1 metal response element binding transcription factor 1 multiple interactions
affects localization
decreases expression
EXP
ISO
zinc chloride results in increased phosphorylation of and results in increased activity of MTF1 protein
zinc chloride affects the localization of MTF1 protein
zinc chloride results in decreased expression of MTF1 mRNA
CTD PMID:11551972 PMID:16423564 PMID:18947441 NCBI chr 4:124,802,549...124,849,800
Ensembl chr 4:124,802,104...124,849,800
JBrowse link
G Mtf2 metal response element binding transcription factor 2 decreases expression ISO zinc chloride results in decreased expression of MTF2 mRNA CTD PMID:18947441 NCBI chr 5:108,065,660...108,109,219
Ensembl chr 5:108,065,674...108,109,004
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases response to substance
EXP NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]
NCF1 results in increased susceptibility to zinc chloride
CTD PMID:18509044 NCBI chr 5:134,220,053...134,229,628
Ensembl chr 5:134,220,053...134,229,625
JBrowse link
G Ndrg1 N-myc downstream regulated gene 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of NDRG1 mRNA] CTD PMID:22202117 NCBI chr15:66,929,318...66,969,641
Ensembl chr15:66,929,318...66,969,640
JBrowse link
G Ndufaf5 NADH:ubiquinone oxidoreductase complex assembly factor 5 decreases expression ISO zinc chloride results in decreased expression of NDUFAF5 mRNA CTD PMID:16870260 NCBI chr 2:140,170,584...140,218,965
Ensembl chr 2:140,170,649...140,203,689
JBrowse link
G Nf2 neurofibromin 2 decreases expression ISO zinc chloride results in decreased expression of NF2 mRNA CTD PMID:16870260 NCBI chr11:4,757,639...4,849,544
Ensembl chr11:4,765,845...4,849,536
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects response to substance
multiple interactions
EXP
ISO
[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to zinc chloride
zinc chloride promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]
CTD PMID:18385089 PMID:19303893 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 increases activity ISO zinc chloride results in increased activity of NFKB1 protein CTD PMID:21842098 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
G Nip7 NIP7, nucleolar pre-rRNA processing protein multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of NIP7 mRNA] CTD PMID:22202117 NCBI chr 8:107,056,877...107,060,931
Ensembl chr 8:107,056,877...107,060,931
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of NMNAT1 mRNA CTD PMID:31588059 NCBI chr 4:149,467,569...149,485,210
Ensembl chr 4:149,467,572...149,485,202
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP zinc chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nox4 NADPH oxidase 4 increases expression ISO zinc chloride results in increased expression of NOX4 mRNA CTD PMID:16870260 NCBI chr 7:87,244,430...87,398,710
Ensembl chr 7:87,246,096...87,398,710
JBrowse link
G Ntn3 netrin 3 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of NTN3 mRNA CTD PMID:31588059 NCBI chr17:24,203,831...24,209,387
Ensembl chr17:24,203,848...24,209,531
JBrowse link
G Olfr1128 olfactory receptor 1128 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OLFR1128 mRNA CTD PMID:31588059 NCBI chr 2:87,544,607...87,545,542
Ensembl chr 2:87,544,607...87,545,542
JBrowse link
G Olfr1199 olfactory receptor 1199 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OLFR1199 mRNA CTD PMID:31588059 NCBI chr 2:88,755,741...88,760,485
Ensembl chr 2:88,754,195...88,760,469
JBrowse link
G Olfr1259 olfactory receptor 1259 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OLFR1259 mRNA CTD PMID:31588059 NCBI chr 2:89,943,184...89,944,113
Ensembl chr 2:89,940,532...89,948,664
JBrowse link
G Olfr1318 olfactory receptor 1318 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR1318 mRNA CTD PMID:31588059 NCBI chr 2:112,155,898...112,157,007
Ensembl chr 2:112,154,198...112,159,157
JBrowse link
G Olfr1348 olfactory receptor 1348 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR1348 mRNA CTD PMID:31588059 NCBI chr 7:6,501,286...6,502,224
Ensembl chr 7:6,499,793...6,508,748
JBrowse link
G Olfr1413 olfactory receptor 1413 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR1413 mRNA CTD PMID:31588059 NCBI chr 1:92,573,125...92,574,206
Ensembl chr 1:92,571,322...92,574,397
JBrowse link
G Olfr1495 olfactory receptor 1495 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR1495 mRNA CTD PMID:31588059 NCBI chr19:13,768,344...13,769,303
Ensembl chr19:13,764,606...13,770,248
JBrowse link
G Olfr153 olfactory receptor 153 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OLFR153 mRNA CTD PMID:31588059 NCBI chr 2:87,532,035...87,532,958
Ensembl chr 2:87,531,796...87,533,053
JBrowse link
G Olfr393 olfactory receptor 393 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR393 mRNA CTD PMID:31588059 NCBI chr11:73,847,185...73,848,123
Ensembl chr11:73,844,413...73,851,454
JBrowse link
G Olfr401 olfactory receptor 401 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OLFR401 mRNA CTD PMID:31588059 NCBI chr11:74,121,291...74,122,238
Ensembl chr11:74,113,712...74,122,941
JBrowse link
G Olfr484 olfactory receptor 484 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OLFR484 mRNA CTD PMID:31588059 NCBI chr 7:108,124,296...108,125,261
Ensembl chr 7:108,120,691...108,127,449
JBrowse link
G Olfr535 olfactory receptor 535 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR535 mRNA CTD PMID:31588059 NCBI chr 7:140,492,640...140,493,578
Ensembl chr 7:140,484,216...140,497,104
JBrowse link
G Olfr550 olfactory receptor 550 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR550 mRNA CTD PMID:31588059 NCBI chr 7:102,571,431...102,579,662
Ensembl chr 7:102,571,442...102,583,011
JBrowse link
G Olfr61 olfactory receptor 61 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OLFR61 mRNA CTD PMID:31588059 NCBI chr 7:140,637,703...140,638,638
Ensembl chr 7:140,628,970...140,638,798
JBrowse link
G Olfr706 olfactory receptor 706 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR706 mRNA CTD PMID:31588059 NCBI chr 7:106,885,865...106,886,815
Ensembl chr 7:106,882,589...106,888,162
JBrowse link
G Olfr811 olfactory receptor 811 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR811 mRNA CTD PMID:31588059 NCBI chr10:129,801,564...129,802,523
Ensembl chr10:129,800,615...129,804,396
JBrowse link
G Olfr818 olfactory receptor 818 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR818 mRNA CTD PMID:31588059 NCBI chr10:129,945,104...129,946,060
Ensembl chr10:129,944,396...129,949,100
JBrowse link
G Olfr887 olfactory receptor 887 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR887 mRNA CTD PMID:31588059 NCBI chr 9:38,084,838...38,085,767
Ensembl chr 9:38,084,072...38,090,737
JBrowse link
G Olfr893 olfactory receptor 893 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR893 mRNA CTD PMID:31588059 NCBI chr 9:38,209,052...38,209,993
Ensembl chr 9:38,208,365...38,211,598
JBrowse link
G Olfr907 olfactory receptor 907 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR907 mRNA CTD PMID:31588059 NCBI chr 9:38,498,671...38,499,603
Ensembl chr 9:38,495,801...38,499,882
JBrowse link
G Olfr908 olfactory receptor 908 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of OLFR908 mRNA CTD PMID:31588059 NCBI chr 9:38,516,034...38,516,965
Ensembl chr 9:38,516,034...38,516,965
JBrowse link
G Olfr92 olfactory receptor 92 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OLFR92 mRNA CTD PMID:31588059 NCBI chr17:37,111,042...37,111,980
Ensembl chr17:37,110,512...37,120,088
JBrowse link
G Orm1 orosomucoid 1 increases expression EXP zinc chloride results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 4:63,344,556...63,348,163
Ensembl chr 4:63,344,560...63,348,163
JBrowse link
G Orm2 orosomucoid 2 increases expression EXP zinc chloride results in increased expression of ORM2 mRNA CTD PMID:19000923 NCBI chr 4:63,362,449...63,365,877
Ensembl chr 4:63,362,449...63,365,878
JBrowse link
G P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 multiple interactions ISO zinc chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr 5:110,339,812...110,343,320
Ensembl chr 5:110,339,812...110,343,212
JBrowse link
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of P4HA1 mRNA] CTD PMID:22202117 NCBI chr10:59,323,197...59,373,304
Ensembl chr10:59,323,296...59,373,304
JBrowse link
G P4ha2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of P4HA2 mRNA] CTD PMID:22202117 NCBI chr11:54,100,924...54,131,668
Ensembl chr11:54,100,095...54,131,665
JBrowse link
G Paip1 polyadenylate binding protein-interacting protein 1 decreases expression ISO zinc chloride results in decreased expression of PAIP1 mRNA CTD PMID:18947441 NCBI chr13:119,428,331...119,460,323
Ensembl chr13:119,428,601...119,458,218
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases expression
increases activity
increases response to substance
ISO
EXP
zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]; zinc chloride inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]; zinc chloride promotes the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]
zinc chloride results in increased expression of PARP1 protein
zinc chloride results in increased activity of PARP1 protein
PARP1 results in increased susceptibility to zinc chloride
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; Cibacron Blue F 3GA inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; coomassie Brilliant Blue inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; periodate-oxidized adenosine 5'-triphosphate inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]
CTD PMID:18509044 PMID:19056730 PMID:19714248 PMID:22253048 PMID:33645215 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pcbd1 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 increases expression ISO zinc chloride results in increased expression of PCBD1 mRNA CTD PMID:18947441 NCBI chr10:61,089,331...61,094,329
Ensembl chr10:61,089,331...61,094,324
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [Cadmium Chloride co-treated with zinc chloride] results in increased expression of PCNA protein CTD PMID:15602745 NCBI chr 2:132,249,286...132,253,180
Ensembl chr 2:132,249,162...132,253,314
JBrowse link
G Pdap1 PDGFA associated protein 1 multiple interactions EXP zinc chloride promotes the reaction [Cadmium Chloride results in increased expression of PDAP1 mRNA] CTD PMID:16842966 NCBI chr 5:145,128,770...145,140,025
Ensembl chr 5:145,128,769...145,140,238
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] CTD PMID:22202117 NCBI chr 2:71,873,215...71,903,858
Ensembl chr 2:71,873,224...71,903,858
JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO zinc chloride results in decreased expression of PEG3 mRNA CTD PMID:16870260 NCBI chr 7:6,703,892...6,730,462
Ensembl chr 7:6,703,892...6,730,431
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB3 mRNA] CTD PMID:22202117 NCBI chr 2:11,471,430...11,554,071
Ensembl chr 2:11,471,433...11,554,077
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB4 mRNA] CTD PMID:22202117 NCBI chr 9:108,988,272...109,032,236
Ensembl chr 9:108,991,778...109,032,228
JBrowse link
G Pgf placental growth factor increases expression ISO zinc chloride results in increased expression of PGF mRNA CTD PMID:16870260 NCBI chr12:85,166,637...85,177,785
Ensembl chr12:85,166,635...85,177,790
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PGK1 mRNA] CTD PMID:22202117 NCBI chr  X:106,187,100...106,203,699
Ensembl chr  X:106,187,100...106,203,699
JBrowse link
G Pgm1 phosphoglucomutase 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PGM1 mRNA] CTD PMID:22202117 NCBI chr 4:99,929,451...99,987,294
Ensembl chr 4:99,929,414...99,987,294
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression EXP zinc chloride results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:157,162,075...157,415,286
Ensembl chr  X:157,162,075...157,415,312
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma multiple interactions EXP PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAP3K1 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 NCBI chr12:32,173,397...32,208,677
Ensembl chr12:32,173,473...32,208,659
JBrowse link
G Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 increases expression ISO zinc chloride results in increased expression of PIK3R4 mRNA CTD PMID:16870260 NCBI chr 9:105,642,995...105,687,655
Ensembl chr 9:105,642,978...105,687,657
JBrowse link
G Pik3r5 phosphoinositide-3-kinase regulatory subunit 5 increases expression EXP zinc chloride results in increased expression of PIK3R5 mRNA CTD PMID:19000923 NCBI chr11:68,432,125...68,497,849
Ensembl chr11:68,432,121...68,497,849
JBrowse link
G Pmp22 peripheral myelin protein 22 increases expression ISO zinc chloride results in increased expression of PMP22 mRNA CTD PMID:18947441 NCBI chr11:63,128,982...63,159,547
Ensembl chr11:63,128,982...63,159,547
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
affects localization
ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]; 1,3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of PRKCA protein]; Glucose promotes the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]; Vanadates promotes the reaction [zinc chloride affects the localization of PRKCA protein]; zinc chloride affects the localization of and results in increased activity of PRKCA protein CTD PMID:20800666 PMID:21575692 NCBI chr11:107,933,387...108,343,888
Ensembl chr11:107,933,387...108,343,928
JBrowse link
G Prl2c3 prolactin family 2, subfamily c, member 3 increases expression EXP zinc chloride results in increased expression of PRL2C3 mRNA CTD PMID:19000923 NCBI chr13:12,790,816...12,800,093
Ensembl chr13:12,790,816...12,800,079
JBrowse link
G Prl8a2 prolactin family 8, subfamily a, member 2 multiple interactions EXP zinc chloride affects the reaction [Cadmium Chloride results in decreased expression of PRL8A2 mRNA] CTD PMID:16842966 NCBI chr13:27,345,673...27,354,216
Ensembl chr13:27,345,673...27,354,216
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions EXP [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of PTH1R mRNA CTD PMID:19913120 NCBI chr 9:110,722,085...110,747,145
Ensembl chr 9:110,722,085...110,747,145
JBrowse link
G Rab20 RAB20, member RAS oncogene family multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RAB20 mRNA] CTD PMID:22202117 NCBI chr 8:11,453,390...11,478,640
Ensembl chr 8:11,453,518...11,478,710
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions EXP RAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rad21 RAD21 cohesin complex component increases expression EXP zinc chloride results in increased expression of RAD21 mRNA CTD PMID:19000923 NCBI chr15:51,962,604...51,993,538
Ensembl chr15:51,962,240...51,991,747
JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression EXP zinc chloride results in increased expression of RAD51AP1 mRNA CTD PMID:19000923 NCBI chr 6:126,923,415...126,939,621
Ensembl chr 6:126,923,050...126,939,587
JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 multiple interactions
increases phosphorylation
ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein] CTD PMID:21575692 NCBI chr 6:115,618,569...115,676,635
Ensembl chr 6:115,618,067...115,676,635
JBrowse link
G Rangap1 RAN GTPase activating protein 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RANGAP1 mRNA] CTD PMID:22202117 NCBI chr15:81,704,248...81,730,798
Ensembl chr15:81,704,248...81,745,530
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RBPJ mRNA] CTD PMID:22202117 NCBI chr 5:53,555,779...53,657,445
Ensembl chr 5:53,466,152...53,657,362
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs multiple interactions ISO zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein] CTD PMID:21573219 NCBI chr 4:43,875,521...43,944,806
Ensembl chr 4:43,875,530...43,944,806
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases phosphorylation
ISO RELA protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of IL6 protein]
zinc chloride results in increased phosphorylation of RELA protein
CTD PMID:27427241 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rif1 replication timing regulatory factor 1 increases expression EXP zinc chloride results in increased expression of RIF1 mRNA CTD PMID:19000923 NCBI chr 2:52,072,815...52,126,769
Ensembl chr 2:52,072,832...52,122,383
JBrowse link
G Riok3 RIO kinase 3 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RIOK3 mRNA] CTD PMID:22202117 NCBI chr18:12,126,091...12,157,367
Ensembl chr18:12,128,741...12,157,387
JBrowse link
G Rora RAR-related orphan receptor alpha multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RORA mRNA] CTD PMID:22202117 NCBI chr 9:68,653,404...69,388,246
Ensembl chr 9:68,653,786...69,388,246
JBrowse link
G Rpl11 ribosomal protein L11 decreases expression ISO zinc chloride results in decreased expression of RPL11 mRNA CTD PMID:18947441 NCBI chr 4:136,049,354...136,053,393
Ensembl chr 4:136,028,265...136,053,428
JBrowse link
G Rrp15 ribosomal RNA processing 15 homolog multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRP15 mRNA] CTD PMID:22202117 NCBI chr 1:186,721,086...186,749,358
Ensembl chr 1:186,720,978...186,749,358
JBrowse link
G Rrs1 ribosome biogenesis regulator 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRS1 mRNA] CTD PMID:22202117 NCBI chr 1:9,545,408...9,547,455
Ensembl chr 1:9,545,408...9,547,455
JBrowse link
G Runx2 runt related transcription factor 2 multiple interactions EXP [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of RUNX2 protein; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 protein CTD PMID:19913120 NCBI chr17:44,495,987...44,814,797
Ensembl chr17:44,495,987...44,814,797
JBrowse link
G Ruvbl1 RuvB-like protein 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RUVBL1 mRNA] CTD PMID:22202117 NCBI chr 6:88,465,409...88,497,566
Ensembl chr 6:88,465,409...88,497,572
JBrowse link
G Sall1 spalt like transcription factor 1 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of SALL1 mRNA CTD PMID:31588059 NCBI chr 8:89,027,242...89,044,162
Ensembl chr 8:89,027,235...89,044,162
JBrowse link
G Sap30 sin3 associated polypeptide multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SAP30 mRNA] CTD PMID:22202117 NCBI chr 8:57,482,702...57,487,860
Ensembl chr 8:57,482,707...57,487,860
JBrowse link
G Sbno1 strawberry notch 1 increases expression ISO zinc chloride results in increased expression of SBNO1 mRNA CTD PMID:16870260 NCBI chr 5:124,368,702...124,426,007
Ensembl chr 5:124,368,702...124,426,001
JBrowse link
G Scara3 scavenger receptor class A, member 3 decreases expression ISO zinc chloride results in decreased expression of SCARA3 mRNA CTD PMID:16870260 NCBI chr14:65,919,394...65,953,978
Ensembl chr14:65,919,394...65,953,935
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression EXP zinc chloride results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr 5:125,277,087...125,341,094
Ensembl chr 5:125,277,087...125,341,094
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SCD mRNA] CTD PMID:22202117 NCBI chr19:44,293,676...44,306,864
Ensembl chr19:44,293,674...44,306,864
JBrowse link
G Selplg selectin, platelet (p-selectin) ligand increases expression ISO zinc chloride results in increased expression of SELPLG mRNA CTD PMID:21540303 NCBI chr 5:113,817,798...113,832,528
Ensembl chr 5:113,818,536...113,832,644
JBrowse link
G Sertad2 SERTA domain containing 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SERTAD2 mRNA] CTD PMID:22202117 NCBI chr11:20,543,166...20,653,023
Ensembl chr11:20,543,253...20,653,021
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 multiple interactions
increases expression
ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK2 protein] CTD PMID:25007851 NCBI chr 7:143,978,077...144,426,043
Ensembl chr 7:144,001,928...144,424,494
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions
increases expression
ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK3 protein] CTD PMID:25007851 NCBI chr15:89,493,013...89,560,261
Ensembl chr15:89,499,623...89,560,261
JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 increases transport ISO SLC11A2 protein results in increased transport of zinc chloride CTD PMID:22736759 NCBI chr15:100,387,898...100,424,209
Ensembl chr15:100,387,898...100,425,072
JBrowse link
G Slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SLC16A3 mRNA] CTD PMID:22202117 NCBI chr11:120,948,484...120,959,000
Ensembl chr11:120,948,480...120,960,868
JBrowse link
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 multiple interactions EXP [Kainic Acid co-treated with zinc chloride] results in decreased expression of SLC1A2 protein CTD PMID:19061913 NCBI chr 2:102,658,239...102,790,784
Ensembl chr 2:102,658,659...102,790,784
JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 decreases expression ISO zinc chloride results in decreased expression of SLC1A5 mRNA CTD PMID:18947441 NCBI chr 7:16,781,334...16,798,274
Ensembl chr 7:16,781,340...16,798,274
JBrowse link
G Slc25a15 solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of SLC25A15 mRNA] CTD PMID:22202117 NCBI chr 8:22,375,550...22,398,621
Ensembl chr 8:22,375,551...22,398,597
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions
increases expression
ISO
EXP
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SLC2A1 mRNA]
zinc chloride results in increased expression of SLC2A1 mRNA
CTD PMID:19000923 PMID:22202117 NCBI chr 4:119,108,745...119,137,330
Ensembl chr 4:119,108,711...119,137,983
JBrowse link
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 multiple interactions
increases expression
ISO epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of SLC30A1 mRNA]; zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in decreased expression of SLC30A1 mRNA]
zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A1 mRNA]; zinc chloride promotes the reaction [Glucose results in increased expression of SLC30A1 mRNA]
CTD PMID:18947441 PMID:20392624 PMID:20471814 PMID:23056475 PMID:25653005 More... NCBI chr 1:191,906,697...191,913,248
Ensembl chr 1:191,906,767...191,913,247
JBrowse link
G Slc30a2 solute carrier family 30 (zinc transporter), member 2 increases expression
multiple interactions
ISO zinc chloride results in increased expression of SLC30A2 mRNA
zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A2 mRNA]
CTD PMID:20392624 PMID:25653005 NCBI chr 4:134,343,046...134,354,484
Ensembl chr 4:134,343,181...134,354,484
JBrowse link
G Slc30a4 solute carrier family 30 (zinc transporter), member 4 multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A4 mRNA] CTD PMID:25653005 NCBI chr 2:122,681,233...122,702,663
Ensembl chr 2:122,681,233...122,702,663
JBrowse link
G Slc30a5 solute carrier family 30 (zinc transporter), member 5 decreases expression
multiple interactions
ISO zinc chloride results in decreased expression of SLC30A5 mRNA
Dactinomycin inhibits the reaction [zinc chloride results in decreased expression of SLC30A5 mRNA]
CTD PMID:17234632 PMID:20392624 NCBI chr13:100,802,645...100,833,480
Ensembl chr13:100,802,648...100,833,427
JBrowse link
G Slc30a7 solute carrier family 30 (zinc transporter), member 7 increases expression
decreases expression
ISO zinc chloride results in increased expression of SLC30A7 mRNA
zinc chloride results in decreased expression of SLC30A7 mRNA
CTD PMID:20392624 NCBI chr 3:115,938,973...116,007,414
Ensembl chr 3:115,938,973...116,007,406
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G Slc31a2 solute carrier family 31, member 2 increases expression
decreases expression
ISO zinc chloride results in increased expression of SLC31A2 mRNA
zinc chloride results in decreased expression of SLC31A2 mRNA
CTD PMID:18947441 NCBI chr 4:62,280,393...62,298,412
Ensembl chr 4:62,262,562...62,298,411
JBrowse link
G Slc39a1 solute carrier family 39 (zinc transporter), member 1 multiple interactions ISO zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A1 mRNA] CTD PMID:20471814 NCBI chr 3:90,248,190...90,253,613
Ensembl chr 3:90,248,172...90,253,612
JBrowse link
G Slc39a2 solute carrier family 39 (zinc transporter), member 2 multiple interactions
increases expression
ISO [SLC39A2 protein co-treated with zinc chloride] results in increased abundance of Glutathione; zinc chloride promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]; zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLC mRNA]; zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA]
zinc chloride results in increased expression of SLC39A2 mRNA
CTD PMID:18385089 NCBI chr14:51,893,082...51,896,745
Ensembl chr14:51,892,889...51,896,745
JBrowse link
G Slc39a3 solute carrier family 39 (zinc transporter), member 3 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A3 mRNA] CTD PMID:25653005 NCBI chr10:81,028,540...81,037,338
Ensembl chr10:81,028,538...81,037,426
JBrowse link
G Slc39a4 solute carrier family 39 (zinc transporter), member 4 multiple interactions
decreases expression
ISO zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A4 mRNA]
zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A4 mRNA]
zinc chloride results in decreased expression of SLC39A4 mRNA
CTD PMID:20471814 PMID:25653005 NCBI chr15:76,612,383...76,618,506
Ensembl chr15:76,612,383...76,617,384
JBrowse link
G Slc39a8 solute carrier family 39 (metal ion transporter), member 8 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A8 mRNA] CTD PMID:25653005 NCBI chr 3:135,816,882...135,888,572
Ensembl chr 3:135,825,279...135,888,572
JBrowse link
G Slc48a1 solute carrier family 48 (heme transporter), member 1 increases expression ISO zinc chloride results in increased expression of SLC48A1 mRNA CTD PMID:16870260 NCBI chr15:97,784,365...97,792,692
Ensembl chr15:97,778,520...97,792,692
JBrowse link
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A1 mRNA] CTD PMID:20060848 NCBI chr 5:33,104,219...33,162,699
Ensembl chr 5:33,104,219...33,162,870
JBrowse link
G Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP110 protein binds to and affects the expression of SLC5A2 promoter]]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A2 mRNA] CTD PMID:20060848 NCBI chr 7:128,265,683...128,272,430
Ensembl chr 7:128,265,657...128,272,430
JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 increases expression ISO zinc chloride results in increased expression of SLC9A1 mRNA CTD PMID:18947441 NCBI chr 4:133,369,711...133,423,702
Ensembl chr 4:133,369,706...133,423,702
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of SORD protein] CTD PMID:18972399 NCBI chr 2:122,234,839...122,265,337
Ensembl chr 2:122,234,749...122,265,340
JBrowse link
G Sp1 trans-acting transcription factor 1 multiple interactions
increases activity
EXP
ISO
zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]]
zinc chloride results in increased activity of SP1 protein
CTD PMID:9330853 PMID:20060848 NCBI chr15:102,406,316...102,436,404
Ensembl chr15:102,406,143...102,436,404
JBrowse link
G Sp110 Sp110 nuclear body protein multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP110 protein binds to and affects the expression of SLC5A2 promoter]] CTD PMID:20060848 NCBI chr 1:85,570,735...85,610,850
Ensembl chr 1:85,576,899...85,598,817
JBrowse link
G Spag4 sperm associated antigen 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SPAG4 mRNA] CTD PMID:22202117 NCBI chr 2:156,065,188...156,069,501
Ensembl chr 2:156,065,175...156,070,617
JBrowse link
G Spice1 spindle and centriole associated protein 1 decreases expression ISO zinc chloride results in decreased expression of SPICE1 mRNA CTD PMID:16870260 NCBI chr16:44,347,399...44,388,492
Ensembl chr16:44,347,121...44,388,497
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression ISO zinc chloride results in decreased expression of SPINK1 mRNA CTD PMID:18947441 NCBI chr18:43,728,069...43,737,237
Ensembl chr18:43,728,082...43,737,557
JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SPOCK1 mRNA] CTD PMID:22202117 NCBI chr13:57,421,195...57,908,332
Ensembl chr13:57,421,195...57,908,332
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression
multiple interactions
ISO
EXP
zinc chloride results in decreased expression of SPP1 mRNA
[zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of SPP1 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SPP1 mRNA; zinc chloride promotes the reaction [Calcitriol results in increased activity of SPP1 promoter]
CTD PMID:10777672 PMID:19428942 PMID:19913120 NCBI chr 5:104,435,111...104,441,053
Ensembl chr 5:104,435,118...104,441,050
JBrowse link
G Src Rous sarcoma oncogene multiple interactions
increases phosphorylation
ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]; Vanadates promotes the reaction [zinc chloride results in increased phosphorylation of SRC protein] CTD PMID:12211081 PMID:21575692 NCBI chr 2:157,423,906...157,471,838
Ensembl chr 2:157,418,444...157,471,862
JBrowse link
G Srm spermidine synthase multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of SRM mRNA] CTD PMID:22202117 NCBI chr 4:148,591,513...148,594,619
Ensembl chr 4:148,591,503...148,594,993
JBrowse link
G Stbd1 starch binding domain 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of STBD1 mRNA] CTD PMID:22202117 NCBI chr 5:92,603,051...92,606,579
Ensembl chr 5:92,603,041...92,606,579
JBrowse link
G Stmn1 stathmin 1 increases expression EXP zinc chloride results in increased expression of STMN1 mRNA CTD PMID:19000923 NCBI chr 4:134,468,320...134,473,843
Ensembl chr 4:134,468,320...134,473,843
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in decreased activity of TERT protein CTD PMID:16624386 NCBI chr13:73,626,911...73,649,843
Ensembl chr13:73,626,911...73,649,843
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO zinc chloride results in increased expression of TFPI2 mRNA CTD PMID:16870260 NCBI chr 6:3,962,589...3,988,978
Ensembl chr 6:3,962,595...3,988,919
JBrowse link
G Tfrc transferrin receptor increases expression EXP zinc chloride results in increased expression of TFRC mRNA CTD PMID:19000923 NCBI chr16:32,608,896...32,632,794
Ensembl chr16:32,608,920...32,632,794
JBrowse link
G Tmem45a transmembrane protein 45a multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of TMEM45A mRNA] CTD PMID:22202117 NCBI chr16:56,805,161...56,886,433
Ensembl chr16:56,805,161...56,886,166
JBrowse link
G Tnf tumor necrosis factor increases expression ISO
EXP
zinc chloride results in increased expression of TNF mRNA CTD PMID:19428942 PMID:21540303 PMID:24284788 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of TNFRSF11B protein] CTD PMID:23726800 NCBI chr15:54,250,619...54,278,484
Ensembl chr15:54,250,619...54,278,484
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of TNFSF11 protein] CTD PMID:23726800 NCBI chr14:78,277,446...78,308,043
Ensembl chr14:78,277,445...78,308,043
JBrowse link
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of TNFSF14 mRNA CTD PMID:31588059 NCBI chr17:57,189,474...57,194,181
Ensembl chr17:57,189,492...57,194,177
JBrowse link
G Tra2a transformer 2 alpha decreases expression ISO zinc chloride results in decreased expression of TRA2A mRNA CTD PMID:16870260 NCBI chr 6:49,243,921...49,264,248
Ensembl chr 6:49,243,924...49,264,033
JBrowse link
G Trf transferrin multiple interactions
increases expression
ISO zinc chloride inhibits the reaction [TF protein results in increased uptake of Iron]
zinc chloride results in increased expression of TF mRNA
CTD PMID:11335103 PMID:18947441 NCBI chr 9:103,208,876...103,230,286
Ensembl chr 9:103,204,001...103,230,444
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]] CTD PMID:19714248 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [zinc chloride results in increased abundance of Zinc] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:140,539,528...140,600,522
Ensembl chr  X:140,539,528...140,600,659
JBrowse link
G Ttr transthyretin multiple interactions EXP [zinc chloride results in increased abundance of Zinc] which results in increased expression of TTR mRNA CTD PMID:31588059 NCBI chr18:20,664,209...20,674,326
Ensembl chr18:20,665,280...20,674,321
JBrowse link
G Tuba1b tubulin, alpha 1B increases expression ISO zinc chloride results in increased expression of TUBA1B mRNA CTD PMID:18947441 NCBI chr15:98,931,429...98,934,390
Ensembl chr15:98,931,425...98,934,565
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO zinc chloride promotes the reaction [Dimethyldithiocarbamate results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; zinc chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:20,658,302...20,683,179
Ensembl chr  X:20,658,326...20,683,179
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 increases expression ISO zinc chloride results in increased expression of UBE2E2 mRNA CTD PMID:18947441 NCBI chr14:18,573,563...18,894,284
Ensembl chr14:18,573,575...18,894,267
JBrowse link
G Unc5b unc-5 netrin receptor B increases expression ISO zinc chloride results in increased expression of UNC5B mRNA CTD PMID:18947441 NCBI chr10:60,762,594...60,831,581
Ensembl chr10:60,762,593...60,831,581
JBrowse link
G Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) increases expression ISO zinc chloride results in increased expression of USE1 mRNA CTD PMID:16870260 NCBI chr 8:71,366,848...71,369,732
Ensembl chr 8:71,366,848...71,369,732
JBrowse link
G Utrn utrophin affects binding ISO zinc chloride binds to UTRN protein CTD PMID:17009962