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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 5.3.* (intramolecular oxidoreductase) inhibitor
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Accession:CHEBI:76694 term browser browse the term
Definition:An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*).
Synonyms:related_synonym: intramolecular oxidoreductase (EC 5.3.*) inhibitors;   intramolecular oxidoreductase inhibitor;   intramolecular oxidoreductase inhibitors


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amorolfine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 multiple interactions EXP amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA] CTD PMID:23688403 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions EXP amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA]; amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 protein] CTD PMID:24471457 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA] CTD PMID:23688403 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G IL4 interleukin 4 multiple interactions EXP 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; amorolfine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone] CTD PMID:23688403 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 decreases activity EXP amorolfine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein] CTD PMID:23688403 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions EXP amorolfine inhibits the reaction [Biological Products results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:24471457 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TSLP thymic stromal lymphopoietin multiple interactions EXP 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein] CTD PMID:23688403 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
copper(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase decreases expression EXP cupric chloride results in decreased expression of AASDHPPT mRNA CTD PMID:17211630 NCBI chr11:106,077,662...106,098,695
Ensembl chr11:106,075,501...106,098,699 		JBrowse link
G ABCF3 ATP binding cassette subfamily F member 3 increases expression EXP cupric chloride results in increased expression of ABCF3 mRNA CTD PMID:17211630 NCBI chr 3:184,186,199...184,194,005
Ensembl chr 3:184,186,095...184,194,012 		JBrowse link
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression EXP cupric chloride results in increased expression of ABHD4 mRNA CTD PMID:17211630 NCBI chr14:22,598,300...22,612,963
Ensembl chr14:22,598,290...22,612,963 		JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 decreases expression EXP cupric chloride results in decreased expression of ACAT2 mRNA CTD PMID:34921933 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions
decreases activity		 ISO
EXP		 cupric chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ACHE protein]
cupric chloride results in decreased activity of ACHE protein
Carnosine inhibits the reaction [cupric chloride results in decreased activity of ACHE protein]		 CTD PMID:24799335 PMID:32745495 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACO1 aconitase 1 decreases expression ISO cupric chloride results in decreased expression of ACO1 protein CTD PMID:29617964 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769 		JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 decreases expression EXP cupric chloride results in decreased expression of ACSS2 mRNA CTD PMID:34921933 NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962 		JBrowse link
G ACTB actin beta increases expression ISO cupric chloride results in increased expression of ACTB protein CTD PMID:29617964 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G ADRM1 ADRM1 26S proteasome ubiquitin receptor increases expression EXP cupric chloride results in increased expression of ADRM1 mRNA CTD PMID:17211630 NCBI chr20:62,302,896...62,308,862
Ensembl chr20:62,302,093...62,308,862 		JBrowse link
G AHSG alpha 2-HS glycoprotein decreases expression EXP cupric chloride results in decreased expression of AHSG mRNA CTD PMID:17211630 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 increases expression ISO cupric chloride results in increased expression of AKR1A1 protein CTD PMID:29617964 NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049 		JBrowse link
G ALB albumin multiple interactions EXP ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein] CTD PMID:11820775 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 increases expression ISO cupric chloride results in increased expression of ALDH1L1 mRNA CTD PMID:17211630 NCBI chr 3:126,103,570...126,197,945
Ensembl chr 3:126,103,562...126,197,994 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A increases expression ISO cupric chloride results in increased expression of ALDOA protein CTD PMID:29617964 NCBI chr16:30,053,151...30,070,414
Ensembl chr16:30,053,090...30,070,420
Ensembl chr16:30,053,090...30,070,420
Ensembl chr16:30,053,090...30,070,420 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A increases expression EXP cupric chloride results in increased expression of ALDOA mRNA CTD PMID:17211630 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G ALDOC aldolase, fructose-bisphosphate C decreases expression ISO cupric chloride results in decreased expression of ALDOC protein CTD PMID:29617964 NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948 		JBrowse link
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase decreases activity EXP cupric chloride results in decreased activity of ALKBH2 protein CTD PMID:28926697 NCBI chr12:109,088,189...109,093,472
Ensembl chr12:109,088,188...109,093,631 		JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase decreases activity EXP cupric chloride results in decreased activity of ALKBH3 protein CTD PMID:28926697 NCBI chr11:43,880,831...43,920,274
Ensembl chr11:43,880,811...43,920,274 		JBrowse link
G ANKRD1 ankyrin repeat domain 1 increases expression EXP cupric chloride results in increased expression of ANKRD1 mRNA CTD PMID:17211630 NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane decreases expression EXP cupric chloride results in decreased expression of ANPEP mRNA CTD PMID:17211630 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G APOM apolipoprotein M increases expression ISO cupric chloride results in increased expression of APOM mRNA CTD PMID:17211630 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210 		JBrowse link
G APP amyloid beta precursor protein increases expression
multiple interactions		 ISO cupric chloride results in increased expression of APP mRNA; cupric chloride results in increased expression of APP protein
cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form; PP242 inhibits the reaction [cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form]		 CTD PMID:22542740 PMID:32512069 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G AR androgen receptor multiple interactions EXP [Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein CTD PMID:19789329 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ATF2 activating transcription factor 2 multiple interactions ISO [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein] CTD PMID:30768131 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G ATF4 activating transcription factor 4 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] CTD PMID:20920558 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G ATM ATM serine/threonine kinase multiple interactions EXP cupric chloride results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,223,044...108,369,102 		JBrowse link
G ATOX1 antioxidant 1 copper chaperone multiple interactions EXP [cupric chloride results in increased abundance of Copper] which results in increased expression of ATOX1 mRNA; ATOX1 protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper] CTD PMID:32278528 NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532 		JBrowse link
G ATP7A ATPase copper transporting alpha increases transport
multiple interactions
affects localization
decreases glutathionylation
increases expression		 EXP
ISO		 ATP7A protein results in increased transport of cupric chloride
ATP7A protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7A protein results in decreased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]]; cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]
Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
cupric chloride results in decreased glutathionylation of ATP7A protein
cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein]; cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]		 CTD PMID:11092760 PMID:16317117 PMID:17009961 PMID:20566629 PMID:21242307 More... NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G ATP7B ATPase copper transporting beta decreases response to substance
affects localization
multiple interactions		 EXP
ISO		 ATP7B protein results in decreased susceptibility to cupric chloride
cupric chloride affects the localization of ATP7B protein
ATP7B protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7B protein results in increased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]		 CTD PMID:10728692 PMID:16799059 PMID:21242307 PMID:24343273 PMID:32278528 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G BACE1 beta-secretase 1 increases expression ISO cupric chloride results in increased expression of BACE1 mRNA; cupric chloride results in increased expression of BACE1 protein CTD PMID:22542740 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259 		JBrowse link
G BAG3 BAG cochaperone 3 increases expression EXP cupric chloride results in increased expression of BAG3 mRNA CTD PMID:17211630 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO
EXP		 cupric chloride results in increased expression of BAX protein
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of BAX protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]		 CTD PMID:21035945 PMID:22239859 PMID:23313662 PMID:24170445 PMID:29803612 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 ISO
EXP		 [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein]
[Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein
cupric chloride results in decreased expression of BCL2 protein		 CTD PMID:20920558 PMID:21911303 PMID:23313662 PMID:24170445 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression ISO cupric chloride results in decreased expression of BCL2L1 protein CTD PMID:23313662 PMID:24170445 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BID BH3 interacting domain death agonist increases expression EXP cupric chloride results in increased expression of BID mRNA CTD PMID:17211630 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BLVRB biliverdin reductase B increases expression EXP cupric chloride results in increased expression of BLVRB mRNA CTD PMID:17211630 NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764 		JBrowse link
G C1QTNF4 C1q and TNF related 4 increases expression ISO cupric chloride results in increased expression of C1QTNF4 mRNA CTD PMID:17211630 NCBI chr11:47,589,667...47,595,304
Ensembl chr11:47,589,667...47,594,411 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
increases activity
decreases activity		 ISO
EXP		 [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP3 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]
cupric chloride results in increased expression of CASP3 protein
cupric chloride results in increased activity of CASP3 protein
cupric chloride results in decreased activity of CASP3 protein		 CTD PMID:11239917 PMID:18056745 PMID:20920558 PMID:21035945 PMID:22954531 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 multiple interactions ISO
EXP		 [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein]
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]		 CTD PMID:20920558 PMID:21035945 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 increases expression ISO cupric chloride results in increased expression of CASP8 protein CTD PMID:23313662 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression		 ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein]
cupric chloride results in increased expression of CASP9 protein		 CTD PMID:20920558 PMID:23313662 PMID:24170445 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions
decreases activity		 EXP Carnosine inhibits the reaction [cupric chloride results in decreased activity of CAT protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] CTD PMID:29803612 PMID:32745495 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCN1 cellular communication network factor 1 increases expression EXP cupric chloride results in increased expression of CCN1 mRNA CTD PMID:17211630 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CCS copper chaperone for superoxide dismutase multiple interactions EXP cupric chloride results in increased degradation of and results in decreased expression of CCS protein CTD PMID:16531609 NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019 		JBrowse link
G CD63 CD63 molecule decreases expression EXP cupric chloride results in decreased expression of CD63 mRNA CTD PMID:17211630 NCBI chr12:55,725,323...55,729,673
Ensembl chr12:55,725,323...55,729,707 		JBrowse link
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme affects expression EXP cupric chloride affects the expression of CDC34 mRNA CTD PMID:17211630 NCBI chr19:531,760...542,087
Ensembl chr19:531,760...542,092 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A affects expression EXP cupric chloride affects the expression of CDKN1A mRNA CTD PMID:17211630 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B affects expression ISO cupric chloride affects the expression of CDKN1B protein CTD PMID:23313662 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 increases expression EXP cupric chloride results in increased expression of CHORDC1 mRNA CTD PMID:17211630 NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077 		JBrowse link
G CKMT2 creatine kinase, mitochondrial 2 decreases expression ISO cupric chloride results in decreased expression of CKMT2 protein CTD PMID:29617964 NCBI chr 5:81,233,322...81,266,398
Ensembl chr 5:81,233,320...81,266,398 		JBrowse link
G CKS2 CDC28 protein kinase regulatory subunit 2 increases expression EXP cupric chloride results in increased expression of CKS2 mRNA CTD PMID:17211630 NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,195...89,316,703 		JBrowse link
G CLCN6 chloride voltage-gated channel 6 increases expression
decreases expression		 EXP cupric chloride results in increased expression of CLCN6 mRNA
cupric chloride results in decreased expression of CLCN6 mRNA		 CTD PMID:17211630 PMID:34921933 NCBI chr 1:11,806,191...11,843,130
Ensembl chr 1:11,806,096...11,848,079 		JBrowse link
G CLCN7 chloride voltage-gated channel 7 affects expression EXP cupric chloride affects the expression of CLCN7 mRNA CTD PMID:17211630 NCBI chr16:1,444,935...1,475,028
Ensembl chr16:1,444,934...1,475,077 		JBrowse link
G CLDND1 claudin domain containing 1 increases expression EXP cupric chloride results in increased expression of CLDND1 mRNA CTD PMID:17211630 NCBI chr 3:98,515,483...98,522,902
Ensembl chr 3:98,497,912...98,523,066 		JBrowse link
G CLU clusterin multiple interactions
increases expression		 EXP
ISO		 cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
cupric chloride results in increased expression of CLU mRNA		 CTD PMID:17211630 PMID:21242307 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G COMMD1 copper metabolism domain containing 1 decreases response to substance
multiple interactions
decreases expression		 EXP
ISO		 COMMD1 protein results in decreased susceptibility to cupric chloride
cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]
[COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein
cupric chloride results in decreased expression of COMMD1 mRNA; cupric chloride results in decreased expression of COMMD1 protein		 CTD PMID:17211630 PMID:24691167 PMID:25007851 NCBI chr 2:61,888,391...62,136,058
Ensembl chr 2:61,888,724...62,147,247 		JBrowse link
G COMMD10 COMM domain containing 10 decreases expression EXP cupric chloride results in decreased expression of COMMD10 mRNA CTD PMID:17211630 NCBI chr 5:116,085,025...116,293,287
Ensembl chr 5:116,085,016...116,412,762 		JBrowse link
G COMMD2 COMM domain containing 2 decreases expression EXP cupric chloride results in decreased expression of COMMD2 mRNA CTD PMID:17211630 NCBI chr 3:149,738,472...149,752,489
Ensembl chr 3:149,738,472...149,752,495 		JBrowse link
G COMMD3 COMM domain containing 3 decreases expression EXP cupric chloride results in decreased expression of COMMD3 mRNA CTD PMID:17211630 NCBI chr10:22,316,388...22,320,306
Ensembl chr10:22,316,386...22,320,306 		JBrowse link
G COMMD4 COMM domain containing 4 decreases expression EXP cupric chloride results in decreased expression of COMMD4 mRNA CTD PMID:17211630 NCBI chr15:75,336,063...75,343,227
Ensembl chr15:75,336,020...75,343,224 		JBrowse link
G COMMD5 COMM domain containing 5 decreases expression EXP cupric chloride results in decreased expression of COMMD5 mRNA CTD PMID:17211630 NCBI chr 8:144,837,978...144,853,556
Ensembl chr 8:144,841,042...144,853,736 		JBrowse link
G COMMD6 COMM domain containing 6 decreases expression EXP cupric chloride results in decreased expression of COMMD6 mRNA CTD PMID:17211630 NCBI chr13:75,525,214...75,549,439
Ensembl chr13:75,525,214...75,549,439 		JBrowse link
G COMMD7 COMM domain containing 7 decreases expression EXP cupric chloride results in decreased expression of COMMD7 mRNA CTD PMID:17211630 NCBI chr20:32,702,699...32,743,467
Ensembl chr20:32,702,699...32,743,467 		JBrowse link
G COMMD8 COMM domain containing 8 decreases expression EXP cupric chloride results in decreased expression of COMMD8 mRNA CTD PMID:17211630 NCBI chr 4:47,450,787...47,463,702
Ensembl chr 4:47,450,787...47,463,702 		JBrowse link
G COX16 cytochrome c oxidase assembly factor COX16 affects expression EXP cupric chloride affects the expression of COX16 mRNA CTD PMID:17211630 NCBI chr14:70,325,081...70,359,683
Ensembl chr14:70,325,081...70,416,984 		JBrowse link
G COX5B cytochrome c oxidase subunit 5B decreases expression ISO cupric chloride results in decreased expression of COX5B protein CTD PMID:29617964 NCBI chr 2:97,646,062...97,648,383
Ensembl chr 2:97,646,062...97,648,383 		JBrowse link
G COX6A1 cytochrome c oxidase subunit 6A1 increases expression ISO cupric chloride results in increased expression of COX6A1 protein CTD PMID:29617964 NCBI chr12:120,438,113...120,440,730
Ensembl chr12:120,438,090...120,440,737 		JBrowse link
G CP ceruloplasmin increases expression EXP cupric chloride results in increased expression of CP mRNA CTD PMID:15741220 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CPLX2 complexin 2 decreases expression ISO cupric chloride results in decreased expression of CPLX2 protein CTD PMID:29617964 NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021 		JBrowse link
G CRYAB crystallin alpha B increases expression EXP cupric chloride results in increased expression of CRYAB mRNA CTD PMID:17211630 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CSNK1G1 casein kinase 1 gamma 1 decreases expression EXP cupric chloride results in decreased expression of CSNK1G1 mRNA CTD PMID:34921933 NCBI chr15:64,165,525...64,356,173
Ensembl chr15:64,165,525...64,356,173 		JBrowse link
G CSTB cystatin B affects binding EXP CSTB protein binds to cupric chloride CTD PMID:16939620 NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330 		JBrowse link
G CTSB cathepsin B multiple interactions
decreases expression		 ISO PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB protein]
cupric chloride results in decreased expression of CTSB mRNA; cupric chloride results in decreased expression of CTSB protein		 CTD PMID:32512069 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSD cathepsin D decreases expression
multiple interactions		 ISO cupric chloride results in decreased expression of CTSD mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSD mRNA]		 CTD PMID:32512069 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases secretion
increases expression		 EXP cupric chloride results in increased secretion of CXCL8 protein
cupric chloride results in increased expression of CXCL8 mRNA; cupric chloride results in increased expression of CXCL8 protein		 CTD PMID:12865660 PMID:17211630 PMID:29355601 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYBC1 cytochrome b-245 chaperone 1 increases expression EXP cupric chloride results in increased expression of CYBC1 mRNA CTD PMID:34921933 NCBI chr17:82,442,586...82,450,752
Ensembl chr17:82,440,912...82,450,829 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein CTD PMID:20920558 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 decreases expression EXP cupric chloride results in decreased expression of CYFIP2 mRNA CTD PMID:17211630 NCBI chr 5:157,266,123...157,395,594
Ensembl chr 5:157,266,079...157,395,595 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases stability
multiple interactions		 ISO cupric chloride results in increased stability of CYP1A1 mRNA; cupric chloride results in increased stability of CYP1A1 protein
[1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]		 CTD PMID:19896525 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 increases expression ISO cupric chloride results in increased expression of CYP27A1 mRNA CTD PMID:17211630 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions EXP [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of N'-nitrosonornicotine CTD PMID:32672941 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 increases expression ISO cupric chloride results in increased expression of CYP2C38 mRNA CTD PMID:17211630 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 decreases expression EXP cupric chloride results in decreased expression of CYP51A1 mRNA CTD PMID:34921933 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression		 ISO
EXP		 pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA]
cupric chloride results in increased expression of DDIT3 mRNA		 CTD PMID:17211630 PMID:20920558 NCBI chr12:57,516,588...57,521,698
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DERL3 derlin 3 decreases expression EXP cupric chloride results in decreased expression of DERL3 mRNA CTD PMID:34921933 NCBI chr22:23,834,503...23,839,006
Ensembl chr22:23,834,503...23,839,128 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase decreases expression EXP cupric chloride results in decreased expression of DHCR7 mRNA CTD PMID:34921933 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 increases expression EXP cupric chloride results in increased expression of DKK1 mRNA CTD PMID:17211630 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042 		JBrowse link
G DMD dystrophin increases expression EXP cupric chloride results in increased expression of DMD mRNA CTD PMID:17211630 NCBI chr  X:31,119,222...33,339,388
Ensembl chr  X:31,097,677...33,339,609 		JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP cupric chloride results in increased expression of DNAJB1 mRNA CTD PMID:17211630 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391 		JBrowse link
G DPYSL2 dihydropyrimidinase like 2 increases expression ISO cupric chloride results in increased expression of DPYSL2 protein CTD PMID:29617964 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178 		JBrowse link
G DPYSL5 dihydropyrimidinase like 5 increases expression ISO cupric chloride results in increased expression of DPYSL5 protein CTD PMID:29617964 NCBI chr 2:26,847,995...26,950,351
Ensembl chr 2:26,847,747...26,950,351 		JBrowse link
G DUSP1 dual specificity phosphatase 1 increases expression EXP cupric chloride results in increased expression of DUSP1 mRNA CTD PMID:17211630 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G EBP EBP cholestenol delta-isomerase decreases expression EXP cupric chloride results in decreased expression of EBP mRNA CTD PMID:34921933 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G EGR1 early growth response 1 affects expression EXP cupric chloride affects the expression of EGR1 mRNA CTD PMID:17211630 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G ELAC2 elaC ribonuclease Z 2 affects expression EXP cupric chloride affects the expression of ELAC2 mRNA CTD PMID:17211630 NCBI chr17:12,991,612...13,018,027
Ensembl chr17:12,991,612...13,018,065 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 increases expression EXP cupric chloride results in increased expression of ELOVL1 mRNA CTD PMID:17211630 NCBI chr 1:43,363,401...43,368,011
Ensembl chr 1:43,363,398...43,368,074 		JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 decreases expression EXP cupric chloride results in decreased expression of ELOVL6 mRNA CTD PMID:34921933 NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199 		JBrowse link
G EML4 EMAP like 4 decreases expression EXP cupric chloride results in decreased expression of EML4 mRNA CTD PMID:17211630 NCBI chr 2:42,169,353...42,332,548
Ensembl chr 2:42,169,353...42,332,548 		JBrowse link
G ENAM enamelin affects expression EXP cupric chloride affects the expression of ENAM mRNA CTD PMID:17211630 NCBI chr 4:70,628,744...70,646,824
Ensembl chr 4:70,628,744...70,646,824 		JBrowse link
G ENDOG endonuclease G increases expression ISO cupric chloride results in increased expression of ENDOG protein CTD PMID:22239859 NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676 		JBrowse link
G ERG28 ergosterol biosynthesis 28 homolog decreases expression EXP cupric chloride results in decreased expression of ERG28 mRNA CTD PMID:34921933 NCBI chr14:75,649,791...75,660,876
Ensembl chr14:75,649,791...75,660,876 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
increases activity
affects response to substance
decreases expression		 EXP cupric chloride inhibits the reaction [Estradiol binds to ESR1 protein]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 mRNA]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 mRNA]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 protein]
cupric chloride results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to cupric chloride
cupric chloride results in decreased expression of ESR1 mRNA; cupric chloride results in decreased expression of ESR1 protein		 CTD PMID:12746304 PMID:17716812 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G F2 coagulation factor II, thrombin increases expression ISO cupric chloride results in increased expression of F2 mRNA CTD PMID:17211630 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FAM219A family with sequence similarity 219 member A increases expression EXP cupric chloride results in increased expression of FAM219A mRNA CTD PMID:17211630 NCBI chr 9:34,398,184...34,458,570
Ensembl chr 9:34,398,184...34,458,570 		JBrowse link
G FAM89B family with sequence similarity 89 member B increases expression EXP cupric chloride results in increased expression of FAM89B mRNA CTD PMID:17211630 NCBI chr11:65,572,538...65,574,190
Ensembl chr11:65,572,349...65,574,198 		JBrowse link
G FASN fatty acid synthase decreases expression EXP cupric chloride results in decreased expression of FASN mRNA CTD PMID:34921933 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 decreases expression EXP cupric chloride results in decreased expression of FDFT1 mRNA CTD PMID:34921933 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,304 		JBrowse link
G FETUB fetuin B increases expression ISO cupric chloride results in increased expression of FETUB mRNA CTD PMID:17211630 NCBI chr 3:186,635,969...186,653,141
Ensembl chr 3:186,635,969...186,653,141 		JBrowse link
G FGF1 fibroblast growth factor 1 multiple interactions EXP [amlexanox binds to FGF1 protein] inhibits the reaction [cupric chloride results in increased oxidation of FGF1 protein] CTD PMID:16300395 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 affects expression EXP cupric chloride affects the expression of FGFR1 mRNA CTD PMID:17211630 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G FHL3 four and a half LIM domains 3 increases expression EXP cupric chloride results in increased expression of FHL3 mRNA CTD PMID:17211630 NCBI chr 1:37,996,770...38,005,514
Ensembl chr 1:37,996,770...38,005,606 		JBrowse link
G FKBP4 FKBP prolyl isomerase 4 increases expression EXP cupric chloride results in increased expression of FKBP4 mRNA CTD PMID:17211630 NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423 		JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 decreases expression EXP cupric chloride results in decreased expression of FMO5 mRNA CTD PMID:17211630 NCBI chr 1:147,184,305...147,227,284
Ensembl chr 1:147,175,351...147,243,050 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP cupric chloride results in increased expression of FOS mRNA CTD PMID:17211630 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FTH1P5 ferritin heavy chain 1 pseudogene 5 increases expression EXP cupric chloride results in increased expression of FTH1P5 mRNA CTD PMID:17211630 NCBI chr 6:50,912,550...50,913,462
Ensembl chr 6:50,912,712...50,913,256 		JBrowse link
G FUBP1 far upstream element binding protein 1 increases expression ISO cupric chloride results in increased expression of FUBP1 protein CTD PMID:29617964 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 affects expression EXP cupric chloride affects the expression of FXYD2 mRNA CTD PMID:17211630 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase multiple interactions
decreases activity		 EXP Carnosine inhibits the reaction [cupric chloride results in decreased activity of G6PD protein] CTD PMID:32745495 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GABARAPL3 GABA type A receptor associated protein like 3 pseudogene increases expression EXP cupric chloride results in increased expression of GABARAPL3 mRNA CTD PMID:17211630 NCBI chr15:90,346,527...90,349,447
Ensembl chr15:90,348,844...90,349,197 		JBrowse link
G GABRE gamma-aminobutyric acid type A receptor subunit epsilon increases expression EXP cupric chloride results in increased expression of GABRE mRNA CTD PMID:17211630 NCBI chr  X:151,953,124...151,974,676
Ensembl chr  X:151,953,124...151,974,680 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP cupric chloride results in increased expression of GADD45A mRNA CTD PMID:17211630 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression EXP cupric chloride results in increased expression of GCLC mRNA CTD PMID:17211630 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP cupric chloride results in increased expression of GCLM mRNA CTD PMID:17211630 PMID:24343273 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GDI1 GDP dissociation inhibitor 1 increases expression ISO cupric chloride results in increased expression of GDI1 protein CTD PMID:29617964 NCBI chr  X:154,437,154...154,443,467
Ensembl chr  X:154,436,913...154,443,467 		JBrowse link
G GLA galactosidase alpha increases expression EXP cupric chloride results in increased expression of GLA mRNA CTD PMID:17211630 NCBI chr  X:101,397,803...101,407,925
Ensembl chr  X:101,393,273...101,408,012 		JBrowse link
G GLUD1 glutamate dehydrogenase 1 decreases expression EXP cupric chloride results in decreased expression of GLUD1 mRNA CTD PMID:17211630 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843 		JBrowse link
G GPRC5C G protein-coupled receptor class C group 5 member C decreases expression EXP cupric chloride results in decreased expression of GPRC5C mRNA CTD PMID:34921933 NCBI chr17:74,432,088...74,451,658
Ensembl chr17:74,424,851...74,451,653 		JBrowse link
G GSR glutathione-disulfide reductase decreases activity
multiple interactions		 EXP cupric chloride results in decreased activity of GSR protein
Carnosine inhibits the reaction [cupric chloride results in decreased activity of GSR protein]		 CTD PMID:32745495 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GTPBP2 GTP binding protein 2 affects expression EXP cupric chloride affects the expression of GTPBP2 mRNA CTD PMID:17211630 NCBI chr 6:43,620,494...43,631,333
Ensembl chr 6:43,605,316...43,629,264 		JBrowse link
G GTPBP6 GTP binding protein 6 (putative) increases expression EXP cupric chloride results in increased expression of GTPBP6 mRNA CTD PMID:17211630 NCBI chr  X:304,759...318,796
NCBI chr  Y:304,759...318,796
Ensembl chr  X:304,529...318,796 		JBrowse link
G GYPE glycophorin E (MNS blood group) affects expression EXP cupric chloride affects the expression of GYPE mRNA CTD PMID:17211630 NCBI chr 4:143,870,864...143,905,559
Ensembl chr 4:143,870,864...143,905,563 		JBrowse link
G H2BC21 H2B clustered histone 21 decreases expression EXP cupric chloride results in decreased expression of H2BC21 mRNA CTD PMID:34921933 NCBI chr 1:149,884,459...149,886,682
Ensembl chr 1:149,884,459...149,886,682 		JBrowse link
G HAMP hepcidin antimicrobial peptide increases expression ISO cupric chloride results in increased expression of HAMP mRNA CTD PMID:17211630 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143 		JBrowse link
G HEXA hexosaminidase subunit alpha decreases expression
multiple interactions		 ISO cupric chloride results in decreased expression of HEXA mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of HEXA mRNA]		 CTD PMID:32512069 NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,924...72,376,420 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases stability
affects localization
decreases hydroxylation		 EXP Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; cupric chloride results in decreased hydroxylation of and results in decreased degradation of HIF1A protein
cupric chloride affects the localization of HIF1A protein		 CTD PMID:15741220 PMID:19074761 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HK1 hexokinase 1 decreases activity ISO cupric chloride results in decreased activity of HK1 protein CTD PMID:22349057 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP cupric chloride results in decreased expression of HMGCR mRNA CTD PMID:34921933 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression EXP cupric chloride results in decreased expression of HMGCS1 mRNA CTD PMID:34921933 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP cupric chloride results in increased expression of HMOX1 mRNA; cupric chloride results in increased expression of HMOX1 protein CTD PMID:17211630 PMID:21242307 PMID:24343273 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 decreases expression EXP cupric chloride results in decreased expression of HSD17B7 mRNA CTD PMID:34921933 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression EXP cupric chloride results in increased expression of HSP90AA1 mRNA CTD PMID:17211630 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA] CTD PMID:20920558 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A affects expression EXP cupric chloride affects the expression of HSPA1A mRNA CTD PMID:20945374 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression EXP cupric chloride results in increased expression of HSPA1B mRNA CTD PMID:17211630 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA] CTD PMID:20920558 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP cupric chloride results in increased expression of HSPA6 mRNA CTD PMID:17211630 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 decreases expression ISO cupric chloride results in decreased expression of HSPA9 protein CTD PMID:29617964 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 increases expression EXP cupric chloride results in increased expression of HSPB1 mRNA CTD PMID:17211630 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G ID2 inhibitor of DNA binding 2 affects expression EXP cupric chloride affects the expression of ID2 mRNA CTD PMID:17211630 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO cupric chloride results in decreased expression of IDH3A protein CTD PMID:29617964 NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945 		JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP cupric chloride results in decreased expression of IDI1 mRNA CTD PMID:34921933 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119 		JBrowse link
G IER2 immediate early response 2 increases expression EXP cupric chloride results in increased expression of IER2 mRNA CTD PMID:17211630 NCBI chr19:13,150,411...13,154,911
Ensembl chr19:13,150,411...13,154,911 		JBrowse link
G IER5 immediate early response 5 increases expression EXP cupric chloride results in increased expression of IER5 mRNA CTD PMID:17211630 NCBI chr 1:181,088,700...181,092,900
Ensembl chr 1:181,088,700...181,092,900 		JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 increases expression EXP cupric chloride results in increased expression of IFIT1 mRNA CTD PMID:17211630 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487 		JBrowse link
G IFNG interferon gamma multiple interactions ISO cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1 insulin like growth factor 1 increases expression ISO cupric chloride results in increased expression of IGF1 mRNA CTD PMID:17211630 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGHMBP2 immunoglobulin mu DNA binding protein 2 increases expression EXP cupric chloride results in increased expression of IGHMBP2 mRNA CTD PMID:17211630 NCBI chr11:68,903,891...68,940,601
Ensembl chr11:68,903,863...68,940,602 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma increases expression EXP cupric chloride results in increased expression of IKBKG mRNA CTD PMID:17211630 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G IL1A interleukin 1 alpha increases secretion EXP cupric chloride results in increased secretion of IL1A protein CTD PMID:22954531 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:23285694 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IMMT inner membrane mitochondrial protein decreases expression ISO cupric chloride results in decreased expression of IMMT protein CTD PMID:29617964 NCBI chr 2:86,143,936...86,195,462
Ensembl chr 2:86,143,932...86,195,472 		JBrowse link
G IRS2 insulin receptor substrate 2 increases expression EXP cupric chloride results in increased expression of IRS2 mRNA CTD PMID:17211630 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP
ISO		 cupric chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
[Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein		 CTD PMID:17211630 PMID:21911303 PMID:30768131 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KCNIP1 potassium voltage-gated channel interacting protein 1 increases expression EXP cupric chloride results in increased expression of KCNIP1 mRNA CTD PMID:34921933 NCBI chr 5:170,353,487...170,736,632
Ensembl chr 5:170,353,487...170,736,632 		JBrowse link
G KDM2A lysine demethylase 2A increases expression EXP cupric chloride results in increased expression of KDM2A mRNA CTD PMID:17211630 NCBI chr11:67,119,263...67,258,082
Ensembl chr11:67,119,263...67,258,082 		JBrowse link
G KDM3A lysine demethylase 3A increases expression EXP cupric chloride results in increased expression of KDM3A mRNA CTD PMID:17211630 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716 		JBrowse link
G KIF5A kinesin family member 5A decreases activity
multiple interactions		 EXP cupric chloride results in decreased activity of KIF5A protein
Cysteine inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Dithiothreitol inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Egtazic Acid inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]		 CTD PMID:24853401 NCBI chr12:57,550,044...57,586,633
Ensembl chr12:57,546,026...57,586,633 		JBrowse link
G KLF6 KLF transcription factor 6 affects expression EXP cupric chloride affects the expression of KLF6 mRNA CTD PMID:17211630 NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281 		JBrowse link
G KNG1 kininogen 1 increases expression ISO cupric chloride results in increased expression of KNG1 mRNA; cupric chloride results in increased expression of KNG2 mRNA CTD PMID:17211630 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 multiple interactions
decreases expression		 ISO PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 protein]
cupric chloride results in decreased expression of LAMP1 mRNA; cupric chloride results in decreased expression of LAMP1 protein		 CTD PMID:32512069 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 multiple interactions
decreases expression		 ISO PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP2 mRNA] CTD PMID:32512069 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase increases expression ISO cupric chloride results in increased expression of LCAT mRNA CTD PMID:17211630 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LOX lysyl oxidase increases activity
multiple interactions		 ISO
EXP		 cupric chloride results in increased activity of LOX protein
Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]		 CTD PMID:22367676 PMID:25044713 NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413 		JBrowse link
G LY6E lymphocyte antigen 6 family member E increases expression ISO cupric chloride results in increased expression of LY6E mRNA CTD PMID:17211630 NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832 		JBrowse link
G MAD2L1BP MAD2L1 binding protein increases expression EXP cupric chloride results in increased expression of MAD2L1BP mRNA CTD PMID:17211630 NCBI chr 6:43,629,540...43,640,941
Ensembl chr 6:43,629,540...43,640,941 		JBrowse link
G MAFG MAF bZIP transcription factor G increases expression EXP cupric chloride results in increased expression of MAFG mRNA CTD PMID:17211630 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735 		JBrowse link
G MAGEA2 MAGE family member A2 increases expression EXP cupric chloride results in increased expression of MAGEA2 mRNA CTD PMID:17211630 NCBI chr  X:152,749,863...152,753,884
Ensembl chr  X:152,749,863...152,753,884 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases expression
multiple interactions		 EXP
ISO		 cupric chloride results in increased expression of MAP1LC3B mRNA
cupric chloride results in increased expression of MAP1LC3B protein modified form
Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]; cupric chloride inhibits the reaction [3-methyladenine results in decreased expression of MAP1LC3B protein modified form]; PP242 promotes the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]		 CTD PMID:17211630 PMID:32512069 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein CTD PMID:20920558 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein CTD PMID:20920558 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]		 CTD PMID:11239917 PMID:20920558 PMID:30768131 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 multiple interactions EXP cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] CTD PMID:19789329 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,410...127,622,436 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 multiple interactions EXP cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] CTD PMID:19789329 NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431 		JBrowse link
G MDH2 malate dehydrogenase 2 increases expression ISO cupric chloride results in increased expression of MDH2 protein CTD PMID:29617964 NCBI chr 7:76,048,106...76,067,508
Ensembl chr 7:76,048,051...76,067,508 		JBrowse link
G MED15 mediator complex subunit 15 increases expression EXP cupric chloride results in increased expression of MED15 mRNA CTD PMID:17211630 NCBI chr22:20,507,610...20,587,619
Ensembl chr22:20,495,913...20,587,632 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase multiple interactions EXP [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein CTD PMID:24193513 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor increases expression EXP cupric chloride results in increased expression of MLLT11 mRNA CTD PMID:17211630 NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544 		JBrowse link
G MMP2 matrix metallopeptidase 2 increases secretion ISO cupric chloride results in increased secretion of MMP2 protein CTD PMID:11045606 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MRPL4 mitochondrial ribosomal protein L4 increases expression EXP cupric chloride results in increased expression of MRPL4 mRNA CTD PMID:17211630 NCBI chr19:10,251,951...10,260,055
Ensembl chr19:10,251,901...10,260,055 		JBrowse link
G MSRB1 methionine sulfoxide reductase B1 increases expression EXP cupric chloride results in increased expression of MSRB1 mRNA CTD PMID:17211630 NCBI chr16:1,938,229...1,943,199
Ensembl chr16:1,938,229...1,943,199 		JBrowse link
G MT1A metallothionein 1A increases expression EXP
ISO		 cupric chloride results in increased expression of MT1A mRNA CTD PMID:17211630 PMID:23174565 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087 		JBrowse link
G MT1B metallothionein 1B multiple interactions
increases expression		 EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1B mRNA]
cupric chloride results in increased expression of MT1B mRNA		 CTD PMID:17211630 PMID:19789329 NCBI chr16:56,651,886...56,653,204
Ensembl chr16:56,651,886...56,653,204 		JBrowse link
G MT1E metallothionein 1E increases expression EXP cupric chloride results in increased expression of MT1E mRNA CTD PMID:17211630 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112 		JBrowse link
G MT1F metallothionein 1F multiple interactions
increases expression
decreases expression		 EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1F mRNA]
cupric chloride results in increased expression of MT1F mRNA
cupric chloride deficiency results in decreased expression of MT1F mRNA		 CTD PMID:17211630 PMID:19789329 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698 		JBrowse link
G MT1G metallothionein 1G multiple interactions
increases expression		 EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1G mRNA]
cupric chloride results in increased expression of MT1G mRNA		 CTD PMID:19789329 PMID:32870474 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065 		JBrowse link
G MT1L metallothionein 1L, pseudogene increases expression EXP cupric chloride results in increased expression of MT1L mRNA CTD PMID:17211630 NCBI chr16:56,617,461...56,618,818
Ensembl chr16:56,617,563...56,618,680 		JBrowse link
G MT1X metallothionein 1X multiple interactions
increases expression
decreases expression		 EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1X mRNA]
cupric chloride results in increased expression of MT1X mRNA
cupric chloride deficiency results in decreased expression of MT1X mRNA		 CTD PMID:17211630 PMID:19789329 PMID:24343273 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MT2A metallothionein 2A multiple interactions
increases expression
affects expression		 EXP
ISO		 cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]
cupric chloride results in increased expression of MT2A mRNA
cupric chloride affects the expression of MT2A mRNA		 CTD PMID:17211630 PMID:17409708 PMID:19789329 PMID:20945374 PMID:23174565 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MTOR mechanistic target of rapamycin kinase increases phosphorylation ISO cupric chloride results in increased phosphorylation of MTOR protein CTD PMID:32512069 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MVD mevalonate diphosphate decarboxylase decreases expression EXP cupric chloride results in decreased expression of MVD mRNA CTD PMID:34921933 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 increases expression EXP cupric chloride results in increased expression of NCF2 mRNA CTD PMID:17211630 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO cupric chloride results in decreased expression of NDUFS1 protein CTD PMID:29617964 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509 		JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO cupric chloride results in decreased expression of NDUFS4 protein CTD PMID:29617964 NCBI chr 5:53,560,639...53,683,338
Ensembl chr 5:53,560,633...53,683,338 		JBrowse link
G NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 decreases expression ISO cupric chloride results in decreased expression of NDUFV1 protein CTD PMID:29617964 NCBI chr11:67,606,936...67,612,554
Ensembl chr11:67,605,653...67,612,554 		JBrowse link
G NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 decreases expression ISO cupric chloride results in decreased expression of NDUFV3 protein CTD PMID:29617964 NCBI chr21:42,893,309...42,913,299
Ensembl chr21:42,879,644...42,913,304 		JBrowse link
G NEFL neurofilament light chain decreases expression ISO cupric chloride results in decreased expression of NEFL protein CTD PMID:29617964 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NEU1 neuraminidase 1 decreases expression EXP cupric chloride results in decreased expression of NEU1 mRNA CTD PMID:34921933 NCBI chr 6:31,857,659...31,862,821
Ensembl chr 6:31,857,659...31,862,905 		JBrowse link
G NFIX nuclear factor I X decreases expression EXP cupric chloride results in decreased expression of NFIX mRNA CTD PMID:17211630 NCBI chr19:12,995,475...13,098,796
Ensembl chr19:12,995,475...13,098,796 		JBrowse link
G NFKBIA NFKB inhibitor alpha decreases expression ISO cupric chloride results in decreased expression of NFKBIA protein CTD PMID:24530511 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO cupric chloride results in increased expression of NME1 protein CTD PMID:29617964 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]
cupric chloride results in increased expression of NOS2 protein		 CTD PMID:8975779 PMID:23313662 PMID:24170445 PMID:24530511 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NUDT5 nudix hydrolase 5 increases expression EXP cupric chloride results in increased expression of NUDT5 mRNA CTD PMID:34921933 NCBI chr10:12,165,330...12,195,891
Ensembl chr10:12,165,330...12,196,144 		JBrowse link
G NUP107 nucleoporin 107 increases expression EXP cupric chloride results in increased expression of NUP107 mRNA CTD PMID:17211630 NCBI chr12:68,686,978...68,745,809
Ensembl chr12:68,686,951...68,745,809 		JBrowse link
G P2RX2 purinergic receptor P2X 2 multiple interactions ISO cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr12:132,618,776...132,622,388
Ensembl chr12:132,618,776...132,622,388 		JBrowse link
G P3H4 prolyl 3-hydroxylase family member 4 (inactive) affects expression EXP cupric chloride affects the expression of P3H4 mRNA CTD PMID:17211630 NCBI chr17:41,801,953...41,811,949
Ensembl chr17:41,801,947...41,812,604 		JBrowse link
G PALLD palladin, cytoskeletal associated protein increases expression EXP cupric chloride results in increased expression of PALLD mRNA CTD PMID:17211630 NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457 		JBrowse link
G PAQR8 progestin and adipoQ receptor family member 8 decreases expression EXP cupric chloride results in decreased expression of PAQR8 mRNA CTD PMID:17211630 NCBI chr 6:52,362,151...52,407,777
Ensembl chr 6:52,361,421...52,407,777 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases expression		 EXP
ISO		 [Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein
cupric chloride results in increased expression of PARP1 protein		 CTD PMID:19789329 PMID:21035945 PMID:23313662 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCM1 pericentriolar material 1 decreases expression EXP cupric chloride results in decreased expression of PCM1 mRNA CTD PMID:17211630 NCBI chr 8:17,922,988...18,029,948
Ensembl chr 8:17,922,842...18,029,948 		JBrowse link
G PCYT2 phosphate cytidylyltransferase 2, ethanolamine decreases expression EXP cupric chloride results in decreased expression of PCYT2 mRNA CTD PMID:34921933 NCBI chr17:81,900,958...81,911,399
Ensembl chr17:81,900,958...81,911,432 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 decreases expression ISO cupric chloride results in decreased expression of PDIA3 protein CTD PMID:29617964 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279 		JBrowse link
G PDZK1 PDZ domain containing 1 decreases expression EXP cupric chloride results in decreased expression of PDZK1 mRNA CTD PMID:17211630 NCBI chr 1:145,670,852...145,707,400
Ensembl chr 1:145,670,852...145,708,148 		JBrowse link
G PEG10 paternally expressed 10 decreases expression EXP cupric chloride results in decreased expression of PEG10 mRNA CTD PMID:17211630 NCBI chr 7:94,656,325...94,669,695
Ensembl chr 7:94,656,325...94,669,695 		JBrowse link
G PFKP phosphofructokinase, platelet increases expression EXP cupric chloride results in increased expression of PFKP mRNA CTD PMID:34921933 NCBI chr10:3,067,548...3,136,805
Ensembl chr10:3,066,333...3,137,718 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 increases expression ISO cupric chloride results in increased expression of PGAM1 protein CTD PMID:29617964 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444 		JBrowse link
G PGR progesterone receptor multiple interactions
increases expression		 EXP cupric chloride promotes the reaction [Estradiol results in increased expression of PGR mRNA]; cupric chloride promotes the reaction [Estradiol results in increased expression of PGR protein]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR mRNA]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR protein]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR protein]
cupric chloride results in increased expression of PGR mRNA; cupric chloride results in increased expression of PGR protein		 CTD PMID:12746304 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein decreases expression EXP cupric chloride results in decreased expression of PHYHIP mRNA CTD PMID:17211630 NCBI chr 8:22,219,703...22,232,099
Ensembl chr 8:22,219,703...22,232,101 		JBrowse link
G PITPNC1 phosphatidylinositol transfer protein cytoplasmic 1 decreases expression EXP cupric chloride results in decreased expression of PITPNC1 mRNA CTD PMID:17211630 NCBI chr17:67,377,281...67,697,256
Ensembl chr17:67,377,281...67,697,256 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions		 EXP cupric chloride results in increased expression of PMAIP1 mRNA
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of PMAIP1 protein		 CTD PMID:20713136 PMID:21035945 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G POMP proteasome maturation protein increases expression EXP cupric chloride results in increased expression of POMP mRNA CTD PMID:17211630 NCBI chr13:28,659,130...28,678,959
Ensembl chr13:28,659,065...28,678,959 		JBrowse link
G PRDX1 peroxiredoxin 1 increases expression EXP cupric chloride results in increased expression of PRDX1 mRNA CTD PMID:17211630 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
G PRDX3 peroxiredoxin 3 decreases expression ISO cupric chloride results in decreased expression of PRDX3 protein CTD PMID:29617964 NCBI chr10:119,167,720...119,178,812
Ensembl chr10:119,167,720...119,178,812 		JBrowse link
G PRNP prion protein multiple interactions
increases expression		 ISO [NADP co-treated with cupric chloride] promotes the reaction [PRNP protein binds to PRNP protein]
bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein]
cupric chloride results in increased expression of PRNP mRNA; cupric chloride results in increased expression of PRNP protein		 CTD PMID:16148034 PMID:16990274 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa multiple interactions EXP ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; aspartyl-alanyl-histidyl-lysine inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; cupric chloride binds to and results in decreased activity of PROC protein CTD PMID:11820775 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G PSMB2 proteasome 20S subunit beta 2 increases expression EXP cupric chloride results in increased expression of PSMB2 mRNA CTD PMID:17211630 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526 		JBrowse link
G PSMB3 proteasome 20S subunit beta 3 increases expression EXP cupric chloride results in increased expression of PSMB3 mRNA CTD PMID:17211630 NCBI chr17:38,752,741...38,764,225
Ensembl chr17:38,752,741...38,764,225 		JBrowse link
G PSMB7 proteasome 20S subunit beta 7 increases expression EXP cupric chloride results in increased expression of PSMB7 mRNA CTD PMID:17211630 NCBI chr 9:124,353,465...124,415,442
Ensembl chr 9:124,353,465...124,415,444 		JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 increases expression EXP cupric chloride results in increased expression of PSMC1 mRNA CTD PMID:17211630 NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429 		JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 increases expression EXP cupric chloride results in increased expression of PSMC4 mRNA CTD PMID:17211630 NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764 		JBrowse link
G PSMD1 proteasome 26S subunit, non-ATPase 1 increases expression EXP cupric chloride results in increased expression of PSMD1 mRNA CTD PMID:17211630 NCBI chr 2:231,056,867...231,172,827
Ensembl chr 2:231,056,845...231,173,116 		JBrowse link
G PSMD11 proteasome 26S subunit, non-ATPase 11 increases expression EXP cupric chloride results in increased expression of PSMD11 mRNA CTD PMID:17211630 NCBI chr17:32,444,510...32,483,319
Ensembl chr17:32,444,379...32,483,319 		JBrowse link
G PSMD13 proteasome 26S subunit, non-ATPase 13 increases expression EXP cupric chloride results in increased expression of PSMD13 mRNA CTD PMID:17211630 NCBI chr11:236,976...252,984
Ensembl chr11:236,966...252,984 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 increases expression EXP cupric chloride results in increased expression of PSMD14 mRNA CTD PMID:17211630 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717 		JBrowse link
G PSMD2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 increases expression EXP cupric chloride results in increased expression of PSMD2 mRNA CTD PMID:17211630 NCBI chr 3:184,299,241...184,309,050
Ensembl chr 3:184,299,198...184,309,050 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression ISO cupric chloride results in increased expression of PTGS2 protein CTD PMID:23313662 PMID:24170445 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O decreases expression EXP cupric chloride results in decreased expression of PTPRO mRNA CTD PMID:17211630 NCBI chr12:15,322,508...15,598,331
Ensembl chr12:15,322,257...15,602,175 		JBrowse link
G PURA purine rich element binding protein A decreases expression ISO cupric chloride results in decreased expression of PURA protein CTD PMID:29617964 NCBI chr 5:140,114,109...140,125,619
Ensembl chr 5:140,107,777...140,125,619 		JBrowse link
G QKI QKI, KH domain containing RNA binding increases expression EXP cupric chloride results in increased expression of QKI mRNA CTD PMID:17211630 NCBI chr 6:163,414,718...163,578,592
Ensembl chr 6:163,414,000...163,578,592 		JBrowse link
G RALGAPA1 Ral GTPase activating protein catalytic subunit alpha 1 affects expression EXP cupric chloride affects the expression of RALGAPA1 mRNA CTD PMID:17211630 NCBI chr14:35,538,356...35,809,295
Ensembl chr14:35,538,352...35,809,304 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO cupric chloride results in increased phosphorylation of and affects the localization of RELA protein CTD PMID:24530511 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RHOB ras homolog family member B decreases expression EXP cupric chloride results in decreased expression of ARHB mRNA CTD PMID:17211630 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440 		JBrowse link
G RNF181 ring finger protein 181 affects expression EXP cupric chloride affects the expression of RNF181 mRNA CTD PMID:17211630 NCBI chr 2:85,595,745...85,597,708
Ensembl chr 2:85,595,725...85,597,708 		JBrowse link
G RPL32 ribosomal protein L32 affects expression EXP cupric chloride affects the expression of RPL32 mRNA CTD PMID:17211630 NCBI chr 3:12,834,485...12,841,582
Ensembl chr 3:12,834,485...12,841,582 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 increases phosphorylation ISO cupric chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:32512069 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression EXP cupric chloride results in increased expression of RRAD mRNA CTD PMID:17211630 NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,679...66,925,536 		JBrowse link
G RYBP RING1 and YY1 binding protein affects expression EXP cupric chloride affects the expression of RYBP mRNA CTD PMID:17211630 NCBI chr 3:72,374,593...72,446,623
Ensembl chr 3:72,371,825...72,446,621 		JBrowse link
G SBDS SBDS ribosome maturation factor increases expression EXP cupric chloride results in increased expression of SBDS mRNA CTD PMID:17211630 NCBI chr 7:66,987,680...66,995,586
Ensembl chr 7:66,987,680...66,995,693 		JBrowse link
G SCD stearoyl-CoA desaturase decreases expression EXP cupric chloride results in decreased expression of SCD mRNA CTD PMID:34921933 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SCO2 synthesis of cytochrome C oxidase 2 multiple interactions EXP cupric chloride promotes the reaction [Bezafibrate results in increased activity of SCO2 protein mutant form] CTD PMID:22515166 NCBI chr22:50,523,568...50,526,442
Ensembl chr22:50,523,568...50,526,461 		JBrowse link
G SDF2 stromal cell derived factor 2 increases expression EXP cupric chloride results in increased expression of SDF2 mRNA CTD PMID:17211630 NCBI chr17:28,648,346...28,662,194
Ensembl chr17:28,648,346...28,662,189 		JBrowse link
G SELENOK selenoprotein K increases expression EXP cupric chloride results in increased expression of SELENOK mRNA CTD PMID:17211630 NCBI chr 3:53,884,417...53,891,859
Ensembl chr 3:53,884,417...53,891,885 		JBrowse link
G SELENOP selenoprotein P decreases expression EXP cupric chloride results in decreased expression of SELENOP mRNA CTD PMID:17211630 NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392 		JBrowse link
G SEPTIN4 septin 4 decreases expression ISO cupric chloride results in decreased expression of SEPTIN4 protein CTD PMID:29617964 NCBI chr17:58,520,256...58,544,328
Ensembl chr17:58,520,250...58,544,368 		JBrowse link
G SEPTIN8 septin 8 decreases expression ISO cupric chloride results in decreased expression of SEPTIN8 protein CTD PMID:29617964 NCBI chr 5:132,750,819...132,780,083
Ensembl chr 5:132,750,819...132,807,241 		JBrowse link
G SERPINF1 serpin family F member 1 increases expression ISO cupric chloride results in increased expression of SERPINF1 mRNA CTD PMID:17211630 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G SHANK2 SH3 and multiple ankyrin repeat domains 2 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein CTD PMID:25007851 NCBI chr11:70,467,854...71,253,228
Ensembl chr11:70,467,854...71,252,577 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,212 		JBrowse link
G SIRT7 sirtuin 7 increases expression EXP cupric chloride results in increased expression of SIRT7 mRNA CTD PMID:17211630 NCBI chr17:81,911,939...81,918,176
Ensembl chr17:81,911,939...81,921,323 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 multiple interactions EXP cupric chloride inhibits the reaction [SLC11A2 protein results in increased uptake of Iron] CTD PMID:12220667 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566 		JBrowse link
G SLC13A3 solute carrier family 13 member 3 decreases expression EXP cupric chloride results in decreased expression of SLC13A3 mRNA CTD PMID:17211630 NCBI chr20:46,557,828...46,684,485
Ensembl chr20:46,557,823...46,684,467 		JBrowse link
G SLC22A18 solute carrier family 22 member 18 increases expression ISO cupric chloride results in increased expression of SLC22A18 mRNA CTD PMID:17211630 NCBI chr11:2,899,691...2,925,246
Ensembl chr11:2,899,721...2,925,246 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases expression EXP cupric chloride results in increased expression of SLC2A1 mRNA CTD PMID:15741220 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC30A1 solute carrier family 30 member 1 increases expression EXP cupric chloride results in increased expression of SLC30A1 mRNA CTD PMID:24343273 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161 		JBrowse link
G SLC31A1 solute carrier family 31 member 1 decreases expression
multiple interactions		 ISO
EXP		 cupric chloride results in decreased expression of SLC31A1 protein
SLC31A1 protein results in increased susceptibility to [cupric chloride results in increased abundance of Copper]		 CTD PMID:24316150 PMID:24800945 PMID:32278528 NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492 		JBrowse link
G SNCA synuclein alpha affects folding EXP cupric chloride affects the folding of SNCA protein CTD PMID:11553618 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
decreases activity
decreases expression
increases response to substance		 EXP
ISO		 Carnosine inhibits the reaction [cupric chloride results in decreased activity of SOD1 protein]; cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form results in increased susceptibility to cupric chloride]; SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]
cupric chloride results in decreased expression of SOD1 protein		 CTD PMID:15812313 PMID:24691167 PMID:29617964 PMID:32745495 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 decreases expression EXP cupric chloride results in decreased expression of SORBS1 mRNA CTD PMID:17211630 NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414 		JBrowse link
G SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression EXP cupric chloride results in increased expression of SPSB1 mRNA CTD PMID:17211630 NCBI chr 1:9,292,894...9,369,532
Ensembl chr 1:9,292,894...9,369,532 		JBrowse link
G SQLE squalene epoxidase decreases expression EXP cupric chloride results in decreased expression of SQLE mRNA CTD PMID:34921933 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SQSTM1 sequestosome 1 increases expression
multiple interactions		 EXP
ISO		 cupric chloride results in increased expression of SQSTM1 mRNA
Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]; PP242 inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]		 CTD PMID:17211630 PMID:23313662 PMID:32512069 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 decreases expression EXP cupric chloride results in decreased expression of SREBF2 mRNA CTD PMID:34921933 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,079...41,907,307 		JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 decreases expression EXP cupric chloride results in decreased expression of ST6GAL1 mRNA CTD PMID:17211630 NCBI chr 3:186,930,526...187,078,553
Ensembl chr 3:186,930,325...187,078,553 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 decreases expression EXP cupric chloride results in decreased expression of STARD4 mRNA CTD PMID:34921933 NCBI chr 5:111,496,033...111,512,535
Ensembl chr 5:111,496,033...111,512,590 		JBrowse link
G STAU1 staufen double-stranded RNA binding protein 1 decreases expression EXP cupric chloride results in decreased expression of STAU mRNA CTD PMID:17211630 NCBI chr20:49,113,339...49,219,295
Ensembl chr20:49,113,339...49,188,367 		JBrowse link
G STMN1 stathmin 1 decreases expression ISO cupric chloride results in decreased expression of STMN1 protein CTD PMID:29617964 NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991 		JBrowse link
G SYN2 synapsin II decreases expression ISO cupric chloride results in decreased expression of SYN2 protein CTD PMID:29617964 NCBI chr 3:12,004,388...12,192,032
Ensembl chr 3:12,004,388...12,192,032 		JBrowse link
G TAF7L TATA-box binding protein associated factor 7 like increases expression EXP cupric chloride results in increased expression of TAF7L mRNA CTD PMID:17211630 NCBI chr  X:101,268,257...101,293,083
Ensembl chr  X:101,268,253...101,293,057 		JBrowse link
G TALDO1 transaldolase 1 increases expression EXP cupric chloride results in increased expression of TALDO1 mRNA CTD PMID:17211630 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012 		JBrowse link
G TARDBP TAR DNA binding protein multiple interactions EXP cupric chloride inhibits the reaction [Paraquat affects the localization of TARDBP protein] CTD PMID:22879928 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528 		JBrowse link
G TFDP2 transcription factor Dp-2 affects expression EXP cupric chloride affects the expression of TFDP2 mRNA CTD PMID:17211630 NCBI chr 3:141,944,428...142,149,544
Ensembl chr 3:141,944,428...142,149,544 		JBrowse link
G TFEB transcription factor EB decreases expression
multiple interactions		 ISO cupric chloride results in decreased expression of TFEB mRNA; cupric chloride results in decreased expression of TFEB protein
PP242 inhibits the reaction [cupric chloride results in decreased expression of TFEB protein]		 CTD PMID:32512069 NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259 		JBrowse link
G TKT transketolase increases expression EXP cupric chloride results in increased expression of TKT mRNA CTD PMID:17211630 NCBI chr 3:53,224,712...53,256,022
Ensembl chr 3:53,224,712...53,256,052 		JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 decreases expression EXP cupric chloride results in decreased expression of TMED2 mRNA CTD PMID:17211630 NCBI chr12:123,584,552...123,598,582
Ensembl chr12:123,584,533...123,598,582 		JBrowse link
G TMEM97 transmembrane protein 97 decreases expression EXP cupric chloride results in decreased expression of TMEM97 mRNA CTD PMID:34921933 NCBI chr17:28,319,200...28,328,685
Ensembl chr17:28,319,200...28,328,685 		JBrowse link
G TNF tumor necrosis factor increases secretion
multiple interactions
increases expression		 EXP
ISO		 cupric chloride results in increased secretion of TNF protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; SC 514 inhibits the reaction [cupric chloride results in increased secretion of TNF protein]
cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
cupric chloride results in increased expression of TNF protein		 CTD PMID:22954531 PMID:23285694 PMID:23313662 PMID:24170445 PMID:24530511 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 affects expression
multiple interactions
decreases expression
increases expression		 ISO
EXP		 cupric chloride affects the expression of TRP53 mRNA
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]
cupric chloride results in decreased expression of TRP53 protein
cupric chloride results in increased expression of TRP53 protein		 CTD PMID:23313662 PMID:24170445 PMID:29803612 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TP73 tumor protein p73 affects expression
increases expression		 ISO cupric chloride affects the expression of TRP73 protein
cupric chloride results in increased expression of TRP73 protein		 CTD PMID:23313662 PMID:24170445 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
G TPM1 tropomyosin 1 increases expression ISO cupric chloride results in increased expression of TPM1 protein CTD PMID:29617964 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,632...63,071,915 		JBrowse link
G TPPP tubulin polymerization promoting protein increases expression ISO cupric chloride results in increased expression of TPPP protein CTD PMID:29617964 NCBI chr 5:659,862...700,727
Ensembl chr 5:659,862...693,352 		JBrowse link
G TRAF5 TNF receptor associated factor 5 increases expression EXP cupric chloride results in increased expression of TRAF5 mRNA CTD PMID:17211630 NCBI chr 1:211,326,635...211,374,946
Ensembl chr 1:211,326,615...211,374,946 		JBrowse link
G TRIB3 tribbles pseudokinase 3 increases expression EXP cupric chloride results in increased expression of TRIB3 mRNA CTD PMID:17211630 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559 		JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [cupric chloride results in increased abundance of Copper] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:107,713,221...107,775,988
Ensembl chr  X:107,713,221...107,777,342 		JBrowse link
G TXN thioredoxin increases expression EXP cupric chloride results in increased expression of TXN mRNA CTD PMID:17211630 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TXNL1 thioredoxin like 1 increases expression EXP cupric chloride results in increased expression of TXNL1 mRNA CTD PMID:17211630 NCBI chr18:56,597,209...56,638,592
Ensembl chr18:56,597,209...56,651,600 		JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP cupric chloride results in increased expression of TXNRD1 mRNA CTD PMID:17211630 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307 		JBrowse link
G TYR tyrosinase multiple interactions EXP cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]] CTD PMID:11092760 NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759 		JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions EXP cupric chloride promotes the reaction [Dimethyldithiocarbamate results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; cupric chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128 		JBrowse link
G UBC ubiquitin C increases expression EXP cupric chloride results in increased expression of UBC mRNA CTD PMID:17211630 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 increases expression EXP cupric chloride results in increased expression of UBR5 mRNA CTD PMID:17211630 NCBI chr 8:102,252,273...102,412,700
Ensembl chr 8:102,252,273...102,412,759 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 increases expression ISO cupric chloride results in increased expression of UCHL1 protein CTD PMID:29617964 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 increases expression EXP cupric chloride results in increased expression of UFD1 mRNA CTD PMID:17211630 NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202 		JBrowse link
G UNC79 unc-79 homolog, NALCN channel complex subunit decreases expression EXP cupric chloride results in decreased expression of UNC79 mRNA CTD PMID:34921933 NCBI chr14:93,333,182...93,707,876
Ensembl chr14:93,333,219...93,707,876 		JBrowse link
G UNKL unk like zinc finger increases expression EXP cupric chloride results in increased expression of UNKL mRNA CTD PMID:17211630 NCBI chr16:1,363,205...1,414,704
Ensembl chr16:1,363,205...1,414,751 		JBrowse link
G UQCRC1 ubiquinol-cytochrome c reductase core protein 1 increases expression ISO cupric chloride results in increased expression of UQCRC1 protein CTD PMID:29617964 NCBI chr 3:48,599,002...48,609,646
Ensembl chr 3:48,599,002...48,610,976 		JBrowse link
G UQCRH ubiquinol-cytochrome c reductase hinge protein decreases expression ISO cupric chloride results in decreased expression of UQCRH protein CTD PMID:29617964 NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776 		JBrowse link
G UTP11 UTP11 small subunit processome component increases expression EXP cupric chloride results in increased expression of UTP11 mRNA CTD PMID:17211630 NCBI chr 1:38,012,734...38,024,820
Ensembl chr 1:38,009,258...38,024,820 		JBrowse link
G VDAC1 voltage dependent anion channel 1 increases expression ISO cupric chloride results in increased expression of VDAC1 protein CTD PMID:29617964 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
G VDAC2 voltage dependent anion channel 2 increases expression ISO cupric chloride results in increased expression of VDAC2 protein CTD PMID:29617964 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448 		JBrowse link
G VEGFA vascular endothelial growth factor A increases expression EXP cupric chloride results in increased expression of VEGFA mRNA CTD PMID:15741220 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VPS13B vacuolar protein sorting 13 homolog B affects expression EXP cupric chloride affects the expression of VPS13B mRNA CTD PMID:17211630 NCBI chr 8:99,013,274...99,877,580
Ensembl chr 8:99,013,266...99,877,580 		JBrowse link
G WDR74 WD repeat domain 74 affects expression EXP cupric chloride affects the expression of WDR74 mRNA CTD PMID:17211630 NCBI chr11:62,832,905...62,841,809
Ensembl chr11:62,832,342...62,841,809 		JBrowse link
G ZBTB5 zinc finger and BTB domain containing 5 decreases expression EXP cupric chloride results in decreased expression of ZBTB5 mRNA CTD PMID:34921933 NCBI chr 9:37,438,102...37,465,450
Ensembl chr 9:37,438,102...37,465,450 		JBrowse link
G ZNF12 zinc finger protein 12 increases expression EXP cupric chloride results in increased expression of ZNF12 mRNA CTD PMID:17211630 NCBI chr 7:6,688,433...6,706,947
Ensembl chr 7:6,688,433...6,706,947 		JBrowse link
G ZNF197 zinc finger protein 197 affects expression EXP cupric chloride affects the expression of ZNF197 mRNA CTD PMID:17211630 NCBI chr 3:44,625,036...44,648,471
Ensembl chr 3:44,584,888...44,648,471 		JBrowse link
G ZNRD2 zinc ribbon domain containing 2 increases expression EXP cupric chloride results in increased expression of ZNRD2 mRNA CTD PMID:17211630 NCBI chr11:65,570,477...65,571,888
Ensembl chr11:65,570,460...65,573,942 		JBrowse link
G ZSWIM6 zinc finger SWIM-type containing 6 affects expression EXP cupric chloride affects the expression of ZSWIM6 mRNA CTD PMID:17211630 NCBI chr 5:61,332,258...61,546,172
Ensembl chr 5:61,332,258...61,546,172 		JBrowse link
trifluoperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases activity EXP Trifluoperazine results in increased activity of ABCB1 protein CTD PMID:2900677 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions
increases activity
decreases expression		 ISO energostim inhibits the reaction [Trifluoperazine results in decreased expression of ACHE protein]
Trifluoperazine results in increased activity of ACHE protein		 CTD PMID:15232633 PMID:29614332 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:19233221 PMID:21544200 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H multiple interactions EXP [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA CTD PMID:28366621 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP Trifluoperazine results in increased expression of BAX protein CTD PMID:21475906 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP Trifluoperazine results in decreased expression of BCL2 protein CTD PMID:21475906 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of CAMK2A protein] CTD PMID:19233221 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,093 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO
EXP		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein] CTD PMID:21544200 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CD44 CD44 molecule (Indian blood group) multiple interactions ISO Trifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein] CTD PMID:9929743 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:21544200 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365 		JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 increases oxidation EXP FMO2 protein results in increased oxidation of Trifluoperazine CTD PMID:26062974 NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686 		JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions EXP Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:15627515 NCBI chr 6:29,602,238...29,633,183
Ensembl chr 6:29,555,629...29,633,976 		JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions EXP Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:15627515 NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha decreases expression EXP Trifluoperazine results in decreased expression of HIF1A protein CTD PMID:18822394 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G IL12B interleukin 12B multiple interactions ISO Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IL12B protein] CTD PMID:16249388 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 multiple interactions EXP Trifluoperazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:21158687 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 decreases activity ISO Trifluoperazine results in decreased activity of KCNN2 protein CTD PMID:10915830 NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 multiple interactions EXP [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA CTD PMID:28366621 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO
EXP		 Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK1 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Trifluoperazine inhibits the reaction [Dinoprost results in increased activity of MAPK1 protein] CTD PMID:11914123 PMID:21544200 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein] CTD PMID:21544200 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO
EXP		 Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK3 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Trifluoperazine inhibits the reaction [Dinoprost results in increased activity of MAPK3 protein] CTD PMID:11914123 PMID:21544200 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:21544200 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MT1A metallothionein 1A increases expression ISO Trifluoperazine results in increased expression of MT1A mRNA CTD PMID:8128501 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MTOR protein] CTD PMID:21544200 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MYL9 myosin light chain 9 multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MYL9 protein]; Trifluoperazine inhibits the reaction [Ionomycin results in increased phosphorylation of MYL9 protein] CTD PMID:19233221 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447 		JBrowse link
G NEFL neurofilament light chain multiple interactions ISO Trifluoperazine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:31969611 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 decreases activity ISO Trifluoperazine results in decreased activity of NR3C1 protein CTD PMID:7887964 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO
EXP		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] CTD PMID:21544200 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PINK1 PTEN induced kinase 1 multiple interactions EXP [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase multiple interactions
affects localization		 EXP PRKN protein affects the reaction [Trifluoperazine affects the localization of PRKN protein] CTD PMID:28366621 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PRL prolactin increases expression EXP Trifluoperazine results in increased expression of PRL protein CTD PMID:2136057 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G REL REL proto-oncogene, NF-kB subunit multiple interactions ISO Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased localization of REL protein] CTD PMID:16249388 NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions ISO Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G SLC5A6 solute carrier family 5 member 6 multiple interactions EXP Trifluoperazine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 2:27,199,587...27,212,787
Ensembl chr 2:27,199,587...27,212,958 		JBrowse link
G TFEB transcription factor EB multiple interactions EXP [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259 		JBrowse link
G TNFSF11 TNF superfamily member 11 decreases activity ISO Trifluoperazine results in decreased activity of TNFSF11 CTD PMID:21869564 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G UGT1A4 UDP glucuronosyltransferase family 1 member A4 multiple interactions
increases activity
increases glucuronidation		 EXP Finasteride inhibits the reaction [UGT1A4 protein results in increased glucuronidation of Trifluoperazine]; hecogenin inhibits the reaction [UGT1A4 protein results in increased glucuronidation of Trifluoperazine]; licochalcone A inhibits the reaction [Trifluoperazine results in increased activity of UGT1A4 protein]; Trifluoperazine inhibits the reaction [UGT1A4 protein results in increased glucuronidation of afloqualone] CTD PMID:15135306 PMID:15475412 PMID:25393417 PMID:25448279 PMID:26875642 More... NCBI chr 2:233,718,736...233,773,300
Ensembl chr 2:233,718,736...233,773,300 		JBrowse link
zinc dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP
ISO		 zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB1 mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]		 CTD PMID:19714248 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB6 ATP binding cassette subfamily B member 6 (Langereis blood group) multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB6 mRNA] CTD PMID:22202117 NCBI chr 2:219,209,772...219,218,958
Ensembl chr 2:219,209,772...219,218,994 		JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO [zinc chloride results in increased abundance of Zinc] inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of ACHE protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein] CTD PMID:19429256 PMID:29233033 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACO2 aconitase 2 multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in decreased activity of ACO2 protein CTD PMID:16624386 NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273 		JBrowse link
G ACTB actin beta multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of ACTB mRNA CTD PMID:31588059 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G ADAM2 ADAM metallopeptidase domain 2 decreases expression EXP zinc chloride results in decreased expression of ADAM2 mRNA CTD PMID:16870260 NCBI chr 8:39,743,735...39,838,227
Ensembl chr 8:39,743,735...39,838,227 		JBrowse link
G ADGRE1 adhesion G protein-coupled receptor E1 multiple interactions
increases expression		 ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein] CTD PMID:18509044 NCBI chr19:6,887,579...6,940,450
Ensembl chr19:6,887,566...6,940,459 		JBrowse link
G ADM adrenomedullin multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ADM mRNA] CTD PMID:22202117 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADORA1 adenosine A1 receptor multiple interactions ISO zinc chloride inhibits the reaction [N(6)-cyclohexyladenosine binds to ADORA1 protein] CTD PMID:10413299 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G AFP alpha fetoprotein decreases expression EXP zinc chloride results in decreased expression of AFP mRNA CTD PMID:18947441 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174 		JBrowse link
G AGO2 argonaute RISC catalytic component 2 multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of AGO2 mRNA; [Clioquinol co-treated with zinc chloride] results in decreased expression of AGO2 protein CTD PMID:22415087 NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633 		JBrowse link
G AK4 adenylate kinase 4 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of AK4 mRNA] CTD PMID:22202117 NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 ISO zinc chloride results in increased phosphorylation of AKT1 protein
wortmannin inhibits the reaction [zinc chloride results in increased phosphorylation of AKT1 protein]		 CTD PMID:11340092 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions ISO
EXP		 [zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]] which affects the abundance of Mercury; zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]
lead nitrate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]; triethyllead acetate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]; zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]
zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of ALAD protein]		 CTD PMID:2061546 PMID:14615064 PMID:22413763 PMID:24619859 PMID:24679358 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ALDOA mRNA] CTD PMID:22202117 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G ALDOC aldolase, fructose-bisphosphate C multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ALDOC mRNA] CTD PMID:22202117 NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions
increases activity		 ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of ALPL mRNA
zinc chloride results in increased activity of ALPL protein
Cadmium inhibits the reaction [zinc chloride results in increased activity of ALPL protein]; zinc chloride inhibits the reaction [Cadmium results in decreased activity of ALPL protein]		 CTD PMID:19913120 PMID:26214600 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G ANG angiogenin multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANG mRNA] CTD PMID:22202117 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G ANGPTL4 angiopoietin like 4 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANGPTL4 mRNA] CTD PMID:22202117 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370 		JBrowse link
G ANKRD37 ankyrin repeat domain 37 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKRD37 mRNA] CTD PMID:22202117 NCBI chr 4:185,396,841...185,400,723
Ensembl chr 4:185,396,021...185,400,628 		JBrowse link
G ANKZF1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKZF1 mRNA] CTD PMID:22202117 NCBI chr 2:219,229,806...219,236,679
Ensembl chr 2:219,229,783...219,236,679 		JBrowse link
G AR androgen receptor multiple interactions ISO Androgens inhibits the reaction [zinc chloride inhibits the reaction [Androgens binds to AR protein]]; Dithiothreitol inhibits the reaction [zinc chloride inhibits the reaction [Androgens binds to AR protein]]; zinc chloride inhibits the reaction [Androgens binds to AR protein] CTD PMID:6323860 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARG2 arginase 2 increases expression EXP zinc chloride results in increased expression of ARG2 mRNA CTD PMID:18947441 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ARRB2 arrestin beta 2 affects localization EXP zinc chloride affects the localization of ARRB2 protein CTD PMID:16959833 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G ATF2 activating transcription factor 2 multiple interactions ISO [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein] CTD PMID:30768131 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G ATF4 activating transcription factor 4 decreases expression EXP zinc chloride results in decreased expression of ATF4 mRNA CTD PMID:18947441 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 decreases expression EXP zinc chloride results in decreased expression of ATP6V1B2 mRNA CTD PMID:18947441 NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,226,819 		JBrowse link
G ATP7B ATPase copper transporting beta decreases expression
increases expression		 EXP zinc chloride results in decreased expression of ATP7B mRNA
zinc chloride results in increased expression of ATP7B mRNA		 CTD PMID:18947441 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G BAG3 BAG cochaperone 3 increases expression
multiple interactions		 EXP zinc chloride results in increased expression of BAG3 mRNA
zinc chloride results in increased expression of and affects the localization of BAG3 protein		 CTD PMID:12706811 PMID:16870260 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO		 [Citric Acid co-treated with zinc chloride] results in increased expression of BAX protein
zinc chloride promotes the reaction [Doxorubicin results in increased expression of BAX mRNA]
zinc chloride affects the reaction [Cadmium Chloride results in increased expression of BAX protein]		 CTD PMID:16624386 PMID:19714248 PMID:28390674 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BBC3 BCL2 binding component 3 multiple interactions ISO zinc chloride promotes the reaction [Doxorubicin results in increased expression of BBC3 mRNA] CTD PMID:19714248 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP
ISO		 [Citric Acid co-treated with zinc chloride] results in decreased expression of BCL2 protein; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BCL2 mRNA]; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BCL2 protein]; zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BCL2 mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of BCL2 mRNA]		 CTD PMID:16624386 PMID:17786326 PMID:19714248 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2A1 BCL2 related protein A1 increases expression EXP zinc chloride results in increased expression of BCL2A1 mRNA CTD PMID:21540303 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in decreased expression of BCL2L1 protein CTD PMID:16624386 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride affects the expression of BDNF mRNA] CTD PMID:29548726 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of BGLAP mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of BGLAP mRNA CTD PMID:19913120 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BHLHE40 mRNA] CTD PMID:22202117 NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BNIP3L mRNA] CTD PMID:22202117 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636 		JBrowse link
G BOP1 BOP1 ribosomal biogenesis factor multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BOP1 mRNA] CTD PMID:22202117 NCBI chr 8:144,262,045...144,291,438
Ensembl chr 8:144,262,045...144,291,438 		JBrowse link
G C3 complement C3 increases expression EXP zinc chloride results in increased expression of C3 mRNA CTD PMID:19428942 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CA13 carbonic anhydrase 13 increases expression ISO zinc chloride results in increased expression of CAR13 mRNA CTD PMID:19000923 NCBI chr 8:85,245,458...85,284,073
Ensembl chr 8:85,220,587...85,284,073 		JBrowse link
G CA9 carbonic anhydrase 9 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CA9 mRNA] CTD PMID:22202117 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H decreases activity
multiple interactions		 ISO zinc chloride results in decreased activity of CACNA1H protein
zinc chloride inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]		 CTD PMID:34286406 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,106...1,221,771 		JBrowse link
G CALD1 caldesmon 1 increases expression EXP zinc chloride results in increased expression of CALD1 mRNA CTD PMID:16870260 NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729 		JBrowse link
G CASP12 caspase 12 (gene/pseudogene) multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in increased activity of CASP12 protein CTD PMID:16624386 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in increased activity of CASP3 protein CTD PMID:16624386 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 mRNA] CTD PMID:28390674 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions
increases expression
increases activity		 ISO
EXP		 zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein]
zinc chloride results in increased expression of CAT mRNA
zinc chloride results in increased activity of CAT protein		 CTD PMID:9330853 PMID:19429256 PMID:23726800 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCDC102B coiled-coil domain containing 102B increases expression EXP zinc chloride results in increased expression of CCDC102B mRNA CTD PMID:16870260 NCBI chr18:68,715,216...69,058,121
Ensembl chr18:68,715,209...69,055,189 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 increases expression EXP zinc chloride results in increased expression of CCL11 mRNA CTD PMID:19428942 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL15 C-C motif chemokine ligand 15 decreases expression EXP zinc chloride results in decreased expression of CCL15 mRNA CTD PMID:19428942 NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 decreases expression EXP zinc chloride results in decreased expression of CCL17 mRNA CTD PMID:19428942 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 decreases expression EXP zinc chloride results in decreased expression of CCL19 mRNA CTD PMID:19428942 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 increases expression EXP zinc chloride results in increased expression of CCL20 mRNA CTD PMID:19428942 PMID:21540303 PMID:27427241 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCL24 C-C motif chemokine ligand 24 decreases expression EXP zinc chloride results in decreased expression of CCL24 mRNA CTD PMID:19428942 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356 		JBrowse link
G CCL26 C-C motif chemokine ligand 26 increases expression EXP zinc chloride results in increased expression of CCL26 mRNA CTD PMID:19428942 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896 		JBrowse link
G CCNB1 cyclin B1 increases expression ISO zinc chloride results in increased expression of CCNB1 mRNA CTD PMID:19000923 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCNG1 cyclin G1 multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride results in increased expression of CCNG1 mRNA] CTD PMID:16842966 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151 		JBrowse link
G CCNG2 cyclin G2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CCNG2 mRNA] CTD PMID:22202117 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 decreases expression EXP zinc chloride results in decreased expression of CCR6 mRNA CTD PMID:19428942 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141 		JBrowse link
G CCR8 C-C motif chemokine receptor 8 decreases expression EXP zinc chloride results in decreased expression of CCR8 mRNA CTD PMID:19428942 NCBI chr 3:39,329,709...39,333,680
Ensembl chr 3:39,329,709...39,333,680 		JBrowse link
G CD86 CD86 molecule decreases expression ISO zinc chloride results in decreased expression of CD86 protein CTD PMID:24284788 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CD9 CD9 molecule increases expression EXP zinc chloride results in increased expression of CD9 mRNA CTD PMID:16870260 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271 		JBrowse link
G CDH17 cadherin 17 decreases expression EXP zinc chloride results in decreased expression of CDH17 mRNA CTD PMID:18947441 NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in increased expression of CDKN1A protein CTD PMID:16624386 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B decreases expression EXP zinc chloride results in decreased expression of CDKN1B mRNA CTD PMID:21540303 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B decreases expression EXP zinc chloride results in decreased expression of CDKN2B mRNA CTD PMID:21540303 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CDR1 cerebellar degeneration related 1 decreases expression EXP zinc chloride results in decreased expression of CDR1 mRNA CTD PMID:16870260 NCBI chr  X:140,772,083...140,793,212
Ensembl chr  X:140,783,578...140,784,366 		JBrowse link
G CEACAM6 CEA cell adhesion molecule 6 increases expression EXP zinc chloride results in increased expression of CEACAM6 mRNA CTD PMID:18947441 NCBI chr19:41,755,530...41,772,211
Ensembl chr19:41,750,977...41,772,211 		JBrowse link
G CFTR CF transmembrane conductance regulator increases expression EXP zinc chloride results in increased expression of CFTR mRNA CTD PMID:16870260 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CHEK1 checkpoint kinase 1 increases expression ISO zinc chloride results in increased expression of CHEK1 mRNA CTD PMID:19000923 NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CITED2 mRNA] CTD PMID:22202117 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of COL1A1 mRNA CTD PMID:19913120 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COMMD1 copper metabolism domain containing 1 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 NCBI chr 2:61,888,391...62,136,058
Ensembl chr 2:61,888,724...62,147,247 		JBrowse link
G COX17 cytochrome c oxidase copper chaperone COX17 decreases expression EXP zinc chloride results in decreased expression of COX17 mRNA CTD PMID:18947441 NCBI chr 3:119,663,975...119,677,406
Ensembl chr 3:119,654,513...119,677,454 		JBrowse link
G CP ceruloplasmin increases expression EXP zinc chloride results in increased expression of CP mRNA CTD PMID:18947441 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 increases expression EXP zinc chloride results in increased expression of CPS1 mRNA CTD PMID:16870260 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
G CRP C-reactive protein increases expression EXP zinc chloride results in increased expression of CRP mRNA CTD PMID:19428942 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF2 colony stimulating factor 2 increases expression
multiple interactions		 EXP
ISO		 zinc chloride results in increased expression of CSF2 mRNA
zinc chloride results in increased expression of CSF2 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]		 CTD PMID:18509044 PMID:21540303 PMID:27427241 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSRP2 cysteine and glycine rich protein 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CSRP2 mRNA] CTD PMID:22202117 NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases expression EXP zinc chloride results in increased expression of CXCL1 mRNA CTD PMID:19428942 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 increases expression EXP zinc chloride results in increased expression of CXCL11 mRNA CTD PMID:19428942 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL13 C-X-C motif chemokine ligand 13 decreases expression EXP zinc chloride results in decreased expression of CXCL13 mRNA CTD PMID:19428942 NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834 		JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 increases expression EXP zinc chloride results in increased expression of CXCL14 mRNA CTD PMID:19428942 NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 increases expression EXP zinc chloride results in increased expression of CXCL5 mRNA CTD PMID:19428942 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 decreases expression EXP zinc chloride results in decreased expression of CXCL6 mRNA CTD PMID:19428942 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions
increases secretion		 EXP zinc chloride results in increased expression of CXCL8 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; DUOX1 protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; pyrazolanthrone inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; Thiourea inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]		 CTD PMID:19428942 PMID:21540303 PMID:21842098 PMID:23692033 PMID:27427241 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases stability
multiple interactions		 ISO zinc chloride results in increased stability of CYP1A1 mRNA; zinc chloride results in increased stability of CYP1A1 protein
zinc chloride inhibits the reaction [1,10-phenanthroline inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]		 CTD PMID:19896525 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G DCP1B decapping mRNA 1B multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of DCP1B mRNA CTD PMID:22415087 NCBI chr12:1,941,591...2,004,457
Ensembl chr12:1,946,053...2,004,535 		JBrowse link
G DDX21 DExD-box helicase 21 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of DDX21 mRNA] CTD PMID:22202117 NCBI chr10:68,956,170...68,985,068
Ensembl chr10:68,956,135...68,985,068 		JBrowse link
G DENND2B DENN domain containing 2B increases expression EXP zinc chloride results in increased expression of DENND2B mRNA CTD PMID:16870260 NCBI chr11:8,693,352...8,910,951
Ensembl chr11:8,693,351...8,910,951 		JBrowse link
G DHRS2 dehydrogenase/reductase 2 increases expression EXP zinc chloride results in increased expression of DHRS2 mRNA CTD PMID:16870260 NCBI chr14:23,630,115...23,645,639
Ensembl chr14:23,630,115...23,645,639 		JBrowse link
G DICER1 dicer 1, ribonuclease III multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of DICER1 protein CTD PMID:22415087 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of DLL4 mRNA CTD PMID:31588059 NCBI chr15:40,929,340...40,939,073
Ensembl chr15:40,929,340...40,939,073 		JBrowse link
G DRD1 dopamine receptor D1 multiple interactions ISO zinc chloride inhibits the reaction [ecopipam binds to DRD1 protein]; zinc chloride inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9109525 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD2 dopamine receptor D2 multiple interactions ISO zinc chloride inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein] CTD PMID:9109525 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DROSHA drosha ribonuclease III multiple interactions EXP [Clioquinol co-treated with zinc chloride] affects the expression of DROSHA protein CTD PMID:22415087 NCBI chr 5:31,400,494...31,532,093
Ensembl chr 5:31,400,494...31,532,196 		JBrowse link
G DUOX1 dual oxidase 1 multiple interactions EXP DUOX1 protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein] CTD PMID:27427241 NCBI chr15:45,129,994...45,165,574
Ensembl chr15:45,129,933...45,165,576 		JBrowse link
G EGFR epidermal growth factor receptor increases phosphorylation EXP zinc chloride results in increased phosphorylation of EGFR protein CTD PMID:21540303 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EGLN1 mRNA]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein] CTD PMID:16579968 PMID:22202117 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G EIF4E eukaryotic translation initiation factor 4E multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E mRNA; [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E protein CTD PMID:22415087 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133 		JBrowse link
G ELK1 ETS transcription factor ELK1 multiple interactions
increases activity		 ISO zinc chloride results in increased phosphorylation of and results in increased activity of ELK1 protein
zinc chloride results in increased activity of ELK1 protein		 CTD PMID:16960431 PMID:20412391 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,521...47,650,604 		JBrowse link
G ENO2 enolase 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ENO2 mRNA] CTD PMID:22202117 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G EPO erythropoietin multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EPO protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA] CTD PMID:11090055 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G F2RL2 coagulation factor II thrombin receptor like 2 decreases expression EXP zinc chloride results in decreased expression of F2RL2 mRNA CTD PMID:16870260 NCBI chr 5:76,615,482...76,623,403
Ensembl chr 5:76,615,482...76,623,413 		JBrowse link
G FABP1 fatty acid binding protein 1 decreases expression EXP zinc chloride results in decreased expression of FABP1 mRNA CTD PMID:18947441 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062 		JBrowse link
G FAM162A family with sequence similarity 162 member A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of FAM162A mRNA] CTD PMID:22202117 NCBI chr 3:122,384,182...122,412,334
Ensembl chr 3:122,384,161...122,412,334 		JBrowse link
G FASN fatty acid synthase decreases expression EXP zinc chloride results in decreased expression of FASN mRNA CTD PMID:21540303 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of FOS mRNA] CTD PMID:22202117 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit increases expression ISO zinc chloride results in increased expression of FOSL1 mRNA CTD PMID:19000923 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G FOXA2 forkhead box A2 decreases expression EXP zinc chloride results in decreased expression of FOXA2 mRNA CTD PMID:21540303 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,580,998...22,585,455 		JBrowse link
G FOXD1 forkhead box D1 increases expression EXP zinc chloride results in increased expression of FOXD1 mRNA CTD PMID:16870260 NCBI chr 5:73,446,266...73,448,777
Ensembl chr 5:73,444,827...73,448,777 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of G6PC1 protein] CTD PMID:22413763 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein] CTD PMID:18972399 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP zinc chloride results in increased expression of GADD45A mRNA CTD PMID:33645215 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GBE1 1,4-alpha-glucan branching enzyme 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of GBE1 mRNA] CTD PMID:22202117 NCBI chr 3:81,489,703...81,761,645
Ensembl chr 3:81,489,703...81,761,645 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions
increases expression		 EXP zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLC mRNA]
zinc chloride results in increased expression of GCLC mRNA		 CTD PMID:18385089 PMID:33645215 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions EXP zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA] CTD PMID:18385089 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions ISO zinc chloride inhibits the reaction [Vincristine results in increased expression of GJA1 protein] CTD PMID:34286406 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GPX2 glutathione peroxidase 2 increases expression EXP zinc chloride results in increased expression of GPX2 mRNA CTD PMID:18947441 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 increases expression EXP zinc chloride results in increased expression of GRIK2 mRNA CTD PMID:16870260 NCBI chr 6:101,393,708...102,070,083
Ensembl chr 6:100,962,701...102,081,622 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of GRIN2A protein]; zinc chloride results in increased expression of and results in increased phosphorylation of GRIN2A protein CTD PMID:12211081 NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,182,928 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B multiple interactions ISO AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of GRIN2B protein]; zinc chloride results in increased expression of and results in increased phosphorylation of GRIN2B protein CTD PMID:12211081 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002 		JBrowse link
G GRM5 glutamate metabotropic receptor 5 multiple interactions
increases expression		 ISO Copper inhibits the reaction [zinc chloride results in increased expression of GRM5 protein] CTD PMID:25007851 NCBI chr11:88,504,642...89,065,982
Ensembl chr11:88,504,576...89,065,982 		JBrowse link
G GSR glutathione-disulfide reductase multiple interactions EXP
ISO		 [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to zinc chloride
zinc chloride inhibits the reaction [Cadmium Chloride results in increased activity of GSR protein]; zinc chloride inhibits the reaction [Copper results in decreased activity of GSR protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]		 CTD PMID:12632252 PMID:19429256 PMID:20600438 PMID:23726800 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions ISO [Cadmium Chloride co-treated with zinc chloride] results in increased expression of GSTP1 protein CTD PMID:15602745 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GYS1 glycogen synthase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of GYS1 mRNA] CTD PMID:22202117 NCBI chr19:48,968,130...48,993,309
Ensembl chr19:48,968,130...48,993,310 		JBrowse link
G H2AX H2A.X variant histone increases expression EXP zinc chloride results in increased expression of H2AX mRNA CTD PMID:18947441 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HCFC1R1 host cell factor C1 regulator 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HCFC1R1 mRNA] CTD PMID:22202117 NCBI chr16:3,022,620...3,024,286
Ensembl chr16:3,022,625...3,024,286 		JBrowse link
G HDAC1 histone deacetylase 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of HDAC1 mRNA CTD PMID:31588059 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HELLS helicase, lymphoid specific increases expression ISO zinc chloride results in increased expression of HELLS mRNA CTD PMID:19000923 NCBI chr10:94,545,788...94,613,905
Ensembl chr10:94,545,329...94,613,905 		JBrowse link
G HEPH hephaestin decreases expression EXP zinc chloride results in decreased expression of HEPH mRNA CTD PMID:18947441 NCBI chr  X:66,162,671...66,268,863
Ensembl chr  X:66,162,671...66,268,867 		JBrowse link
G HEXB hexosaminidase subunit beta multiple interactions ISO zinc chloride inhibits the reaction [2-phenylphenol results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [bitertanol results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Butylated Hydroxyanisole results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Butylated Hydroxytoluene results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [butylparaben results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [EPN oxon results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Permethrin results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [prothiophos results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [pyridaben results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [salinomycin results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [terbufos results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
affects splicing
increases expression		 EXP
ISO		 Cycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form]; zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]; zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
zinc chloride affects the splicing of HIF1A mRNA
zinc chloride results in increased expression of HIF1A mRNA; zinc chloride results in increased expression of HIF1A mRNA alternative form; zinc chloride results in increased expression of HIF1A protein alternative form
[Doxorubicin co-treated with zinc chloride] results in decreased expression of HIF1A mRNA		 CTD PMID:11090055 PMID:11739637 PMID:16579968 PMID:19714248 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HILPDA hypoxia inducible lipid droplet associated multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HILPDA mRNA] CTD PMID:22202117 NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 multiple interactions EXP
ISO		 zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of HIPK2 protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in decreased expression of HIPK2 protein]
[Doxorubicin co-treated with zinc chloride] results in increased expression of HIPK2 mRNA		 CTD PMID:19714248 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998 		JBrowse link
G HK2 hexokinase 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HK2 mRNA] CTD PMID:22202117 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions		 EXP
ISO		 zinc chloride results in increased expression of HMOX1 mRNA; zinc chloride results in increased expression of HMOX1 protein
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HMOX1 mRNA]
HMOX1 enhancer affects the reaction [zinc chloride results in increased expression of HMOX1 mRNA]		 CTD PMID:7538129 PMID:16870260 PMID:22202117 PMID:27427241 PMID:33645215 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSP90AA2P heat shock protein 90 alpha family class A member 2, pseudogene increases expression EXP zinc chloride results in increased expression of HSP90AA2P mRNA CTD PMID:21540303 NCBI chr11:27,888,171...27,891,092
Ensembl chr11:27,888,838...27,891,033 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression EXP
ISO		 zinc chloride results in increased expression of HSPA1A mRNA CTD PMID:12085988 PMID:16870260 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression ISO zinc chloride results in increased expression of HSPA1B mRNA CTD PMID:12085988 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP zinc chloride results in increased expression of HSPA6 mRNA CTD PMID:16870260 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 increases expression ISO zinc chloride results in increased expression of HSPD1 protein CTD PMID:19429256 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IFNA2 interferon alpha 2 decreases expression EXP zinc chloride results in decreased expression of IFNA2 mRNA CTD PMID:19428942 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IFNG interferon gamma multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of IFNG mRNA; zinc chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 PMID:31588059 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta decreases expression EXP zinc chloride results in decreased expression of IKBKB mRNA CTD PMID:21540303 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL10 interleukin 10 increases expression ISO zinc chloride results in increased expression of IL10 mRNA CTD PMID:24284788 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL10RB interleukin 10 receptor subunit beta decreases expression EXP zinc chloride results in decreased expression of IL10RB mRNA CTD PMID:19428942 NCBI chr21:33,266,367...33,310,182
Ensembl chr21:33,266,367...33,311,420 		JBrowse link
G IL12B interleukin 12B decreases expression ISO zinc chloride results in decreased expression of IL12B mRNA CTD PMID:24284788 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL18R1 interleukin 18 receptor 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of IL18R1 mRNA] CTD PMID:22202117 NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777 		JBrowse link
G IL1A interleukin 1 alpha increases expression
multiple interactions		 ISO zinc chloride results in increased expression of IL1A protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]		 CTD PMID:18509044 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression		 ISO
EXP		 N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
zinc chloride inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
zinc chloride results in increased expression of IL1B mRNA		 CTD PMID:9138684 PMID:18509044 PMID:19130485 PMID:27427241 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 increases expression ISO zinc chloride results in increased expression of IL1RL1 mRNA CTD PMID:19000923 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL1RN interleukin 1 receptor antagonist increases expression EXP zinc chloride results in increased expression of IL1RN mRNA CTD PMID:19428942 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL3 interleukin 3 multiple interactions
increases expression		 ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein] CTD PMID:18509044 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL36RN interleukin 36 receptor antagonist decreases expression EXP zinc chloride results in decreased expression of IL36RN mRNA CTD PMID:19428942 NCBI chr 2:113,058,638...113,064,744
Ensembl chr 2:113,058,638...113,065,382 		JBrowse link
G IL37 interleukin 37 decreases expression EXP zinc chloride results in decreased expression of IL37 mRNA CTD PMID:19428942 NCBI chr 2:112,911,165...112,918,882
Ensembl chr 2:112,911,165...112,918,882 		JBrowse link
G IL6 interleukin 6 increases secretion
multiple interactions
increases expression		 EXP zinc chloride results in increased secretion of IL6 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of IL6 protein]; Thiourea inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]
zinc chloride results in increased expression of IL6 mRNA		 CTD PMID:21842098 PMID:27427241 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INSIG2 insulin induced gene 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of INSIG2 mRNA] CTD PMID:22202117 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997 		JBrowse link
G INSR insulin receptor increases phosphorylation ISO zinc chloride results in increased phosphorylation of INSR protein CTD PMID:11340092 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G IREB2 iron responsive element binding protein 2 increases expression EXP zinc chloride results in increased expression of IREB2 mRNA CTD PMID:18947441 NCBI chr15:78,437,431...78,501,453
Ensembl chr15:78,437,431...78,501,453 		JBrowse link
G ITGB6 integrin subunit beta 6 increases expression EXP zinc chloride results in increased expression of ITGB6 mRNA CTD PMID:16870260 NCBI chr 2:160,099,671...160,200,272
Ensembl chr 2:160,099,667...160,200,313 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP
ISO		 zinc chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [zinc chloride results in increased expression of JUN mRNA]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]		 CTD PMID:11306679 PMID:19000923 PMID:21540303 PMID:30768131 PMID:33645215 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO zinc chloride results in increased expression of JUNB mRNA CTD PMID:19000923 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KAT5 lysine acetyltransferase 5 multiple interactions EXP zinc chloride affects the reaction [4-aminophenylarsenoxide binds to KAT5 protein] CTD PMID:28837777 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604 		JBrowse link
G KDM3A lysine demethylase 3A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of KDM3A mRNA] CTD PMID:22202117 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716 		JBrowse link
G KDM4B lysine demethylase 4B multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of KDM4B mRNA] CTD PMID:22202117 NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,598 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 affects folding
multiple interactions		 ISO zinc chloride affects the folding of KEAP1 protein
zinc chloride promotes the reaction [KEAP1 protein binds to KEAP1 protein]		 CTD PMID:30261176 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KIF5A kinesin family member 5A multiple interactions
decreases activity		 EXP Adenosine Triphosphate inhibits the reaction [zinc chloride results in decreased activity of KIF5A protein]; Magnesium Chloride affects the reaction [zinc chloride results in decreased activity of KIF5A protein] CTD PMID:28122263 NCBI chr12:57,550,044...57,586,633
Ensembl chr12:57,546,026...57,586,633 		JBrowse link
G LEP leptin increases expression EXP zinc chloride results in increased expression of LEP mRNA CTD PMID:21540303 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LIMCH1 LIM and calponin homology domains 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of LIMCH1 mRNA] CTD PMID:22202117 NCBI chr 4:41,359,607...41,700,044
Ensembl chr 4:41,359,607...41,700,044 		JBrowse link
G LTA lymphotoxin alpha decreases expression
increases expression		 EXP zinc chloride results in decreased expression of LTA mRNA
zinc chloride results in increased expression of LTA mRNA		 CTD PMID:19428942 PMID:21540303 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G LTB4R leukotriene B4 receptor decreases expression EXP zinc chloride results in decreased expression of LTB4R mRNA CTD PMID:19428942 NCBI chr14:24,311,502...24,318,036
Ensembl chr14:24,311,450...24,318,036 		JBrowse link
G MAFF MAF bZIP transcription factor F multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of MAFF mRNA] CTD PMID:22202117 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507 		JBrowse link
G MAFG MAF bZIP transcription factor G increases expression EXP zinc chloride results in increased expression of MAFG mRNA CTD PMID:11162468 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735 		JBrowse link
G MAML1 mastermind like transcriptional coactivator 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of MAML1 mRNA CTD PMID:31588059 NCBI chr 5:179,732,822...179,777,283
Ensembl chr 5:179,732,822...179,777,283 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 increases activity ISO zinc chloride results in increased activity of MAP2K4 protein CTD PMID:11306679 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 multiple interactions
increases activity		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAP3K1 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAP3K1 protein] CTD PMID:11306679 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation		 ISO N,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein
zinc chloride results in increased activity of MAPK1 protein		 CTD PMID:11306679 PMID:11551972 PMID:16960431 PMID:20412391 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; N,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; Vanadates promotes the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16960431 PMID:20412391 PMID:21575692 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]; [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; Acetylcysteine inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]; RAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]; zinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:11306679 PMID:20423716 PMID:30768131 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO zinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK9 protein] CTD PMID:20423716 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 increases expression ISO zinc chloride results in increased expression of MCM3 mRNA CTD PMID:19000923 NCBI chr 6:52,264,015...52,284,742
Ensembl chr 6:52,264,014...52,284,881 		JBrowse link
G MIF macrophage migration inhibitory factor decreases expression EXP zinc chloride results in decreased expression of MIF mRNA CTD PMID:18947441 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR130A microRNA 130a multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR130A mRNA CTD PMID:22415087 NCBI chr11:57,641,198...57,641,286
Ensembl chr11:57,641,198...57,641,286 		JBrowse link
G MIR15A microRNA 15a multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR15A mRNA CTD PMID:22415087 NCBI chr13:50,049,119...50,049,201
Ensembl chr13:50,049,119...50,049,201 		JBrowse link
G MIR223 microRNA 223 multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR223 mRNA CTD PMID:22415087 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979 		JBrowse link
G MIR29A microRNA 29a multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR29A mRNA CTD PMID:22415087 NCBI chr 7:130,876,747...130,876,810
Ensembl chr 7:130,876,747...130,876,810 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein] CTD PMID:21573219 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP7 matrix metallopeptidase 7 decreases expression EXP zinc chloride results in decreased expression of MMP7 mRNA CTD PMID:21540303 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MT1A metallothionein 1A increases expression
multiple interactions		 ISO zinc chloride results in increased expression of MT1A mRNA; zinc chloride results in increased expression of MT1A protein
zinc chloride promotes the reaction [Glucose results in increased expression of MT1A mRNA]		 CTD PMID:8928928 PMID:17637929 PMID:23056475 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087 		JBrowse link
G MT1E metallothionein 1E increases expression EXP zinc chloride results in increased expression of MT1E mRNA CTD PMID:16870260 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112 		JBrowse link
G MT1F metallothionein 1F increases expression EXP zinc chloride results in increased expression of MT1F mRNA CTD PMID:16870260 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698 		JBrowse link
G MT1G metallothionein 1G increases expression EXP zinc chloride results in increased expression of MT1G mRNA CTD PMID:16870260 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065 		JBrowse link
G MT1H metallothionein 1H increases expression EXP zinc chloride results in increased expression of MT1H mRNA CTD PMID:16870260 PMID:18947441 NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129 		JBrowse link
G MT1HL1 metallothionein 1H like 1 increases expression EXP zinc chloride results in increased expression of MT1HL1 mRNA CTD PMID:16870260 NCBI chr 1:237,004,103...237,004,441
Ensembl chr 1:237,004,103...237,004,441 		JBrowse link
G MT1L metallothionein 1L, pseudogene increases expression EXP zinc chloride results in increased expression of MT1L mRNA CTD PMID:16870260 NCBI chr16:56,617,461...56,618,818
Ensembl chr16:56,617,563...56,618,680 		JBrowse link
G MT1M metallothionein 1M increases expression EXP zinc chloride results in increased expression of MT1M mRNA CTD PMID:16870260 NCBI chr16:56,632,659...56,633,981
Ensembl chr16:56,632,659...56,633,981 		JBrowse link
G MT1X metallothionein 1X multiple interactions
increases expression
affects response to substance
decreases expression
affects binding		 EXP
ISO		 epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of MT1X mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [zinc chloride results in increased expression of MT1X mRNA]
zinc chloride results in increased expression of MT1 mRNA; zinc chloride results in increased expression of MT1 protein
MT1 affects the susceptibility to zinc chloride
zinc chloride results in decreased expression of MT1 protein
zinc chloride binds to MT1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; bisindolylmaleimide I inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Dicumarol inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]; Genistein inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Ro 31-8220 inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Sodium Selenite inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Wortmannin inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]		 CTD PMID:3422486 PMID:11551972 PMID:14998373 PMID:15288509 PMID:16870260 More... NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MT2A metallothionein 2A multiple interactions
increases expression
affects binding
affects response to substance		 EXP
ISO		 [zinc chloride co-treated with pyrithione zinc] results in increased expression of MT2A mRNA; Dactinomycin inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; zinc chloride inhibits the reaction [Lipopolysaccharides results in increased expression of MT2A mRNA]
zinc chloride results in increased expression of MT2A mRNA; zinc chloride results in increased expression of MT2A protein
zinc chloride promotes the reaction [Glucose results in increased expression of MT2A mRNA]
zinc chloride results in increased expression of MT2 mRNA; zinc chloride results in increased expression of MT2 protein
zinc chloride promotes the reaction [Cadmium Chloride results in increased expression of MT2 mRNA]
zinc chloride binds to MT2 protein
MT2 affects the susceptibility to zinc chloride		 CTD PMID:9138684 PMID:15288509 PMID:16842966 PMID:16870260 PMID:16987576 More... NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MT3 metallothionein 3 increases expression EXP zinc chloride results in increased expression of MT3 mRNA CTD PMID:18947441 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088 		JBrowse link
G MTA2 metastasis associated 1 family member 2 decreases expression EXP zinc chloride results in decreased expression of MTA2 mRNA CTD PMID:16870260 NCBI chr11:62,593,214...62,601,865
Ensembl chr11:62,593,214...62,601,865 		JBrowse link
G MTF1 metal regulatory transcription factor 1 multiple interactions
affects localization
decreases expression		 ISO
EXP		 zinc chloride results in increased phosphorylation of and results in increased activity of MTF1 protein
zinc chloride affects the localization of MTF1 protein
zinc chloride results in decreased expression of MTF1 mRNA		 CTD PMID:11551972 PMID:16423564 PMID:18947441 NCBI chr 1:37,809,574...37,859,592
Ensembl chr 1:37,809,574...37,859,592 		JBrowse link
G MTF2 metal response element binding transcription factor 2 decreases expression EXP zinc chloride results in decreased expression of MTF2 mRNA CTD PMID:18947441 NCBI chr 1:93,079,283...93,139,076
Ensembl chr 1:93,079,235...93,139,079 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 multiple interactions
increases response to substance		 ISO NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]
NCF1 results in increased susceptibility to zinc chloride		 CTD PMID:18509044 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NDRG1 N-myc downstream regulated 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of NDRG1 mRNA] CTD PMID:22202117 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022 		JBrowse link
G NDUFAF5 NADH:ubiquinone oxidoreductase complex assembly factor 5 decreases expression EXP zinc chloride results in decreased expression of NDUFAF5 mRNA CTD PMID:16870260 NCBI chr20:13,785,028...13,821,580
Ensembl chr20:13,785,007...13,821,580 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor decreases expression EXP zinc chloride results in decreased expression of NF2 mRNA CTD PMID:16870260 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects response to substance
multiple interactions		 ISO
EXP		 [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to zinc chloride
zinc chloride promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]		 CTD PMID:18385089 PMID:19303893 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 increases activity EXP zinc chloride results in increased activity of NFKB1 protein CTD PMID:21842098 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NIP7 nucleolar pre-rRNA processing protein NIP7 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of NIP7 mRNA] CTD PMID:22202117 NCBI chr16:69,339,772...69,343,106
Ensembl chr16:69,337,996...69,343,106 		JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of NMNAT1 mRNA CTD PMID:31588059 NCBI chr 1:9,942,923...9,996,892
Ensembl chr 1:9,943,428...9,985,501 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO zinc chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOX4 NADPH oxidase 4 increases expression EXP zinc chloride results in increased expression of NOX4 mRNA CTD PMID:16870260 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NTN3 netrin 3 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of NTN3 mRNA CTD PMID:31588059 NCBI chr16:2,471,297...2,474,145
Ensembl chr16:2,471,297...2,474,145 		JBrowse link
G OR2AG2 olfactory receptor family 2 subfamily AG member 2 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of OR2AG2 mRNA CTD PMID:31588059 NCBI chr11:6,765,626...6,771,976
Ensembl chr11:6,765,626...6,771,976 		JBrowse link
G OR4C12 olfactory receptor family 4 subfamily C member 12 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OR4C12 mRNA CTD PMID:31588059 NCBI chr11:49,981,473...49,982,535
Ensembl chr11:49,981,473...49,982,535 		JBrowse link
G ORM1 orosomucoid 1 increases expression ISO zinc chloride results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479 		JBrowse link
G ORM2 orosomucoid 2 increases expression ISO zinc chloride results in increased expression of ORM2 mRNA CTD PMID:19000923 NCBI chr 9:114,329,869...114,333,251
Ensembl chr 9:114,329,869...114,333,251 		JBrowse link
G P2RX2 purinergic receptor P2X 2 multiple interactions ISO zinc chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr12:132,618,776...132,622,388
Ensembl chr12:132,618,776...132,622,388 		JBrowse link
G P4HA1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of P4HA1 mRNA] CTD PMID:22202117 NCBI chr10:73,007,217...73,096,866
Ensembl chr10:73,007,217...73,096,974 		JBrowse link
G P4HA2 prolyl 4-hydroxylase subunit alpha 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of P4HA2 mRNA] CTD PMID:22202117 NCBI chr 5:132,190,147...132,227,853
Ensembl chr 5:132,190,147...132,295,315 		JBrowse link
G PAIP1 poly(A) binding protein interacting protein 1 decreases expression EXP zinc chloride results in decreased expression of PAIP1 mRNA CTD PMID:18947441 NCBI chr 5:43,526,267...43,557,411
Ensembl chr 5:43,526,267...43,557,758 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases expression
increases activity
increases response to substance		 EXP
ISO		 zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]; zinc chloride inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]; zinc chloride promotes the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]
zinc chloride results in increased expression of PARP1 protein
zinc chloride results in increased activity of PARP1 protein
PARP1 results in increased susceptibility to zinc chloride
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; Cibacron Blue F 3GA inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; coomassie Brilliant Blue inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; periodate-oxidized adenosine 5'-triphosphate inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]		 CTD PMID:18509044 PMID:19056730 PMID:19714248 PMID:22253048 PMID:33645215 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 increases expression EXP zinc chloride results in increased expression of PCBD1 mRNA CTD PMID:18947441 NCBI chr10:70,882,280...70,888,565
Ensembl chr10:70,882,280...70,888,565 		JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO [Cadmium Chloride co-treated with zinc chloride] results in increased expression of PCNA protein CTD PMID:15602745 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PDAP1 PDGFA associated protein 1 multiple interactions ISO zinc chloride promotes the reaction [Cadmium Chloride results in increased expression of PDAP1 mRNA] CTD PMID:16842966 NCBI chr 7:99,394,673...99,408,597
Ensembl chr 7:99,392,048...99,408,597 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] CTD PMID:22202117 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669 		JBrowse link
G PEG3 paternally expressed 3 decreases expression EXP zinc chloride results in decreased expression of PEG3 mRNA CTD PMID:16870260 NCBI chr19:56,810,082...56,840,726
Ensembl chr19:56,810,077...56,840,728 		JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB3 mRNA] CTD PMID:22202117 NCBI chr10:6,144,921...6,326,637
Ensembl chr10:6,144,934...6,254,644 		JBrowse link
G PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB4 mRNA] CTD PMID:22202117 NCBI chr 3:48,517,684...48,563,136
Ensembl chr 3:48,517,684...48,562,015 		JBrowse link
G PGF placental growth factor increases expression EXP zinc chloride results in increased expression of PGF mRNA CTD PMID:16870260 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PGK1 phosphoglycerate kinase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PGK1 mRNA] CTD PMID:22202117 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295 		JBrowse link
G PGM1 phosphoglucomutase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PGM1 mRNA] CTD PMID:22202117 NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked increases expression ISO zinc chloride results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:22,032,325...22,251,310
Ensembl chr  X:22,032,325...22,494,713 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma multiple interactions ISO PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAP3K1 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 increases expression EXP zinc chloride results in increased expression of PIK3R4 mRNA CTD PMID:16870260 NCBI chr 3:130,678,934...130,746,829
Ensembl chr 3:130,678,934...130,746,829 		JBrowse link
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 increases expression ISO zinc chloride results in increased expression of PIK3R5 mRNA CTD PMID:19000923 NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,712 		JBrowse link
G PMP22 peripheral myelin protein 22 increases expression EXP zinc chloride results in increased expression of PMP22 mRNA CTD PMID:18947441 NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292 		JBrowse link
G PRKCA protein kinase C alpha multiple interactions
affects localization		 ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]; 1,3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of PRKCA protein]; Glucose promotes the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]; Vanadates promotes the reaction [zinc chloride affects the localization of PRKCA protein]; zinc chloride affects the localization of and results in increased activity of PRKCA protein CTD PMID:20800666 PMID:21575692 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PTH1R parathyroid hormone 1 receptor multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of PTH1R mRNA CTD PMID:19913120 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799 		JBrowse link
G RAB20 RAB20, member RAS oncogene family multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RAB20 mRNA] CTD PMID:22202117 NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722 		JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions ISO RAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RAD21 RAD21 cohesin complex component increases expression ISO zinc chloride results in increased expression of RAD21 mRNA CTD PMID:19000923 NCBI chr 8:116,845,934...116,874,776
Ensembl chr 8:116,845,934...116,874,776 		JBrowse link
G RAD51AP1 RAD51 associated protein 1 increases expression ISO zinc chloride results in increased expression of RAD51AP1 mRNA CTD PMID:19000923 NCBI chr12:4,538,890...4,560,047
Ensembl chr12:4,538,798...4,560,047 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions
increases phosphorylation		 ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein] CTD PMID:21575692 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RANGAP1 Ran GTPase activating protein 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RANGAP1 mRNA] CTD PMID:22202117 NCBI chr22:41,244,779...41,302,369
Ensembl chr22:41,244,779...41,286,187 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RBPJ mRNA] CTD PMID:22202117 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131 		JBrowse link
G RECK reversion inducing cysteine rich protein with kazal motifs multiple interactions EXP zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein] CTD PMID:21573219 NCBI chr 9:36,036,913...36,124,455
Ensembl chr 9:36,036,913...36,124,455 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation		 EXP RELA protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of IL6 protein]
zinc chloride results in increased phosphorylation of RELA protein		 CTD PMID:27427241 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIF1 replication timing regulatory factor 1 increases expression ISO zinc chloride results in increased expression of RIF1 mRNA CTD PMID:19000923 NCBI chr 2:151,409,902...151,534,435
Ensembl chr 2:151,409,883...151,508,013 		JBrowse link
G RIOK3 RIO kinase 3 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RIOK3 mRNA] CTD PMID:22202117 NCBI chr18:23,453,287...23,483,140
Ensembl chr18:23,453,287...23,486,603 		JBrowse link
G RORA RAR related orphan receptor A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RORA mRNA] CTD PMID:22202117 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302 		JBrowse link
G RPL11 ribosomal protein L11 decreases expression EXP zinc chloride results in decreased expression of RPL11 mRNA CTD PMID:18947441 NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835 		JBrowse link
G RRP15 ribosomal RNA processing 15 homolog multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRP15 mRNA] CTD PMID:22202117 NCBI chr 1:218,285,293...218,337,983
Ensembl chr 1:218,285,293...218,337,983 		JBrowse link
G RRS1 ribosome biogenesis regulator 1 homolog multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRS1 mRNA] CTD PMID:22202117 NCBI chr 8:66,429,014...66,430,733
Ensembl chr 8:66,429,014...66,430,733 		JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of RUNX2 protein; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 protein CTD PMID:19913120 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RUVBL1 mRNA] CTD PMID:22202117 NCBI chr 3:128,064,785...128,153,914
Ensembl chr 3:128,064,778...128,153,914 		JBrowse link
G SALL1 spalt like transcription factor 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of SALL1 mRNA CTD PMID:31588059 NCBI chr16:51,135,982...51,152,334
Ensembl chr16:51,135,982...51,152,334 		JBrowse link
G SAP30 Sin3A associated protein 30 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SAP30 mRNA] CTD PMID:22202117 NCBI chr 4:173,370,954...173,377,532
Ensembl chr 4:173,369,969...173,377,532 		JBrowse link
G SBNO1 strawberry notch homolog 1 increases expression EXP zinc chloride results in increased expression of SBNO1 mRNA CTD PMID:16870260 NCBI chr12:123,289,109...123,364,847
Ensembl chr12:123,289,109...123,364,847 		JBrowse link
G SCARA3 scavenger receptor class A member 3 decreases expression EXP zinc chloride results in decreased expression of SCARA3 mRNA CTD PMID:16870260 NCBI chr 8:27,633,463...27,734,141
Ensembl chr 8:27,633,868...27,676,776 		JBrowse link
G SCARB1 scavenger receptor class B member 1 increases expression ISO zinc chloride results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
G SCD stearoyl-CoA desaturase multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SCD mRNA] CTD PMID:22202117 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SELPLG selectin P ligand increases expression EXP zinc chloride results in increased expression of SELPLG mRNA CTD PMID:21540303 NCBI chr12:108,621,895...108,633,894
Ensembl chr12:108,621,895...108,633,894 		JBrowse link
G SERTAD2 SERTA domain containing 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SERTAD2 mRNA] CTD PMID:22202117 NCBI chr 2:64,631,621...64,653,913
Ensembl chr 2:64,631,621...64,751,005 		JBrowse link
G SHANK2 SH3 and multiple ankyrin repeat domains 2 multiple interactions
increases expression		 ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK2 protein] CTD PMID:25007851 NCBI chr11:70,467,854...71,253,228
Ensembl chr11:70,467,854...71,252,577 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 multiple interactions
increases expression		 ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK3 protein] CTD PMID:25007851 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,212 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 increases transport EXP SLC11A2 protein results in increased transport of zinc chloride CTD PMID:22736759 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566 		JBrowse link
G SLC16A3 solute carrier family 16 member 3 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SLC16A3 mRNA] CTD PMID:22202117 NCBI chr17:82,217,934...82,240,086
Ensembl chr17:82,217,934...82,261,129 		JBrowse link
G SLC1A2 solute carrier family 1 member 2 multiple interactions ISO [Kainic Acid co-treated with zinc chloride] results in decreased expression of SLC1A2 protein CTD PMID:19061913 NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 decreases expression EXP zinc chloride results in decreased expression of SLC1A5 mRNA CTD PMID:18947441 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594 		JBrowse link
G SLC25A15 solute carrier family 25 member 15 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of SLC25A15 mRNA] CTD PMID:22202117 NCBI chr13:40,789,611...40,812,460
Ensembl chr13:40,789,412...40,812,460 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions
increases expression		 EXP
ISO		 zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SLC2A1 mRNA]
zinc chloride results in increased expression of SLC2A1 mRNA		 CTD PMID:19000923 PMID:22202117 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC30A1 solute carrier family 30 member 1 multiple interactions
increases expression		 EXP
ISO		 epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of SLC30A1 mRNA]; zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in decreased expression of SLC30A1 mRNA]
zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A1 mRNA]; zinc chloride promotes the reaction [Glucose results in increased expression of SLC30A1 mRNA]		 CTD PMID:18947441 PMID:20392624 PMID:20471814 PMID:23056475 PMID:25653005 More... NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161 		JBrowse link
G SLC30A2 solute carrier family 30 member 2 increases expression
multiple interactions		 ISO zinc chloride results in increased expression of SLC30A2 mRNA
zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A2 mRNA]		 CTD PMID:20392624 PMID:25653005 NCBI chr 1:26,037,252...26,046,118
Ensembl chr 1:26,037,252...26,046,118 		JBrowse link
G SLC30A4 solute carrier family 30 member 4 multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A4 mRNA] CTD PMID:25653005 NCBI chr15:45,479,606...45,522,755
Ensembl chr15:45,479,606...45,522,755 		JBrowse link
G SLC30A5 solute carrier family 30 member 5 decreases expression
multiple interactions		 EXP zinc chloride results in decreased expression of SLC30A5 mRNA
Dactinomycin inhibits the reaction [zinc chloride results in decreased expression of SLC30A5 mRNA]		 CTD PMID:17234632 PMID:20392624 NCBI chr 5:69,094,014...69,131,069
Ensembl chr 5:69,093,991...69,131,069 		JBrowse link
G SLC30A7 solute carrier family 30 member 7 increases expression
decreases expression		 EXP zinc chloride results in increased expression of SLC30A7 mRNA
zinc chloride results in decreased expression of SLC30A7 mRNA		 CTD PMID:20392624 NCBI chr 1:100,896,090...100,996,078
Ensembl chr 1:100,896,076...100,981,757 		JBrowse link
G SLC31A2 solute carrier family 31 member 2 increases expression
decreases expression		 EXP zinc chloride results in increased expression of SLC31A2 mRNA
zinc chloride results in decreased expression of SLC31A2 mRNA		 CTD PMID:18947441 NCBI chr 9:113,151,007...113,164,140
Ensembl chr 9:113,150,976...113,164,140 		JBrowse link
G SLC39A1 solute carrier family 39 member 1 multiple interactions EXP zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A1 mRNA] CTD PMID:20471814 NCBI chr 1:153,959,110...153,968,184
Ensembl chr 1:153,959,099...153,968,184 		JBrowse link
G SLC39A2 solute carrier family 39 member 2 multiple interactions
increases expression		 EXP [SLC39A2 protein co-treated with zinc chloride] results in increased abundance of Glutathione; zinc chloride promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]; zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLC mRNA]; zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA]
zinc chloride results in increased expression of SLC39A2 mRNA		 CTD PMID:18385089 NCBI chr14:20,999,293...21,001,871
Ensembl chr14:20,999,255...21,001,871 		JBrowse link
G SLC39A3 solute carrier family 39 member 3 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A3 mRNA] CTD PMID:25653005 NCBI chr19:2,732,524...2,740,076
Ensembl chr19:2,732,204...2,740,028 		JBrowse link
G SLC39A4 solute carrier family 39 member 4 multiple interactions
decreases expression		 EXP
ISO		 zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A4 mRNA]
zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A4 mRNA]
zinc chloride results in decreased expression of SLC39A4 mRNA		 CTD PMID:20471814 PMID:25653005 NCBI chr 8:144,412,414...144,416,844
Ensembl chr 8:144,409,742...144,416,844 		JBrowse link
G SLC39A8 solute carrier family 39 member 8 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A8 mRNA] CTD PMID:25653005 NCBI chr 4:102,251,041...102,345,482
Ensembl chr 4:102,251,080...102,431,258 		JBrowse link
G SLC48A1 solute carrier family 48 member 1 increases expression EXP zinc chloride results in increased expression of SLC48A1 mRNA CTD PMID:16870260 NCBI chr12:47,753,934...47,782,751
Ensembl chr12:47,753,916...47,782,751 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A1 mRNA] CTD PMID:20060848 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SLC5A2 solute carrier family 5 member 2 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP110 protein binds to and affects the expression of SLC5A2 promoter]]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A2 mRNA] CTD PMID:20060848 NCBI chr16:31,483,123...31,490,769
Ensembl chr16:31,483,002...31,490,860 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 increases expression EXP zinc chloride results in increased expression of SLC9A1 mRNA CTD PMID:18947441 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981 		JBrowse link
G SORD sorbitol dehydrogenase multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of SORD protein] CTD PMID:18972399 NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185 		JBrowse link
G SP1 Sp1 transcription factor multiple interactions
increases activity		 ISO
EXP		 zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]]
zinc chloride results in increased activity of SP1 protein		 CTD PMID:9330853 PMID:20060848 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SP110 SP110 nuclear body protein multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP110 protein binds to and affects the expression of SLC5A2 promoter]] CTD PMID:20060848 NCBI chr 2:230,165,186...230,225,636
Ensembl chr 2:230,165,186...230,225,729 		JBrowse link
G