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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 5.3.* (intramolecular oxidoreductase) inhibitor
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Accession:CHEBI:76694 term browser browse the term
Definition:An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*).
Synonyms:related_synonym: EC 5.3.* (intramolecular oxidoreductase) inhibitors;   intramolecular oxidoreductase inhibitor;   intramolecular oxidoreductase inhibitors


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amorolfine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA] CTD PMID:23688403 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA]; amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 protein] CTD PMID:24471457 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Il4 interleukin 4 multiple interactions ISO 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; amorolfine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone] CTD PMID:23688403 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO amorolfine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein] CTD PMID:23688403 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO amorolfine inhibits the reaction [Biological Products results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:24471457 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein] CTD PMID:23688403 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
copper(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase decreases expression ISO cupric chloride results in decreased expression of AASDHPPT mRNA CTD PMID:17211630 NCBI chr 8:1,432,757...1,450,175
Ensembl chr 8:1,439,340...1,450,138
JBrowse link
G Abcf3 ATP binding cassette subfamily F member 3 increases expression ISO cupric chloride results in increased expression of ABCF3 mRNA CTD PMID:17211630 NCBI chr11:84,026,206...84,037,938
Ensembl chr11:84,026,207...84,037,938
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO cupric chloride results in increased expression of ABHD4 mRNA CTD PMID:17211630 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP cupric chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ACHE protein] CTD PMID:24799335 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Aco1 aconitase 1 decreases expression ISO cupric chloride results in decreased expression of ACO1 protein CTD PMID:29617964 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Actb actin, beta increases expression ISO cupric chloride results in increased expression of ACTB protein CTD PMID:29617964 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Adrm1 adhesion regulating molecule 1 increases expression ISO cupric chloride results in increased expression of ADRM1 mRNA CTD PMID:17211630 NCBI chr 3:175,548,181...175,552,943
Ensembl chr 3:175,548,174...175,552,947
JBrowse link
G Ahsg alpha-2-HS-glycoprotein decreases expression ISO cupric chloride results in decreased expression of AHSG mRNA CTD PMID:17211630 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression ISO cupric chloride results in increased expression of AKR1A1 protein CTD PMID:29617964 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Alb albumin multiple interactions ISO ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein] CTD PMID:11820775 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases expression ISO cupric chloride results in increased expression of ALDH1L1 mRNA CTD PMID:17211630 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO cupric chloride results in increased expression of ALDOA mRNA
cupric chloride results in increased expression of ALDOA protein
CTD PMID:17211630, PMID:29617964 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO cupric chloride results in decreased expression of ALDOC protein CTD PMID:29617964 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase decreases activity ISO cupric chloride results in decreased activity of ALKBH2 protein CTD PMID:28926697 NCBI chr12:48,257,575...48,262,244
Ensembl chr12:48,257,609...48,262,243
JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase decreases activity ISO cupric chloride results in decreased activity of ALKBH3 protein CTD PMID:28926697 NCBI chr 3:82,874,242...82,907,467
Ensembl chr 3:82,874,248...82,906,581
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO cupric chloride results in increased expression of ANKRD1 mRNA CTD PMID:17211630 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression ISO cupric chloride results in decreased expression of ANPEP mRNA CTD PMID:17211630 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Apom apolipoprotein M increases expression ISO cupric chloride results in increased expression of APOM mRNA CTD PMID:17211630 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G App amyloid beta precursor protein increases expression
multiple interactions
EXP
ISO
cupric chloride results in increased expression of APP mRNA; cupric chloride results in increased expression of APP protein
cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form; PP242 inhibits the reaction [cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form]
CTD PMID:22542740, PMID:32512069 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor multiple interactions ISO [Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein CTD PMID:19789329 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein] CTD PMID:30768131 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions EXP [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] CTD PMID:20920558 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO cupric chloride results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atox1 antioxidant 1 copper chaperone multiple interactions ISO [cupric chloride results in increased abundance of Copper] which results in increased expression of ATOX1 mRNA; ATOX1 protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper] CTD PMID:32278528 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
JBrowse link
G Atp7a ATPase copper transporting alpha increases transport
increases expression
multiple interactions
decreases glutathionylation
affects localization
ISO
EXP
ATP7A protein results in increased transport of cupric chloride
cupric chloride results in increased expression of ATP7A protein
cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein]; cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]
cupric chloride results in decreased glutathionylation of ATP7A protein
cupric chloride affects the localization of ATP7A protein
Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
ATP7A protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7A protein results in decreased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]]; cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]
CTD PMID:11092760, PMID:16317117, PMID:17009961, PMID:20566629, PMID:21242307, PMID:23174565, PMID:25337692, PMID:32278528 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Atp7b ATPase copper transporting beta decreases response to substance
affects localization
multiple interactions
ISO
EXP
ATP7B protein results in decreased susceptibility to cupric chloride
cupric chloride affects the localization of ATP7B protein
ATP7B protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7B protein results in increased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
CTD PMID:10728692, PMID:16799059, PMID:21242307, PMID:24343273, PMID:32278528 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Bace1 beta-secretase 1 increases expression EXP cupric chloride results in increased expression of BACE1 mRNA; cupric chloride results in increased expression of BACE1 protein CTD PMID:22542740 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO cupric chloride results in increased expression of BAG3 mRNA CTD PMID:17211630 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO cupric chloride results in increased expression of BAX protein
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of BAX protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]
CTD PMID:21035945, PMID:22239859, PMID:23313662, PMID:24170445, PMID:29803612 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein]
[Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein
cupric chloride results in decreased expression of BCL2 protein
CTD PMID:20920558, PMID:21911303, PMID:23313662, PMID:24170445 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO cupric chloride results in decreased expression of BCL2L1 protein CTD PMID:23313662, PMID:24170445 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO cupric chloride results in increased expression of BID mRNA CTD PMID:17211630 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO cupric chloride results in increased expression of BLVRB mRNA CTD PMID:17211630 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G C1qtnf4 C1q and TNF related 4 increases expression ISO cupric chloride results in increased expression of C1QTNF4 mRNA CTD PMID:17211630 NCBI chr 3:79,713,580...79,718,018
Ensembl chr 3:79,713,567...79,718,025
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
decreases activity
EXP
ISO
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP3 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]
cupric chloride results in increased expression of CASP3 protein
cupric chloride results in increased activity of CASP3 protein
cupric chloride results in decreased activity of CASP3 protein
CTD PMID:11239917, PMID:18056745, PMID:20920558, PMID:21035945, PMID:22954531, PMID:23313662, PMID:24170445, PMID:29803612 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions EXP
ISO
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein]
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]
CTD PMID:20920558, PMID:21035945 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases expression ISO cupric chloride results in increased expression of CASP8 protein CTD PMID:23313662 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
EXP
ISO
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein]
cupric chloride results in increased expression of CASP9 protein
CTD PMID:20920558, PMID:23313662, PMID:24170445 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] CTD PMID:29803612 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO cupric chloride results in increased expression of CCN1 mRNA CTD PMID:17211630 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccs copper chaperone for superoxide dismutase multiple interactions ISO cupric chloride results in increased degradation of and results in decreased expression of CCS protein CTD PMID:16531609 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cd63 Cd63 molecule decreases expression ISO cupric chloride results in decreased expression of CD63 mRNA CTD PMID:17211630 NCBI chr 7:3,320,250...3,335,583
Ensembl chr 7:3,320,103...3,335,582
JBrowse link
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme affects expression ISO cupric chloride affects the expression of CDC34 mRNA CTD PMID:17211630 NCBI chr 7:12,899,957...12,905,339
Ensembl chr 7:12,899,958...12,905,339
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression ISO cupric chloride affects the expression of CDKN1A mRNA CTD PMID:17211630 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B affects expression ISO cupric chloride affects the expression of CDKN1B protein CTD PMID:23313662 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression ISO cupric chloride results in increased expression of CHORDC1 mRNA CTD PMID:17211630 NCBI chr 8:17,421,552...17,445,513
Ensembl chr 8:17,421,557...17,446,165
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression ISO cupric chloride results in decreased expression of CKMT2 protein CTD PMID:29617964 NCBI chr 2:21,422,680...21,452,797
Ensembl chr 2:21,422,818...21,437,193
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO cupric chloride results in increased expression of CKS2 mRNA CTD PMID:17211630 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Clcn6 chloride voltage-gated channel 6 increases expression ISO cupric chloride results in increased expression of CLCN6 mRNA CTD PMID:17211630 NCBI chr 5:164,811,815...164,844,554
Ensembl chr 5:164,811,816...164,844,586
JBrowse link
G Clcn7 chloride voltage-gated channel 7 affects expression ISO cupric chloride affects the expression of CLCN7 mRNA CTD PMID:17211630 NCBI chr10:14,492,844...14,518,167
Ensembl chr10:14,492,844...14,516,894
JBrowse link
G Cldnd1 claudin domain containing 1 increases expression ISO cupric chloride results in increased expression of CLDND1 mRNA CTD PMID:17211630 NCBI chr11:43,986,352...43,992,703
Ensembl chr11:43,986,386...43,992,598
JBrowse link
G Clu clusterin multiple interactions
increases expression
ISO cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
cupric chloride results in increased expression of CLU mRNA
CTD PMID:17211630, PMID:21242307 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Commd1 copper metabolism domain containing 1 decreases response to substance
multiple interactions
decreases expression
ISO
EXP
COMMD1 protein results in decreased susceptibility to cupric chloride
cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]
[COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein
cupric chloride results in decreased expression of COMMD1 mRNA; cupric chloride results in decreased expression of COMMD1 protein
CTD PMID:17211630, PMID:24691167, PMID:25007851 NCBI chr14:107,664,321...107,759,974
Ensembl chr14:107,664,255...107,760,191
JBrowse link
G Commd10 COMM domain containing 10 decreases expression ISO cupric chloride results in decreased expression of COMMD10 mRNA CTD PMID:17211630 NCBI chr18:41,022,487...41,158,374
Ensembl chr18:41,022,552...41,154,932
JBrowse link
G Commd2 COMM domain containing 2 decreases expression ISO cupric chloride results in decreased expression of COMMD2 mRNA CTD PMID:17211630 NCBI chr 2:147,774,767...147,779,013
Ensembl chr 2:147,774,767...147,779,013
JBrowse link
G Commd3 COMM domain containing 3 decreases expression ISO cupric chloride results in decreased expression of COMMD3 mRNA CTD PMID:17211630 NCBI chr17:85,356,042...85,359,835
Ensembl chr17:85,356,042...85,359,833
JBrowse link
G Commd4 COMM domain containing 4 decreases expression ISO cupric chloride results in decreased expression of COMMD4 mRNA CTD PMID:17211630 NCBI chr 8:61,833,340...61,836,872
Ensembl chr 8:61,833,326...61,836,945
JBrowse link
G Commd5 COMM domain containing 5 decreases expression ISO cupric chloride results in decreased expression of COMMD5 mRNA CTD PMID:17211630 NCBI chr 7:117,963,213...117,965,010
Ensembl chr 7:118,502,676...118,504,097
Ensembl chr 7:118,502,676...118,504,097
JBrowse link
G Commd6 COMM domain containing 6 decreases expression ISO cupric chloride results in decreased expression of COMMD6 mRNA CTD PMID:17211630 NCBI chr15:86,136,096...86,142,672
Ensembl chr15:86,136,096...86,142,672
JBrowse link
G Commd7 COMM domain containing 7 decreases expression ISO cupric chloride results in decreased expression of COMMD7 mRNA CTD PMID:17211630 NCBI chr 3:149,101,242...149,115,227
Ensembl chr 3:149,101,243...149,115,209
JBrowse link
G Commd8 COMM domain containing 8 decreases expression ISO cupric chloride results in decreased expression of COMMD8 mRNA CTD PMID:17211630 NCBI chr14:38,612,408...38,622,586
Ensembl chr14:38,612,408...38,622,580
JBrowse link
G Cox16 cytochrome c oxidase assembly factor COX16 affects expression ISO cupric chloride affects the expression of COX16 mRNA CTD PMID:17211630 NCBI chr 6:105,195,387...105,214,366
Ensembl chr 6:105,201,395...105,214,329
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression ISO cupric chloride results in decreased expression of COX5B protein CTD PMID:29617964 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 increases expression ISO cupric chloride results in increased expression of COX6A1 protein CTD PMID:29617964 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
JBrowse link
G Cp ceruloplasmin increases expression ISO cupric chloride results in increased expression of CP mRNA CTD PMID:15741220 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cplx2 complexin 2 decreases expression ISO cupric chloride results in decreased expression of CPLX2 protein CTD PMID:29617964 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835
JBrowse link
G Cryab crystallin, alpha B increases expression ISO cupric chloride results in increased expression of CRYAB mRNA CTD PMID:17211630 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cstb cystatin B affects binding ISO CSTB protein binds to cupric chloride CTD PMID:16939620 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
JBrowse link
G Ctsb cathepsin B multiple interactions
decreases expression
ISO PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB protein]
cupric chloride results in decreased expression of CTSB mRNA; cupric chloride results in decreased expression of CTSB protein
CTD PMID:32512069 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of CTSD mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSD mRNA]
CTD PMID:32512069 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP [cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein CTD PMID:20920558 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 decreases expression ISO cupric chloride results in decreased expression of CYFIP2 mRNA CTD PMID:17211630 NCBI chr10:31,278,746...31,419,235
Ensembl chr10:31,278,746...31,419,235
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases stability
multiple interactions
ISO cupric chloride results in increased stability of CYP1A1 mRNA; cupric chloride results in increased stability of CYP1A1 protein
[1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]
CTD PMID:19896525 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO cupric chloride results in increased expression of CYP27A1 mRNA CTD PMID:17211630 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of N'-nitrosonornicotine CTD PMID:32672941 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression ISO cupric chloride results in increased expression of CYP2C38 mRNA CTD PMID:17211630 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
EXP
ISO
pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA]
cupric chloride results in increased expression of DDIT3 mRNA
CTD PMID:17211630, PMID:20920558 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO cupric chloride results in increased expression of DKK1 mRNA CTD PMID:17211630 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dmd dystrophin increases expression ISO cupric chloride results in increased expression of DMD mRNA CTD PMID:17211630 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO cupric chloride results in increased expression of DNAJB1 mRNA CTD PMID:17211630 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO cupric chloride results in increased expression of DPYSL2 protein CTD PMID:29617964 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Dpysl5 dihydropyrimidinase-like 5 increases expression ISO cupric chloride results in increased expression of DPYSL5 protein CTD PMID:29617964 NCBI chr 6:26,939,696...27,024,129
Ensembl chr 6:26,939,697...27,024,129
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO cupric chloride results in increased expression of DUSP1 mRNA CTD PMID:17211630 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Egr1 early growth response 1 affects expression ISO cupric chloride affects the expression of EGR1 mRNA CTD PMID:17211630 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elac2 elaC ribonuclease Z 2 affects expression ISO cupric chloride affects the expression of ELAC2 mRNA CTD PMID:17211630 NCBI chr10:51,478,378...51,501,167
Ensembl chr10:51,478,378...51,501,165
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO cupric chloride results in increased expression of ELOVL1 mRNA CTD PMID:17211630 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483
JBrowse link
G Eml4 EMAP like 4 decreases expression ISO cupric chloride results in decreased expression of EML4 mRNA CTD PMID:17211630 NCBI chr 6:6,618,370...6,674,550
Ensembl chr 6:6,619,076...6,674,554
JBrowse link
G Enam enamelin affects expression ISO cupric chloride affects the expression of ENAM mRNA CTD PMID:17211630 NCBI chr14:21,194,635...21,219,529
Ensembl chr14:21,194,664...21,219,454
JBrowse link
G Endog endonuclease G increases expression ISO cupric chloride results in increased expression of ENDOG protein CTD PMID:22239859 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
affects response to substance
decreases expression
ISO cupric chloride inhibits the reaction [Estradiol binds to ESR1 protein]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 mRNA]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 mRNA]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 protein]
cupric chloride results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to cupric chloride
cupric chloride results in decreased expression of ESR1 mRNA; cupric chloride results in decreased expression of ESR1 protein
CTD PMID:12746304, PMID:17716812 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G F2 coagulation factor II increases expression ISO cupric chloride results in increased expression of F2 mRNA CTD PMID:17211630 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fam219a family with sequence similarity 219, member A increases expression ISO cupric chloride results in increased expression of FAM219A mRNA CTD PMID:17211630 NCBI chr 5:57,896,824...57,947,569
Ensembl chr 5:57,897,368...57,947,183
JBrowse link
G Fam89b family with sequence similarity 89, member B increases expression ISO cupric chloride results in increased expression of FAM89B mRNA CTD PMID:17211630 NCBI chr 1:221,085,894...221,087,449
Ensembl chr 1:221,085,895...221,087,449
JBrowse link
G Fetub fetuin B increases expression ISO cupric chloride results in increased expression of FETUB mRNA CTD PMID:17211630 NCBI chr11:81,648,890...81,660,472
Ensembl chr11:81,648,885...81,660,395
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO [amlexanox binds to FGF1 protein] inhibits the reaction [cupric chloride results in increased oxidation of FGF1 protein] CTD PMID:16300395 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 affects expression ISO cupric chloride affects the expression of FGFR1 mRNA CTD PMID:17211630 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fhl3 four and a half LIM domains 3 increases expression ISO cupric chloride results in increased expression of FHL3 mRNA CTD PMID:17211630 NCBI chr 5:142,688,962...142,696,330
Ensembl chr 5:142,689,026...142,696,383
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression ISO cupric chloride results in increased expression of FKBP4 mRNA CTD PMID:17211630 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases expression ISO cupric chloride results in decreased expression of FMO5 mRNA CTD PMID:17211630 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO cupric chloride results in increased expression of FOS mRNA CTD PMID:17211630 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression ISO cupric chloride results in increased expression of FUBP1 protein CTD PMID:29617964 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 affects expression ISO cupric chloride affects the expression of FXYD2 mRNA CTD PMID:17211630 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon increases expression ISO cupric chloride results in increased expression of GABRE mRNA CTD PMID:17211630 NCBI chr  X:152,220,180...152,237,347
Ensembl chr  X:152,218,707...152,237,361
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO cupric chloride results in increased expression of GADD45A mRNA CTD PMID:17211630 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO cupric chloride results in increased expression of GCLC mRNA CTD PMID:17211630 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO cupric chloride results in increased expression of GCLM mRNA CTD PMID:17211630, PMID:24343273 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 increases expression ISO cupric chloride results in increased expression of GDI1 protein CTD PMID:29617964 NCBI chr  X:156,400,734...156,407,396
Ensembl chr  X:156,400,736...156,407,404
JBrowse link
G Gla galactosidase, alpha increases expression ISO cupric chloride results in increased expression of GLA mRNA CTD PMID:17211630 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression ISO cupric chloride results in decreased expression of GLUD1 mRNA CTD PMID:17211630 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gtpbp2 GTP binding protein 2 affects expression ISO cupric chloride affects the expression of GTPBP2 mRNA CTD PMID:17211630 NCBI chr 9:17,198,957...17,208,456
Ensembl chr 9:17,198,957...17,209,220
JBrowse link
G Gtpbp6 GTP binding protein 6 (putative) increases expression ISO cupric chloride results in increased expression of GTPBP6 mRNA CTD PMID:17211630 NCBI chr12:52,637,000...52,640,869
Ensembl chr12:52,637,000...52,640,839
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression ISO cupric chloride results in increased expression of HAMP mRNA CTD PMID:17211630 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hexa hexosaminidase subunit alpha decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of HEXA mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of HEXA mRNA]
CTD PMID:32512069 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases stability
affects localization
decreases hydroxylation
ISO Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; cupric chloride results in decreased hydroxylation of and results in decreased degradation of HIF1A protein
cupric chloride affects the localization of HIF1A protein
CTD PMID:15741220, PMID:19074761 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hk1 hexokinase 1 decreases activity EXP cupric chloride results in decreased activity of HK1 protein CTD PMID:22349057 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO cupric chloride results in increased expression of HMOX1 mRNA; cupric chloride results in increased expression of HMOX1 protein CTD PMID:17211630, PMID:21242307, PMID:24343273 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO cupric chloride results in increased expression of HSP90AA1 mRNA CTD PMID:17211630 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA] CTD PMID:20920558 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression ISO cupric chloride affects the expression of HSPA1A mRNA CTD PMID:20945374 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO cupric chloride results in increased expression of HSPA1B mRNA CTD PMID:17211630 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA] CTD PMID:20920558 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO cupric chloride results in decreased expression of HSPA9 protein CTD PMID:29617964 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO cupric chloride results in increased expression of HSPB1 mRNA CTD PMID:17211630 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Id2 inhibitor of DNA binding 2 affects expression ISO cupric chloride affects the expression of ID2 mRNA CTD PMID:17211630 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO cupric chloride results in decreased expression of IDH3A protein CTD PMID:29617964 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Ier2 immediate early response 2 increases expression ISO cupric chloride results in increased expression of IER2 mRNA CTD PMID:17211630 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ier5 immediate early response 5 increases expression ISO cupric chloride results in increased expression of IER5 mRNA CTD PMID:17211630 NCBI chr13:72,742,210...72,744,302
Ensembl chr13:72,742,210...72,744,303
JBrowse link
G Ifng interferon gamma multiple interactions ISO cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO cupric chloride results in increased expression of IGF1 mRNA CTD PMID:17211630 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Ighmbp2 immunoglobulin mu DNA binding protein 2 increases expression ISO cupric chloride results in increased expression of IGHMBP2 mRNA CTD PMID:17211630 NCBI chr 1:218,509,274...218,531,922
Ensembl chr 1:218,508,950...218,532,142
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma increases expression ISO cupric chloride results in increased expression of IKBKG mRNA CTD PMID:17211630 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il1a interleukin 1 alpha increases secretion ISO cupric chloride results in increased secretion of IL1A protein CTD PMID:22954531 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il6 interleukin 6 multiple interactions ISO cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:23285694 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Immt inner membrane mitochondrial protein decreases expression ISO cupric chloride results in decreased expression of IMMT protein CTD PMID:29617964 NCBI chr 4:99,753,446...99,789,921
Ensembl chr 4:99,753,500...99,792,484
JBrowse link
G Irs2 insulin receptor substrate 2 increases expression ISO cupric chloride results in increased expression of IRS2 mRNA CTD PMID:17211630 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO cupric chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
[Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein
CTD PMID:17211630, PMID:21911303, PMID:30768131 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kdm2a lysine demethylase 2A increases expression ISO cupric chloride results in increased expression of KDM2A mRNA CTD PMID:17211630 NCBI chr 1:219,566,130...219,642,294
Ensembl chr 1:219,566,156...219,640,294
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO cupric chloride results in increased expression of KDM3A mRNA CTD PMID:17211630 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kif5a kinesin family member 5A decreases activity
multiple interactions
ISO cupric chloride results in decreased activity of KIF5A protein
Cysteine inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Dithiothreitol inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Egtazic Acid inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]
CTD PMID:24853401 NCBI chr 7:70,515,832...70,552,897
Ensembl chr 7:70,513,343...70,556,827
JBrowse link
G Klf6 Kruppel-like factor 6 affects expression ISO cupric chloride affects the expression of KLF6 mRNA CTD PMID:17211630 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Kng2 kininogen 2 increases expression ISO cupric chloride results in increased expression of KNG1 mRNA; cupric chloride results in increased expression of KNG2 mRNA CTD PMID:17211630 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of LAMP1 mRNA; cupric chloride results in decreased expression of LAMP1 protein
PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 protein]
CTD PMID:32512069 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of LAMP2 mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP2 mRNA]
CTD PMID:32512069 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO cupric chloride results in increased expression of LCAT mRNA CTD PMID:17211630 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lox lysyl oxidase increases activity
multiple interactions
ISO cupric chloride results in increased activity of LOX protein
Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]
CTD PMID:22367676, PMID:25044713 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Ly6e lymphocyte antigen 6 family member E increases expression ISO cupric chloride results in increased expression of LY6E mRNA CTD PMID:17211630 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Mad2l1bp MAD2L1 binding protein increases expression ISO cupric chloride results in increased expression of MAD2L1BP mRNA CTD PMID:17211630 NCBI chr 9:17,217,141...17,221,465
Ensembl chr 9:17,216,495...17,221,434
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO cupric chloride results in increased expression of MAFG mRNA CTD PMID:17211630 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO cupric chloride results in increased expression of MAP1LC3B mRNA
Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]; cupric chloride inhibits the reaction [3-methyladenine results in decreased expression of MAP1LC3B protein modified form]; PP242 promotes the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]
CTD PMID:17211630, PMID:32512069 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein CTD PMID:20920558 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein CTD PMID:20920558 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP
ISO
[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]
CTD PMID:11239917, PMID:20920558, PMID:30768131 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] CTD PMID:19789329 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] CTD PMID:19789329 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mdh2 malate dehydrogenase 2 increases expression ISO cupric chloride results in increased expression of MDH2 protein CTD PMID:29617964 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Med15 mediator complex subunit 15 increases expression ISO cupric chloride results in increased expression of MED15 mRNA CTD PMID:17211630 NCBI chr11:87,553,868...87,628,631
Ensembl chr11:87,553,868...87,628,502
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein CTD PMID:24193513 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor increases expression ISO cupric chloride results in increased expression of MLLT11 mRNA CTD PMID:17211630 NCBI chr 2:196,392,936...196,402,106
Ensembl chr 2:196,392,938...196,402,106
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases secretion EXP cupric chloride results in increased secretion of MMP2 protein CTD PMID:11045606 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mrpl4 mitochondrial ribosomal protein L4 increases expression ISO cupric chloride results in increased expression of MRPL4 mRNA CTD PMID:17211630 NCBI chr 8:22,021,213...22,027,228
Ensembl chr 8:22,021,213...22,027,228
JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO cupric chloride results in increased expression of MSRB1 mRNA CTD PMID:17211630 NCBI chr10:14,105,750...14,111,463
Ensembl chr10:14,105,750...14,111,463
JBrowse link
G Mt1 metallothionein 1 increases expression EXP
ISO
cupric chloride results in increased expression of MT1A mRNA CTD PMID:17211630, PMID:23174565 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression
affects expression
ISO
EXP
cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]
cupric chloride results in increased expression of MT2A mRNA
cupric chloride affects the expression of MT2A mRNA
CTD PMID:17211630, PMID:17409708, PMID:19789329, PMID:20945374, PMID:23174565 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO cupric chloride results in increased phosphorylation of MTOR protein CTD PMID:32512069 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO cupric chloride results in increased expression of NCF2 mRNA CTD PMID:17211630 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO cupric chloride results in decreased expression of NDUFS1 protein CTD PMID:29617964 NCBI chr 9:69,919,863...69,953,182
Ensembl chr 9:69,919,867...69,953,182
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO cupric chloride results in decreased expression of NDUFS4 protein CTD PMID:29617964 NCBI chr 2:46,372,488...46,476,162
Ensembl chr 2:46,372,518...46,476,203
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 decreases expression ISO cupric chloride results in decreased expression of NDUFV1 protein CTD PMID:29617964 NCBI chr 1:219,254,293...219,259,328
Ensembl chr 1:219,254,279...219,259,448
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 decreases expression ISO cupric chloride results in decreased expression of NDUFV3 protein CTD PMID:29617964 NCBI chr20:10,265,826...10,275,298
Ensembl chr20:10,265,806...10,275,304
JBrowse link
G Nefl neurofilament light decreases expression ISO cupric chloride results in decreased expression of NEFL protein CTD PMID:29617964 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nfix nuclear factor I X decreases expression ISO cupric chloride results in decreased expression of NFIX mRNA CTD PMID:17211630 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression EXP cupric chloride results in decreased expression of NFKBIA protein CTD PMID:24530511 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO cupric chloride results in increased expression of NME1 protein CTD PMID:29617964 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO
EXP
cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]
cupric chloride results in increased expression of NOS2 protein
CTD PMID:8975779, PMID:23313662, PMID:24170445, PMID:24530511 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nup107 nucleoporin 107 increases expression ISO cupric chloride results in increased expression of NUP107 mRNA CTD PMID:17211630 NCBI chr 7:60,781,724...60,825,225
Ensembl chr 7:60,781,729...60,825,242
JBrowse link
G P2rx2 purinergic receptor P2X 2 multiple interactions EXP cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr12:52,397,666...52,401,005
Ensembl chr12:52,397,792...52,401,015
JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 affects expression ISO cupric chloride affects the expression of P3H4 mRNA CTD PMID:17211630 NCBI chr10:88,318,231...88,325,326
Ensembl chr10:88,318,817...88,325,326
JBrowse link
G Palld palladin, cytoskeletal associated protein increases expression ISO cupric chloride results in increased expression of PALLD mRNA CTD PMID:17211630 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Paqr8 progestin and adipoQ receptor family member 8 decreases expression ISO cupric chloride results in decreased expression of PAQR8 mRNA CTD PMID:17211630 NCBI chr 9:27,005,270...27,054,591
Ensembl chr 9:27,034,022...27,051,002
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
ISO [Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein
cupric chloride results in increased expression of PARP1 protein
CTD PMID:19789329, PMID:21035945, PMID:23313662 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcm1 pericentriolar material 1 decreases expression ISO cupric chloride results in decreased expression of PCM1 mRNA CTD PMID:17211630 NCBI chr16:54,040,721...54,137,675
Ensembl chr16:54,040,721...54,137,660
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression ISO cupric chloride results in decreased expression of PDIA3 protein CTD PMID:29617964 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO cupric chloride results in decreased expression of PDZK1 mRNA CTD PMID:17211630 NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323
JBrowse link
G Peg10 paternally expressed 10 decreases expression ISO cupric chloride results in decreased expression of PEG10 mRNA CTD PMID:17211630 NCBI chr 4:29,795,524...29,804,517 JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression ISO cupric chloride results in increased expression of PGAM1 protein CTD PMID:29617964 NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
ISO cupric chloride promotes the reaction [Estradiol results in increased expression of PGR mRNA]; cupric chloride promotes the reaction [Estradiol results in increased expression of PGR protein]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR mRNA]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR protein]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR protein]
cupric chloride results in increased expression of PGR mRNA; cupric chloride results in increased expression of PGR protein
CTD PMID:12746304 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein decreases expression ISO cupric chloride results in decreased expression of PHYHIP mRNA CTD PMID:17211630 NCBI chr15:52,148,737...52,160,283
Ensembl chr15:52,767,442...52,778,687
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 decreases expression ISO cupric chloride results in decreased expression of PITPNC1 mRNA CTD PMID:17211630 NCBI chr10:95,429,879...95,697,734 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
ISO cupric chloride results in increased expression of PMAIP1 mRNA
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of PMAIP1 protein
CTD PMID:20713136, PMID:21035945 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pomp proteasome maturation protein increases expression ISO cupric chloride results in increased expression of POMP mRNA CTD PMID:17211630 NCBI chr12:8,746,948...8,759,433
Ensembl chr12:8,746,855...8,759,599
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO cupric chloride results in increased expression of PRDX1 mRNA CTD PMID:17211630 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO cupric chloride results in decreased expression of PRDX3 protein CTD PMID:29617964 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257
JBrowse link
G Prnp prion protein multiple interactions
increases expression
ISO
EXP
[NADP co-treated with cupric chloride] promotes the reaction [PRNP protein binds to PRNP protein]
bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein]
cupric chloride results in increased expression of PRNP mRNA; cupric chloride results in increased expression of PRNP protein
CTD PMID:16148034, PMID:16990274 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa multiple interactions ISO ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; aspartyl-alanyl-histidyl-lysine inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; cupric chloride binds to and results in decreased activity of PROC protein CTD PMID:11820775 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Psmb2 proteasome 20S subunit beta 2 increases expression ISO cupric chloride results in increased expression of PSMB2 mRNA CTD PMID:17211630 NCBI chr 5:144,702,004...144,734,220
Ensembl chr 5:144,701,949...144,734,257
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 increases expression ISO cupric chloride results in increased expression of PSMB3 mRNA CTD PMID:17211630 NCBI chr10:85,646,646...85,653,729
Ensembl chr10:85,646,633...85,653,729
JBrowse link
G Psmb7 proteasome 20S subunit beta 7 increases expression ISO cupric chloride results in increased expression of PSMB7 mRNA CTD PMID:17211630 NCBI chr 3:22,890,072...22,951,718
Ensembl chr 3:22,871,105...22,952,063
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 increases expression ISO cupric chloride results in increased expression of PSMC1 mRNA CTD PMID:17211630 NCBI chr 6:124,123,283...124,135,644
Ensembl chr 6:124,123,228...124,135,658
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 increases expression ISO cupric chloride results in increased expression of PSMC4 mRNA CTD PMID:17211630 NCBI chr 1:84,978,220...84,986,536
Ensembl chr 1:84,978,206...84,986,581
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 increases expression ISO cupric chloride results in increased expression of PSMD1 mRNA CTD PMID:17211630 NCBI chr 9:93,080,618...93,155,033
Ensembl chr 9:93,080,615...93,155,027
JBrowse link
G Psmd11 proteasome 26S subunit, non-ATPase 11 increases expression ISO cupric chloride results in increased expression of PSMD11 mRNA CTD PMID:17211630 NCBI chr10:67,810,655...67,857,562
Ensembl chr10:67,810,655...67,857,223
JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 increases expression ISO cupric chloride results in increased expression of PSMD13 mRNA CTD PMID:17211630 NCBI chr 1:213,636,159...213,648,499
Ensembl chr 1:213,636,093...213,648,488
JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 increases expression ISO cupric chloride results in increased expression of PSMD14 mRNA CTD PMID:17211630 NCBI chr 3:47,578,449...47,673,330
Ensembl chr 3:47,578,384...47,673,338
JBrowse link
G Psmd2 proteasome 26S subunit, non-ATPase 2 increases expression ISO cupric chloride results in increased expression of PSMD2 mRNA CTD PMID:17211630 NCBI chr11:83,934,098...83,944,725
Ensembl chr11:83,934,087...83,944,763
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO cupric chloride results in increased expression of PTGS2 protein CTD PMID:23313662, PMID:24170445 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O decreases expression ISO cupric chloride results in decreased expression of PTPRO mRNA CTD PMID:17211630 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677
JBrowse link
G Pura purine rich element binding protein A decreases expression ISO cupric chloride results in decreased expression of PURA protein CTD PMID:29617964 NCBI chr18:29,104,712...29,114,918
Ensembl chr18:29,110,242...29,111,156
JBrowse link
G Qk quaking increases expression ISO cupric chloride results in increased expression of QKI mRNA CTD PMID:17211630 NCBI chr 1:50,983,647...51,050,692 JBrowse link
G Ralgapa1 Ral GTPase activating protein catalytic subunit alpha 1 affects expression ISO cupric chloride affects the expression of RALGAPA1 mRNA CTD PMID:17211630 NCBI chr 6:76,386,971...76,661,530
Ensembl chr 6:76,396,784...76,608,864
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP cupric chloride results in increased phosphorylation of and affects the localization of RELA protein CTD PMID:24530511 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rhob ras homolog family member B decreases expression ISO cupric chloride results in decreased expression of ARHB mRNA CTD PMID:17211630 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rnf181 ring finger protein 181 affects expression ISO cupric chloride affects the expression of RNF181 mRNA CTD PMID:17211630 NCBI chr 4:100,222,087...100,228,809
Ensembl chr 4:100,222,106...100,228,809
JBrowse link
G Rpl32 ribosomal protein L32 affects expression ISO cupric chloride affects the expression of RPL32 mRNA CTD PMID:17211630 NCBI chr 4:147,715,480...147,719,044
Ensembl chr 6:145,777,318...145,777,767
Ensembl chr 4:145,777,318...145,777,767
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation ISO cupric chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:32512069 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO cupric chloride results in increased expression of RRAD mRNA CTD PMID:17211630 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 increases expression ISO cupric chloride results in increased expression of H2-D1 mRNA CTD PMID:17211630 NCBI chr20:5,374,990...5,378,536
Ensembl chr20:5,374,985...5,378,539
JBrowse link
G Rybp RING1 and YY1 binding protein affects expression ISO cupric chloride affects the expression of RYBP mRNA CTD PMID:17211630 NCBI chr 4:132,689,623...132,740,823
Ensembl chr 4:132,689,531...132,740,938
JBrowse link
G Sbds SBDS, ribosome maturation factor increases expression ISO cupric chloride results in increased expression of SBDS mRNA CTD PMID:17211630 NCBI chr12:29,921,443...29,930,602
Ensembl chr12:29,921,443...29,930,600
JBrowse link
G Sdf2 stromal cell derived factor 2 increases expression ISO cupric chloride results in increased expression of SDF2 mRNA CTD PMID:17211630 NCBI chr10:65,507,364...65,517,839
Ensembl chr10:65,507,364...65,517,838
JBrowse link
G Selenok selenoprotein K increases expression ISO cupric chloride results in increased expression of SELENOK mRNA CTD PMID:17211630 NCBI chr16:6,035,926...6,044,240
Ensembl chr16:6,035,926...6,044,239
JBrowse link
G Selenop selenoprotein P decreases expression ISO cupric chloride results in decreased expression of SELENOP mRNA CTD PMID:17211630 NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
JBrowse link
G Septin4 septin 4 decreases expression ISO cupric chloride results in decreased expression of SEPTIN4 protein CTD PMID:29617964 NCBI chr10:74,860,068...74,884,196
Ensembl chr10:74,861,714...74,884,196
JBrowse link
G Septin8 septin 8 decreases expression ISO cupric chloride results in decreased expression of SEPTIN8 protein CTD PMID:29617964 NCBI chr10:38,877,422...38,906,480
Ensembl chr10:38,877,422...38,906,482
JBrowse link
G Serpinf1 serpin family F member 1 increases expression ISO cupric chloride results in increased expression of SERPINF1 mRNA CTD PMID:17211630 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 multiple interactions EXP [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein CTD PMID:25007851 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions EXP [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Sirt7 sirtuin 7 increases expression ISO cupric chloride results in increased expression of SIRT7 mRNA CTD PMID:17211630 NCBI chr10:109,796,046...109,802,821
Ensembl chr10:109,796,020...109,802,739
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO cupric chloride inhibits the reaction [SLC11A2 protein results in increased uptake of Iron] CTD PMID:12220667 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc13a3 solute carrier family 13 member 3 decreases expression ISO cupric chloride results in decreased expression of SLC13A3 mRNA CTD PMID:17211630 NCBI chr 3:162,084,336...162,147,398
Ensembl chr 3:162,084,315...162,147,393
JBrowse link
G Slc22a18 solute carrier family 22, member 18 increases expression ISO cupric chloride results in increased expression of SLC22A18 mRNA CTD PMID:17211630 NCBI chr 1:216,676,330...216,700,632
Ensembl chr 1:216,677,373...216,700,641
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO cupric chloride results in increased expression of SLC2A1 mRNA CTD PMID:15741220 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO cupric chloride results in increased expression of SLC30A1 mRNA CTD PMID:24343273 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc31a1 solute carrier family 31 member 1 decreases expression
multiple interactions
EXP
ISO
cupric chloride results in decreased expression of SLC31A1 protein
SLC31A1 protein results in increased susceptibility to [cupric chloride results in increased abundance of Copper]
CTD PMID:24316150, PMID:24800945, PMID:32278528 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Snca synuclein alpha affects folding ISO cupric chloride affects the folding of SNCA protein CTD PMID:11553618 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression
increases response to substance
ISO cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form results in increased susceptibility to cupric chloride]; SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]
cupric chloride results in decreased expression of SOD1 protein
CTD PMID:15812313, PMID:24691167, PMID:29617964 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO cupric chloride results in decreased expression of SORBS1 mRNA CTD PMID:17211630 NCBI chr 1:259,373,921...259,502,108
Ensembl chr 1:259,376,933...259,484,569
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO cupric chloride results in increased expression of SPSB1 mRNA CTD PMID:17211630 NCBI chr 5:166,913,734...166,978,534
Ensembl chr 5:166,913,735...166,926,636
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO cupric chloride results in increased expression of SQSTM1 mRNA
Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]; PP242 inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]
CTD PMID:17211630, PMID:23313662, PMID:32512069 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 decreases expression ISO cupric chloride results in decreased expression of ST6GAL1 mRNA CTD PMID:17211630 NCBI chr11:80,927,601...80,981,424
Ensembl chr11:80,927,601...80,981,422
JBrowse link
G Stau1 staufen double-stranded RNA binding protein 1 decreases expression ISO cupric chloride results in decreased expression of STAU mRNA CTD PMID:17211630 NCBI chr 3:163,703,204...163,748,996
Ensembl chr 3:163,703,204...163,748,996
JBrowse link
G Stmn1 stathmin 1 decreases expression ISO cupric chloride results in decreased expression of STMN1 protein CTD PMID:29617964 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Syn2 synapsin II decreases expression ISO cupric chloride results in decreased expression of SYN2 protein CTD PMID:29617964 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096
JBrowse link
G Taf7l TATA-box binding protein associated factor 7-like increases expression ISO cupric chloride results in increased expression of TAF7L mRNA CTD PMID:17211630 NCBI chr  X:105,292,338...105,308,554
Ensembl chr  X:105,292,338...105,308,554
JBrowse link
G Taldo1 transaldolase 1 increases expression ISO cupric chloride results in increased expression of TALDO1 mRNA CTD PMID:17211630 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO cupric chloride inhibits the reaction [Paraquat affects the localization of TARDBP protein] CTD PMID:22879928 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tfdp2 transcription factor Dp-2 affects expression ISO cupric chloride affects the expression of TFDP2 mRNA CTD PMID:17211630 NCBI chr 8:104,040,795...104,181,228
Ensembl chr 8:104,040,934...104,176,446
JBrowse link
G Tfeb transcription factor EB decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of TFEB mRNA; cupric chloride results in decreased expression of TFEB protein
PP242 inhibits the reaction [cupric chloride results in decreased expression of TFEB protein]
CTD PMID:32512069 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
G Tkt transketolase increases expression ISO cupric chloride results in increased expression of TKT mRNA CTD PMID:17211630 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 decreases expression ISO cupric chloride results in decreased expression of TMED2 mRNA CTD PMID:17211630 NCBI chr12:37,471,259...37,480,344
Ensembl chr12:37,471,260...37,480,297
JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
increases expression
ISO
EXP
cupric chloride results in increased secretion of TNF protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; SC 514 inhibits the reaction [cupric chloride results in increased secretion of TNF protein]
cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
cupric chloride results in increased expression of TNF protein
CTD PMID:22954531, PMID:23285694, PMID:23313662, PMID:24170445, PMID:24530511 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 affects expression
multiple interactions
decreases expression
increases expression
ISO cupric chloride affects the expression of TRP53 mRNA
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]
cupric chloride results in decreased expression of TRP53 protein
cupric chloride results in increased expression of TRP53 protein
CTD PMID:23313662, PMID:24170445, PMID:29803612 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp73 tumor protein p73 affects expression
increases expression
ISO cupric chloride affects the expression of TRP73 protein
cupric chloride results in increased expression of TRP73 protein
CTD PMID:23313662, PMID:24170445 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Tpm1 tropomyosin 1 increases expression ISO cupric chloride results in increased expression of TPM1 protein CTD PMID:29617964 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Tppp tubulin polymerization promoting protein increases expression ISO cupric chloride results in increased expression of TPPP protein CTD PMID:29617964 NCBI chr 1:31,866,755...31,890,778
Ensembl chr 1:31,870,899...31,890,778
JBrowse link
G Traf5 TNF receptor-associated factor 5 increases expression ISO cupric chloride results in increased expression of TRAF5 mRNA CTD PMID:17211630 NCBI chr13:110,758,556...110,801,871
Ensembl chr13:110,758,761...110,784,209
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO cupric chloride results in increased expression of TRIB3 mRNA CTD PMID:17211630 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [cupric chloride results in increased abundance of Copper] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO cupric chloride results in increased expression of TXN mRNA CTD PMID:17211630 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnl1 thioredoxin-like 1 increases expression ISO cupric chloride results in increased expression of TXNL1 mRNA CTD PMID:17211630 NCBI chr18:59,056,454...59,086,278
Ensembl chr18:59,059,375...59,086,256
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO cupric chloride results in increased expression of TXNRD1 mRNA CTD PMID:17211630 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tyr tyrosinase multiple interactions ISO cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]] CTD PMID:11092760 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO cupric chloride promotes the reaction [Dimethyldithiocarbamate results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; cupric chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:1,723,135...1,745,147
Ensembl chr  X:1,723,174...1,741,701
JBrowse link
G Ubc ubiquitin C increases expression ISO cupric chloride results in increased expression of UBC mRNA CTD PMID:17211630 NCBI chr12:36,638,457...36,642,734
Ensembl chr12:36,638,457...36,642,734
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 increases expression ISO cupric chloride results in increased expression of UBR5 mRNA CTD PMID:17211630 NCBI chr 7:76,789,110...76,835,517
NCBI chr 7:76,839,661...76,907,441
Ensembl chr 7:76,789,531...76,853,840
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 increases expression ISO cupric chloride results in increased expression of UCHL1 protein CTD PMID:29617964 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 increases expression ISO cupric chloride results in increased expression of UFD1 mRNA CTD PMID:17211630 NCBI chr11:86,304,836...86,328,478
Ensembl chr11:86,304,815...86,328,469
JBrowse link
G Unkl unk like zinc finger increases expression ISO cupric chloride results in increased expression of UNKL mRNA CTD PMID:17211630 NCBI chr10:14,547,126...14,593,090
Ensembl chr10:14,547,172...14,590,762
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression ISO cupric chloride results in increased expression of UQCRC1 protein CTD PMID:29617964 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein decreases expression ISO cupric chloride results in decreased expression of UQCRH protein CTD PMID:29617964 NCBI chr 5:134,919,040...134,927,235
Ensembl chr 5:134,919,044...134,927,235
JBrowse link
G Utp11 UTP11, small subunit processome component increases expression ISO cupric chloride results in increased expression of UTP11 mRNA CTD PMID:17211630 NCBI chr 5:142,666,288...142,681,173
Ensembl chr 5:142,666,289...142,681,173
JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression ISO cupric chloride results in increased expression of VDAC1 protein CTD PMID:29617964 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdac2 voltage-dependent anion channel 2 increases expression ISO cupric chloride results in increased expression of VDAC2 protein CTD PMID:29617964 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO cupric chloride results in increased expression of VEGFA mRNA CTD PMID:15741220 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vps13b vacuolar protein sorting 13 homolog B affects expression ISO cupric chloride affects the expression of VPS13B mRNA CTD PMID:17211630 NCBI chr 7:74,118,834...74,722,341 JBrowse link
G Wdr74 WD repeat domain 74 affects expression ISO cupric chloride affects the expression of WDR74 mRNA CTD PMID:17211630 NCBI chr 1:224,933,906...224,938,659
Ensembl chr 1:224,933,529...224,938,662
JBrowse link
G Zfp12 zinc finger protein 12 increases expression ISO cupric chloride results in increased expression of ZNF12 mRNA CTD PMID:17211630 NCBI chr12:13,370,504...13,384,034 JBrowse link
G Znrd2 zinc ribbon domain containing 2 increases expression ISO cupric chloride results in increased expression of ZNRD2 mRNA CTD PMID:17211630 NCBI chr 1:221,087,803...221,089,586
Ensembl chr 1:221,087,803...221,089,586
JBrowse link
G Zswim6 zinc finger, SWIM-type containing 6 affects expression ISO cupric chloride affects the expression of ZSWIM6 mRNA CTD PMID:17211630 NCBI chr 2:38,978,042...39,042,886
Ensembl chr 2:38,979,865...39,007,976
JBrowse link
trifluoperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity ISO Trifluoperazine results in increased activity of ABCB1 protein CTD PMID:2900677 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ache acetylcholinesterase multiple interactions
increases activity
decreases expression
EXP
ISO
energostim inhibits the reaction [Trifluoperazine results in decreased expression of ACHE protein]
Trifluoperazine results in increased activity of ACHE protein
CTD PMID:15232633, PMID:29614332 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:19233221, PMID:21544200 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA CTD PMID:28366621 NCBI chr 5:14,262,352...14,367,898
Ensembl chr 5:14,262,349...14,367,898
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Trifluoperazine results in increased expression of BAX protein CTD PMID:21475906 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Trifluoperazine results in decreased expression of BCL2 protein CTD PMID:21475906 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of CAMK2A protein] CTD PMID:19233221 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein] CTD PMID:21544200 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO Trifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein] CTD PMID:9929743 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:21544200 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases oxidation ISO FMO2 protein results in increased oxidation of Trifluoperazine CTD PMID:26062974 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions ISO Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:15627515 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:15627515 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Trifluoperazine results in decreased expression of HIF1A protein CTD PMID:18822394 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IL12B protein] CTD PMID:16249388 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Trifluoperazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:21158687 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases activity EXP Trifluoperazine results in decreased activity of KCNN2 protein CTD PMID:10915830 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA CTD PMID:28366621 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK1 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Trifluoperazine inhibits the reaction [Dinoprost results in increased activity of MAPK1 protein] CTD PMID:11914123, PMID:21544200 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein] CTD PMID:21544200 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK3 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Trifluoperazine inhibits the reaction [Dinoprost results in increased activity of MAPK3 protein] CTD PMID:11914123, PMID:21544200 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO
EXP
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:21544200 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Trifluoperazine results in increased expression of MT1A mRNA CTD PMID:8128501 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MTOR protein] CTD PMID:21544200 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myl9 myosin light chain 9 multiple interactions EXP Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MYL9 protein]; Trifluoperazine inhibits the reaction [Ionomycin results in increased phosphorylation of MYL9 protein] CTD PMID:19233221 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases activity ISO Trifluoperazine results in decreased activity of NR3C1 protein CTD PMID:7887964 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] CTD PMID:21544200 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase affects localization
multiple interactions
ISO Trifluoperazine affects the localization of PRKN protein
PRKN protein affects the reaction [Trifluoperazine affects the localization of PRKN protein]
CTD PMID:28366621 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Prl prolactin increases expression ISO Trifluoperazine results in increased expression of PRL protein CTD PMID:2136057 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased localization of REL protein] CTD PMID:16249388 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP
ISO
Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Slc5a6 solute carrier family 5 member 6 multiple interactions ISO Trifluoperazine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116
JBrowse link
G Tfeb transcription factor EB multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases activity ISO Trifluoperazine results in decreased activity of TNFSF11 CTD PMID:21869564 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation
multiple interactions
increases activity
ISO UGT1A4 protein results in increased glucuronidation of Trifluoperazine
Finasteride inhibits the reaction [UGT1A4 protein results in increased glucuronidation of Trifluoperazine]; hecogenin inhibits the reaction [UGT1A4 protein results in increased glucuronidation of Trifluoperazine]; licochalcone A inhibits the reaction [Trifluoperazine results in increased activity of UGT1A4 protein]; Trifluoperazine inhibits the reaction [UGT1A4 protein results in increased glucuronidation of afloqualone]
CTD PMID:15135306, PMID:15475412, PMID:25393417, PMID:25448279, PMID:26875642 NCBI chr 9:95,256,628...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
zinc dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB1 mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]
CTD PMID:19714248 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB6 mRNA] CTD PMID:22202117 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein] CTD PMID:19429256 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Aco2 aconitase 2 multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in decreased activity of ACO2 protein CTD PMID:16624386 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Actb actin, beta multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of ACTB mRNA CTD PMID:31588059 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Adam2 ADAM metallopeptidase domain 2 decreases expression ISO zinc chloride results in decreased expression of ADAM2 mRNA CTD PMID:16870260 NCBI chr15:42,708,536...42,751,281
Ensembl chr15:42,708,387...42,751,330
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions
increases expression
ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein] CTD PMID:18509044 NCBI chr 9:9,431,888...9,585,883
Ensembl chr 9:9,431,860...9,585,865
JBrowse link
G Adm adrenomedullin multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ADM mRNA] CTD PMID:22202117 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions EXP zinc chloride inhibits the reaction [N(6)-cyclohexyladenosine binds to ADORA1 protein] CTD PMID:10413299 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Afp alpha-fetoprotein decreases expression ISO zinc chloride results in decreased expression of AFP mRNA CTD PMID:18947441 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ago2 argonaute RISC catalytic component 2 multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of AGO2 mRNA; [Clioquinol co-treated with zinc chloride] results in decreased expression of AGO2 protein CTD PMID:22415087 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of AK4 mRNA] CTD PMID:22202117 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO zinc chloride results in increased phosphorylation of AKT1 protein
wortmannin inhibits the reaction [zinc chloride results in increased phosphorylation of AKT1 protein]
CTD PMID:11340092 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO
EXP
[zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]] which affects the abundance of Mercury; zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]
lead nitrate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]; triethyllead acetate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]; zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]
zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of ALAD protein]
CTD PMID:2061546, PMID:14615064, PMID:22413763, PMID:24619859, PMID:24679358 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ALDOA mRNA] CTD PMID:22202117 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ALDOC mRNA] CTD PMID:22202117 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
increases activity
ISO
EXP
[zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of ALPL mRNA
zinc chloride results in increased activity of ALPL protein
Cadmium inhibits the reaction [zinc chloride results in increased activity of ALPL protein]; zinc chloride inhibits the reaction [Cadmium results in decreased activity of ALPL protein]
CTD PMID:19913120, PMID:26214600 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Ang angiogenin multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANG mRNA] CTD PMID:22202117 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANGPTL4 mRNA] CTD PMID:22202117 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankrd37 ankyrin repeat domain 37 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKRD37 mRNA] CTD PMID:22202117 NCBI chr16:49,463,016...49,465,905
Ensembl chr16:49,462,889...49,465,888
JBrowse link
G Ankzf1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKZF1 mRNA] CTD PMID:22202117 NCBI chr 9:82,393,619...82,400,537
Ensembl chr 9:82,393,672...82,400,530
JBrowse link
G Ar androgen receptor multiple interactions EXP Androgens inhibits the reaction [zinc chloride inhibits the reaction [Androgens binds to AR protein]]; Dithiothreitol inhibits the reaction [zinc chloride inhibits the reaction [Androgens binds to AR protein]]; zinc chloride inhibits the reaction [Androgens binds to AR protein] CTD PMID:6323860 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arg2 arginase 2 increases expression ISO zinc chloride results in increased expression of ARG2 mRNA CTD PMID:18947441 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arrb2 arrestin, beta 2 affects localization ISO zinc chloride affects the localization of ARRB2 protein CTD PMID:16959833 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein] CTD PMID:30768131 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO zinc chloride results in decreased expression of ATF4 mRNA CTD PMID:18947441 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO zinc chloride results in decreased expression of ATP6V1B2 mRNA CTD PMID:18947441 NCBI chr16:22,326,537...22,350,143
Ensembl chr16:22,326,529...22,350,155
JBrowse link
G Atp7b ATPase copper transporting beta decreases expression
increases expression
ISO zinc chloride results in decreased expression of ATP7B mRNA
zinc chloride results in increased expression of ATP7B mRNA
CTD PMID:18947441 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Bag3 BAG cochaperone 3 increases expression
multiple interactions
ISO zinc chloride results in increased expression of BAG3 mRNA
zinc chloride results in increased expression of and affects the localization of BAG3 protein
CTD PMID:12706811, PMID:16870260 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
[Citric Acid co-treated with zinc chloride] results in increased expression of BAX protein
zinc chloride affects the reaction [Cadmium Chloride results in increased expression of BAX protein]
zinc chloride promotes the reaction [Doxorubicin results in increased expression of BAX mRNA]
CTD PMID:16624386, PMID:19714248, PMID:28390674 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO zinc chloride promotes the reaction [Doxorubicin results in increased expression of BBC3 mRNA] CTD PMID:19714248 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in decreased expression of BCL2 protein; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BCL2 mRNA]; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BCL2 protein]; zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BCL2 mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of BCL2 mRNA]
CTD PMID:16624386, PMID:17786326, PMID:19714248 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO zinc chloride results in increased expression of BCL2A1 mRNA CTD PMID:21540303 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in decreased expression of BCL2L1 protein CTD PMID:16624386 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP zinc chloride affects the reaction [Cadmium Chloride affects the expression of BDNF mRNA] CTD PMID:29548726 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of BGLAP mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of BGLAP mRNA CTD PMID:19913120 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BHLHE40 mRNA] CTD PMID:22202117 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bnip3l BCL2 interacting protein 3 like multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BNIP3L mRNA] CTD PMID:22202117 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BOP1 mRNA] CTD PMID:22202117 NCBI chr 7:117,514,529...117,538,342
Ensembl chr 7:117,514,533...117,538,342
JBrowse link
G C3 complement C3 increases expression ISO zinc chloride results in increased expression of C3 mRNA CTD PMID:19428942 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Ca13 carbonic anhydrase 13 increases expression ISO zinc chloride results in increased expression of CAR13 mRNA CTD PMID:19000923 NCBI chr 2:88,282,961...88,314,254
Ensembl chr 2:88,282,961...88,314,254
JBrowse link
G Ca9 carbonic anhydrase 9 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CA9 mRNA] CTD PMID:22202117 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Cald1 caldesmon 1 increases expression ISO zinc chloride results in increased expression of CALD1 mRNA CTD PMID:16870260 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Casp12 caspase 12 multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in increased activity of CASP12 protein CTD PMID:16624386 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in increased activity of CASP3 protein CTD PMID:16624386 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 mRNA] CTD PMID:28390674 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
increases expression
increases activity
EXP
ISO
zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein]
zinc chloride results in increased expression of CAT mRNA
zinc chloride results in increased activity of CAT protein
CTD PMID:9330853, PMID:19429256, PMID:23726800 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO zinc chloride results in increased expression of CCL11 mRNA CTD PMID:19428942 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases expression ISO zinc chloride results in decreased expression of CCL17 mRNA CTD PMID:19428942 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 decreases expression ISO zinc chloride results in decreased expression of CCL19 mRNA CTD PMID:19428942 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO zinc chloride results in increased expression of CCL20 mRNA CTD PMID:19428942, PMID:21540303, PMID:27427241 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 decreases expression ISO zinc chloride results in decreased expression of CCL24 mRNA CTD PMID:19428942 NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 increases expression ISO zinc chloride results in increased expression of CCL26 mRNA CTD PMID:19428942 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO zinc chloride results in increased expression of CCNB1 mRNA CTD PMID:19000923 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride results in increased expression of CCNG1 mRNA] CTD PMID:16842966 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CCNG2 mRNA] CTD PMID:22202117 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 decreases expression ISO zinc chloride results in decreased expression of CCR6 mRNA CTD PMID:19428942 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Ccr8 C-C motif chemokine receptor 8 decreases expression ISO zinc chloride results in decreased expression of CCR8 mRNA CTD PMID:19428942 NCBI chr 8:128,779,552...128,782,531
Ensembl chr 8:128,781,395...128,782,456
JBrowse link
G Cd86 CD86 molecule decreases expression ISO zinc chloride results in decreased expression of CD86 protein CTD PMID:24284788 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cd9 CD9 molecule increases expression ISO zinc chloride results in increased expression of CD9 mRNA CTD PMID:16870260 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Cdh17 cadherin 17 decreases expression ISO zinc chloride results in decreased expression of CDH17 mRNA CTD PMID:18947441 NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in increased expression of CDKN1A protein CTD PMID:16624386 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO zinc chloride results in decreased expression of CDKN1B mRNA CTD PMID:21540303 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B decreases expression ISO zinc chloride results in decreased expression of CDKN2B mRNA CTD PMID:21540303 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cdr1 cerebellar degeneration related protein 1 decreases expression ISO zinc chloride results in decreased expression of CDR1 mRNA CTD PMID:16870260 NCBI chr  X:144,326,497...144,330,364 JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 increases expression ISO zinc chloride results in increased expression of CEACAM6 mRNA CTD PMID:18947441 NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317
JBrowse link
G Cftr CF transmembrane conductance regulator increases expression ISO zinc chloride results in increased expression of CFTR mRNA CTD PMID:16870260 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO zinc chloride results in increased expression of CHEK1 mRNA CTD PMID:19000923 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CITED2 mRNA] CTD PMID:22202117 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of COL1A1 mRNA CTD PMID:19913120 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Commd1 copper metabolism domain containing 1 multiple interactions EXP [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 NCBI chr14:107,664,321...107,759,974
Ensembl chr14:107,664,255...107,760,191
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO zinc chloride results in decreased expression of COX17 mRNA CTD PMID:18947441 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cp ceruloplasmin increases expression ISO zinc chloride results in increased expression of CP mRNA CTD PMID:18947441 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 increases expression ISO zinc chloride results in increased expression of CPS1 mRNA CTD PMID:16870260 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Crp C-reactive protein increases expression ISO zinc chloride results in increased expression of CRP mRNA CTD PMID:19428942 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf2 colony stimulating factor 2 increases expression
multiple interactions
ISO zinc chloride results in increased expression of CSF2 mRNA
zinc chloride results in increased expression of CSF2 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]
CTD PMID:18509044, PMID:21540303, PMID:27427241 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CSRP2 mRNA] CTD PMID:22202117 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO zinc chloride results in increased expression of CXCL1 mRNA CTD PMID:19428942 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO zinc chloride results in increased expression of CXCL11 mRNA CTD PMID:19428942 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 decreases expression ISO zinc chloride results in decreased expression of CXCL13 mRNA CTD PMID:19428942 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO zinc chloride results in increased expression of CXCL14 mRNA CTD PMID:19428942 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO zinc chloride results in increased expression of CXCL1 mRNA CTD PMID:19428942 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 decreases expression ISO zinc chloride results in decreased expression of CXCL6 mRNA CTD PMID:19428942 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases stability
multiple interactions
ISO zinc chloride results in increased stability of CYP1A1 mRNA; zinc chloride results in increased stability of CYP1A1 protein
zinc chloride inhibits the reaction [1,10-phenanthroline inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]
CTD PMID:19896525 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dcp1b decapping mRNA 1B multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of DCP1B mRNA CTD PMID:22415087 NCBI chr 4:151,249,654...151,287,018
Ensembl chr 4:151,250,041...151,285,702
JBrowse link
G Ddx21 DExD-box helicase 21 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of DDX21 mRNA] CTD PMID:22202117 NCBI chr20:32,213,147...32,232,632
Ensembl chr20:32,213,148...32,232,632
JBrowse link
G Dennd2b DENN domain containing 2B increases expression ISO zinc chloride results in increased expression of DENND2B mRNA CTD PMID:16870260 NCBI chr 1:174,137,120...174,290,533
Ensembl chr 1:174,137,120...174,289,647
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO zinc chloride results in increased expression of DHRS2 mRNA CTD PMID:16870260 NCBI chr15:33,876,701...33,891,559
Ensembl chr15:33,885,106...33,891,539
JBrowse link
G Dicer1 dicer 1 ribonuclease III multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of DICER1 protein CTD PMID:22415087 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Dll4 delta like canonical Notch ligand 4 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of DLL4 mRNA CTD PMID:31588059 NCBI chr 3:111,135,011...111,146,746
Ensembl chr 3:111,135,021...111,145,986
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP zinc chloride inhibits the reaction [ecopipam binds to DRD1 protein]; zinc chloride inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9109525 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP zinc chloride inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein] CTD PMID:9109525 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drosha drosha ribonuclease III multiple interactions ISO [Clioquinol co-treated with zinc chloride] affects the expression of DROSHA protein CTD PMID:22415087 NCBI chr 2:62,887,267...63,000,307
Ensembl chr 2:62,887,267...62,999,572
JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO DUOX1 protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein] CTD PMID:27427241 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation ISO zinc chloride results in increased phosphorylation of EGFR protein CTD PMID:21540303 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EGLN1 mRNA]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein] CTD PMID:16579968, PMID:22202117 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E mRNA; [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E protein CTD PMID:22415087 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions
increases activity
EXP zinc chloride results in increased phosphorylation of and results in increased activity of ELK1 protein
zinc chloride results in increased activity of ELK1 protein
CTD PMID:16960431, PMID:20412391 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Eno2 enolase 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ENO2 mRNA] CTD PMID:22202117 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Epo erythropoietin multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EPO protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA] CTD PMID:11090055 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 decreases expression ISO zinc chloride results in decreased expression of F2RL2 mRNA CTD PMID:16870260 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO zinc chloride results in decreased expression of FABP1 mRNA CTD PMID:18947441 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fam162a family with sequence similarity 162, member A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of FAM162A mRNA] CTD PMID:22202117 NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253
JBrowse link
G Fasn fatty acid synthase decreases expression ISO zinc chloride results in decreased expression of FASN mRNA CTD PMID:21540303 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of FOS mRNA] CTD PMID:22202117 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO zinc chloride results in increased expression of FOSL1 mRNA CTD PMID:19000923 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO zinc chloride results in decreased expression of FOXA2 mRNA CTD PMID:21540303 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxd1 forkhead box D1 increases expression ISO zinc chloride results in increased expression of FOXD1 mRNA CTD PMID:16870260 NCBI chr 2:28,460,068...28,462,488
Ensembl chr 2:28,460,068...28,462,488
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of G6PC protein] CTD PMID:22413763 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein] CTD PMID:18972399 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of GBE1 mRNA] CTD PMID:22202117 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLC mRNA] CTD PMID:18385089 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA] CTD PMID:18385089 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO zinc chloride results in increased expression of GPX2 mRNA CTD PMID:18947441 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 increases expression ISO zinc chloride results in increased expression of GRIK2 mRNA CTD PMID:16870260 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions EXP AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of GRIN2A protein]; zinc chloride results in increased expression of and results in increased phosphorylation of GRIN2A protein CTD PMID:12211081 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of GRIN2B protein]; zinc chloride results in increased expression of and results in increased phosphorylation of GRIN2B protein CTD PMID:12211081 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grm5 glutamate metabotropic receptor 5 multiple interactions
increases expression
EXP Copper inhibits the reaction [zinc chloride results in increased expression of GRM5 protein] CTD PMID:25007851 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO
EXP
[Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to zinc chloride
zinc chloride inhibits the reaction [Cadmium Chloride results in increased activity of GSR protein]; zinc chloride inhibits the reaction [Copper results in decreased activity of GSR protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]
CTD PMID:12632252, PMID:19429256, PMID:20600438, PMID:23726800 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP [Cadmium Chloride co-treated with zinc chloride] results in increased expression of GSTP1 protein CTD PMID:15602745 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gys1 glycogen synthase 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of GYS1 mRNA] CTD PMID:22202117 NCBI chr 1:101,427,195...101,447,092
Ensembl chr 1:101,427,195...101,447,092
JBrowse link
G H2ax H2A.X variant histone increases expression ISO zinc chloride results in increased expression of H2AX mRNA CTD PMID:18947441 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hcfc1r1 host cell factor C1 regulator 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HCFC1R1 mRNA] CTD PMID:22202117 NCBI chr10:12,994,229...12,995,674
Ensembl chr10:12,994,683...12,995,457
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of HDAC1 mRNA CTD PMID:31588059 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hells helicase, lymphoid specific increases expression ISO zinc chloride results in increased expression of HELLS mRNA CTD PMID:19000923 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Heph hephaestin decreases expression ISO zinc chloride results in decreased expression of HEPH mRNA CTD PMID:18947441 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP zinc chloride inhibits the reaction [2-phenylphenol results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [bitertanol results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Butylated Hydroxyanisole results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Butylated Hydroxytoluene results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [butylparaben results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [EPN oxon results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Permethrin results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [prothiophos results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [pyridaben results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [salinomycin results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [terbufos results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
affects splicing
ISO Cycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form]; zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]; zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
[Doxorubicin co-treated with zinc chloride] results in decreased expression of HIF1A mRNA
zinc chloride results in increased expression of HIF1A mRNA; zinc chloride results in increased expression of HIF1A mRNA alternative form; zinc chloride results in increased expression of HIF1A protein alternative form
zinc chloride affects the splicing of HIF1A mRNA
CTD PMID:11090055, PMID:11739637, PMID:16579968, PMID:19714248 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HILPDA mRNA] CTD PMID:22202117 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of HIPK2 protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in decreased expression of HIPK2 protein]
[Doxorubicin co-treated with zinc chloride] results in increased expression of HIPK2 mRNA
CTD PMID:19714248 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HK2 mRNA] CTD PMID:22202117 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO zinc chloride results in increased expression of HMOX1 mRNA; zinc chloride results in increased expression of HMOX1 protein
HMOX1 enhancer affects the reaction [zinc chloride results in increased expression of HMOX1 mRNA]
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HMOX1 mRNA]
CTD PMID:7538129, PMID:16870260, PMID:22202117, PMID:27427241 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO zinc chloride results in increased expression of HSPA1A mRNA CTD PMID:12085988, PMID:16870260 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO zinc chloride results in increased expression of HSPA1B mRNA CTD PMID:12085988 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP zinc chloride results in increased expression of HSPD1 protein CTD PMID:19429256 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Ifng interferon gamma multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of IFNG mRNA; zinc chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779, PMID:31588059 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta decreases expression ISO zinc chloride results in decreased expression of IKBKB mRNA CTD PMID:21540303 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 increases expression ISO zinc chloride results in increased expression of IL10 mRNA CTD PMID:24284788 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il10rb interleukin 10 receptor subunit beta decreases expression ISO zinc chloride results in decreased expression of IL10RB mRNA CTD PMID:19428942 NCBI chr11:31,560,301...31,582,457
Ensembl chr11:31,560,530...31,582,457
JBrowse link
G Il12b interleukin 12B decreases expression ISO zinc chloride results in decreased expression of IL12B mRNA CTD PMID:24284788 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il18r1 interleukin 18 receptor 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of IL18R1 mRNA] CTD PMID:22202117 NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO zinc chloride results in increased expression of IL1A protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]
CTD PMID:18509044 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
zinc chloride results in increased expression of IL1B mRNA
zinc chloride inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
CTD PMID:9138684, PMID:18509044, PMID:19130485, PMID:27427241 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO zinc chloride results in increased expression of IL1RL1 mRNA CTD PMID:19000923 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO zinc chloride results in increased expression of IL1RN mRNA CTD PMID:19428942 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il3 interleukin 3 multiple interactions
increases expression
ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein] CTD PMID:18509044 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il36rn interleukin 36 receptor antagonist decreases expression ISO zinc chloride results in decreased expression of IL36RN mRNA CTD PMID:19428942 NCBI chr 3:1,385,256...1,392,275
Ensembl chr 3:1,385,654...1,392,275
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
increases expression
ISO zinc chloride results in increased secretion of IL6 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of IL6 protein]; Thiourea inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]
zinc chloride results in increased expression of IL6 mRNA
CTD PMID:21842098, PMID:27427241 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insig2 insulin induced gene 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of INSIG2 mRNA] CTD PMID:22202117 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Insr insulin receptor increases phosphorylation ISO zinc chloride results in increased phosphorylation of INSR protein CTD PMID:11340092 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression ISO zinc chloride results in increased expression of IREB2 mRNA CTD PMID:18947441 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Itgb6 integrin subunit beta 6 increases expression ISO zinc chloride results in increased expression of ITGB6 mRNA CTD PMID:16870260 NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO zinc chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [zinc chloride results in increased expression of JUN mRNA]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
CTD PMID:11306679, PMID:19000923, PMID:21540303, PMID:30768131 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO zinc chloride results in increased expression of JUNB mRNA CTD PMID:19000923 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kat5 lysine acetyltransferase 5 multiple interactions ISO zinc chloride affects the reaction [4-aminophenylarsenoxide binds to KAT5 protein] CTD PMID:28837777 NCBI chr 1:220,967,795...220,974,596
Ensembl chr 1:220,967,796...220,974,597
JBrowse link
G Kdm3a lysine demethylase 3A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of KDM3A mRNA] CTD PMID:22202117 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kdm4b lysine demethylase 4B multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of KDM4B mRNA] CTD PMID:22202117 NCBI chr 9:10,656,035...10,734,127
Ensembl chr 9:10,653,216...10,734,073
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 affects folding
multiple interactions
ISO zinc chloride affects the folding of KEAP1 protein
zinc chloride promotes the reaction [KEAP1 protein binds to KEAP1 protein]
CTD PMID:30261176 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kif5a kinesin family member 5A multiple interactions
decreases activity
ISO Adenosine Triphosphate inhibits the reaction [zinc chloride results in decreased activity of KIF5A protein]; Magnesium Chloride affects the reaction [zinc chloride results in decreased activity of KIF5A protein] CTD PMID:28122263 NCBI chr 7:70,515,832...70,552,897
Ensembl chr 7:70,513,343...70,556,827
JBrowse link
G Lep leptin increases expression ISO zinc chloride results in increased expression of LEP mRNA CTD PMID:21540303 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Limch1 LIM and calponin homology domains 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of LIMCH1 mRNA] CTD PMID:22202117 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843
JBrowse link
G Lta lymphotoxin alpha decreases expression
increases expression
ISO zinc chloride results in decreased expression of LTA mRNA
zinc chloride results in increased expression of LTA mRNA
CTD PMID:19428942, PMID:21540303 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Ltb4r leukotriene B4 receptor decreases expression ISO zinc chloride results in decreased expression of LTB4R mRNA CTD PMID:19428942 NCBI chr15:34,449,299...34,453,352
Ensembl chr15:34,452,116...34,453,171
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of MAFF mRNA] CTD PMID:22202117 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO zinc chloride results in increased expression of MAFG mRNA CTD PMID:11162468 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Maml1 mastermind-like transcriptional coactivator 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of MAML1 mRNA CTD PMID:31588059 NCBI chr10:35,765,196...35,801,375
Ensembl chr10:35,765,719...35,800,120
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 increases activity ISO zinc chloride results in increased activity of MAP2K4 protein CTD PMID:11306679 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 multiple interactions
increases activity
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAP3K1 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAP3K1 protein] CTD PMID:11306679 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
EXP
ISO
N,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein
zinc chloride results in increased activity of MAPK1 protein
CTD PMID:11306679, PMID:11551972, PMID:16960431, PMID:20412391 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; N,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; Vanadates promotes the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16960431, PMID:20412391, PMID:21575692 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]; [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; Acetylcysteine inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]; RAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]; zinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:11306679, PMID:20423716, PMID:30768131 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO zinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK9 protein] CTD PMID:20423716 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression ISO zinc chloride results in increased expression of MCM3 mRNA CTD PMID:19000923 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mif macrophage migration inhibitory factor decreases expression ISO zinc chloride results in decreased expression of MIF mRNA CTD PMID:18947441 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir130a microRNA 130a multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR130A mRNA CTD PMID:22415087 NCBI chr 3:72,141,037...72,141,124
Ensembl chr 3:72,141,037...72,141,124
JBrowse link
G Mir223 microRNA 223 multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR223 mRNA CTD PMID:22415087 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mir29a microRNA 29a multiple interactions ISO [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR29A mRNA CTD PMID:22415087 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein] CTD PMID:21573219 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO zinc chloride results in decreased expression of MMP7 mRNA CTD PMID:21540303 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mt1 metallothionein 1 affects binding
increases expression
multiple interactions
affects response to substance
decreases expression
ISO
EXP
zinc chloride binds to MT1 protein
zinc chloride results in increased expression of MT1A mRNA; zinc chloride results in increased expression of MT1A protein
zinc chloride promotes the reaction [Glucose results in increased expression of MT1A mRNA]
MT1 affects the susceptibility to zinc chloride
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; bisindolylmaleimide I inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Dicumarol inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]; Genistein inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Ro 31-8220 inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Sodium Selenite inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; wortmannin inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]
zinc chloride results in increased expression of MT1 mRNA; zinc chloride results in increased expression of MT1 protein
zinc chloride results in decreased expression of MT1 protein
CTD PMID:3422486, PMID:8928928, PMID:11551972, PMID:14998373, PMID:15288509, PMID:16987576, PMID:17637929, PMID:17910954, PMID:19835899, PMID:23056475, PMID:24284788 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions
affects binding
affects response to substance
increases expression
ISO
EXP
[zinc chloride co-treated with pyrithione zinc] results in increased expression of MT2A mRNA; Dactinomycin inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; zinc chloride inhibits the reaction [Lipopolysaccharides results in increased expression of MT2A mRNA]
zinc chloride promotes the reaction [Cadmium Chloride results in increased expression of MT2 mRNA]
zinc chloride binds to MT2 protein
MT2 affects the susceptibility to zinc chloride
zinc chloride results in increased expression of MT2 mRNA; zinc chloride results in increased expression of MT2 protein
zinc chloride results in increased expression of MT2A mRNA; zinc chloride results in increased expression of MT2A protein
zinc chloride promotes the reaction [Glucose results in increased expression of MT2A mRNA]
CTD PMID:9138684, PMID:15288509, PMID:16842966, PMID:16870260, PMID:16987576, PMID:17234632, PMID:17637929, PMID:18947441, PMID:19835899, PMID:20471814, PMID:20801194, PMID:23056475 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 increases expression ISO zinc chloride results in increased expression of MT3 mRNA CTD PMID:18947441 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mta2 metastasis associated 1 family, member 2 decreases expression ISO zinc chloride results in decreased expression of MTA2 mRNA CTD PMID:16870260 NCBI chr 1:225,140,863...225,149,584
Ensembl chr 1:225,140,863...225,149,583
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions
affects localization
decreases expression
ISO zinc chloride results in increased phosphorylation of and results in increased activity of MTF1 protein
zinc chloride affects the localization of MTF1 protein
zinc chloride results in decreased expression of MTF1 mRNA
CTD PMID:11551972, PMID:16423564, PMID:18947441 NCBI chr 5:142,797,340...142,843,896
Ensembl chr 5:142,797,366...142,842,122
JBrowse link
G Mtf2 metal response element binding transcription factor 2 decreases expression ISO zinc chloride results in decreased expression of MTF2 mRNA CTD PMID:18947441 NCBI chr14:2,656,776...2,701,027
Ensembl chr14:2,658,267...2,700,977
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases response to substance
ISO NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]
NCF1 results in increased susceptibility to zinc chloride
CTD PMID:18509044 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of NDRG1 mRNA] CTD PMID:22202117 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Ndufaf5 NADH:ubiquinone oxidoreductase complex assembly factor 5 decreases expression ISO zinc chloride results in decreased expression of NDUFAF5 mRNA CTD PMID:16870260 NCBI chr 3:133,232,412...133,261,932
Ensembl chr 3:133,232,432...133,261,973
JBrowse link
G Nf2 neurofibromin 2 decreases expression ISO zinc chloride results in decreased expression of NF2 mRNA CTD PMID:16870260 NCBI chr14:84,996,905...85,088,547
Ensembl chr14:84,996,905...85,088,523
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects response to substance
multiple interactions
ISO [NFE2L2 affects the susceptibility to sulforafan] which affects the susceptibility to zinc chloride
zinc chloride promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]
CTD PMID:18385089, PMID:19303893 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases activity ISO zinc chloride results in increased activity of NFKB1 protein CTD PMID:21842098 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nip7 nucleolar pre-rRNA processing protein NIP7 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of NIP7 mRNA] CTD PMID:22202117 NCBI chr19:39,257,586...39,259,728
Ensembl chr19:39,257,586...39,259,728
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of NMNAT1 mRNA CTD PMID:31588059 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO zinc chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nox4 NADPH oxidase 4 increases expression ISO zinc chloride results in increased expression of NOX4 mRNA CTD PMID:16870260 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Ntn3 netrin 3 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of NTN3 mRNA CTD PMID:31588059 NCBI chr10:13,577,725...13,580,821
Ensembl chr10:13,577,725...13,580,821
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO zinc chloride results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G P2rx2 purinergic receptor P2X 2 multiple interactions EXP zinc chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr12:52,397,666...52,401,005
Ensembl chr12:52,397,792...52,401,015
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of P4HA1 mRNA] CTD PMID:22202117 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of P4HA2 mRNA] CTD PMID:22202117 NCBI chr10:39,435,227...39,464,134
Ensembl chr10:39,435,227...39,464,188
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO zinc chloride results in decreased expression of PAIP1 mRNA CTD PMID:18947441 NCBI chr 2:52,300,921...52,328,212
Ensembl chr 2:52,301,798...52,328,205
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
increases activity
increases response to substance
ISO zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]; zinc chloride inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]
zinc chloride results in increased expression of PARP1 protein
zinc chloride results in increased activity of PARP1 protein
PARP1 results in increased susceptibility to zinc chloride
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; Cibacron Blue F 3GA inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; coomassie Brilliant Blue inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; periodate-oxidized adenosine 5'-triphosphate inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]
CTD PMID:18509044, PMID:19056730, PMID:19714248, PMID:22253048 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 increases expression ISO zinc chloride results in increased expression of PCBD1 mRNA CTD PMID:18947441 NCBI chr20:30,689,690...30,696,465
Ensembl chr20:30,690,810...30,696,476
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Cadmium Chloride co-treated with zinc chloride] results in increased expression of PCNA protein CTD PMID:15602745 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdap1 PDGFA associated protein 1 multiple interactions ISO zinc chloride promotes the reaction [Cadmium Chloride results in increased expression of PDAP1 mRNA] CTD PMID:16842966 NCBI chr12:11,240,775...11,251,002
Ensembl chr12:11,240,761...11,251,004
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] CTD PMID:22202117 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO zinc chloride results in decreased expression of PEG3 mRNA CTD PMID:16870260 NCBI chr 1:70,210,810...70,237,450
Ensembl chr 1:70,222,964...70,237,443
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB3 mRNA] CTD PMID:22202117 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB4 mRNA] CTD PMID:22202117 NCBI chr 8:117,733,347...117,776,525
Ensembl chr 8:117,737,117...117,775,386
JBrowse link
G Pgf placental growth factor increases expression ISO zinc chloride results in increased expression of PGF mRNA CTD PMID:16870260 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PGK1 mRNA] CTD PMID:22202117 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Pgm1 phosphoglucomutase 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PGM1 mRNA] CTD PMID:22202117 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression ISO zinc chloride results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma multiple interactions ISO PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAP3K1 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 increases expression ISO zinc chloride results in increased expression of PIK3R4 mRNA CTD PMID:16870260 NCBI chr 8:114,300,248...114,350,686
Ensembl chr 8:114,300,257...114,350,681
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO zinc chloride results in increased expression of PIK3R5 mRNA CTD PMID:19000923 NCBI chr10:55,013,686...55,078,986
Ensembl chr10:55,013,703...55,080,421
JBrowse link
G Pmp22 peripheral myelin protein 22 increases expression ISO zinc chloride results in increased expression of PMP22 mRNA CTD PMID:18947441 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
affects localization
EXP 1,3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]; 1,3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of PRKCA protein]; Glucose promotes the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]; Vanadates promotes the reaction [zinc chloride affects the localization of PRKCA protein]; zinc chloride affects the localization of and results in increased activity of PRKCA protein CTD PMID:20800666, PMID:21575692 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of PTH1R mRNA CTD PMID:19913120 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Rab20 RAB20, member RAS oncogene family multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RAB20 mRNA] CTD PMID:22202117 NCBI chr16:83,358,116...83,382,326
Ensembl chr16:83,358,116...83,382,326
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO RAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rad21 RAD21 cohesin complex component increases expression ISO zinc chloride results in increased expression of RAD21 mRNA CTD PMID:19000923 NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673
JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression ISO zinc chloride results in increased expression of RAD51AP1 mRNA CTD PMID:19000923 NCBI chr 4:159,469,803...159,482,869
Ensembl chr 4:159,469,804...159,482,869
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions
increases phosphorylation
EXP 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein] CTD PMID:21575692 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rangap1 RAN GTPase activating protein 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RANGAP1 mRNA] CTD PMID:22202117 NCBI chr 7:122,939,266...122,967,178
Ensembl chr 7:122,940,376...122,967,178
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RBPJ mRNA] CTD PMID:22202117 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs multiple interactions ISO zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein] CTD PMID:21573219 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
ISO zinc chloride results in increased phosphorylation of RELA protein
RELA protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of IL6 protein]
CTD PMID:27427241 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rif1 replication timing regulatory factor 1 increases expression ISO zinc chloride results in increased expression of RIF1 mRNA CTD PMID:19000923 NCBI chr 3:37,599,540...37,648,818
Ensembl chr 3:37,599,728...37,647,631
JBrowse link
G Riok3 RIO kinase 3 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RIOK3 mRNA] CTD PMID:22202117 NCBI chr18:3,565,166...3,590,739
Ensembl chr18:3,565,166...3,590,739
JBrowse link
G Rora RAR-related orphan receptor A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RORA mRNA] CTD PMID:22202117 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rpl11 ribosomal protein L11 decreases expression ISO zinc chloride results in decreased expression of RPL11 mRNA CTD PMID:18947441 NCBI chr 5:154,390,809...154,394,412
Ensembl chr 5:154,388,140...154,394,328
JBrowse link
G Rrp15 ribosomal RNA processing 15 homolog multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRP15 mRNA] CTD PMID:22202117 NCBI chr13:105,155,824...105,178,907
Ensembl chr13:105,155,441...105,179,095
JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRS1 mRNA] CTD PMID:22202117 NCBI chr 5:9,430,710...9,432,343
Ensembl chr 5:9,430,728...9,432,343
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of RUNX2 protein; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 protein CTD PMID:19913120 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RUVBL1 mRNA] CTD PMID:22202117 NCBI chr 4:120,411,917...120,447,458
Ensembl chr 4:120,411,991...120,447,455
JBrowse link
G Sall1 spalt-like transcription factor 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of SALL1 mRNA CTD PMID:31588059 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
G Sap30 Sin3A associated protein 30 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SAP30 mRNA] CTD PMID:22202117 NCBI chr16:36,115,942...36,121,310
Ensembl chr16:36,116,258...36,121,097
JBrowse link
G Sbno1 strawberry notch homolog 1 increases expression ISO zinc chloride results in increased expression of SBNO1 mRNA CTD PMID:16870260 NCBI chr12:37,593,692...37,650,761
Ensembl chr12:37,593,874...37,649,036
JBrowse link
G Scara3 scavenger receptor class A, member 3 decreases expression ISO zinc chloride results in decreased expression of SCARA3 mRNA CTD PMID:16870260 NCBI chr15:42,605,505...42,638,409
Ensembl chr15:42,605,473...42,638,392
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO zinc chloride results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SCD mRNA] CTD PMID:22202117 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Selplg selectin P ligand increases expression ISO zinc chloride results in increased expression of SELPLG mRNA CTD PMID:21540303 NCBI chr12:48,577,905...48,579,196
Ensembl chr12:48,577,905...48,579,196
JBrowse link
G Sertad2 SERTA domain containing 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SERTAD2 mRNA] CTD PMID:22202117 NCBI chr14:104,786,649...104,890,022
Ensembl chr14:104,821,215...104,886,197
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 multiple interactions
increases expression
EXP [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK2 protein] CTD PMID:25007851 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions
increases expression
EXP [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK3 protein] CTD PMID:25007851 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases transport ISO SLC11A2 protein results in increased transport of zinc chloride CTD PMID:22736759 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc16a3 solute carrier family 16 member 3 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SLC16A3 mRNA] CTD PMID:22202117 NCBI chr10:110,138,519...110,148,360
Ensembl chr10:110,138,586...110,148,358
JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions ISO [Kainic Acid co-treated with zinc chloride] results in decreased expression of SLC1A2 protein CTD PMID:19061913 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO zinc chloride results in decreased expression of SLC1A5 mRNA CTD PMID:18947441 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc25a15 solute carrier family 25 member 15 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of SLC25A15 mRNA] CTD PMID:22202117 NCBI chr16:74,505,318...74,554,523
Ensembl chr16:74,531,564...74,554,529
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases expression
ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SLC2A1 mRNA]
zinc chloride results in increased expression of SLC2A1 mRNA
CTD PMID:19000923, PMID:22202117 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions
increases expression
ISO
EXP
epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of SLC30A1 mRNA]; zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in decreased expression of SLC30A1 mRNA]
zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A1 mRNA]; zinc chloride promotes the reaction [Glucose results in increased expression of SLC30A1 mRNA]
CTD PMID:18947441, PMID:20392624, PMID:20471814, PMID:23056475, PMID:25653005 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc30a2 solute carrier family 30 member 2 increases expression
multiple interactions
EXP zinc chloride results in increased expression of SLC30A2 mRNA
zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A2 mRNA]
CTD PMID:20392624, PMID:25653005 NCBI chr 5:152,559,577...152,571,800
Ensembl chr 5:152,559,577...152,571,799
JBrowse link
G Slc30a4 solute carrier family 30 member 4 multiple interactions EXP zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A4 mRNA] CTD PMID:25653005 NCBI chr 3:114,805,919...114,828,154
Ensembl chr 3:114,805,922...114,828,154
JBrowse link
G Slc30a5 solute carrier family 30 member 5 decreases expression
multiple interactions
ISO zinc chloride results in decreased expression of SLC30A5 mRNA
Dactinomycin inhibits the reaction [zinc chloride results in decreased expression of SLC30A5 mRNA]
CTD PMID:17234632, PMID:20392624 NCBI chr 2:30,815,683...30,845,796
Ensembl chr 2:30,815,703...30,846,149
JBrowse link
G Slc30a7 solute carrier family 30 member 7 increases expression
decreases expression
ISO zinc chloride results in increased expression of SLC30A7 mRNA
zinc chloride results in decreased expression of SLC30A7 mRNA
CTD PMID:20392624 NCBI chr 2:218,888,431...218,951,030
Ensembl chr 2:218,888,431...218,951,030
JBrowse link
G Slc31a2 solute carrier family 31 member 2 increases expression
decreases expression
ISO zinc chloride results in increased expression of SLC31A2 mRNA
zinc chloride results in decreased expression of SLC31A2 mRNA
CTD PMID:18947441 NCBI chr 5:78,120,606...78,131,111
Ensembl chr 5:78,120,607...78,131,114
JBrowse link
G Slc39a1 solute carrier family 39 member 1 multiple interactions ISO zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A1 mRNA] CTD PMID:20471814 NCBI chr 2:189,609,766...189,615,367
Ensembl chr 2:189,609,800...189,615,366
JBrowse link
G Slc39a2 solute carrier family 39 member 2 multiple interactions
increases expression
ISO [SLC39A2 protein co-treated with zinc chloride] results in increased abundance of Glutathione; zinc chloride promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]; zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLC mRNA]; zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA]
zinc chloride results in increased expression of SLC39A2 mRNA
CTD PMID:18385089 NCBI chr15:28,295,044...28,297,688
Ensembl chr15:28,295,368...28,297,684
JBrowse link
G Slc39a3 solute carrier family 39 member 3 multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A3 mRNA] CTD PMID:25653005 NCBI chr 7:11,545,073...11,551,074
Ensembl chr 7:11,545,024...11,553,370
JBrowse link
G Slc39a4 solute carrier family 39 member 4 multiple interactions
decreases expression
ISO
EXP
zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A4 mRNA]
zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A4 mRNA]
zinc chloride results in decreased expression of SLC39A4 mRNA
CTD PMID:20471814, PMID:25653005 NCBI chr 7:117,675,718...117,682,586
Ensembl chr 7:117,675,720...117,680,004
JBrowse link
G Slc39a8 solute carrier family 39 member 8 multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A8 mRNA] CTD PMID:25653005 NCBI chr 2:241,028,851...241,092,584
Ensembl chr 2:241,029,693...241,092,582
JBrowse link
G Slc48a1 solute carrier family 48 member 1 increases expression ISO zinc chloride results in increased expression of SLC48A1 mRNA CTD PMID:16870260 NCBI chr 7:139,271,698...139,279,499
Ensembl chr 7:139,271,698...139,279,499
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A1 mRNA] CTD PMID:20060848 NCBI chr14:82,910,448...82,975,303
Ensembl chr14:82,909,981...82,975,263
JBrowse link
G Slc5a2 solute carrier family 5 member 2 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP110 protein binds to and affects the expression of SLC5A2 promoter]]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A2 mRNA] CTD PMID:20060848 NCBI chr 1:199,682,688...199,688,809
Ensembl chr 1:199,682,688...199,688,809
JBrowse link
G Slc9a1 solute carrier family 9 member A1 increases expression ISO zinc chloride results in increased expression of SLC9A1 mRNA CTD PMID:18947441 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of SORD protein] CTD PMID:18972399 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
increases activity
ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]]
zinc chloride results in increased activity of SP1 protein
CTD PMID:9330853, PMID:20060848 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sp110 SP110 nuclear body protein multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP110 protein binds to and affects the expression of SLC5A2 promoter]] CTD PMID:20060848 NCBI chr 9:92,593,909...92,618,867
Ensembl chr 9:92,593,910...92,616,165
JBrowse link
G Spag4 sperm associated antigen 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SPAG4 mRNA] CTD PMID:22202117 NCBI chr 3:151,609,602...151,613,946
Ensembl chr 3:151,609,602...151,613,942
JBrowse link
G Spice1 spindle and centriole associated protein 1 decreases expression ISO zinc chloride results in decreased expression of SPICE1 mRNA CTD PMID:16870260 NCBI chr11:61,250,649...61,294,116
Ensembl chr11:61,251,696...61,294,022
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression ISO zinc chloride results in decreased expression of SPINK1 mRNA CTD PMID:18947441 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SPOCK1 mRNA] CTD PMID:22202117 NCBI chr17:7,675,531...7,797,863
Ensembl chr17:7,675,531...7,797,863
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression
multiple interactions
ISO zinc chloride results in decreased expression of SPP1 mRNA
[zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of SPP1 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SPP1 mRNA; zinc chloride promotes the reaction [Calcitriol results in increased activity of SPP1 promoter]
CTD PMID:10777672, PMID:19428942, PMID:19913120 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases phosphorylation
EXP 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]; Vanadates promotes the reaction [zinc chloride results in increased phosphorylation of SRC protein] CTD PMID:12211081, PMID:21575692 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srm spermidine synthase multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of SRM mRNA] CTD PMID:22202117 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
G Stbd1 starch binding domain 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of STBD1 mRNA] CTD PMID:22202117 NCBI chr14:16,976,355...16,979,760
Ensembl chr14:16,976,356...16,979,760
JBrowse link
G Stmn1 stathmin 1 increases expression ISO zinc chloride results in increased expression of STMN1 mRNA CTD PMID:19000923 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions ISO [Citric Acid co-treated with zinc chloride] results in decreased activity of TERT protein CTD PMID:16624386 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tf transferrin multiple interactions
increases expression
ISO zinc chloride inhibits the reaction [TF protein results in increased uptake of Iron]
zinc chloride results in increased expression of TF mRNA
CTD PMID:11335103, PMID:18947441 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO zinc chloride results in increased expression of TFPI2 mRNA CTD PMID:16870260 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
JBrowse link
G Tfrc transferrin receptor increases expression ISO zinc chloride results in increased expression of TFRC mRNA CTD PMID:19000923 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tmem45a transmembrane protein 45A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of TMEM45A mRNA] CTD PMID:22202117 NCBI chr11:46,009,216...46,093,969
Ensembl chr11:46,009,322...46,093,973
JBrowse link
G Tnf tumor necrosis factor increases expression ISO zinc chloride results in increased expression of TNF mRNA CTD PMID:19428942, PMID:21540303, PMID:24284788 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of TNFRSF11B protein] CTD PMID:23726800 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions EXP zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of TNFSF11 protein] CTD PMID:23726800 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tnfsf14 TNF superfamily member 14 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of TNFSF14 mRNA CTD PMID:31588059 NCBI chr 9:9,761,363...9,765,461
Ensembl chr 9:9,761,536...9,765,186
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]] CTD PMID:19714248 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tra2a transformer 2 alpha homolog decreases expression ISO zinc chloride results in decreased expression of TRA2A mRNA CTD PMID:16870260 NCBI chr 4:78,905,380...78,924,203
Ensembl chr 4:78,905,380...78,924,181
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Ttr transthyretin multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of TTR mRNA CTD PMID:31588059 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Tuba1b tubulin, alpha 1B increases expression ISO zinc chloride results in increased expression of TUBA1B mRNA CTD PMID:18947441 NCBI chr 7:140,614,746...140,617,721
Ensembl chr 7:140,614,752...140,617,721
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO zinc chloride promotes the reaction [Dimethyldithiocarbamate results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; zinc chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:1,723,135...1,745,147
Ensembl chr  X:1,723,174...1,741,701
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 increases expression ISO zinc chloride results in increased expression of UBE2E2 mRNA CTD PMID:18947441 NCBI chr15:7,402,210...7,928,320
Ensembl chr15:7,871,497...7,927,939
JBrowse link
G Unc5b unc-5 netrin receptor B increases expression ISO zinc chloride results in increased expression of UNC5B mRNA CTD PMID:18947441 NCBI chr20:30,339,680...30,406,593
Ensembl chr20:30,339,673...30,406,295
JBrowse link
G Use1 unconventional SNARE in the ER 1 increases expression ISO zinc chloride results in increased expression of USE1 mRNA CTD PMID:16870260 NCBI chr16:19,762,202...19,765,781
Ensembl chr16:19,762,938...19,765,782
JBrowse link
G Utrn utrophin affects binding ISO zinc chloride binds to UTRN protein CTD PMID:17009962 NCBI chr 1:6,451,809...6,970,040
Ensembl chr 1:6,451,810...6,970,040
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of VEGFA mRNA]
CTD PMID:19714248 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wdr4 WD repeat domain 4 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of WDR4 mRNA] CTD PMID:22202117 NCBI chr20:10,240,571...10,264,818
Ensembl chr20:10,239,154...10,257,044
JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of WSB1 mRNA] CTD PMID:22202117 NCBI chr10:66,586,905...66,602,984
Ensembl chr10:66,586,924...66,602,987
JBrowse link
G Xcr1 X-C motif chemokine receptor 1 decreases expression ISO zinc chloride results in decreased expression of XCR1 mRNA CTD PMID:19428942 NCBI chr 8:132,911,474...132,919,110
Ensembl chr 8:132,911,486...132,919,110
JBrowse link
G Yeats2 YEATS domain containing 2 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of YEATS2 mRNA] CTD PMID:22202117 NCBI chr11:84,330,064...84,595,296
Ensembl chr11:84,330,064...84,583,542
JBrowse link
G Zfp292 zinc finger protein 292 multiple interactions ISO zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ZNF292 mRNA] CTD PMID:22202117 NCBI chr 5:50,282,084...50,362,344
Ensembl chr 5:50,282,084...50,362,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        biochemical role 19313
          enzyme inhibitor 18173
            EC 5.* (isomerase) inhibitor 6636
              EC 5.3.* (intramolecular oxidoreductase) inhibitor 550
                EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor + 0
                EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor + 550
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.