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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 2.6.* (nitrogenous group transferase) inhibitor
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Accession:CHEBI:76665 term browser browse the term
Definition:A transferase inhibitor that inhibits a nitrogenous group transferase (EC 2.6.*.*).
Synonyms:related_synonym: EC 2.6.* inhibitor;   EC 2.6.* inhibitors;   nitrogenous group transferase (EC 2.6.*) inhibitors;   nitrogenous group transferase inhibitor;   nitrogenous group transferase inhibitors


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(aminooxy)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase decreases activity EXP Aminooxyacetic Acid results in decreased activity of ABAT protein CTD PMID:3933514 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein CTD PMID:25321483 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Dld dihydrolipoamide dehydrogenase multiple interactions EXP Aminooxyacetic Acid inhibits the reaction [S-(1,1,2,2-tetrafluoroethyl)cysteine results in decreased activity of DLD protein]; Aminooxyacetic Acid inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in decreased activity of DLD protein] CTD PMID:2360207 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Aminooxyacetic Acid co-treated with Xylitol] results in increased expression of G6PC1 mRNA CTD PMID:31974165 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gad2 glutamate decarboxylase 2 decreases activity EXP Aminooxyacetic Acid results in decreased activity of GAD2 protein CTD PMID:12634427 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions ISO [GLUD1 protein co-treated with Ketoglutaric Acids co-treated with NADP co-treated with Aminooxyacetic Acid] affects the reaction [Carbon Tetrachloride affects the abundance of Ammonia]; dipicolinic acid inhibits the reaction [[GLUD1 protein co-treated with Ketoglutaric Acids co-treated with NADP co-treated with Aminooxyacetic Acid] affects the reaction [Carbon Tetrachloride affects the abundance of Ammonia]] CTD PMID:26639393 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 multiple interactions ISO [Aminooxyacetic Acid co-treated with Xylitol] results in increased expression of GPD2 mRNA; [GPD2 mutant form co-treated with Aminooxyacetic Acid] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; [Potassium Chloride co-treated with Diazoxide] inhibits the reaction [[GPD2 mutant form co-treated with Aminooxyacetic Acid] inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:10199125 PMID:10464266 PMID:31974165 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Aminooxyacetic Acid inhibits the reaction [N-acetyl-S-pentachloro-1,3-butadienylcysteine results in decreased activity of GSR protein] CTD PMID:2360207 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO [GPD2 mutant form co-treated with Aminooxyacetic Acid] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; [Potassium Chloride co-treated with Diazoxide] inhibits the reaction [[GPD2 mutant form co-treated with Aminooxyacetic Acid] inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:10199125 PMID:10464266 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [Aminooxyacetic Acid co-treated with Xylitol] results in increased expression of MLXIPL mRNA alternative form CTD PMID:31974165 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form CTD PMID:25321483 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 decreases activity EXP Aminooxyacetic Acid results in decreased activity of SLC6A12 protein CTD PMID:12634427 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
vigabatrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase decreases activity EXP Vigabatrin results in decreased activity of AADAT protein CTD PMID:16765940 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Abat 4-aminobutyrate aminotransferase multiple interactions
decreases activity		 ISO
EXP		 [Vigabatrin results in decreased activity of ABAT protein] which results in increased abundance of gamma-Aminobutyric Acid CTD PMID:3933514 PMID:10951220 PMID:11468302 PMID:12748807 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Ddc dopa decarboxylase decreases expression EXP Vigabatrin results in decreased expression of DDC mRNA CTD PMID:8717341 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 increases expression ISO Vigabatrin results in increased expression of FMR1 protein CTD PMID:21490592 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression EXP Vigabatrin results in increased expression of GAD1 protein CTD PMID:11673025 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gnat2 G protein subunit alpha transducin 2 increases response to substance ISO GNAT2 results in increased susceptibility to Vigabatrin CTD PMID:22970106 NCBI chr 2:195,726,371...195,735,866
Ensembl chr 2:195,726,762...195,735,866 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases activity EXP Vigabatrin results in decreased activity of KYAT1 protein CTD PMID:16765940 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase increases response to substance ISO MTHFR results in increased susceptibility to Vigabatrin CTD PMID:21490592 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Pde6g phosphodiesterase 6G increases response to substance ISO PDE6G results in increased susceptibility to Vigabatrin CTD PMID:22970106 NCBI chr10:105,721,502...105,726,150
Ensembl chr10:105,721,682...105,726,719 		JBrowse link
G Reln reelin increases expression ISO Vigabatrin results in increased expression of RELN protein CTD PMID:21490592 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    role 19875
      biological role 19873
        biochemical role 19567
          enzyme inhibitor 18735
            EC 2.* (transferase) inhibitor 14786
              EC 2.6.* (nitrogenous group transferase) inhibitor 21
                EC 2.6.1.* (transaminase) inhibitor + 21
paths to the root