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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 2.6.* (nitrogenous group transferase) inhibitor
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Accession:CHEBI:76665 term browser browse the term
Definition:A transferase inhibitor that inhibits a nitrogenous group transferase (EC 2.6.*.*).
Synonyms:related_synonym: EC 2.6.* inhibitor;   EC 2.6.* inhibitors;   nitrogenous group transferase (EC 2.6.*) inhibitors;   nitrogenous group transferase inhibitor;   nitrogenous group transferase inhibitors


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vigabatrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase decreases activity EXP Vigabatrin results in decreased activity of AADAT protein CTD PMID:16765940 NCBI chr16:32,832,001...32,868,680
Ensembl chr16:32,832,061...32,868,702
JBrowse link
G Abat 4-aminobutyrate aminotransferase multiple interactions
decreases activity
ISO
EXP
[Vigabatrin results in decreased activity of ABAT protein] which results in increased abundance of gamma-Aminobutyric Acid CTD PMID:3933514, PMID:10951220, PMID:11468302, PMID:12748807 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Ddc dopa decarboxylase decreases expression EXP Vigabatrin results in decreased expression of DDC mRNA CTD PMID:8717341 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Fmr1 FMRP translational regulator 1 increases expression ISO Vigabatrin results in increased expression of FMR1 protein CTD PMID:21490592 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression EXP Vigabatrin results in increased expression of GAD1 protein CTD PMID:11673025 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gnat2 G protein subunit alpha transducin 2 increases response to substance ISO GNAT2 results in increased susceptibility to Vigabatrin CTD PMID:22970106 NCBI chr 2:210,880,754...210,890,765
Ensembl chr 2:210,880,777...210,889,881
JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases activity EXP Vigabatrin results in decreased activity of KYAT1 protein CTD PMID:16765940 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Mthfr methylenetetrahydrofolate reductase increases response to substance ISO MTHFR results in increased susceptibility to Vigabatrin CTD PMID:21490592 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Pde6g phosphodiesterase 6G increases response to substance ISO PDE6G results in increased susceptibility to Vigabatrin CTD PMID:22970106 NCBI chr10:109,620,499...109,625,214
Ensembl chr10:109,620,980...109,622,745
JBrowse link
G Reln reelin increases expression ISO Vigabatrin results in increased expression of RELN protein CTD PMID:21490592 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          enzyme inhibitor 18150
            EC 2.* (transferase) inhibitor 13811
              EC 2.6.* (nitrogenous group transferase) inhibitor 10
                EC 2.6.1.* (transaminase) inhibitor + 10
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.