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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chlorendic acid
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Accession:CHEBI:76603 term browser browse the term
Definition:A bridged organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with maleic anhydride followed by hydrolysis of the resulting anhydride. A chemical intermediate used in the preparation of fire-retardant polyester resins and plasticisers.
Synonyms:exact_synonym: 1,4,5,6,7,7-hexachlorobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid
 related_synonym: 1,4,5,6,7,7-Hexachloro-5-norbornene-2,3-dicarboxylic acid;   1,4,5,6,7,7-Hexachlorobicyclo(2.2.1)-5-heptene-2,3-dicarboxylic acid;   Formula=C9H4Cl6O4;   Hexachloro-endo-methylenetetrahydrophthalic acid;   InChI=1S/C9H4Cl6O4/c10-3-4(11)8(13)2(6(18)19)1(5(16)17)7(3,12)9(8,14)15/h1-2H,(H,16,17)(H,18,19);   InChIKey=DJKGDNKYTKCJKD-UHFFFAOYSA-N;   SMILES=OC(=O)C1C(C(O)=O)C2(Cl)C(Cl)=C(Cl)C1(Cl)C2(Cl)Cl
 xref: CAS:115-28-6;   KEGG:C19204
 xref_mesh: MESH:C035377
 xref: PMID:12748725;   PMID:1367592;   PMID:15318386;   PMID:18961903;   PMID:21089823;   PMID:21850124;   PMID:2197462;   PMID:22584684;   PMID:2629100;   PMID:7120517;   PMID:8792842;   Reaxys:1892213;   Reaxys:8156979;   Wikipedia:Chlorendic_acid



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chlorendic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C6 complement C6 decreases expression EXP chlorendic acid results in decreased expression of C6 mRNA CTD PMID:22584684 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G Ccnb1 cyclin B1 increases expression EXP chlorendic acid results in increased expression of CCNB1 mRNA CTD PMID:22584684 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP chlorendic acid results in increased expression of CCND1 mRNA CTD PMID:22584684 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP chlorendic acid results in increased expression of CDK1 mRNA CTD PMID:22584684 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression EXP chlorendic acid results in increased expression of CDKN3 mRNA CTD PMID:22584684 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases secretion
increases expression
ISO chlorendic acid results in increased secretion of ENPP2 protein
chlorendic acid results in increased expression of ENPP2 mRNA
CTD PMID:22952646 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Gjb1 gap junction protein, beta 1 multiple interactions EXP [Diethylnitrosamine co-treated with chlorendic acid] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with chlorendic acid] results in decreased expression of GJB1 protein CTD PMID:1973356 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Kif11 kinesin family member 11 increases expression EXP chlorendic acid results in increased expression of KIF11 mRNA CTD PMID:22584684 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Mir193a microRNA 193a decreases expression EXP chlorendic acid results in decreased expression of MIR193A mRNA CTD PMID:22584684 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454
JBrowse link
G Mir200a microRNA 200a increases expression EXP chlorendic acid results in increased expression of MIR200A mRNA CTD PMID:22584684 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir200b microRNA 200b increases expression EXP chlorendic acid results in increased expression of MIR200B mRNA CTD PMID:22584684 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
JBrowse link
G Mir20a microRNA 20a decreases expression EXP chlorendic acid results in decreased expression of MIR20A mRNA CTD PMID:22584684 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir28 microRNA 28 increases expression EXP chlorendic acid results in increased expression of MIR28 mRNA CTD PMID:22584684 NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608
JBrowse link
G Mir34a microRNA 34a increases expression EXP chlorendic acid results in increased expression of MIR34A mRNA CTD PMID:22584684 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mir3545 microRNA 3545 decreases expression EXP chlorendic acid results in decreased expression of MIR203 mRNA CTD PMID:22584684 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656
JBrowse link
G Mir429 microRNA 429 increases expression EXP chlorendic acid results in increased expression of MIR429 mRNA CTD PMID:22584684 NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543
JBrowse link
G Mir497 microRNA 497 decreases expression EXP chlorendic acid results in decreased expression of MIR497 mRNA CTD PMID:22584684 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
JBrowse link
G Mir96 microRNA 96 decreases expression EXP chlorendic acid results in decreased expression of MIR96 mRNA CTD PMID:22584684 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression EXP chlorendic acid results in decreased expression of NAMPT mRNA CTD PMID:22584684 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP chlorendic acid results in increased expression of NUPR1 mRNA CTD PMID:22584684 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions ISO chlorendic acid results in increased cleavage of and results in increased activity of PPP3CA protein CTD PMID:22952646 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Stmn1 stathmin 1 increases expression EXP chlorendic acid results in increased expression of STMN1 mRNA CTD PMID:22584684 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Tnf tumor necrosis factor increases expression ISO chlorendic acid results in increased expression of TNF mRNA CTD PMID:22952646 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP chlorendic acid results in increased expression of TOP2A mRNA CTD PMID:22584684 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression EXP chlorendic acid results in increased expression of TP53INP1 mRNA CTD PMID:22584684 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression EXP chlorendic acid results in increased expression of WEE1 mRNA CTD PMID:22584684 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link

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  CHEBI ontology 20050
    role 20001
      biological role 20000
        aetiopathogenetic role 19254
          carcinogenic agent 18533
            chlorendic acid 26
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic group 18937
                              organic divalent group 18922
                                organodiyl group 18922
                                  carbonyl group 18872
                                    carbonyl compound 18872
                                      dicarboxylic acids and O-substituted derivatives 10380
                                        dicarboxylic acid 10373
                                          chlorendic acid 26
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