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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-(chloromethyl)pyridine
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Accession:CHEBI:76601 term browser browse the term
Definition:An organochlorine compound that is pyridine substituted at position 2 by a chloromethyl group.
Synonyms:related_synonym: 2-Chloromethylpyridine;   2-Picolyl chloride;   Formula=C6H6ClN;   InChI=1S/C6H6ClN/c7-5-6-3-1-2-4-8-6/h1-4H,5H2;   InChIKey=NJWIMFZLESWFIM-UHFFFAOYSA-N;   SMILES=ClCc1ccccn1
 xref: CAS:4377-33-7
 xref_mesh: MESH:C091423
 xref: PMID:7529357;   Reaxys:107713
 cyclic_relationship: is_conjugate_base_of CHEBI:76602


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2-(chloromethyl)pyridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsm1 acyl-CoA synthetase medium-chain family member 1 increases expression ISO 2-chloromethylpyridine results in increased expression of ACSM1 mRNA CTD PMID:17311802 NCBI chr 1:189,359,374...189,395,277
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO 2-chloromethylpyridine results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO 2-chloromethylpyridine results in increased expression of AKR1C2 mRNA CTD PMID:26198647 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO 2-chloromethylpyridine results in increased expression of CES1 mRNA CTD PMID:17311802 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 2-chloromethylpyridine results in increased expression of GCLC mRNA CTD PMID:26198647 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 2-chloromethylpyridine results in increased expression of GCLM mRNA CTD PMID:26198647 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO 2-chloromethylpyridine results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO 2-chloromethylpyridine results in increased expression of GSR mRNA CTD PMID:26198647 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO 2-chloromethylpyridine results in increased activity of NFE2L2 protein CTD PMID:30114225, PMID:30203046 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 2-chloromethylpyridine results in increased expression of NQO1 mRNA CTD PMID:17311802 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Rras2 RAS related 2 increases expression ISO 2-chloromethylpyridine results in increased expression of RRAS2 mRNA CTD PMID:26198647 NCBI chr 1:178,940,515...179,010,257
Ensembl chr 1:178,940,516...179,010,257
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO 2-chloromethylpyridine results in increased expression of SLC7A11 mRNA CTD PMID:26198647 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO 2-chloromethylpyridine results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 2-chloromethylpyridine results in increased expression of SRXN1 mRNA CTD PMID:26198647 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      molecular entity 19784
        polyatomic entity 19697
          heteroatomic molecular entity 19622
            halide 17976
              organohalogen compound 17712
                organochlorine compound 17466
                  2-(chloromethyl)pyridine 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  organic heteromonocyclic compound 16445
                                    pyridines 8381
                                      2-(chloromethyl)pyridine 14
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