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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quercetin O-glycoside
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Accession:CHEBI:76424 term browser browse the term
Definition:Any glycosyloxyflavone that is an O-glycosylated derivative of quercetin.
Synonyms:related_synonym: quercetin O-glycosides


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miquelianin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] CTD PMID:26190035 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine binds to ADRB2 protein] CTD PMID:24929186 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agt angiotensinogen multiple interactions ISO quercetin 3-O-glucuronide analog inhibits the reaction [AGT protein results in increased phosphorylation of JUN protein] CTD PMID:12054679 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [ALOX5 protein results in increased chemical synthesis of Leukotriene B4] CTD PMID:18096136 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G App amyloid beta precursor protein multiple interactions
decreases expression
ISO quercetin 3-O-glucuronide inhibits the reaction [APP protein binds to APP protein modified form]
quercetin 3-O-glucuronide results in decreased expression of APP protein
CTD PMID:23097297 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Cat catalase multiple interactions EXP [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of CAT mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of CAT protein CTD PMID:25716194 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA] CTD PMID:27257344 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cd36 CD36 molecule decreases expression ISO quercetin 3-O-glucuronide results in decreased expression of CD36 mRNA CTD PMID:18199750 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA] CTD PMID:26190035 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in increased expression of FAS mRNA] CTD PMID:26190035 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of GCLC mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of GCLC protein CTD PMID:25716194 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP
quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of HMOX1 mRNA]
[quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of HMOX1 mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of HMOX1 protein
CTD PMID:24929186 PMID:25716194 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Lysophosphatidylcholines results in increased expression of ICAM1 mRNA] CTD PMID:27257344 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of IKBKB protein] CTD PMID:23504962 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] CTD PMID:26190035 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased secretion of IL6 protein] CTD PMID:23504962 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased chemical synthesis of Nitric Oxide]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]] CTD PMID:23504962 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of IRS1 protein] CTD PMID:23504962 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO quercetin 3-O-glucuronide analog inhibits the reaction [AGT protein results in increased phosphorylation of JUN protein] CTD PMID:12054679 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA] CTD PMID:24929186 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA] CTD PMID:24929186 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Msr1 macrophage scavenger receptor 1 decreases expression ISO quercetin 3-O-glucuronide results in decreased expression of MSR1 mRNA CTD PMID:18199750 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] CTD PMID:27257013 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]] CTD PMID:23504962 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in decreased expression of PPARA protein] CTD PMID:26190035 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO quercetin 3-O-glucuronide results in increased expression of PPARG mRNA CTD PMID:25765892 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein] CTD PMID:27257013 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of RELA protein] CTD PMID:23504962 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
increases uptake
ISO quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]
SLC22A8 protein results in increased uptake of quercetin 3-O-glucuronide analog
CTD PMID:21244849 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26190035 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
quercetin 3-O-glucuronide inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with TNF protein] results in increased expression of VCAM1 protein]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased secretion of TNF protein]
quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]
CTD PMID:17880982 PMID:23504962 PMID:26190035 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases activity ISO quercetin 3-O-glucuronide results in decreased activity of TNFSF11 protein CTD PMID:19495926 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with TNF protein] results in increased expression of VCAM1 protein] CTD PMID:17880982 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
quercetin 3-O-beta-D-galactopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases expression
multiple interactions
EXP hyperoside results in increased expression of ACHE mRNA
hyperoside results in increased expression of and results in increased activity of ACHE protein
CTD PMID:27019979 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
hyperoside inhibits the reaction [tert-Butylhydroperoxide affects the localization of BAX protein]
hyperoside inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]
CTD PMID:18552516 PMID:31326407 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:31326407 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 protein CTD PMID:24173369 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Quercetin co-treated with hyperoside] results in increased cleavage of CASP3 protein CTD PMID:24173369 PMID:25354548 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP cyclopamine inhibits the reaction [hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]]; hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein] CTD PMID:31326407 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO hyperoside inhibits the reaction [tert-Butylhydroperoxide affects the localization of CYCS protein] CTD PMID:18552516 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
ISO hyperoside results in decreased activity of CYP2E1 protein
hyperoside inhibits the reaction [Acetaminophen results in decreased activity of CYP2E1 protein]
CTD PMID:26772156 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO hyperoside inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:22613215 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gli1 GLI family zinc finger 1 multiple interactions
increases expression
EXP hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 protein]
hyperoside results in increased expression of GLI1 mRNA; hyperoside results in increased expression of GLI1 protein
CTD PMID:31326407 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO hyperoside inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:26772156 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:30125551 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:30125551 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mir21 microRNA 21 multiple interactions ISO [Quercetin co-treated with hyperoside] results in decreased expression of MIR21 mRNA; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA]; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein]; MIR21 mRNA results in decreased susceptibility to [Quercetin co-treated with hyperoside] CTD PMID:25354548 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir27a microRNA 27a multiple interactions ISO [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in decreased expression of ZBTB10 mRNA]; [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in increased expression of SP1 mRNA]; [Quercetin co-treated with hyperoside] results in decreased expression of MIR27A mRNA; MIR27A mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA] CTD PMID:24173369 NCBI chr19:25,318,736...25,318,822
Ensembl chr19:25,318,736...25,318,822
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization ISO hyperoside affects the localization of NFE2L2 protein CTD PMID:26772156 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:30125551 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Hyperoside increases expression of Nqo1 protein in liver RGD PMID:31399183 RGD:25823190 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Quercetin co-treated with hyperoside] results in increased cleavage of PARP1 protein CTD PMID:24173369 PMID:25354548 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pdcd4 programmed cell death 4 multiple interactions ISO [Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA; [Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA]; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein] CTD PMID:25354548 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP hyperoside results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr 6:127,075,954...127,127,985
Ensembl chr 6:127,075,954...127,127,413
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:30125551 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Shh sonic hedgehog signaling molecule increases expression
multiple interactions
EXP hyperoside results in increased expression of SHH mRNA; hyperoside results in increased expression of SHH protein
hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SHH mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SHH protein]
CTD PMID:31326407 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO hyperoside inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of SIRT1 protein] CTD PMID:18552516 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Smo smoothened, frizzled class receptor increases expression
multiple interactions
EXP hyperoside results in increased expression of SMO mRNA; hyperoside results in increased expression of SMO protein
hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SMO mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SMO protein]
CTD PMID:31326407 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in increased expression of SP1 mRNA]; [Quercetin co-treated with hyperoside] results in decreased expression of SP1 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP1 protein CTD PMID:24173369 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sp3 Sp3 transcription factor multiple interactions ISO [Quercetin co-treated with hyperoside] results in decreased expression of SP3 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP3 protein CTD PMID:24173369 NCBI chr 3:59,644,579...59,689,011
Ensembl chr 3:59,646,015...59,688,692
JBrowse link
G Sp4 Sp4 transcription factor multiple interactions ISO [Quercetin co-treated with hyperoside] results in decreased expression of SP4 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP4 protein CTD PMID:24173369 NCBI chr 6:146,135,877...146,201,344
Ensembl chr 6:146,135,877...146,195,819
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions
increases expression
ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of SULT2A1 mRNA]
hyperoside results in increased expression of SULT2A1 mRNA
CTD PMID:26772156 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:30125551 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein] CTD PMID:30125551 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions
increases expression
ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A1 mRNA]
hyperoside results in increased expression of UGT1A1 mRNA
CTD PMID:26772156 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A6 mRNA] CTD PMID:26772156 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 multiple interactions
increases expression
ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT2B1 mRNA]
hyperoside results in increased expression of UGT2B1 mRNA
CTD PMID:26772156 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:30125551 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 multiple interactions ISO [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in decreased expression of ZBTB10 mRNA]; [Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA; MIR27A mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA] CTD PMID:24173369 NCBI chr 2:94,692,939...94,730,976
Ensembl chr 2:94,692,939...94,730,978
JBrowse link
quercetin 3-O-beta-D-glucofuranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA CTD PMID:20033131 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Apoa1 apolipoprotein A1 increases secretion ISO isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Atf6 activating transcription factor 6 increases expression EXP isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atxn2 ataxin 2 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:40,264,601...40,335,637
Ensembl chr12:40,266,662...40,332,612
JBrowse link
G Atxn3 ataxin 3 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 affects expression ISO isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 decreases expression ISO isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions EXP [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Ctnnb1 catenin beta 1 affects expression ISO isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
EXP
ISO
[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA
isoquercitrin results in decreased activity of CYP1A1 protein
CTD PMID:16271822 PMID:20033131 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA] CTD PMID:20033131 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp51 cytochrome P450, family 51 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Egf epidermal growth factor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions EXP [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ibsp integrin-binding sialoprotein increases expression EXP isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jak2 Janus kinase 2 increases expression ISO isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Lct lactase multiple interactions EXP [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions EXP [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr14:77,380,264...77,402,007
Ensembl chr14:77,380,262...77,401,996
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Otx2 orthodenticle homeobox 2 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr15:25,500,037...25,511,619
Ensembl chr15:25,502,019...25,505,691
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha affects expression ISO isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sc5d sterol-C5-desaturase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions ISO isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr14:82,910,448...82,975,303
Ensembl chr14:82,909,981...82,975,263
JBrowse link
G Sqle squalene epoxidase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr19:37,214,461...37,221,099
Ensembl chr19:37,214,471...37,216,572
JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Tyk2 tyrosine kinase 2 affects expression ISO isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr 8:22,118,224...22,149,807
Ensembl chr 8:22,124,560...22,150,005
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
quercetin 3-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA CTD PMID:20033131 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Apoa1 apolipoprotein A1 increases secretion ISO isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Atf6 activating transcription factor 6 increases expression EXP isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atxn2 ataxin 2 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:40,264,601...40,335,637
Ensembl chr12:40,266,662...40,332,612
JBrowse link
G Atxn3 ataxin 3 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 affects expression ISO isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 decreases expression ISO isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions EXP [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Ctnnb1 catenin beta 1 affects expression ISO isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO
EXP
isoquercitrin results in decreased activity of CYP1A1 protein
[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA
CTD PMID:16271822 PMID:20033131 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA] CTD PMID:20033131 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp51 cytochrome P450, family 51 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Egf epidermal growth factor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions EXP [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ibsp integrin-binding sialoprotein increases expression EXP isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jak2 Janus kinase 2 increases expression ISO isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Lct lactase multiple interactions EXP [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions EXP [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr14:77,380,264...77,402,007
Ensembl chr14:77,380,262...77,401,996
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Otx2 orthodenticle homeobox 2 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr15:25,500,037...25,511,619
Ensembl chr15:25,502,019...25,505,691
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha affects expression ISO isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sc5d sterol-C5-desaturase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions ISO isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr14:82,910,448...82,975,303
Ensembl chr14:82,909,981...82,975,263
JBrowse link
G Sqle squalene epoxidase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr19:37,214,461...37,221,099
Ensembl chr19:37,214,471...37,216,572
JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Tyk2 tyrosine kinase 2 affects expression ISO isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr 8:22,118,224...22,149,807
Ensembl chr 8:22,124,560...22,150,005
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
quercetin 4'-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] CTD PMID:32602595 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]]; spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein] CTD PMID:32602595 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein] CTD PMID:32602595 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Cat catalase multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein] CTD PMID:32602595 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cryz crystallin zeta increases activity ISO spiraeoside results in increased activity of CRYZ protein CTD PMID:8968052 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein] CTD PMID:32602595 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Lct lactase multiple interactions EXP [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of spiraeoside CTD PMID:12663055 NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein] CTD PMID:32602595 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Plcg2 phospholipase C, gamma 2 decreases phosphorylation ISO spiraeoside results in decreased phosphorylation of PLCG2 protein CTD PMID:15613018 NCBI chr19:50,039,410...50,173,543
Ensembl chr19:50,045,020...50,173,220
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions EXP
ISO
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
spiraeoside inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]
CTD PMID:12663055 PMID:17495124 NCBI chr14:82,910,448...82,975,303
Ensembl chr14:82,909,981...82,975,263
JBrowse link
G Syk spleen associated tyrosine kinase decreases phosphorylation ISO spiraeoside results in decreased phosphorylation of SYK protein CTD PMID:15613018 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
quercitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO quercitrin results in decreased expression of ABCC4 mRNA CTD PMID:25193878 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 increases expression ISO quercitrin results in increased expression of ABCF2 mRNA CTD PMID:25193878 NCBI chr 4:7,122,850...7,135,607
Ensembl chr 4:7,122,890...7,135,669
JBrowse link
G Acbd6 acyl-CoA binding domain containing 6 decreases expression ISO quercitrin results in decreased expression of ACBD6 mRNA CTD PMID:25193878 NCBI chr13:73,196,504...73,334,077
Ensembl chr13:73,196,571...73,334,077
JBrowse link
G Acbd7 acyl-CoA binding domain containing 7 increases expression ISO quercitrin results in increased expression of ACBD7 mRNA CTD PMID:25193878 NCBI chr17:78,904,549...78,913,372
Ensembl chr17:78,904,873...78,910,671
JBrowse link
G Actn1 actinin, alpha 1 affects expression ISO quercitrin affects the expression of ACTN1 mRNA CTD PMID:25193878 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn4 actinin alpha 4 affects expression ISO quercitrin affects the expression of ACTN4 mRNA CTD PMID:25193878 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 decreases expression ISO quercitrin results in decreased expression of ADGRB1 mRNA CTD PMID:25193878 NCBI chr 7:115,766,484...115,828,514 JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO quercitrin results in decreased expression of ADGRF1 mRNA CTD PMID:25193878 NCBI chr 9:20,343,730...20,378,686 JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO quercitrin results in decreased expression of ADGRG1 mRNA CTD PMID:25193878 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 decreases expression ISO quercitrin results in decreased expression of ADGRG6 mRNA CTD PMID:25193878 NCBI chr 1:8,593,342...8,751,540
Ensembl chr 1:8,593,075...8,751,198
JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 increases expression ISO quercitrin results in increased expression of ADGRG7 mRNA CTD PMID:25193878 NCBI chr11:46,103,173...46,172,303
Ensembl chr11:46,793,777...46,856,291
Ensembl chr11:46,793,777...46,856,291
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 increases expression ISO quercitrin results in increased expression of ADGRV1 mRNA CTD PMID:25193878 NCBI chr 2:8,926,843...9,504,455
Ensembl chr 2:8,926,850...9,504,134
JBrowse link
G Adk adenosine kinase decreases expression ISO quercitrin results in decreased expression of ADK mRNA CTD PMID:25193878 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adra2c adrenoceptor alpha 2C increases expression ISO quercitrin results in increased expression of ADRA2C mRNA CTD PMID:25193878 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO quercitrin results in increased expression of AHNAK2 mRNA CTD PMID:25193878 NCBI chr 6:137,335,273...137,380,219 JBrowse link
G Alkbh7 alkB homolog 7 increases expression ISO quercitrin results in increased expression of ALKBH7 mRNA CTD PMID:25193878 NCBI chr 9:10,045,375...10,047,507
Ensembl chr 9:10,045,375...10,047,507
JBrowse link
G Anapc15 anaphase promoting complex subunit 15 decreases expression ISO quercitrin results in decreased expression of ANAPC15 mRNA CTD PMID:25193878 NCBI chr 1:166,981,738...166,985,363
Ensembl chr 1:166,983,175...166,985,054
JBrowse link
G Ar androgen receptor increases expression ISO quercitrin results in increased expression of AR mRNA CTD PMID:25193878 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 increases expression ISO quercitrin results in increased expression of ARAP2 mRNA CTD PMID:25193878 NCBI chr14:48,726,033...48,922,809
Ensembl chr14:48,726,045...48,922,983
JBrowse link
G Asb6 ankyrin repeat and SOCS box-containing 6 increases expression ISO quercitrin results in increased expression of ASB6 mRNA CTD PMID:25193878 NCBI chr 3:9,659,707...9,664,445
Ensembl chr 3:9,659,710...9,664,318
JBrowse link
G Atg7 autophagy related 7 decreases expression ISO quercitrin results in decreased expression of ATG7 mRNA CTD PMID:25193878 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 affects expression ISO quercitrin affects the expression of BAIAP2 mRNA CTD PMID:25193878 NCBI chr10:109,107,326...109,187,458
Ensembl chr10:109,107,389...109,187,115
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein] CTD PMID:23138875 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bdkrb1 bradykinin receptor B1 decreases expression ISO quercitrin results in decreased expression of BDKRB1 mRNA CTD PMID:25193878 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO quercitrin results in decreased expression of CAMK2B mRNA CTD PMID:25193878 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
quercitrin results in increased activity of CASP3 protein
quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]
CTD PMID:23138875 PMID:25193878 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases expression ISO quercitrin results in increased expression of CASP8 mRNA CTD PMID:25193878 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 decreases expression ISO quercitrin results in decreased expression of CCR9 mRNA CTD PMID:25193878 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130
JBrowse link
G Ccrl2 C-C motif chemokine receptor like 2 increases expression ISO quercitrin results in increased expression of CCRL2 mRNA CTD PMID:25193878 NCBI chr 8:119,324,298...119,326,954
Ensembl chr 8:119,324,613...119,326,938
JBrowse link
G Cd302 CD302 molecule decreases expression ISO quercitrin results in decreased expression of CD302 mRNA CTD PMID:25193878 NCBI chr 3:46,327,382...46,361,092
Ensembl chr 3:46,327,383...46,361,092
JBrowse link
G Cd38 CD38 molecule decreases expression ISO quercitrin results in decreased expression of CD38 mRNA CTD PMID:25193878 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd74 CD74 molecule affects expression ISO quercitrin affects the expression of CD74 mRNA CTD PMID:25193878 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO quercitrin results in decreased expression of CDH1 mRNA CTD PMID:25193878 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO quercitrin results in decreased expression of CDKN3 mRNA CTD PMID:25193878 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 increases expression ISO quercitrin results in increased expression of CELSR3 mRNA CTD PMID:25193878 NCBI chr 8:117,620,293...117,648,034
Ensembl chr 8:117,620,317...117,648,028
JBrowse link
G Cep95 centrosomal protein 95 increases expression ISO quercitrin results in increased expression of CEP95 mRNA CTD PMID:25193878 NCBI chr10:94,988,362...95,017,774
Ensembl chr10:94,988,362...95,016,344
JBrowse link
G Cers5 ceramide synthase 5 increases expression ISO quercitrin results in increased expression of CERS5 mRNA CTD PMID:25193878 NCBI chr 7:141,386,391...141,424,375
Ensembl chr 7:141,386,391...141,424,343
JBrowse link
G Cfap298 cilia and flagella associated protein 298 decreases expression ISO quercitrin results in decreased expression of CFAP298 mRNA CTD PMID:25193878 NCBI chr11:31,094,103...31,103,487
Ensembl chr11:31,094,084...31,103,520
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 decreases expression ISO quercitrin results in decreased expression of CHD2 mRNA CTD PMID:25193878 NCBI chr 1:134,757,934...134,873,053
Ensembl chr 1:134,757,934...134,871,167
JBrowse link
G Cldn10 claudin 10 affects expression ISO quercitrin affects the expression of CLDN10 mRNA CTD PMID:25193878 NCBI chr15:104,026,590...104,115,748
Ensembl chr15:104,026,601...104,115,748
JBrowse link
G Cldn23 claudin 23 affects expression ISO quercitrin affects the expression of CLDN23 mRNA CTD PMID:25193878 NCBI chr16:59,988,603...59,990,327
Ensembl chr16:59,988,603...59,990,326
JBrowse link
G Cldn4 claudin 4 affects expression ISO quercitrin affects the expression of CLDN4 mRNA CTD PMID:25193878 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cldn8 claudin 8 affects expression ISO quercitrin affects the expression of CLDN8 mRNA CTD PMID:25193878 NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO quercitrin results in decreased expression of COL3A1 mRNA CTD PMID:25193878 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO quercitrin results in decreased expression of COQ3 mRNA CTD PMID:25193878 NCBI chr 5:36,024,673...36,056,664
Ensembl chr 5:36,024,649...36,056,669
JBrowse link
G Crisp1 cysteine-rich secretory protein 1 decreases expression ISO quercitrin results in decreased expression of CRISP1 mRNA CTD PMID:25193878 NCBI chr 9:24,356,577...24,383,679
Ensembl chr 9:24,356,579...24,383,679
JBrowse link
G Cryzl1 crystallin zeta like 1 decreases expression ISO quercitrin results in decreased expression of CRYZL1 mRNA CTD PMID:25193878 NCBI chr11:31,847,741...31,893,042
Ensembl chr11:31,847,745...31,892,531
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 affects expression ISO quercitrin affects the expression of CSNK2A1 mRNA CTD PMID:25193878 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 affects expression ISO quercitrin affects the expression of CSNK2A2 mRNA CTD PMID:25193878 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043
JBrowse link
G Ctdspl2 CTD small phosphatase like 2 decreases expression ISO quercitrin results in decreased expression of CTDSPL2 mRNA CTD PMID:25193878 NCBI chr 3:113,906,803...113,957,289
Ensembl chr 3:113,918,629...113,960,101
JBrowse link
G Ctsb cathepsin B affects expression ISO quercitrin affects the expression of CTSB mRNA CTD PMID:25193878 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO quercitrin results in decreased activity of CYP1A1 protein CTD PMID:16271822 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO quercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression ISO quercitrin results in increased expression of CYP26B1 mRNA CTD PMID:25193878 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Dcun1d5 defective in cullin neddylation 1 domain containing 5 decreases expression ISO quercitrin results in decreased expression of DCUN1D5 mRNA CTD PMID:25193878 NCBI chr 8:5,437,071...5,458,152
Ensembl chr 8:5,437,071...5,458,152
JBrowse link
G Ddx19b DEAD-box helicase 19B decreases expression ISO quercitrin results in decreased expression of DDX19B mRNA CTD PMID:25193878 NCBI chr19:43,217,199...43,246,196
Ensembl chr19:43,217,161...43,275,287
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 decreases expression ISO quercitrin results in decreased expression of DELE1 mRNA CTD PMID:25193878 NCBI chr18:31,396,897...31,409,914
Ensembl chr18:31,396,922...31,409,907
JBrowse link
G Dgkq diacylglycerol kinase, theta affects expression ISO quercitrin affects the expression of DGKQ mRNA CTD PMID:25193878 NCBI chr14:2,069,409...2,083,370
Ensembl chr14:2,069,409...2,083,370
JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases activity ISO quercitrin results in decreased activity of DHRS11 protein CTD PMID:30926317 NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
JBrowse link
G Dtwd1 DTW domain containing 1 decreases expression ISO quercitrin results in decreased expression of DTWD1 mRNA CTD PMID:25193878 NCBI chr 3:118,427,790...118,443,003
Ensembl chr 3:118,430,511...118,442,098
JBrowse link
G Egr2 early growth response 2 increases expression ISO quercitrin results in increased expression of EGR2 mRNA CTD PMID:25193878 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO quercitrin results in increased expression of EPAS1 mRNA CTD PMID:25193878 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO quercitrin results in decreased expression of ERCC1 mRNA CTD PMID:25193878 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO quercitrin results in decreased expression of ERCC2 mRNA CTD PMID:25193878 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 increases expression ISO quercitrin results in increased expression of ERI2 mRNA CTD PMID:25193878 NCBI chr 1:189,540,145...189,549,891
Ensembl chr 1:189,540,145...189,549,891
JBrowse link
G Eva1a eva-1 homolog A, regulator of programmed cell death decreases expression ISO quercitrin results in decreased expression of EVA1A mRNA CTD PMID:25193878 NCBI chr 4:112,714,023...112,823,659
Ensembl chr 4:112,773,938...112,823,659
JBrowse link
G F11r F11 receptor affects expression ISO quercitrin affects the expression of F11R mRNA CTD PMID:25193878 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression ISO quercitrin results in increased expression of F2RL1 mRNA CTD PMID:25193878 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 decreases expression ISO quercitrin results in decreased expression of F2RL2 mRNA CTD PMID:25193878 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO quercitrin results in increased expression of F3 mRNA CTD PMID:25193878 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Faim Fas apoptotic inhibitory molecule increases expression ISO quercitrin results in increased expression of FAIM mRNA CTD PMID:25193878 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Fam102a family with sequence similarity 102, member A increases expression ISO quercitrin results in increased expression of FAM102A mRNA CTD PMID:25193878 NCBI chr 3:11,554,084...11,586,315
Ensembl chr 3:11,554,457...11,586,303
JBrowse link
G Fam216a family with sequence similarity 216, member A decreases expression ISO quercitrin results in decreased expression of FAM216A mRNA CTD PMID:25193878 NCBI chr12:39,679,688...39,688,831
Ensembl chr12:39,679,688...39,688,823
JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C increases expression ISO quercitrin results in increased expression of FAM3C mRNA CTD PMID:25193878 NCBI chr 4:49,388,962...49,439,892
Ensembl chr 4:49,387,989...49,439,867
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO quercitrin results in increased expression of FAM43A mRNA CTD PMID:25193878 NCBI chr11:73,676,601...73,679,003
Ensembl chr11:73,676,601...73,678,984
JBrowse link
G Fam50a family with sequence similarity 50, member A increases expression ISO quercitrin results in increased expression of FAM50A mRNA CTD PMID:25193878 NCBI chr  X:156,392,646...156,399,763
Ensembl chr  X:156,392,630...156,399,760
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO quercitrin results in increased expression of FAS mRNA CTD PMID:25193878 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fdcsp follicular dendritic cell secreted protein decreases expression ISO quercitrin results in decreased expression of FDCSP mRNA CTD PMID:25193878 NCBI chr14:21,818,999...21,823,687
Ensembl chr14:21,819,395...21,823,687
JBrowse link
G Flg filaggrin increases expression ISO quercitrin results in increased expression of FLG mRNA CTD PMID:25193878 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO quercitrin results in increased expression of FZD4 mRNA CTD PMID:25193878 NCBI chr 1:153,589,471...153,598,376
Ensembl chr 1:153,589,471...153,598,375
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 increases expression ISO quercitrin results in increased expression of GABBR2 mRNA CTD PMID:25193878 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO quercitrin affects the expression of GADD45 mRNA CTD PMID:25193878 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Galk2 galactokinase 2 increases expression ISO quercitrin results in increased expression of GALK2 mRNA CTD PMID:25193878 NCBI chr 3:118,137,097...118,268,838
Ensembl chr 3:118,136,838...118,268,836
JBrowse link
G Galr3 galanin receptor 3 increases expression ISO quercitrin results in increased expression of GALR3 mRNA CTD PMID:25193878 NCBI chr 7:120,271,451...120,276,243
Ensembl chr 7:120,273,117...120,275,581
JBrowse link
G Gimap6 GTPase, IMAP family member 6 increases expression ISO quercitrin results in increased expression of GIMAP6 mRNA CTD PMID:25193878 NCBI chr 4:78,337,528...78,342,937
Ensembl chr 4:78,336,423...78,342,863
JBrowse link
G Glipr1 GLI pathogenesis-related 1 decreases expression ISO quercitrin results in decreased expression of GLIPR1 mRNA CTD PMID:25193878 NCBI chr 7:54,767,828...54,778,823
Ensembl chr 7:54,767,827...54,778,848
JBrowse link
G Golim4 golgi integral membrane protein 4 increases expression ISO quercitrin results in increased expression of GOLIM4 mRNA CTD PMID:25193878 NCBI chr 2:174,321,303...174,413,847
Ensembl chr 2:174,322,673...174,413,236
JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO quercitrin results in increased expression of GPR137B mRNA CTD PMID:25193878 NCBI chr17:90,670,852...90,709,003
Ensembl chr17:90,670,872...90,746,804
JBrowse link
G Gpr173 G-protein coupled receptor 173 increases expression ISO quercitrin results in increased expression of GPR173 mRNA CTD PMID:25193878 NCBI chr  X:22,417,753...22,418,873
Ensembl chr  X:22,417,753...22,418,873
JBrowse link
G Gpr174 G protein-coupled receptor 174 increases expression ISO quercitrin results in increased expression of GPR174 mRNA CTD PMID:25193878 NCBI chr  X:78,358,347...78,399,944
Ensembl chr  X:78,372,257...78,399,944
JBrowse link
G Gpr19 G protein-coupled receptor 19 increases expression ISO quercitrin results in increased expression of GPR19 mRNA CTD PMID:25193878 NCBI chr 4:168,639,930...168,668,345
Ensembl chr 4:168,639,940...168,656,673
JBrowse link
G Gpr4 G protein-coupled receptor 4 increases expression ISO quercitrin results in increased expression of GPR4 mRNA CTD PMID:25193878 NCBI chr 1:80,125,639...80,136,786
Ensembl chr 1:80,135,391...80,136,880
JBrowse link
G Gpr63 G protein-coupled receptor 63 increases expression ISO quercitrin results in increased expression of GPR63 mRNA CTD PMID:25193878 NCBI chr 5:39,258,438...39,374,187
Ensembl chr 5:39,329,423...39,370,900
JBrowse link
G Gpr83 G protein-coupled receptor 83 increases expression ISO quercitrin results in increased expression of GPR83 mRNA CTD PMID:25193878 NCBI chr 8:13,365,583...13,376,071
Ensembl chr 8:13,365,583...13,376,070
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression ISO quercitrin results in decreased expression of GSTP1 mRNA CTD PMID:25193878 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 increases expression ISO quercitrin results in increased expression of HAVCR2 mRNA CTD PMID:25193878 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO quercitrin results in increased expression of HGF mRNA CTD PMID:25193878 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO quercitrin results in increased expression of HMGA2 mRNA CTD PMID:25193878 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO quercitrin results in decreased expression of HMGB2 mRNA CTD PMID:25193878 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO quercitrin results in decreased expression of HNF4A mRNA CTD PMID:25193878 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 affects expression ISO quercitrin affects the expression of HSP90AA1 mRNA CTD PMID:25193878 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like affects expression ISO quercitrin affects the expression of HSPA1L mRNA CTD PMID:25193878 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects expression ISO quercitrin affects the expression of HSPA8 mRNA CTD PMID:25193878 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Ifng interferon gamma multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects expression ISO quercitrin affects the expression of IGF1R mRNA CTD PMID:25193878 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il15 interleukin 15 decreases expression ISO quercitrin results in decreased expression of IL15 mRNA CTD PMID:25193878 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Ino80c INO80 complex subunit C decreases expression ISO quercitrin results in decreased expression of INO80C mRNA CTD PMID:25193878 NCBI chr18:15,995,005...16,009,639
Ensembl chr18:15,995,000...16,009,710
JBrowse link
G Inpp4a inositol polyphosphate-4-phosphatase type I A affects expression ISO quercitrin affects the expression of INPP4A mRNA CTD PMID:25193878 NCBI chr 9:43,889,887...44,006,593
Ensembl chr 9:43,889,473...44,004,325
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D affects expression ISO quercitrin affects the expression of INPP5D mRNA CTD PMID:25193878 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771
JBrowse link
G Insr insulin receptor affects expression ISO quercitrin affects the expression of INSR mRNA CTD PMID:25193878 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 increases expression ISO quercitrin results in increased expression of IRF2BP2 mRNA CTD PMID:25193878 NCBI chr19:59,497,021...59,502,298
Ensembl chr19:59,499,876...59,502,161
JBrowse link
G Itgb1 integrin subunit beta 1 affects expression ISO quercitrin affects the expression of ITGB1 mRNA CTD PMID:25193878 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Jaml junction adhesion molecule like increases expression ISO quercitrin results in increased expression of JAML mRNA CTD PMID:25193878 NCBI chr 8:49,378,644...49,408,894
Ensembl chr 8:49,378,644...49,410,088
JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 increases expression ISO quercitrin results in increased expression of JPT2 mRNA CTD PMID:25193878 NCBI chr10:14,304,108...14,324,170
Ensembl chr10:14,304,104...14,324,211
JBrowse link
G Kat5 lysine acetyltransferase 5 affects expression ISO quercitrin affects the expression of TIP60 mRNA CTD PMID:25193878 NCBI chr 1:220,967,795...220,974,596
Ensembl chr 1:220,967,796...220,974,597
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO quercitrin results in increased expression of KDM3A mRNA CTD PMID:25193878 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kdr kinase insert domain receptor increases expression ISO quercitrin results in increased expression of KDR mRNA CTD PMID:25193878 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO quercitrin results in increased expression of KEAP1 mRNA CTD PMID:25193878 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Klhl28 kelch-like family member 28 increases expression ISO quercitrin results in increased expression of KLHL28 mRNA CTD PMID:25193878 NCBI chr 6:86,680,826...86,713,370
Ensembl chr 6:86,684,413...86,713,370
JBrowse link
G Krt81 keratin 81 decreases expression ISO quercitrin results in decreased expression of KRT81 mRNA CTD PMID:25193878 NCBI chr 7:143,107,901...143,113,006
Ensembl chr 7:143,107,901...143,112,960
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 affects expression ISO quercitrin affects the expression of LEF1 mRNA CTD PMID:25193878 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like affects expression ISO quercitrin affects the expression of HLA-A mRNA CTD PMID:25193878 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G LOC100911237 zinc finger protein 420-like increases expression ISO quercitrin results in increased expression of ZNF502 mRNA CTD PMID:25193878 NCBI chr 1:31,494,043...31,519,034 JBrowse link
G LOC102552569 P2Y purinoceptor 11-like increases expression ISO quercitrin results in increased expression of P2RY11 mRNA CTD PMID:25193878 NCBI chr 8:21,910,636...21,911,499 JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) affects expression ISO quercitrin affects the expression of HSPA6 mRNA CTD PMID:25193878 NCBI chr13:89,408,703...89,411,500 JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 increases expression ISO quercitrin results in increased expression of LPAR3 mRNA CTD PMID:25193878 NCBI chr 2:252,090,634...252,159,221
Ensembl chr 2:252,090,669...252,159,903
JBrowse link
G Lpar5 lysophosphatidic acid receptor 5 increases expression ISO quercitrin results in increased expression of LPAR5 mRNA CTD PMID:25193878 NCBI chr 4:157,581,000...157,596,454
Ensembl chr 4:157,594,436...157,595,972
JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 decreases expression ISO quercitrin results in decreased expression of LPAR6 mRNA CTD PMID:25193878 NCBI chr15:55,126,953...55,128,762
Ensembl chr15:55,126,953...55,128,761
JBrowse link
G Mat2a methionine adenosyltransferase 2A increases expression ISO quercitrin results in increased expression of MAT2A mRNA CTD PMID:25193878 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mc1r melanocortin 1 receptor increases expression ISO quercitrin results in increased expression of MC1R mRNA CTD PMID:25193878 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression ISO quercitrin results in decreased expression of MCTS1 mRNA CTD PMID:25193878 NCBI chr  X:124,894,269...124,906,129
Ensembl chr  X:124,894,466...124,906,162
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression ISO quercitrin results in decreased expression of MRPL12 mRNA CTD PMID:25193878 NCBI chr10:109,658,032...109,662,535
Ensembl chr10:109,658,032...109,662,535
JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 decreases expression ISO quercitrin results in decreased expression of MRPL22 mRNA CTD PMID:25193878 NCBI chr10:43,601,786...43,612,119
Ensembl chr10:43,601,689...43,612,121
JBrowse link
G Msn moesin affects expression ISO quercitrin affects the expression of MSN mRNA CTD PMID:25193878 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Myl2 myosin light chain 2 affects expression ISO quercitrin affects the expression of MYL2 mRNA CTD PMID:25193878 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Myl9 myosin light chain 9 affects expression ISO quercitrin affects the expression of MYL9 mRNA CTD PMID:25193878 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Myom2 myomesin 2 increases expression ISO quercitrin results in increased expression of MYOM2 mRNA CTD PMID:25193878 NCBI chr16:79,587,136...79,672,871
Ensembl chr16:79,587,640...79,671,719
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit decreases expression ISO quercitrin results in decreased expression of LSMD1 mRNA CTD PMID:25193878 NCBI chr10:55,997,614...55,998,691
Ensembl chr10:55,997,614...55,998,691
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein] CTD PMID:23138875 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein increases expression ISO quercitrin results in increased expression of NFRKB mRNA CTD PMID:25193878 NCBI chr 8:32,530,412...32,561,955
Ensembl chr 8:32,530,412...32,561,955
JBrowse link
G Nmur1 neuromedin U receptor 1 decreases expression ISO quercitrin results in decreased expression of NMUR1 mRNA CTD PMID:25193878 NCBI chr 9:93,402,871...93,407,264
Ensembl chr 9:93,403,314...93,404,883
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npbwr1 neuropeptides B and W receptor 1 increases expression ISO quercitrin results in increased expression of NPBWR1 mRNA CTD PMID:25193878 NCBI chr 5:13,379,772...13,380,761
Ensembl chr 5:13,379,772...13,380,761
JBrowse link
G Npffr2 neuropeptide FF receptor 2 decreases expression ISO quercitrin results in decreased expression of NPFFR2 mRNA CTD PMID:25193878 NCBI chr14:20,148,485...20,193,577
Ensembl chr14:20,148,913...20,193,083
JBrowse link
G Npy5r neuropeptide Y receptor Y5 increases expression ISO quercitrin results in increased expression of NPY5R mRNA CTD PMID:25193878 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Nuak2 NUAK family kinase 2 decreases expression ISO quercitrin results in decreased expression of NUAK2 mRNA CTD PMID:25193878 NCBI chr13:49,092,306...49,109,055
Ensembl chr13:49,092,306...49,109,050
JBrowse link
G Ocln occludin affects expression ISO quercitrin affects the expression of OCLN mRNA CTD PMID:25193878 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO quercitrin results in increased expression of ODC1 mRNA CTD PMID:25193878 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Oga O-GlcNAcase increases expression ISO quercitrin results in increased expression of OGA mRNA CTD PMID:25193878 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
G Ogfod2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 increases expression ISO quercitrin results in increased expression of OGFOD2 mRNA CTD PMID:25193878 NCBI chr12:37,907,130...37,910,446
Ensembl chr12:37,907,130...37,910,439
JBrowse link
G Oma1 OMA1 zinc metallopeptidase increases expression ISO quercitrin results in increased expression of OMA1 mRNA CTD PMID:25193878 NCBI chr 5:122,847,624...122,900,475
Ensembl chr 5:122,847,645...122,900,475
JBrowse link
G P2rx2 purinergic receptor P2X 2 increases expression ISO quercitrin results in increased expression of P2RX2 mRNA CTD PMID:25193878 NCBI chr12:52,397,666...52,401,005
Ensembl chr12:52,397,792...52,401,015
JBrowse link
G P2rx3 purinergic receptor P2X 3 increases expression ISO quercitrin results in increased expression of P2RX3 mRNA CTD PMID:25193878 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 decreases expression ISO quercitrin results in decreased expression of P2RY6 mRNA CTD PMID:25193878 NCBI chr 1:165,972,439...166,008,348
Ensembl chr 1:165,972,440...165,997,751
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein] CTD PMID:23138875 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Patz1 POZ (BTB) and AT hook containing zinc finger 1 decreases expression ISO quercitrin results in decreased expression of PATZ1 mRNA CTD PMID:25193878 NCBI chr14:83,509,763...83,528,898
Ensembl chr14:83,510,278...83,528,898
JBrowse link
G Pex16 peroxisomal biogenesis factor 16 decreases expression ISO quercitrin results in decreased expression of PEX16 mRNA CTD PMID:25193878 NCBI chr 3:81,283,137...81,292,575
Ensembl chr 3:81,283,137...81,292,573
JBrowse link
G Pidd1 p53-induced death domain protein 1 increases expression ISO quercitrin results in increased expression of PIDD1 mRNA CTD PMID:25193878 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha affects expression ISO quercitrin affects the expression of PIK3C2A mRNA CTD PMID:25193878 NCBI chr 1:185,210,922...185,326,314
Ensembl chr 1:185,210,922...185,326,314
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 affects expression ISO quercitrin affects the expression of PIK3R1 mRNA CTD PMID:25193878 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Plcb2 phospholipase C, beta 2 affects expression ISO quercitrin affects the expression of PLCB2 mRNA CTD PMID:25193878 NCBI chr 3:110,497,760...110,517,563
Ensembl chr 3:110,498,114...110,517,163
JBrowse link
G Plce1 phospholipase C, epsilon 1 affects expression ISO quercitrin affects the expression of PLCE1 mRNA CTD PMID:25193878 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064
JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine decreases expression ISO quercitrin results in decreased expression of PLGRKT mRNA CTD PMID:25193878 NCBI chr 1:247,502,274...247,514,540
Ensembl chr 1:247,502,280...247,514,540
JBrowse link
G Poc1a POC1 centriolar protein A decreases expression ISO quercitrin results in decreased expression of POC1A mRNA CTD PMID:25193878 NCBI chr 8:114,982,764...115,050,844
Ensembl chr 8:114,986,326...115,050,728
JBrowse link
G Polh DNA polymerase eta increases expression ISO quercitrin results in increased expression of POLH mRNA CTD PMID:25193878 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Polrmt RNA polymerase mitochondrial decreases expression ISO quercitrin results in decreased expression of POLRMT mRNA CTD PMID:25193878 NCBI chr 7:12,840,907...12,851,153
Ensembl chr 7:12,840,938...12,851,153
JBrowse link
G Pomt2 protein-O-mannosyltransferase 2 increases expression ISO quercitrin results in increased expression of POMT2 mRNA CTD PMID:25193878 NCBI chr 6:111,137,329...111,176,991
Ensembl chr 6:111,135,349...111,176,918
JBrowse link
G Pou5f2 POU domain class 5, transcription factor 2 decreases expression ISO quercitrin results in decreased expression of POU5F2 mRNA CTD PMID:25193878 NCBI chr 2:5,437,067...5,438,301
Ensembl chr 2:5,437,067...5,438,301
JBrowse link
G Prkcb protein kinase C, beta affects expression ISO quercitrin affects the expression of PRKCB mRNA CTD PMID:25193878 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prr3 proline rich 3 decreases expression ISO quercitrin results in decreased expression of PRR3 mRNA CTD PMID:25193878 NCBI chr20:3,300,247...3,307,262
Ensembl chr20:3,299,730...3,307,673
JBrowse link
G Psd4 pleckstrin and Sec7 domain containing 4 increases expression ISO quercitrin results in increased expression of PSD4 mRNA CTD PMID:25193878 NCBI chr 3:1,478,432...1,515,094
Ensembl chr 3:1,478,525...1,514,934
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 decreases expression ISO quercitrin results in decreased expression of PSMA6 mRNA CTD PMID:25193878 NCBI chr 6:76,174,460...76,205,429
Ensembl chr 6:76,174,452...76,205,426
JBrowse link
G Psma8 proteasome 20S subunit alpha 8 decreases expression ISO quercitrin results in decreased expression of PSMA8 mRNA CTD PMID:25193878 NCBI chr18:6,114,757...6,182,393
Ensembl chr18:6,114,701...6,182,535
JBrowse link
G Psmb6 proteasome 20S subunit beta 6 decreases expression ISO quercitrin results in decreased expression of PSMB6 mRNA CTD PMID:25193878 NCBI chr10:57,131,339...57,133,685
Ensembl chr10:57,131,386...57,133,637
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression ISO quercitrin results in decreased expression of PSMB9 mRNA CTD PMID:25193878 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 increases expression ISO quercitrin results in increased expression of PTGDR2 mRNA CTD PMID:25193878 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta affects expression ISO quercitrin affects the expression of PTK2B mRNA CTD PMID:25193878 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Ptpru protein tyrosine phosphatase, receptor type, U decreases expression ISO quercitrin results in decreased expression of PTPRU mRNA CTD PMID:25193878 NCBI chr 5:149,922,374...149,996,352
Ensembl chr 5:149,922,352...149,996,334
JBrowse link
G Rac3 Rac family small GTPase 3 affects expression ISO quercitrin affects the expression of RAC3 mRNA CTD PMID:25193878 NCBI chr10:109,903,920...109,906,596
Ensembl chr10:109,904,259...109,906,232
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family affects expression ISO quercitrin affects the expression of RAP1A mRNA CTD PMID:25193878 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rbak RB-associated KRAB zinc finger increases expression ISO quercitrin results in increased expression of RBAK mRNA CTD PMID:25193878 NCBI chr12:13,428,648...13,442,279
Ensembl chr12:13,428,685...13,442,286
JBrowse link
G Rbks ribokinase decreases expression ISO quercitrin results in decreased expression of RBKS mRNA CTD PMID:25193878 NCBI chr 6:26,051,568...26,128,762
Ensembl chr 6:26,051,396...26,128,906
JBrowse link
G Rbm15b RNA binding motif protein 15B increases expression ISO quercitrin results in increased expression of RBM15B mRNA CTD PMID:25193878 NCBI chr 8:115,618,242...115,623,068
Ensembl chr 8:115,618,555...115,621,394
JBrowse link
G Rbm38 RNA binding motif protein 38 increases expression ISO quercitrin results in increased expression of RBM38 mRNA CTD PMID:25193878 NCBI chr 3:171,037,891...171,050,500
Ensembl chr 3:171,037,957...171,050,475
JBrowse link
G Rbm39 RNA binding motif protein 39 increases expression ISO quercitrin results in increased expression of RBM39 mRNA CTD PMID:25193878 NCBI chr 3:151,691,498...151,724,723
Ensembl chr 3:151,691,514...151,724,654
JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 decreases expression ISO quercitrin results in decreased expression of RCHY1 mRNA CTD PMID:25193878 NCBI chr14:17,615,968...17,631,715
Ensembl chr14:17,615,968...17,631,714
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein] CTD PMID:23138875 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1310553 similar to expressed sequence AI597479 decreases expression ISO quercitrin results in decreased expression of C2ORF49 mRNA CTD PMID:25193878 NCBI chr 9:49,903,085...49,913,754
Ensembl chr 9:49,903,085...49,913,744
JBrowse link
G Riok1 RIO kinase 1 increases expression ISO quercitrin results in increased expression of RIOK1 mRNA CTD PMID:25193878 NCBI chr17:27,429,421...27,452,353
Ensembl chr17:27,429,416...27,452,314
JBrowse link
G Rnf14 ring finger protein 14 decreases expression ISO quercitrin results in decreased expression of RNF14 mRNA CTD PMID:25193878 NCBI chr18:31,443,424...31,468,641
Ensembl chr18:31,444,472...31,468,640
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 affects expression ISO quercitrin affects the expression of ROCK1 mRNA CTD PMID:25193878 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G RT1-Ba RT1 class II, locus Ba affects expression ISO quercitrin affects the expression of HLA-DQA1 mRNA CTD PMID:25193878 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression ISO quercitrin affects the expression of HLA-E mRNA CTD PMID:25193878 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Sap18 Sin3A associated protein 18 increases expression ISO quercitrin results in increased expression of SAP18 mRNA CTD PMID:25193878 NCBI chr15:38,069,320...38,073,625
Ensembl chr15:38,069,320...38,073,622
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 decreases expression ISO quercitrin results in decreased expression of SAT1 mRNA CTD PMID:25193878 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO quercitrin results in increased expression of SERTAD1 mRNA CTD PMID:25193878 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 decreases expression ISO quercitrin results in decreased expression of SF3B1 mRNA CTD PMID:25193878 NCBI chr 9:61,594,620...61,634,510
Ensembl chr 9:61,594,620...61,634,510
JBrowse link
G Slc16a13 solute carrier family 16, member 13 decreases expression ISO quercitrin results in decreased expression of SLC16A13 mRNA CTD PMID:25193878 NCBI chr10:56,827,591...56,831,324
Ensembl chr10:56,827,594...56,831,243
JBrowse link
G Slc16a4 solute carrier family 16, member 4 decreases expression ISO quercitrin results in decreased expression of SLC16A4 mRNA CTD PMID:25193878 NCBI chr 2:210,045,122...210,161,017
Ensembl chr 2:210,045,161...210,068,502
JBrowse link
G Slc22a18 solute carrier family 22, member 18 decreases expression ISO quercitrin results in decreased expression of SLC22A18 mRNA CTD PMID:25193878 NCBI chr 1:216,676,330...216,700,632
Ensembl chr 1:216,677,373...216,700,641
JBrowse link
G Slc25a40 solute carrier family 25, member 40 decreases expression ISO quercitrin results in decreased expression of SLC25A40 mRNA CTD PMID:25193878 NCBI chr 4:22,619,700...22,661,685
Ensembl chr 4:22,576,576...22,661,722
JBrowse link
G Slc39a8 solute carrier family 39 member 8 decreases expression ISO quercitrin results in decreased expression of SLC39A8 mRNA CTD PMID:25193878 NCBI chr 2:241,028,851...241,092,584
Ensembl chr 2:241,029,693...241,092,582
JBrowse link
G Slc7a9 solute carrier family 7 member 9 increases expression ISO quercitrin results in increased expression of SLC7A9 mRNA CTD PMID:25193878 NCBI chr 1:91,709,034...91,738,492
Ensembl chr 1:91,716,383...91,738,494
JBrowse link
G Slfnl1 schlafen-like 1 increases expression ISO quercitrin results in increased expression of SLFNL1 mRNA CTD PMID:25193878 NCBI chr 5:139,467,933...139,473,599
Ensembl chr 5:139,468,546...139,473,017
JBrowse link
G Smad3 SMAD family member 3 increases expression ISO quercitrin results in increased expression of SMAD3 mRNA CTD PMID:25193878 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 increases expression ISO quercitrin results in increased expression of SMPD1 mRNA CTD PMID:25193878 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Snai2 snail family transcriptional repressor 2 affects expression ISO quercitrin affects the expression of SNAI2 mRNA CTD PMID:25193878 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 affects expression ISO quercitrin affects the expression of SORBS1 mRNA CTD PMID:25193878 NCBI chr 1:259,373,921...259,502,108
Ensembl chr 1:259,376,933...259,484,569
JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression ISO quercitrin results in decreased expression of SORL1 mRNA CTD PMID:25193878 NCBI chr 8:46,228,077...46,287,171 JBrowse link
G Sp4 Sp4 transcription factor increases expression ISO quercitrin results in increased expression of SP4 mRNA CTD PMID:25193878 NCBI chr 6:146,135,877...146,201,344
Ensembl chr 6:146,135,877...146,195,819
JBrowse link
G Spata18 spermatogenesis associated 18 increases expression ISO quercitrin results in increased expression of SPATA18 mRNA CTD PMID:25193878 NCBI chr14:37,081,529...37,108,245
Ensembl chr14:37,081,427...37,108,341
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects expression ISO quercitrin affects the expression of SRC mRNA CTD PMID:25193878 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 increases expression ISO quercitrin results in increased expression of SRD5A3 mRNA CTD PMID:25193878 NCBI chr14:34,554,769...34,570,423
Ensembl chr14:34,556,220...34,570,356
JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 increases expression ISO quercitrin results in increased expression of SRRM2 mRNA CTD PMID:25193878 NCBI chr10:13,128,820...13,162,956
Ensembl chr10:13,145,099...13,162,343
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase increases expression ISO quercitrin results in increased expression of SUGCT mRNA CTD PMID:25193878 NCBI chr17:49,991,314...51,030,950 JBrowse link
G Sugp1 SURP and G patch domain containing 1 increases expression ISO quercitrin results in increased expression of SUGP1 mRNA CTD PMID:25193878 NCBI chr16:21,100,923...21,131,795
Ensembl chr16:21,100,924...21,131,795
JBrowse link
G Tcea1 transcription elongation factor A1 decreases expression ISO quercitrin results in decreased expression of TCEA1 mRNA CTD PMID:25193878 NCBI chr 5:14,511,183...14,548,494
Ensembl chr 5:14,511,183...14,548,429
JBrowse link
G Tcea2 transcription elongation factor A2 decreases expression ISO quercitrin results in decreased expression of TCEA2 mRNA CTD PMID:25193878 NCBI chr 3:177,187,686...177,195,898
Ensembl chr 3:177,188,044...177,195,894
JBrowse link
G Tcf7 transcription factor 7 affects expression ISO quercitrin affects the expression of TCF7 mRNA CTD PMID:25193878 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link
G Tfb1m transcription factor B1, mitochondrial decreases expression ISO quercitrin results in decreased expression of TFB1M mRNA CTD PMID:25193878 NCBI chr 1:44,433,116...44,474,674
Ensembl chr 1:44,433,116...44,474,674
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 decreases expression ISO quercitrin results in decreased expression of TGIF2 mRNA CTD PMID:25193878 NCBI chr 3:152,906,961...152,924,380
Ensembl chr 3:152,909,189...152,924,377
JBrowse link
G Tgm2 transglutaminase 2 decreases expression ISO quercitrin results in decreased expression of TGM2 mRNA CTD PMID:25193878 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thsd1 thrombospondin type 1 domain containing 1 increases expression ISO quercitrin results in increased expression of THSD1 mRNA CTD PMID:25193878 NCBI chr16:74,680,621...74,712,368
Ensembl chr16:74,680,621...74,710,704
JBrowse link
G Tmem160 transmembrane protein 160 decreases expression ISO quercitrin results in decreased expression of TMEM160 mRNA CTD PMID:25193878 NCBI chr 1:78,417,719...78,420,427
Ensembl chr 1:78,417,719...78,420,427
JBrowse link
G Tmem208 transmembrane protein 208 decreases expression ISO quercitrin results in decreased expression of TMEM208 mRNA CTD PMID:25193878 NCBI chr19:37,282,018...37,284,718
Ensembl chr19:37,282,018...37,284,718
JBrowse link
G Tmem242 transmembrane protein 242 increases expression ISO quercitrin results in increased expression of TMEM242 mRNA CTD PMID:25193878 NCBI chr 1:46,302,546...46,329,885
Ensembl chr 1:46,302,970...46,329,682
JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 decreases expression ISO quercitrin results in decreased expression of TMX1 mRNA CTD PMID:25193878 NCBI chr 6:92,864,123...92,875,141
Ensembl chr 6:92,864,123...92,874,204
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO quercitrin results in decreased expression of TNFRSF1A mRNA CTD PMID:25193878 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B decreases expression ISO quercitrin results in decreased expression of TNFRSF1B mRNA CTD PMID:25193878 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tp63 tumor protein p63 decreases expression ISO quercitrin results in decreased expression of TP63 mRNA CTD PMID:25193878 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tspan14 tetraspanin 14 decreases expression ISO quercitrin results in decreased expression of TSPAN14 mRNA CTD PMID:25193878 NCBI chr16:17,538,855...17,595,960
Ensembl chr16:17,538,855...17,595,960
JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 increases expression ISO quercitrin results in increased expression of U2AF2 mRNA CTD PMID:25193878 NCBI chr 1:72,312,260...72,329,828
Ensembl chr 1:72,312,727...72,329,856
JBrowse link
G Uts2r urotensin 2 receptor increases expression ISO quercitrin results in increased expression of UTS2R mRNA CTD PMID:25193878 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
G Vom1r51 vomeronasal 1 receptor 51 increases expression ISO quercitrin results in increased expression of VN1R1 mRNA CTD PMID:25193878 NCBI chr 1:66,872,787...66,873,740
Ensembl chr 1:66,872,787...66,873,740
JBrowse link
G Vwa8 von Willebrand factor A domain containing 8 decreases expression ISO quercitrin results in decreased expression of VWA8 mRNA CTD PMID:25193878 NCBI chr15:61,069,439...61,153,292
NCBI chr15:61,158,510...61,467,462
Ensembl chr15:61,069,581...61,152,506
JBrowse link
G Was WASP actin nucleation promoting factor affects expression ISO quercitrin affects the expression of WAS mRNA CTD PMID:25193878 NCBI chr  X:15,155,246...15,164,099
Ensembl chr  X:15,155,230...15,164,105
JBrowse link
G Wdr33 WD repeat domain 33 decreases expression ISO quercitrin results in decreased expression of WDR33 mRNA CTD PMID:25193878 NCBI chr18:24,584,832...24,689,681
Ensembl chr18:24,584,900...24,689,636
JBrowse link
G Wwox WW domain-containing oxidoreductase decreases expression ISO quercitrin results in decreased expression of WWOX mRNA CTD PMID:25193878 NCBI chr19:46,761,353...47,695,247 JBrowse link
G Zan zonadhesin increases expression ISO quercitrin results in increased expression of ZAN mRNA CTD PMID:25193878 NCBI chr12:22,285,377...22,389,008 JBrowse link
G Zcchc14 zinc finger CCHC-type containing 14 increases expression ISO quercitrin results in increased expression of ZCCHC14 mRNA CTD PMID:25193878 NCBI chr19:53,644,500...53,688,624
Ensembl chr19:53,647,815...53,688,597
JBrowse link
rutin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ABCA1 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ABCA1 protein] CTD PMID:25478064 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Acly ATP citrate lyase decreases activity ISO Rutin results in decreased activity of ACLY protein CTD PMID:17032037 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO Rutin inhibits the reaction [Glucose results in increased expression of AGER mRNA] CTD PMID:19557821 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen multiple interactions EXP Rutin inhibits the reaction [Isoproterenol results in increased expression of AGT protein] CTD PMID:24117263 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahr aryl hydrocarbon receptor decreases localization
multiple interactions
ISO Rutin results in decreased localization of AHR protein
Rutin promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased localization of AHR protein]
CTD PMID:21756928 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Rutin inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein] CTD PMID:22426011 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases localization ISO Rutin results in increased localization of ARNT protein CTD PMID:21756928 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Atxn2 ataxin 2 multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:40,264,601...40,335,637
Ensembl chr12:40,266,662...40,332,612
JBrowse link
G Atxn3 ataxin 3 multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression
multiple interactions
increases expression
ISO Rutin affects the expression of BAX protein
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]
Rutin results in increased expression of BAX protein
CTD PMID:15975156 PMID:28811126 PMID:29522708 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions EXP Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of BBC3 mRNA] CTD PMID:27239252 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression
multiple interactions
decreases expression
ISO
EXP
Rutin affects the expression of BCL2 protein
Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]
Rutin results in decreased expression of BCL2 protein
Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 mRNA]
Rutin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]
CTD PMID:15975156 PMID:19557821 PMID:26062544 PMID:28811126 PMID:29522708 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of BCL2L1 mRNA] CTD PMID:26062544 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Casp1 caspase 1 multiple interactions EXP Rutin inhibits the reaction [Fructose results in increased expression of CASP1 protein] CTD PMID:22426011 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 affects cleavage
increases cleavage
multiple interactions
increases expression
increases activity
ISO
EXP
Rutin affects the cleavage of CASP3 protein
Rutin results in increased cleavage of CASP3 protein
Rutin inhibits the reaction [Cholesterol, Dietary results in increased cleavage of CASP3 protein]; Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of CASP3 mRNA]; Rutin inhibits the reaction [Oxidopamine results in increased expression of CASP3 mRNA]
[Rutin binds to Zinc] which results in increased expression of CASP3 mRNA; [Rutin co-treated with Meloxicam] affects the reaction [Formaldehyde affects the expression of CASP3 protein]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]; Rutin inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]
Rutin results in increased expression of CASP3 mRNA
Rutin results in increased activity of CASP3 protein
CTD PMID:15975156 PMID:24726691 PMID:24908156 PMID:25129099 PMID:26091902 PMID:27239252 PMID:28811126 PMID:29315975 PMID:29522708 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
ISO
EXP
Rutin results in increased activity of CASP7 protein
Rutin inhibits the reaction [Oxidopamine results in increased expression of CASP7 mRNA]
CTD PMID:24726691 PMID:25129099 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
ISO [Rutin binds to Zinc] which results in increased expression of CASP8 mRNA
Rutin results in increased expression of CASP8 mRNA
CTD PMID:26091902 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions ISO
EXP
Rutin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]
Rutin inhibits the reaction [Lipopolysaccharides results in decreased activity of CAT protein]
Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAT mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAT protein]; Rutin inhibits the reaction [Cisplatin results in decreased expression of CAT protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]
CTD PMID:19833193 PMID:21605616 PMID:25478064 PMID:25753322 PMID:29743444 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr1 carbonyl reductase 1 multiple interactions ISO Rutin binds to and results in decreased activity of CBR1 protein; Rutin inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:11306090 PMID:18579125 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
decreases expression
ISO
EXP
Rutin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]
Rutin results in decreased secretion of CCL2 protein
Rutin results in decreased expression of CCL2 mRNA
CTD PMID:21756928 PMID:21967610 PMID:25478064 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases expression
EXP Lipopolysaccharides inhibits the reaction [Rutin results in decreased expression of CCL5 mRNA] CTD PMID:28693884 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions EXP Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein] CTD PMID:24117263 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO [Rutin binds to Zinc] which results in decreased expression of CCND1 mRNA
Rutin results in decreased expression of CCND1 mRNA
CTD PMID:26091902 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd68 Cd68 molecule decreases expression EXP Rutin results in decreased expression of CD68 protein CTD PMID:28693884 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Rutin inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 mRNA] CTD PMID:15652231 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 decreases expression EXP Rutin results in decreased expression of CX3CL1 mRNA CTD PMID:28693884 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
decreases secretion
decreases expression
ISO Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]
Rutin results in decreased secretion of CXCL10 protein
Rutin results in decreased expression of CXCL10 mRNA
CTD PMID:21756928 PMID:21967610 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression
multiple interactions
EXP Rutin results in decreased expression of CXCL12 mRNA
Lipopolysaccharides inhibits the reaction [Rutin results in decreased expression of CXCL12 mRNA]
CTD PMID:28693884 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression EXP Rutin results in increased expression of CYP19A1 protein CTD PMID:29899696 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Rutin results in increased expression of CYP1A1 mRNA CTD PMID:21756928 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Rutin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Egf epidermal growth factor multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of EGF mRNA] CTD PMID:26062544 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Rutin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Esr2 estrogen receptor 2 increases expression EXP Rutin results in increased expression of ESR2 protein CTD PMID:29899696 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fadd Fas associated via death domain multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of FADD mRNA] CTD PMID:26062544 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions
ISO
EXP
Rutin results in increased expression of FN1 protein
Rutin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]
CTD PMID:24117263 PMID:26408079 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Rutin inhibits the reaction [oxaliplatin results in increased expression of FOS protein] CTD PMID:24908156 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fshr follicle stimulating hormone receptor increases expression EXP Rutin results in increased expression of FSHR protein CTD PMID:29899696 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Gdnf glial cell derived neurotrophic factor increases expression EXP Rutin results in increased expression of GDNF mRNA CTD PMID:28693884 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein]; Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of GPT protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein] CTD PMID:25478064 PMID:25753322 PMID:26062544 PMID:27239252 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of GPX1 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of GPX1 protein] CTD PMID:25478064 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
ISO
EXP
Rutin results in decreased activity of GSR protein
Rutin inhibits the reaction [Cisplatin results in decreased expression of GSR protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]
CTD PMID:15782287 PMID:21605616 PMID:25753322 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Rutin co-treated with Carbon Tetrachloride] results in increased expression of HMOX1 protein CTD PMID:22902988 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifng interferon gamma multiple interactions ISO Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:21756928 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP [Lipopolysaccharides co-treated with Rutin] results in decreased expression of IGF1 mRNA CTD PMID:28693884 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IGF1R protein] CTD PMID:20015448 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
EXP Lipopolysaccharides promotes the reaction [Rutin results in increased expression of IL10 mRNA]
Rutin results in increased expression of IL10 mRNA; Rutin results in increased expression of IL10 protein
CTD PMID:28693884 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il18 interleukin 18 multiple interactions
decreases expression
EXP Rutin inhibits the reaction [Fructose results in increased expression of IL18 protein]
Rutin results in decreased expression of IL18 mRNA
CTD PMID:22426011 PMID:28693884 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO
EXP
Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; Rutin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of IL1B protein]
Rutin results in decreased expression of IL1B mRNA
Lipopolysaccharides inhibits the reaction [Rutin results in decreased expression of IL1B mRNA]; Rutin inhibits the reaction [Fructose results in increased expression of IL1B protein]
[Rutin co-treated with Meloxicam] affects the reaction [Formaldehyde affects the expression of IL1B protein]; Rutin affects the reaction [Formaldehyde affects the expression of IL1B protein]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]
CTD PMID:15652231 PMID:18958421 PMID:19557821 PMID:22426011 PMID:28693884 PMID:29315975 PMID:29522708 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO
EXP
Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Rutin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
Rutin results in decreased expression of IL6 mRNA; Rutin results in decreased expression of IL6 protein
Lipopolysaccharides inhibits the reaction [Rutin results in decreased expression of IL6 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Rutin inhibits the reaction [Fructose results in increased expression of IL6 protein]
Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD PMID:15652231 PMID:18958421 PMID:21756928 PMID:22426011 PMID:25753322 PMID:26062544 PMID:27239252 PMID:28693884 PMID:29743444 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insr insulin receptor multiple interactions EXP Rutin inhibits the reaction [Fructose results in decreased phosphorylation of INSR protein] CTD PMID:22426011 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression
multiple interactions
ISO
EXP
Rutin results in decreased expression of IRS1 protein
Rutin inhibits the reaction [Fructose results in decreased phosphorylation of IRS1 protein]
Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IRS1 protein]; Vitamin E results in increased susceptibility to [Rutin results in decreased expression of IRS1 protein]
CTD PMID:20015448 PMID:22426011 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
EXP Rutin results in increased expression of ITGAM protein
Lipopolysaccharides inhibits the reaction [Rutin results in increased expression of ITGAM protein]
CTD PMID:28693884 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Jak1 Janus kinase 1 multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of JAK1 mRNA] CTD PMID:26062544 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jak2 Janus kinase 2 multiple interactions EXP Rutin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein] CTD PMID:22426011 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO Rutin results in decreased expression of JUN protein
Rutin results in increased susceptibility to [Vitamin E results in decreased expression of JUN protein]; Vitamin E results in increased susceptibility to [Rutin results in decreased expression of JUN protein]
CTD PMID:20015448 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Lamb2 laminin subunit beta 2 increases expression ISO Rutin results in increased expression of LAMB2 protein CTD PMID:26408079 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Lep leptin multiple interactions EXP Rutin inhibits the reaction [Fructose results in increased expression of LEP protein] CTD PMID:22426011 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor multiple interactions EXP Rutin inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein] CTD PMID:22426011 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lgals9 galectin 9 multiple interactions EXP Rutin inhibits the reaction [Fructose results in decreased expression of LGALS9 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of LGALS9 protein] CTD PMID:19605544 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of MAP2K5 mRNA] CTD PMID:26062544 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO
EXP
Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK1 protein]
Rutin inhibits the reaction [Fructose results in decreased phosphorylation of MAPK1 protein]
Rutin results in decreased phosphorylation of MAPK1 protein
CTD PMID:19557821 PMID:21756928 PMID:22426011 PMID:29522708 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO
EXP
Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK3 protein]
Rutin inhibits the reaction [Fructose results in decreased phosphorylation of MAPK3 protein]
Rutin results in decreased phosphorylation of MAPK3 protein
CTD PMID:19557821 PMID:21756928 PMID:22426011 PMID:29522708 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Rutin results in decreased expression of and results in decreased activity of MMP2 protein
Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP2 protein]
CTD PMID:26408079 PMID:29743444 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
ISO Rutin results in decreased expression of MMP9 mRNA
Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP9 protein]
CTD PMID:16304905 PMID:29743444 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression
multiple interactions
EXP Rutin results in increased expression of MRC1 protein
[Lipopolysaccharides co-treated with Rutin] results in increased expression of MRC1 protein
CTD PMID:28693884 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO
EXP
Rutin promotes the reaction [Carbon Tetrachloride results in increased expression of NFE2L2 protein]
[Rutin co-treated with Hydrogen Peroxide] affects the localization of NFE2L2 protein
CTD PMID:22902988 PMID:31412289 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Rutin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein] CTD PMID:19557821 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Rutin inhibits the reaction [Fructose results in increased expression of NLRP3 protein] CTD PMID:22426011 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP
ISO
Rutin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
Rutin results in decreased expression of NOS2 mRNA; Rutin results in decreased expression of NOS2 protein
Rutin inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; Rutin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD PMID:11500931 PMID:12512693 PMID:22902988 PMID:25080890 PMID:25753322 PMID:28693884 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr14:77,380,264...77,402,007
Ensembl chr14:77,380,262...77,401,996
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression ISO Rutin results in decreased expression of PNPLA3 mRNA CTD PMID:17032037 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
increases expression
EXP Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON1 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON1 protein]
Rutin results in increased expression of PON1 mRNA
CTD PMID:25478064 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon3 paraoxonase 3 multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON3 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON3 protein] CTD PMID:25478064 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP Rutin inhibits the reaction [Fructose results in decreased expression of PPARA protein] CTD PMID:22426011 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARD mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARD protein] CTD PMID:25478064 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
ISO
EXP
[Rutin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTGS2 mRNA; Rutin inhibits the reaction [Glucose results in increased expression of PTGS2 mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of PTGS2 protein]
Rutin results in decreased expression of PTGS2 mRNA
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; Rutin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Rutin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
CTD PMID:11500931 PMID:15652231 PMID:19557821 PMID:21756928 PMID:22902988 PMID:25080890 PMID:25753322 PMID:28693884 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP Rutin inhibits the reaction [Fructose results in increased expression of PYCARD protein] CTD PMID:22426011 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Rutin inhibits the reaction [Glucose affects the localization of RELA protein]; Rutin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]
Rutin inhibits the reaction [Carbon Tetrachloride affects the localization of RELA protein]
CTD PMID:19557821 PMID:21756928 PMID:29522708 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sirt1 sirtuin 1 increases expression EXP Rutin results in increased expression of SIRT1 mRNA; Rutin results in increased expression of SIRT1 protein CTD PMID:30365940 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 increases expression
multiple interactions
EXP Rutin results in increased expression of SLAMF1 protein
Lipopolysaccharides inhibits the reaction [Rutin results in increased expression of SLAMF1 protein]
CTD PMID:28693884 NCBI chr13:90,184,545...90,219,170
Ensembl chr13:90,184,569...90,219,217
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions EXP Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A1 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A1 protein] CTD PMID:19605544 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions EXP Rutin inhibits the reaction [Fructose results in increased expression of SLC22A12 mRNA]; Rutin inhibits the reaction [Fructose results in increased expression of SLC22A12 protein] CTD PMID:19605544 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions EXP Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A2 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A2 protein] CTD PMID:19605544 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions EXP Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A6 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A6 protein] CTD PMID:19605544 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc2a9 solute carrier family 2 member 9 multiple interactions EXP Rutin inhibits the reaction [Fructose results in increased expression of SLC2A9 mRNA SNP]; Rutin inhibits the reaction [Fructose results in increased expression of SLC2A9 protein SNP] CTD PMID:19605544 NCBI chr14:77,067,537...77,192,702
Ensembl chr14:77,067,503...77,192,702
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO Rutin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein] CTD PMID:22394605 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 affects localization
multiple interactions
ISO Rutin affects the localization of SLCO2B1 protein
Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of Cholic Acid]; Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of estrone sulfate]; Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of Rosuvastatin Calcium]; Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of Taurocholic Acid]
CTD PMID:24285294 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Smad2 SMAD family member 2 multiple interactions EXP Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of SMAD2 mRNA] CTD PMID:27239252 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad4 SMAD family member 4 multiple interactions EXP Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of SMAD4 mRNA] CTD PMID:27239252 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP Rutin inhibits the reaction [Fructose results in increased expression of SOCS3 protein] CTD PMID:22426011 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in decreased activity of SOD1 protein] CTD PMID:22902988 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions ISO [Rutin co-treated with Meloxicam] inhibits the reaction [Formaldehyde affects the activity of SORD protein]; Rutin inhibits the reaction [Formaldehyde affects the activity of SORD protein] CTD PMID:29315975 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Star steroidogenic acute regulatory protein increases expression EXP Rutin results in increased expression of STAR protein CTD PMID:29899696 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of STAT3 mRNA]; Rutin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein] CTD PMID:22426011 PMID:26062544 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO Rutin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO
EXP
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]
Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of TGFB1 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of TGFB1 mRNA]
CTD PMID:22902988 PMID:24117263 PMID:27239252 PMID:28693884 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]; Rutin inhibits the reaction [Glucose results in increased expression of TNF mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of TNF protein]
Rutin results in decreased expression of TNF mRNA; Rutin results in decreased expression of TNF protein
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
Rutin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Rutin inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Rutin inhibits the reaction [Fructose results in increased expression of TNF protein]
CTD PMID:14654164 PMID:18958421 PMID:19557821 PMID:21605616 PMID:21756928 PMID:22426011 PMID:22902988 PMID:25753322 PMID:28693884 PMID:29743444 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP
ISO
Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of TP53 mRNA]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of TRP53 protein]
CTD PMID:27239252 PMID:29522708 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP Rutin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Rutin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 protein] CTD PMID:25080890 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
ISO Rutin results in decreased secretion of and results in decreased expression of VEGFA protein; Rutin results in increased susceptibility to [Vitamin E results in decreased expression of VEGFA mRNA]; Rutin results in increased susceptibility to [Vitamin E results in decreased secretion of and results in decreased expression of VEGFA protein]; Vitamin E results in increased susceptibility to [Rutin results in decreased expression of VEGFA mRNA]; Vitamin E results in increased susceptibility to [Rutin results in decreased secretion of and results in decreased expression of VEGFA protein] CTD PMID:20015448 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP Rutin inhibits the reaction [Cyclophosphamide results in increased activity of XDH protein] CTD PMID:25753322 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      chemical role 19351
        antioxidant 14255
          quercetin 4003
            quercetin O-glycoside 423
              avicularin 0
              hermannioside A 0
              miquelianin 33
              quercetin 3,7-di-O-alpha-L-rhamnoside 0
              quercetin 3-(6''-p-hydroxybenzoylgalactoside) 0
              quercetin 3-O-(2'',3''-digalloyl)-beta-D-galactopyranoside 0
              quercetin 3-O-[alpha-L-rhamnopyranosyl(1->2)-beta-D-galactopyranosyl]-7-O-alpha-L-rhamnopyranoside 0
              quercetin 3-O-alpha-(6'''-caffeoylglucosyl-beta-1,2-rhamnoside) 0
              quercetin 3-O-alpha-D-rhamnofuranoside 0
              quercetin 3-O-alpha-L-fucopyranoside 0
              quercetin 3-O-alpha-L-rhamnofuranoside 0
              quercetin 3-O-alpha-L-rhamnopyranosyl-(1->2)-alpha-L-arabinopyranoside 0
              quercetin 3-O-arabinoside 7-O-rhamnoside 0
              quercetin 3-O-beta-D-fucopyranoside 0
              quercetin 3-O-beta-D-galactopyranoside + 36
              quercetin 3-O-beta-D-glucopyranosyl-(1->2)-rhamnopyranoside 0
              quercetin 3-O-beta-L-fucopyranoside 0
              quercetin 3-O-beta-L-rhamnofuranoside 0
              quercetin 3-beta-gentiobioside 0
              quercetin 3-beta-gentiotrioside 0
              quercetin 4'-O-alpha-L-rhamnopyranosyl-3-O-beta-D-allopyranoside 0
              quercetin 7-O-alpha-D-rhamnopyranoside 0
              quercetin 7-O-alpha-L-rhamnopyranoside 0
              quercetin 7-O-beta-L-rhamnopyranoside 0
              quercetin O-glucoside + 161
              quercetin-3-O-alpha-D-arabinofuranoside 0
              quercetin-3-O-arabinoside 0
              quercetin-3-O-beta-D-xylopyranoside 0
              quercetin-7-O-[alpha-L-rhamnopyranosyl(1->6)-beta-D-galactopyranoside] 0
              quercitrin 242
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic molecule 19596
                              organic cyclic compound 19407
                                organic heterocyclic compound 18517
                                  oxacycle 17299
                                    benzopyran 10156
                                      1-benzopyran 9872
                                        flavonoid 6379
                                          flavones 4174
                                            hydroxyflavone 4162
                                              flavonols 4076
                                                7-hydroxyflavonol 4055
                                                  quercetin 4003
                                                    quercetin O-glycoside 423
                                                      avicularin 0
                                                      hermannioside A 0
                                                      miquelianin 33
                                                      quercetin 3,7-di-O-alpha-L-rhamnoside 0
                                                      quercetin 3-(6''-p-hydroxybenzoylgalactoside) 0
                                                      quercetin 3-O-(2'',3''-digalloyl)-beta-D-galactopyranoside 0
                                                      quercetin 3-O-[alpha-L-rhamnopyranosyl(1->2)-beta-D-galactopyranosyl]-7-O-alpha-L-rhamnopyranoside 0
                                                      quercetin 3-O-alpha-(6'''-caffeoylglucosyl-beta-1,2-rhamnoside) 0
                                                      quercetin 3-O-alpha-D-rhamnofuranoside 0
                                                      quercetin 3-O-alpha-L-fucopyranoside 0
                                                      quercetin 3-O-alpha-L-rhamnofuranoside 0
                                                      quercetin 3-O-alpha-L-rhamnopyranosyl-(1->2)-alpha-L-arabinopyranoside 0
                                                      quercetin 3-O-arabinoside 7-O-rhamnoside 0
                                                      quercetin 3-O-beta-D-fucopyranoside 0
                                                      quercetin 3-O-beta-D-galactopyranoside + 36
                                                      quercetin 3-O-beta-D-glucopyranosyl-(1->2)-rhamnopyranoside 0
                                                      quercetin 3-O-beta-L-fucopyranoside 0
                                                      quercetin 3-O-beta-L-rhamnofuranoside 0
                                                      quercetin 3-beta-gentiobioside 0
                                                      quercetin 3-beta-gentiotrioside 0
                                                      quercetin 4'-O-alpha-L-rhamnopyranosyl-3-O-beta-D-allopyranoside 0
                                                      quercetin 7-O-alpha-D-rhamnopyranoside 0
                                                      quercetin 7-O-alpha-L-rhamnopyranoside 0
                                                      quercetin 7-O-beta-L-rhamnopyranoside 0
                                                      quercetin O-glucoside + 161
                                                      quercetin-3-O-alpha-D-arabinofuranoside 0
                                                      quercetin-3-O-arabinoside 0
                                                      quercetin-3-O-beta-D-xylopyranoside 0
                                                      quercetin-7-O-[alpha-L-rhamnopyranosyl(1->6)-beta-D-galactopyranoside] 0
                                                      quercitrin 242
paths to the root