|
G |
Mir224 |
microRNA 224 |
decreases expression |
ISO |
C646 decreased expression of miR244 in a human hepatocellular carcinoma cell line |
RGD |
PMID:22459148 |
RGD:18182922 |
NCBI chr X:150,065,088...150,065,169
|
|
|
G |
Ar |
androgen receptor |
multiple interactions |
ISO |
Pentamidine binds to and results in decreased activity of AR protein |
CTD |
PMID:25752796 |
|
NCBI chr X:63,104,771...63,273,934
|
|
G |
Asic5 |
acid sensing ion channel subunit family member 5 |
decreases activity |
ISO |
Pentamidine results in decreased activity of ASIC5 protein |
CTD |
PMID:21828194 |
|
NCBI chr 2:167,307,984...167,336,812
|
|
G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
ISO |
Pentamidine results in increased expression of ASNS mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 4:36,752,061...36,769,970
|
|
G |
Atm |
ATM serine/threonine kinase |
affects localization decreases activity |
ISO |
Pentamidine affects the localization of ATM protein modified form Pentamidine results in decreased activity of ATM protein |
CTD |
PMID:20144237 |
|
NCBI chr 8:62,724,939...62,829,040
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases activity |
ISO |
Pentamidine results in decreased activity of CYP1B1 protein |
CTD |
PMID:33814510 |
|
NCBI chr 6:21,093,927...21,103,091
|
|
G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
decreases activity |
ISO |
Pentamidine results in decreased activity of CYP2C19 protein |
CTD |
PMID:11124226 |
|
NCBI chr 1:247,879,058...247,916,804
|
|
G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
decreases activity |
ISO |
Pentamidine results in decreased activity of CYP2D6 protein |
CTD |
PMID:11124226 |
|
NCBI chr 7:115,762,662...115,771,832
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases activity |
ISO |
Pentamidine results in decreased activity of CYP3A4 protein |
CTD |
PMID:11124226 |
|
NCBI chr12:14,321,771...14,343,886
|
|
G |
Depp1 |
DEPP autophagy regulator 1 |
increases expression |
ISO |
Pentamidine results in increased expression of DEPP1 mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 4:149,910,794...149,913,013
|
|
G |
Fabp1 |
fatty acid binding protein 1 |
decreases expression |
ISO |
Pentamidine results in decreased expression of FABP1 mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 4:104,744,302...104,753,119
|
|
G |
Fndc4 |
fibronectin type III domain containing 4 |
increases expression |
ISO |
Pentamidine results in increased expression of FNDC4 mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 6:25,077,155...25,080,812
|
|
G |
H2ax |
H2A.X variant histone |
affects localization |
ISO |
Pentamidine affects the localization of H2AX protein modified form |
CTD |
PMID:20144237 |
|
NCBI chr 8:53,568,718...53,570,072
|
|
G |
Hpn |
hepsin |
increases expression |
ISO |
Pentamidine results in increased expression of HPN mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 1:86,337,085...86,352,785
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
[Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA |
CTD |
PMID:15588918 PMID:29594315 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Ifngr1 |
interferon gamma receptor 1 |
increases expression |
ISO |
Pentamidine results in increased expression of IFNGR1 mRNA; Pentamidine results in increased expression of IFNGR1 protein |
CTD |
PMID:12803856 |
|
NCBI chr 1:16,152,811...16,171,439
|
|
G |
Il10 |
interleukin 10 |
multiple interactions decreases expression |
ISO |
[Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein Pentamidine results in decreased expression of IL10 protein |
CTD |
PMID:15588918 |
|
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il1b |
interleukin 1 beta |
decreases expression |
ISO |
Pentamidine results in decreased expression of IL1B mRNA |
CTD |
PMID:29594315 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
[Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA |
CTD |
PMID:15588918 PMID:29594315 |
|
NCBI chr 2:121,932,968...121,937,672
|
|
G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
[Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein |
CTD |
PMID:15588918 |
|
NCBI chr10:38,272,003...38,277,549
|
|
G |
Inhbe |
inhibin subunit beta E |
increases expression |
ISO |
Pentamidine results in increased expression of INHBE mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 7:65,061,531...65,064,519
|
|
G |
Kat5 |
lysine acetyltransferase 5 |
multiple interactions decreases activity |
ISO |
Pentamidine inhibits the reaction [KAT5 protein results in increased acetylation of TP53 protein] Pentamidine results in decreased activity of KAT5 protein |
CTD |
PMID:20144237 |
|
NCBI chr 1:212,325,089...212,332,640
|
|
G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
multiple interactions decreases activity |
ISO |
Pentamidine affects the localization of and affects the activity of KCNH2 protein; Pentamidine affects the localization of and results in decreased activity of KCNH2 protein; Pentamidine inhibits the reaction [KCNH2 protein results in increased transport of Thallium] Pentamidine results in decreased activity of KCNH2 protein |
CTD |
PMID:15340016 PMID:15711590 PMID:21158687 |
|
NCBI chr 4:11,719,357...11,751,424
|
|
G |
Lss |
lanosterol synthase |
decreases expression |
ISO |
Pentamidine results in decreased expression of LSS mRNA |
CTD |
PMID:15342952 |
|
NCBI chr20:12,090,641...12,118,230
|
|
G |
Mre11 |
MRE11 homolog, double strand break repair nuclease |
decreases activity |
ISO |
Pentamidine results in decreased activity of MRE11 protein |
CTD |
PMID:20144237 |
|
NCBI chr 8:19,900,211...19,961,906
|
|
G |
Nbn |
nibrin |
affects localization |
ISO |
Pentamidine affects the localization of NBN protein |
CTD |
PMID:20144237 |
|
NCBI chr 5:34,256,678...34,291,163
|
|
G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
increases expression |
ISO |
Pentamidine results in increased expression of NR0B2 mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 5:145,779,294...145,782,609
|
|
G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
increases activity |
ISO |
Pentamidine results in increased activity of NR1H4 protein |
CTD |
PMID:22414727 |
|
NCBI chr 7:25,733,471...25,829,440
|
|
G |
Nupr1 |
nuclear protein 1, transcriptional regulator |
increases expression |
ISO |
Pentamidine results in increased expression of NUPR1 mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 1:190,643,866...190,645,901
|
|
G |
RT1-Bb |
RT1 class II, locus Bb |
affects expression |
ISO |
Pentamidine affects the expression of HLA-DQB1 mRNA |
CTD |
PMID:25811541 |
|
NCBI chr20:4,598,475...4,604,118
|
|
G |
Serpina3n |
serpin family A member 3N |
increases expression |
ISO |
Pentamidine results in increased expression of SERPINA3 mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 6:123,323,623...123,331,181
|
|
G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
Pentamidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
|
|
G |
Slc2a3 |
solute carrier family 2 member 3 |
decreases expression |
ISO |
Pentamidine results in decreased expression of SLC2A3 mRNA |
CTD |
PMID:15342952 |
|
NCBI chr 4:157,632,887...157,698,034
|
|
G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
Pentamidine inhibits the reaction [KAT5 protein results in increased acetylation of TP53 protein] |
CTD |
PMID:20144237 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Wipi1 |
WD repeat domain, phosphoinositide interacting 1 |
increases expression |
ISO |
Pentamidine results in increased expression of WIPI1 mRNA |
CTD |
PMID:15342952 |
|
NCBI chr10:95,042,451...95,079,679
|
|
|
G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with procyanidin B3 co-treated with Lipopolysaccharides] results in increased expression of AGER mRNA |
CTD |
PMID:22169119 |
|
NCBI chr20:4,152,758...4,155,956
|
|
G |
Aqp3 |
aquaporin 3 (Gill blood group) |
multiple interactions |
ISO |
[[procyanidin B1 co-treated with procyanidin B3] co-treated with Catechin] results in increased expression of AQP3 mRNA |
CTD |
PMID:33294640 |
|
NCBI chr 5:61,035,165...61,040,683
|
|
G |
Cat |
catalase |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with procyanidin B3 co-treated with Lipopolysaccharides] results in increased expression of CAT mRNA |
CTD |
PMID:22169119 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr10:67,503,077...67,504,875
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr10:68,820,330...68,824,906
|
|
G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions |
ISO |
[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of CCL7 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr10:67,514,095...67,515,945
|
|
G |
Cd80 |
Cd80 molecule |
multiple interactions |
ISO |
procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr11:75,760,073...75,798,978
|
|
G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr10:38,887,692...38,889,673
|
|
G |
Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of FAS mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr 1:241,212,155...241,245,774
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with procyanidin B3 co-treated with Lipopolysaccharides] results in increased expression of GCLM mRNA |
CTD |
PMID:22169119 |
|
NCBI chr 2:213,032,135...213,052,192
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with procyanidin B3] promotes the reaction [Lipopolysaccharides results in increased expression of HMOX1 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr10:29,390,300...29,405,194
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il2ra |
interleukin 2 receptor subunit alpha |
multiple interactions |
ISO |
procyanidin B3 promotes the reaction [Lipopolysaccharides results in increased expression of IL2RA mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr17:66,849,974...66,898,665
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with procyanidin B3] inhibits the reaction [Lipopolysaccharides results in increased expression of MAP3K8 mRNA]; procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of MAP3K8 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr17:58,078,175...58,098,455
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein; Eicosapentaenoic Acid promotes the reaction [[Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein]; procyanidin B3 promotes the reaction [[Lipopolysaccharides co-treated with Eicosapentaenoic Acid] results in decreased phosphorylation of MAPK8 protein] |
CTD |
PMID:22169119 |
|
NCBI chr16:8,645,171...8,728,225
|
|
G |
Msr1 |
macrophage scavenger receptor 1 |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with procyanidin B3] promotes the reaction [Lipopolysaccharides results in increased expression of MSR1 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr16:52,717,775...52,803,602
|
|
G |
Nfkb2 |
nuclear factor kappa B subunit 2 |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with procyanidin B3] inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB2 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr 1:255,106,010...255,114,649
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
procyanidin B3 inhibits the reaction [[Lipopolysaccharides co-treated with Eicosapentaenoic Acid] results in increased phosphorylation of RELA protein] |
CTD |
PMID:22169119 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO |
[procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr12:25,237,977...25,248,356
|
|
G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions |
ISO |
procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF1B mRNA] |
CTD |
PMID:22169119 |
|
NCBI chr 5:157,070,642...157,104,216
|
|