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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-nitro-p-phenylenediamine
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Accession:CHEBI:76394 term browser browse the term
Definition:A primary amino compound that is p-phenylenediamine in which one of the hydrogens attached to the benzene ring is replaced by a nitro group. It is a cosmetic hair dye intermediate that is used in permanent hair colouring products (diluted 1:1 with an oxidising agent prior to application).
Synonyms:exact_synonym: 2-nitrobenzene-1,4-diamine
 related_synonym: 1,4-Diaminonitrobenzol;   1,4-diamino-2-nitrobenzene;   2,5-diaminonitrobenzene;   2-NPPD;   2-nitro-1,4-benzenediamine;   2-nitro-1,4-diaminobenzene;   2-nitro-1,4-phenylenediamine;   2-nitro-4-aminoaniline;   2-nitro-4-phenylenediamine;   2NDB;   4-amino-2-nitroaniline;   C.I. 76070;   CI 76070;   Formula=C6H7N3O2;   InChI=1S/C6H7N3O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,7-8H2;   InChIKey=HVHNMNGARPCGGD-UHFFFAOYSA-N;   SMILES=Nc1ccc(N)c(c1)[N+]([O-])=O;   nitro-p-phenylenediamine;   o-nitro-p-phenylenediamine
 xref: CAS:5307-14-2;   KEGG:C19385
 xref_mesh: MESH:C014706
 xref: PMID:10873714;   PMID:12799694;   PMID:19469988;   PMID:2049801;   PMID:3594688;   PMID:520983;   PMID:6827626;   PMID:7327475;   PMID:7330774;   PMID:9465934;   Reaxys:2210195



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2-nitro-p-phenylenediamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of ABCB1B mRNA CTD PMID:17070881 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Aen apoptosis enhancing nuclease increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of AEN mRNA CTD PMID:17070881 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of ALDH1A4 mRNA CTD PMID:17070881 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of BAX mRNA CTD PMID:17070881 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of BTG2 mRNA CTD PMID:17070881 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C7 complement C7 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G Cblc Cbl proto-oncogene C decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
JBrowse link
G Ccng1 cyclin G1 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of CCNG1 mRNA CTD PMID:17070881 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd276 Cd276 molecule increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of CD276 mRNA CTD PMID:17070881 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of CDKN1A mRNA CTD PMID:17070881 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cryab crystallin, alpha B increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of EPCAM mRNA CTD PMID:17070881 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of EPHX1 mRNA CTD PMID:17070881 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of FAS mRNA CTD PMID:17070881 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of GRIA3 mRNA CTD PMID:17070881 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of MGMT mRNA CTD PMID:17070881 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of NUPR1 mRNA CTD PMID:17070881 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Olr37 olfactory receptor 37 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of OLR37 mRNA CTD PMID:17070881 NCBI chr 1:154,089,219...154,090,184 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Slc16a10 solute carrier family 16 member 10 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376
JBrowse link
G Sulf2 sulfatase 2 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of SULF2 mRNA CTD PMID:17070881 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP 2-nitro-4-phenylenediamine results in increased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Zmat3 zinc finger, matrin type 3 decreases expression EXP 2-nitro-4-phenylenediamine results in decreased expression of ZMAT3 mRNA CTD PMID:17070881 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      application 19467
        reagent 17473
          1,4-phenylenediamine 165
            2-nitro-p-phenylenediamine 43
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    main group molecular entity 19704
                      s-block molecular entity 19489
                        hydrogen molecular entity 19484
                          hydrides 18841
                            inorganic hydride 17688
                              pnictogen hydride 17669
                                nitrogen hydride 17542
                                  azane 17278
                                    ammonia 17277
                                      organic amino compound 17277
                                        polyamine 8266
                                          diamine 8195
                                            primary diamine 5673
                                              phenylenediamine 2659
                                                1,4-phenylenediamine 165
                                                  2-nitro-p-phenylenediamine 43
paths to the root