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G |
Mt1 |
metallothionein 1 |
increases expression |
ISO |
3-tert-butyl-4-hydroxyanisole results in increased expression of MT1 mRNA |
CTD |
PMID:14998373 |
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NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions increases expression |
ISO |
[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA Butylated Hydroxyanisole results in increased expression of ABCC2 mRNA Butylated Hydroxyanisole results in increased expression of ABCC2 mRNA; Butylated Hydroxyanisole results in increased expression of ABCC2 protein |
CTD |
PMID:15833929 PMID:16426233 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
multiple interactions increases expression |
ISO |
[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA Butylated Hydroxyanisole results in increased expression of ABCC3 mRNA |
CTD |
PMID:15833929 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
increases expression multiple interactions |
ISO |
Butylated Hydroxyanisole results in increased expression of ABCC4 mRNA [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNA |
CTD |
PMID:15833929 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
multiple interactions increases expression |
ISO |
[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC5 mRNA Butylated Hydroxyanisole results in increased expression of ABCC5 mRNA |
CTD |
PMID:15833929 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
multiple interactions increases expression |
ISO |
[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC6 mRNA Butylated Hydroxyanisole results in increased expression of ABCC6 mRNA |
CTD |
PMID:15833929 |
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NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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G |
Aco1 |
aconitase 1 |
multiple interactions |
EXP |
Butylated Hydroxyanisole inhibits the reaction [Cadmium Chloride affects the localization of ACO1 protein] |
CTD |
PMID:25106854 |
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NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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G |
Ahr |
aryl hydrocarbon receptor |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of AHR mRNA |
CTD |
PMID:17627975 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Akr7a3 |
aldo-keto reductase family 7 member A3 |
increases expression |
EXP |
Butylated Hydroxyanisole results in increased expression of AKR7A3 protein |
CTD |
PMID:8198522 |
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NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:17998271 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Aldh1a2 |
aldehyde dehydrogenase 1 family, member A2 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of ALDH1A2 mRNA |
CTD |
PMID:28927898 |
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NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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G |
Aldh1b1 |
aldehyde dehydrogenase 1 family, member B1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of ALDH1B1 mRNA |
CTD |
PMID:17998271 |
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NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
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G |
Aldh3a1 |
aldehyde dehydrogenase 3 family, member A1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of ALDH3A1 mRNA |
CTD |
PMID:17998271 |
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NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
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G |
Aldh4a1 |
aldehyde dehydrogenase 4 family, member A1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of ALDH4A1 mRNA |
CTD |
PMID:17998271 |
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NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345
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G |
Aldh7a1 |
aldehyde dehydrogenase 7 family, member A1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of ALDH7A1 mRNA |
CTD |
PMID:17998271 |
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NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
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G |
Aldh8a1 |
aldehyde dehydrogenase 8 family, member A1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of ALDH8A1 mRNA |
CTD |
PMID:17998271 |
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NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
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G |
Ar |
androgen receptor |
affects binding multiple interactions |
ISO |
Butylated Hydroxyanisole binds to AR protein Butylated Hydroxyanisole inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Butylated Hydroxyanisole inhibits the reaction [Dihydrotestosterone binds to AR protein] |
CTD |
PMID:10696776 PMID:14579009 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Atp6v1a |
ATPase H+ transporting V1 subunit A |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of ATP6V1A protein] Butylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of ATP6V1A protein] |
CTD |
PMID:12470298 |
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NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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G |
Aurkb |
aurora kinase B |
increases expression |
EXP |
Butylated Hydroxyanisole results in increased expression of AURKB protein |
CTD |
PMID:23535288 |
|
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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G |
Car1 |
carbonic anhydrase 1 |
decreases activity |
ISO |
Butylated Hydroxyanisole results in decreased activity of CA1 protein |
CTD |
PMID:19231207 |
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NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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G |
Car13 |
carbonic anhydrase 13 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of CAR13 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525
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G |
Car2 |
carbonic anhydrase 2 |
decreases activity |
ISO |
Butylated Hydroxyanisole results in decreased activity of CA2 protein |
CTD |
PMID:19231207 |
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NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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G |
Casp3 |
caspase 3 |
multiple interactions decreases activity |
ISO |
[Butylated Hydroxyanisole co-treated with Butylated Hydroxytoluene] results in decreased activity of CASP3 protein; Butylated Hydroxyanisole inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP3 protein]; Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased activity of CASP3 protein] Butylated Hydroxyanisole results in decreased activity of CASP3 protein |
CTD |
PMID:14981915 PMID:16407847 PMID:21843585 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein] |
CTD |
PMID:21843585 |
|
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Cat |
catalase |
multiple interactions |
EXP |
Butylated Hydroxyanisole inhibits the reaction [Estradiol results in increased activity of CAT protein]; Butylated Hydroxyanisole inhibits the reaction [tetrabromobisphenol A results in decreased activity of CAT protein] |
CTD |
PMID:19526586 PMID:27718046 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cbr1 |
carbonyl reductase 1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of CBR1 mRNA; Butylated Hydroxyanisole results in increased expression of CBR1 protein |
CTD |
PMID:23247010 |
|
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Cbx5 |
chromobox 5 |
increases expression |
EXP |
Butylated Hydroxyanisole results in increased expression of CBX5 protein |
CTD |
PMID:23535288 |
|
NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
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G |
Ccnb1 |
cyclin B1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of CCNB1 mRNA |
CTD |
PMID:19000923 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Cdk1 |
cyclin-dependent kinase 1 |
increases expression |
EXP |
Butylated Hydroxyanisole results in increased expression of CDK1 protein |
CTD |
PMID:23535288 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions |
ISO |
Butylated Hydroxyanisole results in increased expression of CDKN1A mRNA Hydrogen Peroxide promotes the reaction [Butylated Hydroxyanisole results in increased expression of CDKN1A mRNA] |
CTD |
PMID:29486183 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdx1 |
caudal type homeo box 1 |
affects expression |
ISO |
Butylated Hydroxyanisole affects the expression of CDX1 mRNA |
CTD |
PMID:28927898 |
|
NCBI chr18:54,472,587...54,490,913
Ensembl chr18:54,473,444...54,490,814
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA] |
CTD |
PMID:21220312 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Ces1d |
carboxylesterase 1D |
increases expression decreases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of CES1 mRNA Butylated Hydroxyanisole results in decreased expression of CES1D protein |
CTD |
PMID:18227147 PMID:26179144 |
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NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Ces2c |
carboxylesterase 2C |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of CES2C protein |
CTD |
PMID:26179144 |
|
NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
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G |
Ces2e |
carboxylesterase 2E |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of CES2E mRNA |
CTD |
PMID:26179144 |
|
NCBI chr19:157,447...172,822
Ensembl chr19:157,407...172,856
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
ISO |
CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A1 mRNA]; CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:25174530 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
decreases activity |
EXP |
Butylated Hydroxyanisole results in decreased activity of CYP17A1 protein |
CTD |
PMID:27388148 |
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NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO |
Butylated Hydroxyanisole results in increased expression of CYP1A1 mRNA CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:25174530 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases expression multiple interactions |
ISO |
Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:25174530 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of CYP2B10 mRNA |
CTD |
PMID:17627975 |
|
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2j4 |
cytochrome P450, family 2, subfamily j, polypeptide 4 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of CYP2J2 mRNA |
CTD |
PMID:24021950 |
|
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]] |
CTD |
PMID:18691550 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Dmp1 |
dentin matrix acidic phosphoprotein 1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of DMP1 mRNA |
CTD |
PMID:19000923 |
|
NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
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G |
Dusp1 |
dual specificity phosphatase 1 |
affects response to substance multiple interactions |
ISO |
DUSP1 protein affects the susceptibility to Butylated Hydroxyanisole DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]] |
CTD |
PMID:30844440 |
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NCBI chr10:16,680,478...16,683,275
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein] Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of EGFR protein]; Butylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of EGFR protein] |
CTD |
PMID:17028263 PMID:21220312 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Ephx1 |
epoxide hydrolase 1 |
increases activity |
ISO |
Butylated Hydroxyanisole results in increased activity of EPHX1 protein |
CTD |
PMID:3621371 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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G |
Ephx2 |
epoxide hydrolase 2 |
decreases expression increases activity |
ISO |
Butylated Hydroxyanisole results in decreased expression of EPHX2 protein Butylated Hydroxyanisole results in increased activity of EPHX2 protein |
CTD |
PMID:3621371 |
|
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Esr1 |
estrogen receptor 1 |
affects binding increases activity decreases expression multiple interactions |
ISO |
Butylated Hydroxyanisole binds to ESR1 protein Butylated Hydroxyanisole results in increased activity of ESR1 protein Butylated Hydroxyanisole results in decreased expression of ESR1 mRNA Butylated Hydroxyanisole inhibits the reaction [Estradiol binds to ESR1 protein] |
CTD |
PMID:12822488 PMID:14579009 PMID:16756374 PMID:19063592 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
affects binding increases activity multiple interactions |
ISO |
Butylated Hydroxyanisole binds to ESR2 protein Butylated Hydroxyanisole results in increased activity of ESR2 protein Butylated Hydroxyanisole inhibits the reaction [Estradiol binds to ESR2 protein] |
CTD |
PMID:12822488 PMID:16756374 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Butylated Hydroxyanisole promotes the reaction [FOS protein binds to NQO1 promoter] |
CTD |
PMID:8375015 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of FOSL1 mRNA |
CTD |
PMID:19000923 |
|
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Fth1 |
ferritin heavy chain 1 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of FTH1 protein |
CTD |
PMID:38657941 |
|
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of GCLC mRNA Butylated Hydroxyanisole results in increased expression of GCLC mRNA; Butylated Hydroxyanisole results in increased expression of GCLC protein |
CTD |
PMID:16426233 PMID:25922074 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of GPX4 protein |
CTD |
PMID:38657941 |
|
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gsta2 |
glutathione S-transferase alpha 2 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of GSTA2 mRNA; Butylated Hydroxyanisole results in increased expression of GSTA2 protein |
CTD |
PMID:1859377 PMID:2049074 PMID:11309284 PMID:11991805 PMID:16426233 |
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NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
increases expression |
EXP |
Butylated Hydroxyanisole results in increased expression of GSTA3 protein |
CTD |
PMID:9794803 |
|
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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G |
Gsta5 |
glutathione S-transferase alpha 5 |
multiple interactions increases expression |
EXP ISO |
Butylated Hydroxyanisole promotes the reaction [GSTA5 protein affects the metabolism of aflatoxin B1-2,3-oxide]; Butylated Hydroxyanisole results in increased expression of and results in increased activity of GSTA5 protein Butylated Hydroxyanisole results in increased expression of GSTA5 protein Butylated Hydroxyanisole results in increased expression of GSTA1 mRNA; Butylated Hydroxyanisole results in increased expression of GSTA1 protein |
CTD |
PMID:1859377 PMID:2049074 PMID:2597111 PMID:8198522 PMID:9794803 PMID:11309284 PMID:11991805 PMID:16426233 PMID:29086419 More...
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NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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G |
Gstm1 |
glutathione S-transferase mu 1 |
multiple interactions increases activity increases expression |
ISO |
NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTM1 protein] Butylated Hydroxyanisole results in increased expression of GSTM1 mRNA; Butylated Hydroxyanisole results in increased expression of GSTM1 protein; Butylated Hydroxyanisole results in increased expression of GSTM5 protein |
CTD |
PMID:2597111 PMID:11309284 PMID:11895860 PMID:11991805 PMID:18723825 PMID:29086419 More...
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
Gstm2 |
glutathione S-transferase mu 2 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of GSTM2 mRNA; Butylated Hydroxyanisole results in increased expression of GSTM2 protein |
CTD |
PMID:1859377 PMID:11991805 PMID:18723825 |
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NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gstm4 |
glutathione S-transferase mu 4 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of GSTM4 mRNA; Butylated Hydroxyanisole results in increased expression of GSTM4 protein |
CTD |
PMID:1859377 PMID:11991805 PMID:18723825 |
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NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
increases expression |
ISO EXP |
Butylated Hydroxyanisole results in increased expression of GSTM3 mRNA; Butylated Hydroxyanisole results in increased expression of GSTM3 protein |
CTD |
PMID:6822548 PMID:9794803 PMID:11991805 PMID:18723825 |
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NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
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G |
Gsto1 |
glutathione S-transferase omega 1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of GSTO1 mRNA |
CTD |
PMID:18723825 |
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NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
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G |
Gstp1 |
glutathione S-transferase pi 1 |
increases activity increases expression multiple interactions |
ISO EXP |
Butylated Hydroxyanisole results in increased activity of GSTP1 protein Butylated Hydroxyanisole results in increased expression of GSTP1 protein NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTP1 protein]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased expression of GSTP1 protein] |
CTD |
PMID:2597111 PMID:9794803 PMID:11895860 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
increases expression |
EXP |
Butylated Hydroxyanisole results in increased expression of GSTT1 mRNA; Butylated Hydroxyanisole results in increased expression of GSTT1 protein |
CTD |
PMID:9794803 |
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NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Has2 |
hyaluronan synthase 2 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA] |
CTD |
PMID:21220312 |
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NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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G |
Hells |
helicase, lymphoid specific |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of HELLS mRNA |
CTD |
PMID:19000923 |
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NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
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G |
Hexb |
hexosaminidase subunit beta |
multiple interactions |
EXP |
zinc chloride inhibits the reaction [Butylated Hydroxyanisole results in increased secretion of HEXB protein] |
CTD |
PMID:15272608 |
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NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
1-aminobenzotriazole inhibits the reaction [[Butylated Hydroxyanisole co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; [Hydrogen Peroxide co-treated with Butylated Hydroxyanisole] results in increased expression of HMOX1 mRNA; Buthionine Sulfoximine promotes the reaction [Butylated Hydroxyanisole results in increased expression of HMOX1 mRNA] Butylated Hydroxyanisole results in increased expression of HMOX1 mRNA; Butylated Hydroxyanisole results in increased expression of HMOX1 protein |
CTD |
PMID:18227147 PMID:25922074 PMID:29086419 PMID:29486183 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hoxa1 |
homeobox A1 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of HOXA1 mRNA |
CTD |
PMID:28927898 |
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NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Hoxb9 |
homeo box B9 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of HOXB9 mRNA |
CTD |
PMID:28927898 |
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NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
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G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
decreases expression |
EXP |
Butylated Hydroxyanisole results in decreased expression of HSD17B3 mRNA; Butylated Hydroxyanisole results in decreased expression of HSD17B3 protein |
CTD |
PMID:27388148 |
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NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
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G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases activity |
EXP |
Butylated Hydroxyanisole results in decreased activity of HSD3B1 protein |
CTD |
PMID:27388148 |
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NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO EXP |
Butylated Hydroxyanisole results in decreased expression of and results in decreased secretion of IFNG protein [Food Preservatives results in increased abundance of Butylated Hydroxyanisole] which results in increased expression of IFNG mRNA |
CTD |
PMID:22250088 PMID:32179172 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]; Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]; Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]] |
CTD |
PMID:18691550 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Il10 |
interleukin 10 |
multiple interactions |
EXP |
[Food Preservatives results in increased abundance of Butylated Hydroxyanisole] which results in increased expression of IL10 mRNA |
CTD |
PMID:32179172 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]] |
CTD |
PMID:18691550 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO EXP |
Butylated Hydroxyanisole inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] Butylated Hydroxyanisole inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone] [Food Preservatives results in increased abundance of Butylated Hydroxyanisole] which results in increased expression of IL1B mRNA |
CTD |
PMID:1515551 PMID:8186192 PMID:32179172 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of IL1RL1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO EXP |
Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]; Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]]; Butylated Hydroxyanisole inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]] [Food Preservatives results in increased abundance of Butylated Hydroxyanisole] which results in increased expression of IL6 mRNA |
CTD |
PMID:8186192 PMID:18691550 PMID:30844440 PMID:32179172 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Butylated Hydroxyanisole results in increased expression of JUN mRNA Butylated Hydroxyanisole promotes the reaction [JUN protein binds to NQO1 promoter] |
CTD |
PMID:8375015 PMID:19000923 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Lfng |
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of LFNG mRNA |
CTD |
PMID:28927898 |
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NCBI chr12:14,030,551...14,038,996
Ensembl chr12:14,018,333...14,039,008
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of PGR mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:21220312 |
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NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
increases expression |
EXP |
Butylated Hydroxyanisole results in increased expression of LHCGR mRNA |
CTD |
PMID:27388148 |
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NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G |
Lhx1 |
LIM homeobox 1 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of LHX1 mRNA |
CTD |
PMID:28927898 |
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NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAP2K4 protein] |
CTD |
PMID:16407847 |
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NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [ellipticine results in increased phosphorylation of MAPK1 protein]; Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK1 protein] Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:16407847 PMID:21220312 PMID:21843585 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]] |
CTD |
PMID:18691550 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [ellipticine results in increased phosphorylation of MAPK3 protein]; Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK3 protein] Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:16407847 PMID:21220312 PMID:21843585 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO EXP |
Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK8 protein] Butylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]; Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]; Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]; Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein] |
CTD |
PMID:15989949 PMID:16407847 PMID:18593901 PMID:18691550 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Meox1 |
mesenchyme homeobox 1 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of MEOX1 mRNA |
CTD |
PMID:28927898 |
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NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
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G |
Mgst3 |
microsomal glutathione S-transferase 3 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of MGST3 mRNA |
CTD |
PMID:18723825 |
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NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
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G |
Mixl1 |
Mix paired-like homeobox 1 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of MIXL1 mRNA |
CTD |
PMID:28927898 |
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NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065
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G |
Mki67 |
marker of proliferation Ki-67 |
increases expression decreases expression |
EXP |
Butylated Hydroxyanisole results in increased expression of MKI67 protein Butylated Hydroxyanisole results in decreased expression of MKI67 protein |
CTD |
PMID:23535288 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of COX2 protein] Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of COX2 protein] |
CTD |
PMID:12470298 |
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NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
affects activity multiple interactions increases expression affects response to substance |
ISO EXP |
Butylated Hydroxyanisole affects the activity of NFE2L2 protein [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA; [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA; [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNA; [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC5 mRNA; [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC6 mRNA; Butylated Hydroxyanisole binds to and results in increased activity of NFE2L2 protein; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTM1 protein]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTP1 protein]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased expression of GSTP1 protein] Butylated Hydroxyanisole inhibits the reaction [Estradiol inhibits the reaction [NFE2L2 protein binds to SOD3 promoter]] Butylated Hydroxyanisole results in increased expression of NFE2L2 protein Butylated Hydroxyanisole results in increased stability of and results in increased expression of NFE2L2 protein NFE2L2 protein affects the susceptibility to Butylated Hydroxyanisole |
CTD |
PMID:11309284 PMID:11895860 PMID:15833929 PMID:15919853 PMID:22530035 PMID:23027624 PMID:30844440 More...
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases activity increases expression multiple interactions |
ISO EXP |
Butylated Hydroxyanisole results in increased activity of NQO1 protein Butylated Hydroxyanisole results in increased expression of NQO1 mRNA Butylated Hydroxyanisole results in increased expression of NQO1 mRNA; Butylated Hydroxyanisole results in increased expression of NQO1 protein Butylated Hydroxyanisole promotes the reaction [FOS protein binds to NQO1 promoter]; Butylated Hydroxyanisole promotes the reaction [JUN protein binds to NQO1 promoter] |
CTD |
PMID:8375015 PMID:10092053 PMID:11309284 PMID:15919853 PMID:16045903 PMID:16403784 PMID:17627975 PMID:18227147 PMID:19144771 PMID:25922074 PMID:29086419 More...
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of NR1I2 mRNA |
CTD |
PMID:17627975 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of NR1I3 mRNA |
CTD |
PMID:17627975 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein] |
CTD |
PMID:16407847 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pgr |
progesterone receptor |
affects binding multiple interactions increases expression |
ISO |
Butylated Hydroxyanisole binds to PGR protein Butylated Hydroxyanisole inhibits the reaction [Progesterone binds to PGR protein] Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of PGR mRNA] Butylated Hydroxyanisole results in increased expression of PGR mRNA |
CTD |
PMID:12822488 PMID:14579009 PMID:21220312 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Phex |
phosphate regulating endopeptidase X-linked |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of PHEX mRNA |
CTD |
PMID:19000923 |
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NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469
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G |
Pik3r5 |
phosphoinositide-3-kinase, regulatory subunit 5 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of PIK3R5 mRNA |
CTD |
PMID:19000923 |
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NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
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G |
Prkcd |
protein kinase C, delta |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [Ursodeoxycholic Acid results in increased localization of PRKCD protein] |
CTD |
PMID:21362627 |
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NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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G |
Psmc6 |
proteasome 26S subunit, ATPase 6 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of PSMC6 mRNA] Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of PSMC6 mRNA] |
CTD |
PMID:12470298 |
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NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]] |
CTD |
PMID:21220312 PMID:30844440 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rad51ap1 |
RAD51 associated protein 1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of RAD51AP1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524
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G |
Sesn2 |
sestrin 2 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [erastin results in increased expression of SESN2 protein] |
CTD |
PMID:31323261 |
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NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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G |
Slc2a1 |
solute carrier family 2 member 1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of SLC2A1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc3a2 |
solute carrier family 3 member 2 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of SLC3A2 protein |
CTD |
PMID:38657941 |
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NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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G |
Slc7a11 |
solute carrier family 7 member 11 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of SLC7A11 protein |
CTD |
PMID:38657941 |
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NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Slco2b1 |
solute carrier organic anion transporter family, member 2b1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of SLCO2B1 mRNA |
CTD |
PMID:15919853 |
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NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
[Butylated Hydroxyanisole co-treated with Butylated Hydroxytoluene] results in decreased expression of SOD2 mRNA; Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in decreased activity of SOD2 protein] |
CTD |
PMID:14981915 PMID:36007723 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sod3 |
superoxide dismutase 3 |
multiple interactions increases expression increases activity |
EXP |
Butylated Hydroxyanisole inhibits the reaction [Estradiol inhibits the reaction [NFE2L2 protein binds to SOD3 promoter]]; Butylated Hydroxyanisole inhibits the reaction [Estradiol results in decreased activity of SOD3 protein]; Butylated Hydroxyanisole inhibits the reaction [Estradiol results in decreased expression of SOD3 mRNA]; Butylated Hydroxyanisole inhibits the reaction [Estradiol results in decreased expression of SOD3 protein] Butylated Hydroxyanisole results in increased expression of SOD3 mRNA; Butylated Hydroxyanisole results in increased expression of SOD3 protein Butylated Hydroxyanisole results in increased activity of SOD3 protein |
CTD |
PMID:23027624 |
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NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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G |
Sp5 |
Sp5 transcription factor |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of SP5 mRNA |
CTD |
PMID:28927898 |
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NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733
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G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
decreases expression |
EXP |
Butylated Hydroxyanisole results in decreased expression of SRD5A1 mRNA; Butylated Hydroxyanisole results in decreased expression of SRD5A1 protein |
CTD |
PMID:27388148 |
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NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of SRXN1 protein |
CTD |
PMID:27358234 |
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NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]; Butylated Hydroxyanisole inhibits the reaction [Vanadates results in increased phosphorylation of STAT3 protein]; Butylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:17028263 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Sult1e1 |
sulfotransferase family 1E member 1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of SULT1E1 mRNA |
CTD |
PMID:25922074 |
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NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
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G |
Tbx6 |
T-box transcription factor 6 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of TBX6 mRNA |
CTD |
PMID:28927898 |
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NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593
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G |
Tbxt |
T-box transcription factor T |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of T mRNA |
CTD |
PMID:28927898 |
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NCBI chr 1:52,298,104...52,309,813
Ensembl chr 1:52,298,099...52,305,864
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G |
Tfeb |
transcription factor EB |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of TFEB protein |
CTD |
PMID:38657941 |
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NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
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G |
Tnf |
tumor necrosis factor |
multiple interactions affects response to substance decreases response to substance |
ISO EXP |
Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of ATP6V1A protein]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of COX2 protein]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of PSMC6 mRNA]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Dinoprostone]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased secretion of Arachidonic Acid] Butylated Hydroxyanisole affects the susceptibility to TNF protein Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]; Butylated Hydroxyanisole inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]] Butylated Hydroxyanisole results in decreased susceptibility to TNF protein [Food Preservatives results in increased abundance of Butylated Hydroxyanisole] which results in increased expression of TNF mRNA |
CTD |
PMID:1515551 PMID:8186192 PMID:8740460 PMID:10588948 PMID:12470298 PMID:30844440 PMID:32179172 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip6 |
TNF alpha induced protein 6 |
multiple interactions |
ISO |
Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA] |
CTD |
PMID:21220312 |
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NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions |
ISO |
TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]] |
CTD |
PMID:10588948 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
EXP ISO |
Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TP53 protein] Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein] |
CTD |
PMID:18593901 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of UGT1A1 mRNA |
CTD |
PMID:18227147 PMID:19144771 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of UGT1A6 mRNA |
CTD |
PMID:19144771 |
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NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt2b1 |
UDP glucuronosyltransferase 2 family, polypeptide B1 |
decreases expression |
ISO |
Butylated Hydroxyanisole results in decreased expression of UGT2B1 mRNA |
CTD |
PMID:19144771 |
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NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO |
Butylated Hydroxyanisole results in increased expression of VEGFA mRNA |
CTD |
PMID:19000923 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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