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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-acetylaminofluorene
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Accession:CHEBI:76343 term browser browse the term
Definition:A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is replaced by a 9H-fluoren-4-yl group.
Synonyms:exact_synonym: N-(9H-fluoren-4-yl)acetamide
 related_synonym: 4-AAF;   4-Acetylaminofluoren;   4-fluorenylacetamide;   4AAF;   Formula=C15H13NO;   InChI=1S/C15H13NO/c1-10(17)16-14-8-4-6-12-9-11-5-2-3-7-13(11)15(12)14/h2-8H,9H2,1H3,(H,16,17);   InChIKey=PHPWISAFHNEMSR-UHFFFAOYSA-N;   N-4-fluorenylacetamide;   N-9H-fluoren-4-ylacetamide;   N-fluoren-4-ylacetamide;   SMILES=C=12C3=C(CC1C=CC=C2NC(=O)C)C=CC=C3
 xref: CAS:28322-02-3
 xref_mesh: MESH:C028676
 xref: PMID:2366818;   PMID:2417700;   PMID:3785275;   PMID:7508825;   Reaxys:2975269


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4-acetylaminofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP 4-acetylaminofluorene results in increased expression of ABCB1B mRNA CTD PMID:17070881 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases expression EXP 4-acetylaminofluorene results in increased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP 4-acetylaminofluorene results in increased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Aen apoptosis enhancing nuclease decreases expression EXP 4-acetylaminofluorene results in decreased expression of AEN mRNA CTD PMID:17070881 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 4-acetylaminofluorene results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 4-acetylaminofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP 4-acetylaminofluorene results in increased expression of ALDH1A4 mRNA CTD PMID:17070881 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 4-acetylaminofluorene results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 4-acetylaminofluorene results in increased expression of BAX mRNA CTD PMID:17070881 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of BTG2 mRNA CTD PMID:17070881 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C7 complement C7 decreases expression EXP 4-acetylaminofluorene results in decreased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535 		JBrowse link
G Cblc Cbl proto-oncogene C increases expression EXP 4-acetylaminofluorene results in increased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755 		JBrowse link
G Ccng1 cyclin G1 increases expression EXP 4-acetylaminofluorene results in increased expression of CCNG1 mRNA CTD PMID:17070881 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd276 Cd276 molecule increases expression EXP 4-acetylaminofluorene results in increased expression of CD276 mRNA CTD PMID:17070881 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP 4-acetylaminofluorene results in decreased expression of CDKN1A mRNA CTD PMID:17070881 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 4-acetylaminofluorene results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546 		JBrowse link
G Cryab crystallin, alpha B decreases expression EXP 4-acetylaminofluorene results in decreased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP 4-acetylaminofluorene results in decreased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191 		JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 4-acetylaminofluorene results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression EXP 4-acetylaminofluorene results in decreased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP 4-acetylaminofluorene results in increased expression of EPCAM mRNA CTD PMID:17070881 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 4-acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Fas Fas cell surface death receptor increases expression
decreases expression		 EXP 4-acetylaminofluorene results in increased expression of FAS mRNA
4-acetylaminofluorene results in decreased expression of FAS mRNA		 CTD PMID:17070881 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression EXP 4-acetylaminofluorene results in decreased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of GRIA3 mRNA CTD PMID:17070881 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 4-acetylaminofluorene results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 increases expression EXP 4-acetylaminofluorene results in increased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression EXP 4-acetylaminofluorene results in increased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 4-acetylaminofluorene results in increased expression of MGMT mRNA CTD PMID:17070881 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP 4-acetylaminofluorene results in increased expression of NUPR1 mRNA CTD PMID:17070881 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP 4-acetylaminofluorene results in increased expression of POR mRNA CTD PMID:15089088 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 4-acetylaminofluorene results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651 		JBrowse link
G Serpina7 serpin family A member 7 decreases expression EXP 4-acetylaminofluorene results in decreased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040 		JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP 4-acetylaminofluorene results in increased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP 4-acetylaminofluorene results in increased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase increases expression EXP 4-acetylaminofluorene results in increased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376 		JBrowse link
G Sulf2 sulfatase 2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of SULF2 mRNA CTD PMID:17070881 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP 4-acetylaminofluorene results in increased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:75,451,178...75,508,142
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP 4-acetylaminofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15089088 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958 		JBrowse link
G Zmat3 zinc finger, matrin type 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of ZMAT3 mRNA CTD PMID:17070881 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        mitogen 3482
          4-acetylaminofluorene 44
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      carboxylic acid 18569
                                        carboacyl group 17687
                                          univalent carboacyl group 17687
                                            carbamoyl group 17531
                                              carboxamide 17531
                                                acetamides 14648
                                                  4-acetylaminofluorene 44
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