The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
[RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased chemical synthesis of Oxygen]; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased phosphorylation of and results in increased activity of NOS3 protein]; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK1 protein]; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK3 protein]
[afimoxifene binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Equol; [fulvestrant binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Equol; Equol binds to and results in increased activity of ESR1 protein; Estradiol affects the reaction [Equol affects the activity of ESR1 protein] Equol results in increased expression of ESR1 mRNA; Equol results in increased expression of ESR1 mRNA alternative form Equol results in increased activity of ESR1 protein Equol binds to ESR1 protein
Equol binds to and results in increased activity of ESR2 protein; Equol inhibits the reaction [KAT5 protein results in decreased activity of ESR2 protein]; Equol inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]; Estradiol affects the reaction [Equol affects the activity of ESR2 protein] Equol results in increased activity of ESR2 protein Equol binds to ESR2 protein
Equol inhibits the reaction [KAT5 protein results in decreased activity of ESR2 protein]; Equol inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]
[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK1 protein]; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK1 protein]; [U 0126 results in decreased phosphorylation of [MAPK1 protein co-treated with MAPK3 protein]] which results in decreased susceptibility to Equol; AG 1879 inhibits the reaction [Equol results in increased phosphorylation of MAPK1 protein]; Equol results in increased activity of and results in increased phosphorylation of MAPK1 protein; Pertussis Toxin inhibits the reaction [Equol results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Equol results in increased activity of and results in increased phosphorylation of MAPK1 protein]
[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK3 protein]; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK3 protein]; [U 0126 results in decreased phosphorylation of [MAPK1 protein co-treated with MAPK3 protein]] which results in decreased susceptibility to Equol; AG 1879 inhibits the reaction [Equol results in increased phosphorylation of MAPK3 protein]; Equol results in increased activity of and results in increased phosphorylation of MAPK3 protein; Pertussis Toxin inhibits the reaction [Equol results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Equol results in increased activity of and results in increased phosphorylation of MAPK3 protein]
[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased activity of and results in increased phosphorylation of NOS3 protein]; [Equol results in increased chemical synthesis of Superoxides] which results in increased activity of and results in increased phosphorylation of NOS3 protein; [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased phosphorylation of and results in increased activity of NOS3 protein]; Equol inhibits the reaction [NOS3 protein binds to CAV1 protein]; Equol results in increased activity of and results in increased phosphorylation of NOS3 protein; Equol results in increased phosphorylation of and results in increased activity of NOS3 protein; Manganese inhibits the reaction [Equol results in increased activity of and results in increased phosphorylation of NOS3 protein]; Pertussis Toxin inhibits the reaction [Equol results in increased activity of and results in increased phosphorylation of NOS3 protein]; Rotenone inhibits the reaction [Equol results in increased phosphorylation of and results in increased activity of NOS3 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Equol results in increased chemical synthesis of Superoxides] which results in increased phosphorylation of NOS3 protein]
Equol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Equol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased activity of and results in increased phosphorylation of NOS3 protein]; [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK1 protein]; [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK3 protein]
[Gemcitabine co-treated with licoricidin] results in decreased phosphorylation of AKT1 protein; [licoricidin co-treated with Gemcitabine] results in decreased phosphorylation of AKT1 protein licoricidin results in decreased phosphorylation of AKT1 protein
licoricidin promotes the reaction [Gemcitabine results in increased activity of CASP3 protein]; licoricidin promotes the reaction [Gemcitabine results in increased expression of and results in increased activity of CASP3 protein]; licoricidin results in increased expression of and results in increased activity of CASP3 protein licoricidin results in increased activity of CASP3 protein
licoricidin inhibits the reaction [Gemcitabine results in increased phosphorylation of RELA protein] licoricidin results in decreased phosphorylation of RELA protein