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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sodium sulfide (anhydrous)
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Accession:CHEBI:76208 term browser browse the term
Definition:A sulfide salt with formula Na2S. The pentahydrate and (particularly) the nonahydrate are also known. In gel form, sodium sulfide is used to soften toenails to assist in trimming (and so relive pain) of ingrowing toenails.
Synonyms:related_synonym: Formula=Na2S;   InChI=1S/2Na.S/q2*+1;-2;   InChIKey=GRVFOGOEDUUMBP-UHFFFAOYSA-N;   Na2S;   SMILES=[Na+].[Na+].[S--];   anh. sodium sulfide;   disodium monosulfide;   disodium sulfide;   sodium monosulfide;   sodium sulfuret;   sodium sulphide
 alt_id: CHEBI:76183
 xref: CAS:1313-82-2
 xref_mesh: MESH:C033479
 xref: PMID:12793804;   PMID:14848282;   PMID:19810706;   Reaxys:11323291;   Wikipedia:Sodium_sulfide


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sodium sulfide (anhydrous) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions EXP [[sodium sulfide results in increased abundance of Hydrogen Sulfide] which co-treated with Paraquat] results in decreased expression of IDH2 protein; [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of and results in decreased activity of IDH2 protein] CTD PMID:32064027 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Il6 interleukin 6 multiple interactions EXP sodium sulfide inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein] CTD PMID:23624824 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP NFE2L2 protein affects the reaction [[sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein]] CTD PMID:32064027 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Sirt3 sirtuin 3 multiple interactions EXP [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein]; NFE2L2 protein affects the reaction [[sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein]] CTD PMID:32064027 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Sod1 superoxide dismutase 1 increases metabolic processing ISO sodium sulfide results in increased metabolism of SOD1 protein CTD PMID:15096637 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    chemical entity 19875
      molecular entity 19872
        inorganic molecular entity 19536
          inorganic salt 11775
            inorganic sodium salt 8221
              sodium sulfide (anhydrous) 5
                sodium sulfide nonahydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    main group molecular entity 19763
                      s-block molecular entity 19511
                        alkali metal molecular entity 10635
                          sodium molecular entity 8646
                            elemental sodium 8646
                              sodium(1+) 8646
                                sodium salt 8646
                                  inorganic sodium salt 8221
                                    sodium sulfide (anhydrous) 5
                                      sodium sulfide nonahydrate 0
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