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Accession:CHEBI:76163 term browser browse the term
Definition:A monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Stevens-Johnson syndrome.
Synonyms:exact_synonym: 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
 related_synonym: 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide;   4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide;   BRN 0577221;   EINECS 252-084-5;   Formula=C14H13N3O5S;   InChI=1S/C14H13N3O5S/c1-8-7-11(16-22-8)15-14(19)12-13(18)9-5-3-4-6-10(9)23(20,21)17(12)2/h3-7,18H,1-2H3,(H,15,16,19);   InChIKey=YYUAYBYLJSNDCX-UHFFFAOYSA-N;   Maxicam;   N-(5-methyl-3-isoxazolyl)-4-hydroxy-2-methyl-2H-1,2-benzthiazine-3-carboxamide 1,1-dioxide;   SMILES=CN1C(C(=O)Nc2cc(C)on2)=C(O)c2ccccc2S1(=O)=O;   UNII-8XU734C4NG;   W 8495;   isoxicamo;   isoxicamum
 xref: CAS:34552-84-6 "ChemIDplus";   CAS:34552-84-6 "KEGG DRUG";   Drug_Central:1509 "DrugCentral";   KEGG:D04639;   PMID:1236641 "Europe PMC";   PMID:1499594 "Europe PMC";   PMID:24061247 "Europe PMC";   PMID:2575504 "Europe PMC";   PMID:2618088 "Europe PMC";   PMID:3436154 "Europe PMC";   PMID:3557542 "Europe PMC";   PMID:3620270 "Europe PMC";   PMID:3620275 "Europe PMC";   PMID:3620277 "Europe PMC";   PMID:3904436 "Europe PMC";   PMID:3904438 "Europe PMC";   PMID:6391795 "Europe PMC";   Patent:DE2208351;   Patent:US3787324;   Reaxys:577221 "Reaxys"

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Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        anti-inflammatory agent 14907
          anti-inflammatory drug 13590
            non-steroidal anti-inflammatory drug 12666
              isoxicam 0
Path 2
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  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                monocarboxylic acid amide 13180
                                                  isoxicam 0
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