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Accession:CHEBI:76016 term browser browse the term
Definition:An N-arylpiperazine in which the aryl group is specified as 2-[(2,4-dimethylphenyl)sulfanyl]phenyl. Used (as its hydrobromide salt) for treatment of major depressive disorder.
Synonyms:exact_synonym: 1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine
 related_synonym: Formula=C18H22N2S;   Lu AA21004;   vortioxetina;   vortioxetinum
 xref: CAS:508233-74-7 "ChemIDplus";   CAS:508233-74-7 "KEGG DRUG";   Drug_Central:4806 "DrugCentral";   KEGG:D10184
 xref_mesh: MESH:C557874
 xref: PMID:21767441 "Europe PMC";   PMID:22171087 "Europe PMC";   PMID:22209361 "Europe PMC";   PMID:22448783 "Europe PMC";   PMID:22475889 "Europe PMC";   PMID:22495621 "Europe PMC";   PMID:22496396 "Europe PMC";   PMID:22572889 "Europe PMC";   PMID:22612991 "Europe PMC";   PMID:22898365 "Europe PMC";   PMID:22901346 "Europe PMC";   PMID:22901736 "Europe PMC";   PMID:22963932 "Europe PMC";   PMID:22978748 "Europe PMC";   PMID:23089374 "Europe PMC";   PMID:23252878 "Europe PMC";   PMID:23380522 "Europe PMC";   PMID:23428337 "Europe PMC";   PMID:23531115 "Europe PMC";   PMID:23588319 "Europe PMC";   PMID:23721744 "Europe PMC";   PMID:23903233 "Europe PMC";   PMID:23916504 "Europe PMC";   PMID:23975654 "Europe PMC";   PMID:24016840 "Europe PMC";   Patent:WO2008113359;   Reaxys:11341374 "Reaxys";   Wikipedia:Vortioxetine
 cyclic_relationship: is_conjugate_base_of CHEBI:76017

show annotations for term's descendants       view all columns           Sort by:
vortioxetine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6480464
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:6480464
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:6480464
G Htr3a 5-hydroxytryptamine receptor 3A JBrowse link 8 53,211,436 53,223,878 RGD:6480464
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480464
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        pharmacological role 18684
          neurotransmitter agent 16233
            serotonergic drug 3846
              serotonergic agonist 878
                vortioxetine 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8521
                                          N-arylpiperazine 2617
                                            vortioxetine 6
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