The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A furonaphthodioxole that is a synthetic derivative of podophyllotoxin with anti-tumour activity; causes single- and double-stranded breaks in DNA and DNA-protein cross-links and prevents repair by topoisomerase II binding.
[Tretinoin co-treated with Teniposide] results in increased expression of CETP mRNA; CETP protein promotes the reaction [Teniposide results in decreased abundance of Triglycerides]; NR1H2 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; NR1H3 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [CETP protein results in decreased abundance of Cholesterol, HDL]; Teniposide promotes the reaction [CETP protein results in decreased abundance of Cholesterol]; Teniposide promotes the reaction [CETP protein results in decreased abundance of Triglycerides]; Teniposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Teniposide results in increased expression of and results in increased secretion of CETP protein; Tretinoin promotes the reaction [Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]; Tretinoin promotes the reaction [Teniposide results in increased expression of CETP protein]
Cyclosporine inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Dexamethasone inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Erythromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Midazolam inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]
NR1H2 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA] Teniposide affects the localization of NR1H2 protein NR1H2 protein affects the susceptibility to Teniposide
NR1H3 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Teniposide results in increased expression of and affects the localization of NR1H3 protein Teniposide results in increased expression of NR1H3 mRNA NR1H3 protein affects the susceptibility to Teniposide
Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]