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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cytochalasan alkaloid
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Accession:CHEBI:75946 term browser browse the term
Definition:Any alkaloid characterized by the presence of an isoindole nucleus fused to a macrocyclic ring.
Synonyms:related_synonym: cytochalasan alkaloids


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chaetoglobosin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
EXP chaetoglobosins results in increased phosphorylation of AKT1 protein
wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of AKT1 protein]
CTD PMID:18040759 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP chaetoglobosins inhibits the reaction [Dieldrin results in decreased phosphorylation of GJA1 protein]; chaetoglobosins inhibits the reaction [Hexachlorocyclohexane results in decreased phosphorylation of GJA1 protein] CTD PMID:18040759 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions
EXP chaetoglobosins results in increased phosphorylation of GSK3B protein
wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein]
CTD PMID:18040759 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation EXP chaetoglobosins results in increased phosphorylation of MAPK1 protein CTD PMID:18040759 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation EXP chaetoglobosins results in increased phosphorylation of MAPK3 protein CTD PMID:18040759 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases phosphorylation EXP chaetoglobosins results in decreased phosphorylation of RAF1 protein CTD PMID:18040759 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO chaetoglobosins results in increased expression of and results in increased secretion of TNF protein CTD PMID:28535995 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            alkaloid 5349
              cytochalasan alkaloid 7
                19-O-acetylchaetoglobosin A 0
                Cytochalasin E 0
                chaetoglobosin A 7
                chaetoglobosin B 0
                chaetoglobosin C 0
                chaetoglobosin D 0
                chaetoglobosin E 0
                chaetoglobosin F 0
                chaetoglobosin Fex 0
                chaetoglobosin G 0
                chaetoglobosin J 0
                chaetoglobosin Q 0
                chaetoglobosin R 0
                chaetoglobosin T 0
                chaetoglobosin U 0
                chaetoglobosin V 0
                chaetoglobosin Vb 0
                cytochalasin Z16 0
                cytoglobosin A 0
                cytoglobosin B 0
                cytoglobosin C 0
                cytoglobosin D 0
                cytoglobosin E 0
                cytoglobosin F 0
                cytoglobosin G 0
                iso-precytochalasin 0
                isochaetoglobosin D 0
                ketocytochalasin 0
                prochaetoglobosin I 0
                prochaetoglobosin II 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  organic heteropolycyclic compound 17820
                                    organic heterobicyclic compound 16742
                                      benzopyrrole 9339
                                        isoindoles 544
                                          cytochalasin 70
                                            cytochalasan alkaloid 7
                                              19-O-acetylchaetoglobosin A 0
                                              Cytochalasin E 0
                                              chaetoglobosin A 7
                                              chaetoglobosin B 0
                                              chaetoglobosin C 0
                                              chaetoglobosin D 0
                                              chaetoglobosin E 0
                                              chaetoglobosin F 0
                                              chaetoglobosin Fex 0
                                              chaetoglobosin G 0
                                              chaetoglobosin J 0
                                              chaetoglobosin Q 0
                                              chaetoglobosin R 0
                                              chaetoglobosin T 0
                                              chaetoglobosin U 0
                                              chaetoglobosin V 0
                                              chaetoglobosin Vb 0
                                              cytochalasin Z16 0
                                              cytoglobosin A 0
                                              cytoglobosin B 0
                                              cytoglobosin C 0
                                              cytoglobosin D 0
                                              cytoglobosin E 0
                                              cytoglobosin F 0
                                              cytoglobosin G 0
                                              iso-precytochalasin 0
                                              isochaetoglobosin D 0
                                              ketocytochalasin 0
                                              prochaetoglobosin I 0
                                              prochaetoglobosin II 0
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