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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:amfenac
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Accession:CHEBI:75915 term browser browse the term
Definition:An oxo monocarboxylic acid that is benzophenone in which one of the phenyl groups is substituted by an amino group and a carboxymethyl group at position 2 and 3, respectively. The corresponding carboxamide, nepafenac, is a prodrug of amfenac and is used for the treatment of pain and inflammation following cataract surgery.
Synonyms:exact_synonym: (2-amino-3-benzoylphenyl)acetic acid
 related_synonym: (2-Amino-3-benzoylphenyl)essigsaeure;   2-amino-3-benzoylbenzeneacetic acid;   Formula=C15H13NO3;   InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18);   InChIKey=SOYCMDCMZDHQFP-UHFFFAOYSA-N;   SMILES=Nc1c(CC(O)=O)cccc1C(=O)c1ccccc1;   amfenaco;   amfenacum
 xref: CAS:51579-82-9;   Drug_Central:154;   KEGG:D07443;   PMID:10850857;   PMID:19897019;   PMID:3540874;   PMID:8320556;   Patent:DE2324768;   Patent:US4045576;   Reaxys:2381781;   Wikipedia:Amfenac
 cyclic_relationship: is_conjugate_acid_of CHEBI:75917


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Path 1
Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      application 0
        anti-inflammatory agent 0
          anti-inflammatory drug 0
            non-steroidal anti-inflammatory drug 0
              amfenac 0
                bromfenac 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    main group molecular entity 0
                      s-block molecular entity 0
                        hydrogen molecular entity 0
                          hydrides 0
                            inorganic hydride 0
                              pnictogen hydride 0
                                nitrogen hydride 0
                                  azane 0
                                    ammonia 0
                                      organic amino compound 0
                                        aromatic amine 0
                                          anilines 0
                                            substituted aniline 0
                                              amfenac 0
                                                bromfenac 0
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