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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:quercetin 4'-O-beta-D-glucopyranoside
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Accession:CHEBI:75839 term browser browse the term
Definition:A quercetin O-glucoside that is quercetin with a beta-D-glucosyl residue attached at position 4'.
Synonyms:exact_synonym: 2-hydroxy-4-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl beta-D-glucopyranoside
 related_synonym: Formula=C21H20O12;   InChI=1S/C21H20O12/c22-6-13-15(26)17(28)19(30)21(33-13)32-11-2-1-7(3-9(11)24)20-18(29)16(27)14-10(25)4-8(23)5-12(14)31-20/h1-5,13,15,17,19,21-26,28-30H,6H2/t13-,15-,17+,19-,21-/m1/s1;   InChIKey=OIUBYZLTFSLSBY-HMGRVEAOSA-N;   SMILES=OC[C@H]1O[C@@H](Oc2ccc(cc2O)-c2oc3cc(O)cc(O)c3c(=O)c2O)[C@H](O)[C@@H](O)[C@@H]1O;   Spiraein;   Spiraeoside
 xref: CAS:20229-56-5;   HMDB:HMDB0037932
 xref_mesh: MESH:C080613
 xref: PMID:16102260;   PMID:16218662;   PMID:20378972;   PMID:7880864;   PMID:973455;   Patent:KR20100138395;   Reaxys:68011;   Wikipedia:Spiraeoside
 cyclic_relationship: is_conjugate_acid_of CHEBI:187902


show annotations for term's descendants           Sort by:
quercetin 4'-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] CTD PMID:32602595 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 decreases expression ISO spiraeoside results in decreased expression of AP5M1 protein CTD PMID:34116102 NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]]; spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein] CTD PMID:32602595 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]
spiraeoside results in decreased expression of BCL2 protein		 CTD PMID:32602595 PMID:34116102 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO spiraeoside results in decreased expression of BID protein CTD PMID:34116102 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 decreases expression ISO spiraeoside results in decreased expression of CASP3 protein CTD PMID:34116102 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 decreases expression ISO spiraeoside results in decreased expression of CASP9 protein CTD PMID:34116102 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Cat catalase multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein] CTD PMID:32602595 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO spiraeoside results in decreased expression of CDK2 protein CTD PMID:34116102 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cryz crystallin zeta increases activity ISO spiraeoside results in increased activity of CRYZ protein CTD PMID:8968052 NCBI chr 2:246,211,707...246,239,472
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein] CTD PMID:32602595 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Lct lactase multiple interactions EXP [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of spiraeoside CTD PMID:12663055 NCBI chr13:42,334,347...42,376,872
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein] CTD PMID:32602595 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Plcg2 phospholipase C, gamma 2 decreases phosphorylation ISO spiraeoside results in decreased phosphorylation of PLCG2 protein CTD PMID:15613018 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions EXP
ISO		 [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
spiraeoside inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]		 CTD PMID:12663055 PMID:17495124 NCBI chr14:81,778,495...81,843,084
Ensembl chr14:77,553,843...77,618,547 		JBrowse link
G Syk spleen associated tyrosine kinase decreases phosphorylation ISO spiraeoside results in decreased phosphorylation of SYK protein CTD PMID:15613018 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19909
    role 19880
      chemical role 19506
        antioxidant 16196
          quercetin 4'-O-beta-D-glucopyranoside 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 19909
    subatomic particle 19907
      composite particle 19907
        hadron 19907
          baryon 19907
            nucleon 19907
              atomic nucleus 19907
                atom 19907
                  main group element atom 19846
                    p-block element atom 19846
                      carbon group element atom 19784
                        carbon atom 19781
                          organic molecular entity 19781
                            organic molecule 19735
                              organic cyclic compound 19528
                                organic heterocyclic compound 18895
                                  oxacycle 17921
                                    benzopyran 11992
                                      1-benzopyran 11746
                                        flavonoid 7235
                                          anthoxanthin 4588
                                            flavones 4588
                                              hydroxyflavone 4565
                                                flavonols 4432
                                                  7-hydroxyflavonol 4397
                                                    quercetin 4333
                                                      quercetin O-glycoside 471
                                                        quercetin O-glucoside 211
                                                          quercetin 4'-O-beta-D-glucopyranoside 16
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