Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:nitrendipine
go back to main search page
Accession:CHEBI:7582 term browser browse the term
Definition:A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
Synonyms:exact_synonym: ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
 related_synonym: 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester;   BAY e 5009;   Bayotensin;   Baypress;   Bylotensin;   Deiten;   Formula=C18H20N2O6;   InChI=1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3;   InChIKey=PVHUJELLJLJGLN-UHFFFAOYSA-N;   Nidrel;   SMILES=CCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC;   nitrendipino;   nitrendipinum
 xref: CAS:39562-70-4 "KEGG COMPOUND";   CAS:39562-70-4 "NIST Chemistry WebBook";   DrugBank:DB01054;   Drug_Central:1947 "DrugCentral";   HMDB:HMDB0015187;   KEGG:C07713;   KEGG:D00629;   LINCS:LSM-1246
 xref_mesh: MESH:D009568
 xref: PMID:1725797 "Europe PMC";   PMID:1790544 "Europe PMC";   PMID:20398559 "Europe PMC";   PMID:21811924 "Europe PMC";   PMID:23648675 "Europe PMC";   PMID:6085389 "Europe PMC";   Patent:CN101416954;   Patent:DE2117571;   Patent:US3799934;   Reaxys:498823 "Reaxys";   Wikipedia:Nitrendipine


show annotations for term's descendants       view all columns           Sort by:
 
nitrendipine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Cck cholecystokinin JBrowse link 8 130,120,525 130,127,515 RGD:6480464
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 JBrowse link 5 119,546,458 119,564,843 RGD:6480464
G Gast gastrin JBrowse link 10 88,245,532 88,248,485 RGD:6480464
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      application 19246
        fuel 10305
          methanol 2948
            methyl ester 2939
              nitrendipine 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      chalcogen 19242
                        oxygen atom 19196
                          oxygen molecular entity 19196
                            hydroxides 18973
                              organic hydroxy compound 18516
                                alcohol 14919
                                  primary alcohol 13792
                                    ethanols 8042
                                      ethanol 8042
                                        ethyl ester 3049
                                          nitrendipine 14
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.