Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:genkwanin
go back to main search page
Accession:CHEBI:75718 term browser browse the term
Definition:A monomethoxyflavone that is apigenin in which the hydroxy group at position 7 is methylated.
Synonyms:exact_synonym: 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one
 related_synonym: 5,4'-Dihydroxy-7-methoxyflavone;   7-methylapigenin;   Apigenin 7-methyl ether;   Formula=C16H12O5;   InChI=1S/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3;   InChIKey=JPMYFOBNRRGFNO-UHFFFAOYSA-N;   SMILES=COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)cc1
 alt_id: CHEBI:5305
 xref: CAS:437-64-9;   KEGG:C10046;   KNApSAcK:C00001043;   LIPID_MAPS_instance:LMPK12111018
 xref_mesh: MESH:C014568
 xref: PMID:22379361;   PMID:23831487;   PMID:24059652;   Reaxys:292549;   Wikipedia:Genkwanin


show annotations for term's descendants           Sort by:
 
genkwanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases metabolic processing
decreases activity
ISO CYP1A1 protein results in increased metabolism of genkwanin
genkwanin results in decreased activity of CYP1A1 protein
CTD PMID:19666078 PMID:21482471 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing ISO CYP1A2 protein results in increased metabolism of genkwanin CTD PMID:19666078 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases metabolic processing
multiple interactions
ISO CYP1B1 protein results in increased metabolism of genkwanin
[CYP1B1 protein results in increased metabolism of genkwanin] which results in increased chemical synthesis of Apigenin
CTD PMID:19666078 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        biochemical role 19381
          metabolite 19356
            genkwanin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic molecule 19560
                              organic cyclic compound 19351
                                organic heterocyclic compound 18582
                                  oxacycle 17586
                                    benzopyran 10410
                                      1-benzopyran 10136
                                        flavonoid 6516
                                          flavones 4204
                                            hydroxyflavone 4192
                                              trihydroxyflavone 352
                                                apigenin 242
                                                  genkwanin 3
paths to the root