The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A beta-diketone that is acetylacetone (acac) in which both methyl groups have been replaced by phenyl groups. It is a minor constituent of the root extract of licorice (Glycyrrhiza glabra) and exhibits antimutagenic and anticancer effects.
dibenzoylmethane results in decreased phosphorylation of AKT1 protein [dibenzoylmethane co-treated with sulforaphane] results in decreased phosphorylation of AKT1 protein
dibenzoylmethane inhibits the reaction [ESR1 protein binds to BCL2 enhancer]; dibenzoylmethane inhibits the reaction [Estradiol results in increased expression of BCL2 mRNA]
dibenzoylmethane results in increased expression of CBR3 mRNA [sulforaphane co-treated with dibenzoylmethane] results in increased expression of CBR3 mRNA
dibenzoylmethane results in decreased expression of CLU mRNA [sulforaphane co-treated with dibenzoylmethane] results in decreased expression of CLU mRNA
dibenzoylmethane results in increased activity of EPHX1 protein dibenzoylmethane results in increased expression of EPHX1 mRNA [sulforaphane co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA
dibenzoylmethane inhibits the reaction [ESR1 protein binds to BCL2 enhancer]; dibenzoylmethane inhibits the reaction [ESR1 protein binds to MYC enhancer]; dibenzoylmethane inhibits the reaction [ESR1 protein binds to TERT enhancer]
dibenzoylmethane results in increased expression of GCLC mRNA [sulforaphane co-treated with dibenzoylmethane] results in increased expression of GCLC mRNA
dibenzoylmethane results in increased expression of GSTM1 mRNA [sulforaphane co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNA
[sulforaphane co-treated with dibenzoylmethane] results in increased expression of GSTM3 mRNA dibenzoylmethane results in increased expression of GSTM3 mRNA
ODC1 protein inhibits the reaction [dibenzoylmethane results in increased abundance of Reactive Oxygen Species]; ODC1 protein inhibits the reaction [dibenzoylmethane results in increased activity of CASP9 protein]; ODC1 protein inhibits the reaction [dibenzoylmethane results in increased expression of BAD protein] ODC1 protein results in decreased susceptibility to dibenzoylmethane
dibenzoylmethane inhibits the reaction [ESR1 protein binds to TERT enhancer]; dibenzoylmethane inhibits the reaction [Estradiol results in increased expression of TERT mRNA]