The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A pyrazoloquinoline that is (4aR,8aR)-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrazolo[3,4-g]quinoline substituted by a propyl group at position 5. It acts as a dopamine agonist.
Quinpirole results in increased expression of ABCB1 protein Clozapine inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]; Spiperone inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]
Clozapine inhibits the reaction [Quinpirole results in increased activity of ABCB1B promoter]; eticlopride inhibits the reaction [Quinpirole results in increased activity of ABCB1B promoter]; Spiperone inhibits the reaction [Quinpirole results in increased activity of ABCB1B promoter] Quinpirole results in increased expression of ABCB1B mRNA
ADCY5 protein results in increased susceptibility to [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with Quinpirole]; ADCY5 protein results in increased susceptibility to [Colforsin co-treated with Quinpirole]; ADCY5 protein results in increased susceptibility to [dihydrexidine co-treated with Quinpirole]; ADCY5 protein results in increased susceptibility to [Quinpirole co-treated with VIP protein]
[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; [Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Quinpirole co-treated with DRD2 protein alternative form] results in increased activity of RHOA protein; DRD2 protein promotes the reaction [Quinpirole results in decreased expression of POU5F1 mRNA]; epigallocatechin gallate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; JB-788 inhibits the reaction [Quinpirole binds to and results in increased activity of DRD2 protein]; Quinpirole binds to and results in increased activity of DRD2 protein; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium] DRD2 affects the susceptibility to [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Quinpirole]; DRD2 protein affects the reaction [Quinpirole results in increased phosphorylation of CFL1 protein] DRD2 results in increased susceptibility to Quinpirole DRD2 protein affects the susceptibility to Quinpirole [Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine; cypermethrin inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; decamethrin inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]; estradiol 3-benzoate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Haloperidol inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Mirtazapine inhibits the reaction [Quinpirole binds to DRD2 protein]; Nifedipine inhibits the reaction [DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]]; Quinpirole binds to and results in increased activity of DRD2 protein; tautomycin inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine] DRD2 protein results in increased susceptibility to Quinpirole Quinpirole results in increased activity of DRD2 protein
Quinpirole results in decreased expression of FOS mRNA; Quinpirole results in decreased expression of FOS protein Quinpirole results in increased expression of FOS protein 8-(3-chlorostyryl)caffeine promotes the reaction [Quinpirole inhibits the reaction [Reserpine results in increased expression of FOS protein]]; [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Quinpirole] results in increased expression of FOS protein; [SK&F 81297 co-treated with Quinpirole] results in increased expression of FOS protein; Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of FOS protein]; Quinpirole inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of FOS mRNA]; Quinpirole inhibits the reaction [Reserpine results in increased expression of FOS protein]; Quinpirole promotes the reaction [Reserpine results in increased expression of FOS protein]; Reserpine inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Quinpirole] results in increased expression of FOS protein]; Reserpine promotes the reaction [Quinpirole results in increased expression of FOS protein]
[SK&F 81297 co-treated with Quinpirole] results in increased expression of JUNB protein; Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of JUNB protein]
Quinpirole results in decreased expression of POU5F1 mRNA DRD2 protein promotes the reaction [Quinpirole results in decreased expression of POU5F1 mRNA]
Quinpirole affects the reaction [Serotonin results in decreased phosphorylation of PPP1R1B protein]; Quinpirole affects the reaction [Serotonin results in increased phosphorylation of PPP1R1B protein]
[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine co-treated with Quinpirole] results in increased expression of TAC1 mRNA