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Term:NU 1025
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Accession:CHEBI:75399 term browser browse the term
Definition:A member of the class of quinazolines that is quinazolin-4(1H)-one substituted by a hydroxy group at position 8 and a methyl group at position 2. It has been shown to exhibit inhibitory activity against poly(ADP-ribose) polymerase.
Synonyms:exact_synonym: 8-hydroxy-2-methylquinazolin-4(1H)-one
 related_synonym: Formula=C9H8N2O2;   InChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13);   InChIKey=YJDAOHJWLUNFLX-UHFFFAOYSA-N;   SMILES=Cc1nc(=O)c2cccc(O)c2[nH]1
 xref: CAS:90417-38-2 "ChemIDplus";   DrugBank:DB02690;   LINCS:LSM-4643
 xref_mesh: MESH:C115774
 xref: PMID:10069454 "Europe PMC";   PMID:10914735 "Europe PMC";   PMID:9823965 "Europe PMC";   PMID:9857092 "Europe PMC";   Reaxys:10249307 "Reaxys"

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NU 1025 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:6480464

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  CHEBI ontology 19662
    chemical entity 19660
      molecular entity 19657
        polyatomic entity 19575
          heteroatomic molecular entity 19500
            hydroxides 18964
              organic hydroxy compound 18510
                phenols 17867
                  NU 1025 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic molecule 19337
                              organic cyclic compound 19089
                                organic heterocyclic compound 18164
                                  organic heteropolycyclic compound 17427
                                    organic heterobicyclic compound 15905
                                      quinazolines 443
                                        NU 1025 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.