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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester
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Accession:CHEBI:75391 term browser browse the term
Definition:An organic phosphonate that is the trisacetoxymethylester derivative of naphthalene substituted hydroxymethylphosphonic acid. It has been found to inhibit insulin receptor tyrosine kinase activity and insulin stimulated glucose oxidation.
Synonyms:related_synonym: 3-[(acetyloxy)methoxy]-4-(naphthalen-2-yl)-3-oxido-8-oxo-2,5,7-trioxa-3lambda(5)-phosphanon-1-yl acetate;   Formula=C20H23O10P;   HNMPA-(AM)3;   InChI=1S/C20H23O10P/c1-14(21)25-11-28-20(19-9-8-17-6-4-5-7-18(17)10-19)31(24,29-12-26-15(2)22)30-13-27-16(3)23/h4-10,20H,11-13H2,1-3H3;   InChIKey=UQODAZKXEREJLZ-UHFFFAOYSA-N;   SMILES=CC(=O)OCOC(c1ccc2ccccc2c1)P(=O)(OCOC(C)=O)OCOC(C)=O
 xref: LINCS:LSM-6443
 xref_mesh: MESH:C519736
 xref: PMID:2550060;   Reaxys:11322049



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hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins1 insulin 1 multiple interactions EXP hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester inhibits the reaction [INS1 protein inhibits the reaction [Epinephrine results in increased transport of Fatty Acids, Nonesterified]] CTD PMID:15172182 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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        food additive 16139
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            acetic acid 11060
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                hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester 1
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  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19909
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              atomic nucleus 19909
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                  main group element atom 19859
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                            organic group 18986
                              organic divalent group 18961
                                organodiyl group 18961
                                  carbonyl group 18917
                                    carbonyl compound 18917
                                      carboxylic acid 18641
                                        monocarboxylic acid 17979
                                          acetic acid 11060
                                            acetate ester 4060
                                              hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester 1
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