Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene
go back to main search page
Accession:CHEBI:75389 term browser browse the term
Definition:A dinitrile that is succinonitrile in which the methylene hydrogens at positions 2 and 3 are substituted by amino(phenylsulfanyl)methylidene groups. It acts as an inhibitor of MEK (mitogen activated protein kinase kinase).
Synonyms:exact_synonym: (2Z,3Z)-bis[amino(phenylsulfanyl)methylidene]butanedinitrile
 related_synonym: Formula=C18H14N4S2;   InChI=1S/C18H14N4S2/c19-11-15(17(21)23-13-7-3-1-4-8-13)16(12-20)18(22)24-14-9-5-2-6-10-14/h1-10H,21-22H2/b17-15+,18-16+;   InChIKey=BDLRGKKVJJEYLC-YTEMWHBBSA-N;   SMILES=N\\C(Sc1ccccc1)=C(C#N)/C(C#N)=C(\\N)Sc1ccccc1;   U0125
 xref: PMID:12121979 "Europe PMC";   PMID:12694865 "Europe PMC";   Reaxys:8073563 "Reaxys"


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        aetiopathogenetic role 18783
          carcinogenic agent 17773
            buta-1,3-diene 2062
              1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    main group molecular entity 19598
                      s-block molecular entity 19361
                        hydrogen molecular entity 19350
                          hydrides 18280
                            inorganic hydride 17204
                              pnictogen hydride 17166
                                nitrogen hydride 17003
                                  azane 16693
                                    ammonia 16690
                                      organic amino compound 16689
                                        amine 7579
                                          enamine 28
                                            1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.