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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phenyl biguanide
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Accession:CHEBI:75377 term browser browse the term
Definition:A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a phenyl group.
Synonyms:exact_synonym: N-phenylimidodicarbonimidic diamide
 related_synonym: 1-phenylbiguanide;   Formula=C8H11N5;   InChI=1S/C8H11N5/c9-7(10)13-8(11)12-6-4-2-1-3-5-6/h1-5H,(H6,9,10,11,12,13);   InChIKey=CUQCMXFWIMOWRP-UHFFFAOYSA-N;   N-phenyl-N'-guanylguanidine;   N-phenylbiguanide;   PBG;   SMILES=NC(=N)NC(=N)Nc1ccccc1;   phenyl diguanide
 xref: CAS:102-02-3;   LINCS:LSM-4586
 xref_mesh: MESH:C008846
 xref: PMID:3167692;   PMID:3786662;   PMID:4698519;   PMID:514692;   Reaxys:610553

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phenyl biguanide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tacr1 tachykinin receptor 1 increases response to substance EXP TACR1 protein results in increased susceptibility to phenyl biguanide CTD PMID:16982039 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
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  CHEBI ontology 19838
    role 19810
      application 19679
        pharmaceutical 19495
          drug 19520
            central nervous system drug 16785
              phenyl biguanide 1
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  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19722
                        carbon atom 19719
                          organic molecular entity 19719
                            heteroorganic entity 19474
                              organonitrogen compound 18800
                                guanidines 2332
                                  biguanide 1133
                                    phenyl biguanide 1
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