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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pararosaniline free base
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Accession:CHEBI:75372 term browser browse the term
Definition:An imine that is 4-methylidenecyclohexa-2,5-dien-1-imine in which both the hydrogens of the methylidene group are replaced by 4-aminophenyl groups. The hydrochloride salt is the histological dye 'pararosaniline'.
Synonyms:exact_synonym: 4,4'-[(4-iminocyclohexa-2,5-dien-1-ylidene)methanediyl]dianiline
 related_synonym: 4-(4,4'-diamino-benzhydrylidene)-cyclohexa-2,5-dienone-imine;   Basic Red 9;   Formula=C19H17N3;   InChI=1S/C19H17N3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20H,21-22H2;   InChIKey=AFAIELJLZYUNPW-UHFFFAOYSA-N;   SMILES=Nc1ccc(cc1)C(c1ccc(N)cc1)=C1C=CC(=N)C=C1;   basic fuchsin;   pararosaniline
 xref: CAS:479-73-2
 xref_mesh: MESH:C005409
 xref: Reaxys:2126685;   Wikipedia:Pararosaniline
 cyclic_relationship: is_conjugate_base_of CHEBI:87664


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pararosaniline free base term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO pararosaniline results in decreased activity of BCHE protein CTD PMID:16036213 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO pararosaniline inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression
decreases activity
ISO pararosaniline results in decreased expression of NR3C1 protein
pararosaniline results in decreased activity of NR3C1 protein
CTD PMID:19255438 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      application 19413
        dye 1309
          histological dye 160
            pararosaniline free base 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    main group molecular entity 19665
                      s-block molecular entity 19430
                        hydrogen molecular entity 19424
                          hydrides 18758
                            inorganic hydride 17457
                              pnictogen hydride 17432
                                nitrogen hydride 17277
                                  azane 17009
                                    ammonia 17008
                                      organic amino compound 17007
                                        aromatic amine 13676
                                          anilines 12355
                                            substituted aniline 11852
                                              pararosaniline free base 3
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