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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide
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Accession:CHEBI:75366 term browser browse the term
Definition:A sulfonamide that is 5-chloronaphthalene-2-sulfonamide in which one of the hydrogens of the nitrogen atom is substituted by a 4-aminobutyl group.
Synonyms:related_synonym: Formula=C14H17ClN2O2S;   InChI=1S/C14H17ClN2O2S/c15-14-5-3-4-11-10-12(6-7-13(11)14)20(18,19)17-9-2-1-8-16/h3-7,10,17H,1-2,8-9,16H2;   InChIKey=JJQKICOADUKSNS-UHFFFAOYSA-N;   SMILES=NCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1;   W-13;   W13
 xref: CAS:81705-04-6;   LINCS:LSM-2991
 xref_mesh: MESH:C033772
 xref: Reaxys:6227387
 cyclic_relationship: is_conjugate_base_of CHEBI:75369


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N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in decreased phosphorylation of BAD protein] CTD PMID:16935404 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Casp3 caspase 3 multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in increased cleavage of and results in increased activity of CASP3 protein]
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD PMID:16935404, PMID:27481217 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:27481217 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Hexb hexosaminidase subunit beta increases secretion
multiple interactions
EXP N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide results in increased secretion of HEXB protein
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Ionomycin results in increased secretion of HEXB protein]
CTD PMID:14499669 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions
ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide results in decreased expression of IL2RA protein
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Pentoxifylline results in decreased expression of IL2RA protein]
CTD PMID:1709825 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] CTD PMID:28887310 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        refrigerant 17418
          ammonia 16940
            organic amino compound 16939
              primary amino compound 7860
                N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              oxoacid 18193
                                chalcogen oxoacid 11482
                                  sulfur oxoacid 11085
                                    sulfonic acid 7333
                                      sulfonic acid derivative 7333
                                        sulfonamide 3168
                                          N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide 6
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