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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide
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Accession:CHEBI:75366 term browser browse the term
Definition:A sulfonamide that is 5-chloronaphthalene-2-sulfonamide in which one of the hydrogens of the nitrogen atom is substituted by a 4-aminobutyl group.
Synonyms:related_synonym: Formula=C14H17ClN2O2S;   InChI=1S/C14H17ClN2O2S/c15-14-5-3-4-11-10-12(6-7-13(11)14)20(18,19)17-9-2-1-8-16/h3-7,10,17H,1-2,8-9,16H2;   InChIKey=JJQKICOADUKSNS-UHFFFAOYSA-N;   SMILES=NCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1;   W-13;   W13
 xref: CAS:81705-04-6;   LINCS:LSM-2991
 xref_mesh: MESH:C033772
 xref: Reaxys:6227387
 cyclic_relationship: is_conjugate_base_of CHEBI:75369



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N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in decreased phosphorylation of BAD protein] CTD PMID:16935404 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Casp3 caspase 3 multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in increased cleavage of and results in increased activity of CASP3 protein]
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD PMID:16935404 PMID:27481217 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:27481217 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Hexb hexosaminidase subunit beta increases secretion
multiple interactions
EXP N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide results in increased secretion of HEXB protein
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Ionomycin results in increased secretion of HEXB protein]
CTD PMID:14499669 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions
ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide results in decreased expression of IL2RA protein
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Pentoxifylline results in decreased expression of IL2RA protein]
CTD PMID:1709825 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] CTD PMID:28887310 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link

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  CHEBI ontology 19740
    role 19713
      application 19546
        refrigerant 18119
          ammonia 17615
            organic amino compound 17615
              primary amino compound 8998
                N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide 6
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Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      chalcogen 19482
                        oxygen atom 19459
                          oxygen molecular entity 19459
                            hydroxides 19255
                              oxoacid 18635
                                chalcogen oxoacid 11751
                                  sulfur oxoacid 11375
                                    sulfonic acid 7667
                                      sulfonic acid derivative 7667
                                        sulfonamide 3222
                                          N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide 6
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