Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide
go back to main search page
Accession:CHEBI:75366 term browser browse the term
Definition:A sulfonamide that is 5-chloronaphthalene-2-sulfonamide in which one of the hydrogens of the nitrogen atom is substituted by a 4-aminobutyl group.
Synonyms:related_synonym: Formula=C14H17ClN2O2S;   InChI=1S/C14H17ClN2O2S/c15-14-5-3-4-11-10-12(6-7-13(11)14)20(18,19)17-9-2-1-8-16/h3-7,10,17H,1-2,8-9,16H2;   InChIKey=JJQKICOADUKSNS-UHFFFAOYSA-N;   SMILES=NCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1;   W-13;   W13
 xref: CAS:81705-04-6;   LINCS:LSM-2991
 xref_mesh: MESH:C033772
 xref: Reaxys:6227387
 cyclic_relationship: is_conjugate_base_of CHEBI:75369



show annotations for term's descendants           Sort by:
N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in decreased phosphorylation of BAD protein] CTD PMID:16935404 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Casp3 caspase 3 multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in increased cleavage of and results in increased activity of CASP3 protein]
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD PMID:16935404 PMID:27481217 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:27481217 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Hexb hexosaminidase subunit beta increases secretion
multiple interactions
EXP N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide results in increased secretion of HEXB protein
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Ionomycin results in increased secretion of HEXB protein]
CTD PMID:14499669 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions
ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide results in decreased expression of IL2RA protein
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Pentoxifylline results in decreased expression of IL2RA protein]
CTD PMID:1709825 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] CTD PMID:28887310 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19840
    role 19816
      application 19658
        NMR chemical shift reference compound 18005
          ammonia 17823
            organic amino compound 17823
              primary amino compound 9311
                N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19840
    subatomic particle 19838
      composite particle 19838
        hadron 19838
          baryon 19838
            nucleon 19838
              atomic nucleus 19838
                atom 19838
                  main group element atom 19788
                    p-block element atom 19788
                      chalcogen 19543
                        oxygen atom 19518
                          oxygen molecular entity 19518
                            hydroxides 19326
                              oxoacid 18761
                                chalcogen oxoacid 13774
                                  sulfur oxoacid 13561
                                    sulfonic acid 11598
                                      sulfonic acid derivative 11598
                                        sulfonamide 5301
                                          N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide 6
paths to the root