CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: methyltrioctylammonium
Accession: CHEBI:75293
browse the term
Definition: A quaternary ammonium ion with three octyl groups and one methyl group attached to the nitrogen.
Synonyms: related_synonym: Formula=C25H54N; InChI=1S/C25H54N/c1-5-8-11-14-17-20-23-26(4,24-21-18-15-12-9-6-2)25-22-19-16-13-10-7-3/h5-25H2,1-4H3/q+1; InChIKey=ZUZLIXGTXQBUDC-UHFFFAOYSA-N; N-methyl-N,N-dioctyl-1-octanaminium; SMILES=CCCCCCCC[N+](C)(CCCCCCCC)CCCCCCCC; methyltricaprylylammonium; tricaprylmethylammonium; trioctylmethylammonium
xref: Reaxys:4135558
G
Dio1
deiodinase, iodothyronine, type I
decreases activity
ISO
trioctylmethylammonium results in decreased activity of DIO1 protein
CTD
PMID:30561685
NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
G
Dio2
deiodinase, iodothyronine, type II
decreases activity
ISO
trioctylmethylammonium results in decreased activity of DIO2 protein
CTD
PMID:30561685
NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
G
Dio3
deiodinase, iodothyronine type III
decreases activity
ISO
trioctylmethylammonium results in decreased activity of DIO3 protein
CTD
PMID:30561685
NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
G
Iyd
iodotyrosine deiodinase
multiple interactions
ISO
trioctylmethylammonium inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
CTD
PMID:33352258
NCBI chr10:3,490,274...3,504,880
Ensembl chr10:3,490,240...3,504,877
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all