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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pipemidic acid
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Accession:CHEBI:75250 term browser browse the term
Definition:A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid substituted at position 2 by a piperazin-1-yl group and at position 8 by an ethyl group. A synthetic broad-spectrum antibacterial, it is used for treatment of gastrointestinal, biliary, and urinary infections.
Synonyms:exact_synonym: -ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
 related_synonym: 5,8-Dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid;   Formula=C14H17N5O3;   InChI=1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22);   InChIKey=JOHZPMXAZQZXHR-UHFFFAOYSA-N;   SMILES=CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCNCC1;   acide pipemidique;   acido pipemidico;   acidum pipemidicum
 xref: CAS:51940-44-4;   Drug_Central:2184;   HMDB:HMDB0041989;   KEGG:D08379;   LINCS:LSM-5267
 xref_mesh: MESH:D010876
 xref: PMID:16259938;   PMID:16908137;   PMID:20872568;   PMID:23799358;   PMID:28166217;   PMID:7178752;   Reaxys:626575;   VSDB:1904;   Wikipedia:Pipemidic_acid

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pipemidic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Pipemidic Acid CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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  CHEBI ontology 20072
    role 20026
      biological role 20025
        antimicrobial agent 17868
          quinolone antibiotic 610
            pipemidic acid 1
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  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19974
                    main group molecular entity 19974
                      s-block molecular entity 19774
                        hydrogen molecular entity 19766
                          hydrides 19135
                            inorganic hydride 17930
                              pnictogen hydride 17913
                                nitrogen hydride 17801
                                  azane 17556
                                    ammonia 17555
                                      organic amino compound 17555
                                        tertiary amino compound 9095
                                          N-arylpiperazine 3026
                                            pipemidic acid 1
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