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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pipemidic acid
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Accession:CHEBI:75250 term browser browse the term
Definition:A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid substituted at position 2 by a piperazin-1-yl group and at position 8 by an ethyl group. A synthetic broad-spectrum antibacterial, it is used for treatment of gastrointestinal, biliary, and urinary infections.
Synonyms:exact_synonym: -ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
 related_synonym: 5,8-Dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid;   Formula=C14H17N5O3;   InChI=1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22);   InChIKey=JOHZPMXAZQZXHR-UHFFFAOYSA-N;   SMILES=CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCNCC1;   acide pipemidique;   acido pipemidico;   acidum pipemidicum
 xref: CAS:51940-44-4;   Drug_Central:2184;   HMDB:HMDB0041989;   KEGG:D08379;   LINCS:LSM-5267
 xref_mesh: MESH:D010876
 xref: PMID:16259938;   PMID:16908137;   PMID:20872568;   PMID:23799358;   PMID:28166217;   PMID:7178752;   Reaxys:626575;   VSDB:1904;   Wikipedia:Pipemidic_acid

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pipemidic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Pipemidic Acid CTD PMID:17939016 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
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  CHEBI ontology 19770
    role 19720
      biological role 19720
        antimicrobial agent 17372
          quinolone antibiotic 589
            pipemidic acid 1
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  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    main group molecular entity 19662
                      s-block molecular entity 19429
                        hydrogen molecular entity 19423
                          hydrides 18758
                            inorganic hydride 17453
                              pnictogen hydride 17428
                                nitrogen hydride 17272
                                  azane 17003
                                    ammonia 17002
                                      organic amino compound 17001
                                        tertiary amino compound 8648
                                          N-arylpiperazine 2762
                                            pipemidic acid 1
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