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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pipemidic acid
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Accession:CHEBI:75250 term browser browse the term
Definition:A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid substituted at position 2 by a piperazin-1-yl group and at position 8 by an ethyl group. A synthetic broad-spectrum antibacterial, it is used for treatment of gastrointestinal, biliary, and urinary infections.
Synonyms:exact_synonym: -ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
 related_synonym: 5,8-Dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid;   Formula=C14H17N5O3;   InChI=1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22);   InChIKey=JOHZPMXAZQZXHR-UHFFFAOYSA-N;   SMILES=CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCNCC1;   acide pipemidique;   acido pipemidico;   acidum pipemidicum
 xref: CAS:51940-44-4;   Drug_Central:2184;   HMDB:HMDB0041989;   KEGG:D08379;   LINCS:LSM-5267
 xref_mesh: MESH:D010876
 xref: PMID:16259938;   PMID:16908137;   PMID:20872568;   PMID:23799358;   PMID:28166217;   PMID:7178752;   Reaxys:626575;   VSDB:1904;   Wikipedia:Pipemidic_acid

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pipemidic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Pipemidic Acid CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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  CHEBI ontology 19876
    role 19851
      biological role 19849
        antimicrobial agent 18048
          quinolone antibiotic 2080
            pipemidic acid 1
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  CHEBI ontology 19876
    subatomic particle 19874
      composite particle 19874
        hadron 19874
          baryon 19874
            nucleon 19874
              atomic nucleus 19905
                atom 19905
                  main group element atom 19821
                    main group molecular entity 19821
                      s-block molecular entity 19655
                        hydrogen molecular entity 19644
                          hydrides 19127
                            inorganic hydride 18102
                              pnictogen hydride 18090
                                nitrogen hydride 17995
                                  azane 17795
                                    ammonia 17794
                                      organic amino compound 17794
                                        tertiary amino compound 10125
                                          N-arylpiperazine 3421
                                            pipemidic acid 1
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