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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pridinol
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Accession:CHEBI:75247 term browser browse the term
Definition:A piperidine substituted at position 1 by a 3-hydroxy-3,3-diphenylpropyl group.
Synonyms:exact_synonym: 1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol
 related_synonym: 1,1-Diphenyl-3-(1-piperidyl)-1-propanol;   1,1-Diphenyl-3-piperidino-1-propanol;   3-(N-Piperidyl)-1,1-diphenyl-1-propanol;   Formula=C20H25NO;   InChI=1S/C20H25NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1-2,4-7,10-13,22H,3,8-9,14-17H2;   InChIKey=RQXCLMGKHJWMOA-UHFFFAOYSA-N;   SMILES=OC(CCN1CCCCC1)(c1ccccc1)c1ccccc1;   alpha,alpha-Diphenyl-1-piperidinepropanol;   alpha-(2-piperidinoethyl)benzhydrol;   pridinolum
 xref: CAS:511-45-5;   Drug_Central:2263;   KEGG:D08418;   LINCS:LSM-6559
 xref_mesh: MESH:C009185
 xref: PMID:17325466;   PMID:22051772;   PMID:3832136;   PMID:8102927;   Patent:EP1362585;   Patent:WO9624352;   Reaxys:252983;   Wikipedia:Pridinol


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pridinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO pridinol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
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G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO pridinol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        pharmaceutical 19272
          drug 19272
            antidyskinesia agent 1131
              antiparkinson drug 849
                pridinol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  organic heteromonocyclic compound 16444
                                    piperidines 7440
                                      pridinol 2
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