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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ornidazole
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Accession:CHEBI:75176 term browser browse the term
Definition:A C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 3-chloro-2-hydroxypropyl and methyl groups, respectively. It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections.
Synonyms:exact_synonym: 1-chloro-3-(2-methyl-5-nitro-1N-imidazol-1-yl)propan-2-ol
 related_synonym: 1-(2-hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole;   1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole;   Formula=C7H10ClN3O3;   InChI=1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3;   InChIKey=IPWKIXLWTCNBKN-UHFFFAOYSA-N;   Ro 7-0207;   SMILES=Cc1ncc(n1CC(O)CCl)[N+]([O-])=O;   alpha-(Chlormethyl)-2-methyl-5-nitro-imidazol-1-aethanol;   alpha-(chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol;   ornidazol;   ornidazolum
 xref: CAS:16773-42-5;   Drug_Central:1997;   KEGG:D05274;   LINCS:LSM-1548
 xref_mesh: MESH:D009950
 xref: PMID:15825069;   PMID:22529484;   PMID:23167572;   PMID:23571427;   PMID:28372197;   Patent:NL6606853;   Patent:US3435049;   Patent:US3493582;   Reaxys:614299;   Wikipedia:Ornidazole


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ornidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plau plasminogen activator, urokinase decreases expression EXP Ornidazole results in decreased expression of PLAU mRNA; Ornidazole results in decreased expression of PLAU protein CTD PMID:18998460 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
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Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        epitope 6835
          ornidazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  heteroarene 16447
                                    monocyclic heteroarene 13303
                                      azole 12471
                                        diazole 8126
                                          imidazoles 7655
                                            ornidazole 1
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