Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:75176 term browser browse the term
Definition:A C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 3-chloro-2-hydroxypropyl and methyl groups, respectively. It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections.
Synonyms:exact_synonym: 1-chloro-3-(2-methyl-5-nitro-1N-imidazol-1-yl)propan-2-ol
 related_synonym: 1-(2-hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole;   1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole;   Formula=C7H10ClN3O3;   InChI=1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3;   InChIKey=IPWKIXLWTCNBKN-UHFFFAOYSA-N;   Ro 7-0207;   SMILES=Cc1ncc(n1CC(O)CCl)[N+]([O-])=O;   alpha-(Chlormethyl)-2-methyl-5-nitro-imidazol-1-aethanol;   alpha-(chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol;   ornidazol;   ornidazolum
 xref: CAS:16773-42-5;   Drug_Central:1997;   KEGG:D05274;   LINCS:LSM-1548
 xref_mesh: MESH:D009950
 xref: PMID:15825069;   PMID:22529484;   PMID:23167572;   PMID:23571427;   PMID:28372197;   Patent:NL6606853;   Patent:US3435049;   Patent:US3493582;   Reaxys:614299;   Wikipedia:Ornidazole

show annotations for term's descendants           Sort by:
ornidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plau plasminogen activator, urokinase decreases expression EXP Ornidazole results in decreased expression of PLAU mRNA; Ornidazole results in decreased expression of PLAU protein CTD PMID:18998460 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        epitope 7009
          ornidazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic heterocyclic compound 18824
                                  heteroarene 16628
                                    monocyclic heteroarene 13606
                                      azole 12836
                                        diazole 8631
                                          imidazoles 7724
                                            ornidazole 1
paths to the root