Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ornidazole
go back to main search page
Accession:CHEBI:75176 term browser browse the term
Definition:A C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 3-chloro-2-hydroxypropyl and methyl groups, respectively. It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections.
Synonyms:exact_synonym: 1-chloro-3-(2-methyl-5-nitro-1N-imidazol-1-yl)propan-2-ol
 related_synonym: 1-(2-hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole;   1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole;   Formula=C7H10ClN3O3;   InChI=1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3;   InChIKey=IPWKIXLWTCNBKN-UHFFFAOYSA-N;   Ro 7-0207;   SMILES=Cc1ncc(n1CC(O)CCl)[N+]([O-])=O;   alpha-(Chlormethyl)-2-methyl-5-nitro-imidazol-1-aethanol;   alpha-(chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol;   ornidazol;   ornidazolum
 xref: CAS:16773-42-5;   Drug_Central:1997;   KEGG:D05274;   LINCS:LSM-1548
 xref_mesh: MESH:D009950
 xref: PMID:15825069;   PMID:22529484;   PMID:23167572;   PMID:23571427;   PMID:28372197;   Patent:NL6606853;   Patent:US3435049;   Patent:US3493582;   Reaxys:614299;   Wikipedia:Ornidazole


show annotations for term's descendants           Sort by:
 
ornidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plau plasminogen activator, urokinase decreases expression EXP Ornidazole results in decreased expression of PLAU mRNA; Ornidazole results in decreased expression of PLAU protein CTD PMID:18998460 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        epitope 6975
          ornidazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic molecule 19560
                              organic cyclic compound 19351
                                organic heterocyclic compound 18582
                                  heteroarene 16534
                                    monocyclic heteroarene 13436
                                      azole 12624
                                        diazole 8394
                                          imidazoles 7688
                                            ornidazole 1
paths to the root